114 results about "Supermolecule" patented technology

This invention provides an organic ferroelectric eutectic material, its preparation method, and its applications, relating to the field of ferroelectric materials technology. The organic ferroelectric eutectic material constructs a crystal system with "rigid constraint and flexible adaptation coexisting, dipole order and controllable polarization synchronously" through "molecular selection-supramolecular assembly-crystal structure regulation," achieving a synergistic effect of high Curie temperature, strong polarization characteristics, and excellent flexibility. The preparation method of the organic ferroelectric eutectic material utilizes a simplified "solvent dissolution-solvent evaporation" process, leveraging the mediating effect of the solvent to promote the supramolecular self-assembly of donor and acceptor molecules. This achieves the preparation of an organic ferroelectric eutectic material possessing both high Curie temperature, strong polarization characteristics, and excellent flexibility. The preparation method has multiple advantages, including "stable process, low cost, and suitability for large-area processing," making it a simple, efficient, and universally applicable preparation method suitable for large-scale industrial production.

The application discloses a supramolecular lotus leaf peptide-narcotic alkaloid Pickering emulsion as well as a preparation method and application thereof. The water phase of the supramolecular lotus leaf peptide-narcotic alkaloid Pickering emulsion is a purified lotus leaf peptide aqueous solution, and the oil phase is camellia seed oil loaded with narcotic alkaloids. The camellia seed oil not only serves as a fat-soluble carrier to improve the solubility of the narcotic alkaloids, but also has nursing effects due to the unsaturated fatty acids, vitamin E and phytosterols contained therein. The supramolecular assembly technology is used to mediate the lotus leaf peptide and the narcotic alkaloids to form high-performance emulsified particles, to replace synthetic surfactants to stabilize the Pickering emulsion, and to construct a natural emulsion system with high emulsification efficiency, high stability and high performance, so that the performance and the nursing effect of the emulsion are optimized.

This invention relates to a hyaluronic acid composite hydrogel based on the supramolecular self-assembly of natural molecules and its preparation method, belonging to the field of gel formulation technology. The invention first involves the self-assembly of specific natural molecules or their derivatives possessing hyaluronidase inhibitory and anti-inflammatory activities into stable supramolecular self-assemblies through intermolecular non-covalent interactions. Subsequently, this supramolecular self-assembly is combined with hyaluronic acid through various interactions such as physical entanglement, hydrogen bonding, van der Waals forces, or appropriate chemical cross-linking to construct a composite hydrogel with a uniform internal structure and stable performance. This invention not only achieves long-term, controllable sustained release of natural active ingredients in the gel through supramolecular loading, continuously inhibiting hyaluronidase activity and local inflammatory responses, but also avoids the residual risks associated with high dosages of traditional chemical cross-linking agents, ultimately obtaining a high-quality product that meets the appearance and performance requirements of medical hyaluronic acid gels.

This invention provides a Panax notoginseng-Paris polyphylla supramolecular complex, its preparation method, cosmetic products, and applications. The Panax notoginseng-Paris polyphylla supramolecular complex is a complex formed by non-covalent bonding of Panax notoginseng extract (as the host molecule) and Paris polyphylla extract (as the guest molecule), with the host molecule encapsulating the guest molecule structure. The Panax notoginseng-Paris polyphylla supramolecular complex of this invention not only improves the water solubility of Paris polyphylla extract but also increases its skin permeability and reduces its cytotoxicity. The preparation method of this invention utilizes the synergistic effect of the active ingredients, resulting in strong compatibility and synergistic efficacy. It also slows down the release time of the active ingredients, extends their shelf life, and features a simple and easy-to-control process, stable granulation effect, and low production cost.

The present application provides a coal gas fermentation level ultra-deep purification system and method based on cracking-precision screening-flow directional regulation, belonging to the technical field of coal gas deep purification and resource utilization. The method is to take coal gas through the cross-media synergistic cracking unit, the supramolecular biomimetic MOFs intelligent adaptive screening unit, the PN / A-Candida utilis metabolic flow precision regulation unit and the full-element grading resource recovery unit in turn, and is controlled by the digital twin-blockchain carbon footprint traceability and intelligent regulation PLC intelligent control system, so as to achieve the purpose of coal gas purification and SCP production. The present application first constructs a five-unit closed loop system, achieving the ppb level synchronous removal of five types of key pollutants in coal gas; through the multi-unit synergistic mechanism, the purification efficiency is improved by more than 20%, the energy consumption is reduced by 40%, the resource utilization efficiency is greatly increased, the resource recovery yield reaches 45%, and the benign cycle of full coverage of purification cost and profit is realized.

