5results about How to "Good energy" patented technology

This invention discloses a chitosan-based hydrogel contraceptive material, its preparation method, and its applications, relating to the field of contraceptive materials technology. The material comprises: perfluoroalkyl chain modified chitosan: 1-5 wt%; sodium β-glycerophosphate: 3-10 wt%; polyacrylic acid: 0.5-3 wt%; spermicide: 0.1-5 wt%; silver nanoparticles: 0.01-0.1 wt%; chitosan oligosaccharide: 0.1-1 wt%; lactic acid bacteria metabolites: 0.05-0.5 wt%; and lactic acid aqueous solution: balance to 100%. The thermosensitive gelation mechanism of this invention utilizes perfluoroalkyl chain modified chitosan, which is a material with a lowest critical solution temperature (LCST) of 37°C. The complex interaction between the spermicide and the gel matrix consists of intermolecular van der Waals forces and hydrogen bonds.

This invention discloses a herbal compound-based hair growth and anti-hair loss conditioning cream and its low-temperature preparation process, relating to the fields of cosmetics and scalp care technology. Specifically, it is a herbal compound-based hair growth and anti-hair loss conditioning cream and its low-temperature preparation process. The conditioning cream contains, by weight, herbal active ingredients such as ginseng, arborvitae leaf, duckweed, soapberry, angelica, chuanxiong, rosemary, ginger, asarum, and mulberry bark, as well as functional and matrix excipients such as sodium hyaluronate, cocoyl glucoside, carbomer 940, phenoxyethanol, and ethylhexylglycerin. Its preparation process employs low-temperature treatment throughout, including low-temperature extraction at room temperature to 50℃ and ultrasonic extraction at 200-800W, as well as low-temperature blending with low-speed stirring at 25-40℃, effectively preserving the active herbal ingredients. This product can improve scalp microcirculation, repair hair follicles, and regulate sebum secretion, suitable for various types of hair loss, while also relieving scalp itching and repairing damaged hair.

The invention discloses an N-methyl nitrosamide compound as well as a pharmaceutical composition and application thereof. The compound (formula I) is a hypoxia-activated NO donor drug, has the characteristic of effectively releasing NO under a high-selectivity hypoxia condition, so that the activity of myocardial cells is remarkably improved, the in-vivo and in-vitro activity is excellent, and the compound can be used for preventing or treating myocardial hypoxia injury. Meanwhile, the metabolic stability of the compound is improved by an ether bond connection structure, so that the compound has in-vivo metabolic properties beneficial to patent medicines.

The application provides a method for cryopreservation and ultra-cryopreservation of the sperm of feed domesticated mandarin fish, and first provides a cryopreservation diluent for the sperm of the mandarin fish, which comprises Hanks solution, sodium chloride, soybean lecithin, vitamin E, curcumin, melatonin and SOD; an anti-freezing protective agent is added in the cryopreservation diluent to obtain an ultra-cryopreservation anti-freezing solution for the sperm of the mandarin fish; the sperm of the mandarin fish is mixed with the cryopreservation diluent to realize cryopreservation; and the sperm of the mandarin fish is mixed with the ultra-cryopreservation anti-freezing solution to realize ultra-cryopreservation. The cryopreservation diluent for the sperm of the mandarin fish can realize cryopreservation of the sperm of the mandarin fish, and the sperm can be ultra-cryopreserved after the addition of the anti-freezing protective agent, so that the persistence of the preservation time of the sperm of the mandarin fish is ensured, the protection effect on the sperm is good, the activation rate of the sperm after thawing is high, and the sperm has good vitality.

This invention discloses a macrophage digestion solution and a method specifically for macrophage digestion, comprising the following components: 3-6 parts ethylenediaminetetraacetic acid (EDTA), 4-8 parts ethylene glycol bis(2-aminoethyl ether)tetraacetic acid (EDTA), 8-12 parts fetal bovine serum (FBS), and 90-100 parts phosphate buffer. The method specifically for macrophage digestion includes the following steps: preparing a stock solution of digestion solution, filtering it, and storing it at low temperature for 6 months to obtain the macrophage digestion solution; adding the macrophage digestion solution to a macrophage culture flask; shaking the macrophage culture flask containing the digestion solution to ensure even coverage; adding DMEM culture medium to the settled macrophage culture flask to neutralize the digestion solution, and transferring it to a centrifuge tube; centrifuging the solution in the centrifuge tube at room temperature for 3 minutes; and adding DMEM culture medium to the centrifuge tube after centrifugation to complete the macrophage digestion. This invention achieves high macrophage digestibility and low differentiation rate.