176 results about "Monoterpene" patented technology

The invention discloses production of terpenoids and a strain, and belongs to the technical field of bioengineering. The serratia marcescens engineering bacteria for producing the semi-terpenoids or monoterpenoids are constructed, and can be used for producing linalool, isoprene, isopentenol, 1, 3, 4-triterpenes and 1, 3, 4-triterpenes. The composition is prepared from 1, 8-cineole, alpha-pinene, pinene, gamma-terpinene, geraniol, (+)-limonene, (-)-limonene, myrcene, beta-ocimene, sabinene, (-)-alpha-bisabolol, (-)-alpha-bisabolol, longifolene, wallenenes, beta-elemene, farnesene, patchouli alcohol, acyclic terpene and alpha-santalene. In a 30L fermentation tank, the yield of linalool produced by the serratia engineering bacteria is 40.72 g.L <-1 >.

The invention relates to a manufacturing method of high-density aviation fuel, in particular to an aviation fuel mixture based on monoterpenoids and a preparation method of the aviation fuel mixture. Comprising monoterpenoids, polyhydric alcohols and a catalyst which serve as raw materials, and the mass ratio of the raw materials to the polyhydric alcohols is 1: 1. The conversion rate is high, the treatment steps are reduced, the thermal stability and combustion gravimetric heat of the product are improved, and the method is suitable for preparing aviation fuel with high density, low viscosity and low-temperature performance; cyclization and hydrogenation are carried out through a one-pot method, a reaction container does not need to be transferred, and the operation is simple; according to the polyol solvent system, cyclization of the monoterpenoids becomes easier due to participation of polyol, and the conversion rate is increased; according to the dual-catalyst system, a combination of an acidic catalyst and a heterogeneous hydrogenation catalyst is used in a reaction container, so that efficient dehydration and hydrogenation reactions are ensured; the aromatic compound content in the fuel can be controlled by adjusting hydrogenation conditions.

The invention discloses a phoebe zhennan PzGGPS12 gene and application of the phoebe zhennan PzGGPS12 gene to improvement of yield and drought tolerance of plant terpenoids, and belongs to the field of genetic engineering, a key enzyme gene PzGGPS12 for catalyzing biosynthesis of the terpenoids in phoebe zhennan wood is screened and analyzed, and a full-length CDS nucleic acid sequence of the PzGGPS12 is obtained. Transgenic experiments prove that overexpression of the gene improves the relative content of tobacco monoterpenes and triterpenes. Short-term drought experiments prove that overexpression of the gene can promote biosynthesis of sesquiterpenes, diterpenes and triterpenes so as to enhance drought tolerance of transgenic tobacco. Therefore, the gene can be introduced into a plant as a target gene, the yield of terpenoids in the plant is increased, and the drought tolerance of the plant is enhanced so as to improve the variety of the plant.

The invention belongs to the field of medicines, and relates to a compound derived from Sinkiang lithospermum, a preparation method thereof and application of the compound in prevention and treatment of cardiovascular diseases. Specifically, the invention discloses a monoterpene benzoquinone derivative with a novel structure in Sinkiang lithospermum, a preparation method of the monoterpene benzoquinone derivative and application of the compound in preparation of anti-myocardial injury drugs. An in-vitro anti-myocardial cell injury activity experiment proves that the compound has a remarkable protection effect on isoprenaline (ISO)-induced H9C2 cell (rat embryo myocardial cell) injury and hypoxia-reoxygenation-induced H9C2 myocardial cell injury. The result shows that the compound can be used for preparing the anti-cardiovascular disease medicine.

The invention discloses a preparation method and application of monoterpene Trichodesmic acid, and relates to the technical field of medicines and phytochemistry, the structural formula of the Trichodesmic acid is # imgabs0 #, and the molecular formula of the Trichodesmic acid is C10H16O5; the invention relates to application of Trichodesmic acid in prevention and treatment of meloidogyne incognita. Trichodesmic acid is separated from janapan seeds, and the compound has relatively strong nematicidal activity on meloidogyne incognita.

