118 results about "Hb - Hemoglobin" patented technology

The invention provides a transcranial deep electrical stimulation closed-loop regulation and control system and method based on fNIRS dynamic guidance. The method comprises the steps that a transcranial alternating current electrical stimulation module applies an electrical signal to a target deep brain region according to preset parameters to carry out electrical stimulation regulation and control; the synchronous triggering module is used for realizing millisecond-level synchronization of a stimulation task and near-infrared brain function data acquisition; the brain function monitoring module analyzes the concentration change of cortex oxyhemoglobin in real time through the multi-channel head cap; the electrical stimulation-response coupling mapping module positions a significant activation channel by adopting statistical test, and establishes an oxyhemoglobin concentration variable and electrical stimulation current amplitude quantitative model; and the dynamic parameter adjusting module optimizes the output current in real time. Personalized closed-loop regulation and control of non-invasive deep brain stimulation can be achieved, cerebral cortex blood oxygen signals are monitored in real time through near-infrared brain function imaging, stimulation parameters are dynamically adjusted, and the accuracy and individualization level of deep brain stimulation are remarkably improved.

The invention relates to methods, devices, and software for distinguishing hemoglobin (Hb) from myoglobin (Mb) in urine samples using peroxidase-reactive test strips. A time-resolved video of the color change on the test pad is recorded, and hue values are extracted and analyzed over time. Diagnostic differentiation between Hb and Mb is achieved by evaluating the hue-time curve, in particular via endpoint hue values and the ratio of integrated hue values in distinct time intervals. The invention further comprises a standardized optical setup for recording, a software-based evaluation algorithm, and a refillable cartridge for in-situ urine analysis devices containing appropriate test fields. The invention enables combined testing with additional urine parameters and is suitable for medical and non-clinical applications such as sport and home diagnostics.

The invention relates to the technical field of medical detection, in particular to a microneedle array-containing S100A9 sample sampling and detecting device which comprises a base, a limiting column and a color developing assembly, the limiting column is fixedly connected to the top end of the base, and a working sliding groove for inserting the color developing assembly is formed between the limiting column and the base; a sampling groove is formed in the top end of the base, the inner bottom wall of the sampling groove is fixedly connected with a microneedle assembly used for puncturing the skin of a patient for sampling, and the top of the microneedle assembly communicates with a pretreatment assembly used for filtering an extracted sample; driving force is provided for the pretreatment assembly in the process that the color developing assembly is inserted into the working sliding groove, and the filtered sample is input into the color developing assembly to be detected. According to the invention, convenient sampling is realized through the microneedle assembly, and a sample is pertinently filtered by using the pretreatment assembly, so that macromolecular interference impurities such as cell debris and hemoglobin are effectively removed, the interference on S100A9 detection is reduced, and the accuracy and reliability of S100A9 detection are improved.

The invention provides a palm vein high-security identity authentication system based on spectral analysis and deep learning, and relates to the technical field of biological recognition, the system comprises a hardware layer, a data processing layer, an algorithm layer and an application layer, through an antagonistic living body detection module in the algorithm layer, in combination with physical modeling and a GAN (Generative Adversarial Network), the high-security identity authentication of a complex imitation is realized. The method comprises the following steps: carrying out effective identification of a high-biomimetic material, carrying out physical modeling to analyze the absorption characteristics of palm veins in a hyperspectral range, such as the difference between oxyhemoglobin and oxyhemoglobin and periodic spectrum micro-interference caused by heart rate, and providing living body evidence based on physiological dynamics; meanwhile, a high-simulation template sample generated by the GAN is used for training a discriminator, the insight ability of the system to a template means is further enhanced, and compared with single traditional texture or static signal detection, the system combines physical characteristics with deep learning, and the confidence coefficient of in-vivo detection reaches up to 99.99%.

The invention discloses an anticoagulant sample agglutination detection device for hemoglobin analysis, and relates to the technical field of biomedical detection.The anticoagulant sample agglutination detection device comprises a machine shell, a blood collection tube and a machine cover rotationally installed on the machine shell, and further comprises a plurality of laser receiving plates rotationally installed on the machine cover and a light blocking cylinder fixedly installed in the machine shell; a support is installed in the machine shell through a damping support, a motor is fixedly installed on the support, a rotating disc is rotatably installed on the support, a storage disc is fixedly installed on the rotating disc, and a plurality of sets of tube frame stations used for storing blood collection tubes are installed on the storage disc. The method has the advantages that the centrifugal light transmittance is adopted to detect the agglutination condition in the blood sample, multiple batches of samples can be detected at a time, the detection efficiency is higher, the detection has higher real-time performance, the detection result is more accurate, the horizontal position of agglutination can be judged, and the type of agglutination can be judged according to the agglutination position.

