75 results about "Lithospermum" patented technology

The invention discloses a plant composition with skin anti-aging activity and a preparation thereof. The plant composition is prepared from the following active ingredients in percentage by weight: 84.0 to 89.0 percent of haematococcus pluvialis extract, 8.0 to 12.0 percent of lithospermum oil, 0.5 to 0.8 percent of melaleuca alternifolia leaf oil, 0.5 to 1.0 percent of hydrolyzed olive leaf extract, 0.1 to 0.5 percent of rhodiola rosea root extract and 1.2 to 2.5 percent of bitter orange leaf oil. The plant composition with the skin anti-aging activity is used as an effective component, other auxiliaries are added, and emulsion, cream or essence oil is prepared. According to the plant composition and the preparation, the fermented camelina seed oil, the fermented safflower seed oil, the fermented meadowfoam seed oil and the like are used as solvents for extracting active components in haematococcus pluvialis and are also used as functional components and matrixes of the preparation, and compared with application of original plant oil, the plant composition and the preparation have better skin feeling and biological activity; the extraction rate of active ingredients in haematococcus pluvialis is higher, and transdermal absorption of the active ingredients is facilitated.

The invention belongs to the field of medicines, and relates to a compound derived from Sinkiang lithospermum, a preparation method thereof and application of the compound in prevention and treatment of cardiovascular diseases. Specifically, the invention discloses a monoterpene benzoquinone derivative with a novel structure in Sinkiang lithospermum, a preparation method of the monoterpene benzoquinone derivative and application of the compound in preparation of anti-myocardial injury drugs. An in-vitro anti-myocardial cell injury activity experiment proves that the compound has a remarkable protection effect on isoprenaline (ISO)-induced H9C2 cell (rat embryo myocardial cell) injury and hypoxia-reoxygenation-induced H9C2 myocardial cell injury. The result shows that the compound can be used for preparing the anti-cardiovascular disease medicine.

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for relieving pain, promoting blood circulation, diminishing swelling and removing blood stasis, application thereof and a blood stasis dispersing and pain relieving patch. The invention provides a traditional Chinese medicine composition for relieving pain, activating blood, diminishing swelling and removing stasis. The traditional Chinese medicine composition comprises the following components: lycopodium clavatum, radix clematidis, asarum, gentiana macrophylla, radix angelicae, rheum officinale, notopterygium root, roasted herba epimedii, radix achyranthis bidentatae, peach kernel, radix angelicae pubescentis, vinegar-processed rhizoma corydalis, vinegar-processed rhizoma cyperi, moutan bark, prepared kusnezoff monkshood root, prepared monkshood, vinegar-processed frankincense, Sinkiang lithospermum, vinegar-processed myrrh and sanguisorba officinalis. The blood stasis dispersing and pain relieving patch has the advantages of being good in curative effect, quick in effect taking, convenient to use, safe and reliable, can be used for treating traumatic injuries and pain caused by cervical spondylosis, scapulohumeral periarthritis, lumbar disc herniation, lumbar vertebrae hyperosteogeny, spinal stenosis, sciatica, ankylosing spondylitis, arthritis and other diseases, and can achieve the effect of treating both symptoms and root causes.

The invention relates to the technical field of antibiosis, and discloses a traditional Chinese medicinal material antibacterial component compounding method with a nano-particle self-assembly behavior, which comprises the following steps: S1, a traditional Chinese medicinal material component extraction framework step for extracting an antibacterial component extract from lithospermum erythrorhizon and moutan bark medicinal materials; s2, a step of preparing a nano-particle carrier framework, wherein the nano-particle carrier framework is used for constructing a nano-carrier system composed of chitosan and sodium hyaluronate; s3, an antibacterial component compounding frame step: carrying out self-assembly compounding on the antibacterial component extract and the nano-particle carrier to generate antibacterial nano-composite particles; and S4, a composite particle drying frame step: treating the composite particles through centrifugation and freeze drying to obtain the antibacterial nano composite powder. The long-time sustained release of the antibacterial effect is realized by encapsulating the antibacterial component through the nano composite carrier, optimizing the particle size and adopting a sustained release technology, the stability and bioavailability of the medicine are improved, and side effects caused by excessive release of the medicine are avoided.

