459 results about "Saliva" patented technology

The invention belongs to the technical field of medical materials, and particularly relates to a tooth whitening composition and a preparation method thereof, the tooth whitening composition comprises the following components by weight: 5%-15% of hydrogen peroxide, 0.5%-1.5% of a gel matrix, 0.2%-1.0% of a thickener, 5%-10% of a humectant, 3%-8% of propylene glycol, 0.05%-0.2% of a chelating agent, 1%-3% of a sweetener, 0.1%-0.5% of sodium fluoride, and the balance of water. Aiming at the problems that an existing tooth whitening product is relatively low in pH value (most of 4.0-5.0), easy to irritate gingiva and sensitive in tooth manufacturing, and the existing tooth whitening product needs to be stored in a dark place at a low temperature and is short in whitening validity period, the pH value of the product is adjusted to 5.5-6.5, so that the product is close to oral saliva, the irritation can be reduced, the stability of the product can be ensured, the product is not easy to decompose, and the tooth whitening effect is good. Active ingredients are prevented from losing efficacy in advance, and the whitening validity period is prolonged.

The invention belongs to the technical field of electrochemical detection, and discloses an anti-pollution electrochemical saliva sensor based on fluorinated side chain polypeptide as well as a preparation method and application of the anti-pollution electrochemical saliva sensor. The fluorinated side chain polypeptide disclosed by the invention not only has excellent hydrophilicity, can form a dense hydration layer with water molecules to repel pollutants, but also has low surface energy, and the interaction between the pollutants and an interface is remarkably reduced. Through the synergistic effect, the fluorinated side chain polypeptide has better anti-pollution performance compared with traditional zwitterionic polypeptide. The anti-pollution electrochemical sensor constructed on the basis of the fluorinated side chain polypeptide can be used for directly detecting CA15-3 in saliva, the saliva does not need to be pretreated, and the detection accuracy can be comparable with that of a commercial ELISA (Enzyme-Linked Immunosorbent Assay) method.

The invention provides an application of streptococcus salivarius in fatty liver, in particular to an application of streptococcus salivarius in preparation of a product, and the product is used for at least one of the following applications: (a) losing weight or reducing body fat; (b) improving the glucose tolerance of the patient; (c) increasing the sensitivity of the patient to insulin; (d) treating, relieving and preventing liver injury; (e) treating, relieving and preventing non-alcoholic steatohepatitis; (f) fat deposition caused by high-fat and high-cholesterol diet is reduced; (g) reducing blood fat; and / or (h) improving the level of at least one of the following indexes in the liver of the mammal: total cholesterol, triglyceride, low density lipoprotein-cholesterol and free fatty acid.

A spectral sensing device and associated methods for enhanced diagnostic capabilities across medical fields are disclosed. The device incorporates multispectral, hyperspectral, and photoplethysmography technologies to analyze biological features including tongue, oral cavity, saliva, teeth, and other tissues. The system transforms any standard RGB camera into a multispectral imaging device by training machine learning models to associate RGB values with spectral values inside and outside the visible spectrum using measurements from a single pixel detector spectroradiometer. A multimodal neural network with separate processing branches analyzes spectral images, non-spectral images, and tabular data to predict microbiome composition. The system generates health risk assessments by comparing predicted microbial abundances to thresholds associated with various medical conditions. Near-infrared sensing enables blood flow monitoring, subcutaneous imaging, and assessment of physiological parameters. Convolutional neural networks enable spectral reconstruction without requiring the physical device, while supporting continuous monitoring in various form factors.

The invention relates to a nicotine buccal bag with a content fixing cavity and a preparation method of the nicotine buccal bag. The nicotine buccal bag comprises a bag body, contents and a content fixing wall, the bag body is a saliva permeable bag; the content comprises a nicotine source and a functional capsule; the functional capsule comprises a shell and an inner core; the shell is saliva impermeable and is suitable for being destroyed by external force; the inner core comprises at least one of a pH regulator solution and a flavor provider solution; the content fixing wall and the bag body are relatively fixed, and a closed content fixing cavity is formed by the content fixing wall and the bag body; and a nicotine source and a functional capsule are accommodated in the content fixing cavity. The invention also relates to a preparation method of the nicotine buccal bag. The fixing cavity enables the functional capsule to have a certain and predictable position, and storage and use are convenient.