Nanocomposites comprising nanoparticles, small molecules, and block copolymer (BCP)-based supramolecules are provided. The nanoparticles, small molecules, and BCP-based supramolecules self-assemble into a plurality of nanosheets that form a multilayer nanocomposite. The nanoparticles, small molecules, and BCP-based supramolecules can be Zr02, 3-pentadecylphenol (PDP), polystyrene-b-poly(4-vinylpyridine) block copolymer (PDP) 1, respectively. b A method of producing a nanocomposite by contacting nanoparticles, small molecules, and BCP-based supramolecules with a solvent and drying to remove the solvent to allow self-assembly is also provided. The nanocomposites provided herein can be used as a barrier material against volatile organic compounds, water, oxygen, or electrons, and can be used as a coating on various substrates and as a packaging material, or as an optical material.

This invention discloses a method for synthesizing potassium 4-methoxysalicylate based on supramolecular-assisted methylation, belonging to the field of organic synthesis technology. The process is based on supramolecular chemistry principles and includes the following steps: (1) Preparation of a macrocyclic host molecule-methylating agent complex loaded with a methylating agent: The macrocyclic host molecule and the methylating agent are reacted at pH 7-9 and 25-40℃ to form a complex solution; (2) One-pot preparation of the target product: 2,4-dihydroxybenzoic acid is salted with potassium hydroxide, potassium carbonate is added, and the above complex solution is added dropwise. A selective methylation reaction is carried out at 55-65℃. After the reaction is complete, post-treatment yields the product. This invention utilizes the molecular recognition function of the macrocyclic host to achieve highly selective methylation of the 4-hydroxyl group under mild conditions. This process has the advantages of simple operation, high safety, low waste, and recyclable host molecules. The yield of potassium 4-methoxysalicylate can reach over 85%, and the purity exceeds 99.0%.

The application discloses a kind of multilayer nanostructure hemostatic powder and preparation method thereof, belong to the field of biomedical hemostatic material.To solve the problem of insufficient mechanical strength of existing silk fibroin-polyphenol hemostatic material, the silk fibroin solution is mixed with regenerated chitin nanofiber solution in proportion, and tea polyphenol solution is added dropwise to induce co-assembly and gelation, and the powder is prepared by washing, freeze-drying and grinding.The powder can quickly absorb water and self-gel after contacting with blood, and form a stable three-dimensional network hydrogel within a few seconds.The regenerated chitin nanofiber guides the formation of hierarchical nanostructure of silk fibroin through supramolecular interaction, significantly enhances the mechanical strength and adhesion, while tea polyphenol provides antibacterial, antioxidant and procoagulant functions.The hemostatic powder of the application has the functions of rapid hemostasis, strong adhesion in wet state, resistance to flushing and promotion of wound healing, and is suitable for various acute bleeding scenarios.

The application belongs to the technical field of wound dressings, and discloses a water-based gel dressing with antibacterial and scar prevention effects and a preparation method, wherein 3-fluoro-4-carboxyphenylboronic acid is introduced to graft chitooligosaccharide, a large number of catechol structures in tannic acid solution are combined with the phenylboronic acid bond to form a dynamic boron ester bond, and a network gel structure is formed by responding to the supermolecular forces such as hydrogen bonds, wherein the boron ester bond can be broken in response to the high ROS level of the wound microenvironment and the acidic environment caused by bacterial infection, so as to efficiently release celecoxib, a selective non-steroidal anti-inflammatory drug of cyclooxygenase-2, and the liposome of verteporfin is limited in volume and stays in the dressing for a longer time, so that the sustained and stable release can be maintained in the whole wound healing process, thereby achieving the effects of on-demand inflammation regulation and long-acting mechanical response regulation.

This invention discloses an EGCG supramolecular compound with antioxidant, liver-protective, and fat-reducing effects, its preparation method, and composition. The supramolecular compound is formed by non-covalent bonding between epigallocatechin gallate (EGCG) and ligand molecules containing trimethylamine and carboxyl groups; the supramolecular compound has a co-amorphous structure; the ligand molecules containing trimethylamine and carboxyl groups are betaine, ergothioneine, or L-carnitine. This invention can solve the problems of low stability and bioavailability of EGCG. It can significantly improve the solubility of EGCG and its ligands, including betaine, L-carnitine, and ergothioneine, reduce the hygroscopicity of EGCG and its ligands, including betaine, L-carnitine, and ergothioneine, and enhance the stability and bioavailability of EGCG and its ligands, including betaine, L-carnitine, and ergothioneine.

