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Cinnamomum is a genus of evergreen aromatic trees and shrubs belonging to the laurel family, Lauraceae. The species of Cinnamomum have aromatic oils in their leaves and bark. The genus contains over 300 species, distributed in tropical and subtropical regions of North America, Central America, South America, Asia, Oceania, and Australasia. The genus includes a great number of economically important trees.
A renormane type diterpene, its preparation method and hepatoprotective use
PendingCN122255090AHepatoprotective activity hasdamage reliefOrganic active ingredientsOrganic chemistryHepatoprotective DrugsCinnamomum
The application discloses a rhynoxanthine type diterpene and a preparation method and application thereof; the rhynoxanthine type diterpene is separated from the bark of Cinnamomum cassia, and has at least one of structural formulae as shown in formula (I), formula (II) and formula (III); the rhynoxanthine type diterpene is separated from the bark of Cinnamomum cassia in the Lauraceae Cinnamomum plant; the application uses an alcohol, palmitic acid and other induced liver cell damage models to evaluate hepatoprotective activity, finds that the rhynoxanthine type diterpene can effectively relieve alcohol, palmitic acid and other induced liver cell damage, and indicates that the rhynoxanthine type diterpene has hepatoprotective activity, can be used for preparing hepatoprotective drugs, and has a good research and development prospect.
Owner:JINAN UNIVERSITY