85results about How to "Adjuvant therapy" patented technology

The invention discloses a non-invasive central arterial pressure detector, which comprises a pulse signal acquisition unit, a pulse signal processing unit, a main processor unit and an input and output unit, wherein the pulse signal acquisition unit is used for transmitting an acquired brachial arterial pressure pulse wave signal to the pulse signal processing unit; the pulse signal processing unit is used for processing the brachial arterial pressure pulse wave signal and then transmitting to the main processor unit; and the main processor unit is used for calculating and analyzing the received pressure pulse wave signal by using a conduction function method and transmitting a central arterial pressure curve, a central arterial pressure value, stroke volume, blood total resistance, an arteriosclerosis index and blood pressure type to the input and output unit to be displayed and output. A detection method comprises the following steps of: acquiring brachial arterial blood pressure through a blood pressure cuff wound on the brachial artery of the upper arm of a patient and patient information; acquiring brachial arterial pressure pulse wave when pressure of the blood pressure cuff is at 60 mmHg; and calculating and outputting central arterial pressure, the stroke volume, the blood total resistance, the arteriosclerosis index and the blood pressure type.

The invention relates to a radionuclide-labelled biodegradable bioabsorbable biopolymer nano fibrous membrane, a preparation process and application thereof. The preparation process includes steps of firstly adopting the electrostatic spinning technique to prepare a biopolymer nano fibrous membrane consisting of biopolymer nano fibers with diameters ranging from 50nm to 5000nm, performing chemical modification on the surface of the biopolymer nano fibrous membrane, enabling the surface of the biopolymer nano fibrous membrane to be in coupling reaction with double-functional-group coupling agent, chelating the surface of the biopolymer nano fibrous membrane after coupling reaction in buffer solution of acetic acid-sodium acetate anhydrous containing radionuclide compounds, and finally obtaining the radionuclide-labelled biodegradable bioabsorbable biopolymer nano fibrous membrane, wherein the double-functional-group coupling agent which is combined with amino in biopolymer nano fibers via chemical bonds on the surface of the biopolymer nano fibrous membrane, the radionuclide is chelated and fixed on the surface of the biopolymer nano fibrous surface via the double-functional-group coupling agent. The radionuclide-labelled biodegradable bioabsorbable biopolymer nano fibrous membrane can be used as an oncotherapy material or a material for focal tissue portions after tumor resection operation.

The invention discloses a system and an interactive method for obtaining medical information by an electronic or biological identification technology. Complete patient archives are formed for patients through an identity information storage unit and a medical information unit, and are stored in a cloud server; the corresponding patient archives can be called in real time from the cloud server through an identity identification unit, and an access link, a medical information two-dimensional code or a transmission interface medium used for transmission is formed; and the medical information is viewed in real time directly through using the access link, scanning the medical information two-dimensional code or accessing the transmission interface medium, and information communication of multiple users can be formed in an information interactive unit at the same time. According to the system and the method, the users can obtain complete medical records of themselves and hold the medical records for a long term; the medical records are repeatedly utilized and updated in real time, so that the system can obtain detailed information of diseases; online doctors can conveniently obtain standard and complete medical record data in the way and know conditions of related patients, so that the medical communication efficiency is improved; and the disease development conditions of the patients are tracked in real time, so that accurate diagnosis and treatment opinions can be provided.

The invention provides a healthcare pillow for treating periarthritis humeroscapularis and cervical spondylosis. A pillow inner is prepared by milling and filling a plurality of Chinese herbal medicines by mass ratio as follows: 50 parts of Chinese clematis, 50 parts of angelica, 30 parts of notoperygium root, 100 parts of selfheal spike, 50 parts of albizia flower, 50 parts of lily flower, 50 parts of rhodiola root, 30 parts of giant typhonium tuber, 20 parts of asarum, 20 parts of dahurian angelica, 50 parts of chrysanthemum, 50 parts of mulberry leaf, 20 parts of argyi leaf, 20 parts of bornel, 30 parts of magnet, 30 parts of chuanxiong rhizome, 30 parts of ganoderma lucidum, 30 parts of gastrodia tuber, 50 parts of chastetree fruit, 50 parts of acanthopanax bark, 30 parts of glossy privet fruit, 50 parts of ginseng flower, 30 parts of fructus liquidambaris, 30 parts of futokadsura stem, 30 parts of beefwood-like clubmoss herb and 10 parts of corn husk. The pillow is placed between the sixth cervical vertebra and the seventh cervical vertebra or at a tender point in use for treating and relieving the periarthritis humeroscapularis and hyperosteogeny, assisting in treating the cervical spondylosis and having certain efficacy on cardiovascular and cerebrovascular diseases.

