713results about "Hyaluronic acid coatings" patented technology

The present invention relates to processes utilizing ionic liquids for the dissolution of various polymers and / or copolymers, the formation of resins and blends, and the reconstitution of polymer and / or copolymer solutions, and the dissolution and blending of “functional additives” and / or various polymers and / or copolymers to form advanced composite materials.

An implantable stimulation electrode for use with an implantable tissue stimulator, especially a pacemaker, a defibrillator, a bone stimulator or a neurostimulator includes a metal base body, optionally one or more intermediate layers disposed on the base body and a coating covering the base body and, optionally, intermediate layers in order to increase tissue compatibility. The coating should prevent tissue irritations after implantation and more particularly increase the stimulus threshold associated therewith, have very high biocompatibility and also has an anti-inflammatory effect. An increase in tissue compatibility is achieved by virtue of the fact that the coating has a polysaccharide layer made of hyaluronic acid and / or hyaluronic acid derivatives.

A hard coat film includes a transparent plastic film substrate; and a hard coat layer, wherein the hard coat layer is formed of a composition for forming a hard coat layer, the composition containing the following component (A), component (B), and an organic solvent:Component (A): a polyrotaxane,Component (B): a monomer having two or more ethylenically unsaturated groups.

A solid surface material with an antimicrobial agent in a thermoset and / or thermoplastic resin matrix where the antimicrobial agent comprises a chitosan-metal complex.

The invention relates to the immobilization of polysaccharides on a substrate. In particular, the invention relates to biologically active surfaces formed by the immobilization of glycosaminoglycans on a substrate. The invention also provides biologically active surfaces that contain one or more different glycosaminoglycans and, optionally, one or more other agents. These agents can be biological or therapeutic agents. The invention also relates to methods of using the surfaces of the invention, such as, methods of affecting biological processes, eliciting patterns of cellular response, screening, treatment, diagnosis and preventing food contamination and / or spoilage.

The invention provides a network composition comprising a plurality of associated saccharide chains wherein a chain comprises at least one saccharide component; and at least one first monomer, at least one second monomer, or combinations of both; wherein the first monomer is linked to the saccharide component by ester linkages; ether linkages; amide linkages; ketone linkages; or combinations thereof; wherein the second monomer is linked to the saccharide component by ester linkages; ether linkages; amide linkages; ketone linkages; urea linkages; carbamate linkages, aluminum oxide linkages; siloxane linkages; or combinations thereof; wherein first monomers are linked to each other by ester linkages; ether linkages; amide linkages; ketone linkages; or combinations thereof; wherein the first monomer is linked to the second monomer by ester linkages; ether linkages; amide linkages; ketone linkages; urea linkages; carbamate linkages; aluminum oxide linkages; siloxane linkages or combinations thereof; wherein the second monomers are linked to each other by ester linkages; ether linkages; amide linkages; ketone linkages; polyvinyl linkages, polyolefin linkages, urea linkages; carbamate linkages, aluminum oxide linkages, siloxane linkages or combinations thereof; and wherein the saccharide components are linked to each other by ester linkages; ether linkages; amide linkages; ketone linkages; or combinations thereof; wherein the network is capable of adhering to a substrate.

The present invention provides methods of preventing the flow of water or gas or both through a subterranean zone having a high temperature and a depth such that a long pumping time is required to place a sealing composition therein. The methods basically comprise the steps of preparing a polymeric sealing composition comprised of water, a cross-linking agent and a selected water-soluble polymer which reacts with the cross-linking agent and forms a sealing gel which is stable for a desired period of time at the temperature of the zone and has a pumping time before gelation in the presence of the cross-linking agent whereby the composition can be pumped to the depth of the zone and placed therein. Thereafter, the sealing composition is pumped into the zone and allowed to form a sealing gel therein.

A hydrophilic coating can be applied to virtually any surface to produce a long-lasting, durable antifog effect. The coating can be biocompatible. The coating includes a molecular-level blend of hydrophilic polymers. The coating can be assembled using a layer-by-layer assembly process.

