288 results about "Myoma" patented technology

The present invention relates to apparatus and methods for thermally ablating uterine fibroids. More particularly, the present invention relates to a conduit having a plurality of channels for delivering a plurality of thermal ablation probes to an organic target such as a uterine fibroid, the probes being delivered in such configuration and orientation as to enable efficient and thorough ablation of the fibroid. In a preferred embodiment, the conduit is formed as a sleeve having a large central lumen sized to accommodate a hysteroscope, channels sized to accommodate cryoprobes are used as thermal ablation probes, and comprises thermal insulation materials serving to protect the cervix from damage by cold. The present invention further relates to bent cryoprobes usable in conjunction with such a conduit and designed to exit therefrom in a desired configuration useful for ablating a large fibroid.

A high-power ultrasound heating applicator for minimally-invasive thermal treatment of uterine fibroids or myomas. High-intensity interstitial ultrasound, applied with minimally-invasive laparoscopic or hysteroscopic procedures, is used to effectively treat fibroids within the myometrium in lieu of major surgery. The applicators are configured with high-power capabilities and thermal penetration to treat large volumes of fibroid tissue (>70 cm³) in short treatment times (3-20 minutes), while maintaining three-dimensional control of energy delivery to thermally destroy the target volume.

The present invention relates to a combination of resveratrol with progestogen, and medicaments and pharmaceutical compositions containing the same, which are useful in the treatment and/or prevention of myoma and/or endometriosis, providing their size reduction and the control of related symptoms. Said association may additionally comprise an estrogen component. A treatment method and a kit are also objects of this invention.

The invention is directed to a uterine artery clamp and the relatively non-invasive treatment procedure utilizing this clamp. The uterine clamp includes a clamping member having a jaw with tissue-contacting surfaces for applying pressure to target tissue and a stabilizing member which is configured to be inserted into the patient's uterine cervical canal. The clamp may be provided with elongated handles to manually adjust the spacing between the jaw and stabilizer and thereby apply pressure to a uterine artery beneath a bundle of tissue held between the jaw and stabilizer. Uterine clamps embodying features of the invention by be used in procedures for treating uterine disorders such as fibroids, DUB, PPH and the like.

The invention discloses a novel traditional Chinese medicinal composition for treating ovarian cyst and a preparation method thereof. The traditional Chinese medicinal composition mainly comprises the following raw material medicines: pangolin scales, tribulus terrestris, spina gleditsiae, rhizoma sparganii, zedoary, leech, ground beeltle, aspongopus, dragon's blood, Chinese trumpet creeper, cowherb seed, suberect spatholobus stem, twotooth achyranthes root, motherwort herb, peach kernel, red flower, szechuan lovage rhizome, immature bitter orange, szechwan chinaberry fruit, pseudoginseng root, cyperus rotundus, Chinese eaglewood and the like. The traditional Chinese medicinal composition can be prepared into any common oral preparation according to the conventional traditional Chinese medicinal preparation method, can obviously improve abnormal menstruation caused by myoma of uterus, colporrhagia, increased leucorrhea, abdomen bilge pendant, abdominal pain, frequent micturition and urination disorder due to myoma pressure on the bladder, constipation and impeded defecating due to myoma pressure on the rectum and other symptoms, and has the advantages of obvious inhibition of cyst hyperplasia, prevention of cancerization, exact clinical curative effect, obvious curative effect, quick response, low cost, fundamentally no toxic or side effect, and the like.

A method for treating a uterine fibroid comprises forming an incision in a vaginal fornix to expose a first blood vessel supplying the fibroid, forming an opening in the first blood vessel and inserting an introducer into the first blood vessel via the opening in combination with the steps of advancing a catheter to a desired position within the first blood vessel via the introducer and introducing an occlusive agent into the first blood vessel through the catheter to block blood flow through the first blood vessel. A device for treating uterine fibroids comprises an elongated sheath sized for insertion into uterine arteries via an incision in the vaginal fornix, the sheath including a sheath lumen extending from a first sheath opening formed in a proximal end of the sheath to a second sheath opening formed in a distal end of the sheath and a body a distal end of which is connected to the proximal end of the sheath, the body including a body lumen extending therethrough from a first body opening at a proximal end of the body and a second body opening at the distal end thereof, the second body lumen communicating with the sheath lumen in combination with a hemostatic valve controlling the flow of blood through the body lumen.

