22 results about "Arachidic acid" patented technology

The invention provides a feed additive for improving the hypoxia tolerance function of micropterus salmoides. The feed additive is prepared from the following raw materials in percentage by mass: 20% of arachidonic acid and the balance of maltodextrin. The invention also provides a feed composition of the feed additive. The feed is prepared from the following raw materials in percentage by mass: 450 per mill of fish meal, 50 per mill of fermented hermetia illucens pulp, 69.5 per mill of enzymolysis chicken powder, 60 per mill of chicken liver powder, 60 per mill of enzymolysis soybean meal, 75 per mill of fermented soybean meal, 60 per mill of cottonseed meal, 29 per mill of dextrin, 40.5 per mill of cassava starch, 23 per mill of soybean oil, 23 per mill of linseed oil, 15 per mill of monocalcium phosphate, 5 per mill of choline chloride, 1 per mill of a micropterus salmoides premix, 1 per mill of zeolite powder and 20 per mill of a feed additive. The feed composition is used for improving the hypoxia tolerance of the micropterus salmoides. According to the invention, arachidonic acid is used as a functional active substance to prepare the hypoxia stress resistant functional feed, and the addition of arachidonic acid can significantly activate liver angiogenesis genes, promote the liver angiogenesis level and improve the hypoxia tolerance of largemouth bass.

The present invention discloses a hair metabolite marker combination for diagnosing Alzheimer's disease and its application. The hair metabolite marker combination includes triacontanes, erucic acid, heneicosane, behenic acid, tetracosane, 3-hydroxybutyric acid, 15-methylhexadecanoic acid, arachidic acid, heptadecanoic acid, melatonin, stearic acid, tetracosanoic acid, heneicosanoic acid, and docosane. The present invention uses metabolomics methods to study, compare, and analyze the hair metabolites of AD patients, MCI patients, and cognitively normal subjects, explores potential biomarkers that may be contained therein, obtains a group of hair metabolite differences among AD patients, and evaluates the sensitivity and specificity of this group of substances for diagnosing AD. The present invention provides a new marker for the accurate diagnosis of AD and can be used in clinical auxiliary diagnosis of AD to improve diagnostic accuracy.

The invention discloses the technical field of animal cell culture and cell culture meat, and provides a food-grade natural compound combination method for promoting efficient myogenic differentiation in vitro. According to the method disclosed by the invention, a combination of xanthophyll and arachidic acid is added into a basic myogenic differentiation induction culture medium to form a myogenic differentiation promoting culture medium. According to the myogenic differentiation culture medium system, the myogenic differentiation efficiency of the myogenic cells can be improved from about 23% to 45% or above, the myogenic fusion efficiency can be improved from about 18% to 33% or above, the problems that the in-vitro differentiation efficiency of the myogenic cells is low, the content of key proteins such as myosin is insufficient and the like are effectively solved, and the myogenic differentiation culture medium system is suitable for large-scale popularization and application. And a feasible scheme is provided for large-scale muscle fiber production of cell culture meat.

The embodiments of the present application relate to a biomarker, application, kit and detection method for identifying highly virulent Klebsiella pneumoniae. The biomarker includes one or more of arachidic acid, 3,4-dihydroxymandelic acid, 10-hydroxystearic acid, D-arginine and caproic acid in the metabolites of highly virulent Klebsiella pneumoniae, which can accurately distinguish highly virulent Klebsiella pneumoniae from classical Klebsiella pneumoniae, and can more accurately identify highly virulent Klebsiella pneumoniae.