The invention discloses a method and a system for monitoring patients by utilizing two channels. The method of the invention comprises the following steps: respectively receiving physiological signals of the patients detected by a first channel and a second channel; and carrying out relevance analysis on the physiological signals detected by the first channel and the second channel. The invention carries out relevance analysis on the physiological signals collected by the two channels, and records more information to assist a doctor to carry out early diagnosis and treatment.

The invention provides an anti-IMP type carbapenemase hybridoma cell strain, a monoclonal antibody and application. The hybridoma cell strain capable of stably secreting an anti-IMP type carbapenemaseantibody and a variable region sequence of the hybridoma cell strain are obtained by screening a mouse hybridoma monoclonal antibody and cloning an Ig variable region gene by an RT-PCR method, and the antibody binding specificity is identified by an ELISA method; the obtained anti-IMP type carbapenemase antibody can be used for detecting IMP type carbapenemase, the titer reaches 1:640000 or more,and the anti-IMP type carbapenemase antibody can be prepared into an in-vitro diagnostic kit or microfluidic chip for early typing of drug-resistant strains, guiding medication and assisted clinicalinfection control and treatment, and has important significance for improving the medical and health level of China.

The invention provides an electronic device for automatically selecting and opening acupuncture points with a midnight-midday ebb flow method, which solves the problems of inaccuracy and keenly feel, caused by that the acupuncture point selection is carried out through manual calculation, and the acupuncture point opening is carried out by using acupuncture and moxibustion in the conventional midnight-midday ebb flow method. A circuit board in a host shell is respectively connected with a micro-computer and a treatment head; the circuit board is provided with a functional treatment circuit respectively connected with a communication circuit, a treatment head driving circuit and a feedback circuit; the communication circuit is connected with the microcomputer; the treatment head driving circuit is connected with an electromagnetic coil; and the feedback circuit is connected with the functional treatment circuit and the treatment head driving circuit. An hour stem and time comparison table, a time zone deviation comparison table, a day celestial stem table, and an hour celestial stem and acupuncture point comparison table are stored in a memory. The acupuncture point selection is carried out by the following steps of: inputting y, M, d and C to calculate a median and find out a day celestial stem; finding out an hour stem by inputting time and a time zone; and finding out an acupuncture point and displaying.

The invention belongs to the field of medical health, and particularly relates to a novel protection gauze mask system. The novel protection gauze mask system comprises a face mask, wherein an artificial nose pipeline system functional module is arranged on the face mask, a respiration hole connected with noses is formed in one end of the artificial nose pipeline system, an inhaling filter and anexhaling disinfection filter are arranged at the other end of the artificial nose pipeline system, and the inhaling filter and the exhaling sterilizing filter are both provided with a one-way valve. The novel protection gauze mask system disclosed by the invention can provide safety protection for all kinds of staff, and can assist to perform detection, investigation and treatment of diseases through the respiratory system.

The invention discloses a detection primer for human IDH (isocitrate dehydrogenase) gene mutation and a detection reagent kit, which are used for the combination of PCR (polymerase chain reaction) and high resolution melting curve analysis technique. The detection reagent kit can be used for detecting the gene mutation on IDH 1 and IDH2 gene exon 4, detection samples are human genomes DNA (deoxyribonucleic acid) extracted from tumor tissues, blood or bone marrow cells, and the detection reagent kit is used for patients with clinical brain glioma and hematopathy to assist tumor diagnosis, treatment and judging prognosis. The detection reagent kit is easy and rapid in operation and good in detection effect.

The invention discloses a gluconic acid chlorhexidine composite gargle and a preparation method thereof. The gluconic acid chlorhexidine composite gargle is prepared from the following raw materials in parts by weight: 5.5-6 parts of polysorbate 80, 0.8-1.2 parts of metronidazole raw powder, 220-225 parts of ethyl alcohol, 310-315 parts of glycerinum, 275-300 parts of polyethylene glycol 400, 115-125 parts of gluconic acid chlorhexidine, 42.225-72.728 parts of auxiliary materials and a proper amount of purified water. The raw materials supplement one another and work together to play roles, and are capable of preventing and treating oral diseases in an assist manner and improving the oral nursing effect. According to the gluconic acid chlorhexidine composite gargle disclosed by the invention, the stability of the product is improved by adjusting the amount of auxiliary materials, the charging mode or even the charging order in the preparation process; the harmful substance parachloroaniline in the preparation process is greatly reduced; and the quality problems such as opacities and crystal separation easily generated by an existing gluconic acid chlorhexidine composite gargle in the preparation process are effectively solved.