The present invention relates to using monoterpene or sesquiterpene to permeabilize the blood brain barrier. The present invention relates to a method of treating a central nervous system (CNS) cancer wherein perillyl alcohol (POH) is administered to a mammal before or concurrently with a therapeutic agent that is a chimeric antigen receptor T-cell (CAR-T cell). The POH and CAR-T cells can be administered by intraarterial injection. The CNS cancer can be a malignant glioma, pilocytic astrocytomas (grade I), meningiomas, metastatic brain tumors, or pituitary adenomas.

The invention discloses application of protein and related biological materials thereof in promoting accumulation of grape fruit monoterpene in the field of variation or genetic engineering. The technical problem to be solved by the invention is how to improve the monoterpene content of grape fruits. A technical scheme to be protected by the invention is application of a protein with an amino acid sequence as a sequence 2 in a sequence table in increasing the content of grape fruit monoterpenes. Experiments prove that VvHYH from grapes can promote accumulation of monoterpene substances of grape fruits and leaves, and the VvHYH can be applied to grape flavor improvement and breeding.

The invention discloses a method for producing terpenoids, and belongs to the technical field of bioengineering. The serratia marcescens engineering bacteria for producing the semi-terpenoids or monoterpenoids are constructed, and can be used for producing isoprene, isopentenol, 1, 3, 4-triterpenes, 1, 3, 4-triterpenes and the like. The composition is prepared from 1, 8-cineole, alpha-pinene, pinene, gamma-terpinene, geraniol, (+)-limonene, (-)-limonene, myrcene, beta-ocimene, sabinene, (-)-alpha-bisabolol, (-)-alpha-bisabolol, longifolene, wallenenes, beta-elemene, farnesene, patchouli alcohol, acyclic terpene and alpha-santalene. In a 30L fermentation tank, the yield of linalool produced by the serratia engineering bacteria is 13.49 g.L <-1 >.

The present invention relates to using monoterpene or sesquiterpene to permeabilize the blood brain barrier.

The invention provides a function and application of a transcription factor NAC42. The invention discloses a novel gene NAC42 which is closely related to regulation and control of phytoalexin, volatile monoterpenes and sesquiterpenes of plants (so as to regulate and control insect resistance). The invention provides a new way for improving the insect resistance of plants.

To provide a solid bath agent containing monoterpene that prevents interference with the opening and closing of a resin fitting even after prolonged storage in a flexible package equipped with a resin fitting.SOLUTION: A solid bath agent contains at least one selected from the group consisting of carbonate (A) and inorganic salt (B), monoterpene (C) and nonvolatile oil component (D), where the mass ratio of monoterpene (C) to the nonvolatile oil component (D) ((C) / (D)) is 1.0 or less.SELECTED DRAWING: None

