Split type glycosylated hemoglobin analysis device

Abstract

The invention discloses a split-type glycosylated hemoglobin analysis device, and relates to the field, the split-type glycosylated hemoglobin analysis device comprises a host and a split-type isolation cover, the top of the host is provided with a modular analysis part, and the upper edge of the modular analysis part is provided with four modular assembly ports; a sample tube, a first analysis module, a second analysis module and a cleaning module are detachably assembled in the four modular assembly ports respectively, the split type isolation hood is detachably assembled above the main machine, and a control part and a sampling device are mounted at the positions, above the modular analysis part, in the split type isolation hood; the control part can control the sampling device to respectively move to a first position, a second position, a third position and a fourth position. A split modular mounting structure is adopted, and the sample tube, the first analysis module, the second analysis module and the cleaning module in the device can be taken out from modular assembly ports in the modular analysis part, so that the modules are more convenient to replace, clean and disinfect.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of glycated hemoglobin analysis, in particular to a split type glycated hemoglobin analysis device. BACKGROUND

[0002] It is known that glycated hemoglobin (HbA1c) is a key indicator for diabetes diagnosis and blood glucose control level monitoring, and its accuracy, efficiency and convenience are of great significance for clinical diagnosis and treatment. At present, the glycated hemoglobin analysis devices widely used in clinical laboratories are mostly based on high performance liquid chromatography or liquid chromatography principles.

[0003] The existing glycated hemoglobin analysis device usually adopts an integrated design, and its core analysis unit is a large and precise sample disc or turntable structure. The turntable rotates periodically and in multiple steps under the drive of the control system. The analysis process of a single sample, including sample and lysing agent mixing, reaction liquid heating incubation, and final spectrum data reading, can only be completed step by step by rotating the sample disc to different fixed workstations (such as sample needle, mixer, heater, colorimetric cup / flow cell and optical detection unit). This "sample moves, module is static" working mode leads to a complex analysis process and a long cycle, which limits the further improvement of the device throughput. In addition, this integrated design has significant maintenance drawbacks. First, the internal structure of the device is compact, and the pipeline connection between the modules is complex, which leads to a very complicated internal cleaning and disinfection program, and there is a high risk of biological cross-contamination. When a functional module (such as a heater, flow cell or sealing ring) fails or needs regular maintenance, a professional engineer often needs to disassemble it on site, and even the entire device needs to be returned to the factory for repair, which is time-consuming and laborious and has high maintenance costs. SUMMARY

[0004] (I) Invention purpose Therefore, the purpose of the present application is to provide a split type glycated hemoglobin analysis device, which adopts a split type modular installation structure as a whole, i.e. the split type isolation cover in the device can be removed, and the sample tube, the first analysis module, the second analysis module and the cleaning module in the device can be taken out from the modular assembly opening on the modular analysis part, so that the replacement, cleaning and disinfection of each module are more convenient.

[0005] (II) Technical solutions In order to achieve the above technical purpose, the application provides a split type glycated hemoglobin analysis device, which comprises a main machine and a split type isolation cover, a modular analysis part is installed on the top of the main machine, four modular assembly openings are arranged at the upper edge position of the modular analysis part, a sample tube, a first analysis module, a second analysis module and a cleaning module are respectively detachably assembled in the four modular assembly openings, the split type isolation cover is detachably assembled above the main machine, a control part and a sampling device are installed at the upper position of the modular analysis part in the split type isolation cover, the control part can control the sampling device to move to a first position, a second position, a third position and a fourth position respectively, wherein the first position, the second position, the third position and the fourth position correspond to the upper central positions of the sample tube, the first analysis module, the second analysis module and the cleaning module respectively.

