24 results about "Surgical excision" patented technology

A method and apparatus for preparing tissue of interest in a patient for possible excision by surgery. In one embodiment, the method comprises the steps of: removing a biopsy sample from the tissue of interest; placing a magnetic marker at the biopsy site; performing a pathology analysis of the biopsy sample; and if the pathology analysis indicates that the tissue of interest should be removed, locating the tissue for surgery using a magnetic detection probe. In one embodiment, the marker comprises magnetic nanoparticles in a bioabsorbable matrix. A system for preparing tissue of interest in a patient for possible excision by surgery. In one embodiment, the system includes a magnetic marker and magnetic detection probe system.

The invention relates to a tumor and blood vessel three-dimensional space relation quantitative analysis method based on an enhanced CT image, and the method comprises the following steps: obtaining a thin-layer enhanced CT image, and carrying out the segmentation processing of the thin-layer enhanced CT image, and obtaining a tumor and blood vessel segmentation result; extracting a blood vessel center line from the segmentation result to generate a local plane, and reconstructing to obtain two-dimensional slices corresponding to each point on the blood vessel center line, including a blood vessel slice and a tumor slice; and based on the blood vessel section and the tumor section, determining an interaction area and calculating a wrapping angle. Compared with the prior art, the method has the advantages that the three-dimensional space relation between the tumor and the main blood vessel can be efficiently and accurately quantified, especially the wrapping angle can be calculated, and therefore more accurate and quantitative data can be provided for follow-up operation resection evaluation.

The present invention belongs to the technical field of immune cell culture, and specifically relates to a composition and kit for expanding tumor infiltrating lymphocytes, and an expansion method therefor. Provided is a composition for expanding tumor infiltrating lymphocytes for a trace amount of tumor tissue, i.e., a tumor biopsy sample, to perform the expansion of tumor infiltrating lymphocytes, which solves the problem that a large amount of a tumor tissue sample is required for tumor infiltrating lymphocytes, and is suitable for patients who cannot undergo surgical resection to obtain tumor tissue. In addition, by means of optimizing the combination and working concentration of antibody stimulants, a process flow for expanding tumor infiltrating lymphocytes on the basis of biopsy samples is established, such that the stemness of the expanded tumor infiltrating lymphocytes is maintained, and the killing ability is improved, thereby ensuring the anti-tumor efficacy after reinfusion into the body.

The present invention discloses a method for analyzing multiple epileptic seizures based on dynamic high-order directed network information flow, which belongs to the field of image analysis. It solves the problems that simple brain network analysis technology does not take time factors into account, existing brain network technology fails to capture high-order electrode propagation patterns, and the complexity of high-order matrices greatly affects the performance of similarity indicators. It mainly captures the interaction of information flows between electrodes at different hierarchical levels by fusing high-order information, effectively eliminates matrix redundant information based on the non-similarity index of singular value decomposition, and quantitatively compares the differences in seizure paths. Ultimately, it successfully tracks the different patterns of propagation paths of multiple epileptic seizures, providing a reference value for surgical resection of patients with focal epilepsy.

The invention relates to the field of automatic medical equipment, in particular to a device for automatically picking lymph nodes on gastrointestinal walls. The device for automatically picking up the lymph nodes on the gastrointestinal wall comprises an X-ray imaging device used for performing high-definition X-ray imaging on tissue subjected to biopsy or surgical excision so as to provide a high-resolution image; the target detection model is used for identifying the high-resolution image and acquiring the position information and the size of each lymph node; by training the deep neural network, the target detection model automatically identifies and locates lymph nodes in the medical image; and the mechanical arm receives the lymph node information sent by the target detection model and executes picking operation. According to the device for automatically picking up the lymph nodes on the gastrointestinal wall, dependence on experience of doctors can be effectively reduced, a homogenized and standardized picking mode is established, and clinical doctors are assisted in improving the sampling and processing level of specimens.

The invention relates to the technical field of near-infrared second-region organic dyes, in particular to an exosome-encapsulated near-infrared second-region xanthene J aggregate as well as a preparation method and application thereof. The near-infrared two-region xanthene J aggregate encapsulated by the exosome is composed of a targeted drug modified exosome and a near-infrared two-region xanthene dye LY, it is found that LY can form a stable J aggregate through self-assembly, the J aggregate is encapsulated in a targeted modified exosome, and an efficient and stable near-infrared two-region J aggregate nano diagnosis and treatment system can be obtained. The application of the drug is expected to solve the problems of incomplete surgical resection, obstruction of drug delivery by blood-brain barrier, poor traditional treatment effect and the like in current glioma treatment.