The invention relates to a manufacture method for a traditional Chinese medicine moxa stick with the efficacy of warming the uterus for dispelling cold. The traditional Chinese medicine moxa stick is prepared from the following raw materials in percentage by weight: 70-85% of three-year aged moxa floss and 30-15% of traditional Chinese medicine powder, wherein the traditional Chinese medicine powder comprises the following components in weight proportion: 3-5 g of angelica sinensis, 3-7 g of white paeony root, 3-7 g of salvia miltiorrhiza, 3-5 g of ligusticum wallichii, 3-5 g of carthamus tinctorius, 3-7 g of cyperus rotundus, 3-7 g of peach seed, 3-7 g of achyranthes bidentata, 3-7 g of leonurus artemisia, 3-7 g of rhizoma corydalis and 3-7 g of cassia twig. The manufacture method comprises the following steps: respectively weighing traditional Chinese medicines according to the weight proportion, smashing the traditional Chinese medicines, screening the smashed traditional Chinese medicines through a 100-mesh sieve, mixing the powders into the traditional Chinese medicine powder, and mixing the traditional Chinese medicine powder into the moxa floss according to the weight proportion so as to obtain the traditional Chinese medicine moxa stick. Targeted acupoints are selected to be subjected to moxibustion, so that the traditional Chinese medicine moxa stick is highly targeted, and especially can be used for conditioning, prevention and treatment for females with cold hands and feet, intolerance of cold, sensation of chill, soreness of waist, weakness, irregular menstruation, dysmenorrheal, hysteromyoma, ovarian cyst, cold in uterus, infertility and other symptoms.

The invention discloses a traditional Chinese medicine composition for treating the symptoms of qi stasis, blood stasis, myoma and cyst and a preparation method. The traditional Chinese medicine composition mainly comprises the following raw materials of medicines: tangerine peel, immature bitter orange, rosa banksiae, rhizoma cyperi, TurmericRoot-tuber, medicated leaven, Chinese eaglewood, radix linderae, toosendan fruit, fructus citri sarcodactylis, malt, hawthorn, rhizoma ligustici wallichii, radix salviae miltiorrhizae, peach kernel, safflower, rhizoma sparganii, rhizoma zedoariae, scaly anteater, carapax amydae, tortoise plastron, semen raphani, green tangerine peel, radix aristolochiae, longstamen onion bulb, citron, scorched areca, dried ginger, corydalis tuber, curcuma, trogopterus dung, motherwort, spatholobus stem, logwood, draconis sanguis, red peony root, white peony root, angelica and the like. The traditional Chinese medicine composition can be prepared into any common oral preparation according to a conventional traditional Chinese medicine preparation method. The invention can obviously improve the physical signs of the whole bodies of patients with the symptoms of qi stasis, blood stasis, myoma and cyst, regulates the viscera functions of the patients, regulates the circulation of the qi and the blood of an organism, removes the qi stasis and the blood stasis, eliminates lumps, calms down the stasis and has definite clinical curative effect, obvious curative effect and quick acting. As basically adopting medicine-food homologous medicines specified by the dispensatory of China for combination, the traditional Chinese medicine composition has the advantages of low cost, no toxic or side effect basically and the like.

A gonadotropin-releasing hormone antagonistic composition, which comprises an optionally substituted condensed-bicyclic compound consisting of a homo or hetero 5 to 7 membered ring and a homo or hetero 5 to 7 membered ring is effective as a propylactic or therapeutic agent for the prevention or treatment of several hormone dependent diseases, for example, a sex hormone dependent cancer (e.g. prostatic cancer, cancer of uterine cervix, breast cancer, pituitary adenoma), benign prostatic hypertrophy, myoma of the uterus, endometriosis, precocious puberty, amenorrhea, premenstrual syndrome, polycystic ovary syndrome and acne vulgaris; is effective as a fertility controlling agent in both sexes (e.g. a pregnancy controlling agent and a menstrual cycle controlling agent); can be used as a contraceptive of male or female, as an ovulation-inducing agent of female; can be used as an infertility treating agent by using a rebound effect owing to a stoppage of administration thereof; is useful as modulating estrous cycles in animals in the field of animal husbandry, as an agent fro improving the quality of edible meat or promoting the growth of animals; is useful as an agent of spawning promotion in fish.

The present invention relates to a novel class of AKR1C3 inhibitors, to compositions containing them, to methods for their preparation, and to methods of use thereof. The AKR1C3 inhibitors may be useful in the treatment of, for example, prostate cancer, benign prostate hyperplasia (BPH), lung cancer, acne, seborrhea, hirsuitism, baldness, alopecia, precocious puberty, adrenal hypertrophy, polycystic ovary syndrome, breast cancer, uterine cancer, uterine fibroids, endometriosis, myeloma and leiomyoma.

This invention is directed to pyrrole, pyrazole, imidazole, triazole, and morpholine based selective androgen receptor degrader (SARD) compounds including heterocyclic anilide rings and their synthetic precursors, R-isomers, and non-hydroxylated and/or non-chiral propanamides, and pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, triple negative breast cancer, other cancers expressing the androgen receptor, androgenic alopecia or other hyperandrogenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), abdominal aortic aneurysm (AAA), and uterine fibroids, and to methods for reducing the levels of androgen receptor-full length (AR-FL) including pathogenic or resistance mutations, AR-splice variants (AR-SV), and pathogenic polyglutamine (polyQ) polymorphisms of AR in a subject.

The present invention provides a vaginally administrable tablet useful for treating leiomyomata, leiomyoma, myoma, uterine fibroids, endometriosis, adenomyosis and other related disorders. The tablet comprises mifepristone, at least one non-effervescent excipient or diluent, and at least one effervescent excipient.

