320 results about "Monoterpene" patented technology

The present invention refers to a composition based on monoterpenes with chemopreventive and chemotherapeutic effects in malignant neoplasias of humans and animals containing from 0,03% to 30% of monoterpenes and 99,97% of solvents. Another objective of the present invention is an application of monoterpenes in inhibition of cell growth and metastasis control of primary tumors being applied in vitro and in vivo gliomas cell lines C6 and U 87 and A172. Further another objective of the present invention refers to a specific methods for applying the composition with chemopreventive and chemotherapeutic effects in humans and animals showing malignant neoplasias by inhalation and nebulization treatment, oral and intratumoral, followed or not by radiotherapy with dilutions from 0,03% to 30% of the monoterpene perillyl or its derived metabolites diluted in the solvents specified by the usual techniques.

The invention provides methods for the inhibition of inflammation by providing, to a cell, in need thereof, monoterpene compositions that inhibit NF-κB. These compositions may also contain a carrier moiety that renders the monoterpene composition membrane permeable. The carrier may include triterpenoid moieties, sugars, lipids, or even additional monoterpenoid moieties. The composition can also contain additional chemical functionalities. Methods for using these compounds to prevent and treat a wide range of inflammatory conditions, especially, premalignant inflammatory conditions are described.

cis-Jasmone has been discovered to be useful as a semiochemical that changes the behaviour of insects and / or the physiology of plants. It has direct signalling roles with plant-feeding aphids, in attraction of aphid predators and parasitoids, and may act as an airborne signal inducing production of volatile plant semiochemicals, including the monoterpene (E)-β-ocimene, that stimulate foraging by parasitoids. It is an extremely benign compound having, to human beings, a pleasant aroma and gives a long-lasting effect after removal of the stimulus.

The present invention is directed to compositions and methods of delivery of CoQ that is reduced in the presence of lipoic acid and, optionally a fatty acid and / or optionally in a monoterpene. The compositions that include the reduced CoQ can be formulated in soft gel capsules.

The invention provides novel saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.

A method of sensitizing tumor cells to radiation thereapy, chemotherapy and immunomodulatory thereapy, comprising the step of exposing the tumor cell to an effective amount of at least one monoterpene or sesquiterpene and treating the tumor cell is disclosed.

A method of sensitizing tumor cells to radiation thereapy, chemotherapy and immunomodulatory thereapy, comprising the step of exposing the tumor cell to an effective amount of at least one monoterpene or sesquiterpene and treating the tumor cell is disclosed.

The present invention is directed to compositions and methods of delivery of CoQ-10 and an amino acid solubilized in monoterpenes. Use of monoterpenes as dissolving agents, greatly effects the ability to incorporate greater amounts of bioactive CoQ-10 and the amino acid, such as carnitine, i.e., carnitine tartrate, in formulations, such as soft gel capsules.

The present invention relates to pharmaceutical compositions and methods for the mucosal and oral administration of monoterpenes and derivatives thereof. The compositions of this invention further comprise one or more surfactants and cosolvents and are in the form of self-emulsifying compositions. The compositions of the invention may further comprise water-insoluble therapeutic agents, vaccines and diagnostics. Such agents include but are not limited to taxanes, steroids, topoisomerase inhibitors such as etoposide and other water-insoluble or lipophilic drugs.

Aqueous hard surface cleaner compositions useful for removing permanent ink are disclosed. The compositions comprise 75 to 99 wt. % of water; 0.1 to 5 wt. % of a monoterpene; 0.1 to 5 wt. % of a C10-C17 fatty acid derivative; and 0.1 to 5 wt. % of one or more surfactants. The fatty acid derivative is selected from N,N-dialkyl amides, N,N-dialkyl esteramines, and N,N-dialkyl amidoamines. Preferably, a base such as sodium carbonate or monoethanolamine is also included. The invention includes concentrates comprising the non-aqueous components recited above, as well as other applications for the cleaners and concentrates such as graffiti removers and permanent ink erasers. The combination of a monoterpene and certain fatty acid derivatives, especially fatty N,N-dialkyl amides, unexpectedly enables even dilute aqueous compositions to rapidly decolorize black permanent marker from hard, non-porous surfaces.

The invention relates to modified rosin resin and discloses modified rosin tackifying resin as well as a preparation method and application thereof. The preparation method comprises the following steps of: uniformly mixing rosin or rosin derivatives, monoterpene compounds, dicyclopentadiene fractions and catalysts in an autoclave; replacing air in the autoclave by use of nitrogen or carbon dioxide; reacting the mixture at a pressure of 0.2-0.6 Mpa and at 170-290 DEG C for 1 hour to 30 hours; and decompressing after the reaction, and removing low-boiling-point substances, thus obtaining the modified rosin tackifying resin, or adding an antioxidant stabilizer into the mixture at 200-230 DEG C, thus obtaining the modified rosin tackifying resin with higher quality. The softening point of the modified rosin tackifying resin ranges from 80 DEG C to 110 DEG C, the acid value of the tackifying resin is 15-70mg KOH per gram, and the color of the tackifying resin is less than No.6 Ghana color. The modified rosin tackifying resin can be widely applied to the field of tackifiers, coating paint, printing ink and the like, and especially can be applied to the field of metallocene catalysis polyolefin tackifiers.

The invention consists in modifying the levels of accumulation and emission of monoterpenes and sesquiterpenes in citrus as a mechanism to achieve systemic resistance against pathogens or repellency against pests. The alteration of the content of d-limonene and other terpenes is achieved by genetic transformation via the introduction of a gene that encodes an enzyme with d-limonene synthase activity, from a citrus fruit or plant or from another living organism, in antisense or RNAi (RNA interference) configuration. Genetic modification is achieved either by Agrobacterium tumefaciens or any other method of genetic transformation of plants from protoplasts or explants. The construction is incorporated in citrus genotypes or related genera of the family Rutaceae in order to reduce the levels of accumulation and emission of the monoterpene and precursor compounds and / or derivatives, either of leaves or flowers and / or fruit.