The utility model relates to the technical field of medical detection devices, and discloses a glycosylated hemoglobin detection device, which comprises a sampling mechanism, a detection mechanism and a control mechanism, the sampling mechanism comprises an injection pump set, a sampling needle and a sampling valve, the sampling valve is a six-way sampling valve, the injection pump set is connected with a first port of the sampling valve, and the sampling needle is connected with a second port of the sampling valve; the separation mechanism comprises an eluent group, a mixer and a chromatographic separator, the eluent group is connected with a fifth port of the sample injection valve, the chromatographic separator is connected with a sixth port of the sample injection valve, and two ends of the mixer are connected with a third port and a fourth port of the sample injection valve; the inspection mechanism comprises a filter and an inspector, the filter is arranged between the mixer and the chromatographic separator, and the inspector is connected with the chromatographic separator. According to the utility model, the glycosylated hemoglobin can be rapidly and accurately detected through an accurate sample introduction and separation mechanism, so that the detection efficiency is improved. The automation degree of the detection process is high, the requirement for manual operation is reduced, and the possibility of human errors is reduced.

To provide a color and shape change monitoring system capable of accurately monitoring the color and shape change of a human body caused by a blood flow change.SOLUTION: The image processing apparatus includes a three dimensional point cloud data acquisition unit configured to acquire three dimensional point cloud data of a measurement target portion of a human body, a color data acquisition unit configured to acquire color data of the measurement target portion, a color-shape-data generation unit configured to generate color-shape data of the measurement target portion in which the color data is associated with the three dimensional point cloud data, and a pigment component separation unit configured to separate the color-shape data into a hemoglobin pigment component, a melanin pigment component, and a shade component.SELECTED DRAWING: Figure 1

A method of implementing changes in deoxyhemoglobin concentration, the method comprising: targeting a sequence of partial pressures of oxygen in arterial blood (PaCh) values in a subject using a sequential gas delivery device in a periodic input pattern; measuring a blood-oxygen level dependent (BOLD) signal in a voxel of the subject's brain using a magnetic resonance imaging device while targeting the sequence of values; comparing the pattern to the signal; and determining a vascular tissue characteristic (vessel type, vessel orientation, or pathological condition) for the voxel based on the comparison.

To provide a blood glucose level measuring device and a blood glucose level measuring method capable of accurately measuring a blood glucose level of a living body.SOLUTION: A blood glucose level measuring device 1 includes: a light output unit 3 that outputs measurement light L to a living body 6; a light detection unit 4 that detects the measurement light L transmitted through the living body 6; a temporal phase difference calculation unit that calculates a temporal phase difference between an oxygenated hemoglobin waveform related to an oxygenated hemoglobin concentration of blood of the living body 6 and a deoxygenated hemoglobin waveform related to a deoxygenated hemoglobin concentration of the blood of the living body 6, based on a detection result of the light detection unit 4; a blood glucose level calculation unit that calculates a blood glucose level of the living body 6 based on the temporal phase difference; and a reliability estimation unit that estimates the reliability of the temporal phase difference. The reliability estimation unit estimates that the reliability of the temporal phase difference is lower as an SN ratio of the detection result of the light detection unit 4 is smaller.SELECTED DRAWING: Figure 1

The invention discloses a split-type glycosylated hemoglobin analysis device, and relates to the field, the split-type glycosylated hemoglobin analysis device comprises a host and a split-type isolation cover, the top of the host is provided with a modular analysis part, and the upper edge of the modular analysis part is provided with four modular assembly ports; a sample tube, a first analysis module, a second analysis module and a cleaning module are detachably assembled in the four modular assembly ports respectively, the split type isolation hood is detachably assembled above the main machine, and a control part and a sampling device are mounted at the positions, above the modular analysis part, in the split type isolation hood; the control part can control the sampling device to respectively move to a first position, a second position, a third position and a fourth position. A split modular mounting structure is adopted, and the sample tube, the first analysis module, the second analysis module and the cleaning module in the device can be taken out from modular assembly ports in the modular analysis part, so that the modules are more convenient to replace, clean and disinfect.

