1315 results about "Supermolecule" patented technology

The invention relates to the technical fields of medicines, foods, daily chemicals and the like, in particular to two supramolecular eutectic crystals for better solving the application problem of EGCG (epigallocatechin gallate). The preparation method comprises the following steps: firstly, enabling EGCG and betaine to form a supramolecular EGCG betaine eutectic through a supramolecular technology, and synthesizing the supramolecular EGCG betaine eutectic through a supramolecular modification reaction by taking EGCG and betaine as precursors, so that the stability of EGCG can be improved to a certain extent, and meanwhile, the EGCG and the betaine are combined to play a synergistic effect; the supramolecular raw material is formed by enabling supramolecular EGCG betaine eutectic crystals and cyclodextrin to form a supramolecular raw material through host-guest self-assembly, and hydroxypropyl-beta-cyclodextrin and supramolecular EGCG betaine are subjected to host-guest self-assembly to obtain the supramolecular raw material, the supramolecular raw material prepared by the method can solve the stability problem of EGCG, the bioavailability of EGCG is improved, and the bioavailability of EGCG is improved. And meanwhile, the composition has good effects of resisting oxidation, whitening, resisting inflammation, controlling oil and the like, and has a good application prospect.

The invention discloses a novel PDRN, a supramolecular liposome containing the PDRN as well as a preparation method and application of the supramolecular liposome. The preparation method of the novel PDRN comprises the following steps: (1) mixing a tissue raw material and PBS, crushing, carrying out enzymolysis, adding SDS, a Tween20 solution, polyethylene glycol octylphenol ether, a TE buffer solution and NaCl, stirring, centrifuging, mixing a supernatant with absolute ethyl alcohol, and standing to obtain a DNA crude extract; (2) carrying out breaking shearing treatment by using an ultrasonic breaking instrument; and (3) carrying out enzymolysis treatment by using restriction endonuclease and deoxyribonuclease, and the like. The PDRN supramolecular liposome is obtained by wrapping the PDRN with fatty acid extracted from marine microalgae. The fish testis are used as the raw material source, the selection range of the raw materials is widened, the preparation cost is reduced, and the organic reagent used in the preparation method is ethyl alcohol which is easy to remove and harmless.

The invention relates to the technical field of fluorescence sensing, in particular to a preparation method and application of an Nd (III)-based hydrogen bond organic framework crystalline material. According to the Nd (III)-based hydrogen bond organic framework crystalline state material, Nd (III) serves as a central metal ion and is coordinated with 9 oxygen atoms, and adjacent Nd (III) are connected through H2 (4-CPCA) ligands to form a one-dimensional chain structure. One-dimensional chains are bridged through H2 (4-CPCA) ligands to form a two-dimensional double-layer planar structure, and two-dimensional surfaces are further stacked through the interaction of a large number of intermolecular hydrogen bonds to form a three-dimensional supramolecular structure. The Nd (III)-based hydrogen bond organic framework crystalline material has good fluorescent property and stability, and can be applied to the field of fluorescence sensing.

The invention discloses a supramolecular ellagic acid ionic salt composition, a preparation method thereof and application of the supramolecular ellagic acid ionic salt composition in preparing cosmetics. The supramolecular ellagic acid ionic salt composition is prepared from raw materials including ellagic acid, and the concentration of the ellagic acid accounting for the total volume of the supramolecular ellagic acid ionic salt composition is 0.1% w / v-2% w / v; the concentration of PEG accounting for the total volume of the supramolecular ellagic acid ionic salt composition is 15% w / v-85% w / v, and the average molecular weight of PEG is 200-400; the concentration of the antioxidant accounting for the total volume of the supramolecular ellagic acid ionic salt composition is 0.1% w / v-0. 5% w / v; and the molar weight of the basic ion ligand is 1-6 times that of the ellagic acid. According to the supramolecular ellagic acid ionic salt composition and the preparation method thereof disclosed by the embodiment of the invention, the solubility, permeability and formula stability of ellagic acid can be improved on the basis that the ellagic acid has oxidation resistance.

