Disclosed is a perinereis aibuhitensis totally-artificial breeding technology. The technical processes of the perinereis aibuhitensis totally-artificial breeding technology include the steps of parent perinereis aibuhitensis selection, indoor cement pit culturing, daily management, sexual maturity, artificial regulation for breeding, centralized hatching, young perinereis aibuhitensis breeding, soil pool breeding, culturing management and harvesting. Through research on perinereis aibuhitensis domestication breeding, artificial parent perinereis aibuhitensis cultivation, the artificial insemination method, young perinereis aibuhitensis production and large-scale cultivation, the perinereis aibuhitensis artificial cultivation and artificial breeding technologies and the perinereis aibuhitensis production processes are formed, the problems that young perinereis aibuhitensis supply is not enough and limited by seasons are solved, perinereis aibuhitensis fertilization rates, hatchability which is about 60% and young perinereis aibuhitensis survival rates are improved, and guarantees in quality and quantity are provided for artificial breeding in the future; furthermore, the perinereis aibuhitensis totally-artificial breeding technology has significance in conducting large-scale perinereis aibuhitensis cultivation, improving cultivation structure adjustment, increasing income of fishermen and guaranteeing the sustainable development of the marine aquaculture industry.