24 results about "Spinal nerve" patented technology

The invention discloses an instrument implantation safety analysis method under regulation and control of a brain-computer interface and spinal nerve, and relates to the technical field of crossing of biomedical engineering and neural engineering. According to the model, a BCI decoding instruction and an actually-collected multi-modal physiological signal are used as input, parameter identification continuous optimization is carried out, the difference between actual spinal cord response and expected response generated by the model is calculated, a predicted value and an actual value of a coupling dynamics model are compared in real time, a risk value is dynamically calculated, once a threshold value is exceeded, risk leading factors are locked immediately, and the risk leading factors are locked immediately. According to the method, a BCI-SCN system is constructed, a high-specificity self-adaptive adjustment mechanism is triggered, it is ensured that the BCI-SCN system always works in a safe interval in a complex and changeable human nerve environment, macroscopically observed abnormal phenomena are accurately traced to specific reasons of a microscopic level, and a decision basis is provided for subsequent accurate regulation and control.

The invention relates to the technical field of medical education equipment, and discloses a spinal cord injury teaching model with sensory-motion plane visualization and voice guidance functions. Comprising a human body model body, a plurality of red light emitting diodes, a plurality of blue light emitting diodes, a plurality of micro steering engines, a key input module, a main controller, a voice synthesis module and a rechargeable power supply, when a spinal nerve segment, a body side and a muscle strength level are selected through the key input module, the main controller controls all red light-emitting diodes or blue light-emitting diodes, located on the spinal nerve segment and above the spinal nerve segment, in the selected body side to be turned on. And the control module is used for controlling the voice synthesis module to play voice contents corresponding to the selected spinal nerve segment, the selected body side and the selected muscle strength level, and driving the micro steering engine corresponding to the key movement muscle in the selected body side to rotate to a preset angle corresponding to the selected muscle strength level. The control module is used for controlling the voice synthesis module to play the voice contents corresponding to the selected spinal nerve segment, the body side and the muscle strength level.

The utility model discloses an action guiding device for spinal nerve function rehabilitation training, and belongs to the technical field of rehabilitation equipment. Comprising a supporting plate, a fixing plate, supporting rods, sliding shafts, an outer rotating sleeve and a handle, the fixing plate is vertically arranged, the supporting plate is horizontally fixed to the vertical side face of the fixing plate, the multiple supporting rods are arranged and fixed to the same horizontal plane of the supporting plate, and the sliding shafts are arranged on the side, away from the supporting rods, of the supporting plate and located on the outer side of the supporting plate. In the sliding process of the sliding shaft, the friction layer applies friction resistance to the movement of the sliding shaft, so that the force required by a user to push or pull the sliding shaft to move is increased, the muscles of the arms and the shoulders of the user are exercised, small-amplitude movement can be generated on the spine part in the exercising process, and the user can do exercise on the spine part. In addition, the proliferated muscle group can have a protection effect on the spine part, and normal recovery of the spinal nerve function can be improved.

The invention relates to the technical field of medical monitoring, and particularly discloses an AI anesthesia depth monitoring system combined with nerve stimulation, which is characterized in that standardized electrical stimulation is applied to a motor nerve pathway of a patient in a general anesthesia state, and spinal nerve electrical signals and limb movement signals induced by the standardized electrical stimulation are synchronously acquired and analyzed; performing time-frequency transformation on the neural signal to extract a dominant oscillation mode of the neural signal, and generating a neural rhythm disorder degree characteristic value by quantizing frequency jitter and amplitude attenuation; analyzing the time sequence collaboration of the motion signal and the stimulation and the motion form, and generating a motion response deviation characteristic value; fusing the two features into a two-dimensional feature vector, inputting the two-dimensional feature vector into a pre-trained anesthesia depth classification model, and directly outputting an objective anesthesia depth level; and finally, starting grading early warning according to the grade change trend and generating a monitoring report.

