46 results about "Nerve stimulator" patented technology

The invention relates to an in-vitro program controller and a control method thereof. The in-vitro program controller comprises a sensor and a processor, and the processor sets the working power of the implantable nerve stimulator, a temperature early warning value and a temperature upper limit value greater than the temperature early warning value according to the stimulation parameters; when the movement of the in-vitro program control instrument is determined at every reference time interval or according to the posture change detected by the sensor, a data reading instruction is sent to the implantable nerve stimulator so as to read the working power and temperature of the implantable nerve stimulator; increasing, decreasing or maintaining the transmitting power according to the comparison between the read working power and the set working power; according to the fact that the read temperature is larger than or equal to the set temperature early warning value and smaller than the set temperature upper limit value, the transmitting power is reduced; and sending a stimulation stop instruction when the read temperature is greater than or equal to a set temperature upper limit value. According to the invention, the working power, temperature and the like of the implantable nerve stimulator can be monitored and adjusted, so that safe treatment of a patient is ensured.

The invention discloses an ear nerve stimulator, and belongs to the technical field of biomedical engineering and nerve regulation and control. The device mainly comprises a plurality of flexible patches attached to the ear, ear electrodes arranged according to ear acupuncture points and embedded in the flexible patches, and a stimulator adopting a cross-ear design. And the flexible patch has biocompatibility and adhesion, so that comfortable and stable wearing is ensured. A control unit and a stimulation module are contained in the stimulator shell, and stimulation current parameters can be generated and accurately regulated and controlled. Through flexible fitting and precise acupoint electrode design, the defects that a traditional electrode is uncomfortable to wear, and a stimulation area is fixed and inaccurate are overcome. And the equipment is light and stable due to the ear-crossing structure. A selectable air pump and air bag mechanism further ensures the reliability of electric contact. The device can realize safe, accurate and comfortable ear vagus nerve stimulation, is suitable for treatment and rehabilitation of epilepsy, depression and other diseases, and has a wide application prospect.

A neurostimulator implant is provided that includes a circuitry unit having first and second ends, a conducting side, and an opposing side. First and second electrodes are disposed on an outer surface of the circuitry unit so as to circumscribe the circuitry unit. Circuitry is disposed within the circuitry unit. An insulating member is disposed on the opposing side of the circuitry unit such that, on the opposing side, each electrode is covered by the insulating member by being sandwiched between a first side of the insulating member and the circuitry unit, such that the insulating member inhibits electrical conduction from the electrodes into tissue of a subject. A second side of the insulating member, opposite the first side, defines a generally flat side of the implant facing away from the first and the second electrodes of the circuitry unit. Other embodiments are also described.

A system may include a neurostimulator and a processing system, where the neuromodulator includes a directional lead. The processing system may be configured to perform a process that includes determining at least one stimulation field model (SFM) from at least a first vector that extends from a first virtual electrode on the directional lead and a second vector that extends from a second virtual electrode on the directional lead and determining a first modulation configuration corresponding to the first vector from the first virtual electrode and determining a second modulation configuration corresponding to the second vector from the second virtual electrode. The process may further include combining the first modulation configuration and the second modulation configuration into a combined modulation configuration and delivering neuromodulation via a single timing channel using the combined modulation configuration.

This invention provides a control device and system for a neurostimulator. The device includes: an operation instruction generation unit configured to acquire operations performed by a target object and generate corresponding operation signals based on the operations; a control unit configured to generate corresponding internal control commands or external stimulation state control commands based on the type of the operation signals and the operating state of the control device, and send the stimulation state control commands to the neurostimulator so that the neurostimulator can parse the operation type in the stimulation state control commands and adjust the stimulation output state in conjunction with the current stimulation output state; the control unit is further configured to acquire stimulation state control command response information fed back by the neurostimulator, the stimulation state control command response information including the adjusted stimulation output state. By implementing this invention, the state switching of the pulse output state of the neurostimulator can be realized through a single operation instruction generation unit, allowing users and patients to perform various operations on the control device by only learning a few simple operations, which is convenient and quick.

An integrated switch matrix for a medical device system used for long-term monitoring of electroencephalogram (EEG) signals and mapping of the brain through cortical stimulation is configured to switch functions of various electrodes associated with the system in response to user needs. The programmable switch matrix is integrated in an EEG recording device and allows for connecting any patient electrode(s) to a ground circuit, connecting any patient electrode to a common reference, connecting a selected common reference to any or all recording device(s) in the system and, connecting any patient electrode(s) to anode and / or cathode outputs of a neurostimulator for multi-contact cortical stimulation.

