94 results about "Arecoline" patented technology

The invention discloses a method for controlling cancerogens in areca catechu and preparing safe areca catechu leisure food. The method comprises the following steps: high-temperature and high-pressure cooking, ultrasonic pretreatment, marinating, baking, surface coloring, vacuum packaging, sterilization and the like. The method has the advantages that the content of arecoline and arecaidine which have the cancerigenic dangers in the areca catechu and the hardness of the products are greatly reduced, therefore, the variable hazard to lower fibers of an oral mucosa caused by areca catechu fibers is reduced, and the leisure food is safer in eating. The areca catechu leisure food prepared by the method has the advantages of low cost, good chewiness and mouthfeel, and stable property, and is well received by consumers.

The invention relates to electronic cigarette atomization liquid, in which the contained arecoline and arecoline extract can well replace nicotine, and the atomization liquid can be is accepted by smokers; according to the cigarette atomization liquid, the requirement and dependence on nicotine contained in a traditional cigarette are met; meanwhile, acetylcholine, tea polyphenol and guarana extract are added, the active ingredients are used in cooperation, so the better effects of refreshing the brain, relieving nerves and relieving fatigue are achieved, the synergistic effect is achieved, and a smoker can obtain the sufficient satisfaction.

The invention belongs to the technical field of food processing, and particularly relates to an areca catechu processing method capable of improving chewiness of areca catechu. Areca catechu fruit powder is added to areca catechu brine, wherein the mass ratio of the areca catechu fruit powder to the areca catechu brine is (3 to 10) to (90 to 97). According to the areca catechu processing method, the areca catechu fruit powder is added to the brine to obtain a mixture, the mixture is further added into the areca catechu, and effective components can be furthest exerted, so that the original chewy mouth feel of the areca catechu can be improved. The areca catechu fruit powder reserves original arecoline, phenols and the like in the areca catechu, so that original health-care functions of the areca catechu can be sufficiently realized, and the effects of refreshing and restoring consciousness, killing parasites, promoting diuresis, diminishing inflammation, promoting digestion and the like can be achieved.

The invention discloses an areca flower tea beverage which is prepared by mixing the following ingredients in parts by weight: 89 percent to 90 percent of extract liquid of areca flower, 0.2 percent to 0.4 percent of concentrated juice of passion fruit, 3.5 percent to 4.5 percent of white sugar, 5.8 percent to 6.1 percent of glucose syrup, 0.007 percent to 0.015 percent of citric acid, 0.007 percent to 0.015 percent of malic acid, 0.11 percent to 0.12 percent of caramel colour, 0.02 percent to 0.03 percent of lemon yellow and 0.1 percent to 0.2 percent of ethyl maltol. According to the invention, the process adopts areca flower to produce the tea beverage and is a big break of deep processing of conventional tropical crops; particularly, various nutrient substances beneficial to human bodies in the areca flower raw material are kept to the greatest degree by utilizing a unique production process; particularly, the tea beverage is rich in arecoline, areca polyphenol and free amino acid, has good taste, is full of nutriments and is incomparable to tea beverages obtained by processing other tea, fruit juice and dry flower raw materials.

Processes and methods of manufacturing a synthetic or imitation nicotine product are provided. One process may include the steps of providing a plurality of areca fruits, drying the plurality of areca fruits, dehusking the plurality of areca fruits to obtain a plurality of areca nuts, chopping, shredding or grinding the plurality of areca nuts into a multiplicity of areca nut particles, introducing the multiplicity of areca nut particles into a tank containing water, agitating the multiplicity of areca nut particles to create a slurry, determining an amount of arecoline in the slurry and pumping the water having the predetermined amount of arecoline through a filter and into a holding tank and evaporating the arecoline from the water. An imitation nicotine product that may include 1% to 20% arecoline by weight with other elements may then be manufactured.

