208results about How to "Antioxidant" patented technology

The invention belongs to the technical field of preparation of microorganisms and cosmetics, and particularly relates to a strain composition, radix paeoniae rubra fermentation liquor prepared from the strain composition and application of the strain composition in cosmetics. Specifically, Pseudoalteromonas sp. SE9 and Schizoscharomyces pombe JM2-16 are utilized to perform fermentation treatment on radix paeoniae rubra root powder, and the finally obtained radix paeoniae rubra fermentation liquor has multiple effects of resisting oxidation, promoting proliferation and migration of keratinocytes, promoting skin injury repair, resisting allergy, resisting inflammation, relieving and the like, is high in safety, can be used as a cosmetic component, and can be used as a cosmetic preparation. Therefore, the method has good practical application value.

The invention relates to a natural plant extract food antioxidant additive and a preparation method thereof, the natural plant extract food antioxidant additive comprises a core material and a wall material, and the core material comprises the following components by mass: 10-20 parts of a polyphenol compound, 10-15 parts of a polysaccharide compound and 20-30 parts of a flavonoid compound. The preparation method comprises the following steps: mixing sodium alginate and a polysaccharide compound to prepare a polysaccharide microcapsule; mixing a polyphenol compound, a flavonoid compound and the polysaccharide micro-capsule, and dispersing with an emulsifier to obtain an emulsified dispersion liquid; and mixing a chitosan solution and a polylysine solution to obtain a mixed wall material solution, adding the mixed wall material solution into the emulsified dispersion liquid to prepare a microcapsule product, washing, and freeze-drying to obtain the food antioxidant additive of the natural plant extract. The additive has the effect of improving the anti-oxidation performance, can provide long-acting and lasting anti-oxidation protection, and has a certain health-care effect.

The invention belongs to the technical field of microorganisms. The invention relates to a probiotic composition and application thereof in preparation of products for preventing and / or treating health conditions such as anti-tumor treatment related diarrhea. The probiotic composition comprises the following active ingredients: bifidobacterium bifidum, enterococcus faecalis, lactobacillus salivarius, lactobacillus fermentum mucus and parabacteroides didysonii. The probiotic composition has good safety, self-agglutination capability, oxidation resistance, short-chain fatty acid production capability, in-vitro cell adhesion capability, capability of inhibiting a plurality of pathogenic bacteria, capability of treating anti-tumor treatment related diarrhea and the like.

The invention discloses a preparation method of a multifunctional polyvinyl composite film and application of the multifunctional polyvinyl composite film in food preservation. The preparation method comprises the following steps: firstly, preparing Ag-coated MOF through a hydrothermal method, then uniformly dispersing the Ag-coated MOF and tannic acid into a carboxymethyl chitosan solution, and carrying out crosslinking modification on the Ag-coated MOF; and coating the prepared CMCS / TA / Ag (at) MOF mixed solution on a polyethylene film treated by oxygen plasma, and drying to form a film, so as to obtain the multifunctional polyethylene-based composite film. The CMCS and the TA are adopted to perform crosslinking modification on the Ag-coated MOF, so that the stability of the Ag-coated MOF can be further improved, and the release of silver ions is reduced. Compared with a common PE preservative film, the composite film prepared on the basis has better barrier capacity and mechanical property, and has antibacterial, anti-ultraviolet and anti-oxidation effects. The multifunctional preservative film is convenient to use and low in price, and has an important application prospect in the aspect of fresh-keeping packaging of meat products.

The invention discloses a concentric umbilical cable for an unmanned aerial vehicle and a preparation method thereof, and relates to the technical field of umbilical cables for unmanned aerial vehicles. The cable insulation layer is optimized, the overall weight of the cable is reduced, and the mechanical performance of the cable is enhanced. In the process, a macromolecular voltage stabilizer is innovatively adopted, and the problem that a traditional micromolecular voltage stabilizer is easy to separate out is effectively avoided. In order to improve the compatibility of the macromolecular voltage stabilizer in polypropylene, the macromolecular voltage stabilizer is further subjected to grafting treatment through allyl amine.