The invention discloses ointment for preventing infantile hand-foot-and-mouth disease and a preparation method thereof. The ointment is prepared from coptis chinensis, sweet wormwood, honeysuckle, radix sophorae flavescentis, lithospermum, sanguisorba officinalis, radix isatidis, menthol, clove oil, vitamin A oil, vitamin E oil, roxburgh rose seed oil, olive oil, chamomile extract, honey and microcrystalline wax. On the basis of combination of traditional Chinese medicines and western medicines, traditional Chinese medicine components such as coptis chinensis, artemisia apiacea and honeysuckle and western medicine components such as vitamin A and vitamin E are combined, and the ointment for preventing the infantile hand-foot-and-mouth disease is prepared. The components have the effects of clearing away heat and toxic materials, resisting viruses, bacteria and inflammation and the like, and are beneficial to enhancing the immunity of the organism, inhibiting virus diffusion and relieving disease symptoms, so that the occurrence of the infantile hand-foot-and-mouth disease is effectively prevented.

The invention belongs to the technical field of traditional Chinese medicines, and provides a badger fat compound external preparation for treating radioactive skin injury. According to the traditional Chinese medicine differentiation of radioactive skin injury, the compound preparation is prepared by selecting a method of clearing away heat and toxic materials, eliminating dampness, promoting blood circulation, removing blood stasis, removing slough, promoting granulation, cooling blood and nourishing yin, and comprises the following main components: raw rhubarb, lithospermum, sanguisorba officinalis, aloe, folium isatidis, cottonrose hibiscus leaves, dandelion, badger fat and borneol. The compound preparation is prepared from Chinese herbal medicines and badger fat according to unique pathological characteristics of radioactive skin injury, and has a better treatment effect on radioactive skin injury, especially moderate and severe injury.

The invention discloses a traditional Chinese medicine composition for treating verruca plana and a preparation method and application thereof, and the traditional Chinese medicine composition for treating verruca plana comprises the following components in parts by weight: 48-72 parts of isatis root, 48-72 parts of coix seed, 48-72 parts of purslane, 24-36 parts of lithospermum, 16-24 parts of peach kernel, 16-24 parts of safflower, 48-72 parts of horsetail, 16-24 parts of rhizoma cyperi, 48-72 parts of nacre mother of pearl, 16-24 parts of honeycomb and 48-72 parts of raw oyster. The nacre mother and the nidus vespae with high dosage are combined with the raw oysters, so that double enhancement of hardness softening, stagnation eliminating, toxic material counteracting and virus resisting is realized, the combination of the nacre mother and the nidus vespae is not seen in the prior art, and the cure rate can be remarkably increased and the recurrence rate can be remarkably reduced.

The present invention discloses a traditional Chinese medicine composition for treating arthralgia syndrome, which comprises the following raw materials in parts by weight: 15-25 parts of lithospermum root, 15-25 parts of limnophila aromatica (Lam.) Merr., 12-18 parts of dragon's blood, 12-18 parts of cortex phellodendri, 12-18 parts of rheum officinale, 12-18 parts of ardisia gigantifolia stapf, 9-15 parts of coptis chinensis, 6-10 parts of frankincense, 6-10 parts of myrrh, 12-18 parts of menthol, 12-18 parts of borneol, 8-12 parts of cinnabar, and 45-60 parts of rehmannia glutinosa. The present invention also discloses a preparation method of the traditional Chinese medicine composition for treating arthralgia syndrome. The present invention has the effects of clearing heat and detoxifying, cooling blood and nourishing yin, promoting blood circulation to remove blood stasis, relieving pain and calming the mind, dispelling wind and removing dampness, can effectively relieve the discomfort of patients, and will not damage the body fluid of the human body during the heat-clearing process, nor will it damage the healthy qi during the blood stasis-removing process, truly achieving the effect of dispelling pathogenic factors and strengthening healthy qi.

