27 results about "Ethyl oleate" patented technology

Disclosed in the present invention are a refining device for medicinal ethyl oleate and a use method therefor. The refining device comprises a preset negative pressure vacuum batching apparatus, a vacuum pump, a dynamically adjustable memory reaction kettle, a discharge three-way pipe, a plate-frame circulating filtration assembly, a bag-type filter, a preset negative pressure vacuum finished product storage tank, a second centrifugal pump, and a barrel-type cartridge filter. The preset negative pressure vacuum batching apparatus is in communication with the dynamically adjustable memory reaction kettle; the discharge three-way pipe is disposed at a lower end of the dynamically adjustable memory reaction kettle; an input end of the plate-frame circulating filtration assembly and an input end of the bag-type filter are respectively in communication with and arranged at the other two ends of the discharge three-way pipe; the preset negative pressure vacuum finished product storage tank is in communication with and arranged at an output end of the bag-type filter. The present invention pertains to the field of ethyl oleate production, and specifically provides a refining device for medicinal ethyl oleate and a use method therefor, which overcomes the inability of existing ethyl oleate refining devices to control the peroxide value physicochemical index of the product, and facilitates more uniform and thorough stirring and mixing of materials.

The invention provides a nomeline nasal-brain delivery preparation for transnasal region mucosa administration, and an auxiliary material mixture of the nasal-brain delivery preparation comprises 1) phospholipid, and 2) any one of diluent ethyl oleate, isopropyl myristate, sesame oil or castor oil; optionally, the auxiliary material mixture can also comprise 3) a dissolving agent such as ethanol or diethylene glycol monoethyl ether, the auxiliary material mixture is a non-aqueous system, and a solution prepared from the mixture of the two or three auxiliary materials can be absorbed by the nasal meatus olfactory mucosa after being administrated through the nasal region mucosa, can be quickly conducted to the brain olfactory bulb region along olfactory nerves and cerebrospinal fluid, and can be used for treating the brain olfactory bulb. The problems that the peripheral side effect is high due to poor brain targeting of the medicine, the medicine takes effect slowly and the like are solved.

The invention discloses Leishan fish sauce sour essence as well as a preparation method and application thereof. The leishan fish sauce acid essence is prepared from ethyl acetate, absolute ethyl alcohol, ethyl isovalerate, ethyl hexanoate, isoamyl alcohol, furfuryl alcohol, ethyl lactate, ethyl caprylate, acetic acid, diethyl succinate, methyl salicylate, ethyl benzoate, ethyl laurate, hexanoic acid, phenethyl alcohol, 4-methyl guaiacol, ethyl myristate, ethyl palmitate, ethyl oleate, capsicum oleoresin, ethyl phenylacetate and ginger oil. And lactic acid, glycerol triacetate, ocimene, ethyl isovalerate, ethyl butyrate, anethole and phenylacetaldehyde. The Leishan fish sauce sour essence disclosed by the invention is soft and harmonious in overall fragrance, natural and vivid, still has stable flavor characteristics at high temperature, can make up the problem of flavor deficiency in sour soup products, realizes accurate reproduction and controllable release of composite fragrance, improves the standardization level of products, and effectively improves the preference degree of consumers.

The invention relates to the technical field of pharmaceutical analysis, and particularly discloses a method for simultaneously determining the content of benzyl alcohol and ethyl oleate. The method for simultaneously measuring the content of benzyl alcohol and ethyl oleate comprises the following steps: S1, mixing a sample to be measured with a low alcohol aqueous solution, freezing, adding non-polar straight-chain alkane, extracting and layering to obtain a liquid to be measured; s2, an Agilent DB-WAX chromatographic column is adopted and matched with optimized chromatographic conditions such as a heating procedure, gas chromatography detection is conducted on the to-be-detected liquid, and therefore simultaneous quantitative determination of benzyl alcohol and ethyl oleate is achieved. The method provided by the invention has the advantages of simplicity and convenience in operation, high accuracy, good repeatability, strong applicability and the like, and solves the problems of poor separation degree of benzyl alcohol and ethyl oleate and low detection efficiency in the prior art.