The invention belongs to the technical field of microorganisms, and particularly relates to combined lactobacillus salivarius and application thereof in female genital tract health. The preservation number of the strain is CCTCC NO: M20231719, and the strain has good bacteriostatic ability and dendritic cell (DC) maturation / activation stimulation ability, has no potential safety problem, can regulate vaginal micro-ecological balance, prevent infection caused by exogenous bacteria, effectively improve tumor immunosuppression microenvironment, and has good application prospects. And the method has very important significance on prevention / treatment of vaginal dysbacteriosis patients, gynecological tumors and precancerous lesions thereof.

The invention relates to the technical field of nursing materials, and discloses an oral and maxillofacial nursing drainage apparatus, the oral and maxillofacial nursing drainage apparatus comprises a main pipe, an auxiliary pipe and a clamping sleeve which are integrally formed, the main pipe is provided with a drainage assembly, the drainage assembly comprises two sets of conical pipes, and the large ends of the two sets of conical pipes are fixedly connected with the two ends of the main pipe respectively. According to the oral and maxillofacial nursing drainage apparatus, by arranging the drainage assembly, when the drainage head is placed on a wound surface, a solid-liquid mixture can be drained, when the drainage cylinder is placed on the wound surface, the drainage cylinder is matched with the drainage hole to drain a liquid drainage object, natural negative pressure drainage force is generated through the height difference, and the drainage object enters the drainage collection bin through the hose, the conical pipe, the main pipe and the bent pipe; the sealing dressing is matched to improve the sealing performance, the auxiliary tube and the threaded locking valve are matched to facilitate drainage object removal, wound surface liquid accumulation, hematocele or necrotic tissue can be sucked out actively under the stable negative pressure, saliva pollution is isolated through the sealing design, and the drainage amount is measured through scale marks.

The invention relates to genetic engineering combined lactobacillus salivarius and application of the genetic engineering combined lactobacillus salivarius. The strain is classified and named as combined lactobacillus salivarius CTMT2, and the preservation number of the strain is CCTCC (China Center for Type Culture Collection) M 2025547. After an NIAAA model is injected into the stomach of an alcoholic liver mouse, the acetaldehyde level of the liver of the mouse is obviously reduced, and the alcoholic fatty liver symptom of the mouse is obviously relieved; after long-term intragastric administration of a high-glucose and high-fat modeling mouse, the acetaldehyde level in excrement of the mouse can be obviously reduced, the progress of liver fibrosis is improved, and good application prospects are achieved.

The utility model relates to a saliva suction tube which comprises a tube body, the tube body comprises a fixed straight flow section, a saliva suction front end and a bent folding section, and the two ends of the bent folding section are connected with the fixed straight flow section and the saliva suction front end respectively. The saliva suction front end is of a conical structure, a plurality of suction holes are formed in the conical surface of the saliva suction front end, and the suction holes are uniformly distributed in the saliva suction front end; a filter screen is arranged in the bent folding section, a tongue protector is arranged on the fixed straight flow section, and the tongue protector is detachably installed on the fixed straight flow section. Compared with the prior art, the device has the advantages of simple structure, flexibility in operation and the like.

Abstract Present invention discloses an oral ulcer patch which adheres to a surface of a mouth ulcer and reduces pain associated with the mouth ulcer while at the same time accelerating healing of the mouth mucosa. The oral ulcer patch comprises an anti-inflammatory agent, an analgesic agent; a healing agent; an agent that forms a protective barrier upon reacting5 with saliva in the mouth, wherein the patch adheres to the moist ulcer area inside the mouth, forms a protective barrier, releases active analgesic and anti-inflammatory agents, and wherein the application of the patch to the ulcer reduces the pain caused by the ulcer and reduces the healing time of the ulcer. 10 Abstract Present invention discloses an oral ulcer patch which adheres to a surface of a mouth ulcer and reduces pain associated with the mouth ulcer while at the same time accelerating healing of the mouth mucosa. The oral ulcer patch comprises an anti-inflammatory agent, 5 an analgesic agent; a healing agent; an agent that forms a protective barrier upon reacting with saliva in the mouth, wherein the patch adheres to the moist ulcer area inside the mouth, forms a protective barrier, releases active analgesic and anti-inflammatory agents, and wherein the application of the patch to the ulcer reduces the pain caused by the ulcer and reduces the healing time of the ulcer. 10 20 24 28 71 87 23 D ec 2 02 4 2 0 2 4 2 8 7 1 8 7 2 3 D e c 2 0 2 4 A b s t r a c t 5 1 0

