The invention discloses a traditional Chinese medicine preparation used for treating perianal eczema, and a preparation method, and belongs to the field of traditional Chinese medicine.The traditional Chinese medicine preparation is prepared from luffa, the root bark of shaggy-fruited dittany, hairyvein agrimony, Hemigraphis procumbens (Lour.) Merr., sophora flavescens, ovateleaf holly bark, caesalpinia sepiaria, Eurya chinensis R.Br., roots and all grass of Gymnopteris bippinnata var.auriculata (Fr.) Ching, sargent craneberrybuch branchlet and leaf, Rheum delavayi Franch., leaves of Cinnamomum burmannii(Nees) B1., amur cork-trees, linseed, the roots of Aristolochia moupinensis Franch.and pepper.The medicinal materials are compatible, complement one another and have the functions of cooling blood, eliminating toxin, clearing away heat and dry dampness, dispelling wind and arresting itching, achieving astringing, stopping bleeding, killing insects and the like, all the medicinal materials are used in cooperation for directly arriving at diseased regions, and the traditional Chinese medicine preparation has the advantages of being rapid in effect, high in cure ate, free of toxic and side effects, safe and convenient to use when treating symptoms such as fever, rash, private part erubescence, scale type crusta, erysipelas type appearance, pruritus, papule, macula and the like caused by perianal eczema.The traditional Chinese medicine preparation is low in price, easy to prepare and worthy of wide clinical application and popularization.