[0006] As a further description of the above technical scheme: a lifting support is arranged inside the lower part of the modular assembly opening in which the sample tube is installed, the bottom of the sample tube is inserted into the lifting support, and a cylinder for controlling the lifting of the lifting support is arranged at the lower part of the lifting support in the inside of the modular analysis part, a top disc is arranged above the inside of the modular assembly opening in which the sample tube is installed, a through hole is formed in the center of the top disc, when the sample tube is installed, the bottom of the sample tube can be inserted into the lifting support, so that the stability of the sample tube can be improved, the cylinder is arranged to make the lifting support push the sample tube upwards, and the top disc can realize clamping structure of the sample tube, so as to ensure that the stability of the sample tube is higher during sampling, and the through hole is used for sampling.

[0007] As a further description of the above technical scheme: the bottom of the top disc is provided with a contact surface, the contact surface adopts an arc surface which is matched with the upper part of the body of the sample tube, when the upper part of the sample tube is pressed to the bottom surface position of the top disc, the upper part of the body of the sample tube is completely matched with the contact surface, so that the stability of the sample tube is higher.

[0008] As a further description of the above technical scheme: the edge of the modular assembly opening in which the sample tube is installed is also provided with a clearance, and the edge of the clearance adopts a circular arc structure.

[0009] As a further description of the above technical scheme: guide strips are installed on the side surfaces of the first analysis module and the second analysis module along the radial direction of the modular analysis part, guide grooves matched with the guide strips are formed in the inner walls of the modular assembly openings in which the first analysis module and the second analysis module are installed, when the first analysis module and the second analysis module are installed in the inside of the modular assembly opening, the guide strips are inserted into the guide grooves, when the first analysis module and the second analysis module are assembled, the alignment of the guide strips and the guide grooves makes the movement of the first analysis module and the second analysis module more stable and the alignment more accurate.

[0010] As a further description of the above technical solution: a locking plate that can overlap with each other is provided on the surface of the modular analysis part corresponding to the positions of the first analysis module and the second analysis module below the front surface of the first analysis module and the second analysis module. Based on this, when the first analysis module and the second analysis module are assembled in place, the locking plate corresponding to the front surface of the first analysis module and the second analysis module overlaps with the locking plate on the surface of the modular analysis part.

[0011] As a further description of the above technical solution: the control unit includes a suspension, a motor, and a kit, wherein the suspension is fixedly installed inside the upper part of the split-type isolation cover, the suspension adopts a U-shaped structure, and a rotating shaft is rotatably installed at the bottom of the suspension; the motor is fixedly installed between the two vertical ends of the suspension, and the output shaft of the motor is connected to the rotating shaft; the kit is connected to one side of the modular assembly port through a connecting rod; the sampling device is detachably inserted into the kit; when the motor is running, it can drive the kit to rotate through the connecting rod, thereby driving the sampling device to rotate, enabling it to switch between the first position, the second position, the third position, and the fourth position.

[0012] As a further description of the above technical solution: the sampling device includes a sleeve and a needle body, wherein the sleeve adopts a cylindrical structure closed at one end, a first cylinder is installed at the closed end of the sleeve, a movable sleeve is installed inside the sleeve, the movable sleeve adopts a hollow structure open at one end, the piston rod of the first cylinder extends into the sleeve and is connected to the movable sleeve, a piston is provided inside the needle body, a needle tip is provided at the front end of the needle body, the end of the needle body is fixed on the movable sleeve, a second cylinder is installed at the end of the needle body inside the movable sleeve, the piston rod of the second cylinder is inserted into the needle body and connected to the piston, when the first cylinder runs, it can push the entire needle body to move up and down, realizing the insertion and withdrawal of the needle tip for sampling, when the second cylinder runs, it can drive the piston inside the needle body to move, thereby realizing sample extraction and sample ejection.