The invention discloses a method for preparing Aramchol through enzymatic synthesis, and belongs to the technical field of organic synthesis. The technical key points of the invention are as follows: firstly, preparing 3beta, 7alpha, 12alpha-trihydroxy-5beta-cholic acid through an enzyme catalyst with specific selectivity; the method comprises the following steps: reacting 3 beta, 7 alpha, 12 alpha-trihydroxy-5 beta-cholic acid with ammonia water to generate 3 beta-amino-7 alpha, 12 alpha-dihydroxy-5 beta-cholic acid; 3 [beta]-amino-7 [alpha], 12 [alpha]-dyhydroxyl-5 [beta]-cholic acid and methanol are subjected to esterification, such that 3 [beta]-amino-7 [alpha], 12 [alpha]-dyhydroxyl-5 [beta]-cholestane-24-acid methyl ester is generated; the preparation method comprises the following steps: carrying out condensation on 3 [beta]-amino-7 [alpha], 12 [alpha]-dyhydroxyl-5 [beta]-cholestane-24-acid methyl ester and arachidic acid to generate 3 [beta]-amino-7 [alpha], 12 [alpha]-dyhydroxyl-5 [beta]-cholestane-24-acid methyl ester, and then hydrolyzing to obtain Aramchol. The method overcomes the defects that in a chemical synthesis method in the prior art, the number of exposed reaction sites of three hydroxyls of 3alpha, 7alpha, 12alpha-trihydroxy-5beta-cholic acid is large, the consumption of sodium azide and arachiyl chloride is large, side reactions are complex, and reproducibility is poor. The method for synthesizing and preparing the Aramchol by using the enzymatic method is simple to operate and convenient in post-treatment, the process yield of the method is as high as 91% or above, and the method is suitable for industrial production.

The invention provides arabinoxylan-bifidobacterium longum synbiotics and application of the arabinoxylan-bifidobacterium longum synbiotics in regulation of arachidic acid metabolism, and belongs to the technical field of microbial preparations. The preparation method of the arabinoxylan-bifidobacterium longum synbiotics comprises the following steps: mixing prefermented bifidobacterium longum and arabinoxylan, adding a mixed solution of sodium alginate and chitosan for embedding, and freeze-drying to obtain the arabinoxylan-bifidobacterium longum synbiotics. According to the invention, bifidobacterium longum is taken as probiotics, araboxylan is taken as prebiotics, sodium alginate-chitosan nanoparticles are taken as an embedding carrier, and a nano embedding technology is adopted, so that the gastrointestinal tract tolerance of the synbiotics is remarkably improved, and the bioavailability of the synbiotics is enhanced; compared with the single use of prebiotics or probiotics, the synbiotics have a better effect of regulating SCFAs and arachidonic acid metabolism, can influence inflammatory factors through intestinal flora-SCFAs-arachidonic acid metabolic axis, and have a wide application prospect on chronic inflammation related diseases.

The present application relates to a kind of methods for improving the biological activity of Bacillus thuringiensis preparation using organic acid.The method is specifically as follows: adding organic acid to Bacillus thuringiensis preparation, thereby improving the biological activity of Bacillus thuringiensis preparation;The Bacillus thuringiensis preparation is Bacillus thuringiensis wettable powder;The organic acid is selected from any one or more of palmitic acid, stearic acid, arachidic acid, acetylsalicylic acid and oleic acid;The biological activity includes any one or more of biofilm formation ability, ultraviolet resistance and insecticidal activity.By the method of the present application, the application effect of Bacillus thuringiensis preparation in agriculture can be significantly improved, and has high practical application value.

The invention discloses a demulsification conditioning agent for extracting oil from palm oil wastewater, and belongs to the technical field of range, the conditioning agent is composed of polypropylene glycol, oleamide and high-carbon carboxylic acid; the demulsification conditioning agent product produced by using the high-carbon carboxylic acid as one of decanoic acid and arachidic acid has good stability, does not demulsify after long-term storage, is controllable in cost, can efficiently separate illegal cooking oil in palm oil production wastewater and kitchen wastewater, has similar and rapid production processes of different products, can adjust the formula proportion according to the characteristics of different wastewater, and is suitable for industrial production. Therefore, the optimal demulsification and tempering effect is achieved. Aiming at wastewater with relatively high oil content, the dosage of oleamide can be properly increased, so that the lipophilicity of the demulsifying and conditioning agent is improved; and for wastewater with relatively high water content, the proportion of polypropylene glycol can be increased, so that the hydrophilicity of the demulsifying and conditioning agent is enhanced. In addition, the demulsifying and conditioning agent is environment-friendly in the using process, does not generate secondary pollution, and meets the current environmental protection requirement.