The invention discloses a rectal surgery system which comprises an infection isolation assembly, a drainage pump assembly and a drainage pump assembly, the infection isolation assembly is fixed to the intestinal wall and seals the intestinal tract, and in the physiological excretion process, excretion is conveyed out of the body through a closed pipeline of the drainage pump assembly of the assembly; the knife tackle supporting and pathological product capturing assembly is used for erecting the inner wall of the intestine, providing a working platform and space for a negative pressure knife tackle and establishing an intestinal negative pressure environment, capturing pathological products through overflow groove holes formed in a supporting plate of the knife tackle supporting and pathological product capturing assembly under the assistance of negative pressure, and positioning the distribution area of the pathological products; and the negative pressure knife tackle is mounted on the knife tackle supporting and pathological product capturing assembly and is used for non-invasive removal of the pathological products of the rectal tumor. Compared with an existing rectal tumor operation normal form, the operation system has the advantages that in the operation process, the rectum of the diseased region and nearby visceral organs do not need to be cut off, multiple complications such as function loss caused by human organ operation cutting off can be avoided, and great clinical value is achieved.

A minimally invasive therapeutic device for single-session ablation of cutaneous and mucosal lesions up to 1 cm in diameter is disclosed. The apparatus comprises an ultra-fine (0.2 mm) titanium micro-needle, guided by integrated impedance sensors to ensure accurate penetration depth, and a compact pulsed steam generator that delivers controllable steam (100–150 °C, 1–3 bar) directly into the lesion base. A built-in microsurgical camera provides real-time visualization of lesion borders, enabling precise alignment and confirmation of complete ablation. Modular tips permit safe access to both skin and cervical mucosa, while an ergonomic needle-height adjustment mechanism ensures targeted treatment of deep-seated tissue without harming surrounding healthy areas. This system overcomes the limitations of cryotherapy, laser ablation, and surgical excision by achieving full thermal desiccation and ashing of abnormal tissue in one session, reducing patient discomfort, lowering recurrence rates, and shortening recovery time.

The present invention discloses a tumor diagnosis method and system for generating a molecular spatial distribution map based on MRI, belonging to the technical field of image data processing. The method includes: constructing an MRI-pathology local matching data set; constructing a local MRI-generated pathology small map model by combining Transformer and GAN; constructing and verifying a molecular spatial distribution map. The present invention takes tissue pathology as a bridge, constructs a two-layer mapping relationship between MRI and molecular features, estimates global molecular features with local matching data, effectively utilizes existing clinical resources, and indirectly realizes the evaluation of the three-dimensional spatial distribution of molecular features at a low cost. The constructed model can perform pathological diagnosis on any region of the brain MRI sequence, helps to discover potential invasive regions of tumors, and provides a reference for defining the surgical resection range and planning treatment strategies for gliomas.

The application discloses a kind of clinical planning-oriented CT liver anatomical structure intelligent processing method and system, method includes: receiving CT image data, and the preprocessing operation of voxel resampling, gray standardization and direction correction is executed to CT image data;The inference of CT image data after pre-processing is carried out, and the blood vessel tree structure and liver segment segmentation result are obtained;Based on blood vessel tree structure and liver segment segmentation result, it is judged whether segmentation result satisfies the quality standard of clinical operation planning;If segmentation result satisfies quality standard, then using three-dimensional reconstruction algorithm generates the interactive three-dimensional grid model of liver, blood vessel and liver segment structure;Based on three-dimensional grid model, each liver segment volume, simulated surgical resection range, estimated future remaining liver volume and measured adjacent relationship of focus and key blood vessel are calculated, and structured analysis report for preoperative planning is generated. Utilize the embodiment of the application, the precision of liver anatomical structure segmentation and clinical applicability can be improved.

The invention relates to the technical field of medical equipment, in particular to a tumor minimally invasive surgery resection device which comprises an outer sleeve, the two ends of the outer sleeve are an operation end and an equipment end respectively, a bent telescopic pipe is arranged in the outer sleeve, a plurality of symmetrical transmission ropes are arranged in the bent telescopic pipe, and the bent telescopic pipe comprises a plurality of bent joints. The bending joint comprises a plurality of annular plates, a plurality of hinge lock assemblies are arranged on the sides, close to each other, of the adjacent annular plates, a driving assembly is arranged at the equipment end of the outer sleeve, and the driving assembly is in signal connection with a control system. The operation end of the outer sleeve is provided with a cutting assembly, and the equipment end of the outer sleeve is provided with an operation rod. The operation end of the outer sleeve is further provided with a collection assembly and a suction assembly. The active deformable tube body structure is optimally designed, an intelligent tissue recognition system is integrated to monitor the tumor cutting edge in real time, the operation precision and safety are improved, meanwhile, the operation process is simplified, the operation time is shortened, and the pain of a patient is relieved.

