74 results about "Hb - Hemoglobin" patented technology

The invention relates to the technical field of medical detection, in particular to a microneedle array-containing S100A9 sample sampling and detecting device which comprises a base, a limiting column and a color developing assembly, the limiting column is fixedly connected to the top end of the base, and a working sliding groove for inserting the color developing assembly is formed between the limiting column and the base; a sampling groove is formed in the top end of the base, the inner bottom wall of the sampling groove is fixedly connected with a microneedle assembly used for puncturing the skin of a patient for sampling, and the top of the microneedle assembly communicates with a pretreatment assembly used for filtering an extracted sample; driving force is provided for the pretreatment assembly in the process that the color developing assembly is inserted into the working sliding groove, and the filtered sample is input into the color developing assembly to be detected. According to the invention, convenient sampling is realized through the microneedle assembly, and a sample is pertinently filtered by using the pretreatment assembly, so that macromolecular interference impurities such as cell debris and hemoglobin are effectively removed, the interference on S100A9 detection is reduced, and the accuracy and reliability of S100A9 detection are improved.

The invention provides a palm vein high-security identity authentication system based on spectral analysis and deep learning, and relates to the technical field of biological recognition, the system comprises a hardware layer, a data processing layer, an algorithm layer and an application layer, through an antagonistic living body detection module in the algorithm layer, in combination with physical modeling and a GAN (Generative Adversarial Network), the high-security identity authentication of a complex imitation is realized. The method comprises the following steps: carrying out effective identification of a high-biomimetic material, carrying out physical modeling to analyze the absorption characteristics of palm veins in a hyperspectral range, such as the difference between oxyhemoglobin and oxyhemoglobin and periodic spectrum micro-interference caused by heart rate, and providing living body evidence based on physiological dynamics; meanwhile, a high-simulation template sample generated by the GAN is used for training a discriminator, the insight ability of the system to a template means is further enhanced, and compared with single traditional texture or static signal detection, the system combines physical characteristics with deep learning, and the confidence coefficient of in-vivo detection reaches up to 99.99%.

To provide a color and shape change monitoring system capable of accurately monitoring the color and shape change of a human body caused by a blood flow change.SOLUTION: The image processing apparatus includes a three dimensional point cloud data acquisition unit configured to acquire three dimensional point cloud data of a measurement target portion of a human body, a color data acquisition unit configured to acquire color data of the measurement target portion, a color-shape-data generation unit configured to generate color-shape data of the measurement target portion in which the color data is associated with the three dimensional point cloud data, and a pigment component separation unit configured to separate the color-shape data into a hemoglobin pigment component, a melanin pigment component, and a shade component.SELECTED DRAWING: Figure 1

The invention discloses a split-type glycosylated hemoglobin analysis device, and relates to the field, the split-type glycosylated hemoglobin analysis device comprises a host and a split-type isolation cover, the top of the host is provided with a modular analysis part, and the upper edge of the modular analysis part is provided with four modular assembly ports; a sample tube, a first analysis module, a second analysis module and a cleaning module are detachably assembled in the four modular assembly ports respectively, the split type isolation hood is detachably assembled above the main machine, and a control part and a sampling device are mounted at the positions, above the modular analysis part, in the split type isolation hood; the control part can control the sampling device to respectively move to a first position, a second position, a third position and a fourth position. A split modular mounting structure is adopted, and the sample tube, the first analysis module, the second analysis module and the cleaning module in the device can be taken out from modular assembly ports in the modular analysis part, so that the modules are more convenient to replace, clean and disinfect.

This disclosure relates to a method and device for determining the hemoglobin level of a mammal. The device includes several light-emitting diodes, one or more sensors, and a processor.

The application discloses an imaging method for fusing photon weight and diffuse light brain tissue blood oxygen concentration change quantity and related products, and relates to the technical field of biological tissue blood oxygen imaging. The method comprises the following steps: acquiring experimental data obtained by irradiating a measured tissue with light sources of two wavelengths; performing the following calculation on the experimental data corresponding to each wavelength of the light source: calculating the average photon transmission path of the kth light probe combination in the ith voxel unit by using a formula; calculating the photon weight of the kth light probe combination in the ith voxel unit by using a formula; calculating the change quantity of the tissue absorption coefficient of the ith voxel unit by using a formula; and finally calculating the change quantity of the concentrations of oxyhemoglobin and deoxyhemoglobin by using the calculation data obtained by the two wavelengths. The application proposes a method for fusing photon weight, and by means of weight calculation, the accurate brain tissue blood oxygen concentration change quantity can be obtained by using a small amount of S-D combination photon signals.