[0013] As a further description of the above technical solution: a threaded structure is provided on the lower part of the outer surface of the sleeve, and the inner wall of the kit has an internal threaded structure that matches the threaded structure on the surface of the sleeve, so that the sleeve can be screwed into the kit. Specifically, a limiting ring plate is provided on the outer surface of the sleeve, and the threaded structure on the surface of the sleeve extends to the lower part of the limiting ring plate, so that the sleeve stops when it is inserted into the limiting ring plate, thus ensuring the accurate installation position of the sampling device.

[0014] As a further description of the above technical solution: the top of the host is provided with a frame, the split isolation cover is inserted into the inner side of the frame and locked by installing pins on both sides of the frame, the surface of the split isolation cover is provided with multiple observation windows for observing the internal state of the split isolation cover, and the perimeter of the split isolation cover is provided with cover doors at the corresponding positions of the modular assembly port.

[0015] In the above technical solution, the present invention provides a split-type glycated hemoglobin analysis device. The device adopts a split-type modular installation structure, that is, the split-type isolation cover in the device can be removed, and the sample tube, the first analysis module, the second analysis module, and the cleaning module in the device can all be taken out from the modular assembly port on the modular analysis section. Therefore, it is more convenient to replace, clean and disinfect each module. Furthermore, through the design of each structure in the device, each module and structure is stable and convenient during assembly and disassembly. The first and second analysis modules in this device both adopt an integrated structure, meaning that each module can independently perform sample mixing, heating, and optical data reading. Compared to the traditional method of rotating the sample tray multiple times for heating and reading, this simplifies the entire analysis process, resulting in higher analysis efficiency and a relatively lower overall cost. Attached Figure Description

[0016] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on the provided drawings without creative effort.

[0017] Figure 1 A schematic diagram of the overall structure of a split-type glycated hemoglobin analysis device provided by the present invention; Figure 2 Another structural schematic diagram of a split-type glycated hemoglobin analysis device provided by the present invention; Figure 3 A schematic diagram of the internal structure of a split-type glycated hemoglobin analysis device provided by the present invention; Figure 4 This invention provides a schematic diagram of the control unit structure in a split-type glycated hemoglobin analysis device. Figure 5 This is a schematic diagram of the sampling device structure in a split-type glycated hemoglobin analysis device provided by the present invention; Figure 6 A schematic diagram of the modular analysis unit installation structure in a split-type glycated hemoglobin analysis device provided by the present invention; Figure 7 This is a schematic diagram of the modular analysis unit in a split-type glycated hemoglobin analysis device provided by the present invention from another perspective. Figure 8 This is a schematic diagram of the structure of the first analysis module in the modular analysis section of a split-type glycated hemoglobin analysis device provided by the present invention when the module is removed. Figure 9 This is a schematic diagram of the sample tube being removed from a split-type glycated hemoglobin analysis device provided by the present invention. Figure 10 This is a schematic diagram of the top plate structure in a split-type glycated hemoglobin analysis device provided by the present invention.

[0018] Figure Descriptions: 1. Main unit; 10. Power cord; 11. Control panel; 12. Display panel; 13. Enclosure; 2. Split-type isolation cover; 21. Observation window; 22. Cover door; 3. Modular analysis unit; 30. Modular assembly port; 31. Clearance port; 32. Lifting support; 33. Top plate; 330. Through hole; 331. Contact surface; 34. Guide groove; 4. Control unit; 40. Suspension; 41. Motor; 42. Rotating shaft; 43. Connecting rod; 44. Kit; 5. Sampling device; 50. Sleeve; 51. First cylinder; 52. Needle body; 53. Second cylinder; 54. Needle tip; 6. First analysis module; 60. Guide strip; 61. Locking plate; 7. Second analysis module; 8. Cleaning module; 9. Sample tube. Detailed Implementation

[0019] The following description is exemplary in nature and is not intended to limit the scope, application, or use of this disclosure. It should be understood that in all these figures, the same or similar reference numerals indicate the same or similar parts and features. The figures are merely schematic representations of the concept and principles of embodiments of this disclosure and do not necessarily show the specific dimensions and scale of the various embodiments of this disclosure. Certain details or structures of embodiments of this disclosure may be exaggerated in particular portions of certain figures.