The present application discloses methods for repairing hyaline cartilage defects. The methods comprise a combination of introducing autologous bone mesenchymal stem cells to a joint, and applying to the joint a membrane comprising a polyester entangled with a polysaccharide. In some aspects, the bone mesenchymal stem cells are mesenchymal stem cells originating in bone underlying the joint. In these aspects, contact between the joint and the mesenchymal stem cells can be effected by introducing apertures through the bone using standard surgical techniques such as microfracture, abrasion, or drilling. Cartilage which forms in response to application of these methods is hyaline cartilage rather than fibrocartilage.

Fragmented polysaccharide based hydrogel compositions and methods of making and using the same are provided. The subject polysaccharide based hydrogel compositions are prepared by combining a polysaccharide component with a hydrophilic polymer and a cross-linking agent. Also provided are kits and systems for use in preparing the subject compositions.

The invention relates to a method for preparing a chitosan-based composite preservative film or a coating, belonging to the technical field of food preservation. According to the technical scheme, the method comprises the following steps: dissolving chitosan in an aqueous solution of acetic acid, adding an aqueous solution of natural active substances with antioxidant and antibacterial functions, heating, stirring and ultrasonically defoaming to obtain the chitosan-based composite preservative film or a coating film solution; casting and drying the chitosan-based composite preservative film or the coating film solution to obtain a chitosan-based composite preservative film; and coating the chitosan-based composite preservative film or the coating film solution on the surface of food so as to obtain the chitosan-based composite preservative coating. According to the prepared chitosan-based composite preservative film or the coating, the antibacterial performance and the moisture resistance of the chitosan film are improved, and the chitosan-based composite preservative film or the coating is endowed with novel antioxidant functions and has degradable and edible characteristics. When meat, oil or fruit and vegetable foods are packaged or coated by the obtained chitosan-based composite preservative film or the coating, the quality guarantee period can be effectively prolonged, and the chitosan-based composite preservative film or the coating has wide application prospect.

Water-based, substrate treatment compositions contain (A) at least one chitosan selected from chitosan and a chitosan derivative, and (B) a metal compound containing at least one metal selected from Ti, Zr, Hf, Mo, W, Se, Ce, Fe, Cu, Zn, V and trivalent Cr. In particular, the water-based, substrate treatment compositions can improve the interlayer adhesion between metal materials and resin coating layers such as films or coatings, and can also improve the corrosion resistance and solvent resistance of such metal materials.

The present invention relates to processes utilizing ionic liquids for the dissolution of various polymers and / or copolymers, the formation of resins and blends, and the reconstitution of polymer and / or copolymer solutions, and the dissolution and blending of “functional additives” and / or various polymers and / or copolymers to form advanced composite materials.

The invention is directed to a method and composition for providing chemically-resistant roughened copper surfaces suitable for subsequent multilayer lamination. In one embodiment, a smooth copper surface is contacted with an adhesion promoting composition under conditions effective to provide a roughened copper surface, the adhesion promoting composition comprising an oxidizer, a pH adjuster, a topography modifier, and a sulfur-containing coating stabilizer. In another embodiment, a smooth copper surface is contacted with an adhesion promoting composition under conditions effective to provide a roughened copper surface, the adhesion promoting composition comprising an oxidizer, a pH adjuster, and a topography modifier. Then, in a subsequent step, the roughened copper surface is contacted with an acid resistance promoting composition.

A coating composition that is incorporated into a facemask to reduce fogging and glare is provided. For example, in one embodiment, the facemask contains a shield or visor formed from a transparent substrate having at least one surface applied with the coating composition of the present invention. The present inventors have unexpectedly discovered that one or more water-soluble organic polymers, such as ethyl hydroxyethylcellulose, may be utilized as a principal component of the coating composition to reduce fogging and glare in a simple, yet effective manner.

Embodiments of the technology relate to a contact lens having a core that is covalently coated by a hydrogel layer, and to methods of making such a lens. In one aspect, embodiments provide for a coated contact lens comprising a lens core comprising an outer surface; and a hydrogel layer covalently attached to at least a portion of the outer surface, the hydrogel layer adapted to contact an ophthalmic surface, wherein the hydrogel layer comprises a hydrophilic polymer population having a first PEG species and a second PEG species, the first PEG species being at least partially cross-linked to the second PEG species.

A coating composition that is incorporated into a facemask to reduce fogging and glare is provided. For example, in one embodiment, the facemask contains a shield or visor formed from a transparent substrate having at least one surface applied with the coating composition of the present invention. The present inventors have unexpectedly discovered that one or more water-soluble organic polymers, such as ethyl hydroxyethylcellulose, may be utilized as a principal component of the coating composition to reduce fogging and glare in a simple, yet effective manner.