1. The name of the design product: blood analyzer (SZH-MF03A). 2. The use of the design product: for testing the concentration of blood glucose, uric acid, hemoglobin in blood samples. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

The invention relates to the technical field of blood detection, and particularly discloses a spectrum detection method, system, device, equipment and medium for detecting the free hemoglobin content of a plasma braid, and the method comprises the following steps: taking out a to-be-detected sample of the plasma braid to obtain an original optical measurement object to obtain the to-be-detected sample; performing multi-wavelength alternate irradiation on the to-be-detected sample and collecting continuous time sequence photoelectric response to obtain an original time sequence signal set; obtaining an absorbance set; a normalized absorption characteristic subjected to scattering and temperature dual compensation is obtained; obtaining an initial free hemoglobin concentration estimated value; the final free hemoglobin concentration and a judgment result are obtained; by directly detecting the separated plasma tube braid, the sealing performance and safety of the main blood bag are not influenced at all, and the pollution risk caused by puncture sampling is thoroughly avoided. The method is objective and accurate, results are quantified, manual subjective errors are thoroughly eliminated by adopting a spectral analysis technology, and particularly, judgment on critical value samples is extremely accurate.

A non-invasive biosignal measurement device based on skin effect removal, includes: a signal measurement instrument measuring a PPG signal of a measurement subject in contact with the skin on one side of a specific body part of the measurement subject; a signal reception unit receiving the PPG signal from the signal measurement instrument; and a ratio value calculation unit removing noise due to a skin effect from the PPG signal, and then calculating ratio values at different wavelengths for measuring a biosignal including blood sugar and glycated hemoglobin of the measurement subject. The signal measurement instrument includes a first sensor module including an optical barrier and a second sensor module for removing the skin effect.

The application provides a molecular marker related to immune traits of Lake sheep, a detection method and application thereof. Through PCR amplification and sequence analysis of a PD-L1 gene of the Lake sheep, a G / A polymorphic site at the 135th position of the amplified fragment is found, further detection of the polymorphic site of 898 Lake sheep is carried out by using KASPar primers, a least square model is established, and correlation analysis of the genotype and growth traits is carried out, and finally it is determined that the amplified PD-L1 gene fragment can be used as a molecular marker of immune traits related to the total number of red blood cells and the average concentration of hemoglobin of red blood cells of the Lake sheep. Through detection of the molecular marker, the application can be used for disease-resistant breeding of the Lake sheep, so as to guarantee the health of the Lake sheep and help to increase economic benefits.

In at least one embodiment, a hemoglobin measuring device may include a plurality of sensors, a display configured to present information, and a computing device in communication with the sensors and display and having a processor and a memory storing instructions executable by the processor. The instructions may include instructions to receive, from the sensors, measurements of one or more forms of glycated hemoglobin in a blood samples, determine a total fetal hemoglobin value in the blood sample by performing a peak area summation of all forms of fetal hemoglobin, subtract the total fetal hemoglobin value from 100 to derive a total adult hemoglobin value, determine a glycated fetal hemoglobin value, compare the glycated fetal hemoglobin value to a reference range to obtain a comparison, determine a baseline glucose control value based on the comparison, and output the baseline glucose control value and the comparison to a display for medical evaluation.

1. The name of the design product: blood analyzer (SZH-MF01A). 2. The use of the design product: for testing the concentration of blood glucose, uric acid, hemoglobin in blood samples. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

The invention discloses an image processing method and device for judging suspension red blood cell hemolysis. The method comprises the following steps: acquiring a blood image set; the blood image set comprises a plurality of blood images and corresponding label information; acquiring a blood parameter information set; the blood parameter information set comprises a plurality of blood parameters and corresponding label information; the blood parameters comprise hemoglobin concentration, reticulocyte concentration, indirect bilirubin concentration, lactic dehydrogenase concentration and globin concentration; utilizing the blood image set and the blood parameter information set to construct a blood hemolysis composite detection model; based on the blood hemolysis composite detection model, processing the collected blood image and blood parameters to obtain hemolysis detection result information; the hemolysis detection result information is used for representing erythrocyte hemolysis information of the blood corresponding to the collected blood image and blood parameters.