The application discloses application of white atractylodes rhizome in increasing content of fatty acids in eggs, and further discloses a method for increasing content of fatty acids in eggs, which is to feed laying hens with additives prepared from white atractylodes rhizome. The application can effectively increase content of fatty acids such as palmitic acid, palmitoleic acid, oleic acid, stearic acid, arachidic acid, alpha-linolenic acid and DHA in eggs by feeding laying hens with additives prepared from white atractylodes rhizome, but the change of content of cholesterols is not obvious, so that the additive is a very ideal nutritional additive, and provides a simple and convenient method for obtaining high-fatty-acid and low-cholesterol eggs.

The application discloses a KASP molecular marker related to quality traits of Brassica napus and application thereof, and belongs to the technical field of molecular genetics.The application discloses the KASP molecular marker related to quality traits of Brassica napus and a primer thereof, and application of the KASP molecular marker and the primer in genotyping or quality trait identification of Brassica napus.The results show that the application can accurately identify genotypes, has high sensitivity and specificity, and effectively reduces the error rate.The application further discloses a Brassica napus genotyping / quality identification method.The results show that a material with a genotyping result of AA has the characteristics of low erucic acid, low glucosinolate, high oleic acid, high linoleic acid, low arachidic acid and low protein content; a material with a GG type shows high erucic acid, high glucosinolate, low oleic acid, low linoleic acid, high arachidic acid and high protein content.The application can quickly screen out individuals with excellent quality traits in early generations, and avoids the long process of identifying traits after plants mature in traditional breeding.

The invention relates to an ultra-long-chain glucosyl nonionic surfactant and a synthesis method thereof. The surfactant is synthesized in one step through selective amination reaction catalyzed by DMAP by taking plant-based fatty acid such as arachidonic acid, behenic acid or xylinic acid as a hydrophobic tail chain and glucose derivatives such as meglumine and glucamine as a hydrophilic head group. According to the method, the hydroxyl protection / deprotection step in the traditional process is innovatively avoided, and the synthesis path is remarkably simplified. Methanol, ethanol or chloroform (single or mixed solvent) is used as a reaction medium, and the product is purified by combining an industrial crystallization method, so that the method has the advantages of simple process and low cost, and is suitable for large-scale production. The raw materials of the obtained super-long-chain glucosyl nonionic surfactant are all derived from agricultural product processing products such as rapeseeds, nuts and glucose and have reproducibility and environmental compatibility, and the characteristic of easy biodegradation of the super-long-chain glucosyl nonionic surfactant conforms to the green chemical principle.

To provide elovanoid hydroxylated derivatives as very-long-chain polyunsaturated fatty acids, and methods of use.SOLUTION: The present invention provides methods of use related to omega-3 very-long-chain polyunsaturated fatty acids (n-3 VLC-PUFA) and their hydroxylated derivatives known as elovanoids to alleviate a symptom of, treat, or prevent a disease, and further provides compositions and methods for modulating VLC-PUFA bioactivity and availability.SELECTED DRAWING: Figure 1

The invention discloses a method for determining organic acids in main stream smoke of cigarettes, which is used for determining 16 organic acids in the main stream smoke of the cigarettes. The 16 organic acids are respectively crotonic acid, tiglic acid, trans-2-methyl-crotonic acid, levulinic acid, benzoic acid, furoic acid, lauric acid, tetradecanoic acid, cinnamic acid, palmitic acid, stearic acid, oleic acid, linoleic acid, nonadecanoic acid, linolenic acid and arachidic acid; the method comprises the following steps: capturing flue gas, oscillating and extracting, preparing a standard solution, preparing a solution to be detected, qualitatively analyzing and quantitatively analyzing. By adopting the method, the 16 organic acids in the mainstream smoke of the cigarette can be accurately determined.

