The invention discloses compound
essential oil for improving sleep as well as a preparation method and application of the compound
essential oil. The compound
essential oil is prepared from rhizoma nardostachyos,
frankincense,
schisandra chinensis,
neroli,
angelica sinensis and
rhodiola rosea essential oil according to a
specific volume ratio, preferably 9: 1.5: 11.25: 4.5: 1.5: 7.5. The traditional Chinese and
western medicine theories are fused in the formula, and the sleep improvement effect is achieved through multi-target cooperation. Animal experiment results show that the compound essential
oil can significantly prolong the pentobarbital
sodium induced
sleep time of mice, significantly improve the subthreshold
dose sleep rate and significantly shorten the sleep latency period of
phenobarbital sodium, does not affect the
weight gain of the mice after being continuously administered for 30 days, and has excellent
efficacy and good safety. Systematic'component missing 'and'proportion over-limit' contrast experiments prove that the six components are indispensable, and the optimal effect can be achieved only when the dosage of each component is strictly limited in the range of the composition, so that an experimental basis is provided for verifying the creativity of the composition.