The present invention relates to an alcohol acyltransferase capable of esterifying a tertiary monoterpene alcohol, preferably within 36 hours, 24 hours, 18 hours, 12 hours, 6 hours, 3 hours, 2 hours, 1 hour, 45 minutes, or 30 minutes, more preferably in a microbial cell, so that at least 30% by weight of the tertiary monoterpene alcohol is esterified. The present invention further relates to a nucleic acid comprising a nucleic acid sequence encoding the alcohol acyltransferase of the present invention or a complementary sequence thereof, and a vector or genetic construct comprising the nucleic acid of the present invention. The present invention also provides a host cell comprising the vector or genetic construct of the present invention, and a transgenic non-human organism comprising the nucleic acid of the present invention, the vector or genetic construct of the present invention, or the host cell of the present invention. The present invention also relates to a method for preparing a monoterpene ester, which method comprises esterifying a monoterpene alcohol to a monoterpene ester in the presence of the alcohol acyltransferase of the present invention. Specifically, it provides a method for preparing linalyl acetate, which comprises esterifying linalool to linalyl acetate in the presence of the alcohol acyltransferase of the present invention.The present invention further provides (i) heterologous reconstitution of terpene biosynthetic pathways; (ii) for producing industrial products, preferably flavors or fragrances, biofuels, fuel compositions, fuel compounds, e.g., foaming agents for diesel fuel compositions, pesticides, insect repellents or antimicrobial agents; (iii) for producing aliphatic and / or aromatic monoterpene esters from monoterpene alcohols, preferably from tertiary monoterpene alcohols; (iv) for detoxifying monoterpene alcohols in microorganisms, thereby increasing monoterpene production in said microorganisms; (v) for combining monoterpene alcohols with GPP synthase and / or S- or R-linalool synthase; (vi) to enhance the beneficial effect of acetylation in that the hydrophobic acetate partitions more readily into the organic phase compared to the monoterpene alcohol; (vii) to express the alcohol acyltransferase of the invention so that the ratio of monoterpene acetate to monoterpene alcohol is greater than 5:1 or 10:1; or (viii) in a microbial production system for monoterpene esters. The invention also provides kits comprising the alcohol acyltransferase of the invention, the nucleic acid of the invention, the vector or gene construct of the invention, the host cell of the invention, or the transgenic non-human organism of the invention, and optionally at least one monoterpene alcohol, preferably a tertiary monoterpene alcohol.Finally, the present invention relates to a method for the production of fuel and / or biolubricant compounds, the method comprising: a) producing one or more monoterpene esters by any one of the methods of the present invention; b) optionally purifying the one or more monoterpene esters produced in step a); and c) converting some or all of the one or more monoterpene esters of step a) or the purified one or more monoterpene esters of step b) into a suitable product, preferably: tetrahydrolinalool; 2,6-dimethyloctane (DMO); saturated C20 hydrocarbon dimers; saturated C30 hydrocarbon trimers; hydrogenated methylcyclopentadiene dimers; and hydrogenated C40+ oligomers suitable for producing a biolubricant additive; and d) optionally combining the one or more fuel or biolubricant compounds with additional compounds suitable for fuels and / or biolubricants; wherein the fuel and / or biolubricant composition has, in total, from 0.01% (w / w) to 99.99% (w / w) of the fuel or biolubricant compound produced from one or more monoterpene esters obtainable by one of the methods of the present invention.

The invention discloses a method for increasing the yield of monoterpene glycoside in an endophytic fungus fermentation product separated from paeonia lactiflora, and relates to the technical field of plant fermentation. The method comprises the following steps: material treatment; separating strains; identifying strains; preparing a strain and an elicitor: drying and crushing the overground part of the Chinese herbaceous peony by using the endophytic fungus ER6 separated and identified in the step S3, and sieving with a 80-mesh sieve to prepare powder as a key elicitor; a potato glucose liquid culture medium is used as a basic fermentation culture medium, an activated ER6 strain is inoculated into a fermentation container filled with a sterilized PDB culture medium, and dry powder of the overground part of paeonia lactiflora is added into the culture medium to serve as a biological elicitor to be cultured in a shaking table; and harvesting fermentation liquor. According to the method, a specific endophytic fungus ER6 is separated from paeonia lactiflora roots, and it is found that the yield of monoterpene glycoside in a fermentation product can be remarkably increased by using the overground part of paeonia lactiflora as a biological elicitor to ferment the endophytic fungus ER6.

To provide a perfume composition which improves the delivery of perfume.SOLUTION: There is provided a perfume composition which comprises a monoterpene-based compound 1 represented by the formula (1) and a monoterpene-based compound 2 represented by the formula (2), wherein the compound 1 is a perfume. ((Rf1 and Rs1 are a substituent independently selected from the group consisting of a hydroxyl group, an ester group and a carbonyl group, both of which are substituents different from each other, Rf2 and Rs2 are the same substituent, Rf3 and Rs3 are the same substituent, Rf4 and Rs4 are the same substituent, Rf5 and Rs5 are the same substituent.)SELECTED DRAWING: None

Provided are a Blumea balsamifera monoterpene synthase BbTPS3 and related biological materials thereof and use thereof. BbTPS3 is: A1) a protein having the amino acid sequence shown in SEQ ID NO: 2; A2) a fusion protein obtained by linking protein-tags at the N-terminus or / and the C-terminus of the protein shown in SEQ ID NO: 2; and A3) a protein having at least 90% identity and the same function as the protein shown in A1), which is obtained by performing substitution and / or deletion and / or addition of one or more amino acid residues on the amino acid sequence shown in SEQ ID NO: 2. BbTPS3 can catalyze GPP to form l-borneol, and can be used to regulate and produce plant monoterpene compounds and cultivate Blumea balsamifera (L.) DC.