The invention discloses a preparation method of a polyphenol-containing medical adhesive. The preparation method comprises the following steps: respectively preparing a gelatin solution, a gallic acid solution and a tea polyphenol solution; mixing the gelatin solution and the gallic acid solution, and reacting at 40-60 DEG C for 6-12 hours to obtain a modified gelatin solution; mixing the tea polyphenol solution with the modified gelatin solution, adding an alkaline solution to adjust the pH value to 6.5-8.0, and uniformly mixing to obtain a mixed solution; the mixed solution is aged at 20-40 DEG C, water generated in the aging process is removed, and the polyphenol-containing medical adhesive is obtained. According to the preparation method of the polyphenol-containing medical adhesive, a gelatin protein molecular chain is used as a framework material, gallic acid is introduced into the protein molecular chain, tea polyphenol is used as a main chain cross-linking agent, the polyphenol-containing medical adhesive is prepared, a phenolic hydroxyl group can penetrate through a water boundary layer on the surface of a base material to form an adhesive bond with the base material, and the medical adhesive has the advantages that the water boundary layer can penetrate through the water boundary layer; good wet adhesion is shown on tissues.

The invention provides an anti-allergy soothing sanitary towel composite chip containing a purslane component and a preparation method, and belongs to the technical field of sanitary towels. The composite chip is of a multi-layer structure, the middle layer is a water absorption layer, the upper layer is an anti-allergy soothing layer, and the lower layer is a water-resisting layer; the anti-allergy soothing layer is a nanofiber membrane loaded with probiotic microspheres and a purslane extract, and the water-resisting layer is a polyethylene film or a polypropylene film; the water absorption layer is a composite layer of silicon dioxide aerogel and polyurethane sponge. The prepared anti-allergy soothing sanitary towel composite chip containing the purslane component not only has various biological functions of absorption, deodorization, peculiar smell removal, antibiosis, anti-inflammation, anti-allergy soothing, antioxidation, adjustment of ecological balance of private parts and the like, so that the effects of relieving itching and allergy, protecting skin barriers, resisting inflammation and the like are achieved, vaginal flora can be adjusted, and the effects of relieving itching, relieving itching, relieving inflammation and the like are achieved. And vaginitis and the like are reduced, the private health of women in the menstrual period is protected, and the health of women is facilitated.

The invention provides a traditional Chinese medicine composition for preventing and treating gout of goslings and a preparation method of the traditional Chinese medicine composition, and relates to the technical field of gosling breeding. The traditional Chinese medicine composition for preventing and treating gout of goslings comprises a composition I, a composition II and a composition III, the composition I is prepared from the following components in parts by weight: 70 to 90 parts of cortex cinnamomi, 30 to 50 parts of cortex phellodendri, 30 to 50 parts of rhizoma atractylodis, 40 to 60 parts of semen coicis, 20 to 40 parts of radix astragali seu hedysari and 20 to 40 parts of radix scutellariae; the composition II is prepared from the following components in parts by weight: 0 to 30 parts of radix bupleuri, 0 to 30 parts of radix angelicae sinensis and 0 to 30 parts of fructus lycii; the composition III is prepared from the following components in parts by weight: 0 to 20 parts of honeysuckle flower and 0 to 20 parts of herba taraxaci. The cortex cinnamomi, the semen coicis, the cortex phellodendri, the rhizoma atractylodis, the radix astragali seu hedysari and the radix scutellariae are added into the raw materials, so that the gout case fatality rate can be remarkably reduced on the basis of the prior art (the Simiao pill prescription), and the production benefit can be improved.

The invention discloses a polyphenylene sulfide fiber pps filter bag, and relates to the technical field of filter materials. The invention discloses a preparation method of a polyphenylene sulfide fiber pps filter bag, which comprises the following steps: carrying out melt extrusion granulation on polyphenylene sulfide and modified silicon dioxide to obtain granules; carrying out melt-blowing spinning, heat setting and hot rolling on the granules to obtain a pps filter bag; the modified silicon dioxide is obtained by modifying aminated mesoporous silicon dioxide with ethylenediamine tetraacetic anhydride and then carrying out epoxy treatment with epichlorohydrin. The prepared modified silicon dioxide is added into polyphenylene sulfide for granulation and melt-blowing treatment, the obtained polyphenylene sulfide fiber has the advantage of being good in mechanical property, the prepared polyphenylene sulfide fiber is used for preparing a pps filter bag, the prepared filter bag is applied to filtering treatment of high-temperature flue gas, the advantages of oxidation resistance and cross-linking resistance are achieved, and the application prospect is wide. And high filtering precision and trapping effect are achieved when smoke is filtered in a hot oxygen environment.