The present application relates to the technical field of liquor quality. The present application utilizes the same fungus Eurotium cristatum SXHBTBU1934 CGMCC NO.21026 as yeast to independently ferment wheat, and then utilizes the fermented wheat as "microbial filter material" to filter distilled liquor. The specific method for improving liquor quality by utilizing microbial fermentation material comprises the following steps: filtering liquor body by adsorption material to obtain filtered liquor body; mixing the filtered liquor body with washing-removing material to obtain washing-removed liquor body; and performing fine filtration on the washing-removed liquor body to obtain product liquor body. By utilizing the method of the present application, the compounds such as ethyl oleate and ethyl linoleate, which have negative influence on the flavor of liquor and have viscosity, can be reduced in the liquor body; meanwhile, the acid ester compounds such as ethyl octanoate are increased, which adds fruit flavor to the liquor body, but does not destroy the flavor balance of the four flavoring substances such as ethyl acetate, ethyl lactate, ethyl butyrate and ethyl hexanoate, and does not affect the main taste of the liquor body.

The utility model belongs to ethyl oleate preparation technical field especially one kind is provided with the preparation device of ethyl oleate of adsorption function, it includes reation kettle equipment and adsorption box, the top of adsorption box is provided with feeding opening, and the bottom end fixed communication of reation kettle equipment has liquid outlet pipe, and this preparation device still includes: connecting pipe, the bottom end fixed communication of connecting pipe is on liquid outlet pipe, and the top end fixed communication of connecting pipe is in the top of adsorption box, and water pump is fixedly installed on connecting pipe, infusion tube, the top fixed communication of infusion tube is on the bottom end of adsorption box, and valve is fixedly installed on infusion tube, the utility model discloses through simple structure has realized to ethyl oleate after esterification reaction, can efficiently remove the impurity and moisture in ethyl oleate inside, avoids the influence of ethyl oleate preparation after color, smell and purity, improves the finished product quality of ethyl oleate, and the practicality is strong.

The application belongs to the technical field of fermentation engineering, and relates to application of ethyl linoleate in improving nystatin yield and a fermentation method for high-yield nystatin. The application provides the application of ethyl linoleate in improving the nystatin yield. By using ethyl linoleate as a feed, the yield of nystatin in the process of fermentative production of nystatin can be improved.

The present disclosure relates to compositions including a UV absorbing system including at least one physical ultraviolet (UV)-attenuating material and at least one oil for inhibiting physical ultraviolet (UV)-attenuating material aggregation, as well as to methods of making and using such compositions.

The application belongs to the field of biology and particularly relates to a propandiol-feeding Lactobacillus lentus capable of simultaneously producing 2-nonanol and ethyl oleate and application thereof. The preservation number of the propandiol-feeding Lactobacillus lentus is CGMCC No.25141. The strain can produce 2-nonanol and ethyl oleate with contents of 0.330 mg / L and 0.213 mg / L respectively, and thus can be applied to liquor brewing as a strengthening agent.

The invention discloses a digestion-aiding lactein tablet and a preparation method thereof, and belongs to the technical field of pharmaceutical preparations. The method comprises the following steps: firstly, mixing lactein, cane sugar, aspartame, milk-flavored essence and talcum powder, granulating, adding magnesium stearate, uniformly mixing, and pressing into tablet cores; then preparing a coating solution containing hydroxypropyl methylcellulose, Tween 80, amphiphilic nano lamellar magnesium-aluminum layered double hydroxides, amphiphilic mesoporous silica-zinc oxide hybrid particles, ethyl oleate and polyethylene glycol 400, and then preparing the coating solution containing hydroxypropyl methylcellulose, Tween 80, amphiphilic nano lamellar magnesium-aluminum layered double hydroxides, amphiphilic mesoporous silica-zinc oxide hybrid particles, ethyl oleate and polyethylene glycol 400; and finally, spraying the coating liquid on the surface of the tablet core to obtain a finished product. According to the method, two amphiphilic nano materials prepared by adopting a specific process are combined with coating components to form a coating layer with a specific function. The prepared lactein tablet can effectively protect the core component and improve the action effect of the core component in the intestinal tract, so that the better functions of helping digestion and regulating the intestinal flora are synergistically exerted.

