72 results about "Chitosan coating" patented technology

The invention discloses multi-layer response type ecological seed paper and a preparation method thereof. According to the invention, the microencapsulated seed adopts a sodium alginate and chitosan double-layer coating process, and the pH response characteristic is combined, so that the problem of seed damage caused by high temperature or mechanical pressure in the traditional seed paper processing process is effectively solved. The sodium alginate gel layer forms a physical barrier through ionic crosslinking, so that direct impact of a processing environment on the seeds is isolated; the pH sensitivity of the chitosan coating ensures that the seeds are only released under the soil neutral condition, and poison of acidic or alkaline environment to seedlings is avoided. When the soil moisture content exceeds a threshold value, the hydrogel grid structure is rapidly expanded and disintegrated, and the slow-release fertilizer and the nitrogen-fixing flora are synchronously released. According to the dual intelligent response system, the survival rate of the seeds is increased, accurate space-time matching of nutrient release and seed germination is achieved, and in a mine remediation scene, heavy metal adsorption and soil microbial community reconstruction can be completed at the same time by adjusting the aperture of the hydrogel and the variety of probiotics.

The invention discloses a growth regulator for promoting colonization of plant rhizosphere microorganisms and application of the growth regulator to crops, a preparation method of the growth regulator comprises the following steps: S1, dropwise adding an aqueous solution of modified chitosan and a compound bacteria solution into a saturated boric acid solution of 1-2% calcium chloride, crosslinking and curing for 3-4 hours, washing with sterile water for 3-5 times, and drying to obtain the growth regulator for promoting colonization of the plant rhizosphere microorganisms; immobilized microorganisms are obtained; s2, sequentially adding nanocellulose crystals, sodium polyaspartate and organic fertilizer into the enteromorpha extracting solution, uniformly stirring and mixing, adding immobilized microorganisms, uniformly mixing, granulating, coating with modified chitosan, and drying to obtain the growth regulator. Through step-by-step design of microorganism immobilization, nutrition compounding and chitosan coating, function integration of microorganism protection, nutrition release and environmental response is achieved, the colonization efficiency of rhizosphere microorganisms is remarkably improved, the soil microenvironment is improved, and finally comprehensive improvement of plant growth and stress resistance is achieved; and the method has relatively high social use value and application prospect.

The invention belongs to the technical field of wall joint filling, and relates to a wall cracking joint filling agent and a wall joint filling process, the wall cracking joint filling agent comprises a cement-based cementing material, fine aggregate, modified toughening fiber, modified nano zinc oxide, a dispersing agent, a defoaming agent, a water-retaining agent and a mildew preventive; the modified toughened fiber is obtained by sequentially carrying out alkali etching, dopamine coating and intercalated kaolin loading on polyacrylonitrile fiber; the modified nano-zinc oxide is obtained by modifying nano-zinc oxide through a silane coupling agent and coating and modifying the nano-zinc oxide through chitosan. According to the wall crack repairing agent provided by the invention, the modified toughening fibers and the modified nano zinc oxide which are subjected to surface functionalization treatment are introduced, so that the crack resistance and toughness of a cement-based crack repairing material can be remarkably improved, the occurrence probability of secondary cracking after repairing can be remarkably reduced, meanwhile, lasting and effective mildew-proof and antibacterial capabilities can be provided, microbial erosion can be inhibited, and the service life of the wall crack repairing agent is prolonged. And good construction operability and basic mechanical properties of the material are maintained.

The invention discloses an anti-seepage, water-locking and fertilizer-retaining sandy land soil conditioner, and relates to the technical field of sandy land soil improvement, the anti-seepage, water-locking and fertilizer-retaining sandy land soil conditioner comprises the following raw materials by mass: 50-60% of decomposed cow dung; 15 to 20% of modified straw fiber; 12 to 15% of a sodium carboxymethyl cellulose solution with a concentration of 0.1%; 3 to 5% of bentonite; 1-2% of a microbial agent; 0-15% of a slow-release compound fertilizer; 0.5-1% of polyglutamic acid; and 0.5-1% of a stone-chitosan coating agent. The invention also discloses a preparation method of the anti-seepage, water-locking and fertilizer-retaining sand soil conditioner. The preparation method comprises the following steps: step 1, straw modification; step 2, cow dung decomposition; step 3, preparing a colloidal solution; step 4, mixing and granulating; step 5, coating treatment; and step 6, post-processing. By adopting agricultural wastes as main raw materials, resource utilization of the wastes is realized, and a biodegradable material is introduced to replace synthetic resin, so that the degradation period is shortened to 18-24 months.