A conducting composition includes a topological polymer (e.g., a polyrotaxane polymer) and poly(3,4-ethylene-dioxy thiophene):polystyrene sulfonate (PEDOT:PSS). Devices may include a conducting layer including the conducting compositions, e.g., a device comprising a conducting layer, wherein the conducting layer includes a polyrotaxane polymer and a PEDOT:PSS array. The devices are useful in bioelectronics, including high-resolution electrophysiological monitoring of deformable tissues and localized neuromodulation for high-precision control of individual muscle activities.

This invention provides a supramolecular fluorescence sensing array and its application in detecting five tyrosine kinase inhibitors, belonging to the field of analytical chemistry detection technology. The supramolecular fluorescence sensing array is composed of three supramolecular fluorescent probes: 2NR@Q[8], 2AO@Q[8], and APFG@Q[8]. This invention uses a supramolecular fluorescence sensing array composed of three supramolecular fluorescent probes: 2NR@Q[8], 2AO@Q[8], and APFG@Q[8]. By utilizing the cross-fluorescence response signals generated by this supramolecular fluorescence sensing array for five TKIs, combined with classical pattern recognition algorithms, it is possible to perform qualitative and quantitative detection of five TKIs: GEF, EH, LD, AD, and DAC. Moreover, this supramolecular fluorescence sensing array has good anti-interference properties, and serum samples have demonstrated that the supramolecular fluorescence sensing array constructed in this invention can simultaneously analyze five TKIs in complex systems. Therefore, this invention provides a new method for detecting tyrosine kinase inhibitors, which is more intuitive and convenient than traditional detection techniques.

This invention provides a high-purity pyrazole trace metal ion ultrafiltration-impurity trapping synergistic impurity removal system and method, relating to the field of deep purification technology for electronic chemicals. The method first constructs a supramolecular trapping model based on steric hindrance, utilizing the coordination specificity of functionalized ionic liquids to induce trace metal ions to assemble into nanoscale micelle clusters under isopotential conditions, solving the problems of solute damage and ion back-migration contamination in traditional purification processes. Then, a two-stage synergistic mechanism of chemical complexation and physical sieving is employed, utilizing a surface-modified submicroporous composite membrane to achieve efficient retention of impurity clusters in the organic phase system through size exclusion effect. Finally, dynamic differential pressure compensation and quality self-judgment are performed based on feedforward-feedback dual closed-loop control logic, outputting a purified solution with high purity assurance and intervention strategies. This invention effectively improves the selectivity and stability of the impurity removal process, achieving the ultrapure preparation of electronic-grade pyrazole.

The application belongs to the field of natural product extraction and cosmetic raw materials, and discloses a preparation method and application of a composition containing asiaticoside-paeoniflorin, which comprises two key and functionally different stages: ① extraction stage: using asiaticoside as an extraction aid and using propylene glycol as a complex medium, efficiently dissolving and forming an "asiaticoside-paeoniflorin" supramolecular complex; ② complexing and stabilizing stage: using glycerol as a stabilizer to maintain the long-term kinetic stability of the formed supramolecular complex and prevent its dissociation and aggregation. The method solves the technical problem that the extraction rate and stability of paeoniflorin are difficult to be considered simultaneously in the field by functional division of extraction and stabilization, and the composition containing asiaticoside-paeoniflorin obtained finally has excellent soothing performance, not only rapid effect, but also persistent and stable soothing protection effect, which can effectively resist and repair the influence of external stimulation on the skin.

The present application relates to a kind of high-efficiency targeted penetration supermolecular oil-tea camellia seed oil and its preparation method and application, the supermolecular oil-tea camellia seed oil is to use palmitoyl tripeptide-1 and the specific interaction of tea saponin in oil-tea camellia seed oil constructs hydrogen bond and π-π stacking double action ordered self-assembly supramolecular system, the supramolecular has water oil amphiphilic structure characteristics, can be spontaneously emulsified, realize targeted delivery and slow-release balance, simultaneously avoid the skin irritation problem caused by adding emulsifier;And based on the amphiphilic characteristics of supramolecular core structure, it can be used to simultaneously adapt oil-soluble, water-soluble skin care formulations, respectively adapt polar and non-polar functional components, break through the penetration limit problem of traditional single carrier, greatly widen the application scene of oil-tea camellia seed oil in cosmetic field.