The invention provides a hydroxytyrosol supramolecular compound and a preparation method and application thereof, and belongs to the technical field of cosmetics and biological medicine, the supramolecular compound comprises the following chemical components by mass: 0.01-10% of hydroxytyrosol, 2-45% of an amino acid compound, 2-20% of alpha hydroxy acid, 2-30% of urea, and 15-92% of water. The supramolecular compound can promote transdermal delivery of hydroxytyrosol and maintain the biological activity of hydroxytyrosol, shows high biocompatibility, and can be applied to product development in the antibacterial field, the regeneration field and the anti-aging field.

The invention discloses an inorganic-organic hybrid compound crystal and a preparation method thereof, and belongs to the technical field of organic-inorganic hybrid materials. The preparation method comprises the following steps: mixing raw materials containing hydroiodic acid, organic cage molecules RCC3 and a lead source with a solvent, and carrying out solvothermal reaction to obtain the inorganic-organic hybrid compound crystal. The chemical formula of the prepared inorganic-organic hybrid compound crystal is ({H18 [C72H108N12] 2 [(Pb10I36)]}. 2I), wherein [C72H108N12] is RCC3 acidified by hydroiodic acid, the crystal has a supramolecular three-dimensional structure assembled by a [Pb5I8] 3-anion cluster unit and a protonated RCC3 molecular cage through electrostatic and hydrogen-bond interaction, and belongs to a monoclinic system, and the space group is P21. The crystal structure is a metal halide-based organic-inorganic hybrid crystal constructed by taking an organic molecular cage as nitrogen-containing cations and lead iodide for the first time.

The present invention relates to the field of oilfield chemical technology, and proposes a fast-soluble hydrophobic associating polymer for reinjection water for fracturing and a preparation method thereof. Hydrophobic functional monomers and non-ionic polarity regulators are prepared into polymerizable hydrophobic associating micelles, and the polymerizable hydrophobic associating micelle solution and conventional monomer aqueous solution are mixed. The molecular weight of the copolymer is regulated by a molecular weight regulator, and the fast-soluble hydrophobic associating polymer for reinjection water is obtained after reaction, granulation, drying and crushing. It comprehensively utilizes the synergistic effect of the multi-component supramolecular forces of the ternary hydrophobic functional monomers to achieve stability regulation of the associating micelles, and obtains a three-dimensional network structure of salt-resistant polymers with a dense associating network and a strong associating effect; introduces a polarity regulator containing a non-ionic hydrophilic structure, and utilizes self-assembly to form a hydration layer on the surface of the associating micelles, thereby weakening the water-phase aggregation effect and ion shielding effect of the hydrophobic structure, which is beneficial to the stretching of the molecular chain in the water phase, and obtaining the online mixing and fast-dissolving efficiency of the reinjection water, and having both high salt resistance and strong sand carrying performance.

The invention provides an enzyme response type supramolecular PDRN-mini ECM liposome and a preparation method and application thereof.The enzyme response type supramolecular PDRN-mini ECM liposome comprises phospholipid, a membrane stabilizer, a supramolecular compound and an emulsifier, a water phase formed by the supramolecular compound and the emulsifier serves as an inner core, and the supramolecular compound is formed by PDRN and mini ECM through intermolecular acting force; the mini ECM is formed by self-assembly of collagen peptide, elastin and hyaluronic acid. The supramolecular PDRN-mini ECM liposome with uniform particle size and good stability is obtained through a microfluidic technology, the process is simple, the controllability is high, and amplification is easy.

The invention discloses a preparation method and application of a recombinant XVII type collagen and adenosine eutectic substance. According to the invention, adenosine and recombinant XVII type collagen are combined through a non-covalent bond to form a novel supramolecular eutectic substance. The solubility and skin permeability of the eutectic substance are improved through the synergistic effect of the two substances, and the performance of fixing hair and promoting hair papilla cell proliferation is also enhanced.

The invention provides a mechano-electric coupling hydrogel microsphere with stable mechanical property and low loss transduction as well as a preparation method and application thereof, and belongs to the technical field of tissue engineering bioremediation materials. According to the invention, supramolecular engineering and microfluidic technologies are utilized, and a slip ring structure polyrotaxane and conductive polypyrrole network is introduced to construct stress-electric coupling hydrogel microspheres. The molecular slippage mechanism of the slip ring structure stores and releases mechanical energy to reduce mechanical loss, and the conjugated pi-electron movement in the conductive network improves the electron transfer efficiency in the microsphere, so that the loss in stress-electricity conversion is reduced for the first time. Compared with the traditional piezoelectric hydrogel microspheres, the stress-electric coupling efficiency of the low-dissipation microspheres is improved by 2.3 times, and the energy dissipation rate is reduced to 43%. The mechano-electric coupling hydrogel microspheres can reduce cartilage injury of rats, improve behavior results and promote treatment of osteoarthritis by recovering low-loss transduction between tissues.

