128 results about "Leukoplakia" patented technology

Devices and methods are provided for ablating areas of the gastrointestinal tract affected with certain benign, pre-cancerous, or early cancerous lesions that originate within the epithelium and are limited to the mucosal layer of the gastrointestinal tract wall. Examples of such lesions include benign conditions such as cervical inlet patch (ectopic gastric mucosa in the upper esophagus), as well as pre-cancerous and cancerous conditions such as intestinal metaplasia/intra-epithelial neoplasia/early cancer of the stomach, squamous intra-epithelial neoplasia and early cancer of the esophagus, oral and pharyngeal leukoplakia, flat colonic polyps, anal intra-epithelial neoplasia (AIN), and early cancers of the anal canal. Ablation, as provided the invention, commences at the epithelial layer of the gastrointestinal wall and penetrates deeper into the gastrointestinal wall in a controlled manner to achieve a successful patient outcome, the latter of which is defined generally as eradication of the targeted lesion, and/or a change in the targeted lesion to prevent or forestall patient morbidity. Embodiments of the device include an ablational electrode array that spans 360 degrees and an array that spans an arc of less than 360 degrees.

A lubricant for preventing and treating the vaginal xerosis, pruritus vulvae and leukoplakia vulvae is prepared from polymycose, hyaluronic acid and medicinal auxiliaries.

A compound Chinese herbal medicament preparation for preventing and treating white spot syndrome is prepared by following raw materials by weight: 20-35 parts of Corydalis bungeana Turcz., 25-40 partsof radix isatidis, 15-40 parts of radix astragali, 20-40 parts of dyers woad leaf, 25-35 parts of wrinkled giant hyssop, 10-30 parts of Japanese eupatorium, 15-25 parts of roughhaired holly root and5-15 parts of Gynostemma pentaphylla. The compound Chinese herbal medicament preparation can effectively prevent and treat the white spot syndrome. The invention also discloses a forage comprising thecompound Chinese herbal medicament preparation and a method for feeding the same. The forage comprising the compound Chinese herbal medicament has simple processing technology and convenient feeding.The method for feeding the forage comprising the compound Chinese herbal medicament is scientific and reasonable and has a good antiviral effect.

The invention relates to the technical field of image segmentation, and discloses a construction method of an image segmentation model, and an image segmentation method and system, and the method comprises the steps: collecting a plurality of oral medical images, and obtaining an oral medical image sample set; labeling the leukoplakia area of the oral medical image to obtain a leukoplakia area labeling sample set of the oral medical image; inputting the oral medical image leukoplakia region labeling sample set into a Mask R-CNN-S neural network to obtain a binary mask image set of leukoplakiaregions; training a pre-constructed Mask R-CNN-S neural network model, so as to obtain a trained Mask R-CNN-S neural network model; collecting a to-be-segmented oral medical image and labeling the to-be-segmented oral medical image to obtain a labeled sample set of the to-be-segmented oral medical image; and segmenting the oral medical image to finally obtain a segmented image. According to the invention, the accuracy of segmenting the leukoplakia area from the oral medical image can be improved.

The present invention relates to a system and method for the photomodulation of living tissue. When photomodulated, living tissue will exhibit bioactivation or bioinhibition according to the present invention and, when using the disclosed sources of narrowband multichromatic radiation can cause significant dermatologic advantages such as hair removal, hair growth stimulation, wrinkle reduction, acne reduction and scar removal, vitiligo, etc. The present invention has application to non-dermatological medical treatments including tumor growth inhibition, cell regeneration, the stimulation of tissue in organs, etc.