The invention discloses a preparation method of a modified chitosan coating liquid for fruit preservation, which comprises the following steps: grafting gallic acid to chitosan by using a biological coupling method to obtain gallic acid modified chitosan; and dissolving anhydrous calcium chloride powder in the gallic acid modified chitosan to obtain the chitosan-gallic acid / Ca < 2 + > coating liquid material. The invention also discloses an application of the preservative in fruit preservation. The modified chitosan coating liquid prepared by the invention forms a high-density spatial network structure through a biological coupling method and a metal coordination reaction, and has good antibacterial and antioxidant activity, mechanical properties, water vapor barrier property and peel adhesion. The prepared modified chitosan coating liquid can form a uniform film on the surface of the fruit, weaken respiration, prevent and inhibit postharvest diseases, reduce the weight loss rate and rotting rate, maintain the brightness of the fruit and prolong the shelf life of the fruit.

The invention relates to the technical field of self-leveling, and particularly discloses high-density gypsum-based self-leveling mortar and a preparation method thereof, the high-density gypsum-based self-leveling mortar comprises building gypsum, modified heavy calcium powder, quartz sand, modified silica powder, Portland cement and a plurality of additives, the modified heavy calcium powder is activated by a silane coupling agent and is subjected to composite coating modification by sodium alginate-microcrystalline cellulose, the modified silica powder is activated by a silane coupling agent and is subjected to coating modification by chitosan, and the preparation method comprises the following steps: S1, preparing the chitosan-coated modified silica powder; s2, preparing sodium alginate-microcrystalline cellulose composite coated modified heavy calcium powder; s3, uniformly mixing all the dry materials, adding the mixed admixture and water, and stirring to prepare mortar; according to the self-leveling mortar disclosed by the invention, pores are filled in a self-adaptive manner through the characteristic that the surface coating layers of the modified heavy calcium powder and the modified silica powder absorb water and swell, a stable high-molecular reinforced framework is formed after drying, and the high-molecular reinforced framework and mortar components generate a synergistic effect, so that the compactness of the self-leveling mortar is effectively improved.

The invention discloses a chitosan grafted tannic acid-iron composite coating solution based on mussel adhesion simulation and application of the chitosan grafted tannic acid-iron composite coating solution in mango preservation, and belongs to the technical field of food preservation. According to the method, tannic acid is grafted to chitosan through a free radical mediation method to form a compound, then ferric ions are added for crosslinking, and a composite coating film with mussel adhesion imitating characteristics is constructed. According to the method, the technical problems that a traditional chitosan coating film is poor in adhesion, low in polyphenol utilization rate and prone to failure in a high-humidity environment are solved, the shelf life of mangoes can be effectively prolonged, the postharvest loss is reduced, and the method has important industrial application value.

The invention belongs to the field of functional feeds, and discloses a preparation method of a coarse cereal feed for sheep, which comprises the following steps: crushing one or two coarse cereals of buckwheat, broom corn millet, millet and sorghum, and mixing the crushed coarse cereals with raw materials such as enzymolysis soybean meal and alfalfa meal; adding a compound bacteria solution containing lactobacillus plantarum, lactobacillus acidophilus and saccharomyces boulardii for anaerobic fermentation; the nano zinc oxide and the yucca extract are further strengthened to improve the oxidation resistance and ammonia reduction capacity of the feed; and finally, granulating and spraying a sodium alginate-chitosan coating. Through coarse cereal combination optimization, soybean meal enzymolysis pretreatment and composite flora fermentation synergistic effect, the feed protein utilization rate, the fiber degradation rate and the animal production performance are remarkably improved. Experiments show that the milk fat content of the saanen milk goats fed with the feed is increased by 15-23%, the daily gain of the Alba cashmere goats is increased by 25-35%, the feed conversion ratio is optimized to 11.2-12.3: 1, and compared with the prior art, the feed has outstanding nutrition balance and application pertinence.