The invention relates to a processing method of a green betel nut dry fruit with low arecoline content, comprising the following steps: 1. selecting betel nuts without insects and diseases, cleaning and slicing the betel nuts and removing kernels for later use; 2. preparing mixed green-protecting liquid, which contains zinc acetate with the concentration of 0.02-0.1 percent, citric acid with the concentration of 0.1-0.3 percent and potassium sorbate with the concentration of 0.02-0.1 percent; and soaking the betel nuts obtained in the step 1 in the mixed green-protecting liquid for 12-24 hours; 3. drying the soaked betel nuts in a blowing dry box with the temperature of 45-65 DEG C, and then packaging finished products in vacuum. The processing method not only effectively protects the green color of the betel nuts but also reduces the arecoline content and has simple steps and low operation cost; in addition, the prepared edible betel nuts have higher edible safety.

The invention provides a method for purifying arecoline, which comprises the steps: taking the arecoline material, removing the core, crushing, adding 5-10 times of alcohol or methanol solution with the concentration of 30-50%, refluxing and extracting for 2-3 times, recovering a reagent from an extracting solution, adjusting the pH of a concentrated solution by hydrochloric acid to be 3-5, adding macroporous resins for absorption, readjusting the pH of a lower column liquid to be 7-8, adding chloroform for extraction, using the extracting solution to recover the chloroform to obtain an oily betel nut extract, selecting a chloroform-methanol-water solvent system or a normal hexane ethyl acetate methanol-water solvent system, adopting a high-speed counter current chromatograph for separation, freezing, drying to obtain the high-content arecoline. The method adopted for producing the arecoline has the advantages of short production cycle and low cost.

The invention relates to a method for extracting arecoline from areca. The method comprises the following steps of: denucleating and crushing the areca serving as a raw material, percolating the crushed areca in aqueous solution of hydrochloric acid of which the amount is 15 to 25 times that of the crushed areca, collecting the percolate, adsorbing the percolate with a cation exchange resin column, eluting the cation exchange resin column with solution of sodium chloride of which the concentration is 1 to 4 percent and the volume is 4 to 6 times that of the column, performing ultrafiltration on the eluate in an ultrafiltration membrane system, concentrating the permeate with a nanofiltration membrane to obtain concentrated solution, adjusting the pH value of the concentrated solution to 7 to 8, distilling the concentrated solution under an increased pressure, collecting the fraction, and performing freeze dehydration on the fraction to obtain the product. The method is simply operated; a toxic reagent is not required in a preparation process; no pollution to environment is caused; the content of the product is high; and the method is suitable for industrial production.

A botanical fungicide and a preparing method thereof are disclosed. The fungicide includes 5-10 parts of matrine, 8-15 parts of an alcohol extract of sisal hemp leaves, 1-5 parts of a material named as Chinese characters 'Xiaochaihujian' by the inventor, 1-5 parts of arecoline and 10-20 parts of a water extract of artemisia annua. The matrine, the alcohol extract of sisal hemp leaves, the 'Xiaochaihujian', the arecoline, and the water extract of artemisia annua are composited into the efficient wide-spectrum nontoxic fungicide. The fungicide has good antagonistic effects on a plurality of germs, and has advantages of a high efficiency, a low cost, capability of being environmentally friendly, difficult generation of drug resistance, and no harm to humans and livestock.

The invention discloses a weight-reducing health product, prepared mainly of the following raw materials in weight shares: 10-30 shares of European Hop Flower extract comprising Humulus scandens flavonoid glycosides in 50-70%, 30-50 shares of Dogbane Leaf extract conmprising Ruta graveolens isoflavones in 60-80% and 10-30 shares of Areca Seed extract comprising arecoline in 50-70%; and auxiliary materials are added to make it into oral solution, capsules, wine preparation or solid product. The invention extracts active components from natural plants and scientifically and reasonably combines them and prepares the mixture into weight-reducing, fatness-preventing health products in various forms, having advantages of remarkable effect and no side effect.