Absorbance is used to measure hemoglobin and bilirubin parameters in whole blood samples.SOLUTION: System 10 includes an optical-sample module 20, a spectrometer module 100, a fiber-optic assembly 90 that optically connects optical-sample module 20 to spectrometer module 100, and a processor module 150. The optical-sample module 20 includes a light-emitting module having an LED light source, a cuvette assembly, and a calibration-light module. Processor module 150 receives and processes electrical signals from spectrometer module 100 and converts the electrical signals into output signals usable to display and report hemoglobin parameter values and / or total bilirubin parameter values for a whole blood sample.SELECTED DRAWING: Figure 1

The utility model discloses a rapid hemoglobin detection device, which relates to the technical field of clinical medicine, and comprises a device shell, the upper end of the device shell is provided with a display screen and a control button, and the upper end of the device shell is provided with an inner groove; according to the rapid hemoglobin detection device, when a detection opening needs to be detected, a sliding block is moved to drive a limiting block to be separated from the interior of a limiting hole, a connecting block and a positioning block are pulled upwards, a sealing plate is opened, the detection opening is put into a reagent card for detection, then the sealing plate is closed, and the arc-shaped surface of the positioning block and the arc-shaped surface of the limiting block are extruded; the limiting block is extruded into the sliding groove, and the limiting block is inserted into the limiting hole under the elastic potential energy of the supporting spring, so that the connecting block is limited, the sealing plate is tightly closed, the detection port is prevented from being in contact with the external environment, the sealing effect is good, errors are not likely to exist in the detection process, and the accuracy of the detection structure can be ensured.

A demand-adapting and auto-regulatory ECMO system and method is disclosed that may be configured to provide complete cardiopulmonary replacement. The system and method employ a blood gas exchanger having a blood inlet, a blood outlet, a gas inlet, and a gas outlet, an oxygen sensor positioned to detect oxyhemoglobin saturation at the blood inlet, and a carbon dioxide sensor positioned to detect exhaust gas CO2 concentration at the gas outlet. A controller communicates with the oxygen sensor and the carbon dioxide sensor and controls blood flow and gas flow through the blood gas exchanger in response to a sensed oxygen level by the oxygen sensor and a sensed carbon dioxide level by the carbon dioxide sensor, in turn maintaining the sensed oxygen level and the sensed carbon dioxide level within a pre-designated range of values to maintain a patient's metabolic requirements.

This application relates to the field of medical image processing technology, specifically to a hemoglobin emphasis device and method for endoscopes. The device includes a light source unit; an imaging unit for acquiring reflected light signals from a target area under multispectral illumination and outputting a raw Bayer format image or an RGB color image; and an image processing unit for receiving and processing the output Bayer format image or RGB color image, comprising at least: a spectral reconstruction module for calculating and reconstructing a single-band image signal using a spectral reconstruction model; a hemoglobin concentration calculation module configured to calculate a relative hemoglobin concentration based on the image signal; and an image enhancement module configured to perform pixel-level gain adjustment on the raw color image or the processed image, convert it to a set color space for contrast mapping, and finally output a hemoglobin-emphasized image. The image output by this invention can significantly improve the contrast between blood vessels and surrounding tissues.

The present application belongs to the field of gas detection, and relates to a combined detection tube for detecting carbon monoxide concentration in blood. The device of the present application is composed of a sample adding tube and a detection tube. The filler section arranged in the sample adding tube can effectively destroy red blood cells to release CO gas under the action of Cr(VI) / Cr(III) redox system, and at the same time, the reducing substances such as glutathione (GSH) and ascorbic acid in blood are removed through the interference removal section, thereby significantly improving the specificity and accuracy of detection. The indicating glue section in the detection tube adopts a platinum-selenium compound and a potassium iodate system, which occurs a color reaction in the presence of CO: I2O5+5CO→I2+5CO2, and the generated iodine element presents a brown color development band, the length of which is positively correlated with the concentration of HbCO, so as to realize the visual quantitative analysis of the content of carboxyhemoglobin in blood.