The invention discloses a vanillin deep eutectic reagent / chitosan coating preservative as well as a preparation method and application thereof, and belongs to the technical field of food preservatives. The vanillin deep eutectic reagent / chitosan composite coating preservative is prepared from the following raw materials in parts by mass: 1 to 9 parts of vanillin deep eutectic reagent and 10 parts of chitosan. Or 2-6 parts by mass of a film-forming agent. The vanillin deep eutectic reagent / chitosan membrane liquid or the vanillin deep eutectic reagent / chitosan membrane prepared by the invention has the technical effects of resisting microorganisms and oxidation. The liquid film can play a fresh-keeping effect on the fresh fruits through an anti-oxidation and anti-microbial mechanism so as to prolong the shelf life. And the shelf life of the food is prolonged in a film-covering and vacuumizing mode on the fresh fruits. The raw materials are natural, safe, environment-friendly, low in price and easy to obtain, the preparation process is simple and convenient, and the potential value of large-scale production and market application is achieved.

The invention relates to the technical field of soil improvement, and discloses a preparation method and application of a saline-alkali soil improvement fertilizer. The saline-alkali soil improvement fertilizer sequentially comprises acorus calamus-gypsum particles, a humic acid loaded activated carbon coating layer and a chitosan coating layer from inside to outside. The saline-alkali soil improvement fertilizer provided by the invention can effectively reduce the salt content and pH value of saline-alkali soil, and can effectively improve the organic matter content and total nitrogen content of the saline-alkali soil. The saline-alkali soil improvement fertilizer provided by the invention can effectively inhibit salt and alkali return of saline-alkali soil.

The invention provides a preparation process of a hyaluronic acid-chitosan coating and a contact lens with the hyaluronic acid-chitosan coating, and belongs to the technical field of surface coatings of contact lenses. The preparation method comprises the following steps: carrying out surface grafting treatment on a bare contact lens with high oxygen permeation rate, and alternately coating a chitosan solution and a hyaluronic acid solution with certain concentrations, so as to form a composite coating consisting of discontinuous single layers on the surface of the contact lens; the obtained contact lens with the hyaluronic acid-chitosan coating has high oxygen permeation rate, good antibacterial effect and moisturizing capacity, and has important significance.

This invention is related to the fields of medical biotechnology, nanobiotechnology, and nanomedicine. It involves a nanomedicine product that can release HOC1 (hypochlorous acid) at the tumor site in a controlled manner to treat lung cancer. HOC1 is a potent antimicrobial and antitumor agent that can target tumor tissues while minimizing damage to healthy tissues. The produced nanoparticles have a two-layer structure: the inner layer contains alginate, PFP (perfluoropentane), and Ca(OCl)2 to release HOC1, and the outer layer has a chitosan coating with folate and salicylic acid for targeting and proton release. The production process involves nanoemulsion and coating with the ionic gelation technique. When the nanoparticles are delivered to the lungs and targeted to cancer cells with folate, ultrasound radiation triggers the release of HOC1 to induce apoptosis and destroy cancer cells effectively, reducing side effects and improving treatment outcomes for lung cancer patients.

The invention discloses a chitosan modified turmeric-broccoli exosome hybrid nasal spray and application thereof, and belongs to the technical field of biological medicine and drug delivery. The nasal spray is formed by dispersing double plant exosome-lipidosome hybrids in a carrier for nasal cavities. The preparation method comprises the following steps: fusing curcumin carried by a turmeric exosome and sulforaphane carried by a broccoli bud exosome with a pH response liposome membrane containing 1, 2-dioleoyl-sn-glycerol-3-phosphoethanolamine, and modifying by chitosan to form a three-layer structure; the preparation method comprises the steps of exosome extraction, ultrasonic drug loading, liposome hybridization, chitosan coating and preparation blending. The nasal spray is high in entrapment efficiency and uniform in particle size, the chitosan enhances nasal adhesion, inflammation targeted drug release is achieved through pH response, the brain targeting efficiency and stability are excellent, and the adaptability to children is good. The curcumin and sulforaphane are used for targeted therapy of children autism spectrum disorder neuroinflammation, anti-inflammation and anti-oxidation are achieved through synergism of curcumin and sulforaphane, the curative effect is remarkable, and a new scheme is provided for treatment of related diseases.

