15 results about "Deep brain stimulation" patented technology

A stimulation electric field display method, an apparatus, an electronic device, and a storage medium. The method comprises: in response to a model display operation, determining a target object and a brain tissue image model corresponding to the target object, wherein the brain tissue image model comprises at least one electrode model for deep brain stimulation (S110); in response to an electrode configuration operation, determining electrode configuration information and stimulation parameter application information of each electrode model (S120); and in response to an electric field display operation, determining program-controlled electric field information of the at least one electrode model under the electrode configuration information and the stimulation parameter application information, and displaying the program-controlled electric field information on the displayed brain tissue image model (S130).

Techniques are disclosed for defining a homeostatic window for controlling delivery of electrical stimulation therapy to a patient. In one example, a method includes generating and delivering electrical stimulation therapy to tissue of a patient via electrodes. Further, the method includes adjusting a level of a parameter of the electrical stimulation therapy such that a signal of the patient is not less than a lower bound and not greater than an upper bound. The lower bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce one or more symptoms of a disease while the patient was receiving medication for reduction of the one or more symptoms. Further, the upper bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce the one or more symptoms when the patient was not receiving the medication.

Embodiments of an implantable system and apparatus for providing electrical and optical deep brain stimulation are disclosed. Through the biological introduction of light-responsive opsins to neurons, the system is operable to transform neurons into optogenetically programmable state and history-dependent logical transformers. Embedded processors of the system are operable to stimulate individual neurons using phase-shifted electrical and / or optical signals through a neural interface comprising a plurality of carbon nanotubes, then electrically and / or optically measure the neurons. Due to the parallelism and chemical superposition of the human brain, the implantable system is operable to establish a quantum-like processing ability using its neural interface.

The utility model discloses a kind of electromagnetic shielding's mouse brain deep electrical stimulation and collection device, including protective shell and shielding shell, protective shell bottom is equipped with opening, top is equipped with connecting port, opening is fixedly adhered with animal skull surface, electrode main body, adapter terminal wire and USB conversion interface connected in sequence are equipped in protective shell, electrode main body implants in animal brain through opening;Shielding shell is inserted with connecting port, shielding shell is inserted with connecting port in, USB interface and preamplifier are equipped in shielding shell, USB interface connects USB conversion interface, preamplifier is connected host computer by data line and passes out shielding shell.The utility model, the production and composition of electrode are modularized split, standardization production and surgical implantation process;Modularization installed USB conversion interface hardware cost is very small, improve the Omnetics interface utilization of host computer;USB conversion interface and electrode main body between using adapter terminal wire, namely soft line connection, can avoid the screw drop caused by multiple plug and unplug, prolongs the implantation time of electrode.

In some variations provided herein, the system for deep brain stimulation includes an implantable device that acquires and stores recordings of neural activity signals and applies electrical stimulation. The system also includes a personal controller device that establishes a first wireless connection to the implantable device. The personal controller device transmits power to the implantable device, and the implantable device transmits recordings of neural activity signals to the personal controller device via the first wireless connection. The system further includes a clinician programmer device that establishes a second wireless connection based on activation of the first wireless connection to receive recordings of neural activity signals from the implantable device. The clinician programmer device sets one or more stimulation parameters based on the neural activity signal recordings.

The present application relates to the field of medical equipment, and particularly to a pulse generator and a control method thereof. The pulse generator of the present application uses the same pulse output circuit to send the same pulse output signal to the deep brain stimulation circuit and the vagus nerve stimulation circuit, so that the pulse generator can send the vagus nerve stimulation electrical signal to stimulate the vagus nerve and send the deep brain stimulation electrical signal to stimulate the deep brain. Since the deep brain stimulation electrical signal and the vagus nerve stimulation electrical signal are synchronously started based on the same pulse output signal, the two can be coordinated according to certain rules to achieve better therapeutic effect.

Provided is a closed-loop neuromodulation system involving coordinated intervention of the brain, the spinal cord, and the lumbosacral region, which comprises a deep brain stimulation unit (401), a deep brain field potential sensing unit (402), a spinal cord stimulation unit (501), an evoked potential sensing unit (502), a control decision-making unit (10), a deep brain electrode (403), a spinal cord electrode (503), a lumbosacral electrode (602), a docking lead (601), a radio frequency transmission unit (20), and a wireless charging and power management unit (30). By constructing an application strategy for coordinated regulation of the brain, the spinal cord, and the lumbosacral region, only one neurostimulator needs to be implanted. It can be used alone for brain diseases or spinal cord-related diseases, and can also be used for coordinated stimulation for motor function reconstruction and recovery in paralyzed patients and patients with motor dysfunction, as well as for the treatment of urinary system complications. The whole system is modular in application, can be selectively used according to disease conditions, and has a wider application range.