The present invention provide novel immunofiber compositions for protein or peptide purification and simple and cost-efficient methods and systems using these compositions. In some embodiments, the immunofibers comprise a customized Z-33 peptide derived from Staphylococcus aureus Protein A which is used to construct immuno-amphiphile molecules that assemble into immunofibers in aqueous solution with bioactive epitopes on the surface and have peptide or protein binding ability.

The invention discloses a preparation method of high-flexibility and high-adhesiveness rosin gel, which comprises the following steps of: performing ring-opening reaction on epoxy chloropropane by using rosin as a nucleophilic reagent, and promoting cross-linking by using urushiol as a cross-linking agent, so that the rosin, the epoxy chloropropane and the urushiol form a firm gel network through hydrogen bonds and covalent bonds; the existence of rosin and urushiol in the gel system endows the gel system with excellent adhesion performance, and the formation of a supramolecular network endows the gel system with excellent flexibility. The method disclosed by the invention is simple in steps, and the prepared rosin gel system is high in stability, good in flexibility and strong in adhesive capacity and has a good application prospect.

The present invention relates to the technical field of oilfield chemistry, and provides a wormlike supramolecular associated micelle, a hydrophobic associated copolymer and a preparation method thereof, the wormlike supramolecular associated micelle comprises a soft template, a hydrophobic functional monomer 1, a hydrophobic functional monomer 2 and a polarity regulator, the soft template is a long-chain molecular polymer and has an active functional group, and the polarity regulator is a hydrophobic functional monomer 2. The hydrophobic functional monomer 1 is an anionic-nonionic surfactant with polymerizable double bonds, the hydrophobic functional monomer 2 is a cationic-nonionic surfactant with polymerizable double bonds, and the polarity regulator is a micromolecular organic compound. The problems of poor resistance reduction, sand carrying capacity and the like of the fracturing fluid in the construction process due to dissociation of a polymer molecular network structure and sudden reduction of rheological property and viscoelasticity are solved.

The invention relates to the technical field of cosmetic functional raw material preparation methods, in particular to a plant extract and an extraction method and application thereof. The invention provides a plant extraction method, which comprises the following steps: adding a glycol ether or polyhydric alcohol solvent containing 5-7 carbon atoms into a product containing phenolic acid compound components and lignan compound components, carrying out homogeneous reaction, carrying out heating extraction, and collecting the extract. By adopting a supramolecular technology, phenolic acid compound components can form a supramolecular solvent with glycol ether or polyol solvents containing 5-7 carbon atoms, and the supramolecular solvent is further combined with lignan compound components to form a supramolecular structure, so that the stability of an extracting solution is remarkably enhanced, the specific enrichment of the lignan compound components is realized, and the specific enrichment of the lignan compound components is realized. The problems that an existing extraction technology is poor in stability, poor in formula applicability, not prominent in effect and the like are successfully solved.

The invention relates to the technical field of oilfield chemistry, and provides a reinjection water instant hydrophobic association polymer for fracturing and a preparation method thereof. The preparation method comprises the following steps: preparing a polymerizable hydrophobic association micelle from a hydrophobic functional monomer and a nonionic polarity regulator, mixing the polymerizable hydrophobic association micelle solution with a conventional monomer aqueous solution, regulating the molecular weight of the copolymer by a molecular weight regulator, reacting, granulating, drying and crushing to obtain the reinjection water instant hydrophobic association polymer. By comprehensively utilizing the synergistic effect of multi-element supramolecular force of a ternary hydrophobic functional monomer, the stability of associated micelles is regulated and controlled, and a salt-resistant polymer three-dimensional network structure with a dense association network and a strong association effect is obtained; a polarity regulator containing a nonionic hydrophilic structure is introduced, a hydration layer is formed on the surface of associated micelles by utilizing a self-assembly effect, a water phase aggregation effect and an ion shielding effect of a hydrophobic structure are weakened, stretching of a molecular chain in a water phase is facilitated, online mixing instant efficiency of reinjection water is obtained, and high salt resistance and strong sand-carrying performance are achieved.