The application discloses a kind of treatment granulomatous lobular mastitis plaster and preparation method thereof, it is related to traditional Chinese medicine technical field, and its technical solution points are: rhubarb, golden poplar, radix scutellariae, sanguisorba officinalis, gardenia, turmeric, purple grass, water decoct 2 times, first time 9-11 times water amount of medicinal materials is added, decoct 1-3 hours, second time 6-9 times water amount of medicinal materials is added, decoct 1-2 hours, two water decocting liquids are combined, after filtration, concentrate and obtain ointment, carry out coating, cut according to specification and place to make it solidification and shape.The application can realize the treatment granulomatous lobular mastitis, can reduce mastitis inflammation index score and inflammatory cell infiltration degree, by reducing the expression of IL6, CD86, TYROBP, ITGAX and regulating related path, play the role of treatment granulomatous lobular mastitis.

The application discloses a kind of clean face acne traditional Chinese medicine composition and application and gel containing the composition, it is related to clean face acne product technical field.The clean face acne traditional Chinese medicine composition of the application, including the following weight parts of raw material composition: 5-60 parts of forsythia suspensa extract, 3-50 parts of rhubarb extract, 2-50 parts of sophora flavescens extract, 5-60 parts of radix lithospermi extract, 1-25 parts of sparganium extract, 5-60 parts of herba violae extract, 3-50 parts of scutellaria baicalensis georgi extract, 2-50 parts of herba taraxaci extract, 2-50 parts of red root of tree peony extract, 1-25 parts of bletilla striata extract, 1-25 parts of mentha haplocalyx extract;Meanwhile, the gel containing the composition is disclosed.The application effectively realizes bacteriostasis for traditional Chinese medicine preparation, reduces skin inflammatory response, shortens acne subsidence time;Regulate sebaceous secretion, improve skin metabolism, accelerate the subsidence of acne;Redness average value before and after use and acne volume contrast is remarkable, and curative effect is exact.

The invention belongs to the technical field of skin wound repair, and particularly relates to application of a compound in preparation of a scar relieving agent and an external scar removing agent. According to anti-scar traditional Chinese medicine prescription analysis and component and activity research, daucosterol, shikonin, przewalskin C and 4-ethoxyformyl-quinol-2-ketone have the effects of inhibiting proliferation of human keloid fibroblasts and inhibiting collagen synthesis of human normal skin fibroblasts induced by TGF-beta1; the composition has a scar relieving effect on scars of scar animal models, and can be used as a scar relieving agent, especially an external preparation applied to local skin. The invention further discloses an external scar-removing agent, namely an emulsion-type liniment, the main component of the external scar-removing agent contains silicone oil and also contains any one of an antioxidant and / or daucosterol, shikonin, przewalskin C and 4-ethoxyformyl-quinoline-2-ketone, and the main component has a better effect of relieving scars of a scar animal model when being externally applied to local skin.

The invention discloses an external ointment for rhinitis, a preparation method and application, which can effectively treat chronic rhinitis with nasal obstruction, sneezing and dry nose as main symptoms, and the ointment is non-invasive, convenient and non-irritant to skin. The external ointment for rhinitis comprises the following raw materials in percentage by mass: 5% of ephedra, 5% of almond, 5% of cocklebur fruit, 5% of wine-processed scutellaria baicalensis, 5% of radix angelicae, 5% of moutan bark, 5% of lithospermum, 5% of magnolia flower, 5% of selaginella tamariscina, 2.5% of borneol, 45% of sesame oil and 7.5% of beewax.

The invention discloses a group of traditional Chinese medicine blusher and a preparation process thereof. The invention belongs to the field of cosmetics, and particularly relates to a group of traditional Chinese medicine blusher and a preparation process thereof. The invention provides a composition for brightening skin color. The composition comprises a traditional Chinese medicine extract composition, a matrix and dry powder, the traditional Chinese medicine extract composition contains a lithospermum extract, a salvia extract and a rose extract. Wherein the mass ratio of the radix arnebiae seu lithospermi extract to the radix salviae miltiorrhizae extract to the rose extract is (4-8): 1: 1. According to the blusher with the traditional Chinese medicine extract as the color source and the preparation technology of the blusher, natural medicinal materials such as radix arnebiae seu lithospermi, radix salviae miltiorrhizae and roses serve as core raw materials, related components are extracted through the technology combining hot dipping and cold dipping, the natural and healthy characteristics of traditional Chinese medicine are creatively combined with the function of cosmetics, and the blusher has application prospects.