This application relates to a neurostimulator, a system, a neurostimulator control method, and a storage medium. The neurostimulator includes: a storage module storing historical usage data of the neurostimulator, including historical levels of stimulation signals output by the neurostimulator during past periods of operation; a control module for determining the target level of the neurostimulator upon current power-on based on the historical usage data; and an output module for outputting a stimulation signal corresponding to the target level. This application improves ease of use while ensuring safe operation.

A system may include a neurostimulator including electrodes and a processing system, including a programming tool, configured to program the neurostimulator. The programming tool may be configured to receive both a selection of a location for a stimulation field and a selection of a shape from a plurality of shapes where the selected location and the selected shape are used to provide a stimulation field, determine a fractionalization, using the selected shape and the selected location, and program the neurostimulator with the fractionalization. The neurostimulator may be configured to stimulate at least one neural target according to the fractionalization.

For non-uniform waveform patterns used to deliver neural stimulation, the system can control when to sense neural signals to appropriately control the neural stimulation. The system may include a neural sensor configured to sense neural signals, a neurostimulator configured to access the non-uniform waveform pattern and deliver neural stimulation corresponding to the non-uniform waveform pattern, and a controller. The controller may be configured to automatically allocate at least one sensing window for the non-uniform waveform pattern based on the non-uniform waveform pattern, control the neural sensor to sense neural signals during the sensing window when neural stimulation is delivered, and control the delivery of neural stimulation from the neurostimulator based on the sensed neural signals.

A system may include a neurostimulator and a processing system. The neurostimulator may be configured to provide a neurostimulation field by delivering electrical energy according to a set of values for a stimulation parameter set including adjustable parameter(s). The processing system may be configured to create a sequence of blocks to determine the neurostimulation field. The sequence may include stimulation program block(s) and ramp block(s) configured to determine a ramping sequence for changing the parameter values for the adjustable parameter(s). The ramp block(s) may be configured to determine a ramping sequence for changing the parameter values for the adjustable parameter(s), and may include a preceding ramp block and / or a subsequent ramp block. The neurostimulator is configured to provide the neurostimulation field according to the sequence of blocks.

Methods and systems for testing and treating spinal cord stimulation (SCS) patients are disclosed. Patients are eventually treated with sub-perception (paresthesia free) therapy. However, supra-perception stimulation is used during “sweet spot searching” during which active electrodes are selected for the patient. This allows sweet spot searching to occur much more quickly and without the need to wash in the various electrode combinations that are tried. After selecting electrodes using supra-perception therapy, therapy is titrated to sub-perception levels using the selected electrodes. Such sub-perception therapy has been investigated using pulses at or below 10 kHz, and it has been determined that a statistically significant correlation exists between pulse width (PW) and frequency (F) in this frequency range at which SCS patients experience significant reduction in symptoms such as back pain. Beneficially, sub-perception stimulation at such low frequencies significantly lowers power consumption in the patient's neurostimulator.

A system is provided for driving an implantable neurostimulator lead, the lead having an associated plurality of electrodes disposed in at least one array on the lead. The system comprises an implantable pulse generator (IPG), the IPG including an electrode driver, a load system for determining load requirements, an IPG power coupler, and an IPG communication system. The system also includes an external unit, which includes an external variable power generator, an external power coupler, an external communication system, and a controller for varying the power level of the variable power generator.

The present invention relates to a stimulation generator suitable for use in an implantable neurostimulator, including an injectable neurostimulator. The stimulation generator is adapted to provide a configurable stimulation signal comprising a component, such as a pulse. The stimulation generator comprises circuitry to receive and combine an amplitude control signal and a duty cycle signal to produce a preliminary output voltage signal which includes the component of the stimulation signal. It further comprises a voltage-controlled current source adapted to be driven by the preliminary output voltage signal; and a mode selector controlled by a stimulation mode signal to output the component from the preliminary output voltage signal as a current-controlled component of the stimulation signal via the voltage-controlled current source or as a voltage-controlled component of the stimulation signal.

An implantable pulse generator (IPG) including a case containing an energy storage device and one or more electrode leads. A header is coupled to the case. The header includes a cassette, an antenna coupled to the cassette and electrically coupled to the case, the case configured as a part of the antenna for receiving and transmitting electromagnetic signals, and an electrode attachment structure configured to couple with the cassette and configured to couple with the one or more electrode leads.

Apparatus for applying a treatment (216) to at least one tissue of a subject is described, the apparatus comprising a transmitting unit (210) configured to transmit a wireless power signal (214), a first implant (202a), and a second implant (202b), each of the implants being configured to receive the power signal and to apply the treatment asynchronously to each other, in response to the power signal. Other embodiments are also described.