The invention discloses an exosome slow-release oral soluble film based on enzyme triggering and a preparation method thereof. The oral soluble film comprises a film forming substrate, a plasticizer, a disintegrating agent, mucous membrane adhesion type enzyme-sensitive nanogel and a stable protection component. Wherein the mucous membrane adhesion type enzyme-sensitive nanogel has a three-layer functional structure: an enzyme-sensitive cross-linking core is formed by maleimide starch through gradient cross-linking, and alpha-1, 4 glucosidic bonds on a starch chain can be hydrolyzed by saliva alpha-amylase; the phospholipid-exosome composite layer is located on the surface of the core, and efficient embedding of the exosome is achieved through a pre-fusion-cold locking process; the mucous membrane adhesion layer is made of thiolated mucous membrane adhesion materials and can form disulfide bonds with oral mucosa. Self-regulation slow release insensitive to saliva alpha-amylase concentration fluctuation is realized through a gradient cross-linked structure, the problems of exosome activity loss, uncontrollable release and weak adhesion are effectively solved, and the exosome is suitable for treatment of oral mucosa diseases.

Apparatuses, systems, and methods for the collection and sampling of agents (including organisms and pathogens) to determine the health of an animal colony. A collection media is configured to collect a sample from a target animal, such as a mouse or rat. The collected sample may include dust, feces, fur, urine, saliva, or other aspect of the target animal's environment.

The utility model discloses a saliva aspirator which comprises a saliva aspirating head, an occlusion part is arranged on the saliva aspirating head, an anti-skid structure is formed on the occlusion part, a cavity is formed in the saliva aspirating head, a plurality of aspirating holes are formed in the saliva aspirating head, and the aspirating holes are communicated with the cavity; one end of the connecting tube is connected with the saliva suction head, and a circulation channel is formed in the connecting tube and communicated with the cavity. According to the saliva aspirator disclosed by the utility model, the friction force between the tooth occlusal surface and the saliva aspirating head can be increased by arranging the anti-slip structure on the occlusal part, so that the saliva aspirating head can be effectively prevented from being separated during use, the reliability of the saliva aspirator during use can be improved, and the aspirating continuity of saliva can be ensured; meanwhile, in the attachment bonding process, the teeth tightly bite the saliva suction head, and the saliva suction head can play a role similar to chewing, so that the invisible orthodontic appliance template is tightly attached to the teeth, and the attachment bonding accuracy and firmness can be improved.

The utility model relates to the technical field of oral corner protection patches, and discloses a disposable oral corner protection patch special for dental operation, which comprises an oral interior part and an oral exterior part arranged on one side of the oral interior part, and J-shaped aluminum sheets are arranged in the oral interior part and the oral exterior part. According to the disposable oral corner protection patch special for dental operation, the J-shaped aluminum sheet is completely wrapped by the medical silica gel, the effects of supporting the appearance of the medical silica gel and adjusting the thicknesses of different oral corners are achieved, the whole patch is made of the medical silica gel, the aluminum sheet is wrapped on the inner side of the patch, the high rebound resilience of the medical silica gel plays a role in buffering the oral corners, and the side face of the patch is in a half-moon arc shape. The medical polyurethane adhesive is attached to the inner side of the oral outer portion, the inner side of the oral inner portion is free of adhesive and smooth, the medical polyurethane adhesive is attached to the inner wall of the oral cavity through opening and closing of the J-shaped aluminum sheet, the outer side surfaces of the oral outer portion and the oral inner portion are rough, and slipping of instruments during operation of a doctor is prevented; the rough surface can prevent the saliva suction tube from slipping and falling off.

The utility model relates to medical auxiliary appliance related technical field more, more specifically, the utility model provides prone position ventilation air cushion, including support pad body and support part, the support part sets up in support pad body, and the support part includes with the face support air cushion, shoulder support air cushion, crotch support air cushion and knee support air cushion corresponding to the position of the limb part, the face support air cushion, shoulder support air cushion, crotch support air cushion and knee support air cushion independently sets up and is respectively through the inflation conduit with the air pump intercommunication, the shoulder support air cushion and knee support air cushion respectively are equipped with phase change material in, the face support air cushion is provided with ventilation groove, is equipped with the collecting box for receiving secretion in ventilation groove, and the collecting box setting in ventilation groove is opposite the mouth part setting, is used for receiving oral cavity secretion (such as saliva), and the secretion in the collecting box is washed and collected regularly by starting negative pressure pump and water pump, avoids the secretion stagnation and influences ventilation function.

