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143 results about "Intraoperative navigation" patented technology
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Lung cancer intraoperative navigation positioning method based on three-dimensional reconstruction and deep neural network
The invention relates to the technical field of medical image processing and surgical navigation, in particular to a lung cancer intraoperative navigation and positioning method based on three-dimensional reconstruction and a deep neural network, which comprises the following steps of: based on multi-source optical and acoustic fusion, performing fractal wavelet multilayer decomposition on preliminarily purified data acquired in an operation, and performing multi-source optical and acoustic fusion; multi-modal characteristics of optical and acoustic channels and fractal measurement are obtained; using quantum heuristic multi-agent search to find a potential focus or a key area with serious deformation, and performing interpolation completion on a defect or noise part in a nerve radiation field; performing elastic deformation registration on the interpolation result and the lung three-dimensional model, and calculating a nonlinear deformation field and intra-operative tumor prediction coordinate data; and superposing the deformed lung model to an augmented reality environment through external tracking information to display the focus position. And when lung collapse or the traction amplitude exceeds the limit is monitored, searching and registration are repeated for real-time updating, and accurate navigation positioning under dynamic deformation of the lung is realized.
Owner:HUADONG HOSPITAL
Real-time intraoperative navigation system and method based on optical and inertial navigation
InactiveCN120036930AInternal combustion piston enginesSurgical navigation systemsAnatomical structuresAlgorithm
The invention relates to the technical field of medical surgical navigation, in particular to a real-time intraoperative navigation system and method based on optical and inertial navigation. The system comprises an optical data acquisition module which is used for acquiring images, identifying surgical instruments and anatomical structures of patients, and extracting corresponding feature points by adopting a mode of combining a feature point extraction algorithm based on deep learning with a traditional algorithm; calculating pose information by using a mode of fusing a pose resolving algorithm based on deep learning and a traditional algorithm; the inertial data acquisition module is used for integrating the data of each component of the IMU by using the IMU integrated component, establishing a state model and the observation module, and acquiring the attitude information of the surgical instrument; and the data fusion processing module is used for carrying out time synchronization and calibration of optical camera and IMU acquisition, and adopting different data fusion strategies according to the reliability and availability of optical data and inertial data. According to the technical scheme, the reliability of the intraoperative navigation system can be improved.
Owner:CHONGQING EMERGENCY MEDICAL CENT (CHONGQING FOURTH PEOPLES HOSPITAL CHONGQING INST OF EMERGENCY MEDICINE)
Control method of intestinal tumor resection robot combining preoperative image and intraoperative navigation
PendingCN120788742AMechanical/radiation/invasive therapiesSurgical navigation systemsAnatomical landmarkIntestino-intestinal
The invention provides a control method of an intestinal tumor resection robot combining preoperative images and intraoperative navigation, and relates to the technical field of medical instrument control. The method comprises the following steps: acquiring preoperative multi-modal image data of the intestinal tract of a patient, and performing three-dimensional reconstruction on the image data to generate an initial three-dimensional model; dividing a navigation area in the enteric cavity according to the initial three-dimensional model; based on the core area, collecting a dynamic image of the intestinal tract inner cavity in real time through intraoperative navigation equipment, extracting anatomical mark points in the dynamic image, registering the dynamic image with the initial three-dimensional model, updating tissue deformation parameters in the three-dimensional model, and obtaining an updated three-dimensional model; on the basis of the updated three-dimensional model, obstacles in the intestinal tract are recognized, and the minimum space distance between the obstacles and the robot tail end instrument is calculated; and according to the spatial distribution and the minimum spatial distance of the obstacles, an initial motion path of the robot tail end instrument is planned. According to the invention, the efficiency and accuracy of the intestinal tumor resection operation can be improved.