Spinal cord stimulation systems without paresthesia are disclosed. Ultimately, sub-perception (no paresthesia) therapy is used for patient therapy. However, super-perception stimulation is used during a "sweet spot search" to select the active electrodes for the patient. This allows the sweet spot search to occur much more quickly and does not require wash-in of the various electrode combinations tried. After the electrodes are selected using super-perception therapy, the selected electrodes are used to titrate the therapy to a sub-perception level. This sub-perception therapy has been studied using pulses at or below 10 kHz, and a statistically significant correlation has been determined between pulse width (PW) and frequency (F) within the frequency range that SCS patients experience significant reduction in symptoms such as back pain. Advantageously, sub-perception stimulation at such low frequencies significantly reduces power consumption in the patient's neurostimulator.

The invention relates to a packaging body for a medical implant, in particular a pacemaker and / or a neurostimulator, having a housing and a wire electrode connected to the housing, having a contact electrode arranged in a distal end region of the wire electrode, comprising packaging material which comprises closure means running along a sealing contour of the packaging material, wherein at least part of the packaging material and the closure means delimit a sterile and / or sterilisable interior of the packaging body, in which the implant is accommodated in a sterilely packaged state, wherein the packaging body, in particular in the interior, comprises electrically conductive contact means which are arranged such that, in the sterilely packaged state, the contact electrode of the implant, which is spaced apart from the housing of the implant by the wire electrode and is simultaneously electrically, and preferably mechanically, connected to the implant via the wire electrode, comes into contact, or can be brought into contact, with the contact means.

A neurostimulator is implantable into a body of a subject to treat an overactive bladder condition. The neurostimulator includes a pulse generator, circuitry, a lead, and a connector secured to the lead. The circuitry is disposed within the pulse generator and connected to a battery. The circuitry is configured to generate a stimulation signal with a duty cycle of between 0.1% and 2.5% and a total average current drain from the battery of between 0.1 μA and 5μA, the total average current drain including a background current, plus a stimulation current weighted by the duty cycle. The lead has an electrode assembly configured to direct the generated stimulation signal to tissue of the subject. The connector is adapted to allow the pulse generator to be detachable from and attachable to the lead.

A neural stimulation system may include at least one electrode contact and a neural stimulator configured to deliver stimulation therapy to a patient using an electrical waveform including a first phase of a first polarity and a second phase of a second polarity opposite the first polarity using the at least one electrode contact. The neural stimulator may be configured to therapeutically stimulate nervous tissue using both the first and second phases of the electrical waveform to provide stimulation therapy. The second phase removes accumulated charge caused by the first phase from the at least one electrode contact, and the first phase removes accumulated charge caused by the second phase from the at least one electrode contact. Benefits include reducing energy consumption, using a recharge pulse to activate a population of neuron devices to reduce energy consumption.

A method of treatment with an implantable neurostimulator device in which a low frequency waveform is applied by a pulse generator configured therein through a plurality of electrodes to a network of target interactive brain regions subject to an abnormal communication connection, in particular a central execution network, a default mode network and / or a highlight network, in some embodiments, the network may be configured to restore normal correlation or anti-correlation communication connections within and between networks to deal with brain-related dysfunctions.

A system may include a neurostimulator and a processing system, where the neuromodulator includes a directional lead. The processing system may be configured to perform a process that includes determining at least one stimulation field model (SFM) from at least a first vector that extends from a first virtual electrode on the directional lead and a second vector that extends from a second virtual electrode on the directional lead and determining a first modulation configuration corresponding to the first vector from the first virtual electrode and determining a second modulation configuration corresponding to the second vector from the second virtual electrode. The process may further include combining the first modulation configuration and the second modulation configuration into a combined modulation configuration and delivering neuromodulation via a single timing channel using the combined modulation configuration.

The invention relates to an RFID protocol based communication method for an implantable nerve stimulator system. The implantable nerve stimulator system comprises an in-vitro program control instrument and an implantable nerve stimulator, and the in-vitro program control instrument and the implantable nerve stimulator are in wireless communication by adopting a predetermined RFID protocol. The in-vitro program controller is configured to send a signal containing energy and control information to the implantable nerve stimulator. The implantable nerve stimulator is configured to: generate a sequence of stimulation pulses for application to the electrodes using the received stimulation parameters; self-state self-checking is executed according to a preset self-checking period; and when a query instruction from the in-vitro program controller is received, a state self-checking result is fed back to the in-vitro program controller. The frame structure of the predetermined RFID protocol comprises a seeker and a command field, and the seeker adopts a configuration mode of forbidding a lead code extension control bit; the command field includes a 4-bit command code, 8-bit or more valid data bits, and 5-bit CRC check bits.