The invention relates to the technical field of biomedicine, in particular to a serological biomarker for diagnosing chronic obstructive pulmonary disease. The marker is selected from the group consisting of myristic acid, oleic acid, stearic acid, eicosapentaenoic acid, arachidic acid, docosahexaenoic acid, docosapentaenoic acid, docosatetraenoic acid, nervonic acid, wood tar acid, arginine and glutamine. The combined marker has relatively high sensitivity and specificity, can provide reliable diagnosis information in an early stage or an atypical stage of symptoms, and overcomes the limitations of dependence on lung function detection, insufficient sensitivity, complex operation and the like of the existing diagnosis means; therefore, a convenient and accurate detection tool capable of being popularized is provided for early screening, risk prediction and clinical diagnosis of the chronic obstructive pulmonary disease.

To provide Areca catechu seed flavored products containing arecoline salts.SOLUTION: Arecoline salt is obtained by neutralizing arecoline with a compounding acid. The compounding acid is at least one of formic acid, acetic acid, propionic acid, butyric acid, isovaleric acid, 2-methylbutyric acid, valeric acid, 3-methylvaleric acid, 2-methyl-2-pentenoic acid, trans-2-hexenoic acid, hexanoic acid, heptanoic acid, octanoic acid, 2-nonenoic acid, capric acid, dodecanoic acid, tetradecanoic acid, hexadecanoic acid, octadecanoic acid, arachidic acid, salicylic acid, oxalic acid, citric acid, sorbic acid, tartaric acid, adipic acid, hydrochloric acid, hydrobromic acid, and the like. A product is an aerosol, chewing gum, or filter capsule.SELECTED DRAWING: None

The invention discloses a method for efficiently preparing arachidic acid and behenic acid by adsorbing and decontaminating raw materials through bio-based calcium oxide, and relates to the field of grease chemical engineering, the method comprises the following steps: S1, high-erucic acid rapeseed oil raw materials are subjected to decontaminating treatment through an adsorption column filled with bio-based calcium oxide, and the bio-based calcium oxide is prepared by calcining aquatic organism shells; s2, carrying out acidic hydrolysis on the impurity-removed raw material to obtain mixed fatty acid; according to the method for efficiently preparing the arachidic acid and the behenic acid by adsorbing and removing impurities from the raw materials through the bio-based calcium oxide, the bio-based calcium oxide is prepared from waste shells, high-value utilization of waste is achieved, and the cost is low. The material has a high specific surface area and abundant mesopores, and shows a selective adsorption capacity far higher than that of common calcium oxide on polar impurities such as thioglycoside and colloid, the removal rate can reach 88% or above, and the purity of the raw materials is guaranteed from the source.

The invention relates to a method for improving biological activity of a bacillus thuringiensis preparation by using organic acid. The method specifically comprises the following steps: adding organic acid into a bacillus thuringiensis preparation so as to improve the biological activity of the bacillus thuringiensis preparation; the bacillus thuringiensis preparation is bacillus thuringiensis wettable powder; the organic acid is selected from any one or more of palmitic acid, stearic acid, arachidic acid, acetylsalicylic acid and oleic acid; the biological activity comprises any one or more of biofilm forming ability, anti-ultraviolet ability and insecticidal activity. By means of the method, the application effect of the bacillus thuringiensis preparation in agriculture can be remarkably improved, and the method has high practical application value.

This invention discloses the application of a metabolic biomarker in the preparation of products for diagnosing ASD and ADHD, which has the advantages of high sensitivity, high specificity, and high accuracy, and can reflect the severity of the disease and comorbidities. The biomarker is one of the following: linoleamide, valeric acid, androstenedione sulfate, arachidic acid, or uric acid.