The invention provides a traditional Chinese medicine composition for preventing hair loss and promoting hair growth and application thereof, and relates to the technical field of hair loss prevention and promoting hair growth, the traditional Chinese medicine composition is composed of Chinese doughnut, cockscomb, albizia flower, Chinese honey locust, schizonepeta, lithospermum, polygonum multiflorum, prepared rehmannia root, notopterygium root, radix angelicae pubescentis, ruddle and periostracum cicada; in-vitro experiments show that the traditional Chinese medicine composition can promote proliferation of human dermal papilla cells HDPC, relieve the damage degree of HDPC and induce cycle transformation of hair follicles, so that the effect of promoting hair growth is achieved; animal experiments show that the traditional Chinese medicine composition can significantly increase the number of hair follicles and the thickness of skin and dermis fat of mice, reduce the levels of mouse serum IL-2, TNF-alpha and TGF-beta1 and reduce the levels of testosterone, dihydrotestosterone and estradiol in mouse skin tissue, so that hair follicle fibrosis is inhibited, the growth period of hair follicles is accelerated, the growth period is prolonged, the hair loss phenomenon is improved, and the hair loss rate is increased. The hair growth is promoted.

The invention discloses a traditional Chinese medicine composition for treating chronic prostatitis and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following components in parts by weight: 15-35 parts of polygonum capitatum, 15-30 parts of polygonum cuspidatum, 15-35 parts of rhizoma smilacis glabrae, 10-30 parts of plantain herb, 5-20 parts of fructus kochiae, 5-20 parts of winged euonymus twig, 5-20 parts of turtle shell, 1-5 parts of leech, 5-20 parts of lithospermum, 5-20 parts of artemisia anomala, 5-20 parts of loofah sponge, 5-20 parts of fructus aurantii, 5-20 parts of Chinese waxgourd seed, 5-20 parts of geranium wilfordii, 5-20 parts of chinaroot greenbrier and 5-20 parts of herba epimedii. , 5-20 parts of cowherb seed and 1-10 parts of amber. The traditional Chinese medicine composition has a good treatment effect on chronic prostatitis caused by damp-heat stasis and can effectively solve the problems of existing western medicines.

The invention belongs to the technical field of herbaceous plant extraction, and particularly relates to a collateral-dredging health-care gel extracted from herbaceous plants and a preparation process of the collateral-dredging health-care gel. The herbaceous plant raw materials are specifically prepared from coptis chinensis, radix sophorae flavescentis, pseudo-ginseng, dragon's blood, radix angelicae, lithospermum erythrorhizon, herba violae, fructus cnidii, cortex dictamni, fructus kochiae, angelica sinensis, turmeric, rhodiola rosea, selfheal, radix ranunculi ternati, pepper, rhizoma atractylodis, chamomile, smoked plum, saussurea involucrata, liquorice and water; the matrix is specifically prepared from carbomer, propylene glycol, glycerol, triethanolamine, nicotinamide, sodium polyglutamate, phenoxyethanol, fibronectin, sodium hyaluronate and purified water. Through combination of various herbaceous plant extracts and modern skin care components, the traditional Chinese medicine composition aims to regulate qi and blood in the body and promote blood circulation in an external use manner, and has a remarkable health care effect. The preparation process is scientific and reasonable, the curative effect of herbaceous plants is fully exerted, and meanwhile, the stability and safety of the product are ensured.

The invention relates to a saffron crocus eye pad and a method for controlling eye axis growth, and belongs to the technical field of eye care products. The eye patch comprises a patch carrier and a plant extraction gel layer coated on the patch carrier, the plant extract gel layer is composed of mulberry leaf extract, chrysanthemum extract, butterflybush flower extract, amur corktree extract, crocus sativus flower extract, lithospermum extract, madder extract, lycium ruthenicum extract, beet root juice powder, natural borneol, menthol, xanthan gum, purified water and other natural components. The crocus sativus flower extract can enhance the blood flow speed of choroid, thicken the choroid and effectively control the growth of an ocular axis, so that the effect of delaying or improving the development of myopia is achieved. According to the gel layer, a hydrogel structure is formed through xanthan gum, natural borneol and menthol are combined to provide cooling and soothing effects, and the gel layer has good skin affinity and use safety.