The invention designs and synthesizes a tetraphenyl ethylene covalent molecular cage with pyridine functionalization, and an AIE supermolecule photosensitizer is obtained through coordination and the synergistic effect of a subject and an object. The TPE unit enhances the photophysical properties of the photosensitizer and endows the photosensitizer with the AIE characteristic; the molecular cage and tetraphenylporphyrin are combined through a host and a guest, so that self-aggregation of porphyrin in water is further inhibited, ROS generation is promoted, and cancer cells are effectively killed through photocatalysis NADH oxidation assistance.

The invention discloses synthesis of a cup crown compound adsorption material and a method for deeply and selectively extracting indium from an acid complex system, and belongs to the technical field of non-ferrous metallurgy. According to the synthesis of the cup-crown compound adsorption material and the method for deeply and selectively extracting indium from the acid complex system, based on the pre-organizability and complementary molecular design principle of subject-object chemistry, a 15-crown-5 ether subunit is introduced into a calix [4] arene structure to form a cup-crown supramolecular compound; and furthermore, the material is loaded on the surface of SiO2 particles to form a stable adsorption material, so that deep selective separation and extraction of indium in an acidic complex system can be realized.

The invention relates to the technical field of semiconductor devices, in particular to a monomolecular device based on supramolecular induced electrochemical polymerization and a preparation method thereof.The molecular device comprises a graphene point electrode pair and a monomolecular chain, and the monomolecular chain is connected between the graphene point electrode pair; wherein the single molecular chain is formed through supramolecular induced electrochemical polymerization; the host molecule encompasses the guest molecule in the cylindrical cavity of the host molecule to form a supramolecule; the host molecule is selected from cyclodextrin, and the guest molecule is selected from thiophene or thiophene derivatives; the tail ends of the graphene point electrode pairs are modified by amino-containing monomer molecules respectively, the monomer molecules are connected with the graphene point electrode pairs through amido bonds, and the monomer molecules serve as a starting unit and a terminating unit of supramolecular induced electrochemical polymerization, so that assembly of functional cores of a monomolecular device is facilitated; according to the technical scheme provided by the invention, the problem of how to prepare an efficient and reliable monomolecular device by utilizing an electrochemical polymerization method is solved.

The application provides a preparation method of a self-coiled structure molybdenum disulfide / nitrogen-doped porous carbon composite material, a product and application, high-content nitrogen-doped porous carbon material is synthesized by inducing dicyandiamide molecules to undergo a supramolecular self-assembly process, and on this basis, a hydrothermal reaction is carried out to coat molybdenum sulfide sheet layer material on the surface, and finally, a self-heating coiling treatment is carried out to form a carbon-based electrocatalyst of the self-coiled structure molybdenum disulfide / nitrogen-doped porous carbon. Compared with a high specific surface area carbon-based catalyst, high doping concentration of nitrogen atoms can provide more electron-rich properties to facilitate the adsorption of substances, and the self-coiled carbon-based material can exhibit very excellent electrochemical performance, especially in the aspect of electrochemical hydrogen production. The preparation method is simple in operation, low in preparation cost and suitable for large-scale production.

The invention belongs to the field of chemical materials, particularly relates to pyrenyl beta-cyclodextrin magnetic graphene oxide gel, a preparation method of the pyrenyl beta-cyclodextrin magnetic graphene oxide gel and application of the pyrenyl beta-cyclodextrin magnetic graphene oxide gel in food safety detection, and discloses the pyrenyl beta-cyclodextrin magnetic graphene oxide gel. The gel is obtained by covalent bond connection and supramolecular interaction-host-guest assembly of magnetic graphene oxide, beta-cyclodextrin molecules and pyrene derivatives. The gel belongs to a lamellar stacked three-dimensional structure, and compared with traditional gel, the gel has the advantages that the overall pore diameter is increased, the separation flux is improved, the separation efficiency is improved, adsorption equilibrium can be quickly achieved within 0.5 min, and specific separation and adsorption of mycotoxin in a complex food sample are facilitated.