This invention relates to a method for the direct synthesis of Aramchol from cholic acid, belonging to the field of organic synthesis technology. The key technical point of this invention is the method for the direct synthesis of Aramchol from cholic acid. First, eicosanoyl chloride is prepared from arachidic acid and thionyl chloride. Then, eicosanoamide is prepared from eicosanoyl chloride and ammonia-methanol solution. The eicosanoamide is added to tetrahydrofuran, followed by the addition of cholic acid, diethyl azodicarbonate, and triphenylphosphine. Aramchol is synthesized under the action of diethyl azodicarbonate and triphenylphosphine. This method overcomes the shortcomings of existing techniques for synthesizing Aramchol from cholic acid, such as excessively long reaction routes, large consumption of sodium azide and eicosanoyl chloride, complex side reactions, and poor reproducibility. The preparation method involves reactions at room temperature, is simple to operate, has short steps, convenient post-processing, and high yield, making it suitable for industrial application.

The invention discloses a preparation method of precipitated silica for a low-wear conveyor belt, belonging to the technical field of silica preparation, comprising the following steps: adding ethyl 3-ethoxypropionate into a reactor, and using the ethyl 3-ethoxypropionate as a solvent of the whole reaction system; arachidic acid and a solvent are added into the reactor and stirred for 5 min, the stirring speed at the beginning is 100 r / min-150 r / min, the stirring speed is gradually increased to 200 r / min-250 r / min after stirring is conducted for 1 min-2 min, and finally the stirring speed is kept at 300 r / min-350 r / min after stirring is completed for 5 min; the arachidic acid can be prepared by hydrolyzing and separating peanut oil, the arachidic acid is C20 acid, is small in acidic side effect and high in purity, has oxidation resistance, can improve the thermo-oxidative aging resistance and corrosion resistance of rubber products, and meanwhile, as a sustainable substitute, an environment-friendly ester product will become a mainstream in the future. The method is not only environment-friendly, but also can promote sustainable development of economy and society.

The invention discloses a preparation method of tensile plant-based cobalt salt, and belongs to the technical field of preparation of cobalt salt, the preparation method comprises the following steps: adding ethyl 3-ethoxypropionate into a reactor, and using the ethyl 3-ethoxypropionate as a solvent of the whole reaction system; arachidic acid and a solvent are added into the reactor and stirred for 5 min, the stirring speed at the beginning is 100 r / min-150 r / min, the stirring speed is gradually increased to 200 r / min-250 r / min after stirring is conducted for 1 min-2 min, and finally the stirring speed is kept at 300 r / min-350 r / min after stirring is completed for 5 min; the arachidic acid can be prepared by hydrolyzing and separating peanut oil, the arachidic acid is C20 acid, is small in acidic side effect and high in purity, has oxidation resistance, can improve the thermo-oxidative aging resistance and corrosion resistance of rubber products, and meanwhile, as a sustainable substitute, an environment-friendly ester product will become a mainstream in the future. The method is not only environment-friendly, but also can promote sustainable development of economy and society.

The invention discloses a hair metabolism marker composition for diagnosing Alzheimer's disease and application of the hair metabolism marker composition. The hair metabolism marker combination comprises triacontane, erucic acid, heneicosane, behenic acid, tetracosane, 3-hydroxybutyric acid, 15-methylhexadecanoic acid, arachidic acid, heptadecanoic acid, melatonin, stearic acid, tetracosane acid, heneicosane acid and docosane. According to the invention, hair metabolism components of AD patients, MCI patients and normal cognitive people are researched, compared and analyzed by a metabonomics method, potential biomarkers possibly contained in the hair metabolism components are explored, a hair metabolism difference group of the AD patients is obtained, and the group of substances is evaluated for diagnosing the sensitivity and specificity of AD. The invention provides a new marker for accurate diagnosis of AD, can be used for clinical auxiliary diagnosis of AD, and improves the accuracy of diagnosis.