Owner:THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL
Catheter tip positioning method and system in central venous catheterization and medium
The invention provides a catheter tip positioning method and system in central venous catheterization and a medium, and relates to the field of medical image data processing. The system comprises a CT center line extraction module, a puncture position prediction module, a catheterization target calculation module, an ultrasonic center line extraction module, an image fusion module, a catheter position projection module and a catheterization completion judgment module. According to the intelligent navigation positioning technology in the central venous catheterization based on ultrasonic, CT and electromagnetic navigation multi-mode fusion, ultrasonic, CT, electromagnetic positioning and deep learning are creatively fused, accurate positioning and real-time monitoring of the tip of the catheter in the central venous catheterization are achieved, and the learning threshold is lowered.
Owner:RENMIN HOSPITAL OF WUHAN UNIVERSITY (HUBEI GENERAL HOSPITAL) +1
Anti-DDR2 nano-antibody and use thereof
PendingEP4567045A1In-vivo radioactive preparationsAntibody ingredientsDiseaseAntiendomysial antibodies
The present invention relates to anti-DDR2 antibodies. More specifically, the present invention relates to nano-antibodies binding to DDR2 and various derivatives of the nano-antibodies. The present invention also relates to pharmaceutical compositions comprising these antibodies and derivatives and pharmaceutical uses thereof. The anti-DDR2 nano-antibodies of the present invention have strong binding activity and can be used for diagnosis, prevention and / or treatment of diseases mediated by abnormal DDR2 expression (such as cancer and inflammatory diseases), as well as imaging of cells expressing DDR2, such as biopsy navigation and intraoperative navigation.
Owner:FIBRO-BIOMED TECH (GUANGZHOU) CO LTD
Neurosurgical operation data processing method for precision medical treatment
The invention relates to the field of data processing, and discloses a neurosurgery operation data processing method for precision medical treatment, which is used for solving the problem that mark points cannot be captured due to the fact that a navigation camera is shielded when intraoperative data is collected. The method comprises the following steps: acquiring preoperative image data, intra-operative navigation image data and spatial information of an intra-operative reference mark point, constructing a preoperative three-dimensional navigation model through the preoperative image data, obtaining a navigation coordinate system, obtaining an intra-operative image frame sequence through the intra-operative navigation image data, carrying out spatial registration, extracting intra-operative navigation information, and obtaining an intra-operative image frame sequence. The method comprises the following steps: acquiring intraoperative navigation information, judging whether occlusion occurs in an operation or not according to the intraoperative navigation information, if yes, generating missing image frame data during occlusion through a dynamic trajectory prediction model, and effectively judging the missing image frame data according to a newest instrument space pose, thereby effectively improving data integrity and coherence, improving operation data accuracy and improving operation accuracy. The operation risk is reduced.
Owner:JILIN UNIV FIRST HOSPITAL
Spatial registration and image fusion method for deep learning based on SS-OCT and TOF data
The invention discloses a spatial registration and image fusion method for deep learning based on SS-OCT and TOF data, relates to the technical field of multi-modal medical image processing, and aims to improve alignment and fusion effects based on SS-OCT and TOF blood vessel data. According to the method, firstly, blood vessel features are enhanced through preprocessing, precise registration and fusion of cross-modal data are achieved by combining high-resolution two-dimensional tomography of SS-OCT and three-dimensional blood vessel form data of TOF and utilizing an improved SIFT algorithm and a cross attention Transformer model, and finally a high-precision three-dimensional blood vessel model is generated and can be used for treating cerebrovascular diseases (such as cerebrovascular diseases). Image support with details and a global structure is provided for preoperative planning and intraoperative navigation of a patient (such as aneurysm and stenosis), and the accuracy of diagnosis and treatment is remarkably improved.
