76 results about "Nerve stimulator" patented technology

A closed-loop neuromodulation system includes at least one implantable neurostimulator configured to deliver electrical stimulation to a target nerve innervating a muscle; at least one biosignal sensor configured to detect a physiological signal associated with the target muscle, wherein the physiological signal may include an electromyographic (EMG) or electroneurographic (ENG) signal; and a controller operatively coupled to the neurostimulator and the sensor. The controller is configured to receive the physiological signal from the sensor, determine whether the signal satisfies a predefined condition indicative of weakness, strength, fatigue, muscle underactivity, or overstimulation, and, in response to detecting that the condition is satisfied, automatically adjust one or more stimulation parameters selected from amplitude, frequency, pulse width, train duration, or train count.

The invention relates to an in-vitro program controller and a control method thereof. The in-vitro program controller comprises a sensor and a processor, and the processor sets the working power of the implantable nerve stimulator, a temperature early warning value and a temperature upper limit value greater than the temperature early warning value according to the stimulation parameters; when the movement of the in-vitro program control instrument is determined at every reference time interval or according to the posture change detected by the sensor, a data reading instruction is sent to the implantable nerve stimulator so as to read the working power and temperature of the implantable nerve stimulator; increasing, decreasing or maintaining the transmitting power according to the comparison between the read working power and the set working power; according to the fact that the read temperature is larger than or equal to the set temperature early warning value and smaller than the set temperature upper limit value, the transmitting power is reduced; and sending a stimulation stop instruction when the read temperature is greater than or equal to a set temperature upper limit value. According to the invention, the working power, temperature and the like of the implantable nerve stimulator can be monitored and adjusted, so that safe treatment of a patient is ensured.

The invention discloses an ear nerve stimulator, and belongs to the technical field of biomedical engineering and nerve regulation and control. The device mainly comprises a plurality of flexible patches attached to the ear, ear electrodes arranged according to ear acupuncture points and embedded in the flexible patches, and a stimulator adopting a cross-ear design. And the flexible patch has biocompatibility and adhesion, so that comfortable and stable wearing is ensured. A control unit and a stimulation module are contained in the stimulator shell, and stimulation current parameters can be generated and accurately regulated and controlled. Through flexible fitting and precise acupoint electrode design, the defects that a traditional electrode is uncomfortable to wear, and a stimulation area is fixed and inaccurate are overcome. And the equipment is light and stable due to the ear-crossing structure. A selectable air pump and air bag mechanism further ensures the reliability of electric contact. The device can realize safe, accurate and comfortable ear vagus nerve stimulation, is suitable for treatment and rehabilitation of epilepsy, depression and other diseases, and has a wide application prospect.

A system may include a neurostimulator and a processing system configured to provide a stimulation effects map by testing stimulation parameter sets from a plurality of available stimulation parameter sets, acquiring clinical effect data indicative of a patient response to electrical energy delivered to the tissue using at least a first subset of the tested stimulation parameter sets, acquiring sensed data indicative of a sensed response to the electrical energy delivered to the tissue using at least a second subset of the tested stimulation parameter sets, and evaluating parameter sets from the plurality of untested stimulation parameter sets including for each of the evaluated parameter sets, determining an estimated response by estimating at least one of the patient response or the sensed response to the electrical energy using the acquired clinical effect data and the acquired sensed data. A stimulation parameter set may be chosen based on the map.

A neurostimulator implant is provided that includes a circuitry unit having first and second ends, a conducting side, and an opposing side. First and second electrodes are disposed on an outer surface of the circuitry unit so as to circumscribe the circuitry unit. Circuitry is disposed within the circuitry unit. An insulating member is disposed on the opposing side of the circuitry unit such that, on the opposing side, each electrode is covered by the insulating member by being sandwiched between a first side of the insulating member and the circuitry unit, such that the insulating member inhibits electrical conduction from the electrodes into tissue of a subject. A second side of the insulating member, opposite the first side, defines a generally flat side of the implant facing away from the first and the second electrodes of the circuitry unit. Other embodiments are also described.

The present application provides a neurostimulator and a receiving coil. The neurostimulator includes a receiving coil and a resonant capacitor. The receiving coil receives wireless power from the transmitting coil and has an adjustable inductance. The resonant capacitor is electrically connected to the receiving coil and forms a resonant network with an adjustable resonant frequency with the receiving coil. The resonant network adjusts the efficiency of the receiving coil in receiving wireless power through the adjustable resonant frequency. The receiving coil includes a coil body and a magnetically adjustable structure provided on the coil body. The inductance of the magnetically adjustable structure changes in response to changes in ambient temperature and is negatively correlated with the ambient temperature when the ambient temperature is higher than the rated operating temperature. When the ambient temperature rises to the over-temperature protection temperature, the inductance of the magnetically adjustable structure decreases to below the target inductance value. When the ambient temperature decreases below the rated operating temperature, the inductance of the magnetically adjustable structure remains constant at the rated inductance value.