The invention discloses a bitter buckwheat health wine with antioxidant properties and a preparation method thereof, and belongs to the technical field of liquor production. The preparation method of bitter buckwheat health wine comprises the following steps: using bitter buckwheat grains as raw materials, washing, soaking, draining and crushing the bitter buckwheat grains, extracting the bitter buckwheat grains once by percolation extraction to obtain bitter buckwheat extract and raw material residues; using the expanded and domesticated honeysuckle mycelium to perform secondary fermentation and secondary percolation extraction on the raw material residues, and the three extracts are respectively concentrated and vacuum freeze-dried and then mixed to obtain bitter buckwheat dry matter. Secondly, sorghum and corn are used as raw materials, and distiller's yeast is added for saccharification and fermentation to obtain base wine. Finally, the bitter buckwheat mixed dry matter is compounded with the base wine to obtain bitter buckwheat health wine with antioxidant properties. The bitter buckwheat wine obtained by the invention has antioxidant capacity, has both the nutritional components of honeysuckle and the unique flavor of bitter buckwheat, and has excellent taste.

The invention relates to preparation and application of a wearable hydrogel sensor for strain and temperature dual-mode monitoring, and the preparation method comprises the following steps: 1, mixing acrylamide, N, N-methylene bisacrylamide, PEDOT: PSS, beta-cyclodextrin and gallic acid; step 2, after mixing, putting the mixture into a mixed solution of glycerol and deionized water, and uniformly stirring at normal temperature to obtain a conductive hydrogel precursor solution; 3, adding ammonium persulfate into the hydrogel precursor solution, and uniformly mixing to obtain a hydrogel precursor solution; step 4, cutting an I-shaped mold and an S-shaped mold, pouring the precursor solution in the step 3 into the mold, and obtaining conductive hydrogel under a heating condition; 5, conductive adhesive tapes or wires are arranged on the left side and the right side of the conductive hydrogel and directly extend to serve as lead wires connected with external equipment, waterproof breathable adhesive tapes are used for packaging, the I-shaped hydrogel serves as a strain sensor, the S-shaped hydrogel serves as a temperature sensor, and an IS wearable sensor is formed. According to the invention, the two modes do not interfere with each other.

The invention belongs to the technical field of compositions, and particularly relates to a traditional Chinese medicine composition with bacteriostatic, anti-inflammatory, antioxidant and whitening effects and a preparation method and application thereof. The composition provided by the invention comprises the following raw materials in parts by weight: 1-5 parts of rhodiola rosea; 5-10 parts of licorice root; and 1-5 parts of phyllanthus emblica. The composition is obtained by crushing rhodiola rosea, liquorice and phyllanthus emblica into powder raw materials and adding the powder raw materials into an extraction solvent for extraction. Compared with a composition with a single purpose, the composition disclosed by the invention has the effects of inhibiting bacteria, resisting inflammation, resisting oxidation and whitening at the same time, and the four effects of the product can be met at the same time.

The invention discloses a solid dispersion of beta-1, 3 / alpha-1, 3-glucan as well as a preparation method and application thereof, and belongs to the technical field of biology. The solid dispersion of beta-1, 3 / alpha-1, 3-glucan provided by the invention comprises beta-1, 3 / alpha-1, 3-glucan and polysaccharide, wherein the beta-1, 3 / alpha-1, 3-glucan and the polysaccharide are compounded to form the solid dispersion; the mass ratio of the beta-1, 3 / alpha-1, 3-glucan to the polysaccharide is 3: (1.5-3); the polysaccharide comprises one or more of curdlan, carrageenan and microcrystalline cellulose; the solid dispersion of beta-1, 3 / alpha-1, 3-glucan has lower viscosity and higher solubility in application, and the stability of a beverage can be effectively improved; and the preparation method is simple and easy to implement and suitable for industrial mass production, and the obtained solid dispersion does not contain a surfactant, is safer and has smaller irritation.