The invention discloses an exoskeleton robot or active power artificial limb joint angle prediction device and method. According to the method, electromyographic signals carrying neural information and inertial motion unit data carrying kinematics information are fused, information transmitted by spinal nerve and speed information in multi-modal data are utilized, and feature fusion and decoding are carried out; finally, the output is used for controlling intelligent rehabilitation equipment such as a lower limb exoskeleton robot and an active artificial limb. According to the method, the speed adaptability of the existing lower limb motion angle prediction based on the human body surface electromyogram signals is remarkably improved, and the engineering practical performance of the method is remarkably improved.

The application provides a small animal sciatic nerve magnetic resonance coil and an imaging method, and the method comprises the following steps: filling a high-concentration sugar syrup solution at the bottom of the magnetic resonance coil and performing constant temperature control; placing a small animal in a prone position in the high-concentration sugar syrup solution and discharging air in the gap between the lower limbs and below the abdomen of the small animal; after performing magnetic resonance positioning scanning to determine the main sequence scanning range, starting the main sequence scanning, suppressing the flow tissue signal through a pre-pulse combination, exciting the tissue by using a radio frequency pulse with preset parameters, acquiring echo signals by combining a fast spin echo technology and filling K space, and obtaining scanning original data; performing preprocessing on the scanning original data and accurate segmentation of the sciatic nerve and spinal nerve to obtain a segmentation result; and completing three-dimensional model reconstruction, optimization and multi-modal fusion visualization based on the segmentation result to obtain an image scanning result. The application is suitable for small animals, is accurate in imaging, can effectively suppress various kinds of artifacts, and can be widely applied to sciatic nerve imaging scenarios of small animals.

The utility model provides a spinal nerve distribution point teaching model control circuit, comprising at least one touch unit used for sensing a touch action to generate a touch signal; the control unit is used for responding to the touch signal to generate a corresponding first signal, and the first signal is at least used for recording touch position information; the signal conversion unit is used for converting the first signal into a second signal and sending the second signal to external equipment, or is used for receiving a third signal sent by the external equipment, converting the third signal into a fourth signal and then transmitting the fourth signal to the control unit; the touch unit and the signal conversion unit are both in communication connection with the control unit; by adopting the spinal nerve distribution point teaching model control circuit of the utility model, the communication function between the control unit and the external equipment is realized. The learning progress of a user can be recorded, related functions of the teaching model can be controlled through external equipment, and the defects that an existing teaching model is single in control means and cannot record the learning progress are effectively overcome.

Systems and methods for treatment of neuropathy are provided. In some examples, a method of prophylactic treatment for a disease state in a patient treatment is provided. The treatment can include (a) positioning an electromagnetic field generator adjacent to a cranial nerve; (b) directing an electromagnetic field from the electromagnetic field generator toward the cranial nerve; and repeating the treatment of steps (a) and (b) no less than one treatment per day according to a treatment plan. In some examples, a method of prophylactic treatment for a disease state in a patient treatment is provided. The treatment can include (a) positioning an electromagnetic field generator adjacent to a spinal nerve; (b) directing an electromagnetic field from the electromagnetic field generator toward the spinal nerve; and repeating the treatment of steps (a) and (b) no less than one treatment per day according to a treatment plan.

This disclosure relates to a flexible electrode for the spinal cord and a method for manufacturing the same. A flexible electrode for the spinal cord is provided, comprising: an attachment portion configured to be able to be placed on the white matter lateral to the epidural space or intradural space, and configured to acquire or apply electrical signals to the surface of the spinal cord; wherein the attachment portion of the flexible electrode includes a first insulating layer and a second insulating layer, and a conductive layer located between the first insulating layer and the second insulating layer; wherein the attachment portion of the flexible electrode further includes one or more electrode sites, each electrode site being electrically coupled to one of the conductive wires in the conductive layer, and contacting the spinal cord after implantation of the flexible electrode to acquire electrical signals from spinal nerves and transmit the acquired electrical signals through the conductive wires, or to apply electrical signals received through the conductive wires to spinal nerves.

