52results about "Heparin adhesives" patented technology

The present invention relates to processes utilizing ionic liquids for the dissolution of various polymers and / or copolymers, the formation of resins and blends, and the reconstitution of polymer and / or copolymer solutions, and the dissolution and blending of “functional additives” and / or various polymers and / or copolymers to form advanced composite materials.

A solid surface material with an antimicrobial agent in a thermoset and / or thermoplastic resin matrix where the antimicrobial agent comprises a chitosan-metal complex.

The present invention provides methods of preventing the flow of water or gas or both through a subterranean zone having a high temperature and a depth such that a long pumping time is required to place a sealing composition therein. The methods basically comprise the steps of preparing a polymeric sealing composition comprised of water, a cross-linking agent and a selected water-soluble polymer which reacts with the cross-linking agent and forms a sealing gel which is stable for a desired period of time at the temperature of the zone and has a pumping time before gelation in the presence of the cross-linking agent whereby the composition can be pumped to the depth of the zone and placed therein. Thereafter, the sealing composition is pumped into the zone and allowed to form a sealing gel therein.

The present application discloses methods for repairing hyaline cartilage defects. The methods comprise a combination of introducing autologous bone mesenchymal stem cells to a joint, and applying to the joint a membrane comprising a polyester entangled with a polysaccharide. In some aspects, the bone mesenchymal stem cells are mesenchymal stem cells originating in bone underlying the joint. In these aspects, contact between the joint and the mesenchymal stem cells can be effected by introducing apertures through the bone using standard surgical techniques such as microfracture, abrasion, or drilling. Cartilage which forms in response to application of these methods is hyaline cartilage rather than fibrocartilage.

Water-based, substrate treatment compositions contain (A) at least one chitosan selected from chitosan and a chitosan derivative, and (B) a metal compound containing at least one metal selected from Ti, Zr, Hf, Mo, W, Se, Ce, Fe, Cu, Zn, V and trivalent Cr. In particular, the water-based, substrate treatment compositions can improve the interlayer adhesion between metal materials and resin coating layers such as films or coatings, and can also improve the corrosion resistance and solvent resistance of such metal materials.

The present invention relates to processes utilizing ionic liquids for the dissolution of various polymers and / or copolymers, the formation of resins and blends, and the reconstitution of polymer and / or copolymer solutions, and the dissolution and blending of “functional additives” and / or various polymers and / or copolymers to form advanced composite materials.

A biocompatible polymeric composition for cross-linking in-situ in a wound is disclosed comprising 1) one or more polyanionic polymers such as alginates or hyaluronates, able to be cross-linked the surface of the wound and 2) one or more polycationic polymers such as chitosan or DEAE-Dextran, that assists in the solidification process as well as speeds up hemostasis without the need for applying pressure. The biocompatible polymeric composition may further comprise a cross-linking agent such as aqueous calcium chloride. The invention encompasses an initial polymeric composition, the solidified matrix cross-linked and integrated at the wound site, including the methods of using, applying, and cross-linking the composition.

An electrode sensor kit for establishing electrical contact with skin comprises at least one contact element and a preparation comprising a mixture of water and at least one lipid for enhancing electrical contact properties between said contact element and the skin, wherein said mixture forms an emulsion, in particular a water-in-oil or an oil-in-water emulsion, having a conductivity of less than 3 mS / cm. An electrode assembly for electrical impedance tomography which comprises said kit is characterized in that (a) said at least one contact element forms an electrode or sensor plate, and (b) said at least one contact element comprises a layer of said preparation.

A solid surface material with an antimicrobial agent in a thermoset and / or thermoplastic resin matrix where the antimicrobial agent comprises a chitosan-metal complex.

Water-based, substrate treatment compositions contain (A) at least one chitosan selected from chitosan and a chitosan derivative, and (B) a metal compound containing at least one metal selected from Ti, Zr, Hf, Mo, W, Se, Ce, Fe, Cu, Zn, V and trivalent Cr. In particular, the water-based, substrate treatment compositions can improve the interlayer adhesion between metal materials and resin coating layers such as films or coatings, and can also improve the corrosion resistance and solvent resistance of such metal materials.