The invention discloses an external traditional Chinese medicine composition for treating leukoplakia vulvae. The crude medicine is characterized by comprising the following components according to weight ratio: 6 g of polygonum cuspidatum, 12 g of red flower, 10 g of lithospermum, 9 g of golden cypress, 10 g of radix sophorae flavescentis, 30 g of garden balsam stem and 3 g of borneol; the preparation method comprises the following steps: soaking, brewing and filtering the medicines in cool water according to weight ratio so as to obtain liquid medicine, which is the xternal traditional Chinese medicine for treating leukoplakia vulvae. The traditional Chinese medicine provided by the invention is easily obtained and is low in cost; the medicines are matched reasonably to achieve synergistic effect, so the composition can achieve the purposes of promoting blood circulation and removing blood stasis, fighting bacterium diminishing inflammation, relieving itching, promoting diuresis and expelling the wind, clearing heat and detoxicating, stopping pain and dispersing swelling, enhancing skin blood circulation and promoting subcutaneous elasticity. The medicine composition has the advantages of no allergy, safety in use, strong pertinence, good effect, high cure rate and the like.

The invention discloses a traditional Chinese medicine preparation for treating vitiligo, which is prepared from the following raw materials according to weight portions: 18 portions to 30 portions ofpolygonum multiflorum, 9 portions to 30 portions of tribulus terrestris, 10 portions to 18 portions of Chinese angelica, 10 portions to 15 portions of red paeony root, 6 portions to 10 portions of safflower, 10 portions to 18 portions of suberect spatholobus stem, 6 portions to 12 portions of radix angelicae, 10 portions to 30 portions of black sesame seed, 5 portions to 10 portions of semen psoraleae and 10 portions to 30 portions of black bean peal. The preparation method comprises following steps: mixing all the raw materials together and decocting conventionally to obtain decoction, i.e.,the traditional Chinese medicine preparation. The specific operation comprises the following steps: placing all the raw materials in a container, adding water, immersing the raw materials, decoctingfor 20 minutes to 3 hours, tilting or filtering the decoction and obtaining the traditional Chinese medicine preparation. The traditional Chinese medicine preparation has the main functions of nourishing and activating the blood, nourishing liver and kidney, dispelling wind and meridians and eliminating leukoplakia, and mainly treats vitiligo.

The invention relates to an antibacterial lotion for treating leukoplakia of vulva and intractable pruritus of vulva and a preparation method thereof, and the formula of the antibacterial lotion comprises the following active ingredients in parts by weight: 14-16 parts of common cnidium fruit, 9-11 parts of lightyellow sophora root, 9-11 parts of Chinese pulsatilla root, 9-11 parts of sessile stemona root, 9-11 parts of densefruit pittany root-bark, 11-13 parts of belvedere fruit, 3-5 parts of pricklyash peel, 9-11 parts of glabrous greenbrier rhizome, 7-9 parts of swordlike atractylodes rhizome, 9-11 parts of malaytea scurfpea fruit, 7-9 parts of amur corktree bark, 4-6 parts of sulfur and 2-4 parts of borneol. When in preparation, the borneol and the sulfur are ground; then the common cnidium fruit, the lightyellow sophora root, the Chinese pulsatilla root, the sessile stemona root, the belvedere fruit, the pricklyash peel, the glabrous greenbrier rhizome, the swordlike atractylodes rhizome, the densefruit pittany root-bark and the amur corktree bark are mixed and crushed, pass through a 40-mesh sieve, then are uniformly mixed with the borneol and the sulfur according to the equal increment way and are further packaged; and irradiation sterilization at the temperature of 60 DEG C is carried out, thus the antibacterial lotion is obtained. The antibacterial lotion is simple to use, has no taboos, no pains and no side effects to a human body, and have no adverse effects on other treatment medicaments.

The present invention relates to a pharmaceutical composition for cell therapy of pigmentation disorders, which comprises as an active ingredient (a) melanocytes and keratinocytes, or (b) melanocytes and fibroblasts. The cell therapy composition of this invention allows for the first time to treat pigmentation disorders through cell therapy regimen. The present composition comprises as active ingredients a mixed cell preparation of melanocytes and keratinocytes or a mixed cell preparation of melanocytes and fibroblasts such that it induces very effectively pigmentation to treat diseases associated with hypopig mentation such as vitiligo.