The utility model discloses a neurosurgery microscopic tumor taking forceps, which comprises a head part (1), a body part (2) and a tail part (3), the tail part (3) is arranged at the rear end of the body part, the head part (1) is arranged at the front end of the body part (2), the head part (1) is provided with a tumor taking spoon (11), the body part comprises a trunk body (21), a connecting part (22) and a handheld part (23), the trunk body (21) is connected with a handheld part (23) through a bent connecting part (22), a protruding part (230) is arranged on the outer side face of the handheld part (23), and a cylindrical protrusion (231) for preventing the tumor taking forceps from deforming is arranged on the inner side face, away from the tail, of the handheld part (23). The tumor can be effectively clamped, the difficulty of surgical excision of hard and tough tumors is reduced, and the hand fatigue caused by long-time holding of tumor taking forceps by an operator is effectively relieved.

In accordance with aspects of the inventive concepts, provided is a marker device, comprising: an elongate element; a needle disposed at a distal end of the elongate element; and at least one radiopaque marker element coupled to or disposed on at least a portion of an outer surface of the elongate element. The at least one marker can include radiopaque portions. The at least one radiopaque marker element can be or include a helical coil wrapped around a suture element. Also provided is a method of marking a surgical site comprising suturing a marker device into the surgical site. The method can include sewing or otherwise attaching the marker device to the soft tissue at boundaries of an excision site. Also provided is a method of making a marker device.

The invention discloses a clinical planning-oriented CT liver anatomical structure intelligent processing method and system, and the method comprises the steps: receiving CT image data, and carrying out the preprocessing operation of voxel resampling, gray level standardization and direction correction on the CT image data; reasoning the preprocessed CT image data to obtain a blood vessel tree structure and a liver segment segmentation result; based on the blood vessel tree structure and the liver segment segmentation result, whether the segmentation result meets the quality standard of clinical operation planning or not is judged; if the segmentation result meets the quality standard, generating an interactive three-dimensional grid model of the liver, the blood vessel and the liver segment structure by using a three-dimensional reconstruction algorithm; calculating the volume of each liver segment based on the three-dimensional grid model, simulating an operation excision range, estimating the volume of the future residual liver, measuring the proximity relation between a focus and a key blood vessel, and generating a structured analysis report for preoperative planning. According to the embodiment of the invention, the accuracy and clinical applicability of liver anatomical structure segmentation can be improved.

The invention relates to the technical field of medical image processing, in particular to a general surgery department acute abdominal disease operation planning system based on AI image analysis, which comprises an image data acquisition module, a focus feature extraction module, an ischemia analysis module, an operation scheme construction module and a diagnosis result generation module. According to the method, uniform expression of multi-source data in space is guaranteed through numerical fitting and registration of an image sequence, multi-angle extraction of pathological features is achieved by combining quantitative indexes such as intestinal wall thickness, orifice expansion and hydrops density, and systematic marks are formed through deep learning feature fusion. A potential ischemic area can be quickly identified under the condition of complex abdominal lesion, accurate definition of a lesion range is realized by utilizing perfusion indexes and continuous section screening, and a relationship between lesion length and anatomical space is further calculated, so that a quantitative basis is provided for an operation excision range and an anastomosis condition; deviation caused by subjective judgment is reduced, and the pertinence and the executability of a treatment scheme are improved.

This utility model discloses a surgical excision device, relating to the field of surgical instruments. It includes a handle with an L-shaped groove at its front end. Two shearing blades are laterally rotatably connected to the bottom surface of the L-shaped groove, and the bottom surface of the L-shaped groove has an elastic structure for opening the two shearing blades. By inserting the shearing blades into the body at the excision site, pushing the push plate forward moves the gate-shaped plate and two limiting blocks towards the tip of the shearing blades. Simultaneously, the two limiting blocks, through wedge-shaped engagement with the slope extrusion strip, move the two shearing blades closer together to cut off the tumor mass. The shearing blades are then removed, and the two support arms are flipped so that two gripping scoops are fixed to the tip of the shearing blades by a fixing structure. The two gripping scoops are then opened and closed to grasp the tumor mass into the elastic membrane of the gripping scoops and remove it. The entire operation is quick and convenient, avoiding the use of multiple instruments. Furthermore, the membrane design better protects the tumor mass during the grasping process, improving practicality.

The present disclosure provides methods and systems for personalized genetic testing of disease in a subject, in particular for identifying and tracking genetic mutations identified in an individual subject to monitor for cancer or for the spread or recurrence of the disease. In some embodiments, custom assays, including custom panels designed to target sequence data corresponding to both subject-specific loci and other loci known for cancer-causing or therapy resistance mutations, are designed based upon the sequencing of a screening biopsy sample. Such custom assays are then run on subsequently obtained tissue samples, such as tissue obtained from a surgical resection of a primary or metastatic tumor or from a lymph node biopsy. The subsequently obtained tissue samples can be taken from the subject at various time points after an initial screening biopsy to further allow for extended monitoring of the subject for spread or recurrence of the disease.