This invention provides a method and apparatus for preparing sodium ferrochlorophyllin using green organic acid-assisted membrane separation, relating to the fields of chemical separation and pharmaceutical raw material refining. The method first utilizes a green organic acid to construct a supramolecular micelle system, inducing high monomer-level dispersion of chlorophyllin molecules through a hydrogen bond network, thus solving the problem of hydrophobic aggregation in an aqueous environment. Then, an electrocoupled ceramic membrane reactor is employed, utilizing the physical confinement effect of nanopores to force microscopic deformation of the porphyrin ring, combined with a transmembrane alternating pulsed electric field to achieve targeted complexation of iron ions, overcoming the high energy barrier of steric hindrance in central ion replacement. Finally, based on a constant-volume cross-current dialysis and reverse osmosis coupling mechanism, macromolecular products are distinguished from small-molecule impurities, achieving closed-loop circulation of the organic acid solvent and precise product purification. This invention effectively solves the bottlenecks of active site masking and membrane fouling, significantly improving preparation efficiency, product purity, and the greening level of the production process.

Provided is use of a glyconanomaterial for inhibiting a DNA polymerase. The glyconanomaterial is generated by means of dry heating of a saccharide, and the glyconanomaterial comprises a graphene-like nanosheet and the saccharide, wherein the graphene-like nanosheet comprises a carbonization product of at least a part of the saccharide, and the graphene-like nanosheet and the saccharide are combined to form a cross-linked supramolecular structure. The glyconanomaterial can be applied to a hot-start polymerase chain reaction, thereby improving the sensitivity and specificity of the reaction.

The application discloses a phenylpyridine salt derivative G, a room-temperature phosphorescent supramolecular gel and a preparation method and application thereof. The preparation method of the room-temperature phosphorescent supramolecular gel comprises the following steps: taking Cucurbit[8]uril (CB[8]) as a host, a phenylpyridine salt derivative containing a urea-based pyrimidone (UPy) quadruple hydrogen bond site as a guest, self-assembling a supramolecular assembly phosphorescent material in a 1:2 molar ratio in an aqueous solution; and introducing the assembly into a polyvinyl alcohol (PVA) matrix to obtain a humidity-responsive room-temperature phosphorescent supramolecular gel. The assembly and the supramolecular gel both present phosphorescent emission at room temperature. Under the dual constraints of macrocycle limitation and multiple hydrogen bonds on the phosphorescent molecules, the phosphorescent intensity and lifetime of the supramolecular gel are greatly enhanced compared with the assembly. Meanwhile, the phosphorescent intensity and the light-emitting color of the supramolecular gel change with the water content of the gel or the environmental humidity, realizing a visual response from green to blue, and the supramolecular gel can be applied to humidity sensing, anti-counterfeiting and information encryption.

The application discloses a mussel-mimic bacterial-responsive injectable hydrogel and a preparation method and application thereof, and belongs to the technical field of biological medicines. The hydrogel is composed of a mussel-mimic viscous hydrogel support and a bacterial response agent; the viscous hydrogel support is QCS-EC, which is formed by non-covalent combination of quaternary ammonium chitosan QCS and epigallocatechin gallate EGCG; and the bacterial response agent is a supramolecular nanometer cross-linking compound TEBox-B 12， which is self-assembled by hydrogen bonds and electrostatic interactions. 12 H 12 2‑ The hydrogel of the application has NIR-II photothermal and photodynamic antibacterial treatment functions, can realize efficient killing of bacteria in deep tissues, has high adhesion, good biocompatibility and injectability, is convenient and applicable, can provide a good healing environment for a wound, promotes fibroblast proliferation and migration, accelerates wound tissue regeneration and healing process, and reduces scar formation.

