The invention relates to the technical field of bio-medical
engineering, and particularly relates to a
nerve stimulator. The
nerve stimulator comprises a substrate provided with a plurality of through holes, a plurality of microelectrodes arranged on the substrate through being filled in the through holes, a stimulus
chip and a shell. One side of each
microelectrode, leaks out of the substrate, serves as the stimulus part of the
microelectrode, while the other side of the
microelectrode serves as the connection part of the microelectrode. The connection parts of the microelectrodes are directly inverted and welded onto the stimulus
chip. The shell is hermetically connected with the substrate. The manufacturing method of the
nerve stimulator is composed of the
laser drilling step, the through hole plating step and other
machining steps, and the packaging manner thereof is realized through the
laser welding step. According to the technical scheme of the invention, the microelectrodes are connected with the stimulus
chip through the flip-chip
bonding process, so that the
tissue damage caused during the implantation process of the nerve stimulator can be greatly reduced. The manufacturing method is simple in process, and short in period. Based on the method, a high-density and orderly-arranged three-dimensional microelectrode array can be implemented. Meanwhile, the high-density selective stimulating and recording function can be realized. Therefore, the nerve stimulator and the manufacturing method thereof have a good application prospect.