1. The name of the design product: electric snare handle. 2. The use of the design product: medical appliance for gastric polyp surgery. 3. The design features of the design product: in shape. 4. The picture or photo that best indicates the design features: front view.

Provided herein, in part, are selective delivery molecules their methods of use in the detection of cancer tissue and surgical excision of said cancer tissue.

The invention relates to the technical field of medical instruments, in particular to a skin tumor surgery resection device which comprises a placing box and further comprises a distraction mechanism arranged in the placing box and used for adjusting the distraction force of the device according to the lifting degree of the device; the moving mechanism is arranged on one side of the distraction mechanism, and the moving mechanism adjusts the traction force of the device according to the distraction force of the device. Through the distraction mechanism, when a medical worker pushes and pulls a handle, a connecting rope is wound and unwound on the surface of a first vertical roller to drive the first vertical roller to rotate, and the first vertical roller is fixedly connected with a rotating gear; the rotating gear rotates to be meshed with the moving rack, the moving rack is pushed to do linear motion in the sliding groove, the moving rack drives the supporting frame to ascend and descend through the connecting block, the skin is expanded or retracted, the force transmission direction of the connecting cable is changed through the pulley assembly, the labor-saving effect is achieved, and handle operation is convenient.

The invention relates to a tumor resection auxiliary evaluation method, which comprises the following steps: acquiring a CT image and carrying out segmentation processing to obtain a tumor and blood vessel segmentation result; extracting a blood vessel center line from the segmentation result to generate a local plane, and reconstructing to obtain two-dimensional slices corresponding to each point on the blood vessel center line, including a blood vessel slice and a tumor slice; based on the blood vessel section and the tumor section, determining an interaction area and calculating a wrapping angle; cT images and corresponding tumor lesions and blood vessel mask data are collected, tensors are constructed, wrapping angle data are combined, training is carried out based on a ResNet network and a CBAM module, and a resection evaluation model is obtained; and inputting the current CT image and the corresponding wrapping angle into the resection evaluation model, and outputting to obtain a resection evaluation classification result. Compared with the prior art, the method has the advantages that the intelligent workflow of automatic tumor vessel segmentation, wrapping angle calculation and resection evaluation can be realized, and more accurate and quantitative data support is provided for surgical resection evaluation.

The invention belongs to the field of optical system design and manufacturing, and relates to an endoscopic imaging system and method based on space-time parallax resolution. The four miniaturized imaging units are integrated in the aluminum shell to be fixed and protected, the tail end of each miniaturized imaging unit carries out power supply and information transmission through the flexible cable, and the probe part of the system is integrally formed. And then the probe is wrapped by a flexible polymethyl methacrylate shell, so that the probe structure and the cable are further protected. The endoscopic imaging system based on space-time parallax resolution is expected to reduce missed diagnosis of early lesions of a digestive system, so that the probability of canceration is reduced. In addition, the in-situ three-dimensional quantitative measurement can also assist the accuracy of surgical resection and biopsy.

The present invention discloses a surgical system for use with a surgical instrument in a surgical procedure performed on an anatomical organ. The surgical system includes at least one imaging device and control circuitry configured to identify an anatomical structure relevant to the surgical procedure based on visualization data from the at least one imaging device, recommend a surgical resection path for removing a portion of the anatomical organ using the surgical instrument, and present parameters of the surgical instrument based on the surgical resection path. The surgical resection path is determined based on the anatomical structure.

Disclosed in the present invention are an endoscopic ultrasonic image-based lesion excision risk evaluation method, system and apparatus, the method comprising: using an object detection model to perform object detection on an endoscopic ultrasonic image to obtain a first detection result and a second detection result; on the basis of the first detection result, cropping the endoscopic ultrasonic image to obtain a first target image and, on the basis of the second detection result, cropping the endoscopic ultrasonic image to obtain a second target image; using a semantic segmentation model to segment a landmark region in the second target image to obtain a third target image; detecting scale line segments in the first target image and, on the basis of the scale line segments, calculating a physical length corresponding to each pixel; extracting feature parameters of the endoscopic ultrasonic image, the feature parameters comprising a physical length feature parameter; and, on the basis of the feature parameters, evaluating a perforation probability. The present invention accurately predicts perforation risks during surgical excision, provides a solid basis for subsequent quantitative analysis, and improves the safety of gastrointestinal tumor surgery.