The invention relates to an
oxcarbazepine sustained release tablet and a preparation method thereof. According to the method adopted by the invention, raw materials are specially treated together with an auxiliary material first to prepare
oxcarbazepine composition, and the particle size of the
oxcarbazepine composition is strictly controlled. KG-802 is added into an extra auxiliary material. According to the oxcarbazepine
sustained release tablet prepared with the method provided by the invention, the use of a large amount of a cosolvent namely
sodium lauryl
sulfate in an original developed preparation is avoided, the
toxicity of a preparation finished product to a
human body after taking is reduced, and the
pollution to the environment in a preparation process is reduced; and compared with a
reference product on sale, release curves in release media with different pH values can keep similar, the
bioequivalence of an in-vitro test is ensured, and the release curves of the release media with different pH values are more similar to one another in comparison with the preparation on sale. The oxcarbazepine
sustained release tablet provided by the invention is prepared by adopting a conventional
granulation and tabletting process, the process is simple, and the oxcarbazepine sustained release tablet is suitable for large-scale production.