The invention relates to a compound emulsion for preventing and controlling bovine viral diarrhea. Every 100 g of the compound emulsion comprises the following components by weight: 0.1 to 6.0 g of bovine viral diarrhea antibody, 2.0 to 4.0 g of solanum nigrum polysaccharide, 0.1 to 1.0 g of donaxine, 0.1 to 5.0 g of taurine, 1.0 to 3.0 g of ephedra oil, 4.0 to 10.0 g of polyoxyethylene (40) castor oil, 10.0 to 18.0 g of linoleic acid, 14.0 to 20.0 g of ethyl oleate, 15.0 to 25.0 g of span-40, and the balance of water for injection. Primary emulsion of the reemulsion is in an oil-in-water (O / W) type, and secondary emulsion of the reemulsion is in an oil-water mutual wrapping type. The invention further discloses a preparation method, the process controllability is high, and low-cost production is facilitated. The reemulsion can play a slow-release and long-acting role after intramuscular injection, the effective concentration of the antibody can be maintained in vivo for a long time, repeated medication is not needed, the stress reaction of animals is reduced, meanwhile, viruses are neutralized more thoroughly, the overall curative effect is remarkably improved, and the treatment cycle is shortened.

The invention discloses a self-curing injectable pectin hydrogel and a preparation method and application thereof.Based on 100 parts by weight of the hydrogel, the hydrogel is prepared from, by weight, 30-80 parts of Pickering emulsion, 0.5-5 parts of pectin and the balance water, based on 100 parts by weight of the Pickering emulsion, 0.5-5 parts of the pectin and the balance water, and based on 100 parts by weight of the Pickering emulsion, 0.5-5 parts of the pectin are added, the Pickering emulsion contains 2 to 20 parts by weight of pluronic F127 and 0.1 to 5 parts by weight of hydroxyapatite, and on the basis of 100 unit volume of the Pickering emulsion, the Pickering emulsion contains 20 to 70 unit volume of ethyl oleate. According to the hydrogel, hydroxyapatite nanoparticles are used as a hydrogel cross-linking agent and also used as a stabilizer for stabilizing a Pickering emulsion, and a biodegradable pectin substrate is combined, so that the effects of promoting bone repair and preventing tumor recurrence are achieved. The system can effectively promote apoptosis of osteosarcoma cells, inhibit migration of the osteosarcoma cells and regulate and control the cycle of the osteosarcoma cells in vitro, and shows a remarkable anti-osteosarcoma effect and an osteogenesis promotion effect in vivo.

The application belongs to the technical field of microbial fermentation, and particularly relates to an abnormal williamsonia yeast and application of the abnormal williamsonia yeast in preparation of ethyl palmitate, propyl linoleate or ethyl oleate. Wickerhamomyces anomalus The abnormal williamsonia yeast is abnormal williamsonia yeast Lz5, and is classified and named as abnormal williamsonia yeast Wickerhamomyces anomalus , which is preserved in the China General Microbiological Culture Collection Center on June 19, 2025, has a preservation number of CGMCC No.34954, and an address of the preservation unit is No.3, Institute of Microbiology, Chinese Academy of Sciences, 1, Beichen West Road, Chaoyang District, Beijing. Ethyl palmitate, propyl linoleate and ethyl oleate can be prepared by fermenting sugarcane juice with the abnormal williamsonia yeast. The content of ethyl palmitate in the culture medium after fermentation can reach 13.68 mg / L. After subsequent extraction, the abnormal williamsonia yeast can be used for industrial production.