The invention discloses a construction method of an oral submucous fibrosis (OSF) mouse model. The construction method comprises the following steps: (1) selection and grouping of animals; (2) preparation of an arecoline drinking agent; (3) feeding and killing of the animals; (4) experimental observation; (5) construction of the mouse OSF model. According to the construction method of the OSF mouse model, a Balb / c mouse is fed by the arecoline drinking agent with the concentration of 500 to 2,000 mg / L for 20 weeks, and the obtained mouse OSF model is highly similar to human OSF; the animal model is high in morbidity (100 percent) and has varieties of pathogenic sites; mucous membranes at all parts in an oral cavity can be attacked; an induction method is simple and natural; the mouse drinks water freely, so that influence caused by physical stimulation and stimulation of other chemical medicines is prevented; the effect is ideal, and the induction time is short.

The invention relates to a preparation method of a standard substance for detecting arecoline in a cosmetic. The preparation method is characterized in that a propylene glycol solution of the arecoline is mixed with cosmetic cream to form the standard substance for detecting the arecoline in the cosmetic. The formula of the cosmetic cream comprises a phase A, a phase B, a phase C and a phase D in percentage by weight, namely the phase A comprises 3 to 5 percent of stearate, 2 to 4 percent of alcohol and 10 to 14 percent of #26 white oil; the phase B comprises 38 to 42 percent of propylene glycol, 0.1 to 0.3 percent of carbomer and 36 to 42 percent of deionized water; the phase C comprises 0.1 to 0.3 percent of triethanolamine, and the phase D comprises 1.25 to 1.30 percent of phenoxyethanol and ethylhexylglycerin; and the concentration of the arecoline in the standard substance is 50 mug / g. The preparation method has the advantages that the arecoline is mixed with the cosmetic cream to form the standard substance for detecting the arecoline in the cosmetic; the standard substance is the same as that in a cosmetic sample containing the arecoline in actual use, so that detection on the arecoline in the cosmetic can accord with an application state; and the detection is relatively accurate.

The invention relates to a detection method of arecoline in betel nuts, and belongs to the technical field of analytical chemistry.A solvent extraction-gas chromatography-mass spectrometry combined method is adopted to determine the arecoline in the betel nuts.The method comprises the steps that 0.5-1.5 g of shredded betel nuts are weighed and put into a conical flask, 10-15 mL of absolute ethyl alcohol is added, ultrasonic extraction is conducted for 10-20 min, and 1-2 mL of supernatant liquid is taken, analyzed through a gas chromatography-mass spectrometer and quantified through an external standard method.The detection method can be used for detecting the content of the arecoline in the betel nuts, has the advantages that sample pretreatment is easy, operation is easy and convenient, and quantification is accurate and is easy to apply and popularize.

The invention discloses a production method of tobacco areca nuts. The method mainly comprises the following steps of selecting fresh areca nuts, washing the selected fresh areca nuts, buffing the washed fresh areca nuts, soaking the buffed fresh areca nuts in calcium hydroxide, cooking the soaked areca nuts, smoking the cooked areca nuts, performing microwave puffing, performing fermentation, performing braising to generate fragrance, performing cutting to obtain slices and removing cores, performing packaging, performing microwave sterilization and the like. Through the adoption of the production method of tobacco areca nuts disclosed by the invention, the content of arecoline and the content of arecaidine in the tobacco areca nuts can be significantly reduced, so that the increased risk that eaters suffer from oral cancer can be reduced, and the tobacco areca nuts are safe to eat; and besides, the prepared tobacco areca nuts are high in puffing efficiency, fluffy, obvious in texture layering, soft in mouth feel, good in flexibility, good in mouth feel and stable in properties. The tobacco areca nuts not only reserve traditional characteristics of being fragrant, sweet and strong, but also have the characteristics of being delicately fragrant in fruity taste, fragrant rather than greasy, unique in mouth feel and flavor.

The invention relates to a medicine composition containing arecoline, ligustrazine and paeonol, and application thereof to preparation of medicine resisting atherosclerosis. The medicine composition is suitable for preventing and treating the atherosclerosis and cardiovascular diseases related to the atherosclerosis.

