13results about How to "Realize highly sensitive detection" patented technology

The invention is suitable for the field of gas sensor detection, and provides a mixed potential type ammonia gas sensor and a preparation method thereof. The mixed potential type ammonia gas sensor comprises a layered nickel silicate sensitive electrode, a reference electrode and a solid electrolyte, the layered nickel silicate sensitive electrode and the reference electrode are positioned on the surface of the solid electrolyte; the layered nickel silicate sensitive electrode is prepared from three kinds of layered nickel silicate electrode slurry with different morphologies. According to the invention, the layered nickel silicate is used as the sensitive electrode, so that the response value to ammonia gas is obviously improved at room temperature; compared with an existing most advanced mixed potential type ammonia gas sensor, the high-temperature mixed potential type ammonia gas sensor has the advantage that the low-concentration response to ammonia gas can be remarkably improved at room temperature compared with other high-temperature mixed potential type ammonia gas sensors.

The application belongs to the field of optical fiber sensing, and particularly relates to a high-sensitivity optical fiber SPR traditional Chinese medicine active ingredient sensor and a manufacturing and using method thereof; the sensor comprises a core offset light injection area, a mode modulation and compression area and a coarse core light receiving area which are sequentially fused, the mode modulation and compression area is in three modes of a groove type of graded-index fiber, a taper spiral type of core offset fiber and a flat bottom partial sphere type of core offset fiber, gold films and target proteins are arranged on the mode modulation and compression area from inside to outside, an optical signal is injected into the mode compression and modulation area from the core offset light injection area, after modulation, the optical signal mode is concentrated and the light incidence angle is effectively modulated, the sensor sensitivity is greatly improved, transmission light contacts the gold films to generate an SPR effect, the target proteins are specifically combined with traditional Chinese medicine active ingredients, an SPR resonance valley moves, and specific detection of traditional Chinese medicine active ingredients is realized. The application solves the problems of low sensitivity and difficulty in specific detection of the current optical fiber SPR traditional Chinese medicine active ingredient sensor.

The application relates to a kind of cascade low-temperature single-photon detectors based on torsion semimetal materials, comprising: substrate, cascade structure and electrode;Wherein, the cascade structure is arranged on the substrate;The electrode is arranged on the cascade structure;The cascade structure is formed by the alternating stacking of dielectric layer and Dirac semimetal material;The outermost layer of the cascade structure from bottom to top and from top to bottom is the dielectric layer;The electrode includes a top gate electrode arranged at the top of the cascade structure and a plurality of source / drain metal contact electrodes arranged on the Dirac semimetal material.The beneficial effects of the application are: the Fermi level of the Dirac semimetal material used in the application is adjustable, the internal carrier concentration is controlled by the gate region, and the single-photon energy can excite to generate a photovoltage signal.

The application discloses a membrane sample injection ion funnel ionization source device and belongs to the technical field of mass spectrometry analyzers. The device comprises an ionization source cavity, the top of the ionization source cavity is provided with a vacuum ultraviolet lamp, and the bottom of the ionization source cavity is provided with a differential electrode; an ion repulsion electrode is arranged below the vacuum ultraviolet lamp, the ion repulsion electrode is arranged in parallel with the differential electrode, the ion repulsion electrode and the differential electrode are connected through insulating columns, the insulating columns are at least 3 and are perpendicular to the differential electrode, a direct current transmission electrode group is arranged on the inner side of the insulating columns, a tubular membrane is arranged on the outer side of the insulating columns, and the tubular membrane is arranged in position correspondence with the direct current transmission motor group; and an ion funnel device is arranged below the direct current transmission electrode group. The application proposes a membrane sample injection ion funnel ionization source based on vacuum ultraviolet photoionization technology, and combines membrane sample injection enrichment technology and ion funnel ion focusing technology, so that the detection sensitivity of the instrument is greatly improved.

