14 results about "Pelvic pain" patented technology

This invention relates to methods for treating endometriosis and providing effective contraception. Specifically, it relates to drospirenone in methods for treating endometriosis, endometriosis-associated pelvic pain (EAPP), and / or dysmenorrhea, the method comprising administering drospirenone in a biphasic regimen. The invention also relates to the use of drospirenone administered in such a biphasic regimen as a contraceptive and for inducing amenorrhea, and to pharmaceutical compositions and devices comprising drospirenone administered in such a biphasic regimen.

The present invention relates to levonorgestrel for use in a method for providing contraception in a female subject, comprising continuous intravaginal administration of levonorgestrel of from about 60 µg / day to about 100 µg / day. The invention further relates to levonorgestrel for use in a method for treating endometriosis, endometriosis associated pelvic pain (EAPP) and / or dysmenorrhea comprising continuously administering about 60 µg / day to about 160 µg / day of levonorgestrel. Delivery devices, preferably, intravaginal rings for putting the methods in practice are also envisaged.

A system for treating the chronic pelvic pain in a human subject, in particular a female human subject, comprises: a wearable thermal device (1; 1a; 1b), arranged for being worn by the aforesaid subject and releasing heat at a perineal or perineal-anal region of the aforesaid subject; a portable case (6), arranged for containing, sanitizing and thermally charging the wearable thermal device (1; 1a; 1b) when the latter is not in use; an underwear garment (20) of the female underpants type, arranged for housing the wearable thermal device (1; 1a; 1b), when the latter is in use, and comprising a pocket portion (21).

The present invention relates to levonorgestrel for use in a method of providing contraception to a female subject comprising a sustained intravaginal administration of levonorgestrel of about 60-100 [mu] g / day. The invention further relates to levonorgestrel for use in a method of treating endometriosis, endometriosis-associated pelvic pain (EAPP) and / or dysmenorrhea, comprising a sustained administration of levonorgestrel of about 60-160 [mu] g / day. Dosing devices, preferably vaginal rings, for carrying out these methods are also contemplated.

The present invention relates to drospirenone for use in a method for treating endometriosis, endometriosis associated pelvic pain (EAPP) and / or dysmenorrhea, comprising administering drospirenone in a biphasic regimen. The present invention furthermore relates to the use of drospirenone administered in such a biphasic regimen as a contraceptive and for inducing amenorrhea, as well as to a pharmaceutical composition and a kit comprising drospirenone administered in such a biphasic regimen.

An intravaginal electrical stimulation device for treating pelvic pain in a female patient includes, in one embodiment, a set of intravaginal components comprising a frame, at least one pair of paracervical electrodes, an intravaginal capsule, a socket in the proximal end of the intravaginal capsule, an electrode plug that plugs into the socket, and connecting wires that electrically couple the electrode plug to the paracervical electrodes. The intravaginal components are designed to inserted into the patient's vagina so that one or more electrodes are in direct contact with the vaginal epithelium in the lateral vaginal fornices. In some embodiments, a cutaneous electrode may be included to be attached to the skin of the female patient. A microprocessor and an electrical stimulation generator are operable to cause low-voltage electrical current to flow through the intravaginal electrodes, the cutaneous electrode, or both, to create one or more electrical fields that neuromodulate the intrapelvic nerves of the patient. An external controller, which communicates with the intravaginal components over a wireless data communications channel, sends instructions to and receives status updates from the microprocessor inside the intravaginal capsule. In some embodiments, the electrical stimulation generator is located inside an external electrical stimulator generator (EESG) worn outside the body, instead of being located in an intravaginally worn intravaginal capsule, and the EESG is electrically coupled to the intravaginal components via one or more connecting wires that pass through the orifice of the female patient's vagina.

The present disclosure provides methods of determining whether or not to administer a subject gabapentin, said method comprising assessing the genetic profile of a subject considered for a gabapentin-based therapy and determining, on the basis of the genetic profile, whether or not to administer the subject gabapentin.