The invention provides a capillary electrophoresis electrochemiluminescence detection method for arecoline in a traditional Chinese medicine betelnut extract. The method applies capillary electrophoresis ruthenium pyridine electrochemiluminescence analysis technology to the detection of arecoline in the traditional Chinese medicine betelnut extract for the first time, and has the advantages that the operation is simple, the sensitivity is high, the detection limit of arecoline is 5*10<-9> mol / L, the separation function is strong, the pollution is avoided, and the field amplified injection is realized and the separation selectivity of arecoline and coexisting media in the betelnut extract is improved by using ionic liquid BMImBF4 in a buffer. Electrochemiluminescence reagent ruthenium pyridine is reversible in reaction and high in photon yield, thus the reagent consumption is greatly reduced and the detection cost is lowered. The analysis method is green, environmentally friendly and low in sample consumption. The analysis can be finished by adopting a capillary electrophoresis electrochemiluminescence comprehensive analyzer and chemical reagents which are common in laboratory and requiring nonoliter-scale injection volume.

The invention discloses a preparation method of a champagne phenol cigarette. The fresh areca nut is dried at 30-60 DEG C and crushed to obtain areca nut dry powder. Ethanol and areca nut special enzyme are added into that areca nut dry powder for carry out biological cleavage, extraction, multi-stage separation, filtration to obtain an extracted solution; the extracted solution is separated through a column filled with arecoline molecularly imprinted polymer to obtain a solution, and the solvent is recovered under reduced pressure to obtain an extract; the extract is dried below 60 DEG C, dried extract is crushed to obtain champagne phenol. The champagne phenol is dissolved in a 45 to 90 percent ethanol to obtain a champagne phenol solution; and the champagne solution is sprayed evenly onthe shredded tobacco. The invention effectively extracts champagne phenol from fresh or dried betel nut through an innovative extraction preparation process, and the extraction rate is as high as 6%-18%. The combination of champagne phenol and cigarette of the invention can improve the excitement and taste of cigarette, not only reduce the dry prickle and irritation of cigarette, but also improvethe comfort degree of cigarette mouthfeel and the smoking quality of cigarette.

The invention provides an alkaloid-free / low-alkaloid areca-nut and a preparation method thereof. The alkaloid-free / low-alkaloid areca-nut is obtained by soaking an areca-nut in alkali liquor containing a surfactant, and the content of arecoline in the areca-nut is 0.02 wt% or below. According to the method disclosed by the invention, the alkali liquor is matched with the surfactant, so that arecoline with carcinogenic threat in the areca-nut can be fully leached out, and meanwhile, pigments and pesticide residues are effectively removed, and trace elements beneficial to a human body are reserved, tannin and polyphenol components are not influenced, and the physiological activity and the specific flavor of the areca-nut are still reserved. The method is simple in process, ingenious in design, high in operability, free of pollution, large in raw material handling capacity, low in production cost and suitable for industrial production.

The invention is applicable to the technical field of electronic cigarettes, and provides an electronic cigarette tar with betel nut efficacy and a preparation method thereof, wherein the electronic cigarette tar comprises the following components by weight: 40 to 60 parts of glycerin, 10 to 25 parts of flavors and fragrances, 25 to 40 parts of propylene glycol, and 0.5 to 2 parts of arecoline. According to the embodiment of the invention, the flavors and fragrances, the propylene glycol, the glycerin and the arecoline are mixed, all the components can be well dissolved, uniform and stable dueto good solubility of the propylene glycol to the flavors and fragrances, and after the components are atomized, steam is sucked by a human body, so that the feeling of redness, heartbeat acceleration and the like caused by eating betel nuts is obvious. By replacing chewed betel nuts with the tobacco tar, harm to the oral cavity of the human body when people chew the betel nuts is reduced, and thus the risk that people suffer from periodontitis, oral cancer and other diseases due to long-term excessive chewing of the betel nuts is reduced; and moreover, a real betel nut feeling can be experienced in the electronic cigarette tar, and the electronic cigarette tar is popular with electronic cigarette users and betel nut enthusiasts.