The invention discloses a simple preparation method of a barium-based metal organic framework (Ba-H2Sip) and proton conduction application of the barium-based metal organic framework (Ba-H2Sip), belongs to the field of functional material synthesis and energy application, and is characterized in that functional differentiation design of a 5-sulfoisophthalic acid ligand: a sulfonic group forms a two-dimensional layered structure by chelating Ba < 2 + >; the carboxyl groups are differentiated into'anchoring carboxyl groups' for constructing a three-dimensional supramolecular skeleton and'proton supply carboxyl groups' for providing a proton source, and the design is reported for the first time in Ba-based MOFs; according to the present invention, the large-scale preparation can be achieved by stirring the low-cost raw material in 1 mol / L hydrochloric acid at the room temperature, the yield exceeds 70%, the product can resist 8 M acid and pH = 13 alkali liquid, the conductivity at 90 DEG C / 90% humidity can achieve 1.39 * 10 <-2 > Scm <-1 >, the high-temperature process is not required, the raw material is low in cost and easy to obtain, and the feasible scheme is provided for the high-efficiency proton conductor industrialization.

The invention relates to the technical field of composite materials, in particular to a high-strength elastic composite aerogel and a preparation method thereof.Negative Poisson ratio composite aerogel designed with a centripetal structure cooperating with a supramolecular system is prepared, the supramolecular system design is adopted, a hydrogen bond network of nanofibers serves as a weak interface bonding layer, and the elastic composite aerogel with the high strength is prepared. The fiber and the silane-based material interface are covalently interlocked to form a firm supramolecular system, and a centripetal structure is cooperated to realize a coupling effect between resistance and deformation. Through the cooperative strategy, the composite aerogel obtains excellent specific modulus and good recovery speed, and can be qualified for high-impact and high-strength application scenarios.

The invention relates to the technical field of cosmetics, in particular to a preparation method and application of a supramolecular solvent containing puerarin. The supramolecular solvent containing puerarin comprises puerarin, a hydrogen bond donor and a hydrogen bond receptor, the molar ratio of the hydrogen bond donor to the acceptor is (1-3): (1-2). The puerarin-containing supramolecular solvent formed by using weak interaction force such as hydrogen bonds can effectively solve the problems that puerarin is easy to separate out in the product and poor in transdermal absorption and the like, and meanwhile, the puerarin-containing supramolecular solvent can synergistically promote the effect of puerarin in the oil-control acne-removal product. Cosmetics prepared by adopting the supramolecular solvent prepared by the invention have good oil control and soothing effects, and the preparation process is simple, large-scale production is easy, and the properties are stable.

The present invention relates to a preparation method and application of a supramolecular aggregate surfactant, and belongs to the field of supramolecular coordination chemistry, surface modification engineering and hydrophobic coating technology. In the present invention, 4-hydroxypyridine-2,6-dicarboxylic acid and malonic acid prepare an adhesive ligand, and with the help of the coordination of the carboxyl structure and lanthanum ions on 4-hydroxypyridine-2,6-dicarboxylic acid and perfluorooctanoic acid, a supramolecular aggregate in a nano-aggregated state is obtained, which is self-assembled into a supramolecular aggregate surfactant. The active agent can solubilize fluoride and can also be applied in the field of hydrophobic coatings. The coating has the characteristics of imitating lotus leaf structure and hydrophobic wax, and has good hydrophobic properties.

The invention discloses a tripterine-sophocarpidine self-assembled nanoparticle and application thereof in preparation of an anti-tumor drug, and belongs to the field of biological medicine. The nanoparticles are formed by self-assembly of the tripterine and the sophocarpidine through supramolecular interaction, the molar ratio of the tripterine to the sophocarpidine is 1: 1-1: 3, and the self-assembly system effectively solves the problems of low Cst solubility, poor bioavailability, rapid in-vivo removal and the like; the inhibition effect on triple negative breast cancer (TNBC) is remarkably enhanced through the synergistic effect of Cst and Mar, and a new strategy is provided for expanding the application of a traditional Chinese medicine carrier-free self-assembly nano drug delivery system in the anti-tumor field.