Provided are Streptococcus salivarius and compositions comprising Streptococcus salivarius for the treatment of ENT diseases, in particular cancer therapy-induced oral mucositis and respiratory tract infections associated with cancer therapy.

The utility model relates to the technical field of medical instruments, and discloses an oral disinfection and cleaning device which comprises an upper shell, a shell top is arranged at the top of the upper shell, a movable wheel is arranged at the top of the shell top, a rectangular top is arranged at the top of the movable wheel, a first fixing seat is arranged on one side of the top of the rectangular top, and a second fixing seat is arranged on the other side of the rectangular top. A buckle is arranged at the top of the first fixing base, the buckle is connected with the first fixing base in a clamped mode, a threaded hose is fixedly arranged at the top of the buckle, a saliva suction ball is arranged at one end of the threaded hose, and a plurality of saliva suction holes are formed in the surface of the saliva suction ball. The threaded hose is connected with the saliva suction ball and the saliva suction pipe, and the saliva suction ball is driven by the vacuum pump arranged in the upper shell to suck sewage in the oral cavity into the saliva box, so that the throat is prevented from being choked by excessive sewage in the oral cavity, and the interior of the oral cavity is fresh and cool without accumulated water while the oral cavity is flushed.

A nicotine pouched product is disclosed, the pouched product comprising a pouch composition and a saliva-permeable pouch enclosing said pouch composition, the pouch composition comprising nicotine and a pouch substrate, the pouch substrate comprising water-insoluble fiber, wherein said pouch composition comprises nicotine in an amount of at least 0.25% by weight of the pouch composition, and wherein the pouched product comprises said pouch composition in an amount of no more than 400 mg.

The utility model discloses an oral and facial muscle function training device which can be worn between dentition and labial muscle or labial and buccal muscle of a patient, is used for blocking contact between the labial muscle or the labial and buccal muscle and the dentition, and comprises an approximately C-shaped blocking screen and a first expandable part, the first expandable part is at least arranged at the corresponding position, corresponding to the deepest position of the bottom of the vestibular sulcus of the patient, of the outer contour of the blocking screen, and after the oral and facial muscle function training device is worn, the first expandable part expands through saliva infiltration and abuts against the bottom of the vestibular sulcus. Thus, according to the size of the oral cavity space of a patient, the first expandable part expands after being infiltrated by saliva, does not continue to expand after meeting the bottom of the vestibular groove of the patient, and can stably abut against the position, so that the oral and facial muscle function training device can be stably worn between the dentition of the patient and the lip muscle or the lip-buccal muscle; the contact between the labial muscle or the labial cheek muscle and the dentition is blocked.

The application relates to the field of biological medicine, and particularly discloses application of saliva TP17, TP47 and TP15 specific antibodies in preparation of an auxiliary diagnostic product for neurosyphilis. Based on specific antibody immunoglobulin G (IgG) of Treponema pallidum in saliva, combined detection of saliva TP17 / IgG, TP47 / IgG and TP15 / IgG outputs a risk value of neurosyphilis of a subject, or a four combined Logistic regression discriminant model is constructed by combining serum TRUST titers, and the subject is stratified into a low-risk or high-risk group based on a preset judgment threshold, so that the comprehensive recognition capability for neurosyphilis is improved. The saliva is used as a detection sample, and the application has the advantages of non-invasiveness, convenience, easy popularization, repeatable collection and the like, and can be used for early screening, auxiliary diagnosis and clinical path management of neurosyphilis.

The three-dimensional propaganda and education model comprises a model main body, an identification assembly and a supporting base, the model main body is made of a transparent material, and an unqualified sputum specimen simulation unit (such as saliva and a polluted sputum specimen) and a qualified sputum specimen simulation unit (such as white viscous sputum, yellow viscous sputum and bloody sputum) are arranged in the model main body; each unit is of an independent cavity structure, and the sputum character is visually displayed by accurately controlling the color and viscosity and simulating particles (such as squamous epithelial cells or inflammatory cells); the identification assembly is used for clearly marking the type and the qualified standard through an identification board and a fluorescent coating; the supporting base provides stable placement. Through materialized comparison, the patient can quickly distinguish the sputum type, so that the retention quality is improved from the source, the percent of pass is remarkably improved, the nursing load is reduced, and the method has the advantages of intuition, standardization, high efficiency, safety and the like.