The application provides a kind of image positioning sticker marking method based on iodine-gallium complex chelate, through chelation reaction to prepare excellent stability iodine-gallium complex developer, non-woven fabric substrate is modified by chitosan coating, combined with screen printing process to prepare high-precision positioning sticker, and establish standardized clinical marking process. The method uses iodine-gallium double element synergistic development mechanism, so that the CT value of the marking area is 350-400HU, the contrast of the surrounding tissue is improved by 40%, the development clarity retention rate is more than 92% after 48 hours of sticking, the positioning error is stable within 0.3mm, solves the pain points of traditional marking easy diffusion and poor adhesion. The application has excellent biocompatibility, the skin allergy rate is only 0.8%, the single patient positioning operation time is shortened to 5-10 minutes, the production cost is reduced by 40%, can be widely used in precise medical positioning scenes such as tumor radiotherapy and interventional surgery, has significant clinical popularization value.

The invention relates to a fresh-keeping method for Xuangxiang kiwi fruits by combining a lonicera confusa compound extract with chitosan coating treatment, and belongs to the technical field of fruit fresh-keeping. The method is characterized in that Xuangxiang kiwi fruits which are 80% mature, uniform in size, free of plant diseases and insect pests, free of mechanical damage and provided with fruit stems are soaked in a lonicera confusa compound extract for 8-12 min, and then chitosan treatment liquid is used for coating treatment. The lonicerae flos compound extract is prepared by the following steps: soaking a proper amount of high-quality lonicerae flos medicinal material, a proper amount of galangal medicinal material and a proper amount of clove medicinal material in water for 25 minutes, and boiling for 25 minutes Cooling and soaking the Xuangxiang kiwi fruits; and then carrying out film coating treatment by using a chitosan treatment solution. According to the method, the storage quality of the Xuangxiang kiwi fruits can be improved, the storage period of the Xuangxiang kiwi fruits can be prolonged, the fresh-keeping period of the Xuangxiang kiwi fruits at normal temperature can reach 50-60 days through treatment and is prolonged by 20-30 days compared with the fresh-keeping period of the Xuangxiang kiwi fruits without treatment, and the rotting rate can be reduced to 15% or below; the good sensory quality of the Xuangxiang kiwi fruits is maintained; the materials used for treatment are all natural plant raw materials, and are green, healthy and harmless.

This application relates to the field of water pollution control technology and discloses a method for preparing a sediment microecological reconstruction and pollutant-targeted immobilization conditioner. The method includes: modifying mesoporous silica with amino- and thiolated compounds and mixing it with biochar to obtain an adsorbent material; dispersing ferrous sulfate, sodium thiosulfate, and hydroxyapatite with the adsorbent material in a sodium alginate solution and adding it dropwise to a calcium chloride solution for cross-linking and chitosan coating to obtain microcapsules; compounding riboflavin, humic acid, carbon source nutrients, and adding signaling molecules to obtain a metabolic enhancer; compounding metalloenzyme inhibitors and activating them with microorganisms to obtain an activator; granulating and coating calcium carbonate, magnesium hydroxide, ferrous sulfate, sulfur powder, calcium peroxide, and sodium lactate to obtain buffer particles; mixing the adsorbent material, microcapsules, and buffer particles, spraying, adding the metabolic enhancer and activator, adding binders and pore-forming agents, granulating, drying, sieving, and spraying a protective film to obtain the conditioner. This application solves the technical problems of existing sediment conditioners, such as single function, uncontrolled release, and microecological imbalance.

The invention relates to the technical field of papermaking, and discloses a method for preparing cardboard paper by using composite mineral fibers, which comprises the following steps: dispersion and micro-nano treatment of attapulgite, preparation of a chitosan-attapulgite composite material, preparation of composite mineral fibers, paper pulp mixing and papermaking. Through micro-nanocrystallization treatment of attapulgite and coating modification of chitosan, the binding force of the composite mineral fiber and the paper pulp fiber is remarkably enhanced, and the mechanical properties such as tightness, burst index and ring crush index of finished paper are superior to those of standard requirements; besides, by adding the composite mineral fibers, fine fibers in the white water are removed, the fiber retention rate is increased, part of paper pulp fibers can be replaced, use of chemical auxiliary materials is reduced, the production cost is reduced, the production efficiency and the finished paper quality are improved, and the clean papermaking purposes of quality improvement, efficiency improvement and pollution reduction are achieved. Therefore, considerable economic benefits and social benefits are obtained.

