The invention discloses a health-care product for preventing and treating premature ovarian failure and a preparation method thereof. The health-care product comprises medlar, glossy privet fruit, prepared rehmannia, epimedium, malaytea scurfpea fruit, Chinese dodder seeds, raspberry, peanut, Chinese date and soy. The preparation method comprises the following steps of: weighing raw materials according to a weight proportion; soaking with ethanol; performing reflux extraction; filtering, and keeping the filtrate for later use; performing reflux extraction on the residue twice with ethanol; re-filtering, and keeping the filtrate for later use; combining the filtrate, and concentrating the filtrate until ethanol odor does not exist so as to obtain ethanol extract; and decocting the residue twice, filtering to obtain water extract, and combining the ethanol extract and the water extract to obtain the health-care product. The health-care product has excellent effect of improving the ovary function, and has the effects of improving the ovary function, achieving the effect of estrogen, improving the symptoms of weight loss, desudation and the like caused by ovarian failure, regulating the response of the ovary to gonadotropin, promoting follicular development and the like for 40-year-old women particularly.