The present invention discloses an application of a MLH1 gene, and a kit for detecting a gastrointestinal stromal tumor, wherein the kit comprises MLH1 gene sequencing primers. According to the present invention, the inventor finds that: the gastrointestinal stromal tumor is caused by the common KIT and PDGFRA gene mutations, and the MLH1 (V384D) mutation is one of the causes of the gastrointestinal stromal tumor, such that the kit for detecting the gastrointestinal stromal tumor can be provided for rapidly and accurately detecting the MLH1 mutation site of the gastrointestinal stromal tumor and assistedly diagnosing the gastrointestinal stromal tumor so as to assistedly treat the gastrointestinal stromal tumor based on the finding; and after the MLH1 (V384D) mutation is detected by using the kit, the gene targeting drug can be adopted to specifically treat patients, such that the use of the targeting drug is specific.

The invention discloses a cerebral neuron spike potential and local field potential combined depression detection method. The method comprises the following steps: respectively acquiring electroencephalogram data of a target object in a depression state and a non-depression state; performing feature fusion on the brain neuron spike potential data and the local field potential data corresponding to the same electroencephalogram data to obtain fused electroencephalogram data; training an ensemble learning network based on the training data, determining an optimal network parameter, and optimizing the ensemble learning network based on the optimal network parameter; and performing classification prediction on the current electroencephalogram data of the target object based on an integrated learning network, performing voting selection on each output classification prediction result, and determining the depression state of the target object based on a final classification result. According to the method, the final prediction result is comprehensively obtained through result voting selection of the three classifiers by utilizing the advantages of integrated learning in combination with different classifiers. The characteristics in the signals can be effectively extracted, and the depression state can be accurately judged.

The invention discloses a mutational COL4A5 gene and application thereof, in particular to a method for the detection of Alport syndrome mutations of the COL4A5 gene. The encoded IV-type collagen alpha 5 serine on 1371 site is mutated into a terminator under action of mutation of the COL4A5 gene and truncated IV-type collagen alpha 5 chain is caused. The mutational COL4A5 genes or the mutational IV-type collagen alpha 5 chain is used in the preparation of an AS detection agent or a detection device. The detection device preferably comprises a detection platform including a gene chip containing a COL4A5 gene for detecting mutations. The mutational COL4A5 gene provides the pathogenic loci of AS novel pathogenic genes, and provides a new molecular biological basis for the diagnosis of the disease.

The invention provides an anti-VIM type carbapenemase hybridoma cell strain, a monoclonal antibody and application. The hybridoma cell strain capable of stably secreting the anti-VIM type carbapenemase antibody and a variable region sequence of the hybridoma cell strain are obtained by screening a mouse hybridoma monoclonal antibody and cloning an Ig variable region gene by an RT-PCR method. Through systematic evaluation, the anti-VIM type carbapenemase monoclonal antibody has better performance in all aspects, so that the anti-VIM type carbapenemase monoclonal antibody is suitable for being used as an immunodiagnostic reagent for in vitro diagnosis of VIM type carbapenemase, and the titer reaches 1: 1280000 or above; and a prepared kit or microfluidic chip can be used for early typing of drug-resistant strains, guiding medication and assisting clinical infection control and treatment.

The invention provides a retina anomaly analysis method and equipment. The method comprises the steps of conducting feature extraction on at least one fundus image through a feature extraction module; recognizing the extracted features through a region detection module, wherein the region detection module comprises a category branch and a regression branch, the category branch is used for obtaining region category information according to the features, and the regression branch is used for obtaining region position information according to the features; identifying the features through an overall anomaly detection module to obtain overall anomaly category information; segmenting a region corresponding to the region category information to obtain region area information; and carrying out statistical analysis on the region category information, the region area information, the region position information and the overall anomaly category information corresponding to the at least one fundus image to obtain anomaly correlation data which is used for reflecting a corresponding relationship between various overall anomaly categories and various region categories as well as the region area information and the region position information of the various region categories.

The invention provides a traditional Chinese medicine compounded liquid sanitary napkin. An inner core of the sanitary napkin is prepared from a novel liquid material through curing, mold pressing andscissoring, wherein the novel liquid material is prepared through mixing purified water, a traditional Chinese medicine extract and a nano super-absorbent polymer according to a certain ratio, carrying out emulsifying and carrying out homogenizing; and the traditional Chinese medicine extract is prepared from the following raw materials: herba leonuri, aloe vera, radix astragali, rhizoma Chuanxiong, artemisia argyi, cortex phellodendri, radix sophorae flavescentis, herba houttuyniae and fructus cnidii. The liquid sanitary napkin provided by the invention is dryer and clearer in surface layer,more superior in absorption property and free of side leakage; the menstruation absorption time of the liquid sanitary napkin is relatively short and is only 3 seconds on an average, and a consumer has skin-fitting feeling, comfort feeling and non-foreign sense in wearing; and meanwhile, the liquid sanitary napkin further has the actions of resisting bacteria, diminishing inflammations, relievingitching, regulating turbulence of vaginal florae, relieving primary dysmenorrhea, increasing the quantity of vaginal lactobacilli and improving immunologic functions of organisms, thereby being lovedand pursued by extensive female consumers.