The invention relates to the technical field of food, in particular to a preparation method of high-protein wheat germ nutritional compound granules. The method comprises the following steps: firstly, spraying chitosan on the surface of dry wheat germ powder, and then reducing the moisture content and inhibiting the enzyme activity through microwave treatment; the preparation method comprises the following steps: preparing wheat germ powder, then spraying sodium alginate to obtain stabilized wheat germ powder, finally, compounding the stabilized wheat germ powder with other nutritional ingredients, and carrying out high-pressure homogenization and spray drying to prepare the electuary. Through chitosan coating and microwave treatment, the nutrient retention rate and the storage stability of the wheat germs are remarkably improved, meanwhile, nutrient component loss and hidden danger of chemical additives in a traditional method are avoided, and an efficient and safe solution is provided for industrial application of the wheat germ nutrient compound granules.

The present application relates to the technical field of animal feed nutrition, and discloses a coated lavender essential oil microcapsule as well as a preparation method and application thereof.The microcapsule has a double-layer structure and comprises, from inside to outside, a core and a chitosan coating layer wrapped outside the core; the core is an essential oil-beta-cyclodextrin complex; the essential oil-beta-cyclodextrin complex is formed by vacuum adsorption inclusion of lavender ester essential oil obtained by short path distillation of lavender essential oil at 6-8 kPa and 45-55 DEG C and beta-cyclodextrin.The coated lavender essential oil microcapsule prepared by the double-layer coating technology realizes efficient utilization of lavender essential oil in livestock and poultry, significantly improves the growth performance of animals, effectively reduces the incidence of diarrhea, and shows the comprehensive effects of selective bacteriostasis and immune enhancement, thereby providing a feasible solution for green feed additives to replace antibiotics.

This invention discloses a microsphere-filled lysozyme-chitosan / casein composite antibacterial hydrogel and its preparation method. The technical solution involves using casein as a substrate, with lysozyme adsorbed onto the surface of casein micelles via electrostatic forces, and chitosan coating the outer layer of the lysozyme. The casein micelle solution, lysozyme solution, and chitosan solution are uniformly mixed through physical blending. Electrostatic forces physically cross-link the carboxyl groups on the casein micelle surface with the cations of lysozyme and chitosan amino groups, forming a microsphere-filled lysozyme-chitosan / casein composite hydrogel. This material exhibits excellent sustained-release performance, is environmentally friendly, has good biocompatibility, stable performance, and good antibacterial function.

The invention relates to the technical field of soil regeneration, and discloses a passivation method of arsenic-cadmium combined polluted soil, which comprises the following steps: S1, fully mixing any two or three of calcium bentonite, vermiculite and ferric sulfate in proportion, and carrying out ball milling activation treatment to form a mineral mixture; s2, adding pretreated manganese dioxide nanoparticles and ferric iron salt into the mineral mixture, adjusting the pH value of a reaction system to 4.0-5.5, and reacting for 8-12 hours under a stirring condition to form particles coated with a composite oxide layer on the surface; s3, drying and crushing the particles of which the surfaces are coated with the composite oxide layers, and carrying out sulfhydrylation chitosan coating, so as to obtain a passivation material; and S4, mixing the passivation material and the arsenic-cadmium combined polluted soil according to a ratio, and carrying out ball milling. The problem that the synchronous passivation effect of arsenic and cadmium in soil is poor can be solved.