The present application relates to the technical field of high polymer materials, and more particularly to a high-toughness composite recycled plastic and a preparation method thereof, which specifically comprises recycled polypropylene, KH550 modified TiO2 nanoparticles and surface-treated fly ash; the surface-treated fly ash is selected from one or more of isopropyl palmitate treated fly ash, furfuryl palmitate treated fly ash, ethyl myristate treated fly ash and ethyl oleate treated fly ash. On the basis of the prior art, the isopropyl palmitate, furfuryl palmitate, ethyl myristate and ethyl oleate are used to treat the fly ash and are compounded with the KH550-TiO2 nanoparticles, so as to further improve the mechanical properties of the recycled polypropylene. Meanwhile, the number of hydroxyl groups on the surface of the fly ash is further increased through acid treatment, the interfacial adhesion between the fly ash and the recycled polypropylene is improved, and the mechanical properties are further improved.

The present application relates to the technical field of pharmaceutical preparation, and discloses a tulobuterol transdermal patch and a preparation method thereof.The tulobuterol transdermal patch comprises a backing layer, a paste layer and an anti-sticking layer, the paste layer comprises tulobuterol, pressure-sensitive adhesive and a penetration enhancer, the pressure-sensitive adhesive is a copolymer of 2-ethylhexyl acrylate, butyl acrylate, tertiary octyl acrylamide and methyl methacrylate, and the penetration enhancer contains propylene glycol and ethyl oleate.The present application adopts a new pressure-sensitive adhesive matrix, solves the problem that tulobuterol is easy to crystallize out in the patch, and enhances the transdermal effect of tulobuterol by using a penetration enhancer.The present application also discloses a preparation method of the tulobuterol transdermal patch, and the preparation process is improved, so that the loss of tulobuterol in the preparation process is reduced, the quality of the medicine is improved, and the cost is reduced.

The invention relates to the technical field of pesticides, and particularly discloses an epoxiconazole-containing nanoscale bactericide and a preparation method thereof. The epoxiconazole-containing nanoscale bactericide is mainly prepared from the following raw materials in percentage by weight: 10 to 15 percent of epoxiconazole active compound, 1 to 3 percent of tripeptide-1 derivative, 0.3 to 0.7 percent of 1, 3-dimethyl-2-imidazolinone, 1 to 3 percent of sodium lauryl polyoxyethylene ether sulfate, 2 to 4 percent of sodium polyphosphate, 0.5 to 0.9 percent of thickening agent, 0.001 to 0.003 percent of preservative, 3 to 5 percent of antifreezing agent, 0.1 to 0.5 percent of organic silicon defoaming agent and the balance of water. The tripeptide-1 derivative is obtained by treating tripeptide-1 with ethyl oleate. The nanoscale bactericide has the characteristics of being high in epoxiconazole suspension rate, easy to pour and clean, good in storage stability, good in prevention and treatment effect and high in pesticide effect, and meets market requirements.

The invention discloses an absorption-promoting multi-element composite collagen composition and a preparation method thereof, and belongs to the field of cosmetic raw materials, the absorption-promoting multi-element composite collagen composition comprises the following components by mass: 5%-15% of multi-element composite collagen, 0.1%-0.5% of sodium hyaluronate, 3%-7% of ethyl oleate, 2%-5% of azone, citric acid for maintaining pH at 5.5-6.5, and the balance of water, the multi-element composite collagen comprises I type collagen, III type collagen and XVII type collagen. The azone mainly destroys ordered arrangement of cuticle lipid, the ethyl oleate can further dissolve lipid, the combination of the azone and the ethyl oleate can more effectively weaken the barrier effect of skin barrier and promote collagen penetration, and the sodium hyaluronate increases the hydration degree of the cuticle and makes the cuticle swell, so that the compactness of the skin is reduced, and the skin care effect is improved. And a more favorable condition is provided for penetration of the collagen. The formula has good safety and stability, and is suitable for various skin types.