The invention discloses an electronic atomized liquid. The electronic atomized liquid simultaneously contains nicotine and arecoline, the nicotine is a combination of at least one of plant purified nicotine, artificially synthesized nicotine, nicotine salt and nicotine-containing tobacco extract, and the arecoline is a combination of at least one of plant purified arecoline, artificially synthesized arecoline, an areca nut extract and other substances containing arecoline. The nicotine and the arecoline are used as main components and are added into the electronic atomized liquid at the same time. By using the physiological synergistic enhancement effect of compatibility of the nicotine and the arecoline, the addiction removing performance of the electronic cigarette when the user smokes the electronic cigarette is improved, particularly, the low-concentration nicotine atomized liquid can achieve the addiction removing effect of the high-concentration nicotine atomized liquid in the past, and the risk that the electronic cigarette user turns to traditional tobacco user is reduced.

The invention provides an areca nut flavored product. The areca nut flavored product comprises arecoline salt. According to the present invention, the arecoline salt is applied to the product, such that the user can ingest the arecoline during the smoking, the effect similar to the areca nut chewing effect is produced, and the irritation is low.

The invention provides a preparation method of arecoline. On the presence of organic base, reaction raw materials such as nicotinic acid and the like have esterification and alkylation reactions with a compound capable of providing alkyl in the organic solvent, and arecoline can be prepared through a reduction reaction and aftertreatment. Two procedures including esterification and N-methylation are combined, and the process route of preparation of arecoline is shortened. According to the method, the operation conditions are simple, and the intermediate treatment is more convenient; expensive alkyl halide (such as methyl iodide) cannot be used as a reaction raw material, cheaper sulfolipid or phosphate ester compounds are selected, a good implementation effect is also obtained, and the product has a cost advantage.

The invention relates to a preparation method of a standard substance for detecting aristolochic acid A in a cosmetic. The preparation method is characterized in that a propylene glycol solution of the aristolochic acid A is mixed with cosmetic cream to form the standard substance for detecting the aristolochic acid A in the cosmetic. The formula of the cosmetic cream comprises a phase A, a phase B, a phase C and a phase D in percentage by weight, namely the phase A comprises 3 to 5 percent of stearate, 2 to 4 percent of alcohol and 10 to 14 percent of #26 white oil; the phase B comprises 38 to 42 percent of propylene glycol, 0.1 to 0.3 percent of carbomer and 36 to 42 percent of deionized water; the phase C comprises 0.1 to 0.3 percent of triethanolamine, and the phase D comprises 1.25 to 1.30 percent of phenoxyethanol and ethylhexylglycerin; and the concentration of the arecoline in the standard substance is 50 mug / g. The preparation method has the advantages that the aristolochic acid A is mixed with the cosmetic cream to form the standard substance for detecting the aristolochic acid A in the cosmetic; the standard substance is the same as that in a cosmetic sample containing the aristolochic acid A in actual use, so that detection on the aristolochic acid A in the cosmetic can accord with an application state; and the detection is relatively accurate.

The invention relates to an insecticidal and bactericidal agent with thymol and arecoline, in particular to a formula of the insecticidal and bactericidal agent with thymol and arecoline and a preparation method of the insecticidal and bactericidal agent. The insecticidal and bactericidal agent is prepared from, by weight, 1-45% of thymol, 1-25% of arecoline and the balance additives. Because few insecticidal and bactericidal pesticides exist on the market, the insecticidal and bactericidal agent will save lots of cost for vast farmers once being produced and used, and the main ingredients, namely, thymol and arecoline, used by the insecticidal and bactericidal agent are plant source ingredients extracted from the nature, can be decomposed in the natural environment, cause no pollution to crops or the environment, and belong to green pesticide. Due to the two active ingredients, namely, thymol and arecoline, the synergistic interaction effect is achieved, and it is avoided that diseases and insects resist to the agent and the control object is simplex in the use process.