The invention discloses a fermented caffeine eye cream composition. Comprising the following components in parts by weight: 30 to 80 parts of a fermentation composition, 1 to 5 parts of caffeine, 0.1 to 0.3 part of hydroxypropyl tetrahydropyrantriol, 0.5 to 2 parts of nicotinamide, 0.1 to 1 part of squalane, 0.01 to 0.5 part of a ceramide composition, 0.005 to 0.05 part of dipeptide diaminobutyryl benzyl amide diacetate, 0.005 to 0.05 part of a polypeptide composition, 0.01 to 0.5 part of carnosine, 0.01 to 0.5 part of tetrahydromethylpyrimidine carboxylic acid and 3 to 12 parts of a plant extract. The invention also discloses an eye cream containing the eye cream composition. The fermented caffeine eye cream composition provided by the invention can effectively smooth the skin surface, and is beneficial to preventing and comforting aging, improving skin elasticity, improving dark circles, relieving edema and removing under-eye puffiness.

The invention discloses magnesium-based hydrogen-rich bone cement as well as a preparation method and application thereof. The magnesium-based hydrogen-rich bone cement is prepared by mixing and curing powder and curing liquid, the powder comprises the following components in parts by mass: 50-80 parts of structural powder, 10-15 parts of a bonding consumable, 5-10 parts of a healing accelerant and 15-40 parts of an auxiliary agent, the structural powder comprises reinforcing powder and compatible powder, the reinforcing powder comprises at least one of calcium silicate and calcium phosphate, and the compatible powder comprises at least one of magnesium silicate and magnesium phosphate; the healing accelerant comprises a biodegradable polymer and a magnesium-based material embedded in the biodegradable polymer; and after the powder and the curing liquid are mixed and cured, surface activation treatment is applied, and at least part of the bonded consumables are removed. The magnesium-based hydrogen-rich bone cement disclosed by the invention can be applied to preparation of bone defect repair materials, can relieve local tissue inflammatory response, and is high in oxidation resistance, long in oxidation resistance duration, few in organic residues on the ceramic surface of the bone cement and good in biocompatibility.

The invention relates to blackcurrant and orange juice assorted soda water, which belongs to the technical field of beverages, and contains blackcurrant extract, orange juice, white hyacinth bean seed extract, mogroside, stevioside and the like. Wherein the blackcurrant extract is a product which is less than 5kDa and is obtained by carrying out common enzymolysis on blackcurrants by hemicellulase and pectinase and then sequentially carrying out step-by-step enzymolysis on the blackcurrants by virtue of nattokinase, ficin, papain and glucokinase; the white hyacinth bean seed extract is a product below 5kDa obtained by performing enzymolysis on white hyacinth bean seeds through trypsin and then performing co-fermentation through propionibacterium freudenreichii, lactobacillus brevis and bifidobacterium longum; the blackcurrant extract and the white hyacinth bean seed extract have good effects of resisting fatigue, resisting oxidation and enhancing immunity, so that the assorted soda water is delicious and healthy.

The invention belongs to the technical field of biomedical materials, and particularly relates to a carboxymethyl chitin composite material for an articular cavity and a preparation method of the carboxymethyl chitin composite material. The carboxymethyl chitin composite material for the articular cavity is prepared by selecting carboxymethyl chitin, hyaluronic acid, sodium alginate and chitosan which are good in biocompatibility as raw materials and performing functional modification treatment respectively, and through the synergistic effect of all the components, the elasticity modulus of the composite material is effectively improved, the swelling rate is reduced, and the joint cavity is more stable. And meanwhile, the composite material also has proper viscosity and degradation performance, and can meet application requirements.

The present invention belongs to the field of microalgae biotechnology, and specifically relates to a chlorella SDEC-18 polysaccharide and its extraction method and application. The chlorella SDEC-18 polysaccharide of the present invention is extracted from chlorella SDEC-18, and contains 4 parts of polysaccharides with different molecular weights, and its peak molecular weights are 1030Da, 2735Da, 10.187KDa and 244.933KDa respectively; the chlorella SDEC-18 polysaccharide is composed of arabinose, galactose and talose, wherein galactose is the main component; the chlorella polysaccharide can significantly remove the excess ROS produced in the cell, reduce the MDA content, and increase the T-AOC and SOD content, and has the effect of removing free radicals and reducing oxidative stress, and has excellent antioxidant effect on the body, and has a wide range of application prospects, including for the preparation of oxidative stress products, the preparation of biopharmaceutical products, functional foods and daily chemical products that delay skin aging and improve the body's immune ability, etc.