1. The name of the design product: blood analyzer (SZH-MF02A). 2. The use of the design product: for testing the concentration of blood glucose, uric acid, hemoglobin in blood samples. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

This application discloses an endoscopic image processing method based on blood oxygen saturation and multi-center wavelength, relating to the field of medical image processing. The method includes acquiring a first initial image signal, a second initial image signal, a third initial image signal, and a fourth initial image signal; calculating oxyhemoglobin concentration information at a target site based on the second and third initial image signals; calculating deoxyhemoglobin concentration information at the target site based on the second and fourth initial image signals; calculating blood oxygen saturation at the target site based on the oxyhemoglobin and deoxyhemoglobin concentration information; enhancing the brightness of the second initial image signal based on the blood oxygen saturation to obtain a second enhanced image signal; and generating a target image based on the second enhanced image signal, the first initial image signal, and the third initial image signal. The target image is used to identify the bleeding location at the target site.

According to the real-time bleeding monitoring method and device based on the spectrometry, the equipment and the storage medium, the drainage container is clamped through the intelligent detection clamp, the instantaneous flow and the corresponding actual absorbance data of the drainage container under the reference wavelength and the multiple different specified wavelengths are collected in real time, and collection is convenient and fast; according to all actual absorbance data and the hemoglobin concentration quantitative analysis model, the current hemoglobin concentration is determined objectively, accurately and efficiently; according to the current hemoglobin concentration and the instantaneous flow, the hemoglobin loss rate and the total hemoglobin loss amount are determined in real time, according to the hemoglobin loss rate and the total hemoglobin loss amount, first grading early warning is carried out, and systolic pressure and heart rate are collected in real time; according to the hemoglobin loss total amount, the systolic pressure and the heart rate, the second grading early warning is carried out, and real-time precise double grading early warning is convenient for related personnel to timely and accurately evaluate the bleeding condition and take corresponding measures.

A system and method for contactless determination of pulse-transit time from a received image sequence. The method including: determining hemoglobin concentration (HC) signals over time at a first region of interest (ROI) and a second ROI, the first ROI and the second ROI forming a pair of ROIs, the second ROI located downstream from the first ROI along a common pulse wave path; determining a pulse transit time based on a time difference between peaks in the HC signals; and outputting the pulse transit time. The method can further include determining pulse wave velocity (PWV) using the determined PTT and a distance between the pair of ROIs, and outputting the determined PWV. The method can further include determining an estimate of blood pressure using the determined PWV with a trained machine learning model, and outputting the determined estimate of blood pressure.

1. The name of the design product: full-automatic glycosylated hemoglobin analyzer (P10). 2. The use of the design product: for quantitative detection of glycosylated hemoglobin in human blood samples. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

The current disclosure relates to a method for determining the presence of a specific variant of a given protein, for example hemoglobin, capable of binding an analyte, for example oxygen, in cells of a biological sample, said method comprising determining the binding affinity of said analyte to said protein in a plurality of cells, for example red blood cells within said sample. The protein can be hemoglobin, which is capable of binding to oxygen, and the presence of specific variant of hemoglobin in cells of a blood sample is determined by the oxygen binding affinity of hemoglobin in a plurality of red blood cells within said sample. The method is also used for determining the presence of one or more specific types of red blood cells in a blood sample comprising analysing a blood sample using hyperspectral imaging. The method further relates to monitoring a disease associated with the presence of a specific variant of a given protein capable of binding an analyte in cells of an individual afflicted with said disease, wherein the method comprises the step of determining the presence of said specific variant of said protein in cells of a biological sample obtained from said individual. For example, the method is used for monitoring a disease associated with the presence of a specific variant of hemoglobin in red blood cells in an individual and / or in a fetus carried by said individual, wherein the method comprises determining the oxygen binding affinity of hemoglobin in a plurality of red blood cells in a blood sample from obtained from said individual. Moreover, the method is used for monitoring a disease relating to the presence of different types of red blood cells in an individual and / or in a fetus carried by said individual, wherein the method comprises the step of determining the presence of one or more specific types of red blood cells in a blood sample obtained from said individual by analysing said blood sample using hyperspectral imaging. The disclosure also relates to a measuring instrument configured to perform measurements following the disclosed methods.