Disclosed are an apparatus and method for estimating a target component value. The apparatus for estimating a target component value may include: a sensor configured to obtain a spectrum of light scattered or reflected from an object; and a processor configured to correct a first reflectance value of the spectrum based on a melanin index; obtain a second reflectance value based on the correction of the first reflectance value; convert the second reflectance value into an absorbance value; estimate the target component value based on the absorbance value; and correct the target component value based on a hemoglobin index.

This disclosure relates to a method and device for determining the hemoglobin level of a mammal. The device includes several light-emitting diodes, one or more sensors, and a processor.

The application discloses an imaging method for fusing photon weight and diffuse light brain tissue blood oxygen concentration change quantity and related products, and relates to the technical field of biological tissue blood oxygen imaging. The method comprises the following steps: acquiring experimental data obtained by irradiating a measured tissue with light sources of two wavelengths; performing the following calculation on the experimental data corresponding to each wavelength of the light source: calculating the average photon transmission path of the kth light probe combination in the ith voxel unit by using a formula; calculating the photon weight of the kth light probe combination in the ith voxel unit by using a formula; calculating the change quantity of the tissue absorption coefficient of the ith voxel unit by using a formula; and finally calculating the change quantity of the concentrations of oxyhemoglobin and deoxyhemoglobin by using the calculation data obtained by the two wavelengths. The application proposes a method for fusing photon weight, and by means of weight calculation, the accurate brain tissue blood oxygen concentration change quantity can be obtained by using a small amount of S-D combination photon signals.

1. The name of the design product: blood analyzer (SZH-MF03A). 2. The use of the design product: for testing the concentration of blood glucose, uric acid, hemoglobin in blood samples. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

A blood analyzer and a hemoglobin detection method, the method comprising: a control device controls a sampling device (11) to obtain a sample to be tested (201); a control device controls a sample preparation device (12) to mix a portion of the sample to be tested with a first reagent to prepare a first sample liquid to be tested, and a control device controls a portion of the sample to be tested with a second reagent to prepare a second sample liquid to be tested (202); a control device controls a colorimetric detection device (13) to perform a hemoglobin detection on the first sample liquid to be tested using a colorimetric method to obtain a first measurement value (203); a control device controls an optical detection device (14) to perform a hemoglobin detection on the second sample liquid to be tested using a light scattering method to obtain a second measurement value (204); and a control device determines whether the sample to be tested is a sample with a falsely high hemoglobin level (205); if the sample to be tested is a sample with a falsely high hemoglobin level, the control device outputs a second measurement value (206); if the sample to be tested is a sample with a falsely high hemoglobin level, the control device outputs a first measurement value (207).

The invention relates to the technical field of blood detection, and particularly discloses a spectrum detection method, system, device, equipment and medium for detecting the free hemoglobin content of a plasma braid, and the method comprises the following steps: taking out a to-be-detected sample of the plasma braid to obtain an original optical measurement object to obtain the to-be-detected sample; performing multi-wavelength alternate irradiation on the to-be-detected sample and collecting continuous time sequence photoelectric response to obtain an original time sequence signal set; obtaining an absorbance set; a normalized absorption characteristic subjected to scattering and temperature dual compensation is obtained; obtaining an initial free hemoglobin concentration estimated value; the final free hemoglobin concentration and a judgment result are obtained; by directly detecting the separated plasma tube braid, the sealing performance and safety of the main blood bag are not influenced at all, and the pollution risk caused by puncture sampling is thoroughly avoided. The method is objective and accurate, results are quantified, manual subjective errors are thoroughly eliminated by adopting a spectral analysis technology, and particularly, judgment on critical value samples is extremely accurate.

The invention discloses a blood microscopic imaging detection and blood evaluation method and device. The method comprises the following steps: preparing blood into a microscopic examination sample; adding a microscopic examination sample into the cavity of the detection chip; irradiating the detection chip cavity by using a light source A; shooting to obtain a microscopic examination sample image; detecting to obtain an image of a single red blood cell in the microscopic examination sample image, and obtaining the volume of the single red blood cell and the hemoglobin parameter of the single red blood cell according to the image of the single red blood cell; storing the volume and hemoglobin parameters of a single red blood cell; calculating the number of single red blood cells in the shot picture, and if the number of single red blood cells in the shot picture does not reach the set measurement number, moving the position of the detection chip cavity corresponding to shooting, changing the position of the X coordinate or the Y coordinate, and obtaining the volume of single red blood cells of red blood cells with the set measurement number and corresponding hemoglobin parameters.