The application discloses an implantable controllable pressure microballoon small animal spinal nerve compression device, which comprises a liquid-filled balloon, a pressing plate, an extrusion screw rod, a nut sleeve and a balloon catheter arranged in a subcutaneous blocking fabric; the pressing plate is arranged above the liquid-filled balloon; the extrusion screw rod penetrates through the skin blocking fabric from outside the skin and is arranged above the pressing plate; the nut sleeve is arranged in the skin blocking fabric and the extrusion screw rod is sleeved in the nut sleeve; the balloon catheter is communicated with the liquid-filled balloon through a liquid guide pipe; and a pressure gauge is further arranged at a liquid inlet of the balloon catheter. The device can be used for simulating spinal nerve compression injury in animal experiments, is convenient to operate, controllable in force, can detect pressure and improves the accuracy of experiments.

The utility model provides a kind of three-dimensional human body model of spinal nerve innervation body surface area, specifically related to human anatomy and neurology research technical field.Aiming at two-dimensional display mode and light interference and other problems, the utility model provides a kind of three-dimensional human body model of spinal nerve innervation body surface area, including three-dimensional human body model ontology, three-dimensional human body model ontology is divided into multiple spinal nerve innervation areas, adjacent spinal nerve innervation area is separated by light-tight partition, and each spinal nerve innervation area is provided with luminous body at its sensory key point.The device enables learners to more intuitively understand and remember the distribution and function of spinal nerves.

The invention relates to application of a Xiaji acupoint electroacupuncture in preparation of equipment for treating Parkinson's frozen gait, and belongs to the technical field of modernization of traditional Chinese medicine. A traditional Chinese medicine acupuncture technology and a modern electroacupuncture technology are combined, a new application of electroacupuncture is provided, electroacupuncture is adopted to stimulate a spine point area, an electric signal is transmitted to a center through anterior and posterior spines of spinal nerves, release of dopamine in a basal node is promoted, signal inhibition of a cortex auxiliary movement area is relieved, and the aim of treating the spines is achieved. Excitation input of anterior spinal horn motor neurons is increased, so that contraction of skeletal muscles is triggered, movement retardation and frozen gaits of Parkinson's disease patients are improved, pathological neural circuits of PD are rapidly broken, nerve functions are remodeled through long-term stimulation, and a new path is provided for drug or DBS refractory dyskinesia and frozen gaits.

This invention discloses an implantable spinal cord stimulation system and method, storage medium, and electronic device. The implantable spinal cord stimulation system includes: a pain detection module (10) for detecting user pain information; a pulse stimulation module (30) for generating pulse signals to stimulate the user's spinal nerves; and a processing module (20) for adjusting preset parameters of the pulse signals based on the pain information, thereby reducing or eliminating the user's pain. When a patient is suffering from pain, the system automatically detects pain signals and automatically adjusts the stimulation of the spinal nerves according to the pain signals, thereby quickly and effectively reducing or eliminating the patient's pain. This prevents patients with incurable neuralgia or those undergoing treatment from suffering further pain, thus reducing complications associated with neuralgia.

The invention belongs to the technical field of medical instruments, and particularly relates to electrode placement forceps for spinal nerve stimulator implantation. By introducing the design of the forceps head groove which is accurately matched with the shape of the electrode, flexible and fine operation can be carried out in a narrow operation space, and the direction and the position of the electrode can be easily adjusted; therefore, the operation difficulty is reduced, and the operation efficiency of electrode implantation is remarkably improved. Specifically, a surrounding type clamping channel is formed by the grooves, so that clamping force can be uniformly distributed on the surface of the electrode, the clamping stability and the contact area are greatly increased, and the risk of scratching or pressing damage caused by stress concentration or an uneven jaw is also avoided; the problem that in the prior art, when common instruments (such as tweezers and haemostatic forceps) are manually operated or used, the electrodes are prone to slipping and twisting is effectively solved.

The invention belongs to the technical field of medical instruments, and particularly relates to a suction type spinal nerve stimulation line pressing device. The purpose is to integrate the negative pressure suction function and the wire pressing function into a single instrument, and the smoothness, efficiency and safety of surgical operation are remarkably improved. The problems that in an existing spinal nerve stimulation electrode implantation operation, due to the fact that errhysis blocks the view field, the process is tedious, an electrode wire floats and shifts, and the risk is high due to the fact that cooperative operation of two hands or multiple instruments is needed are solved. Specifically, the line pressing device can synchronously complete visual field clearness and guide line stabilization operation in the operation environment where hematocele is removed and the visual field is limited; besides, a vent hole which can be flexibly controlled by fingers is formed in the handle, the negative pressure of the suction head can be accurately adjusted in real time, and the potential risk that sensitive nervous tissues such as spinal cords are subjected to traction injury due to the fact that suction force of a traditional aspirator is too large and cannot be adjusted is avoided.