The present invention relates to a water-absorbing resin and a method for manufacturing the same. The method for manufacturing the same is to perform a polymerization reaction on an acid group-containing monomer using a specific amount of a foaming agent under pressure sealing to obtain a core layer having a specific surface porosity, and then perform a surface cross-linking reaction on the core layer using an acyclic monoterpene alcohol having a carbon number of 10 to 12 and a surface cross-linking agent, so that the water-absorbing resin obtained has both good water-absorbing properties and superior deodorizing efficacy.

The application belongs to the technical field of biology, and discloses application of CmPHL1 transcription factor in inhibition of citrus leaf oil cell formation and regulation of volatile substances. In view of the problem of insufficient research on existing citrus oil cell formation and essential oil synthesis, a pGBI-CmPHL1 overexpression vector is constructed, and positive strains are obtained by means of Agrobacterium-mediated transformation of citrus. Experiments prove that overexpression of CmPHL1 can significantly reduce the number of oil cells and the content of monoterpenes, sesquiterpenes and other volatile substances. CmPHL1 targets the molecular regulation network of oil cell development, accurately regulates and is heritable, provides a new gene target for citrus quality improvement and breeding, is in line with the direction of green agriculture, and has important economic and ecological benefits.

Provided are a Cinnamomum burmannii monoterpene synthase CbTPS1, an amino acid sequence thereof, a nucleic acid molecule encoding the protein, an use thereof in preparing the monoterpene synthase, and a method for preparing dextrorotatory borneol by using the Cinnamomum burmannii monoterpene synthase CbTPS1.

To provide a dentifrice composition which has a low water content and contains menthol and sorbitol at a specific mass ratio, while exhibiting excellent discharge properties from a container and offering a favorable flavor sensation.SOLUTION: A dentifrice composition comprises the following components (A) to (D): (A) menthol, (B) a fragrance component including a monoterpene compound (b1) other than component (A), (C) sorbitol, and (D) water in an amount of 10 mass% or more and 20 mass% or less, wherein the mass ratio of content of component (C) to content of component (A) ((C) / (A)) is 20 or more and 50 or less.SELECTED DRAWING: None

The invention discloses a eucalyptol synthase gene, a recombinant saccharomyces cerevisiae, and a construction method and application thereof. The construction method of the recombinant saccharomyces cerevisiae comprises: introducing a gene encoding a monoterpene synthase whose amino acid sequence is shown in SEQ ID No. 10, 11, 12 or 13 into saccharomyces cerevisiae to obtain a recombinant saccharomyces cerevisiae producing eucalyptol. The invention provides a powerful strain and a research basis for the biosynthesis of monoterpenes, and has important significance for the excavation of highly active monoterpene synthases.

Described herein are modified monoterpene TRPM8 activating compounds. In particular, provided herein are compounds that affect intracellular ion channel function, and are useful as or in conjunction with therapeutic agents. The compounds provided herein are useful in the treatment of a variety of diseases and disorders, including inflammatory eye diseases (e.g., uveitis), cardiovascular diseases, inflammatory diseases, and diseases characterized by aberrant hyperplasia (e.g., cancer).

This invention discloses a mango terpene synthase gene TPS4 and its applications, the nucleotide sequence of which is shown in SEQ ID NO:1. The amino acid sequence of the protein it encodes is shown in SEQ ID NO:2. The invention also discloses a recombinant expression vector containing the mango terpene synthase gene TPS4, a recombinant engineered strain, and the recombinant mango terpene synthase TPS4; and the application of the mango terpene synthase gene TPS4, its encoded protein, the recombinant expression vector, the recombinant engineered strain, or the recombinant TPS4 in regulating the synthesis of terpenoid compounds from geraniol diphosphate (GPP), neroli diphosphate (NPP), and farnesyl diphosphate (FPP). This invention is the first to clone and verify a terpene synthase gene TPS4 from the Sacred Heart mango genome, capable of simultaneously catalyzing the synthesis of monoterpenes and sesquiterpenes from three substrates: GPP, NPP, and FPP. It has broad application prospects and significant economic value.