The utility model provides a saliva cup, and relates to the technical field of medical instruments, the saliva cup provided by the utility model comprises a cup body, a first sealing element, a tube body and a second sealing element, the cup body is internally provided with a first cavity, and the cup body is provided with a first opening communicated with the first cavity; the cup body is at least provided with a partial transparent area, and the transparent area is used for observing the interior of the first cavity; the first sealing piece can seal the first opening in an openable manner; a second cavity is formed in the tube body, and a second opening communicated with the second cavity is formed in the tube body; the second sealing piece can seal the second opening in an openable manner; the tube body is movably connected with the cup body so that the first opening can be in butt joint with the second opening.

The utility model discloses an implantation guide plate with a rubber barrier, which particularly relates to the field of dental implantation and comprises a positioning plate, rubber barrier cloth is arranged at the upper end of the positioning plate, a guide plate is arranged at the upper end of the rubber barrier cloth, a positioning groove is formed in the bottom end of the positioning plate, a clamping plate is arranged in the positioning groove, and a clamping groove is formed in the clamping plate. A positioning groove is formed in the upper end of the positioning plate, a positioning protrusion is arranged at the bottom end of the guide plate, a guide ring is fixedly arranged in the middle of the guide plate, and a guide ring in-place hole is formed in the upper end of the positioning plate. According to the utility model, the rubber barrier cloth is arranged between the positioning plate and the guide plate, can play roles in isolating moisture, isolating infection, clearing the visual field, pulling soft tissues and the like, can prevent cooling water, saliva or blood from influencing the operation of medical personnel during hole preparation, and can improve the visual field in the oral cavity and the success rate of the implant.

The invention discloses a traditional Chinese medicine composition for treating middle-jiao type diabetes as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 15-30 parts of herba eupatorii, 10-20 parts of radix astragali, 8-15 parts of radix codonopsis, 1-3 parts of gypsum, 6-12 parts of radix rehmanniae preparata, 6-12 parts of radix rehmanniae recen, 9-15 parts of Chinese yam, 18-30 parts of radix trichosanthis, 12-20 parts of rhizoma anemarrhenae, 12-20 parts of radix ophiopogonis, 9-15 parts of dendrobe, 9-15 parts of radix polygonati officinalis, 3-6 parts of safflower, 3-6 parts of coptis chinensis, 9-15 parts of radix scrophulariae, 9-15 parts of dogwood, 6-10 parts of liquorice and 9-15 parts of seville orange flower. , 9-15 parts of loquat flower, 6-12 parts of penthorum chinense pursh and 6-12 parts of angelica keiskei. The traditional Chinese medicine composition is suitable for nourishing yin, moistening the lung, clearing the stomach, clearing heat, moistening dryness and promoting the secretion of saliva or body fluid, has a positive regulation effect on blood sugar and blood fat of diabetes patients, and is used for middle-digestion diabetes.

The present application relates to the technical field of medical monitoring, in particular to a multi-dimensional evaluation method and system for the thirst degree of hemodialysis patients, which collects the saliva osmotic pressure time series signal, the pharyngeal muscle electromyogram signal and the digital analog thirst scale score filled in by the patient from a plurality of sensing terminals; accordingly, a thirst physiological marker graph reflecting physiological thirst sensation driving is established, and the scale score is checked to obtain a patient thirst state benchmark vector. The natural dialogue voice stream and the neck surface video stream of the patient during the dialysis interval are synchronously captured, from which the thirst associated keyword frequency, the voice dryness degree characteristics, and the frequency and amplitude profile characteristics of the swallowing action are analyzed to generate a behavior representation index set. The thirst state benchmark vector and the behavior representation index set are cross-modally associated and mapped to construct a dynamic thirst evaluation network, through processing the continuously input real-time data, an individualized thirst degree trajectory evolving over time is output, and objective, continuous and multi-dimensional thirst state evaluation is realized.