The invention relates to a detector and a method for detecting the frequency of a neural signal, and to a device and a method for reproducing paged contents, in particular digital books. Another subject of the invention is a device for reproducing paged contents, the device comprising: - a permanent visual neural stimulator at a given frequency, the given frequency being associated with a given reproduction device command, the permanent visual neural stimulator being positioned on the reproduction device according to the associated given command. The user's interaction with the pages of the content is thus a hands-free solution that makes it possible to improve the user's experience. Such a reproduction device, in particular an e-reader, then takes advantage of the advances in brain computer interface (BCI) technologies by integrating this technology.

The invention relates to a wireless directional energy transfer system of a medical in-vitro program controller. The wireless directional energy transfer system comprises: a control device configured to generate a control signal for stimulation parameters of an in-vivo implantable nerve stimulator; a transceiver configured to convert the received control signal into an initial radio frequency signal; the transmitting link is used for transmitting the received initial radio-frequency signal to each of the plurality of transmitting branches, and each of the plurality of transmitting branches is used for processing the initial radio-frequency signal into a transmitting radio-frequency signal; the in-vitro antenna is used for transmitting a transmitted radio-frequency signal to the in-vivo antenna or receiving a radio-frequency signal from the in-vivo antenna; and the receiving link sends the received radio frequency signal to one of the plurality of receiving branches, and each of the plurality of receiving branches processes the received radio frequency signal into a received radio frequency signal and sends the received radio frequency signal to the transceiver, so that the transceiver converts the received radio frequency signal into a control signal and sends the control signal to the control device.

Provided is a closed-loop neuromodulation system involving coordinated intervention of the brain, the spinal cord, and the lumbosacral region, which comprises a deep brain stimulation unit (401), a deep brain field potential sensing unit (402), a spinal cord stimulation unit (501), an evoked potential sensing unit (502), a control decision-making unit (10), a deep brain electrode (403), a spinal cord electrode (503), a lumbosacral electrode (602), a docking lead (601), a radio frequency transmission unit (20), and a wireless charging and power management unit (30). By constructing an application strategy for coordinated regulation of the brain, the spinal cord, and the lumbosacral region, only one neurostimulator needs to be implanted. It can be used alone for brain diseases or spinal cord-related diseases, and can also be used for coordinated stimulation for motor function reconstruction and recovery in paralyzed patients and patients with motor dysfunction, as well as for the treatment of urinary system complications. The whole system is modular in application, can be selectively used according to disease conditions, and has a wider application range.

A powering system for constant current neural stimulators provides adaptive supply voltage for neural stimulators to decrease power dissipation by taking advantage of varying voltage compliance of constant current stimulation. The powering system includes an adaptive voltage supply generator, a monitoring circuit, a charge pump, a step-down converter, and a rechargeable battery.

An extendable and retractable electrical lead for providing electrical stimulation including an elongated lead body extending from a proximal portion to a distal portion, one or more electrical contacts carried by the proximal portion of the lead body configured to be coupled to an implantable neurostimulator, one or more electrodes carried by the distal portion of the lead body configured to electrically communicate with the one or more electrical contacts to deliver neurostimulation therapy to a target treatment site based on a stimulation therapy provided by an implantable neurostimulator; and a protective sheath coaxially aligned with the lead body along a common axis and extending over part of a length of the lead body, where the protective sheath is configured to slide relative to the lead body and the common axis between an extended state and a retracted state.

Systems and methods for customizable titration of an implantable neurostimulator are provided. A method of titrating a neurostimulation signal delivered to a patient from an implantable pulse generator includes delivering a first neurostimulation signal with a first set of parameters, increasing a first value of the first neurostimulation signal at a first rate for a first period of time while delivering the first neurostimulation signal, ceasing delivery of the first neurostimulation signal when the first value reaches a first target value, delivering a second neurostimulation signal with a second set of parameters, and increasing the second neurostimulation signal at a second rate for a second period of time while delivering the second neurostimulation signal.

An intra-oral appliance to power and / or communicate with a neurostimulator is provided. The intra-oral appliance can include a teeth covering configured to fit over mandibular incisor, canine and / or premolar teeth of a human being and a remote controller in the form of a housing extending posteriorly from and operably connected to the teeth covering. The housing can include a power source, a coupling coil configured to transmit power to the neurostimulator and configured to receive power from an external charger, and electrical circuitry operably connected to the coupling coil and the power source.