A non-invasive biosignal measurement device based on skin effect removal, includes: a signal measurement instrument measuring a PPG signal of a measurement subject in contact with the skin on one side of a specific body part of the measurement subject; a signal reception unit receiving the PPG signal from the signal measurement instrument; and a ratio value calculation unit removing noise due to a skin effect from the PPG signal, and then calculating ratio values at different wavelengths for measuring a biosignal including blood sugar and glycated hemoglobin of the measurement subject. The signal measurement instrument includes a first sensor module including an optical barrier and a second sensor module for removing the skin effect.

To provide an image processing device that estimates spectral reflectance, enabling more accurate reproduction of skin color than conventional methods. [Solution] An image processing apparatus comprising: a skin pigment estimation unit that estimates the amount of melanin and hemoglobin components in the skin region of a person in a target image; a spectral reflectance estimation unit that estimates the spectral reflectance of the skin region based on the amount of melanin and hemoglobin components estimated by the skin pigment estimation unit; and a spectral reflectance correction unit that corrects the spectral reflectance estimated by the spectral reflectance estimation unit based on a generated image generated using the spectral reflectance estimated by the spectral reflectance estimation unit and the target image.

The application provides a molecular marker related to immune traits of Lake sheep, a detection method and application thereof. Through PCR amplification and sequence analysis of a PD-L1 gene of the Lake sheep, a G / A polymorphic site at the 135th position of the amplified fragment is found, further detection of the polymorphic site of 898 Lake sheep is carried out by using KASPar primers, a least square model is established, and correlation analysis of the genotype and growth traits is carried out, and finally it is determined that the amplified PD-L1 gene fragment can be used as a molecular marker of immune traits related to the total number of red blood cells and the average concentration of hemoglobin of red blood cells of the Lake sheep. Through detection of the molecular marker, the application can be used for disease-resistant breeding of the Lake sheep, so as to guarantee the health of the Lake sheep and help to increase economic benefits.

In at least one embodiment, a hemoglobin measuring device may include a plurality of sensors, a display configured to present information, and a computing device in communication with the sensors and display and having a processor and a memory storing instructions executable by the processor. The instructions may include instructions to receive, from the sensors, measurements of one or more forms of glycated hemoglobin in a blood samples, determine a total fetal hemoglobin value in the blood sample by performing a peak area summation of all forms of fetal hemoglobin, subtract the total fetal hemoglobin value from 100 to derive a total adult hemoglobin value, determine a glycated fetal hemoglobin value, compare the glycated fetal hemoglobin value to a reference range to obtain a comparison, determine a baseline glucose control value based on the comparison, and output the baseline glucose control value and the comparison to a display for medical evaluation.

1. The name of the design product: blood analyzer (SZH-MF01A). 2. The use of the design product: for testing the concentration of blood glucose, uric acid, hemoglobin in blood samples. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

The invention discloses an image processing method and device for judging suspension red blood cell hemolysis. The method comprises the following steps: acquiring a blood image set; the blood image set comprises a plurality of blood images and corresponding label information; acquiring a blood parameter information set; the blood parameter information set comprises a plurality of blood parameters and corresponding label information; the blood parameters comprise hemoglobin concentration, reticulocyte concentration, indirect bilirubin concentration, lactic dehydrogenase concentration and globin concentration; utilizing the blood image set and the blood parameter information set to construct a blood hemolysis composite detection model; based on the blood hemolysis composite detection model, processing the collected blood image and blood parameters to obtain hemolysis detection result information; the hemolysis detection result information is used for representing erythrocyte hemolysis information of the blood corresponding to the collected blood image and blood parameters.

Absorbance is used to measure hemoglobin and bilirubin parameters in whole blood samples.SOLUTION: System 10 includes an optical-sample module 20, a spectrometer module 100, a fiber-optic assembly 90 that optically connects optical-sample module 20 to spectrometer module 100, and a processor module 150. The optical-sample module 20 includes a light-emitting module having an LED light source, a cuvette assembly, and a calibration-light module. Processor module 150 receives and processes electrical signals from spectrometer module 100 and converts the electrical signals into output signals usable to display and report hemoglobin parameter values and / or total bilirubin parameter values for a whole blood sample.SELECTED DRAWING: Figure 1

The invention provides a hemolysis index quality control product as well as a preparation method and application thereof. The hemolysis index quality control product provided by the invention comprises serum, a preservative and a hemolysis component, the serum, the preservative and the hemolysis component are mixed in advance according to different preset proportions to obtain quality control products with different hemolysis indexes; the hemolysis component is a blood sample with damaged red blood cells or a hemoglobin standard substance; the preservative is 0.05% of sodium azide. The hemolysis index quality control product provided by the invention can be used for monitoring the reaction and detection capability of a clinical laboratory inspection instrument on a hemolysis sample, and can also be used for assisting biochemical detection, analysis and judgment.