A colored particle (e.g., a spherical particle) comprising an organic solid component (e.g., a polymer component) and a coloring agent (e.g., an oil-soluble dye, and an organic or inorganic pigment) is produced by eluting a water-soluble auxiliary component comprising at least an oligosaccharide from a composition having a disperse system, in which a particulate dispersed phase comprising the organic solid component and the coloring agent is dispersed in a matrix comprising the auxiliary component. The weight ratio of the polymer component relative to the auxiliary component may be about 55 / 45 to 1 / 99. The proportion of the coloring agent may be about 0.001 to 100 parts by weight relative to 100 parts by weight of the organic solid component. Such a process ensures conveniently and industrially advantageous production of a colored particle (e.g., a colored polymer particle) corresponding to the dispersed phase independently of affinity between the dispersed phase and the matrix.

The invention relates to a polymer composition comprising a biologically degradable polymer and a material from sea plants and / or shells of sea animals or at least two components selected from the group consisting of saccharides and the derivatives thereof, proteins, amino acids, vitamins and metal ions. The invention additionally relates to a molded article comprising said polymer composition. Said molded article may be used packaging material or fibrous material, in the form of fibrous material as mixing component for the production of yarns, and in the form of fibrous material for the production of nonwoven fabrics or woven fabrics.

The present application discloses methods for repairing hyaline cartilage defects. The methods comprise a combination of introducing autologous bone mesenchymal stem cells to a joint, and applying to the joint a membrane comprising a polyester entangled with a polysaccharide. In some aspects, the bone mesenchymal stem cells are mesenchymal stem cells originating in bone underlying the joint. In these aspects, contact between the joint and the mesenchymal stem cells can be effected by introducing apertures through the bone using standard surgical techniques such as microfracture, abrasion, or drilling. Cartilage which forms in response to application of these methods is hyaline cartilage rather than fibrocartilage.

Disclosed is a foaming material composite including a water-soluble polysaccharide having ester linkage or amide linkage, a foaming agent, and a plasticizing agent.

A polymer blend is prepared by dissolving chitosan and a second polymer in an acidic aqueous solution to form an aqueous polymer blend, dehydrating said aqueous polymer blend, and recovering said polymer blend. The second polymer may be selected from the group consisting of polyether glycols including polyethylene glycols; cellulose esters including cellulose acetate; poloxamers; polysaccharides including dextran and guar; polyvinylpyrrolidones; polyvinyl alcohols; and mixtures or copolymers thereof. These polymer blends swell in an acidic environment and deswell in a more neutral or basic environment. This technology is valuable for the dispensing of biologically active material or drugs into a surrounding environment, especially the environment as is found in the gastrointestinal tract. Since the various polymer blends of the present invention are not covalently or ionically crosslinked, but are physically combined, each polymer in the physical blend maintains its original chemical structure, and therefore, is safe for oral administration.

Disclosed is a cellulose ester film which is suppressed in volatilization of components during film formation, while having high surface flatness, high durability after saponification and good adhesion to a polarizer. Also disclosed is a method for producing such a cellulose ester film by melt forming. Further disclosed are a polarizing plate having high light resistance and high durability, and a liquid crystal display having high image quality. Specifically disclosed is a cellulose ester film characterized by containing a cellulose ester, a compound represented by the general formula (1) below, and a compound represented by the general formula (2) below.

The invention provides compositions and methods for in situ repair of compromised polymeric membranes. The invention is useful for repairing compromised polymeric membranes without requiring the knowledge of damage location or the disassembly of a system. The invention relates to preferential blocking of damaged sites using agglomerates and subsequent cross-linking to form sturdy plugs.

Binder including (i) a chitosan derivative and (ii) deionized water or 1 vol. % aqueous solution of acetic acid as a dispersant. A method for preparing an electrode of a lithium ion battery by adding the binder to a conductive agent.

A composition-of-matter is provided. The composition-of-matter comprising a chelator moiety-hyaluronan complex bound to a solid support. Also provided are methods of in-situ assessing hyaluronidase activity using such compositions.

The present invention relates to a method of manufacturing soil reinforced by microbe-based bio-binders and soil produced by the method. The bio-binders are not harmful to humans, do not cause environmental pollution and secure sufficiently the soil strength and resistance against wind. According to the method, the soil is prepared by binding sand whose major components are silica and alumina, ureolytic microbes, urea, calcium ion, and polymer fibers, and the content of polymer fibers in sand ranges from 0.05 wt % to 5 wt %. In addition, it is preferable that the microbes provide CaCO3 at a rate at 1˜7×10−9 g CaCO3 ppt cell−1 hr−1 under optimum conditions.

The present invention relates to a process of using a heat responsive mixture to produce inorganic interconnected 3D open-cell bone substitutes which can be applied in the orthopedic or dental field for treatment of bone damage. The invention provides a simple and easily-controlled process of preparing porous inorganic bone substitute materials.