Owner:CHANGCHUN UNIV OF SCI & TECH
Intraoperative pulmonary nodule positioning method and system based on fusion of CT image and endoscope video
The invention discloses an intraoperative pulmonary nodule positioning method and system based on fusion of a CT image and an endoscope video. The method comprises the following steps: firstly, constructing a three-dimensional lung model containing a pulmonary nodule position based on preoperative high-resolution CT data; generating a real-time lung surface model by using an endoscope video stream through a three-dimensional reconstruction technology during the operation; a feature point extraction and matching algorithm is adopted, and a non-rigid registration technology is combined to realize accurate registration of the preoperative model and the intraoperative dynamic model; projection display of pulmonary nodules in a real-time endoscope visual field is established through space coordinate mapping, and a dynamic compensation algorithm is developed to solve the problem of tissue deformation caused by respiratory movement and instrument operation. Meanwhile, the virtual nodule position is overlaid to an endoscope video picture through the augmented reality technology, and visual intraoperative navigation is provided for surgeons. The method effectively solves the technical bottleneck that a traditional method depends on a metal marker and cannot adapt to intraoperative tissue deformation and the like, and has clinical practical value.
Owner:THE SECOND AFFILIATED HOSPITAL OF NANJING UNIV OF TRADITIONAL CHINESE MEDICINE (JIANGSU SECOND HOSPITAL OF TRADITIONAL CHINESE MEDICINE JIANGSU TRAINING CENT FOR TRADITIONAL CHINESE MEDICINE MANAGEMENT CADRES)
Lung three-dimensional reconstruction method and system for intraoperative positioning
The invention discloses a lung three-dimensional reconstruction method and system for intraoperative positioning, and the method comprises the steps: processing a lung CT image in a DICOM format through an improved lung parenchyma segmentation algorithm, precisely extracting a lung structure through a global threshold method, connected region analysis and mathematical morphology processing, and then processing a mask generated through segmentation through a real-time smooth interpolation method, and through a dynamic parameter adaptation technology, accurate matching of a segmentation result and a gray value range of modeling data is ensured. According to the method, the problems of artifacts, redundant surfaces and gray level jump of the lung parenchyma area caused by separation of segmentation and reconstruction in a traditional method are avoided, full-process automation from data reading and lung parenchyma segmentation to three-dimensional modeling and visualization is achieved, meanwhile, a user-friendly interaction interface is designed, and a convenient tool is provided for intraoperative navigation.
Owner:NANJING UNIV OF POSTS & TELECOMM
Multi-modal medical image intelligent analysis system and method based on large language model
The invention provides a multi-modal medical image intelligent analysis system and method based on a large language model, and the system comprises a key frame extraction module which carries out the key frame extraction through a multi-frame quality evaluation algorithm; the coronary artery blood vessel extraction module is used for realizing accurate extraction of a coronary artery tree structure through multi-scale blood vessel enhancement; the pathological recognition module adopts an improved DeepLabV3 + algorithm to construct a cardiac blood vessel blockage region segmentation model; the multi-modal diagnosis module adopts LLaVA-Med multi-modal diagnosis, integrates vision and language understanding ability, and combines DeepSeek to generate a standardized diagnosis report; the model optimization module is used for implementing model parameter iterative updating based on a near-end strategy optimization algorithm; and the visual interaction module is used for visually displaying the lesion position and the spatial relationship thereof, so that a doctor can conveniently carry out preoperative path planning and intraoperative navigation judgment. On the basis of a large language model and a multi-mode technology, full-process support from image uploading to diagnosis decision making is provided.
Owner:SHANGHAI OCEAN UNIV
Training method of CT and DSA real-time automatic fusion registration system for structural heart disease intervention and storage medium
The invention provides a training method of a CT and DSA real-time automatic fusion registration system for structural heart disease intervention and a storage medium. The training method comprises the following steps: establishing a registration system data set; establishing an initial registration system; based on the registration system data set, training an initial registration system to obtain a trained CT and DSA intraoperative registration system; and inputting the preoperative CT image data and the intraoperative real-time DSA image data of the person to be identified into the trained CT and DSA intraoperative registration system to obtain an intraoperative real-time fusion navigation image and intraoperative risk graphical prompt information. According to the method, cross-modal and cross-time-point dynamic registration can be realized, higher-precision intraoperative navigation support is provided for structural heart disease intervention, the operation safety is improved, and radiation exposure is reduced.
