The invention discloses an indoor intensive production method of perinereis aibuhitensis seeds, belonging to the field of aquaculture. The method comprises the steps of preparing a cement pond, preparing mud for culturing, preparing perinereis aibuhitensis culture boxes, distributing larva seeds, breeding the seeds, daily managing and enabling the seeds to emerge. In the cement pond, the multiple layers of small perinereis aibuhitensis culture boxes are arranged in a staggered stacking way, the attachment surface area of larvae in the cement pond can be increased, indoor intensive high-density production of the perinereis aibuhitensis seeds is realized, the seed output of the cement pond of a unit water body is increased, outdoor earth pond culture is not needed, the seeds with the large size of 20 to 30mm are directly obtained, and large-scale intensive production of the seeds is realized; if the perinereis aibuhitensis seeds are sold or broadcast remotely, the perinereis aibuhitensis seeds can be conveyed with the boxes and soil, convenience and quickness are realized, and damage caused in the collection, transfer and conveying processes of perinereis aibuhitensis larvae is avoided.