The invention discloses a novel traditional Chinese medicinal composition for treating myoma of uterus and a preparation method thereof. The traditional Chinese medicinal composition mainly comprises the following raw material medicines: baked pangolin scales, peach seed, red flower, baked frankincense, baked myrrh, salvia miltiorrhiza, scirpus maritimus, zedoary, ground beeltle, sappan wood, dragon's blood, Liujinong, leech (baked abrasive powder), motherwort herb, cowherb seed, szechuan lovage rhizome, rhizoma corydalis, curcuma tuber, green tangerine peel, tangerine peel, Chinese eaglewood, aspongopus, chicken's gizzard-membrane and the like. The traditional Chinese medicinal composition can be prepared into any common oral preparation according to the conventional traditional Chinese medicinal preparation method. The novel traditional Chinese medicinal composition can obviously inhibit the growth of myoma of uterus, controls the development speed of myoma, prevents the degeneration of myoma, abdominal swelling and pain, colporrhagia, palpable mass on the abdomen and pressure symptom, and the like, and has exact clinical curative effect, obvious curative effect and quick response. The traditional Chinese medicinal composition also has the advantages of low cost, basically no toxic or side effect and the like.

The invention discloses a medicament for treating myoma of uterus, which is characterized by being prepared from the following raw materials in part by weight: 1 to 20 parts of rose, 1 to 20 parts of seville orange flower, 1 to 20 parts of Chinese angelica, 1 to 20 parts of red paeony root, 1 to 20 parts of szechuan lovage rhizome, 1 to 20 parts of red tangerine peel, 1 to 20 parts of rhizome pinelliae preparata, 1 to 20 parts of honey-fried liquorice root, 1 to 20 parts of pared nutgrass galingale rhizome, 1 to 20 parts of scrophularia root, 1 to 20 parts of thunberg fritillary bulb, 1 to 20 parts of dipsacus asper, 1 to 20 parts of fructus aurantii immaturus, 1 to 20 parts of sudden smile powder, 1 to 20 parts of raw hawthorn fruit, 1 to 20 parts of oyster shell, 1 to 20 parts of spreading hedyotis herb, 1 to 20 parts of zedoary and 1 to 20 parts of over 95 percent edible ethanol. The medicament can be used for oral administration and absorbed by the spleen and stomach and can be used for external use and absorbed by skin, and can be absorbed complexly in two modes of oral administration and external use. The medicament has the advantages of addressing both the symptoms and root causes along with reasonable formula, simple compatibility and definite curative effect, and is particularly suitable for infecund patients caused by blood stasis and qi depression and phlegm-damp stagnation. The invention also provides a preparation method of the medicament.

The invention provides a traditional Chinese medicine composition for treating lobular hyperplasia of mammary glands and breast tumor. The traditional Chinese medicine composition consists of the following components in certain parts by weight: Chinese thorowax root, nutgrass galingale rhizome, Chinese angelica, Szechuan lovage rhizome, danshen root, pangolin scales, zedoary rhizome, milkvetch root, Indian buead, motherwort herb, common burreed rhizome, deerhorn, dried tangerine peel, green tangerine peel, peach seeds, bulb of thunberg fritillary, fruit-spike of common selfheal, frankincense, tangerine seeds, licorice root, cowherb seed, safflower, turmeric root-tuber, towel gourd vegetable sponge, cochinchnese asparagus root, Mongolian dandelion herb, pseudobulb of appendiculate cremastra, corydalis tuber, beautiful sweetgum fruit, honeysuckle flower, coptis chinensis, figwort root, pinellia tuber and glossy privet fruit. The traditional Chinese medicine composition provided by the invention can be used for treating diseases such as lobular hyperplasia of mammary glands, breast benign tumor and uterine myoma, is significant in effect, cannot cause toxic or side effects, ensures that the effective treatment rate can reach 96%, and is not easy to cause recurrence.

The present invention relates to a bipolar electrode and its connection structure. It is a bipolar operation electrode matched with electroresectoscope for use. Said invention mainly is used for resecting body of gland due to hyperplasia of prostate, tumor of bladder and submucosal myoma of uterus, etc. Said bipolar electrode self-body not noly has a working electrode, but also has a loop electrode, and said current is not passed through the human body, so that it can prevent the burn phenomenon which can be produced when the monopolar electrode current is passed through negative electrode plate of human body and its contact is poor. Said bipolar electrode uses physiological saline as buffer solution, so that it can prevent TURP syndrome which is easily produced by adopting monopolar electrode. The operation method of said bipolar electrode is identical to that of monopolar electrode, and its connection is convenient, and safe and reliable.

The subject matter of the instant invention is pertinent to the field of treatment of hormone-dependent conditions. New compounds and methods for treating these conditions are disclosed. Embodiments of the instant invention disclose methods for treating endometriosis, dysmenorrhea, breast cancer, uterine fibroids and endometrial hyperproliferation.