The invention discloses polysaccharide fluid hydrogel for digestive tract submucous injection and a preparation method of the polysaccharide fluid hydrogel, and belongs to the field of medical biological materials. According to the invention, carboxylated chitin or a carboxylated chitosan derivative with a mass percentage of 0.1-6%, or hydroxyalkylated chitin or a hydroxyalkylated chitosan derivative and collagen or gelatin are subjected to micro-crosslinking to form a low-crosslinking-degree supramolecular derivative as a solute; the polysaccharide fluid hydrogel is formed by taking water, normal saline, a physiological equilibrium solution, a phosphate buffer solution or a Green's solution as a solvent. By controlling the molar ratio of the raw materials to the cross-linking agent and performing micro-crosslinking with a small amount of the cross-linking agent, the prepared low-crosslinking-degree supramolecular derivative can form hydrogel in an aqueous solvent, has shear thinning and self-repairing characteristics, has certain viscosity, is easy to push and inject, and can be applied to the field of water treatment. The lifting height of the mucous membrane can be effectively kept, the height keeping time can be effectively prolonged, the mucous membrane is not prone to overflowing under the condition that the mucous membrane is damaged, an endoscope injection device is not blocked, and the material is an ideal material for forming a safe liquid pad through digestive tract submucous injection.

The invention discloses a self-classification driven supramolecular dimer as well as a preparation method and application thereof. According to the supermolecule composite material, cucurbit [8] uril serves as a subject, a phenylpyridinium derivative G serves as an object, and a small-size supermolecule dimer with red / near-infrared delayed emission is formed through subject-object inclusion interaction and a self-classification strategy. The supramolecular dimer structure inhibits distorted intramolecular charge transfer (TICT) and promotes space charge transfer (TSCT), enabling red thermally activated delayed fluorescence (in some embodiments, 620 nm) and near infrared phosphorescence (in some embodiments, 740 nm) of simple organic small molecules. The proposed synergistic supramolecular strategy provides a new way for realizing simple red / near-infrared delayed emission of small organic molecules in a water phase, and has potential application value in the fields of biological materials and the like.

The invention relates to the technical field of nuclear waste treatment, in particular to a cucurbituril-based supramolecular organic framework material as well as a preparation method and application thereof. A construction unit of the supramolecular organic framework material is constructed by taking cucurbit [8] uril (CB8) as a subject and terephthalyl viologen ligand 1, 1 ''-(1, 4-phenylene) bis ([4, 4 '-bipyridyl]-1-onium) salt (PBV. 2X) as an object through the bonding effect of the subject and the object; in the molecular structure of the supramolecular organic framework material, the construction units are staggered and stacked in parallel in the space, and NO3 <-> is located at the gap of the adjacent CB8. The supramolecular organic framework material disclosed by the invention has high structural stability and cationic framework characteristics, and a rigid framework and a pyridine conjugated system of CB8 endow the material with excellent chemical / irradiation stability, so that the material shows ultrahigh removal rate on ReO4 <-> / TcO4 <-> in extreme environments (strong acid, strong alkali and high irradiation).

The invention relates to the technical field of agricultural fertilizers, and discloses an environment-friendly organic slow-release fertilizer and a preparation method thereof, the environment-friendly organic slow-release fertilizer comprises the following raw materials by mass: 55-65% of a decomposed straw carrier; 20%-30% of a slow release carrier; 8%-12% of a microencapsulated bacterial agent; 3%-5% of a cross-linking agent; and 2%-4% of an auxiliary additive. The porosity of the decomposed straw carrier is larger than or equal to 65%, the carbon nitrogen ratio is (25-28): 1, the particle size is 0.5-1.5 mm, and the water holding capacity is larger than or equal to 2.5 g / g. The environment-responsive supramolecular slow-release system is constructed, supramolecular host-guest interaction and temperature-responsive polymer synergism are utilized, the fertilizer release rate can be dynamically regulated and controlled along with the crop rhizosphere temperature, nitrogen can be accurately released in the crop fertilizer demand peak period, the matching degree of a nitrogen release curve and crop demand is increased to 90% or above, and the nitrogen release rate is increased to 90% or above. Compared with the traditional organic fertilizer with the problems of uncontrolled nutrient release, excessive nutrient loss in the early stage and insufficient supply in the later stage, the fertilizer realizes the high conformity of nutrient release and crop requirements.