The present invention provides for a derivative of monoterpene or sesquiterpene, such as a perillyl alcohol derivative. For example, the perillyl alcohol derivative may be a perillyl alcohol carbamate. The perillyl alcohol derivative may be perillyl alcohol conjugated with a therapeutic agent such as a chemotherapeutic agent. The present invention also provides for a method of treating a disease such as cancer, comprising the step of delivering to a patient a therapeutically effective amount of a derivative of monoterpene (or sesquiterpene). The route of administration may vary, and can include, inhalation, intranasal, oral, transdermal, intravenous, subcutaneous or intramuscular injection.

The present invention relates to a composition derived from an essential oil obtained from one or more plants of the Melaleuca family in which at least 80% of the monoterpene content of the oil has been removed. The present invention also relates to a number of applications of the composition including antimicrobial, antiviral and therapeutic applications. The present invention in a particular embodiment relates to medical devices to which the composition has been applied and / or absorbed thereon.

The present invention is directed to compositions and methods of delivery of CoQ-10 and an amino acid solubilized in monoterpenes. Use of monoterpenes as dissolving agents, greatly effects the ability to incorporate greater amounts of bioactive CoQ-10 and the amino acid, such as carnitine, i.e., carnitine tartrate, in formulations, such as soft gel capsules.

This invention provides a compositions for transport of a therapeutic agent. The compositions contain a therapeutic agent and a monoterpene or an analog thereof. In one aspect, the monoterpene is perillyl alcohol (POH) or an analog thereof. In one aspect, the therapeutic agent is provided in an amount effective to treat the disease or subject of choice.

The presently claimed invention is directed to agricultural compositions which find primary use as a herbicide, through may also be used for pesticidal and fungicidal roles. The presently claimed invention comprises compositions combining monterpene compounds with fatty acid soaps. In particular monterpene alcohols are preferred as a primary phytoactive agent. Preferred embodiments are based on coniferous oils, such as pine oil, in combination with a tall oil reacted with an alkali to form a fatty acid soap. Preferred methods of application include spraying in a manner in which some foaming effect is observed, which appears to confer advantage over the spray application of monoterpene compounds alone.

Single-phase microemulsions, comprising a solvent, a surfactant blend and a carrier fluid, are effective spacer fluids for use during cementing operations. The solvent may be selected from the group consisting of monoterpenes, diterpenes, and alkyl or aryl esters of short-chain alcohols. The surfactant blend comprises a water-wetting surfactant or nonionic surfactant, a co-surfactant and an oil-solubilizing surfactant. The carrier fluid is aqueous. The solvent and surfactant blend are combined with the carrier fluid to produce the well-treatment microemulsion.

Compositions and solvent mixtures include at least one organic solvent and at least one terpene. In some embodiments, the terpene is a monoterpene. In some embodiments, the terpene is pure gum turpentine, oil of turpentine, a component of turpentine, or a combination of these. In some embodiments, the organic solvent is acetone or a green solvent. Addition of a minimal amount of terpene to the organic solvent or organic solution raises the flash point of the mixture, preferably to a predetermined value. The predetermined value is preferably in the range of 110 to 120° F. The amount of terpene is preferably in the range about 0.05 to about 5 percent by total weight of the mixture. In some embodiments, the compositions are used as coatings, such as paints or adhesives. In some embodiments, at least one terpene is added to a lubrication formulation.

Methods and compositions for improving the production of ethanol by a microorganism in a fermentation medium are provided, where the method comprises adding to the fermentation medium an emulsion comprising a monoterpene and a surfactant in an amount sufficient to improve the production of ethanol.

This invention provides a compositions for transport of a therapeutic agent. The compositions contain a therapeutic agent and a monoterpene or an analog thereof. In one aspect, the monoterpene is perillyl alcohol (POH) or an analog thereof. In one aspect, the therapeutic agent is provided in an amount effective to treat the disease or subject of choice.

Oil sands and like host materials are leached with a selected leachant to render pumpable the oil (including heavy oil, bitumen or kerogen and asphaltenes) as leachate. In a preferred embodiment, natural deposits are in situ leached and the leachate recovered and removed for treatment. The leachant is separated and recycled. The leachant is selected to be biodegradable and to not precipate asphaltenes, and to comprise monoterpenes of the formula C10H16. The overall process allows environmentally acceptable resource development and contaminated site remediation.

The invention discloses a bactericide composition containing propiconazole, flusilazole and levo-alpha-terpineol and a production method thereof, and the bactericide composition comprises the following active ingredients by weight percent: 1%-50% of propiconazole, 1%-50% of flusilazole, 1%-50% of levo-alpha-terpineol and the balance of auxiliaries. The formulation can be missible oil, microemulsion and emulsion in water. The bactericidal spectrum is expanded after complex of the composition, the bactericide composition further has obvious synergy, the usage amount and the using times of the bactericide can be significantly reduced, the cost is reduced, and the emergence of drug resistance to diseases can be also delayed. The bactericide composition can be used for control of banana leaf spot disease, banana scab, venturia pirina, peanut leaf spot disease, apple anthracnose and grape anthracnose. Simultaneously, the levo-terpineol has low toxicity and is easy for degradation as a monoterpene alcohol synthesized by a plant renewable resource-turpentine, thereby being in line with requirements on green and environmental protection. The micro-emulsion and the aqueous emulsion in the invention, wherein, the water part can replace an organic solvent,, thereby reducing the environmental pollution.