A system may include a neurostimulator and a processing system. The neurostimulator may be configured to deliver electrical energy according to a stimulation parameter set. The stimulation parameter set may include at least one adjustable parameter. The processing system may be configured to perform a testing process to test delivering electrical energy by automatically progressing through a sequence of values for the at least one adjustable parameter in the parameter set. A first value and a second value in the sequence of values are separated by an initial parameter change interval and a second to last value and the last value in the sequence of values are separated by a final parameter change interval. Progressing through the sequence of values includes reducing the parameter change interval from the initial parameter change interval to the final parameter change interval.

A system may include a neurostimulator and a processing system, where the neuromodulator includes a directional lead. The processing system may be configured to perform a process that includes determining at least one stimulation field model (SFM) from at least a first vector that extends from a first virtual electrode on the directional lead and a second vector that extends from a second virtual electrode on the directional lead and determining a first modulation configuration corresponding to the first vector from the first virtual electrode and determining a second modulation configuration corresponding to the second vector from the second virtual electrode. The process may further include combining the first modulation configuration and the second modulation configuration into a combined modulation configuration and delivering neuromodulation via a single timing channel using the combined modulation configuration.

This invention provides a control device and system for a neurostimulator. The device includes: an operation instruction generation unit configured to acquire operations performed by a target object and generate corresponding operation signals based on the operations; a control unit configured to generate corresponding internal control commands or external stimulation state control commands based on the type of the operation signals and the operating state of the control device, and send the stimulation state control commands to the neurostimulator so that the neurostimulator can parse the operation type in the stimulation state control commands and adjust the stimulation output state in conjunction with the current stimulation output state; the control unit is further configured to acquire stimulation state control command response information fed back by the neurostimulator, the stimulation state control command response information including the adjusted stimulation output state. By implementing this invention, the state switching of the pulse output state of the neurostimulator can be realized through a single operation instruction generation unit, allowing users and patients to perform various operations on the control device by only learning a few simple operations, which is convenient and quick.

Methods and systems for testing and treating spinal cord stimulation (SCS) patients are disclosed. Patients are eventually treated with sub-perception (paresthesia free) therapy. However, supra-perception stimulation is used during “sweet spot searching” during which active electrodes are selected for the patient. This allows sweet spot searching to occur much more quickly and without the need to wash in the various electrode combinations that are tried. After selecting electrodes using supra-perception therapy, therapy is titrated to sub-perception levels using the selected electrodes. Such sub-perception therapy has been investigated using pulses at or below 10 kHz, and it has been determined that a statistically significant correlation exists between pulse width (PW) and frequency (F) in this frequency range at which SCS patients experience significant reduction in symptoms such as back pain. Beneficially, sub-perception stimulation at such low frequencies significantly lowers power consumption in the patient's neurostimulator.

An integrated switch matrix for a medical device system used for long-term monitoring of electroencephalogram (EEG) signals and mapping of the brain through cortical stimulation is configured to switch functions of various electrodes associated with the system in response to user needs. The programmable switch matrix is integrated in an EEG recording device and allows for connecting any patient electrode(s) to a ground circuit, connecting any patient electrode to a common reference, connecting a selected common reference to any or all recording device(s) in the system and, connecting any patient electrode(s) to anode and / or cathode outputs of a neurostimulator for multi-contact cortical stimulation.

This application relates to a neurostimulator, a system, a neurostimulator control method, and a storage medium. The neurostimulator includes: a storage module storing historical usage data of the neurostimulator, including historical levels of stimulation signals output by the neurostimulator during past periods of operation; a control module for determining the target level of the neurostimulator upon current power-on based on the historical usage data; and an output module for outputting a stimulation signal corresponding to the target level. This application improves ease of use while ensuring safe operation.

A system may include a neurostimulator including electrodes and a processing system, including a programming tool, configured to program the neurostimulator. The programming tool may be configured to receive both a selection of a location for a stimulation field and a selection of a shape from a plurality of shapes where the selected location and the selected shape are used to provide a stimulation field, determine a fractionalization, using the selected shape and the selected location, and program the neurostimulator with the fractionalization. The neurostimulator may be configured to stimulate at least one neural target according to the fractionalization.