The invention discloses an oral biological agent for preventing and curing prawn leukopathia. The agent has the following components in percentage by weight: 1-10% of reformed Bacillus subtilis expressing VP28, 5-50% of chitosan and balance of corn starch used as a carrier. The agent has safe use, and can effectively prevent and cure prawn leukopathia syndromes.

The invention relates to a biological dressing for eliminating white spots and scars on human body, and belongs to the technical field of medical articles. The dressing is mainly composed of the following components in percentage by weight: 0.9 to 3.0% of procyanidine, 6 to 12% of scallion extract, 4 to 9% of fleece-flower root extract, 2 to 6% of psoralen, 0.6 to 1.0% of emulsifier, 0.4 to 1.0% of skin penetrating agent, and the balance being water. The preparation method of the biological dressing comprises the following steps: weighing oil-phase raw materials according to the formula, heating, filtering so as to obtain first emulsion; individually weighing water-phase raw materials, heating; adding first emulsion, stirring, adding an emulsifier, stirring under three stirring speeds, allowing the system to stand still for 11 to 12 hours; cooling, detecting, filling, packaging, coding, and finally storing in a warehouse. The provided biological dressing can eliminate white spots, is capable of eliminating the scars and relieving itch, and does not have any side or toxic effect.

The ointment for treating leukoplakia vulvae is prepared with medicine material, oil phase supplementary material and water phase supplementary material. The medicine material includes red sage, dittany bark, mint, borneol, vitamin AD, vitamin E, vitamin B2, metronidazole disodium phosphate, urea, dexamethasone and sexual hornmone. The oil phase supplementary material consists of stearic acid, Vaseline, Nipagin and glyceryl monostearte; and water phase supplementary material consists of glycerin, triethanolamine and lauryl sdsulfate. The ointment has total clinical effective rate up to 98%.

The invention relates to an oral preparation for treating vitiligo, the preparation is prepared by the ana roots, cloves, dried ginger, aniseed, nigella seed, vegetable seedsf, west fruit, acid vine fruit, deworming Vernonia, psoralen, yellow myrobalan skin, belleric terminalia fruit, emblic leafflower fruit, and saffron. The clinical data indicate that 286 cases of patients is inspected and treated, after they takes the preparation 15-20 days, have obvious effect, the white spot area becomes red, continue taking 45 days, 92% of the patients return to normal local pigment, the pigment recovery area is more than 85%, after continued three courses of treatment, the disease will not relapse. The preparation is capable of regulating abnormal phlegm, promoting blood-circulation and removing blood stasis, catalyzing the synthesizing of melanin cell, having remarkable effect of treating vitiligo, short curative effect, high curability, is not liable to relapse, no toxic effect deputy to make up the lack of other drugs.

The invention relates to vaginal-contracting macula-removing paste, which belongs to Chinese herba preparation. The material formulation for preparing the gel consists of herba lycopi, realgar, camphor, callicarpa bodinieri, hairyvein agrimony, lysimachia foenum-graecum, rhizoma bletillae, cannabis sativa, red flower, lotus, peach blossom and lanatechead saussurea herb with flower. The components are extracted and filtered by normal common pure water to obtain liquid supernatant; 0.1% of sodium benzoate is used for corrosion prevention; carboxymethyl cellulose is prepared into 4% of substrate by pure water and uniformly soaked, so that the stock solution is taken out and uniformly stirred with the substrate in a ratio of 1 to 1 to form a gel form; the filling volume is 3.5 grams per piece, so that gel is prepared; the gel is directly poured into focus part in the vagina for achieving the effects of cleaning uterus and detoxifying, contracting vagina and nourishing ovary and removing leukoplakia vulvae. An aromatherapy treatment effect can be achieved by long-term use. Moreover, by virtue of the long-term use, the vaginal-contracting macula-removing paste is better in vagina contracting effect, safer, more lasting, free of rebounding performance, and more beneficial to female reproduction health care and beatifying effect.