Disclosed herein is a system and method for performing floating transcranial electrical stimulation in which one or more free-floating insulated wires or bundles of wires are surgically implanted in the brain. The wires have exposed electrodes at both ends and are coupled with an electrode array applied to an external surface of the skull. The single wire or a bundle of wires acts to relay an electric field generated by the electrode array to a target area deep in the brain, thereby realizing the benefits of conventional deep brain stimulation without the inherent risk of infection associated therewith.

Embodiments of an implantable system and apparatus for providing electrical and optical deep brain stimulation are disclosed. Through the biological introduction of light-responsive opsins to neurons, the system is operable to transform neurons into optogenetically programmable state and history-dependent logical transformers. Embedded processors of the system are operable to stimulate individual neurons using phase-shifted electrical and / or optical signals through a neural interface comprising a plurality of carbon nanotubes, then electrically and / or optically measure the neurons. Due to the parallelism and chemical superposition of the human brain, the implantable system is operable to establish a quantum-like processing ability using its neural interface.

In some variations provided herein, the system for deep brain stimulation includes an implantable device that acquires and stores recordings of neural activity signals and applies electrical stimulation. The system also includes a personal controller device that establishes a first wireless connection to the implantable device. The personal controller device transmits power to the implantable device, and the implantable device transmits recordings of neural activity signals to the personal controller device via the first wireless connection. The system further includes a clinician programmer device that establishes a second wireless connection based on activation of the first wireless connection to receive recordings of neural activity signals from the implantable device. The clinician programmer device sets one or more stimulation parameters based on the neural activity signal recordings.

The present disclosure discloses a device, a chip, an apparatus and a readable storage medium for closed-loop deep brain stimulation, the device comprising: a controller configured to generate a control signal for deep brain stimulation based on a preset initial signal and a brain electrical feedback signal; a waveform generation module configured to generate a stimulation waveform based on the control signal; and an operation circuit configured to perform model operation for simulating physiological characteristics of a condition based on the stimulation waveform to generate a stimulation signal for deep brain stimulation. The device according to the embodiments of the present disclosure can automatically adjust and adaptively adjust the control signal to meet the needs of individualized stimulation programs.

Methods and systems for providing stimulation to a patient's brain using one or more electrode leads implanted in the patient's brain are described. The methods and systems use evoked potentials (EPs) and other indicators of therapeutic effectiveness / side effects to provide closed-loop control of the stimulation. Some embodiments involve recording EPs and using one or more features of the EPs to model how the stimulation activates networks within the patient's brain. A control algorithm can be used to maintain the network activation within a predetermined ranges.

Provided in the present invention are a sleep state identification apparatus and an implantable closed-loop stimulation system for use in a sleep state, which are applied to the technical field of medical instruments. The apparatus comprises a processor, wherein the processor is used for preliminarily determining, on the basis of user state information and / or a clock reading, whether a user is in a sleep state, when the user is in a suspected sleep state, acquiring a local field potential (LFP) collected by an electrode and an acceleration collected by a triaxial accelerometer, on the basis of the LFP and the acceleration, re-determining whether the user is in a sleep state, and when the user is in the sleep state, determining a sleep stage on the basis of the LFP. The system comprises the sleep state identification apparatus and a controller, wherein the controller is used for performing proportional regulation and stimulation signal output by using a stimulation amplitude corresponding to the sleep stage. In the present invention, a sleep state of a user is accurately identified, stimulation parameters are intelligently regulated and stimulation signals are output, so as to realize automatic and deep brain stimulation for the user, thereby achieving personalized treatment and improving therapeutic effects.

Methods and systems are described for assisting in programming stimulation parameters for deep brain stimulation (DBS) of a subject patient. A cumulative database records a set of stimulation parameters used in a programming session for a plurality of patients and associates the set of parameters with good treatment outcomes and / or side effects. The cumulative database also includes a stimulus field model (SFM) for the set of parameters. The overlap of the SFM for the set of parameters may be associated with a therapeutic effect and used to determine a target volume and / or an avoidance volume for stimulation of the subject patient. In some embodiments, the SFMs may be weighted to de-emphasize the volume near the electrode leads.