The invention discloses a preparation method and application of an electrochemical biosensor based on a self-protection palindromic DNA (deoxyribonucleic acid) nanosphere. The electrochemical biosensor comprises an HP-trigger, a target miRNA (micro ribonucleic acid) and a self-protection DNA palindromic nanosphere core structure. The DNA nanosphere is of a three-dimensional spherical structure formed by four single-stranded DNAs through complementary base pairing, the three single strands of SEP-Sa, SEP-Sb and SEP-Sc contain 12 nt palindromic cohesive ends and 15 nt single-stranded arms, the single strand of HP-Sc contains 35 nt prolonged hairpin structures, the structural stability is enhanced through a self-protection mechanism of a palindromic sequence, and structural dissociation triggered by target miRNA is achieved. The target miRNA is combined with an HP-Sc hairpin structure to trigger conformational change, release complementary chains and dissociate palindromic nanospheres, and exposed DNA sites are combined with MB to generate electrochemical signals, so that a novel tool is provided for early diagnosis of tumors.

The application discloses a kind of track traffic defect detection methods based on multi-source perception and causal decoupling. By synchronously acquiring high-resolution RGB image and structural micro-vibration signal of track inspection scene, four-dimensional perception data field containing component dynamic mechanical response characteristics is constructed, and dynamic mechanical response field representing the stiffness of structure at each spatial position is generated;Instance segmentation is performed on the static topography component in the RGB image and the four-dimensional data field, and a topological relationship graph is constructed with components as nodes and functional coupling relationships as edges;According to the topological relationship graph, double abnormal reasoning at node level and edge level is performed, and combined with generative deduction based on causal decoupling and cross-modal topological consistency verification, the final comprehensive defect judgment result is generated.The application improves the recognition accuracy and robustness of track traffic defect detection on subtle defects such as micro-looseness and functional disorder.

The application discloses a kind of amoxicillin concentration detection methods based on optical fiber, using device includes: broadband light source, single-mode optical fiber, polarization controller, flow cell, TFBG-SPR sensor and spectrum analyzer.First by broadband light source to emit the light of wavelength range between 1420~1620nm, the polarization state of light is adjusted to P state by polarization controller, then through polydopamine, polyaniline and beta-lactamase layer-by-layer modified sensing probe, finally form spectrum on spectrum analyzer.Bio-identification film based on beta-lactamase modified on the surface of optical fiber will be combined with amoxicillin molecule to cause the change of refractive index, and the drift of transmission spectrum is shown on spectrum analyzer, the relationship between different amoxicillin solution concentration and transmission spectrum drift is compared, to realize the rapid, accurate, trace detection of amoxicillin concentration.The application provides a new method for the measurement of amoxicillin and other beta-lactam antibiotics concentration, which has simple structure, high accuracy and fast response, and has very important potential application value in environmental pollution and food health monitoring.

The invention discloses a tungsten-based oxide composite material and a preparation method thereof, a trihydroxy dibutanone gas sensor and application, the tungsten-based oxide composite material is tungstate-tungsten oxide, and tungstate and tungsten oxide form a heterostructure; the tungsten oxide is W18O49; the tungstate is MWO4, and M is selected from at least one of Fe, Co, Ni, Cu and Sn. The successful design of the material and the preparation of the sensor provide a new thought for the detection of 3H-2B, and the epitaxial growth method can also be popularized to the fields of catalysis, energy and the like, and has extremely high reference value.

The invention relates to the technical field of visual inspection, in particular to a quality inspection system for repairing surface defects of a gel finished product based on image recognition, which comprises a deformation induction imaging module for applying controllable micro-pressure deformation to a gel sample according to the projected area and hardness grade control pressure of the gel sample, capturing a dynamic sequence image of the deformation process, and outputting the dynamic sequence image; surface microcracks are detected; the characteristic analysis module is used for extracting response characteristics of a defect area from the dynamic image sequence, including distinguishing free impurities from fixed impurities according to a relative displacement track, positioning bubble defects by identifying a stress birefringence ring and detecting an opening behavior of surface microcracks in a deformation process; calculating a relaxation time constant ratio and a stress concentration factor of the defect area and the normal area, and evaluating the interface bonding strength; the repair matching module is used for determining a repair feasibility grade according to the interface bonding strength and carrying out self-adaptive correction on the process parameters; and then detecting a verification module, and comparing the variation of the stress concentration factors before and after repair to judge a repair result.