The invention discloses a method for enriching arecoline by using H103 type macroporous adsorption resin. The method comprises the following steps: step one, drying and crushing areca-nut into areca-nut dry powder, soaking in distilled water, and ultrasonically extracting to obtain extracting solution; step two, adding the extracting solution in H103 type macroporous adsorption resin column dynamically adsorb the arecoline; step three, after dynamically adsorbing the arecoline, adding deionized water in H103 type macroporous adsorption resin column, washing, adding ethanol in the H103 type macroporous adsorption resin column to elute the adsorbed arecoline, collecting the eluting solution; step four, reducing pressing and concentrating the eluting solution by using rotary evaporator to obtain the arecoline. The method disclosed by the invention has the beneficial effect that the arecoline is extracted by using environment-friendly water extraction; the eluting solution is ethanol which is convenient to recycle, and the finally obtained arecoline is high in refining degree. The method is easy to operate and can be applied to large-scale production.

The invention relates to the technical field of composite formulae of traditional Chinese medicines and western medicines for livestock and in particular discloses a traditional Chinese medicine and western medicine composite preparation as well as a preparation method and an application thereof. The traditional Chinese medicine and western medicine composite preparation provided by the inventionis prepared from praziquantel, arecoline, cucurbitin, osthole and the like according to a certain ratio by using certain processes. The medicinal composition provided by the invention is simple and clear in method, easy to apply, remarkable in treatment effect due to the combination of traditional Chinese medicines and western medicines, and applicable to prevention and treatment on animal echinococcoses, and has relatively good economic benefits and social benefits.

The invention relates to the technical field of composite formulae of traditional Chinese medicines and western medicines for livestock and in particular discloses a traditional Chinese medicine and western medicine composite preparation as well as a preparation method and an application thereof. The traditional Chinese medicine and western medicine composite preparation provided by the inventionis prepared from praziquantel, arecoline, cucurbitin, osthole and the like according to a certain ratio by using certain processes. The medicinal composition provided by the invention is simple and clear in method, easy to apply, remarkable in treatment effect due to the combination of traditional Chinese medicines and western medicines, and applicable to prevention and treatment on animal echinococcoses, and has relatively good economic benefits and social benefits.

The present invention provides a manufacture method for manually re-made betel nuts. The manually re-made betel nuts are prepared by processes of dried betel nut softening, crushing, secrete preparing, molding, etc. The manufacture method maintains traditional habit and flavor of people chewing dried betel nuts, can also effectively avoid damages to oral cavity caused by the dried betel nuts during chewing, and has characteristics of wide source of the raw material, easy adjustment of size, taste, arecoline content and softness, less influence by maturity of the betel nuts, etc.

The invention relates to a Chinese medicinal composition for treating hernia. The Chinese medicinal composition mainly comprises red tuckahoe, arecoline, tangerine peel, rosa microcarpa lindl, szechwan chinaberry fruit and Chinese angelica. The Chinese medicinal composition has low cost, wide medicinal sources and high cure rates.

The invention discloses an ampullaria gigas molluscacide which comprises the following raw materials by mass: 1-20 parts of diatomaceous earth or kaolin, 10-20 parts of tea bran, 30-40 parts of sec butyl acetate, 7-15 parts of dimethyl sulfoxide, 1-15 parts of castor oil polyoxyethylene ether, 3-20 parts of beta-cyclodextrin, 3-8 parts of calcium dodecylbenzenesulfonate, 1-10 parts of sodium lignosulfonate, 5-15 parts of propylene glycol, 1-10 parts of an antifreeze, 1-10 parts of a thickening agent, 1-10 parts of a disintegrating agent and 40-60 parts of a molluscicidal active substance; and the molluscicidal active substance comprises sodium pentachlorophenate, arecoline, ginkgolic acid, gallic acid, tea saponin, isoquercetin and leonurine. The ampullaria gigas molluscacide is prepared by compounding of plant active substances and chemical drugs, the usage of the chemical drugs is reduced, environmental pollution is reduced, by compounding of the plant active substances, the molluscicidal activity of the molluscicide is enhanced, and by compounding with the harmless concentration of sodium pentachlorophenate, the molluscicidal effect is excellent.