Intraoral neuromodulation for the treatment clinical conditions such as, e.g., dysphagia, migraines, or speech problems can be achieved with a neuromodulation system that includes an intraoral neural stimulator, e.g., integrated into a wearable device to be positioned in the oral cavity, that is controlled based on one or more measured signals associated with an intraoral organ or nerve related to the clinical condition.

A neurostimulator (10) for applying electrical stimulation signals to a user, the neurostimulator having a first mode of operation (14) configured to be independent of a wheelchair, and a second wheelchair mode of operation (16) configured for cooperating with an electronic circuit (22) of a wheelchair (or optionally a robotic body movement device).

A system may include a neurostimulator, a feedback receiver, and a processing system. The neurostimulator may use program(s) to deliver a neurostimulation therapy to treat a patient condition and provide therapy outcomes. The feedback receiver may receive user feedback about the neurostimulation therapy, the patient condition or the therapy outcomes. The feedback receiver may include sensor(s) to sense user taps on or near the feedback receiver, a swiping motion across at least some of the feedback receiver, and / or feedback receiver movement. The processing system may test stimulation parameter sets including configure the neurostimulator to deliver the electrical energy using each of the tested stimulation parameter sets and use the user feedback to evaluate the tested stimulation parameter sets. The feedback receiver enables the patient to discreetly provide user feedback in a timely manner for a monitoring / programming application.

For non-uniform waveform patterns used to deliver neural stimulation, the system can control when to sense neural signals to appropriately control the neural stimulation. The system may include a neural sensor configured to sense neural signals, a neurostimulator configured to access the non-uniform waveform pattern and deliver neural stimulation corresponding to the non-uniform waveform pattern, and a controller. The controller may be configured to automatically allocate at least one sensing window for the non-uniform waveform pattern based on the non-uniform waveform pattern, control the neural sensor to sense neural signals during the sensing window when neural stimulation is delivered, and control the delivery of neural stimulation from the neurostimulator based on the sensed neural signals.

A system may include a neurostimulator and a processing system. The neurostimulator may be configured to provide a neurostimulation field by delivering electrical energy according to a set of values for a stimulation parameter set including adjustable parameter(s). The processing system may be configured to create a sequence of blocks to determine the neurostimulation field. The sequence may include stimulation program block(s) and ramp block(s) configured to determine a ramping sequence for changing the parameter values for the adjustable parameter(s). The ramp block(s) may be configured to determine a ramping sequence for changing the parameter values for the adjustable parameter(s), and may include a preceding ramp block and / or a subsequent ramp block. The neurostimulator is configured to provide the neurostimulation field according to the sequence of blocks.

Methods and systems for testing and treating spinal cord stimulation (SCS) patients are disclosed. Patients are eventually treated with sub-perception (paresthesia free) therapy. However, supra-perception stimulation is used during “sweet spot searching” during which active electrodes are selected for the patient. This allows sweet spot searching to occur much more quickly and without the need to wash in the various electrode combinations that are tried. After selecting electrodes using supra-perception therapy, therapy is titrated to sub-perception levels using the selected electrodes. Such sub-perception therapy has been investigated using pulses at or below 10 kHz, and it has been determined that a statistically significant correlation exists between pulse width (PW) and frequency (F) in this frequency range at which SCS patients experience significant reduction in symptoms such as back pain. Beneficially, sub-perception stimulation at such low frequencies significantly lowers power consumption in the patient's neurostimulator.

A system is provided for driving an implantable neurostimulator lead, the lead having an associated plurality of electrodes disposed in at least one array on the lead. The system comprises an implantable pulse generator (IPG), the IPG including an electrode driver, a load system for determining load requirements, an IPG power coupler, and an IPG communication system. The system also includes an external unit, which includes an external variable power generator, an external power coupler, an external communication system, and a controller for varying the power level of the variable power generator.

The present invention relates to a stimulation generator suitable for use in an implantable neurostimulator, including an injectable neurostimulator. The stimulation generator is adapted to provide a configurable stimulation signal comprising a component, such as a pulse. The stimulation generator comprises circuitry to receive and combine an amplitude control signal and a duty cycle signal to produce a preliminary output voltage signal which includes the component of the stimulation signal. It further comprises a voltage-controlled current source adapted to be driven by the preliminary output voltage signal; and a mode selector controlled by a stimulation mode signal to output the component from the preliminary output voltage signal as a current-controlled component of the stimulation signal via the voltage-controlled current source or as a voltage-controlled component of the stimulation signal.

An implantable pulse generator (IPG) including a case containing an energy storage device and one or more electrode leads. A header is coupled to the case. The header includes a cassette, an antenna coupled to the cassette and electrically coupled to the case, the case configured as a part of the antenna for receiving and transmitting electromagnetic signals, and an electrode attachment structure configured to couple with the cassette and configured to couple with the one or more electrode leads.