This invention provides a method for extracting Sapindus mukorossi saponins using a supramolecular solvent, relating to the field of plant component extraction technology. The method includes the following steps: (1) dissolving the amphiphilic compound in ethanol or acetonitrile, adding water, vortexing, centrifuging, and collecting the upper layer to obtain the supramolecular solvent; (2) drying and pulverizing Sapindus mukorossi, adding the supramolecular solvent and cellulase, and extracting crude saponins using electric field-mediated super-dynamic crushing technology; (3) adsorbing the crude saponins onto a column using resin under oscillation; after washing, eluting with an aqueous ethanol solution under oscillation gradient, and drying to obtain Sapindus mukorossi saponin powder; (4) dissolving the powder in water and transferring it to a gas magnetic stirring foaming device to collect the foam, defoaming with ultrasound to obtain a refined saponin aqueous solution, and evaporating and concentrating to obtain Sapindus mukorossi saponin refined powder. This invention uses an electric field-mediated super-dynamic crushing composite supramolecular solvent, supplemented by oscillation gradient column method and gas magnetic stirring foaming device, which can extract Sapindus mukorossi saponins with higher purity in a short time.

The present invention provides a supramolecular hot melt adhesive. The present application also provides a method for preparing a supramolecular hot melt adhesive, comprising the steps of: A) dissolving a diol oligomer or diamine oligomer in a solvent, and reacting the mixture with diisocyanate under the action of a catalyst to obtain an initial reactant; B) mixing 2-amino-4-hydroxyl-6-methylpyrimidine, the initial reactant and a solvent for reaction; C) reacting the reactant obtained in step B) with a multifunctional crosslinking agent to obtain the supramolecular hot melt adhesive. The preparation method of the present invention constructs a supramolecular material with excellent strength, toughness and self-healing ability by a synergistic effect of multiple hydrogen bonds between carbamate or ureido group and pyrimidine group. The effective control of performance of materials can be realized by changing the chemical composition of supramolecular arms, the content of single-capping agent and the functionality of cross-linking agent.

This invention relates to the field of adhesive technology, specifically to an interface-stabilizing adhesive for silicon anodes and its preparation method. The adhesive comprises curcumin-modified silicon-containing waterborne polyurethane-acrylate, a terpolymer, and a multifunctional monomer, wherein the mass ratio of the curcumin-modified silicon-containing waterborne polyurethane-acrylate, the terpolymer, and the multifunctional monomer is 3-5:1-2:1-1.2. The curcumin-modified silicon-containing waterborne polyurethane-acrylate is synthesized using acrylate and γ-methacryloyloxypropyltrimethoxysilane as modifiers and curcumin as a chain extender via an interpenetrating polymer network method. Through chemical bonding such as grafting and crosslinking, and supramolecular interactions such as hydrogen bonding and coordination, an intelligent network integrating elastic buffering, rigid support, interface passivation, self-healing, and ion conduction is constructed. After cycling, the electrode thickness expansion rate is controlled to <40%, with no macroscopic cracks and high electrode peel strength retention.

The application discloses a kind of block copolymer and its preparation method and application, the application designs and synthesizes a kind of block copolymer mPEG-PLG-COOH-CD, utilize the host molecule β-CD with guest molecule IDO-1 inhibitor (such as Epa) and Pt class chemotherapy drug (such as cisplatin) with large cavity structure, by hydrophilic and hydrophobic interaction, host-guest recognition, coordination effect common assembly into supramolecular nanomedicine.Supramolecular nanomedicine simultaneously carries Pt class chemotherapy drug and IDO-1 inhibitor.Under the action of weak acid in tumor cell, nanomedicine swells, expose drug, and high concentration of Cl- will destroy the non-covalent bond force inside nanomedicine, quickly release chemotherapy drug and IDO-1 inhibitor, while activating chemotherapy and immunotherapy, realize the efficient combination of two kinds of therapy.In situ activation of chemotherapy not only directly kills cancer cells, but also activates the anti-tumor immunity of body.

This invention relates to the field of supramolecular copolymer hydrogel technology, specifically to a high-strength and tough supramolecular hydrogel with tunable interfacial hydration properties, its preparation method, and its applications. This invention uses N-acryloylaminourea (NASC) monomer and a sulfonate-containing monomer (lubricating molecule) as raw materials, and adds a photoinitiator. A prepolymer solution of an organic solvent and water mixture is prepared using the dehydrogenation effect of an organic solvent. Crosslinking polymerization is carried out under ultraviolet light irradiation to obtain a supramolecular hydrogel. Then, water equilibrium is achieved to obtain a high-strength and tough supramolecular hydrogel with tunable interfacial hydration properties. The high-strength and tough supramolecular hydrogel prepared by this invention possesses high water content, excellent lubrication properties, mechanical properties, structural stability, and long-term service reliability, exhibiting excellent comprehensive performance and meeting the synergistic requirements of multi-dimensional material performance in complex engineering scenarios or biomedical fields.