[0020] like Figures 1-10As shown: This embodiment provides a technical solution: a split-type glycated hemoglobin analysis device, including a main unit 1 and a split-type isolation cover 2. A modular analysis unit 3 is installed on the top of the main unit 1. Four modular assembly ports 30 are provided at the upper edge of the modular analysis unit 3. A sample tube 9, a first analysis module 6, a second analysis module 7, and a cleaning module 8 are detachably assembled in the four modular assembly ports 30 respectively. The split-type isolation cover 2 is detachably assembled on the top of the main unit 1. A control unit 4 and a sampling device 5 are installed inside the split-type isolation cover 2 at the position above the modular analysis unit 3. The control unit 4 can control the sampling device 5 to move to the first position, the second position, the third position, and the fourth position respectively. The first position, the second position, the third position, and the fourth position correspond to the upper center position of the sample tube 9, the first analysis module 6, the second analysis module 7, and the cleaning module 8 respectively. Working principle: When the device is started, the control unit 4 first controls the sampling device 5 to move to the first position, extracting a preset volume of whole blood sample from the sample tube 9 containing the blood sample. Then, it moves to the second position, injecting the extracted whole blood sample into the first analysis module 6 containing a hemolytic reagent. After the sample and reagent are thoroughly mixed in the first analysis module 6, the solution is preheated by the first analysis module 6. After preheating, the detector inside the first analysis module 6 reads the absorbance value of the solution at a specified wavelength. Simultaneously, the sampling device 5 moves to the fourth position, and the sampling needle is cleaned by the cleaning module 8. After completion, the sampling device 5 moves to the second position again, extracts a preset volume of solution from the first analysis module 6, and then moves to the third position, injecting the extracted solution into the second analysis module 7. The heating device inside the second analysis module 7 heats the solution to 37°C and maintains it for five minutes, allowing it to react with the anti-HbA1c antibody reagent inside the second analysis module 7. The detector in the second analysis module 7 reads the absorbance value of the final solution. Based on the absorbance values ​​read by the detectors in the first analysis module 6 and the second analysis module 7, the percentage result of HbA1c in the blood sample can be calculated.

[0021] It should also be noted that both the second analysis module 7 and the first analysis module 6 are equipped with heating devices and optical detection units. The heating devices can be electric heaters and temperature sensors. The electric heaters can heat the solutions inside the second analysis module 7 and the first analysis module 6. The temperature sensors can sense the solution temperature in real time. The detectors in the optical detection units can read the absorbance values ​​of the solution at a specified wavelength.

[0022] In summary, the device adopts a modular installation structure, meaning the separate isolation cover 2 can be removed, and the sample tube 9, first analysis module 6, second analysis module 7, and cleaning module 8 can all be taken out from the modular assembly port 30 on the modular analysis section 3. Therefore, it is more convenient to replace, clean, and disinfect each module. Furthermore, the first analysis module 6 and the second analysis module 7 adopt an integrated structure, meaning that each of the first analysis module 6 and the second analysis module 7 can independently perform sample mixing, heating, and optical path data reading. Compared with the traditional sample tray that requires multiple rotations for heating and reading, the entire analysis process is simplified, resulting in higher analysis efficiency and a relatively lower overall equipment cost.

[0023] Additionally, it should be noted that the front surface of the main unit 1 is equipped with a display panel 12 and a control panel 11, and the side of the main unit 1 is equipped with a power cord 10.