The invention provides an anti-KPC type carbapenemase hybridoma cell strain, a monoclonal antibody and application. The hybridoma cell strain capable of stably secreting the anti-KPC type carbapenemase antibody and a variable region sequence of the hybridoma cell strain are obtained by screening a mouse hybridoma monoclonal antibody and cloning an Ig variable region gene by an RT-PCR method. Through systematic evaluation, the anti-KPC type carbapenemase monoclonal antibody has better performance in all aspects, so that the anti-KPC type carbapenemase monoclonal antibody is suitable for being used as an immunodiagnostic reagent for in vitro diagnosis of KPC type carbapenemase, and the titer reaches 1: 1280000 or above; and a prepared kit or microfluidic chip can be used for early typing of drug-resistant strains, guiding medication and assisting clinical infection control and treatment.

The invention discloses a drug addiction treatment medicine smoking device. The drug addiction treatment medicine smoking device at least contains drug addiction treatment medicine, and the drug addiction treatment medicine smoking device is constructed to be applicable to sucking components of the drug addiction treatment medicine along with carrying gas under the non-combustion condition into the human body. The invention further discloses a cigarette filter tip, wherein the cigarette filter tip contains the drug addiction treatment medicine, smoke obtained after tobacco is combusted flows through the drug addiction treatment medicine so that the components of the drug addiction treatment medicine along with the smoke enters the mouth of the human body under the non-combustion condition.The invention further discloses a cigarette comprising the cigarette filter tip. In this way, a drug addict sucks the drug addiction treatment medicine in the conscious or unconscious smoking process, and the auxiliary treatment effect can be achieved at least.

The invention provides an occult blood detection film and a preparation method and application thereof and an occult blood detection kit, and relates to the technical field of occult blood detection.The preparation method of the occult blood detection film comprises the following steps: providing a polyion film; and immersing the polyion film into a dye, so that the dye is attached to the polyionfilm to obtain the occult blood detection film, wherein the dye is suitable for reacting with hemoglobin, the colors of the dye are different in environments with different hemoglobin concentrations,and the dye comprises at least one of methylene blue dye or procyanidine dye. The method has the characteristics of simple operation, strong anti-interference performance, obvious color development change, fast detection and the like, and can alleviate the problems of high technical requirements, high cost, complex detection and the like in occult blood detection in the prior art.

The invention relates to a primer, a probe, a composition and a method for screening 14 fusion genes related to acute promyelocytic leukemia by using a real-time fluorescent quantitative PCR technology. The screened related fusion genes comprise PML-RAR[alpha], PLZF-RAR[alpha], NuMA-RAR[alpha], STAT5b-RAR[alpha], NPM-RAR[alpha], TBLR1-RAR[alpha], PRKAR1A-RAR[alpha], FNDC3B-RAR[alpha], BCOR-RAR[alpha], FIP1L1-RAR[alpha], IRF2BP2-RAR[alpha], STAT3-RAR[alpha], GRF2I-RAR[alpha] and NABP1-RAR[alpha]. The real-time fluorescence PCR technology is combined with the Tapman probe, common or uncommon APLdisease related fusion genes are integrated together for screening, diagnosis, treatment and prognosis monitoring of APL diseases can be assisted more comprehensively, and compared with previous methods such as FISH, the method has higher precision and facilitates result interpretation. Moreover, the primers and the probes are reasonably proportioned and optimized, and the detection conditions are optimized, so that the efficiency is greatly improved.

The invention discloses a low-sugar health food, made by mixing naked oat flour, buckwheat flour, soybean flour, mung bean flour, black bean flour, whey protein flour, edible salt, Artemisia sphaerocephala gum, fruit and vegetable juice, and traditional Chinese medicine decoction to obtain dough, curing the dough, sheeting, cutting into strips, drying, cutting off, and packaging to obtain the low-sugar health food. The materials for the low-sugar health food are diverse; the low-sugar health food has low sugar content, features health effects of the ingredients such as naked oat, buckwheat, soybean, mung bean and black bean, and can be consumed often to effectively adjust glucose, improve eyesight, improve body immunity, maintain body physiological equilibrium and prevent and treat diabetes mellitus. The low-sugar health food as a novel nutrient healthy green flour food that is purely natural with smooth and delicious taste is provided for the public, especially diabetics.