A clear aqueous formulation for topical application in the oral cavity of humans to treat leukoplakia contains water, beta-carotene, a water miscible polyol, an unsaturated fatty acid ester, and a surfactant, preferably polyethoxylated castor oil or POE(20) sorbitan monooleate The formulation preferably also contains a pharmaceutically acceptable anti-oxidant, preferably d-alpha-tocopherol (vitamin E), and is in the form of an oral rinse or as a gel well suited for spreading on gums or other parts of the oral cavity. The formulation is applied in a gel form on a substantially regular daily basis to areas in the oral cavity where leukoplakia lesions are present. Persistent application of the gel results in substantial diminution or total elimination of the leukoplakia lesions.

The invention discloses a traditional Chinese medicine composition for treating woman external genitalia white patch, which is composed by the following components by mass percentages of: white puncturevine 10%, rhizoma typhoon 30%, astragalus 50% and notopterygium root 10%; the total content of the components is 100%. The above components are mixed and made into fine powder, and can be made into concentrated capsule, pill, paste or tablet by adding common excipient. The medicament is used for treating woman external genitalia white patch, achieves the advantages of fast effectiveness, good curative effect and hardly recurrence.

A compound specified by formula (I), in particular dimethylfumarate (trans-1,2-ethylenedicarboxylic acid dimethyl ester) is provided for use in prevention or therapy of gout, acne, pyoderma gangrenosum, Vitiligo, cardiovascular disease, metabolic syndrome, diabetes and/or complications of diabetes. Also provided are a dosage form comprising said compound and a method of treatment comprising administration of said compound to a patient in need thereof.

The invention discloses a technical method for treating leucoderma based on hair follicle melanocyte stem cell transplantation. The technical method includes the following steps of extraction of hairfollicles, wherein a hair follicle unit is extracted by using an FUE technology; separation of the hair follicles, wherein individual follicalar units are separated from the hair follicle unit under an electron microscope; in-vitro culture of the hair follicles, wherein the extracted and separated individual follicalar units are cultured in a special culture medium for use to improve the survivalrate of the hair follicles; inactivation of the hair follicles, wherein the hair follicles before transplantation are inactivated with the help of a dermatoscope and a hair follicle inactivating needle; transplanting of the hair follicles, wherein a special planting needle is used for planting the inactivated hair follicles in a specific area of leukasmus. Through the hair follicle in-vitro culture technology, the FUE technology is used for extracting and separating the individual follicalar units, then the individual follicalar units are placed in the special culture medium for culture, and the inactivation of the hair follicles is achieved through the hair follicle inactivation technology. After an operation, the hair follicles only turn black and do not grow hair, the point-like multiple hair follicles can restore original color through precise planting, and the purpose of fast removing the leukasmus is achieved.

The invention relates to a vitiligo covering liquid treating both the manifestation and root cause. The liquid is prepared from the following raw materials by weight: 50-100 parts of fig leaf, 50-100 parts of duckweed, 50-100 parts of orange peel, 200-300 parts of 75% ethanol, 10-20 parts of cupric chloride, and 700-800 parts of towel gourd water. The preparation method includes the steps of: soaking the fig leaf, duckweed and orange peel respectively in water, drying and cutting them into filaments, and then fully mixing the three kinds of filaments well; adding the 75% ethanol solution to soak for 48 hours, filtering the herb residues so as to obtain a pigment solution; adding the cupric chloride into the pigment solution and mixing them uniformly; then adding the towel gourd water and fully mixing well, thus obtaining the vitiligo covering liquid. The vitiligo covering liquid of the invention has both the efficacy of natural pigments in covering leukoderma and the function of natural plant extracts in activating melanocyte tyrosinase activity so as to promote melanin generation. Therefore, the vitiligo covering liquid provided in the invention can treat both the manifestation and root cause of the disease, and is safety in use and free of adverse reactions.