[0024] Specifically, such as Figures 1-5 As shown, in order to keep the sample tube 9 stable during sampling after installation, in this embodiment, a lifting support 32 is provided at the lower part of the modular assembly port 30 where the sample tube 9 is installed. The bottom of the sample tube 9 is inserted into the lifting support 32. A cylinder for controlling the lifting support 32 is provided at the lower part of the modular analysis unit 3. A top plate 33 is provided at the upper part of the modular assembly port 30 where the sample tube 9 is installed. A through hole 330 is opened in the center of the top plate 33. Based on this, when installing the sample tube 9, the bottom of the sample tube 9 can be inserted into the lifting support 32, which can improve the stability of the sample tube 9. The cylinder allows the lifting support 32 to push the sample tube 9 up. Together with the top plate 33, it can achieve a clamping structure for the sample tube 9, thereby ensuring higher stability of the sample tube 9 during sampling. The through hole 330 is used for sampling.

[0025] Specifically, such as Figure 10 As shown, in order to further improve the stability of the sample tube 9 during sampling, in this embodiment, the bottom of the top plate 33 is provided with a contact surface 331. The contact surface 331 adopts an arc-shaped surface that fits the upper part of the sample tube 9. Based on this, when the upper part of the sample tube 9 is pressed to the bottom surface of the top plate 33, the upper part of the sample tube 9 is completely in contact with the contact surface 331, so the stability of the sample tube 9 is higher.

[0026] Specifically, such as Figures 5-10 As shown, in order to facilitate the installation and disassembly of the sample tube 9, in this embodiment, the edge of the modular assembly port 30 on which the sample tube 9 is installed is also provided with a clearance port 31, and the edge of the clearance port 31 adopts an arc-shaped structure.

[0027] Specifically, such as Figures 5-10As shown, in order to facilitate the alignment of the first analysis module 6 and the second analysis module 7 during assembly, in this embodiment, guide strips 60 are installed on the sides of the first analysis module 6 and the second analysis module 7 along the radial direction of the modular analysis section 3. The inner wall of the modular assembly port 30 on which the first analysis module 6 and the second analysis module 7 are installed is provided with guide grooves 34 that are adapted to the guide strips 60. When the first analysis module 6 and the second analysis module 7 are installed inside the modular assembly port 30, the guide strips 60 are inserted into the guide grooves 34. Based on this, when the first analysis module 6 and the second analysis module 7 are assembled, the alignment of the guide strips 60 and the guide grooves 34 makes the movement of the first analysis module 6 and the second analysis module 7 smoother and the alignment more accurate.

[0028] Specifically, such as Figures 5-10 As shown, in order to lock the first analysis module 6 and the second analysis module 7, in this embodiment, a locking plate 61 that can overlap with each other is provided on the surface of the modular analysis part 3 corresponding to the positions of the first analysis module 6 and the second analysis module 7 below the front surfaces of the first analysis module 6 and the second analysis module 7. Based on this, when the first analysis module 6 and the second analysis module 7 are assembled in place, the front surfaces of the first analysis module 6 and the second analysis module 7 overlap with the locking plate 61 corresponding to the surface of the modular analysis part 3. Specifically, a pin hole is opened at the center of the locking plate 61, and the first analysis module 6 and the second analysis module 7 can be locked by inserting a locking pin into the pin hole.

[0029] Specifically, such as Figures 3-5 As shown, in order to control the sampling device 5, in this embodiment, the control unit 4 includes a suspension 40, a motor 41, and a kit 44. The suspension 40 is fixedly installed inside the upper part of the split isolation cover 2. The suspension 40 adopts a U-shaped structure, and a rotating shaft 42 is rotatably installed at the bottom of the suspension 40. The motor 41 is fixedly installed between the two vertical ends of the suspension 40. The output shaft of the motor 41 is connected to the rotating shaft 42. The kit 44 is connected to one side of the modular assembly port 30 through a connecting rod 43. The sampling device 5 is detachably inserted into the kit 44. Based on this, when the motor 41 runs, it can drive the kit 44 to rotate through the connecting rod 43, thereby driving the sampling device 5 to rotate, so that it can switch between the first position, the second position, the third position, and the fourth position.

