The invention discloses a medical micro-fracture tool kit, the medical micro-fracture tool kit comprises a guide, a flexible soft drill and a medicine pushing and injecting rod which are connected with the guider in a matched mode. The guider comprises a toothed head end, an outer sleeve and a handle part, the interiors of the outer sleeve and the handle part are of cavity structures, one end of the outer sleeve is connected with the toothed head end into a whole, the other end of the outer sleeve is sleeved with the handle to be connected, and an included angle of 0-180 degrees is formed between the toothed head end and the outer sleeve. The flexible soft drill comprises a drill bit, a spring, a soft drill rod part and a soft drill handle part which are connected in sequence, a tough inner core is arranged in the soft drill rod part, and the drill bit can be bent to be matched with the guiders at different angles by combining with the spring. Clinically, a 30-degree guider, a 60-degree guider and a 90-degree guider are commonly used. The flexible soft drill can be matched with the guiders at different angles, multi-angle and accurate drilling can be achieved, fibrocartilage osteogenesis is improved, and the curative effect is greatly improved.