The application discloses a pain positioning and auxiliary diagnosis method and system based on a three-dimensional human body model marking. Firstly, a three-dimensional human body model is constructed, human body parts are manually marked according to an anatomical atlas, a mapping file of a surface patch ID and a part field is generated, and 30 spinal nerve dermatomes are associated with the surface patch. The patient marks the pain area on the model, the system obtains the selected surface patch ID set, converts it into a human body part and a dermatome field by using a reverse index. Combined with the pain type and the accompanying symptoms, vector semantic retrieval and structured matching are carried out in the muscle fascia, spinal disease and fourteen meridian three major theoretical medical knowledge bases to obtain relevant medical knowledge. Finally, a diagnosis suggestion containing a suspected disease, diagnosis analysis, treatment suggestion and recommended department is generated by a large language model. The application realizes the visualization and intelligentization of outpatient pain marking, greatly shortens the positioning time of the first diagnosis, significantly improves the positioning accuracy, and then significantly improves the diagnosis and treatment efficiency.

The invention relates to the technical field of electrophysiological monitoring equipment, in particular to spinal cord and spinal nerve root function electrophysiological monitoring equipment which comprises a stimulating electrode, a programmable amplifier, a signal processing device, a stimulator, a first recording electrode and a second recording electrode. The second recording electrode is installed at the back of the center of the brain, the signal processing device judges whether signals collected by the first recording electrode are valid or not according to the state of the signals collected by the second recording electrode, and the state of the signals collected by the second recording electrode comprises whether the second recording electrode collects the signals or not or the strength of the signals collected by the second recording electrode; in the somatosensory evoked potential process, the second recording electrode is installed in front of the center of the brain, whether signals collected by the first recording electrode are effective or not can be judged according to the state of the signals collected by the second recording electrode, and therefore the final judgment result is more accurate.

This application relates to a brain-computer interface (BCI) control system and method. Its wireless power supply transmitter transmits energy through the skin at a frequency of 6.78MHz via magnetic resonance coupling to an implantable BCI controller (ICU) within the body. This allows the ICU to power an implantable brain signal acquisition unit (NRU) and an implantable spinal nerve stimulator (NSU) based on the received energy, enabling wireless power supply to implantable medical devices such as the NRU and NSU. Furthermore, the external BCI controller (ECU) and the implantable ICU communicate wirelessly for motion feedback and control, achieving a closed-loop control system of "perception-decision-feedback-adjustment," thereby improving the accuracy and adaptability of motion control.

The application discloses a columnar uniform light laser optical fiber, and the optical fiber is sequentially provided with a fiber core, a cladding layer and a sleeve layer from inside to outside, the fiber core is sleeved in the cladding layer, the sleeve layer is coated on the outer surface of the optical fiber, and N scattering monomers or N scattering birefringent points are sequentially arranged along the length direction of the fiber core at the end of the fiber core according to the design requirements of the columnar light emitting length. The scattering body particles are filled in each scattering monomer or the birefringent points are continuously written and arranged to form a scattering continuum, the cladding layer of the sleeved fiber core is butted against the scattering continuum, so that the laser treatment optical fiber realizes lateral columnar uniform light transmission in the length direction within a target set distance range. The laser optical fiber can be used for the treatment of spinal nerve injury, including intervertebral disc herniation, spinal stenosis, spondylolisthesis or traumatic fracture of each segment of cervical vertebra, thoracic vertebra, lumbar vertebra and sacral vertebra.