The application discloses a regenerated cellulose non-woven fabric based on chitosan modification and a preparation method and application thereof, and comprises a non-woven fabric layer composed of regenerated cellulose fibers, wherein a gel layer formed by methacrylated chitosan and tannic acid is coated on any one side of the non-woven fabric layer, the content of the methacrylated chitosan in the gel layer is 10-30%, the content of the tannic acid is 1-30%, the grafting rate of the methacryl group in the methacrylated chitosan is 10-40%, the thickness of the gel layer is 0.1-5 mm, the antibacterial circle diameter is 1.1-1.4 cm, the equilibrium swelling rate is 110-220%, and the antioxidant rate is 60-90%. The water gel-like methacrylated chitosan coating layer is formed on the surface of the regenerated cellulose non-woven fabric, the antibacterial and antioxidant activities of the composite non-woven fabric are improved, meanwhile, the water gel-like coating layer contacts the skin wound, is beneficial to the moist healing of the wound, and can effectively inhibit the bacterial propagation and accelerate the skin wound healing. The modified non-woven fabric has excellent moisture absorption, moisture retention, antibacterial and antioxidant functions.

This invention relates to the field of fluoride-containing wastewater treatment technology, specifically to a method for preparing a high-efficiency composite defluoridating agent and its application. The composite defluoridating agent provided by this invention comprises a composite defluoridating core, a chitosan coating layer, and an F-imprinted outer layer. The composite defluoridating core is formed by in-situ co-precipitation of Mg-Al-La layered double hydroxides by chitosan complexing with Mg, Al, and La metal sources, and the introduction of TiO2 and MnO2 functional oxides. The chitosan coating layer coats the surface of the composite defluoridating core. The F-imprinted outer layer... ‑ The outer layer of the imprint is formed by pre-assembly, cross-linking, and template elution of fluoride ion template, quaternized chitosan, and chitosan. This invention also provides a composite defluorinating agent working solution obtained by mixing a double aluminum salt solution and a composite defluorinating agent dispersion, used for deep defluorination treatment of fluoride-containing wastewater containing competing anions of phosphate, silicate, bicarbonate, and / or carbonate, with advantages such as high defluorination efficiency, good selectivity, and strong anti-interference ability.

The present invention relates to the field of denture base materials, and provides a 3D printing high-strength oral denture base and a preparation method thereof. The denture base is prepared from the following components: titanium oxide composite microspheres coated with chitosan, surface modified boron nitride nanotubes coated with nano-silver particles, acrylic resin, polyetheretherketone, anhydrous ethanol, defoamer, dispersant, and photoinitiator. Preparation method: S1. Disperse fillers, and prepare a uniform mixed solution by ultrasonic and mechanical stirring; S2. Prepare a resin base liquid, add acrylic resin, polyetheretherketone and other materials and stir evenly; S3. Print and form, and use a DLP light-curing 3D printer to print the denture base; S4. Finishing, including demoulding, cooling and surface grinding treatment, finally obtaining a finished denture base. The present invention solves the strength and antibacterial problems of the denture base by combining titanium oxide composite microspheres with chitosan coating layers and surface modified boron nitride nanotubes coated with nano-silver particles, respectively, and has a wide range of application value.

The invention belongs to the technical field of fiber modification, and provides a chitosan modified nylon fiber as well as a preparation method and application thereof. The preparation method comprises the following steps: mixing chitosan with an acid solvent to obtain a chitosan solution; the preparation method comprises the following steps: soaking nylon fibers in a chitosan solution, and sequentially carrying out drying treatment and curing treatment after soaking is finished, so as to obtain the chitosan modified nylon fibers. Wherein the chitosan is a natural polysaccharide, is non-toxic and harmless and meets the environmental protection requirement, and meanwhile, harmful chemical substances are not used in the preparation process, so that the safety of the product is ensured; the chitosan modified nylon fiber has a remarkable antibacterial effect, and the chitosan coating on the surface of the nylon fiber can effectively inhibit growth and reproduction of various bacteria and fungi. The chitosan modified nylon fiber prepared by the invention can be widely applied to the fields of medical supply packaging or food packaging and the like, and has great market potential.

The invention discloses a tooth orthodontic bracket EGCG (epigallocatechin gallate)-based functional binder and a preparation method thereof in the field of binders. Comprising the following components in parts by weight: 25 to 30 parts of bisphenol A dimethacrylate, 15 to 20 parts of triethylene glycol dimethacrylate, 0.6 to 0.8 part of camphorquinone, 0.6 to 0.8 part of dimethylaminoethyl methacrylate, 3 to 5 parts of EGCG (epigallocatechin gallate) loaded nanoparticles and 6 to 8 parts of modified chitosan. Through the core structure design of loading EGCG (epigallocatechin gallate) on cationic nano silicon dioxide and coating modified chitosan for multiple times, the dual core advantages of accurate pH response controlled release and safe adaptation to the oral environment are realized in the application of the dental orthodontic bracket adhesive, the effect is supported by a clear mechanism, and release, bacteriostasis and toxicity test data verify that the dental orthodontic bracket adhesive has a good application prospect. The clinical application requirements are completely met.