[0030] Specifically, such as Figures 4-5As shown, in order to extract samples, in this embodiment, the sampling device 5 includes a sleeve 50 and a needle body 52. ​​The sleeve 50 adopts a cylindrical structure closed at one end, and a first cylinder 51 is installed at the closed end of the sleeve 50. A movable sleeve 500 is installed inside the sleeve 50. The movable sleeve 500 adopts a hollow structure open at one end. The piston rod of the first cylinder 51 extends into the sleeve 50 and connects to the movable sleeve 500. A piston is provided inside the needle body 52, and a needle is provided at the front end of the needle body 52. The head 54 and the end of the needle body 52 are fixed to the movable sleeve 500. The end of the needle body 52 is located inside the movable sleeve 500 and a second cylinder 53 is installed. The piston rod of the second cylinder 53 is inserted into the needle body 52 and connected to the piston. Based on this, when the first cylinder 51 runs, it can push the needle body 52 to move up and down as a whole, realizing the insertion and withdrawal of the needle head 54 for sampling. When the second cylinder 53 runs, it can drive the piston inside the needle body 52 to move, thereby realizing sample extraction and sample ejection.

[0031] Specifically, such as Figure 5 As shown, in order to enable the sampling device 5 to be disassembled and replaced periodically, in this embodiment, a threaded structure is provided on the lower surface of the outer surface of the sleeve 50, and the inner wall of the kit 44 has an internal threaded structure that matches the threaded structure on the surface of the sleeve 50, so that the sleeve 50 can be screwed into the kit 44. Specifically, a limiting ring plate is provided on the outer surface of the sleeve 50, and the threaded structure on the surface of the sleeve 50 extends to the lower part of the limiting ring plate, so that the sleeve 50 stops when it is inserted into the limiting ring plate. This can ensure that the installation position of the sampling device 5 is accurate.

[0032] Specifically, such as Figures 1-3 As shown, in order to make the split isolation cover 2 detachable and facilitate regular maintenance and disinfection of the equipment interior, in this embodiment, the top of the host 1 is provided with a frame 13, the split isolation cover 2 is inserted into the inner side of the frame 13 and locked by installing pins on both sides of the frame 13. The surface of the split isolation cover 2 is provided with multiple observation windows 21 for observing the internal state of the split isolation cover 2, and the perimeter of the split isolation cover 2 is provided with cover doors 22 at the corresponding positions of the modular assembly port 30.

[0033] The exemplary implementation of the solution proposed in this disclosure has been described in detail above with reference to preferred embodiments. However, those skilled in the art will understand that various modifications and alterations can be made to the above specific embodiments without departing from the spirit of this disclosure, and various combinations can be made to the various technical features and structures proposed in this disclosure without exceeding the protection scope of this disclosure, which is determined by the appended claims.

Claims

1. A split-type glycated hemoglobin analysis device, characterized in that, It includes: The host (1) is provided with a modular analysis part (3) on the top, four module assembly openings (30) are arranged on the upper edge of the modular analysis part (3), and a sample tube (9), a first analysis module (6), a second analysis module (7) and a cleaning module (8) are detachably assembled in the four module assembly openings (30) respectively; A split isolation cover (2) is detachably assembled above the host (1), and a control part (4) and a sampling device (5) are arranged inside the split isolation cover (2) and located above the upper position of the modular analysis part (3); the control part (4) can control the sampling device (5) to move to a first position, a second position, a third position and a fourth position respectively, wherein the first position, the second position, the third position and the fourth position correspond to the upper central positions of the sample tube (9), the first analysis module (6), the second analysis module (7) and the cleaning module (8) respectively.

2. The split-type hemoglobin Aic analysis device according to claim 1, wherein A lifting support (32) is arranged inside and below the module assembly opening (30) provided with the sample tube (9), the bottom of the sample tube (9) is inserted into the lifting support (32), and a cylinder for controlling the lifting of the lifting support (32) is arranged inside and below the lifting support (32) of the modular analysis part (3); a top disc (33) is arranged inside and above the module assembly opening (30) provided with the sample tube (9), and a through hole (330) is arranged at the center of the top disc (33).