The invention discloses a biological-nano composite dissolved oxygen sensor, a preparation method thereof, and a dissolved oxygen detection system and method.The biological-nano composite dissolved oxygen sensor comprises silicon dioxide nanoparticles, the outer walls of the silicon dioxide nanoparticles are of a porous structure, and oxygen-sensitive protein is adsorbed in through holes in the outer walls of the silicon dioxide nanoparticles; a donor dye CY3 and an acceptor dye CY5 are loaded on the outer wall of the silicon dioxide nanoparticle, a hydrophilic anti-biological-pollution coating is arranged on the outer side of the silicon dioxide nanoparticle, the donor dye CY3, the acceptor dye CY5, the silicon dioxide nanoparticle and the oxygen-sensitive protein are all wrapped in the hydrophilic anti-biological-pollution coating, and the hydrophilic anti-biological-pollution coating is coated with the donor dye CY3, the acceptor dye CY5, the silicon dioxide nanoparticle and the oxygen-sensitive protein. The sensor, the detection system and the detection method can realize real-time, high-sensitivity, high-precision and low-cost detection of the dissolved oxygen of the water vapor system of the thermal equipment.

The invention relates to an electrochemical aptamer sensor and a method for detecting ochratoxin A. The electrochemical aptamer sensor comprises: a working electrode; the invention relates to a CRISPR / Cas12a reaction system. The invention also comprises a method for detecting ochratoxin A by using the electrochemical aptamer sensor. The method comprises the following steps: extracting, filtering and diluting a sample to obtain a sample solution for detection; the sample solution is added into a CRISPR / Cas12a reaction system; enabling a reaction system to be in contact with an MB-labeled single-stranded DNA modified gold electrode; and detecting the current signal change on the surface of the electrode by adopting an electrochemical method, and comparing and analyzing the detection result with the standard curve to obtain the concentration of the ochratoxin A in the to-be-detected object. According to the method, high-sensitivity detection of the micromolecular mycotoxin is realized, the detection process is simple to operate, the reaction time is short, no complex instrument is needed, and the method has good specificity and anti-interference capability and can be suitable for quantitative analysis of the ochratoxin A in a real grain sample.

The application discloses a kind of multi-parameter wearable smart optical fiber sensing systems, the system includes: fluorescent sensing patch, for detecting target by fluorescence reaction, including biosensor, biosensor is used to react with target and generate fluorescence signal;Data glove, for real-time monitoring finger joint bending state and realizing gesture recognition, including glove and the multiple fiber bending sensors of joint part of being attached to glove, fiber bending sensor reflects finger bending degree in real time by light intensity change, and exports multidimensional light intensity signal;Wearable fiber detection meter is connected with fluorescent sensing patch, data glove, for collecting and analyzing fluorescence signal and bending signal.The multi-parameter wearable optical fiber intelligent sensing system has multi-channel, full-automatic intelligent detection and analysis capability, can simultaneously provide fluorescence, gesture bending and environmental temperature and humidity and other multi-physical and chemical parameters Real-time monitoring and analysis services provide powerful technical support for the application of each field.

The application relates to the field of flexible functional materials and human-computer interaction technology, and discloses a preparation method of a trehalose-enhanced anti-freezing conductive hydrogel fiber and application of the trehalose-enhanced anti-freezing conductive hydrogel fiber in intelligent gloves. The hydrogel is an acrylamide / polyvinyl alcohol double-network structure, and trehalose and lithium chloride are introduced. The trehalose forms a reversible hydrogen bond network with polymer chains through multiple hydroxyl groups, and the lithium chloride exists in the form of a hydrated ion in network pores to form an ion conductive path. The hydrogel forms a continuous linear fiber structure, the cross-sectional diameter is 0.3-2.5 mm, the flexibility is maintained at an environment of-20 DEG C, the conductivity retention rate is greater than or equal to 80%, the elongation at break is greater than or equal to 1000%, and the mechanical hysteresis is less than or equal to 5%. The application solves the problems of low-temperature failure and difficulty in fiberization of existing conductive hydrogels, and can be applied to flexible strain sensors, intelligent gloves and remote mechanical control systems.