Owner:RENJI HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
Markerless navigation system
ActiveUS12465429B2Image enhancementMechanical/radiation/invasive therapiesAnatomical structuresNavigation system
A surgical system and method for markerless intraoperative navigation is provided. The system can includes a structured light system that can be utilized to intraoperatively sense three-dimensional surface geometry. The computer system is configured to segment a depth image to obtain surface geometry data of an anatomical structure embodied within the depth image, register the surface geometry data of the anatomical structure to a model, and update the surgical plan according to the registered surface geometry data. The surgical system is an endoscopic surgical system.
Owner:SMITH & NEPHEW INC +2
Application of near-infrared fluorescent probe of targeted folate receptor in preparation of near-infrared first region and near-infrared second region diagnostic drugs
The invention provides application of a near-infrared fluorescent probe of a targeted folate receptor in preparation of a near-infrared first region and near-infrared second region diagnostic drug, and relates to the technical field of organic fluorescent molecules. The folate receptor-targeted near-infrared fluorescent probe has a structural formula as shown in a formula I which is described in the specification. The near-infrared fluorescent probe provided by the invention has good tumor targeting capability and water solubility, also has near-infrared two-region developing capability, and has huge development potential and application prospect in fluorescence-guided intraoperative navigation. # imgabs0 #
Owner:NANJING NUOYUAN MEDICAL DEVICES CO LTD
Maxillofacial surgery planning navigation method and system
The invention provides a maxillofacial operation planning navigation method and system, relates to the technical field of operation planning navigation, and solves the technical problems that the existing maxillofacial operation planning navigation method cannot adapt to the change of an intraoperative anatomical structure due to a preoperative planning static state, and the intraoperative navigation efficiency and precision are insufficient. The method specifically comprises the following steps: acquiring first image data of a to-be-operated region; preprocessing the first image data based on an image processing algorithm to determine second image data; performing three-dimensional reconstruction and segmentation on the second image data to obtain a three-dimensional data model; analyzing the three-dimensional data model through an AI intelligent auxiliary diagnosis model, and generating a diagnosis report; inputting the three-dimensional data model and the diagnosis report into a two-channel model, and outputting an operation path scheme and a bone fracture plate scheme; in the operation, non-rigid registration is adopted to compensate real-time deformation delay for first image data before the operation and in the operation, and an AR real-time navigation technology is combined to realize maxillofacial operation planning navigation. The method is used for maxillofacial surgery planning navigation.
Owner:HEFEI JIMAI INTELLIGENT EQUIP CO LTD
Human-derived hysteromyoma targeting peptide and application thereof
PendingCN121851110ALuminescence/biological staining preparationBiological material analysisImmunogenicityPhage Display Techniques
The invention discloses a human-derived hysteromyoma targeting peptide and application thereof, the sequence of the targeting peptide is selected from SEQ ID NO: 1 to SEQ ID NO: 5, and the SEQ ID NO: 1 (VN12) is the most preferable. The fusion protein is obtained by screening through a phage display technology, and has high hysteromyoma targeting specificity and low immunogenicity. The targeting peptide can be coupled with nuclide or fluorescent dye, and is used for accurate PET imaging, fluorescent diagnosis and intraoperative navigation of hysteromyoma. Experiments prove that the molecular marker is specifically enriched in tumor tissues (the tumor / muscle ratio is 60), the biological safety is good, the problems of insufficient diagnosis sensitivity and large treatment wound in the prior art are solved, and the molecular marker has a great application prospect in diagnosis and treatment of hysteromyoma.
Owner:TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH
Calibration device for intraoperative navigation switching
Owner:FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA
Pre-hospital emergency treatment and in-hospital emergency treatment information integrated processing method and system
PendingCN120199423AMechanical/radiation/invasive therapiesHealth-index calculationUltra-widebandOrthopedic department
The embodiment of the invention provides a pre-hospital emergency treatment and in-hospital emergency treatment information integrated processing method and system. The method comprises the following steps: capturing three-dimensional space coordinates of a motion trail of an affected limb in real time, and collecting dynamic roundness deviation data; establishing a dynamic first-aid parameter matching mechanism at the edge AI node to perform multi-modal coupling analysis, and generating a first-aid decision vector set carrying fracture parting codes; establishing a pre-hospital-in-hospital information synchronization channel based on an ultra-wideband positioning network, transmitting the emergency decision vector set to a target hospital emergency center, and triggering a multi-modal resource scheduling mechanism of emergency department and orthopedic operating rooms; and automatically generating an analyzable operation preparation instruction set according to the operation guide plate parameter library, and driving the orthopedic operation navigation equipment to be initialized. According to the technical scheme provided by the embodiment of the invention, a full-link closed loop from pre-hospital first aid to intraoperative navigation is realized, the treatment time window is remarkably shortened, and the risks of secondary injury and prosthesis dislocation are reduced.