Proposed are preparations comprising (i) a mixture of substances comprising (a) one, two or more compounds selected from the group consisting of (a1) alcohol monoterpenes of the formula (I) where R1 is H or methyl, R2 is H or C2-alkenyl, and R3 is a linear or branched, saturated or unsaturated hydrocarbon radical having 4 to 10 carbon atoms, and their enantiomers, diastereomers, racemates, solvates and physiologically acceptable salts, and / or (a2) bicyclic epoxy monoterpenes, (b) at least two lactones of the formula (II) where R4 is H or methyl, R5 is a linear or branched, saturated or unsaturated hydrocarbon radical having 2 to 10 carbon atoms and n is the number 1 or 2, and their enantiomers, diastereomers and racemates, and (c) one, two or more Solvent selected from the group consisting of ethanol, water, dipropylene glycol (DPG), diethyl phthalate (DEP), propylene glycol (PG),Isopropyl myristate (IPM), isopropyl palmitate (IPP), triethyl citrate (TEC), triacetin (TRI), 1,2-propanediol, 1,3-propanediol, propanetriol, pentanediol, hexanediol, octanediol, decanediol, dodecanol, 4-hydroxyacetophenone, butylene glycol, pentylene glycol, hexylene glycol, decylene glycol, propylene carbonate, butylene carbonate, glycerol carbonate, 2-benzylheptanol, trimethyl hydroxypentyl isobutyrate, glyceryl caprylate, ethylhexylglycerin, benzyl benzoate (BB), and optionally (d) further flavorings or fragrances selected from the group consisting of 3-phenylbutanal, acetylmethylcarbinol, anethole, anisyl acetate, dihydroeugenol, linalyl formate, 2-methyldecanal, 2-Benzyl-2-methylbut-3-ene nitrile, 3-hexenyl acetate, styralyl acetate, citronellal, cinnamyl acetate, rhubafuran, betalonone, anther, prenyl acetate, 2-phenylpropanal, 4-(4-hydroxyphenyl)butan-2-one, ethylphenoxyacetate, isoraldein, gamma-terpinene, Limonene, Neocyclocitral, Methyl Lavender Ketone, Styralyl Propionate, Phenyl Ethyl Propionate, Limonenal,4-Isopentylcyclohexanol, 4-methyl-2-phenyl-3,6-dihydro-2H-pyran / 4-methylene-2-phenyl-tetrahydropyran, hydrocitronitrile, phenoxanol, isoamylphenyl acetate, damascone, silvial, nectaryl, ambroxide, acetylpyrazine, trimethylpyrazine, isoamyl acetate, cresyl methyl ether para, filbertone, cyclohexyl acetate, heliotropin, acetophenone, anisaldehyde, methylacetophenone para, veratraldehyde, methyl anisate and vertoprenal, and (ii) aldehydes of the formula (III) where R6 is a saturated or unsaturated, linear hydrocarbon radical, and / or (iii) free fatty acids of the formula (IV) where R7 is a linear or branched, saturated hydrocarbon radical.

To provide a deodorizing composition capable of achieving both reduction of malodor in recycled resin and suppression of deterioration in physical properties of the recycled resin.SOLUTION: A deodorizing composition for deodorizing malodor of recycled resin comprises, as component (A), fragrance components (a-1) and (a-2), wherein a mass ratio of component (a-1) to a total amount of component (A) [component (a-1) / (total amount of component (A))] is 0.2 or more, and a mass ratio of component (a-2) to component (a-1) [component (a-2) / component (a-1)] is 3.5 or less: (a-1) monoterpene alcohols; and (a-2) ketones having one or more cyclic structures selected from 5-membered or 6-membered rings and having 10 to 16 carbon atoms.SELECTED DRAWING: None