Apparatus for applying a treatment (216) to at least one tissue of a subject is described, the apparatus comprising a transmitting unit (210) configured to transmit a wireless power signal (214), a first implant (202a), and a second implant (202b), each of the implants being configured to receive the power signal and to apply the treatment asynchronously to each other, in response to the power signal. Other embodiments are also described.

Intraoral neuromodulation for the treatment clinical conditions such as, e.g., dysphagia, migraines, or speech problems can be achieved with a neuromodulation system that includes an intraoral neural stimulator, e.g., integrated into a wearable device to be positioned in the oral cavity, that is controlled based on one or more measured signals associated with an intraoral organ or nerve related to the clinical condition.

Spinal cord stimulation systems without paresthesia are disclosed. Ultimately, sub-perception (no paresthesia) therapy is used for patient therapy. However, super-perception stimulation is used during a "sweet spot search" to select the active electrodes for the patient. This allows the sweet spot search to occur much more quickly and does not require wash-in of the various electrode combinations tried. After the electrodes are selected using super-perception therapy, the selected electrodes are used to titrate the therapy to a sub-perception level. This sub-perception therapy has been studied using pulses at or below 10 kHz, and a statistically significant correlation has been determined between pulse width (PW) and frequency (F) within the frequency range that SCS patients experience significant reduction in symptoms such as back pain. Advantageously, sub-perception stimulation at such low frequencies significantly reduces power consumption in the patient's neurostimulator.

The invention relates to a packaging body for a medical implant, in particular a pacemaker and / or a neurostimulator, having a housing and a wire electrode connected to the housing, having a contact electrode arranged in a distal end region of the wire electrode, comprising packaging material which comprises closure means running along a sealing contour of the packaging material, wherein at least part of the packaging material and the closure means delimit a sterile and / or sterilisable interior of the packaging body, in which the implant is accommodated in a sterilely packaged state, wherein the packaging body, in particular in the interior, comprises electrically conductive contact means which are arranged such that, in the sterilely packaged state, the contact electrode of the implant, which is spaced apart from the housing of the implant by the wire electrode and is simultaneously electrically, and preferably mechanically, connected to the implant via the wire electrode, comes into contact, or can be brought into contact, with the contact means.

A neurostimulator is implantable into a body of a subject to treat an overactive bladder condition. The neurostimulator includes a pulse generator, circuitry, a lead, and a connector secured to the lead. The circuitry is disposed within the pulse generator and connected to a battery. The circuitry is configured to generate a stimulation signal with a duty cycle of between 0.1% and 2.5% and a total average current drain from the battery of between 0.1 μA and 5μA, the total average current drain including a background current, plus a stimulation current weighted by the duty cycle. The lead has an electrode assembly configured to direct the generated stimulation signal to tissue of the subject. The connector is adapted to allow the pulse generator to be detachable from and attachable to the lead.

A neural stimulation system may include at least one electrode contact and a neural stimulator configured to deliver stimulation therapy to a patient using an electrical waveform including a first phase of a first polarity and a second phase of a second polarity opposite the first polarity using the at least one electrode contact. The neural stimulator may be configured to therapeutically stimulate nervous tissue using both the first and second phases of the electrical waveform to provide stimulation therapy. The second phase removes accumulated charge caused by the first phase from the at least one electrode contact, and the first phase removes accumulated charge caused by the second phase from the at least one electrode contact. Benefits include reducing energy consumption, using a recharge pulse to activate a population of neuron devices to reduce energy consumption.

Methods and systems for testing and treating spinal cord stimulation (SCS) patients are disclosed. Patients are eventually treated with sub-perception (paresthesia free) therapy. However, supra-perception stimulation is used during "sweet spot searching" during which active electrodes are selected for the patient. This allows sweet spot searching to occur much more quickly and without the need to wash in the various electrode combinations that are tried. After selecting electrodes using supra-perception therapy, therapy is titrated to sub-perception levels using the selected electrodes. Such sub-perception therapy has been investigated using pulses at or below 10 kHz, and it has been determined that a statistically significant correlation exists between pulse width (PW) and frequency (F) in this frequency range at which SCS patients experience significant reduction in symptoms such as back pain. Beneficially, sub-perception stimulation at such low frequencies significantly lowers power consumption in the patient's neurostimulator.

A neural stimulator, suitable for implanting in a recipient, and having a flying lead with a configurable electrode. A benefit is an intra-operative ability to adjust the connection between the lead and an anatomically correct electrode, which obviates the need to manufacture multiple different configurations of implant to suit different placements of flying lead electrode.