Owner:THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL
A method for simulating the stress distribution of a heart valve and perivalvular tissue by a guide wire
The present application relates to the technical field of medical devices, and discloses a method for simulating stress distribution of a guide wire on a heart valve and perivalvular tissue, comprising: obtaining image data of the heart valve and perivalvular tissue of a patient before surgery, and obtaining strain of each structure; constructing a material constitutive equation of the heart valve and perivalvular tissue to determine stress-strain relationship of each structure under different stress conditions; determining first stress distribution of the heart valve and perivalvular tissue according to the strain of each structure in the heart valve and perivalvular tissue and the stress-strain relationship of each structure under different stress conditions; obtaining second stress distribution of the guide wire when the guide wire is in different morphological positions in the heart valve; and determining third stress distribution of the guide wire on the heart valve and perivalvular tissue when the guide wire is in different morphological positions in the heart valve according to the first stress distribution and the second stress distribution, so as to accurately perform intraoperative navigation of the guide wire.
Owner:XI AN JIAOTONG UNIV
System and method for a two-step registration procedure enabling complete robotic surgical intervention
The present invention provides a system and method for a two-step registration procedure that enables complete surgical intervention by a robot. [Solution] A system for intraoperative navigation is provided, comprising a processing unit and a tracking device for real-time or near-real-time tracking of an object in a 3D coordinate system, wherein the processing unit is configured to receive an X-ray image depicting an anatomical structure including at least one bone, and to determine an incomplete registration of the position of the anatomical structure in the 3D coordinate system. The incomplete registration is determined based on a 3D dataset of the received anatomical structure and a plurality of virtual X-ray images generated from different directions based on the 3D dataset of the anatomical structure. The incomplete registration can be understood as an approximation of the position of the anatomical structure. Based on the incomplete registration, instructions for the navigation of the device are provided.
Owner:METAMORPHOSIS GMBH
Special skull sheet structure for intraoperative navigation frame
The utility model discloses a special skull drape structure for an intraoperative navigation frame, which comprises a skull drape main body and a navigation port covering sheet, a navigation frame abdicating port is arranged on the skull drape main body at the head position of a patient, a rod part through hole is arranged at the center of the navigation port covering sheet, and the navigation port covering sheet is sewed and mounted at the navigation frame abdicating port through a connecting part. The navigation opening covering piece can completely cover the navigation frame receding opening through overturning, the navigation opening covering piece is of a circular structure and is provided with an opening, and the opening extends into the rod portion penetrating hole from the edge of the navigation opening covering piece in the radius direction of the navigation opening covering piece. The device is suitable for the skull drape, the navigation opening covering sheet is designed to be of the circular sheet-shaped structure with the opening, therefore, after the navigation frame is installed, the navigation frame can be directly wound around the navigation frame and turned over to cover the navigation frame receding opening, and the navigation opening covering sheet can completely and flatly cover the navigation frame receding opening; and the condition that the positions of the navigation frames are uneven is avoided.