To provide a novel volatile sulfur compound generation inhibitor and an agent volatilization device housing the same.SOLUTION: The present invention provides a volatile sulfur compound generation inhibitor containing at least one compound selected from monoterpenes (excluding those containing aldehyde groups), specific aliphatic ester compounds, specific aromatic ester compounds, specific aliphatic aldehyde compounds, specific aromatic aldehyde compounds, specific aliphatic alcohol compounds, specific aromatic alcohol compounds, specific ketone compounds, specific alicyclic compounds, specific aromatic compounds, and specific nitrogen-containing aliphatic compounds as an active ingredient.SELECTED DRAWING: None

Application of total monoterpene glycosides of Paeonia veitchii Lynch and analysis method for active ingredients in total monoterpene glycosides of Paeonia veitchii Lynch. For the first time, the UPLC-MS / MS technology is adopted in the present invention to establish the fingerprint of total monoterpene glycosides of Paeonia veitchii Lynch from 11 batches of different producing areas, laying a foundation for revealing the effective ingredient group of total monoterpene glycosides of Paeonia veitchii Lynch. Five compounds with muscle-building effects mainly composed of total monoterpene glycosides of Paeonia veitchii Lynch are determined in the present invention, including 4 monoterpene glycoside compounds, and one belongs to the isomer of benzoylpaeoniflorin. Application of total monoterpene glycosides of Paeonia veitchii Lynch in preparing animal feed or medicine for increasing muscle. The present invention establishes a fingerprint-pharmacodynamic correlation model of total monoterpene glycosides of Paeonia veitchii Lynch. While establishing the quality evaluation standard for muscle-building effects based on the fingerprint of the effective part of total monoterpene glycosides of Paeonia veitchii Lynch, it also provides a new idea for screening active ingredients of other pharmacological effects of Paeonia veitchii Lynch. The present invention lays a theoretical foundation for the development of muscle-building foods for fitness people and provides new resources for the development of animal feed additives in animal husbandry.

The invention provides functions and application research of a transcription factor HSFA4a, and discloses a novel gene HSFA4a closely related to regulation and control of phytoalexin, volatile monoterpene and sesquiterpene of plants. HSFA4a is not only subjected to constitutive regulation and control of PGF, but also induced by infection of plant diseases and insect pests. The invention provides a new action target for improving the insect resistance of plants.

The invention relates to the technical field of chemical analysis, in particular to an intelligent evaluation method for emission flux of organic matters in air, which comprises the following steps: obtaining an isolation coefficient of each time period in a relative abundance sequence according to the difference between data in each class cluster and data in each time period; correcting the initial screening parameter of each time period according to the difference between the isolation coefficients of all time periods of the relative abundance sequence to obtain the corrected screening parameter of each time period; according to the corrected screening parameters in each time period, the artificial monoterpene concentration of each collection device at each moment is obtained; and performing flux evaluation of artificial monoterpene emission according to the artificial monoterpene concentration of each collection device at each moment. According to the method, the accuracy of prediction of the discharge amount of the artificial monoterpene is improved, and the accuracy of flux evaluation of the artificial monoterpene is improved.

The present invention relates to a polymer, containing a structural unit A′ derived from a monomer A and a moiety B′ derived from a compound B, wherein monomer A contains a nitrogen atom and a polymerizable carbon-carbon double bond, and compound B is selected from a group consisting of bicyclic monoterpenes, monocyclic monoterpenes, acyclic monoterpenes, and C1-10 alkyl-substituted phenol, wherein the bicyclic monoterpene is selected from pinene-based compounds containing hydroxy, carene-based compounds containing hydroxy, chrysanthanol, and fenchol. The present invention further relates to processes of preparing the polymer.

Methods and systems for extracting additional beneficial lipid-soluble heavy compounds from plant material in an environmentally sustainable manner. A method includes preparing a solution that includes a solvent comprising one or more of a monoterpene, a monoterpenoid, a sesquiterpene, or a sesquiterpenoid. The solution further includes a solute comprising a plant material. The method includes extracting one or more compounds from the plant material using the solvent comprising the one or more of the monoterpene, the monoterpenoid, the sesquiterpene, or the sesquiterpenoid.