The present application relates to traditional Chinese medicine composition and its application in the field of skin inflammation diseases, and discloses a kind of drug composition for treating skin inflammation and its preparation method and application.The composition is prepared from white fungus, tribulus terrestris, smilax glabra, kochia scoparia, honeysuckle, baishiy, rehmannia glutinosa, oak, peony, radix lithospermi, periostracum cicadae, licorice, gardenia and sophora flavescens.The UPLC-Q-TOF-MS identification contains 110 kinds of components;Animal experiments show that it can significantly reduce psoriasis skin lesions, down-regulate TNF-alpha, IL-1beta and IL-6, up-regulate IL-10, and inhibit PI3K-Akt pathway.The present application has clear components, clear mechanism and definite curative effect, and can be used for preparing medicine for treating psoriasis, chronic urticaria and senile pruritus.

The invention discloses a traditional Chinese medicine formula and application of the traditional Chinese medicine formula in preparation of nanoscale external medicine for treating light and moderate burns and scalds. The traditional Chinese medicine formula comprises the following raw material medicines in parts by mass: 6 parts of polygonum cuspidatum, 4 parts of scutellaria baicalensis, 4 parts of coptis chinensis, 3 parts of golden cypress, 4 parts of raw rhubarb, 3 parts of sanguisorba officinalis, 4 parts of gardenia, 4 parts of lithospermum, 2 parts of borneol and 200 parts of sesame oil. The external medicine for treating light and moderate burns and scalds, prepared by adopting the prescription, is low in cost, has a broad-spectrum bacteriostatic effect, takes effect quickly and can achieve an obvious pain relieving effect within 30 minutes after being used, and burns and scalds are basically healed after being used for 7-14 days; the safety is high, and accidental adverse reactions can be automatically relieved; the ointment is suitable for mild to moderate burns and scalds, skin heat toxin red and swollen, eczema fester, sore and ulcer swelling and the like.

The application discloses a kind of traditional Chinese medicine for treating eczema, mainly by first composition and second composition are made, the raw materials of the first composition include: smilax glabra, gangban gui, Chinese potentilla, triaenophora, atractylodes, wind-preventing plant;The raw materials of the second composition include: cortex phellodendri, honeysuckle stem, Chinese alpine, prunus mume, silver radix scophulariae, schisandra chinensis, ramulus mori, portulaca oleracea, licorice, astragalus, capillaria herba.The traditional Chinese medicine for treating eczema of the application, heat-clearing and detoxifying, expelling wind and removing dampness, can better improve the TCM syndrome score, EASI score, the degree of pruritus score, dermatology life quality index (DLQI) score of eczema patient, effectively improve the clinical problems of eczema patient, improve the quality of life.

The invention provides antibacterial hydrogel loaded with lithospermum carbon dots as well as a preparation method and application of the antibacterial hydrogel. The lithospermum carbon dots are prepared from lithospermum through a hydrothermal method; the carboxymethyl chitosan, the 4-aldehyde phenylboronic acid and the ellagic acid are cross-linked through a Schiff base bond and a phenylboronic acid ester bond to obtain the CM hydrogel. The hydrogel LE-CDs (at) CM loaded with the Chinese herbal medicine carbon dots is prepared by blending carboxymethyl chitosan, 4-formylphenylboronic acid, ellagic acid and lithospermum carbon dots, and the hydrogel has good water retention property, adhesion, biocompatibility and antibacterial property, is an ideal biological material, and provides a new thought for development of hydrogel wound dressing.

The present invention provides a traditional Chinese medicine ointment for treating hand-foot syndrome and a preparation method thereof. The ointment is made from the following ingredients: sesame oil, lithospermum erythrorhizon, angelica dahurica, bletilla striata, white mulberry, angelica sinensis, rhubarb, knotweed, honeysuckle, siler, raw rehmannia root, pearl powder, dragon's blood, borneol, radix trichosanthis, frankincense, myrrh, rosin, lard, beeswax, and quicklime. This ointment enhances the original Ziyun ointment by adding bletilla striata, rhubarb, knotweed, honeysuckle, pearl powder, dragon's blood, borneol, radix trichosanthis, frankincense, myrrh, and other ingredients, thereby enhancing its yin-nourishing, blood-cooling, and detoxifying effects. The ointment exhibits excellent effects in alleviating pain, removing rotten flesh, stopping bleeding, promoting tissue regeneration, and providing antibacterial and anti-inflammatory benefits, as well as promoting wound healing. The developed Yufu Jiedu ointment has demonstrated excellent initial efficacy in the clinical treatment of capecitabine-induced hand-foot syndrome, receiving unanimous praise from patients and addressing the shortcomings of the existing technology.