Owner:THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL
Surgical navigation system and method based on electromagnetic positioning and augmented reality
The invention provides a surgical navigation system and method based on electromagnetic positioning and augmented reality, and the system comprises an image data three-dimensional reconstruction module which is used for importing preoperative medical image data into the system, and generating a visual model through a three-dimensional reconstruction algorithm; the pre-operation registration module is used for realizing space mapping of an image coordinate system and an operation coordinate system through a registration method based on mark points; the electromagnetic positioning and coordinate mapping module is used for tracking the pose of the surgical instrument in real time and mapping the coordinates of the instrument to the surgical coordinate system; the augmented reality and high-precision navigation module is used for fusing and displaying the registered virtual navigation image and a real operation scene; the electromagnetic positioning and coordinate mapping module and the augmented reality and high-precision navigation module form a surgical navigation platform integrating electromagnetic tracking and augmented reality display; by fusing the high-precision anti-shielding capability of electromagnetic positioning and the visual visualization effect of augmented reality, stable, accurate and visual intraoperative navigation can be realized.
Owner:FUZHOU UNIV
Preoperative image registration processing method, device, system and storage medium
The application relates to the technical field of image processing, and provides a preoperative image registration processing method, device, system and storage medium, which can provide navigation information for intraoperative navigation in the scene of preoperative image guided puncture and lack of intraoperative real-time scanning image. According to each group in the respiratory phase sequence from the respiratory phase change of the preoperative image to the intraoperative respiratory phase, the image statistical shape model and the deformation field statistical shape model are determined according to the two respiratory phases of the group; the image weight of the group is obtained according to the image statistical shape model of the group and the image corresponding to the preceding respiratory phase; the weight proportion coefficient target value of the group is obtained based on the joint of the image statistical shape model and the deformation field statistical shape model of the group, and then the deformation field weight of the group is obtained in combination with the image weight; the deformation field of the group is obtained according to the deformation field weight and the deformation field statistical shape model of the group; and the preoperative image is registered and deformed according to the deformation fields of the groups.
Owner:WUHAN UNITED IMAGING HEALTHCARE SURGICAL TECH CO LTD
Nanoparticle with fluorescence enhancement performance and preparation method and application thereof
This invention discloses a fluorescence-enhancing nanoparticle, its preparation method, and its applications, relating to the fields of organic fluorescent molecules and bioimaging technology. The nanoparticle comprises: NIR-II fluorescent molecules and an amphiphilic polymer encapsulating the NIR-II fluorescent molecules; the amphiphilic polymer has a hydrophilic segment and a rigid hydrophobic segment. The nanoparticle of this invention, based on "carrier microenvironment engineering," utilizes the rigid confinement and interfacial isolation provided by the amphiphilic polymer with the rigid hydrophobic segment for dual brightening, serving as a universal brightening platform applicable to various NIR-II fluorescent molecules. This nanoparticle can significantly improve aqueous phase quantum yield, enhance contrast and resolution in in vivo vascular imaging, improve deep tissue penetration, increase imaging sensitivity, and facilitate detection under low signal conditions. It also exhibits good stability and biocompatibility, supporting lesion imaging and intraoperative navigation applications.
Owner:SHENZHEN UNIV
Preoperative imaging combined with intraoperative navigation before and after removal of an implant from a surgical site to create a composite surgical three dimensional structural dataset
Owner:JPI CONSULTING INC
Near-infrared fluorescent probe for active targeting of fibroblast growth factor receptor and preparation method and application thereof
The present invention provides a near-infrared fluorescent probe for active targeting of fibroblast growth factor receptors and a preparation method and application thereof, and relates to the technical field of specific molecular targeted diagnostic reagents. The near-infrared fluorescent probe for active targeting of fibroblast growth factor receptors of the present invention can be quickly cleared in normal tissues and stays in the tumor site for a long time, thereby achieving the effect of in vivo diagnosis, having certain clinical application prospects, and being applied to clinical intraoperative navigation.