The invention relates to the field of aromatherapy, in particular to dried flower color locking aromatherapy and a preparation method thereof. The dried flower color locking aromatherapy comprises the following components in parts by mass: a transparent glass bottle, liquid aromatherapy and dried flowers, the liquid aromatherapy is arranged in the transparent glass bottle, and the dried flowers are soaked in the liquid aromatherapy. The liquid aromatherapy product is prepared from the following components in parts by weight: 50 to 65 parts of dipropylene glycol monomethyl ether, 5 to 8 parts of benzalkonium chloride, 10 to 12 parts of deionized water and 12 to 18 parts of color locking composition, wherein the color locking composition is ethylene glycol stearate, sodium carboxymethyl cellulose and essence. According to the dried flower color locking aromatherapy, the problems of fading and corrosion of dried flowers are solved, the original color and luster of the dried flowers are kept, fading and corrosion of the dried flowers are avoided for a long time, fragrance is kept, and the dried flower color locking aromatherapy has ornamental value and decorative value.

The embodiment of the invention discloses a method for preparing a small-molecule active substance by taking aronia and medlar as raw materials. The method comprises the following steps: cleaning and crushing fresh aronia fruits and fresh Chinese wolfberry fruits to obtain slurry; protease, pectinase and cellulase are added into the pulp for an enzymolysis reaction, and an enzymolysis product is obtained; and heating the enzymolysis product to terminate enzymatic activity, purifying, and drying to obtain the micromolecular active substance. Through reasonable process design and parameter control, the purity and activity of the micromolecular active substance are effectively improved, and the prepared micromolecular active substance is more easily absorbed by a human body, has more prominent functional activity and is suitable for development of functional food and health care products.

This invention discloses an endogenous polypeptide, its preparation method, and its application. The structural formula of the polypeptide is shown in Formula (I): R1-(AA1)m-AA2-AA3-(AA4)n-R2, Formula (I); wherein, m is independently 2 or 3; n is independently 1, 2, or 3; AA1 is independently K, R, or H; AA2 is independently I or W; AA3 is independently I or W; AA4 is independently K, R, or H; R1 is any one of -H, Y, LY, PLY, or LLY; R2 is any one of -OH, L, LL, E, EL, EW, W, EH, or EHL. While retaining its targeted antioxidant and anti-inflammatory functions, the polypeptide has removed the domain with high affinity for heparin, thereby avoiding signal interference and potential biosafety risks that may be caused by full-length PF4, and meeting the safety requirements for cosmetic ingredients.

The invention provides a composition containing a marine extract, especially a coralline algae extract and deep-sea fish collagen, and a liposome containing the composition. The composition prepared by the invention is green, healthy, safe, effective and good in lasting effect, and solves the problem of skin aging of people.

The invention relates to the technical field of hemostatic cotton, in particular to rapid hemostatic cotton with good antibacterial property and adhesion as well as a preparation method and application of the rapid hemostatic cotton. The invention discloses rapid hemostatic cotton with good antibacterial property and adhesion. The rapid hemostatic cotton is obtained by sequentially carrying out carboxymethyl treatment, tannic acid treatment and silver ion chelating treatment on cotton fabric. The rapid hemostatic cotton provided by the invention has a very high liquid absorption rate, can be rapidly gelatinized when being in contact with blood, and can be adhered to a wound, seal the wound and prevent bacteria from invading the wound, so that the purposes of rapidly stopping bleeding and promoting healing are achieved.

The invention relates to the technical field of oral cavity medicines, and discloses an antioxidant polyphenol sustained-release ointment suitable for oral cavity and a preparation method and application thereof, the antioxidant polyphenol sustained-release ointment comprises the following raw materials by weight: 0.5%-5% of antioxidant polyphenol, 20%-45% of a drug solvent, 1%-10% of a water-soluble polymer substance, 15%-40% of a water-based thickener, 1%-10% of a hydrophobic polymer, and 15%-40% of an ester plasticizer. The natural polyphenol is used as a main medicine, and the natural polyphenol has multiple functions of oxidation resistance, inflammation resistance, bacterium resistance, metal ion chelation, biological adhesion and the like; the slow-release ointment is prepared from an antioxidant polyphenol substance, and a slow-release system does not contain antibiotics, has no bacterial drug resistance problem and has relatively high biological safety; the antioxidant polyphenol sustained-release ointment does not contain water, can absorb peripheral gingival crevicular fluid after being coated in a periodontal pocket, and is converted into gel with higher strength to be more stably released locally; the preparation process is simple, mild in condition and low in cost.