The application discloses a method for directional construction of eugenol-based supramolecular co-crystal system and application of the product, and belongs to the field of agricultural chemistry and supramolecular crystal engineering technology. The method comprises the following steps: selecting eugenol as a hydrogen bond donor molecule through rational molecular design, selecting nicotinamide or 2-pyridinecarboxylic acid as a co-crystal ligand according to the quantitative screening standards of hydrogen bond acceptor strength (pKa value), molecular geometric length and specific functional groups, dissolving the two in a mixed solvent with a specific dielectric constant range at a 1:1 molar ratio, and obtaining a supramolecular co-crystal product with a clear structure through programmed temperature uniform cooling crystallization, aging and drying. The product has stable crystal structure, pH-responsive release characteristics and slow-release performance better than that of a physical mixture. The product is added to urea at an addition amount of 0.5% to 5.0%. The application realizes directional construction of co-crystals from empirical screening to rational design, structure control and performance prediction, and provides a reliable material platform for nitrogen fertilizer efficiency.

This invention belongs to the interdisciplinary field of polymer materials and supramolecular chemistry, specifically relating to a polyurethane slip-ring crosslinked network elastic material with a slip-ring effect. The invention uses a macrocyclic molecule with oxetane-functionalized side groups as the cyclic component of a rotaxane. Through host-guest inclusion interactions, it forms a rotaxane polymer with the linear backbone, followed by a ring-opening crosslinking reaction of the oxetane groups, constructing an interpenetrating network structure that combines a three-dimensional covalent network with a supramolecular slip-ring effect. Under mechanical stimulation, this material dissipates energy through the relative slippage of the ring molecules along the backbone, exhibiting high resilience and wide-temperature-range stability. It can be applied in fields such as flexible electronics, wearable devices, and high-performance damping materials.

This invention discloses a high-strength, recyclable 3D-printable supramolecular eutectic gel, its preparation method, and its applications. The comprehensive mechanical properties of this invention far surpass those of existing similar gel materials, and are even comparable to some traditional structural polymers, completely breaking through the performance bottleneck of traditional eutectic gels where strength increases but toughness decreases. This invention employs a one-step photopolymerization process, requiring no chemical crosslinking agents, resulting in a short process flow, rapid reaction, low raw material costs, and environmental friendliness. It can be directly adapted to DLP / SLA photopolymerization 3D printing technology, enabling the rapid fabrication of complex customized structures such as lattices and biomimetic spiderwebs, overcoming the limitations of traditional eutectic gel processing methods and achieving a deep integration of material innovation and large-scale manufacturing processes. The gel material of this invention possesses a significant strain rate strengthening effect, effectively providing impact protection for fragile items such as glass and eggs in all scenarios, and has extremely high industrialization value in the fields of aerospace energy-absorbing components and personal protective equipment.

Disclosed is a supramolecular polyhedron comprising 12 identical macrocyclic molecules wherein the macrocyclic molecules interact via 144 C-H hydrogen bonds, including 24 [C-H... F], 48 [C-H... O], and 72 [C-H... Pi]. A supramolecular assembly, a composite system, a crystalline material, and a porous material are also disclosed. The invention further discloses application of the supramolecular polyhedron, the supramolecular assembly and the composite system. Further, the invention discloses a preparation method.

The application discloses a two-dimensional nanochannel membrane based on regulation of a molecular encapsulation technology, preparation and application, and belongs to the technical field of nanofiltration membrane preparation. The application constructs a graphene oxide membrane based on a method of intercalating by subjecting supramolecular encapsulation of guest metal ions, specifically, first, cross-linking modification is performed on a base film so that a GO selection layer on the base film has good dispersibility and the base film and the GO selection layer have good bonding force; then, a solution of the host-guest complex formed by encapsulation is mixed with a GO dispersion solution to obtain a coating liquid, and the coating liquid is uniformly deposited on the base film by using a pressure-assisted filtration method to obtain a GO nanofiltration membrane. Through interlayer cross-linking, the formation of a more ordered channel is promoted, and the membrane is endowed with good stability and screening performance.