The invention discloses a natural plant acne-removing composition with high stability. The natural plant acne-removing composition is prepared from the following components in parts by weight: 20 to 40 parts of herba verbenae extract, 30 to 60 parts of spiraea ulmus extract, 10 to 20 parts of linear aspartame extract, 1 to 3 parts of radix arnebiae seu lithospermi extract and 2 to 4 parts of tetrahydropiperine. The radix arnebiae seu lithospermi extract is wrapped by a phospholipid-cyclodextrin composite carrier, fat-soluble shikonin is converted into a water-soluble and high-stability core-shell structure, the composition can form a three-dimensional synergistic system of bacteriostasis, oil control and anti-inflammatory repair, the effect of improving light and moderate acne is remarkable, and recurrence can be effectively prevented.

The invention discloses a traditional Chinese medicine composition, itching-relieving repair gel and a preparation method and application thereof, the traditional Chinese medicine composition is composed of lithospermum extract, centella asiatica extract, fructus kochiae extract and water chestnut hull extract, so that the traditional Chinese medicine composition is a natural Chinese herbal medicine substance and has the characteristics of being mild and non-irritating; the itching-relieving repairing gel prepared by the preparation method disclosed by the invention has the advantages of mild components, safety, no irritation and good repairing and itching-relieving effects, and the skin wound healing is promoted while the effects of resisting bacteria and relieving itching are exerted, and the obtained itching-relieving repairing gel product has the advantages of mild components, safety, no irritation and good repairing and itching-relieving effects.

The invention provides a traditional Chinese medicine compound capable of inhibiting bacteria, tightening and promoting vaginal repair as well as a preparation method and a preparation of the traditional Chinese medicine compound. The preparation method comprises the following steps: performing supercritical CO2 extraction on radix arnebiae seu lithospermi and saffron crocus to obtain radix arnebiae seu lithospermi-saffron crocus extract liquor; performing dynamic countercurrent extraction on the chrysanthemum and vitex agnus-castus powder, filtering, and collecting filtrate; adding pollen typhae powder into the filtrate, performing ultrasonic-assisted extraction, filtering, and collecting a composite extracting solution; mixing cortex phellodendri, radix sophorae flavescentis, radix angelicae sinensis and herba euphorbiae tripsaci after being soaked in the yellow wine, adding water, inoculating a composite strain which is composed of lactobacillus plantarum and bacillus subtilis subspecies, fermenting and filtering to obtain fermentation liquor; after sterilization, the traditional Chinese medicine compound is prepared from the radix arnebiae seu lithospermi-pollen typhae-saffron crocus extracting solution and the compound extracting solution. The composite traditional Chinese medicine liquid prepared from the traditional Chinese medicine compound can obviously improve the vaginal health index and obviously improve the vaginal relaxation degree at the same time. And the antibacterial agent has a good antibacterial effect on candida albicans and staphylococcus aureus.

The invention relates to the technical field of traditional Chinese medicines, and discloses an external Chinese herbal medicine formula for inhibiting ocular axis growth and a preparation method. The formula comprises the following components in parts by mass: 2 to 5 parts of bat dung, 15 to 25 parts of senecio scandens, 5 to 8 parts of safflower, 6 to 10 parts of snow lotus herb, 5 to 9 parts of Chinese starjasmine stem, 8 to 12 parts of scutellaria baicalensis, 8 to 12 parts of coptis chinensis, 8 to 12 parts of golden cypress, 15 to 25 parts of wild chrysanthemum flower, 6 to 10 parts of mint, 1 to 2 parts of borneol, 25 to 35 parts of calamine, 8 to 12 parts of compound of glauber-salt and liquorice, 1 to 3 parts of storax, 4 to 6 parts of lithospermum, 4 to 6 parts of cassia seed, 6 to 10 parts of butterflybush flower, 5 to 8 parts of pearl liquid and honey. The gel is prepared from the following components in parts by weight: 1-6 parts of a silk fibroin-alginic acid dynamic gel matrix, 8-12 parts of butterflybush flower nanocrystals, 4-6 parts of magnet-indigo naturalis composite particles and 70-80 parts of the silk fibroin-alginic acid dynamic gel matrix. Targeted delivery, magnetically controlled slow release and dynamic gel technologies are fused, and accurate delivery, long-acting stable release and controllable irritation of active ingredients are realized.