The invention provides a method for preparing human milk substitute fat through multi-step enzyme catalysis transesterification reaction. The method comprises the following steps: catalyzing grease rich in palmitic acid with ethyl oleate and ethyl linoleate by adopting an enzyme to carry out transesterification reaction, after the reaction is finished, crystallizing and separating materials under different low-temperature conditions, and separating out a liquid phase rich in OPO / OPL; the separated solid phase is continuously subjected to an enzyme catalysis reaction until the yield of the product OPO / OPL reaches 90% or above. Compared with a one-step method, the method for preparing human milk substitute fat OPO / OPL based on molecular distillation or acid-base neutralization or adopting a surfactant and solvent fractionation and other traditional two-step or multi-step enzyme method technologies, the method for preparing human milk substitute fat OPO / OPL through multi-step enzyme catalysis transesterification reaction has the advantages of being low in raw material price, mild in reaction condition, free of acid-base use, free of organic solvent introduction, low in carbon and environment-friendly in the whole process, low in cost, easy to operate and the like. And the method has the advantages of simple process operation, easy industrial amplification and the like, and has good industrial application prospects.

The invention relates to the technical field of pharmaceutical preparations, and discloses a tulobuterol transdermal patch and a preparation method thereof. The tulobuterol transdermal patch comprises a backing layer, a paste layer and an anti-sticking layer, the paste layer comprises tulobuterol, a pressure-sensitive adhesive and a penetration enhancer, the pressure-sensitive adhesive is a copolymer of 2-ethylhexyl acrylate, butyl acrylate, tert-octyl acrylamide and methyl methacrylate, and the penetration enhancer contains propylene glycol and ethyl oleate. According to the tulobuterol transdermal patch, the novel pressure-sensitive adhesive matrix is adopted, the problem that tulobuterol is easy to separate out and crystallize in the patch is solved, and the transdermal effect of tulobuterol is enhanced by using the penetration enhancer. The invention also discloses a preparation method of the tulobuterol transdermal patch, through the improvement of the preparation process, the loss of tulobuterol in the preparation process is reduced, the medicine quality is improved, and meanwhile, the cost is reduced.

The invention discloses preparation and application of an arginine-octanoic acid ionic liquid microemulsion. The microemulsion system comprises a hydrophilic phase, a lipophilic phase and a mixed emulsifier, the hydrophilic phase is composed of arginine-caprylic acid ionic liquid and water, the lipophilic phase is ethyl oleate, and the mixed emulsifier is Span-20 and Tween-80. The emulsion comprises the following components in percentage by mass: 10%-60% of a hydrophilic phase, 5%-15% of an oleophylic phase and 35%-80% of an emulsifier. The ionic liquid microemulsion is mixed with bulk drugs to prepare a drug-loaded microemulsion preparation. The amino acid ionic liquid used in the invention has good biocompatibility, and can effectively adjust the viscosity of the system, increase the stability and promote the transdermal absorption of the drug.

The invention discloses a phenylbutazone peak shifting sustained release injection. Every 100 g of the phenylbutazone peak shifting sustained release injection is prepared from the following components by weight: 4.0 to 10.0 g of phenylbutazone, 3.0 to 9.0 g of polyethylene glycol 12000, 5.0 to 13.0 g of povidone C15, 8.0 to 18.0 g of ethyl oleate, 4.0 to 8.0 g of span 20, 1.0 to 3.0 g of behenic acid, 0.5 to 2.5 g of propylene glycol alginate, 0.1 to 2.0 g of propyl gallate and the balance of corn oil. The injection contains three kinds of phenylbutazone drug forms, the drug is released in different time periods after intramuscular injection, and the peak value of plasma concentration is staggered, so that the effect of staggered-peak release is realized. According to the technology, on one hand, the highest plasma concentration is reduced, the liver and kidney metabolism burden is remarkably relieved, and the safety is improved, on the other hand, the effective plasma concentration maintaining time is prolonged, the administration frequency is reduced, the stress reaction generated in the animal fixing process is reduced, and time and labor are saved. Meanwhile, the invention further discloses a preparation method, the process is easy to convert, and the application prospect is wide.