The invention discloses a biodegradable antifungal composition as well as a preparation method and application thereof, and belongs to the technical field of antifungal products. The antifungal composition is prepared by loading cinnamyl aldehyde on cellulose and then packaging through a chitosan coating, the preparation method comprises the following steps: preparing a cellulose suspension, adding the cellulose suspension into an ethanol solution of cinnamyl aldehyde, uniformly stirring, filtering, precipitating and washing to obtain cinnamyl aldehyde cured cellulose; and adding the cinnamyl aldehyde cured cellulose into a chitosan solution, uniformly stirring, and after the cinnamyl aldehyde cured cellulose becomes yellow, filtering, precipitating and washing, and air-drying to a fixed weight, thereby obtaining the antifungal composition. The antifungal composition can be used for preparing antifungal products such as a fumigant, a coating, a soil conditioner and the like. The cinnamyl aldehyde in the antifungal composition disclosed by the invention can be kept stable and slowly released, so that the antifungal activity on plant pathogenic fungi is enhanced; the raw materials used for preparation are simple and natural, have the characteristic of degradability, and are environment-friendly.

The invention discloses a conductive hydrogel microneedle for multi-target nerve repair and a preparation method thereof, and relates to the field of traditional Chinese medicine, and the conductive hydrogel microneedle comprises the following main medicine components: astragaloside, ligustrazine, gastrodin, tenuigenin and edaravone. The preparation method comprises the following steps: preparing soybean lecithin, cholesterol and astragaloside into a lipid membrane; adding edaravone, ligustrazine and selenium nanoparticles to obtain a liposome; the preparation method comprises the following steps: biologically coupling liposome and a TfR-mAb solution to obtain a chitosan coating layer; the preparation method comprises the following steps: preparing gastrodin and tenuigenin into microspheres; uniformly mixing GelMA, SBMA, carboxylated nanocellulose, the chitosan coating layer and the microspheres, and then adding an LAP photoinitiator to prepare a mixed solution; and cleaning and blow-drying the filiform needle, placing the filiform needle in a PDMS mold, adding the mixed solution, carrying out vacuum defoaming, and then carrying out UV curing and packaging. According to the traditional Chinese medicine composition, qi deficiency and blood stasis and phlegm and blood stasis are integrated into the same prescription, and the limitation of traditional typing treatment is solved through ligustrazine and gastrodin.

The invention discloses a multi-probe grafted magnetic metal framework material, a preparation method and application of the multi-probe grafted magnetic metal framework material in enrichment of body fluid exosomes. The multi-probe grafted magnetic metal framework material is a material with a core-shell structure, the core of the material is a ferroferric oxide magnetic core, a shell layer of the material sequentially comprises a polydopamine coating, a zirconium-based organic metal framework shell layer and a chitosan coating from inside to outside, and two types of exosome recognition groups, namely an alkyl quaternary ammonium group and a phospholipid group, are grafted on the surface of the material. The material is a novel composite magnetic metal framework material formed by grafting alkyl quaternary ammonium and a phospholipid molecular probe on the surface of a zirconium-based organic metal framework material, and enrichment of exosomes in body fluid is realized through coordination, electrostatic adsorption and hydrophobic interaction.

The utility model discloses an anti-fog vehicle body sticker which comprises a base material layer, one side of the base material layer is coated with an anti-fog layer, the side, away from the anti-fog layer, of the base material layer is coated with a polyacrylate bonding layer, and the side, away from the base material layer, of the polyacrylate bonding layer is provided with a bottom layer. The anti-fog layer is an acrylic acid grafted chitosan coating; the acrylic acid grafted chitosan coating is also filled with boron nitride nanospheres and silicon dioxide nanospheres. The vehicle body sticker disclosed by the utility model has excellent anti-fog performance.