1. Name of the product in this design: Multifunctional Testing Instrument (LipidPro+). 2. Purpose of this design: It is used for the quantitative detection of blood lipids, uric acid, β-hydroxybutyric acid, and hemoglobin concentrations in fresh capillary whole blood and venous whole blood, as well as glucose concentrations in fresh capillary whole blood, venous whole blood, and arterial whole blood, in conjunction with matching test strips. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The utility model relates to the technical field of blood arsenic detection, and discloses a blood arsenic content colorimetric detection device which comprises a reaction bottle. According to the colorimetric detection device for the arsenic content in the blood, through the arrangement of the reaction bottle, the air supply pipe, the mercury bromide test paper and the colorimetric card, after blood is faded to be colorless and transparent from red by utilizing a form of proteolysis hemoglobin in the reaction bottle, tartaric acid is added into the reaction bottle; under the action of tartaric acid, colorless blood is combined with hydrogen in a reaction bottle gas production sheet to form gaseous arsenic hydride, the arsenic hydride is sprayed to mercury bromide test paper through a gas supply pipe, the mercury bromide test paper generates color spots, and the color spots are compared with the color on a colorimetric card, so that the concentration of the arsenic content in the blood is obtained. The arsenic detection kit is simple in structure, suitable for field detection and basic medical institutions, capable of detecting low-concentration arsenic and meeting clinical detection requirements, short in detection time and capable of obtaining detection results in a short time.

This blood glucose level measurement device comprises: an acquisition unit that outputs light to a living body and detects the light transmitted through the living body, thereby acquiring waveform calculation data for calculating an oxygenated hemoglobin waveform and a deoxygenated hemoglobin waveform; a phase difference calculation unit that calculates a temporal phase difference between the oxygenated hemoglobin waveform and the deoxygenated hemoglobin waveform; and a blood glucose level calculation unit that calculates the blood glucose level of the living body on the basis of the temporal phase difference. The acquisition unit is configured to be capable of executing first sampling for acquiring the waveform calculation data at a first sampling rate and second sampling for acquiring the waveform calculation data at a second sampling rate higher than the first sampling rate.

A method for detecting a single layer of red blood cells (RBCs) in a blood smear or a small section of a blood smear that is suitable for diagnosis. The method comprises: determining the coverage of RBCs in a blood smear; determining the hemoglobin distribution; determining the presence of non-RBC cells and / or abnormal RBCs; and assigning a label of diagnostic usability to the blood smear or a small section of a blood smear.

A non-invasive hemoglobin monitoring device comprises processing circuitry coupled to an infrared receiver and a tactile button. The processing circuitry may be configured to detect a finger positioned in a finger placement area based on activation of the tactile button, acquire multiple sensor readings from the infrared receiver as the finger is positioned, calculate an average value from the multiple sensor readings, and determine a hemoglobin concentration based on the average value. A display screen coupled to the processing circuitry may display the hemoglobin concentration. The device may provide accurate hemoglobin measurements without requiring invasive blood sampling procedures, utilizing optical sensing technology and tactile feedback mechanisms to ensure proper finger positioning during measurement operations.

The invention relates to an automatic check method of glycosylated hemoglobin, a sample analysis device and a sample analysis system.The method comprises the steps that basic information of a detected person is obtained, and a detection value related to blood sugar and a detection value related to red blood cells of the detected person are obtained; according to the basic information of the detected person, the detection value related to the blood sugar and the detection value related to the red blood cells, calculating an estimated value of glycosylated hemoglobin of the detected person; and automatically checking the detection value of the glycosylated hemoglobin of the detected person according to the estimated value of the glycosylated hemoglobin of the detected person. The invention provides an automatic auditing scheme for glycosylated hemoglobin, the workload of auditing personnel can be reduced, and the auditing personnel can concentrate on auditing a small part of detection values of glycosylated hemoglobin which does not pass automatic auditing and is suspected to have problems.