The invention discloses a marine anticorrosive coating, comprising the following components in parts by weight: 100 parts of water-based epoxy resin emulsion, 5-16 parts of waterborne polyurethane, 1-2.5 parts of modified asphalt, 5-10 parts of a waterborne epoxy curing agent, 10-30 parts of modified nano titanium dioxide, 5-16 parts of modified carbon nanotubes, 5-15 parts of red iron oxide, 3-5 parts of zinc powder, 2-15 parts of fiber fluff, 0.9-2.5 parts of chitosan, 3-8 parts of a coalescing agent, 0.5-1.3 parts of a defoaming agent, 0.3-1.5 parts of a wetting agent, 0.6-1.5 parts of a dispersing agent, 0.5-1.6 parts of a flatting agent, 0.2-0.8 part of a thickener and 5-15 parts of water. The marine anticorrosive coating disclosed by the invention is strong in anti-corrosion property, good in impact resistance, easy to construct, and long in service life when being applied to marine equipment.

Metal nanowires with uniform noble metal coatings are described. Two methods, galvanic exchange and direct deposition, are disclosed for the successful formation of the uniform noble metal coatings. Both the galvanic exchange reaction and the direct deposition method benefit from the inclusion of appropriately strong binding ligands to control or mediate the coating process to provide for the formation of a uniform coating. The noble metal coated nanowires are effective for the production of stable transparent conductive films, which may comprise a fused metal nanostructured network.

A biocompatible polymeric composition for cross-linking in-situ in a wound is disclosed comprising 1) one or more polyanionic polymers such as alginates or hyaluronates, able to be cross-linked the surface of the wound and 2) one or more polycationic polymers such as chitosan or DEAE-Dextran, that assists in the solidification process as well as speeds up hemostasis without the need for applying pressure. The biocompatible polymeric composition may further comprise a cross-linking agent such as aqueous calcium chloride. The invention encompasses an initial polymeric composition, the solidified matrix cross-linked and integrated at the wound site, including the methods of using, applying, and cross-linking the composition.

The invention discloses a polyelectrolyte nanometer flame-retardant coating by adoption of layer-by-layer assembly and a preparation method thereof. The preparation method comprises following steps of: 1), preprocessing: putting and soaking base material into an acid solution and cleaning and drying base material with water; 2), self-assembly: putting and soaking pre-processed base material to a cationic polyelectrolyte solution in order to from a layer of ion membrane, taking out the layer of ion membrane and cleaning the ion membrane with water for drying, putting and soaking the ion membrane into the cationic polyelectrolyte solution in order to form an layer of anionic membrane, and cleaning the layer of anionic membrane with water and drying; sequentially repeating above self-assembly process for multiple times so that the polyelectrolyte nanometer flame-retardant coating is prepared by adoption of layer-by-layer assembly on the surface of the base material. The polyelectrolyte nanometer flame-retardant coating by adoption of layer-by-layer assembly and the preparation method thereof have following beneficial effects: the polyelectrolyte nanometer flame-retardant coating is green and eco-friendly and has a simple and feasible preparation method; damage to the internal structure of base material is avoided; high flame-retardant efficiency is obtained; and the preparation method is suitable for formation of flame-retardant coatings on material surfaces including fabric, wood, foam and plastics.

The present invention relates to formaldehyde eliminating green water-base lacquer and its preparation process. The formaldehyde eliminating green water-base lacquer as one kind of chemical paint composition is used for surface treatment of wooden furniture. It consists of polymer emulsion, filming assistant, foam inhibitor, wetting and leveling agent, thickener, preservative, pure water and other ingredients. Owing to its formaldehyde eliminating ingredients, the formaldehyde eliminating green water-base lacquer is one kind of excellent water-base lacquer with excellent formaldehyde eliminating effect.

The present invention relates to a barrier layer and a packaging laminate comprising a barrier layer and a method to produce a barrier layer. The barrier layer is manufactured of a cellulose-based hydrolysate. The barrier layer comprises lignin and oligo- or poly-saccharides, where the lignin and oligo- or polysaccharides are at least partly covalently bonded to each other in a matrix, and at least one co-component. The co-component is bonded to the lignin and oligo- or polysaccharides by means of primary and / or secondary bonds. In addition, the invention relates to a package made of the packaging laminate.