The invention discloses a simulated massage device capable of relieving female chronic pelvic pain, which comprises an arc-shaped plate, a driving mechanism is mounted on the surface of the arc-shaped plate, a driving motor is welded to one end of the driving mechanism, the driving motor is located in the arc-shaped plate, a fixing seat is welded to one end of the driving motor, and the other end of the fixing seat is fixedly connected with a massage disc. And massage heads are adhered to the surface of the massage disc. According to the simulation massaging device capable of relieving the female chronic pelvic pain, the driving mechanism is installed on the surface of the arc-shaped plate, the driving motor is welded to one end of the driving mechanism and located in the arc-shaped plate, and the fixing base is welded to one end of the driving motor, so that massaging can be conducted through the massaging heads on the massaging disc; at the moment, manual work is replaced by automatic machinery, so that the labor burden is relieved, and the device is more convenient and faster to use, can continuously run for a long time and is very convenient to use.

The application belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating adenomyosis and application thereof. The traditional Chinese medicine composition is prepared from raw medicinal materials in the following mass fractions: 20-45 parts of Astragalus membranaceus, 10-15 parts of Ramulus Cinnamomi, 10-15 parts of Angelica sinensis, 10-15 parts of Fried Semen Persicae, 6-9 parts of Rhei Radix et Rhizoma with liquor, 10-12 parts of Poria cocos, 6-9 parts of Eupolyphaga, 6-9 parts of Yunnan giant Himalayan lily, and 3-6 parts of Panax notoginseng powder. The clinical research results prove that the traditional Chinese medicine composition can effectively treat adenomyosis of yang deficiency and blood stasis type, improve symptoms such as dysmenorrhea, chronic pelvic pain, menorrhagia, prolonged menstrual period and the like of patients, and improve hemoglobin level, while avoiding obvious adverse reactions, and therefore has good practical application value.

The present invention relates to the treatment of endometriosis using an anti-Netrin-1 antibody or an antigen-binding fragment thereof, and to such an antibody or fragment thereof for use in treating endometriosis. The treatment includes reduction of endometriotic lesions, particularly uterine and / or uterine horn endometriotic lesions. The treatment further includes relief of chronic pelvic pain or vaginal hyperalgesia. This may also include reduction of colorectal hyperalgesia developed in endometriosis, improvement of bladder dysfunction developed in endometriosis, reduction of increased skin sensitivity to heat and / or mechanical stimuli developed in endometriosis, and improvement of overall health status altered by endometriosis.

The present invention relates to drospirenone for use in a method for treating endometriosis, endometriosis associated pelvic pain (EAPP) and / or dysmenorrhea, comprising administering drospirenone in a biphasic regimen. The present invention furthermore relates to the use of drospirenone administered in such a biphasic regimen as a contraceptive and for inducing amenorrhea, as well as to a pharmaceutical composition and a kit comprising drospirenone administered in such a biphasic regimen.

An intravaginal device capable of supplying electrical stimulation is provided. In an example, the intravaginal device may be used to implement the TENS technique by stimulating nerves while positioned within a user's vagina. While positioned within the vagina, the provided medical device may stimulate the hypogastric nerve complex around the uterosacral ligaments. In some cases, the provided medical device may both apply electrical stimulation to treat pain and control bleeding during a menstrual cycle. For example, at least a portion of the provided medical device may include absorbent material, such as a tampon.

The present invention relates to drospirenone for use in a method for treating endometriosis, endometriosis associated pelvic pain (EAPP) and / or dysmenorrhea, comprising administering drospirenone in a biphasic regimen. The present invention furthermore relates to the use of drospirenone administered in such a biphasic regimen as a contraceptive and for inducing amenorrhea, as well as to a pharmaceutical composition and a kit comprising drospirenone administered in such a biphasic regimen.

The present invention relates to levonorgestrel used in a method of providing contraception in a female subject, comprising continuous intravaginal administration of approximately 60 μg / day to approximately 100 μg / day of levonorgestrel. Furthermore, the present invention relates to levonorgestrel used in a method of treating endometriosis, endometriosis-associated pelvic pain (EAPP), and / or dysmenorrhea, comprising continuous administration of approximately 60 μg / day to approximately 160 μg / day of levonorgestrel. A delivery device, preferably an intravaginal ring, for carrying out these methods is also envisioned.