The invention provides a method for assisting MALDI-MS (Matrix Assisted Laser Desorption / Ionization Mass Spectrometry) to analyze small molecular compounds in positive and negative ion modes by taking zinc sulfide as a substrate and loading a composite nano material (ZnS at Au) of gold nanoparticles as a matrix. The optimized ZnS (at) Au material can realize high-sensitivity comprehensive analysis of bioactive small molecules in traditional Chinese medicinal materials, and panoramic research is carried out on the reprogramming effect of the ZnS (at) Au material and tumor cell metabolism. Through comprehensive analysis of small molecule fingerprints of 11 Chinese herbal medicine extracts (including ailanthus altissima, walnuts, rheum officinale, madder, polygonum multiflorum, polygonum cuspidatum, semen cassiae, folium sennae, aloe, salvia miltiorrhiza and lithospermum) containing anthraquinone substances in a positive and negative double-ion mode, totally 12 types and 50 types of small molecule compounds are preliminarily identified; the method can provide powerful technical support for traditional Chinese medicine active ingredient research and new medicine development.

The application provides a traditional Chinese medicine gel for treating stubborn skin color spots and a preparation method thereof, and the traditional Chinese medicine gel is prepared from the following raw materials in mass parts: aloe extract 25-30 parts, opuntia dillenii Haw extract 10-15 parts, safflower 5-10 parts, radix lithospermi 5-8 parts, herba portulacae 5-8 parts, purified water 60-65 parts, carbomer 1-5 parts, fish scale glue 5-8 parts, hydrogenated castor oil 100-110 parts, ethanol 120-140 parts and monoglyceride 4-10 parts. The prepared traditional Chinese medicine gel can clear heat and cool blood, remove blood stasis and remove spots, promote skin metabolism, repair damaged skin cells, and can treat stubborn skin color spots such as chloasma, melasma and age spots, and has no side effects.

The invention relates to the technical field of traditional Chinese medicine compositions, and discloses a traditional Chinese medicine composition for treating stress injury, a preparation method and foam excipients, the traditional Chinese medicine composition for treating stress injury comprises the following raw materials by weight: 4-10 parts of safflower, 15-20 parts of Chinese angelica, 13-17 parts of Radix Astragali, 3-5 parts of borneol, 3-7 parts of Rhizoma Bletillae, 2-6 parts of lithospermum and 12-14 parts of red peony root. The traditional Chinese medicine composition can remarkably shorten the healing time of the first-stage stress injury and reduce the morbidity of high-risk groups.

The invention provides lithospermum oil and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The lithospermum oil comprises lithospermum, cortex phellodendri, sanguisorba officinalis, radix angelicae, frankincense, myrrh, liquorice and tea oil, wherein the tea oil comprises cold-pressed tea oil and hot-pressed tea oil. The effect of the cold-pressed tea oil is enhanced by fermenting tea seed kernel meal through compound microorganisms (lactobacillus acidophilus MY2 and bifidobacterium lactis A13); the eutecticevaporate solvent is adopted to perform ultrasonic extraction on the active ingredients in the lithospermum, so that the anti-inflammatory ingredients in the lithospermum can be efficiently extracted and retained. The lithospermum oil has the effects of clearing away heat and toxic materials, cooling and activating blood, relieving swelling and pain, removing necrotic tissue and promoting granulation. Animal experiments show that the lithospermum oil can remarkably inhibit mouse ear swelling, reduce the serum inflammatory factor level and promote healing of scalded wounds, and the effect of the lithospermum oil is superior to that of commercially available control products. The lithospermum oil prepared by the invention has anti-inflammatory and repairing dual effects, and is suitable for treating skin / soft tissue injuries such as diaper dermatitis, burns and scalds, fractured tendon injury blisters and the like.