The invention relates to a method for determining a blood-related, individual anaerobic threshold (IAT) of a test subject (10). For this purpose, first data (D1) is obtained comprising performance values (P) describing a performance of the test subject (10), time values (T) describing a respective associated detection time and respective associated saliva lactate concentration values (KS). The first data (D1) exceeds a maximum saliva lactate concentration value (KS). The blood-related, individual anaerobic threshold (IAT) is obtained on the basis of the first data (D1) and using a data model (M). The invention also relates to a method for monitoring a blood-related, individual anaerobic threshold (IAT) of a test subject (10). The invention further relates to a method for training a data model (M) for determining a blood-related, individual anaerobic threshold (IAT). The invention further relates to a data-processing device (22), to a computer program (32), and to a computer-readable medium (30). Furthermore, the invention relates to a system (16) for determining a blood-related, individual anaerobic threshold (IAT) and to a system for monitoring a blood-related, individual anaerobic threshold (IAT).

The application discloses a traditional Chinese medicine composition for benefiting qi and moistening dryness and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine. The composition is composed of 10-15 parts of Huangqi, 10-15 parts of Guizhi, 10-15 parts of Baishao, 10-15 parts of Dazao, 10-12 parts of Zhigancao, 5-8 parts of Mahuang and 6-9 parts of Shanyurou. The preparation method is to decoct with water, add or not add accessories after concentration, and prepare oral dosage forms such as decoction and granules. The application is based on the theory of 'yang qi is soft and can nourish tendons' and 'qi can produce saliva', takes the core principle of warming yang, benefiting qi, transforming qi and producing saliva, restores the qi transformation function of the human body, transpires and transmits water and liquid to the oral cavity, and is specially used for treating xerostomia of the type of yang deficiency and saliva not ascending and the type of qi deficiency and not spreading. Through clinical observation on 180 cases, the total effective rate of the application reaches 90.8%, which is obviously better than that of traditional yin nourishing treatment (48.3%). The composition is warm and not dry, and is used for treating diseases caused by yang deficiency and unstable defensive qi, such as body deficiency cold, allergic rhinitis, spontaneous sweating and the like.

A system for tracking diet and nutrition includes an oral module configured to be affixed within a mouth of a user and including a set of salivary sensors responsive to a level of at least one nutrient. The system also includes a set of eating event sensors responsive to an eating event. The set of eating event sensors can be included in the oral module, or can be included in a body module configured to be affixed adjacent to a body part of the user.

The invention relates to the technical field of oral cavity medical instruments, in particular to an oral cavity medicine applying device which comprises a main body assembly. The moving assembly comprises an inner pipeline installed at the end of the handheld spray gun, an outer pipeline is arranged on the outer wall of the inner pipeline and is supported through supporting ribs arranged on the outer wall of the inner pipeline, and a turbine is further arranged on the inner wall of the inner pipeline; the inner pipeline and the outer pipeline are of a nested structure, gel is squeezed out around medicine and cannot interfere with the medicine, meanwhile, when ointment is conveyed, a turbine is pushed to move downwards and rotate, a combination plate is triggered to be opened to convey the medicine, then a turnover plate is opened, the gel falls around the medicine through a gel channel, and the medicine is conveyed through the gel channel. The delivery amount of the gel is in direct proportion to the dosage of the medicine, after medicine delivery is completed, the gel around the medicine is flattened through the movable scraper blade in the reset process of the turbine, the gel covers the upper surface of the medicine to form a protective film for isolating saliva, the medicine retention time is prolonged, the medicine supplementing frequency is reduced, and the treatment effect is improved.

The invention relates to the technical field of marine microorganisms, in particular to application of lactobacillus salivarius NHNK-603 in preparation of products for improving tooth color and gingivitis. The strain provided by the invention is preserved in the China Center for Type Culture Collection, and the preservation number is CCTCC NO: M 2024416. Experiments show; the NHNK-603 has the effects of inhibiting proliferation and biofilm formation of pigment-generating pathogenic bacteria, agglutinating the pigment-generating pathogenic bacteria, inhibiting melanin generation of the pigment-generating pathogenic bacteria, inhibiting hyaluronidase activity of the pathogenic bacteria, promoting growth of gingival fibroblasts, inhibiting gingival cell inflammation and apoptosis induced by the pigment-generating pathogenic bacteria, and inhibiting melanin generation of the pigment-generating pathogenic bacteria. And the product can be used for preparing products for improving tooth color and gingivitis.