The invention relates to a probiotic fermentation process for increasing the content of ginsenoside, and belongs to the technical field of probiotic fermentation. The invention provides a probiotic fermentation process, which is characterized in that a compound strain is utilized, and a strain fermentation liquid is inoculated into an American ginseng liquid for fermentation culture. The compound probiotics are inoculated into the American ginseng liquid to ferment and extract the ginsenoside, the American ginseng liquid prepared through a specific process and components is rich in various beneficial components, a suitable nutrition environment is provided for growth of strains, the conversion rate and stability of the ginsenoside are improved, and then the content of the ginsenoside is increased.

The invention discloses a catalyst as well as a preparation method and application thereof, and relates to the technical field of catalysts. The catalyst comprises a metal nickel-based active component and a metal oxide deposited on the surface of the metal nickel-based active component; wherein the metal oxide comprises any one or a combination of at least two of vanadium oxide, molybdenum oxide or tungsten oxide. The catalyst has high activity and high selectivity for preparation of gamma-butyrolactone through hydrogenation reduction of maleic anhydride or succinic anhydride, the preparation process is simple to operate, the catalytic process is high in safety, the catalyst has excellent stability, the quality and quality stability of the product are improved, the process cost is reduced, the catalyst synthesis and modification cost is low, and the catalyst is suitable for industrial production. The large-scale production is facilitated.

The present application belongs to the technical field of cosmetic production, and discloses an acid-free acne-removing composition, comprising 10-20% of dipeptide-15, 1-5% of olive leaf extract, 5-10% of acetyl glucosamine, 0.1-1% of 10-hydroxydecanoic acid, 5-10% of yeast / zinc fermentation product, 1-5% of bisabolol, 5-10% of tetrahydromethylpyrimidine carboxylic acid, 1-10% of capryloyl glycine, 0.01-1% of polylysine, 28-32% of polyol and the balance of deionized water. Through the synergistic effect among the above multiple components, the antibacterial ability of the composition and the inhibitory effect on inflammatory factors 1L-1α and 5α-reductase are further improved. Moreover, the composition disclosed in the present application also has good anti-allergic ability. In addition, the present application also discloses the application of the acid-free acne-removing composition and a daily chemical product.

The invention relates to an application of violacein in preparation of a product for inhibiting or killing bacillus cereus, the violacein not only has inhibiting and killing effects on nutritional and spore bacillus cereus, but also can inhibit the formation of a bacillus cereus biofilm and remove the biofilm formed by the bacillus cereus; the bacillus cereus toxin gene expression can be inhibited, and the bacillus cereus is inhibited from generating toxin; therefore, the bacillus cereus can be used for preparing a product for preventing and removing bacillus cereus pollution, preparing a medicine for preventing and treating bacillus cereus infection and / or preparing a medicine for preventing and treating diseases caused by bacillus cereus infection.

The present invention provides a fermented product for reducing uric acid, belonging to the technical field of Chinese medicine fermentation. The fermented product fermentation raw materials include by weight: 100-180 parts of black wolfberry, 120-200 parts of eucommia male flowers, 80-160 parts of red phoenix peony flowers, 60-140 parts of ear leaf cow hide Xiao, 140-220 parts of short-stemmed acanthopanax, 60-140 parts of venous inula, 1.2-12 parts of fermented bacteria powder and 14-120 parts of enzyme preparation. The synergistic cooperation of each Chinese medicine component has a good effect of reducing uric acid under the action of enzymatic fermentation, and can also have a significant protective effect on kidney damage and liver damage, reduce serum creatinine, urine albumin excretion rate, improve glomerular filtration function; and can improve the level of inflammatory factors.

The present invention relates to the field of genetic engineering, protein engineering technology and its application, and discloses a novel recombinant collagen and its application, including any one of the recombinants COL17-CO-1, COL17-CO-2, COL17-CO-3 or COL17-CO-4 of the specific functional region of human type XVII collagen and the 1232-1466 region of human type III collagen, wherein the amino acid sequences of the specific functional regions in the COL17-CO-1, COL17-CO-2, COL17-CO-3 and COL17-CO-4 are SEQ ID No.2, SEQ ID No.6, SEQ ID No.8 and SEQ ID No.10, respectively. The recombinant exhibits better ability to promote cell proliferation, promotes the expression of proline hydroxylase (HYP), improves the antioxidant capacity of skin cells, improves the expression of multiple collagens in skin cells, and better reduces the expression of collagen degradation-related bases MMP-3 and MMP-9.