The invention discloses a nanocomposite road marking coating material. The nanocomposite road marking coating material comprises the following ingredients in parts by weight: 20-30 parts of glass powder, 6-10 parts of aluminum oxide powder, 50-80 parts of filler, 30-40 parts of epoxy resin, 15-20 parts of aqueous epoxy modified acrylate, 15-20 parts of glass micro-beads, 10-20 parts of chitin, 15-20 parts of chitosan, 20-40 parts of nano titanium white, 15-20 parts of nano zinc oxide, 10-15 parts of nano-silica, 2-4 parts of 25wt% ammonia water, 30-40 parts of acrylic emulsion and 15-20 parts of nano rare-earth self-luminous material. The invention further discloses a preparation method of the nano coating material. The nanocomposite road marking coating material disclosed by the invention is high in drying speed and long in service life, is wear-resistant and anti-fouling and has a bacterium resisting effect, and nano-materials or nano-structured ingredients are introduced into an organic coating material, so that organic and inorganic matched compositing or hybridization is realized. The advantages of organic polymers and inorganic-structured ingredients are integrated, so that the properties of the coating material are obviously improved.

A water-based slurry composition contains (1) a water-based medium containing at least water as a polar solvent, (2) at least one polymer selected from cellulose derivatives, alginic acid derivatives, starch derivatives, chitin derivatives, chitosan derivatives, polyallylamine and polyvinylamine, (3) a hydrophobic filler, and (4) a polybasic acid or a derivative thereof. The composition has a water content of 30 mass % or higher. An electrode plate for an electricity storage device, and the electricity storage device are also disclosed.

The invention discloses a diatomite coating capable of decomposing formaldehyde and relates to the field of coatings. The diatomite coating comprises the following components in percentage by mass: 5%-15% of titanium dioxide, 3%-10% of nano-titanium dioxide, 2%-8% of white carbon black, 1%-3% of nano-calcium carbonate, 2%-5% of nano-silicon dioxide, 6%-18% of nano-tungsten trioxide, 2%-8% of sepiolite material, 5%-7% of chitin, 3%-6% of graphene oxide, 0.5%-1.3% of mica powder, 1%-7% of nano-activated carbon, 0.1%-0.5% of a phthalocyanin compound and the balance of diatomite. The diatomite in the diatomite coating is capable of quickly decomposing organic compounds, purifying air and effectively improving the quality of indoor air; meanwhile, the indoor negative ion concentration can be increased, which is beneficial to the human body health.

The invention provides polyelectrolyte hydrogels, blends, and multilayers for the controlled release of bioactive agents from implantable medical devices coated with or containing such media.

The present invention concerns multilayer films comprising a plurality of layers, at least some of the layers comprise (i) cross-linked chitosan, alginate, chondroitin sulfate, or hyaluronic acid and (ii) particles or void spaces; wherein the layers are 20-260 nm in thickness. Also disclosed are multilayer films comprising at least two of: a layer comprising a first polymer; a layer comprising a second polymer; a layer comprising particles, wherein said particles comprise ceramic material, metallic species, or both; and, a layer comprising a combination of said first polymer and said particles; wherein said multilayer film is capable of displaying structural color. Also provided are methods for making and using the inventive multilayer films and compositions comprising the multilayer films.

A nucleic acid coating composition including a polyanion bound, directly or through one or more intermediates, to a medical device surface, with a condensate comprising a polycation and nucleic acid bound to the polyanion, devices incorporating such coating compositions, and methods for making. In one embodiment, a silyl-heparin complex is provided, bound to a medical device surface by hydrophobic interaction with the silyl moiety, with a polycation and nucleic acid condensate bound to the heparin by electrostatic interaction.

An electrode sensor kit for establishing electrical contact with skin comprises at least one contact element and a preparation comprising a mixture of water and at least one lipid for enhancing electrical contact properties between said contact element and the skin, wherein said mixture forms an emulsion, in particular a water-in-oil or an oil-in-water emulsion, having a conductivity of less than 3 mS / cm. An electrode assembly for electrical impedance tomography which comprises said kit is characterized in that (a) said at least one contact element forms an electrode or sensor plate, and (b) said at least one contact element comprises a layer of said preparation.