The invention discloses a continuous hydrogenation rectification preparation method of 4-dimethylamino-2, 2, 6, 6-tetramethylpiperidine, and the preparation method comprises the following steps: premixing: adding triacetonamine and one of solvents (
methanol,
ethanol, isopropanol and
phenethyl alcohol) into a premixing kettle according to a certain
mass ratio of 10: (1-5), starting stirring, and transferring a premixed solution to an intermediate
temporary storage tank for heat preservation; the method comprises the following steps: loading a certain amount of a catalyst in a
fixed bed reactor, purging the
fixed bed reactor with
nitrogen, metering by a flowmeter, respectively introducing into the
fixed bed reactor, transferring a hydrogenation liquid containing 4-dimethylamino-2, 2, 6, 6-tetramethylpiperidine into a rapid removal kettle to remove water, a
solvent and part of impurities in the hydrogenation liquid, and carrying out
solid-liquid separation to obtain the 4-dimethylamino-2, 2, 6, 6-tetramethylpiperidine. According to the process preparation method,
continuous flow reaction purification is carried out, the product is stable in property and higher in yield, the product is continuously pumped into the front rectifying
tower to remove light component impurities, and then the material at the bottom of the front rectifying
tower is pumped into the rear rectifying
tower to remove heavy component impurities.