2results about How to "Regulated release" patented technology

This invention discloses an anti-inflammatory peptide derived from pearl oysters and its applications, relating to the field of bioactive peptide technology. The amino acid sequence of this anti-inflammatory peptide is TAMY. The anti-inflammatory peptide derived from pearl oysters provided by this invention can regulate the release of cellular inflammatory mediators, reduce the levels of NO and pro-inflammatory cytokines (such as TNF-α, IL-6, and IL-1β), and simultaneously promote the secretion of anti-inflammatory cytokines (such as IL-10), exhibiting excellent anti-inflammatory activity and suitable for use in functional foods, cosmetics, or pharmaceutical ingredients.

The invention discloses a drug-loading bionic scaffold based on in-situ emulsified and homogenized PLGA microspheres, a preparation method and application, and the preparation method comprises the following steps: step 1, adding hydroxyapatite into a collagen solution, fully mixing, adding a photoinitiator, and fully reacting to obtain a mixed solution A; 2, dissolving a polylactic acid-polyglycolic acid copolymer PLGA, adding a drug solution needing to be loaded, and fully mixing to obtain a mixed solution B; and 3, adding the mixed solution B serving as an oil phase into the water-phase mixed solution A obtained in the step 1, carrying out oscillation emulsification, and carrying out photocuring to obtain the drug-loaded bionic scaffold containing the homogenized PLGA microspheres, according to the homogenized PLGA microsphere functionalized drug-loading bionic stent, PLGA microspheres with uniform size are obtained, the encapsulation efficiency of drugs is improved, and the release process of the drugs can be regulated and controlled.