3. The split-type hemoglobin Aic analysis device according to claim 2, wherein The bottom of the top disc (33) is provided with a contact surface (331) which is an arc surface matched with the upper body of the sample tube (9).

4. The split-type hemoglobin Aic analysis device according to claim 2, wherein The edge of the module assembly opening (30) provided with the sample tube (9) is further provided with a clearance opening (31), and the edge of the clearance opening (31) is in a circular arc structure.

5. The split-type hemoglobin Aic analysis device according to claim 1, wherein Guide strips (60) are arranged on the side surfaces of the first analysis module (6) and the second analysis module (7) along the radial direction of the modular analysis part (3), guide grooves (34) matched with the guide strips (60) are arranged in the inner walls of the module assembly openings (30) provided with the first analysis module (6) and the second analysis module (7), and the guide strips (60) are inserted into the guide grooves (34) when the first analysis module (6) and the second analysis module (7) are assembled inside the module assembly openings (30).

6. The split-type hemoglobin Aic analysis device according to claim 5, wherein Locking plates (61) capable of overlapping each other are arranged on the surface of the modular analysis part (3) corresponding to the first analysis module (6) and the second analysis module (7) below the front surfaces of the first analysis module (6) and the second analysis module (7), so that the front surfaces of the first analysis module (6) and the second analysis module (7) overlap with the locking plates (61) on the surface of the modular analysis part (3) when the first analysis module (6) and the second analysis module (7) are assembled in place.

7. The split-type hemoglobin Aic analysis device according to claim 1, wherein The control part (4) comprises: Suspension (40) is fixedly installed above the inside of the split isolation cover (2), the suspension (40) adopts U-shaped structure, the bottom of the suspension (40) is rotatably installed with the rotating shaft (42); Motor (41) is fixedly installed between the two vertical ends of the suspension (40), the output shaft of the motor (41) is connected with the rotating shaft (42); Kit (44) is connected on one side of the modular assembly opening (30) through connecting rod (43), the sampling device (5) can be detachably inserted into the kit (44).

8. The split-type hemoglobin Aic analysis device according to claim 7, wherein The sampling device (5) comprises: Sleeve (50) adopts a closed cylindrical structure at one end, the closed end of the sleeve (50) is provided with a first cylinder (51), the inside of the sleeve (50) is provided with a movable sleeve (500), the movable sleeve (500) adopts a hollow structure with one end open, the piston rod of the first cylinder (51) extends into the inside of the sleeve (50) and is connected with the movable sleeve (500); Needle body (52) is provided with a piston inside, the front end of the needle body (52) is provided with a needle (54), the tail end of the needle body (52) is fixed on the movable sleeve (500), the tail end of the needle body (52) is provided with a second cylinder (53) inside the movable sleeve (500), the piston rod of the second cylinder (53) is inserted into the needle body (52) and connected with the piston.

9. The split-type hemoglobin Aic analysis device according to claim 8, wherein The outer surface of the sleeve (50) is provided with a threaded structure, the inner wall of the kit (44) has an internal thread structure matched with the surface thread structure of the sleeve (50), so that the sleeve (50) can be screwed into the kit (44).

10. The split-type hemoglobin Aic analysis device according to claim 1, wherein The top of the main machine (1) is provided with a surrounding frame (13), the split isolation cover (2) is inserted into the inside of the surrounding frame (13) and is locked by installing pins on both sides of the surrounding frame (13), the surface of the split isolation cover (2) is provided with a plurality of observation windows (21) for observing the internal state of the split isolation cover (2), the surrounding of the split isolation cover (2) is provided with cover doors (22) at the corresponding positions of the modular assembly opening (30).

Images