Owner:NANJING NUOYUAN MEDICAL DEVICES CO LTD
Preoperative imaging combined with intraoperative navigation before and after alteration of a surgical site to create a composite surgical three dimensional structural dataset
Owner:JPI CONSULTING INC
High tibial osteotomy navigation method and system and storage medium
The application relates to the technical field of orthopedic surgery navigation, and discloses a high-position tibial osteotomy navigation method, a system and a storage medium, and a communication method which comprises the following steps: generating a 3D bone model of a lower limb of a patient based on medical images and performing preoperative osteotomy planning; performing visual positioning system detection and spatial calibration of a surgical instrument; installing an optical marker array, collecting actual bone point cloud data, and realizing alignment of the model and the bone through a registration algorithm; in-surgery real-time calculation and display of deviation of an operation track and planning parameters; post-surgery reconstruction of a lower limb force line, and comparison and evaluation with preoperative planning and in-surgery navigation records. The system comprises a hardware execution unit and preoperative planning, calibration verification, in-surgery registration, real-time navigation and post-surgery evaluation modules. The application realizes full-process integration of preoperative accurate planning, in-surgery real-time closed-loop navigation and post-surgery quantitative evaluation, and significantly improves the precision, repeatability and predictability of clinical effects of surgery.
Owner:BEIJING CHUNLIZHENGDA MEDICAL INSTR
Intraoperative low-field magnetic resonance intelligent navigation method based on preoperative high-field data guidance
PendingCN121242731ASurgical navigation systemsComputer-aided planning/modellingLesion mappingField data
The invention relates to the technical field of magnetic resonance imaging, in particular to an intra-operative low-field magnetic resonance intelligent navigation method based on preoperative high-field data guidance, which comprises the following steps: acquiring a high-field MRI image of a patient before an operation and extracting a three-dimensional segmentation mask and clinical features of a focus; adjusting according to the clinical features to obtain an intraoperative scanning protocol; and performing low-field magnetic resonance examination during the operation to generate an intra-operation navigation image, and marking focus information. Aiming at the problem that the accuracy of a focus image provided by an ultra-low field system in the operation process in the prior art is not enough, a high-field MRI image collected before the operation is introduced as a reference, scanning sequence parameters of the ultra-low field system used in the operation are dynamically adjusted based on clinical features embodied in the high-field MRI image, a better imaging effect is achieved, and meanwhile, the accuracy of the focus image provided by the ultra-low field system in the operation process is improved. Focus information is marked on the intraoperative navigation image based on the three-dimensional segmentation mask as prior information, so that more refined segmentation of focuses on the intraoperative navigation image is realized, and the surgical requirements are met.
Owner:SHANGHAI SOUNDWISE TECHNOLOGY CO LTD
Drainage device
ActiveCN223041603USurgical navigation systemsComputer-aided planning/modellingDrainage tubesReoperative surgery
The utility model relates to a drainage device. The drainage device comprises a drainage tube (1) and a supporting assembly, a first cavity (12) is formed in the drainage tube (1), and an opening (13) communicated with the first cavity is formed in the wall of the tail end (11) of the drainage tube; the supporting assembly comprises a supporting body (14) and a tracing component (16). The supporting body is arranged in the second cavity (15) of the drainage tube (1) and supports the drainage tube in the process that the drainage tube is implanted into the body. A concave part (161) for accommodating the tracing component is formed on the support body; the supporting assembly further comprises a sleeve which is arranged outside the supporting body and covers the supporting body and the tracing component. According to the drainage device, preoperative planning and intraoperative navigation can be carried out, the operation precision is improved, any appearance size of a traditional drainage tube is not changed, the drainage device is small in size, and the manufacturing and assembling process is simple.
Owner:KANGHUI MEDICAL INNOVATION
A kidney-cleared long-circulating near-infrared fluorescent probe and its preparation method and application
A renal-cleared, long-circulating near-infrared fluorescent probe, its preparation method, and applications. This renal-cleared, long-circulating near-infrared fluorescent probe utilizes a sulfonated calixarene derivative as a renal-clearing moiety and a cyanine dye derivative as a fluorophore, coupled via a click reaction. This probe exhibits broad spectrum compatibility with a variety of fluorophores and exhibits excellent water solubility, biocompatibility, rapid renal clearance, extended blood circulation time, and tumor targeting. As a fluorescent probe, it enables more precise non-invasive imaging of diseases and intraoperative navigation.
Owner:ZUNYI MEDICAL UNIVERSITY