The invention relates to a polymer composition comprising a biologically degradable polymer and a material from sea plants and / or shells of sea animals or at least two components selected from the group consisting of saccharides and the derivatives thereof, proteins, amino acids, vitamins and metal ions. The invention additionally relates to a molded article comprising said polymer composition. Said molded article may be used packaging material or fibrous material, in the form of fibrous material as mixing component for the production of yarns, and in the form of fibrous material for the production of nonwoven fabrics or woven fabrics.

Use of an aqueous composition, which has been prepared by dissolving (A) dihydroxypropylchitosan and (B) 1,2,3,4-butanetetracarboxylic acid (B) in an aqueous medium, makes it possible to provide articles excellent in hydrophilicity, antibacterial and deodorant activities, touch feeling, antifogging property, paper strength, dyeability, waterproofness, antifouling property and / or the like.

The present invention relates to a process for preparing a porous hybrid comprising zeolite and chitosan and a porous hybrid prepared thereby, in particular, to a process for preparing a porous chitosan-linking compound-zeolite hybrid, which comprises the steps of: (a) forming a linking compound-zeolite intermediate by linking a linking compound to the surface of zeolite; and (b) preparing said chitosan-linking compound-zeolite hybrid by reacting said linking compound-zeolite intermediate with chitosan or a linking compound-chitosan, a porous hybrid prepared thereby, an adsorbent and a method for purifying water.

This invention relates to a composition characterized by containing, as essential components, deacetylated chitin and / or a deacetylated chitin derivative, and glyoxylic acid; a solution-containing gel formed from the composition; a water-insoluble chitosan coating; and a material obtained by treating a base material with the composition. According to the present invention, it is possible to provide a chitosan composition, which in a “one-pack” form, has a pot life. Even when dried at room temperature after coating or impregnation of a base material, the chitosan coating can be water-insolubilized with reduced yellowing.

The invention relates to a new hyaluronan derivative according to the general formula (I), the method of preparation thereof, a hydrogel based on the new derivative, method of preparation of the hydrogel and the use of the hydrogel in tissue engineering, cosmetics, medicine or regenerative medicine, especially in the form of scaffolds for the treatment of articular cartilage or bone tissue defects.

Disclosed is a cellulose ester film which is suppressed in volatilization of components during film formation, while having high surface flatness, high durability after saponification and good adhesion to a polarizer. Also disclosed is a method for producing such a cellulose ester film by melt forming. Further disclosed are a polarizing plate having high light resistance and high durability, and a liquid crystal display having high image quality. Specifically disclosed is a cellulose ester film characterized by containing a cellulose ester, a compound represented by the general formula (1) below, and a compound represented by the general formula (2) below.

It is an object of the present invention to provide a spinning solution for industrial production of pure chitosan fiber and the method for fabricating the same. The method comprises the steps of: step (a): screening a flake chitosan raw material and removing impurities; step (b): putting in a dissolving kettle the screened flake chitosan raw material with a weight which is 3%-8% of the total weight of the spinning solution, sealing the dissolving kettle, and evacuating into vacuum; step (c): adding 0.9%-6% acetic acid solution, and soaking at the room temperature for 40-60 minutes; step (d): uniformly stirring at a rate of 26-60 rpm for 7.5-19 hours under a pressure of ≦5000 pa in the dissolving kettle, standing for 1-3 hours, and obtaining a spinning solution. By using this method, it is possible to not only maintain the original state structure of the molecular chain of chitosan, but also fast and uniformly dissolve flake chitosan and the spinning solution fabricated by this method in unit time, so as to meet the requirements in the industrial continuous production.

A colored particle (e.g., a spherical particle) comprising an organic solid component (e.g., a polymer component) and a coloring agent (e.g., an oil-soluble dye, and an organic or inorganic pigment) is produced by eluting a water-soluble auxiliary component comprising at least an oligosaccharide from a composition having a disperse system, in which a particulate dispersed phase comprising the organic solid component and the coloring agent is dispersed in a matrix comprising the auxiliary component. The weight ratio of the polymer component relative to the auxiliary component may be about 55 / 45 to 1 / 99. The proportion of the coloring agent may be about 0.001 to 100 parts by weight relative to 100 parts by weight of the organic solid component. Such a process ensures conveniently and industrially advantageous production of a colored particle (e.g., a colored polymer particle) corresponding to the dispersed phase independently of affinity between the dispersed phase and the matrix.