111 results about "Adenomyosis" patented technology

The present invention relates to a method of preventing or treating benign estrogen sensitive gynecological disorders in a female mammal, wherein the method comprises the administration to said female mammal of a combination of progestogen and androgen in an amount that is therapeutically effective to prevent or reduce the symptoms of these disorders. The present method is particularly suitable for preventing or treating disorders selected from the group consisting of endrometriosis, adenomyosis, uterine fibroids, dysmenorrhoea, menorrhagia and metrorrhagia. Another aspect of the invention relates to a pharmaceutical kit comprising a plurality of oral dosage units which comprise a progestogen in an amount equivalent to 3-500 μg levonorgestrel and either 5 to 250 mg dehydroepiandrosterone or 1 to 50 mg testosterone undecanoate.

The present invention is directed to the neutralizing prolactin receptor antibody 002- H08, and antigen binding fragments, pharmaceutical compositions containing them and their use in the treatment or prevention of benign disorders and indications mediated by the prolactin receptor such as endometriosis, adenomyosis, non-hormonal female contraception, benign breast disease and mastalgia, lactation inhibition, benign prostate hyperplasia, fibroids, hyper- and normoprolactinemic hair loss, and cotreatment in combined hormone therapy to inhibit mammary epithelial cell proliferation. The antibodies of the invention block prolactin receptor-mediated signaling.

These electrostimulation processes and equipment are used in the control of pelvic pain of different etiologies, more particularly, pain resulting from dysmenorrhea and endometriosis, the process predicting the development of an electrostimulation protocol in which the variation of the intensity of the electric pulses is performed in a random manner, respecting the limits of efficacy of the stimulation, in order to reduce the physiological phenomenon of nerve fiber accommodation upon stimuli; and a portable electrostimulation device, consisting of a double bandage (1) formed by two sheets (2), each comprised of central portion (2a) and two side flaps (2b), the central portion (2a) of both sheets (2) housing between them a compartment (3), housing for the electronic module of the apparatus, and the two side flaps (2a) of the top sheet (2) housing the respective electrodes (4), duly covered by the respective gel layers protected by removable protective sheets (5); each one of the sheets (2) is additionally endowed with a respective fastening strip (6); a coin-shaped lithium-ion supply battery (8), model CR20XX, a single on-off button (9), and the following internal components are provided: Power source module (10), step-up regulator module (11), micro controller module (12), power supply seal module (13), boost source module (14), H-bridge module (15), and electrode output module (16).