The invention discloses an endoscope for spinal surgery. According to the technical scheme, the endoscope is characterized by comprising a main body, the accessory connecting part is arranged on the main body and is used for connecting a functional module; one end of the sheathing canal is fixedly connected to the main body, the other end of the sheathing canal extends in the direction far away from the main body, and the end, far away from the main body, of the sheathing canal is arranged as a surgical end and extends to a surgical site; the retraction tube is arranged outside the sheath tube in a sleeving manner; the retraction assembly is arranged on the retraction tube, and the retraction assembly is used for retracting spinal nerves at the surgical end of the sheathing canal; through the arrangement of the retracting assembly, a doctor can retract spinal nerves only by operating the endoscope, so that the operation convenience is improved, and an operation can be conveniently carried out in a narrow area.

The invention relates to the technical field of nerve tract recognition, in particular to a spinal nerve tract injury assessment method based on diffusion tensor imaging. The method comprises the following steps: firstly, acquiring diffusion tensor imaging data of a spinal cord part of a patient, and constructing a fault-tolerant attraction domain based on atlas registration and morphological dilation processing so as to overcome anatomical positioning errors; determining an individualized liquefaction entropy reference according to entropy distribution of the high-diffusion sample set, and respectively constructing a conduction resistance field and a microstructure confusion field; constructing a nonlinear suppression weight by using an entropy reference to carry out weighted coupling on the resistance field, and generating a cost field for suppressing liquefaction artifacts, so that a liquefaction region is converted into a high-resistance barrier; executing anisotropic path finding based on the cost field in the fault-tolerant attraction domain to obtain an optimal transmission path; and finally, extracting multi-dimensional features of the path, and determining the functional state of the neural pathway in combination with hierarchical logic. According to the method, liquefaction artifact interference can be effectively eliminated, and adaptive and refined quantitative evaluation of the spinal nerve tract injury state is realized.

1. The name of the design product: scientific instrument (spinal nerve bifurcation model). 2. The use of the design product: for scientific instrument. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view. 5. The bottom of the design product is not easy to see or not visible when used, omit the top view.

The invention discloses a comprehensive testing device for sciatic nerve trunks, motor nerves and skeletal muscles. The comprehensive testing device comprises a specimen bearing assembly composed of PU plates, an electrophysiological signal collecting and stimulating assembly composed of acupuncture needles and miniature alligator clips, and a muscular tension testing assembly composed of a support and a tension transducer. The PU plate can fix an in-vitro spine-spinal nerve-sciatic nerve trunk-tibial nerve-gastrocnemius muscle integrated active specimen of a frog, and the acupuncture needle can puncture an adventitia and is arranged between nerve fascia membranes or puncture an adventitia of skeletal muscle and is arranged between muscular fascia membranes and is connected with a biological function data analyzer, so that electrical stimulation application and electric signal and electromyographic signal acquisition are realized, and the biological function data analyzer is connected with a biological function data analyzer. The tension transducer is connected with the specimen and synchronously collects muscular tension signals. Neural and muscle testing functions are integrated, the use amount of experimental animals is reduced, the signal-to-noise ratio of signals is increased through acupuncture needle puncture type collection, the PU plate is flexible in adaptation, the electrode distance is adjustable, and neural electrophysiological signals and muscular tension signals can be synchronously obtained.

The invention discloses application of magnolol and pharmaceutically acceptable salts thereof in inhibiting bone marrow-derived foam macrophage chronic inflammation after spinal cord injury. The invention provides application of magnolol in preparation of drugs for promoting discharge of macrophage lipid, drugs for promoting spinal cord injury repair, drugs for inhibiting lipid accumulation mediated secondary inflammation after spinal cord injury or neuroprotection drugs. The invention further provides a spinal cord injury repairing drug containing magnolol, a drug or reagent for promoting macrophage lipid excretion and a spinal cord inflammation inhibiting drug. According to the application disclosed by the invention, the magnolol is disclosed for the first time by regulating immune cell lipid excretion-inflammatory factor axis, so that the spinal nerve regeneration is obviously promoted, the nerve function is improved, the inflammatory reaction after lipid overload is relieved, and the spinal cord tissue is protected, and an innovative strategy is provided for spinal cord injury treatment. The magnolol synergistically intervenes the secondary neurodegenerative disease after spinal cord injury by improving lipid overload and immune dual pathways, and a brand new direction is provided for SCI treatment.