The present invention relates to a device and a method for determining the hematocrit and / or hemoglobin level of a liquid flowing in a tubular portion (2), the method comprising: emitting a light beam in the direction of the tubular portion (2) with at least two light sources (11; 21), each of the two light sources (11; 21) being configured to emit a light beam at an emission wavelength selected to correspond to the isosbestic point of hemoglobin; receiving light signals transmitted through the tubular portion (2) with at least two light sensors (12; 22), each light sensor (12; 22) being associated with one of the two light sources (11; 21); calculating the hematocrit or hemoglobin level in the liquid by processing the light signals received by the light sensors (12; 22); characterized in that, when determining the hematocrit level and / or hemoglobin level, the emission power of at least one light source (11; 21) is adjusted according to the calculated hematocrit and / or corresponding hemoglobin level of the liquid.

The utility model discloses a rapid hemoglobin detection device, which relates to the technical field of clinical medicine, and comprises a device shell, the upper end of the device shell is provided with a display screen and a control button, and the upper end of the device shell is provided with an inner groove; according to the rapid hemoglobin detection device, when a detection opening needs to be detected, a sliding block is moved to drive a limiting block to be separated from the interior of a limiting hole, a connecting block and a positioning block are pulled upwards, a sealing plate is opened, the detection opening is put into a reagent card for detection, then the sealing plate is closed, and the arc-shaped surface of the positioning block and the arc-shaped surface of the limiting block are extruded; the limiting block is extruded into the sliding groove, and the limiting block is inserted into the limiting hole under the elastic potential energy of the supporting spring, so that the connecting block is limited, the sealing plate is tightly closed, the detection port is prevented from being in contact with the external environment, the sealing effect is good, errors are not likely to exist in the detection process, and the accuracy of the detection structure can be ensured.

A demand-adapting and auto-regulatory ECMO system and method is disclosed that may be configured to provide complete cardiopulmonary replacement. The system and method employ a blood gas exchanger having a blood inlet, a blood outlet, a gas inlet, and a gas outlet, an oxygen sensor positioned to detect oxyhemoglobin saturation at the blood inlet, and a carbon dioxide sensor positioned to detect exhaust gas CO2 concentration at the gas outlet. A controller communicates with the oxygen sensor and the carbon dioxide sensor and controls blood flow and gas flow through the blood gas exchanger in response to a sensed oxygen level by the oxygen sensor and a sensed carbon dioxide level by the carbon dioxide sensor, in turn maintaining the sensed oxygen level and the sensed carbon dioxide level within a pre-designated range of values to maintain a patient's metabolic requirements.

This application relates to the field of medical image processing technology, specifically to a hemoglobin emphasis device and method for endoscopes. The device includes a light source unit; an imaging unit for acquiring reflected light signals from a target area under multispectral illumination and outputting a raw Bayer format image or an RGB color image; and an image processing unit for receiving and processing the output Bayer format image or RGB color image, comprising at least: a spectral reconstruction module for calculating and reconstructing a single-band image signal using a spectral reconstruction model; a hemoglobin concentration calculation module configured to calculate a relative hemoglobin concentration based on the image signal; and an image enhancement module configured to perform pixel-level gain adjustment on the raw color image or the processed image, convert it to a set color space for contrast mapping, and finally output a hemoglobin-emphasized image. The image output by this invention can significantly improve the contrast between blood vessels and surrounding tissues.

The present application belongs to the field of gas detection, and relates to a combined detection tube for detecting carbon monoxide concentration in blood. The device of the present application is composed of a sample adding tube and a detection tube. The filler section arranged in the sample adding tube can effectively destroy red blood cells to release CO gas under the action of Cr(VI) / Cr(III) redox system, and at the same time, the reducing substances such as glutathione (GSH) and ascorbic acid in blood are removed through the interference removal section, thereby significantly improving the specificity and accuracy of detection. The indicating glue section in the detection tube adopts a platinum-selenium compound and a potassium iodate system, which occurs a color reaction in the presence of CO: I2O5+5CO→I2+5CO2, and the generated iodine element presents a brown color development band, the length of which is positively correlated with the concentration of HbCO, so as to realize the visual quantitative analysis of the content of carboxyhemoglobin in blood.