The invention discloses a method for detecting the content of active ingredients in magnolia wufengensis volatile oil, and belongs to the field of quality control of traditional Chinese medicines. A gas chromatograph is adopted to be equipped with a hydrogen flame ionization detector (GC-FID), a chromatographic column is Agilent VF-17 ms, carrier gas is helium, and the flow velocity is 0.8 mL / min; temperature programming; and carrying out quantitative analysis by adopting an external standard method. The GC method for simultaneously determining the content of the five active ingredients (beta-elemene, ethyl palmitate, ethyl linoleate, ethyl linolenate and squalene) in the magnolia wufengensis volatile oil is established for the first time, the method is economical, accurate and good in repeatability, and scientific basis and technical support are provided for quality control and standardized evaluation of the magnolia wufengensis volatile oil.

The invention provides an in-situ injection phase change gel sustained-release preparation as well as a preparation method and application thereof, and particularly relates to a stable injectable gel sustained-release preparation prepared from phospholipid, oil for injection and active pharmaceutical ingredients, the in-situ injection phase change gel sustained-release preparation comprises the following components in parts by weight: 10-60 parts of phospholipid, 45-90 parts of oil for injection and 0.0025-20 parts of active pharmaceutical ingredients; the oil for injection is selected from the combination of ethyl oleate and / or ethyl linoleate and medium-chain fatty glyceride, has the characteristics of good biocompatibility, remarkable slow-release effect, wide application range, simplicity in preparation and the like, and has a wide application prospect.

The invention discloses and provides a composition of iodinated ethyl oleate and iodinated ethyl linoleate, and the mass ratio of the iodinated ethyl oleate to the iodinated ethyl linoleate is (1.5-3.5): (8.5-6.5) according to the mass ratio of the iodinated ethyl oleate to the iodinated ethyl linoleate. The invention also discloses a preparation method and application of the composition of iodinated ethyl oleate and iodinated ethyl linoleate. The composition of iodinated ethyl oleate and iodinated ethyl linoleate is single in component, controllable in quality and consistent and stable in contrast effect when being used as a contrast agent.

The invention discloses a gel composition for cleaning capsaicin on a skin surface and application of the gel composition. The gel composition comprises an organic solvent, a surfactant, ethyl oleate, menthol, a gel matrix and water, the gel composition is used again after the capsaicin is applied to the skin surface for a proper time, so that the side effects generated by the capsaicin are reduced.

The application relates to the technical field of pesticides, and particularly discloses a nanoscale fungicide containing fluquinconazole and a preparation method thereof. The nanoscale fungicide containing fluquinconazole is mainly prepared from the following raw materials in percentage by weight: fluquinconazole 10-15%, tripeptide-1 derivative 1-3%, 1,3-dimethyl-2-imidazolidinone 0.3-0.7%, lauryl alcohol polyoxyethylene ether sulfate sodium salt 1-3%, polyphosphate sodium salt 2-4%, thickening agent 0.5-0.9%, preservative 0.001-0.003%, antifreezing agent 3-5%, organic silicon defoaming agent 0.1-0.5%, and water as the balance; the tripeptide-1 derivative is obtained by treating tripeptide-1 with ethyl oleate. The nanoscale fungicide has the characteristics of high fluquinconazole suspension rate, easy pouring, easy cleaning, good storage stability, good control effect and high efficacy, and meets the market demand.

The invention relates to the technical field of daily chemical cleaning products, and discloses a plant-derived silicone oil-free stainless steel hydrophobic polishing cleaning paste. Comprising the following components in parts by weight: 10-15 parts of modified bambusa vulgaris silicon powder, 4-6 parts of modified soybean phospholipid, 5-8 parts of soybean oil acid ethyl ester sodium sulfonate, 0.2-0.5 part of tea saponin, 2-5 parts of epoxy soybean oleic acid ethyl ester, 2-3 parts of aluminum stearate, 2-3 parts of oleyl borate, 1-2 parts of caprylic acid monoglyceride and 57.5-73.8 parts of deionized water. According to the plant-sourced silicone oil-free stainless steel hydrophobic polishing cleaning paste, an all-around cleaning and protecting system is constructed through precise matching and synergistic energizing of plant-sourced components, the dual targets of efficient decontamination and metal protection are achieved, the characteristics of all the components are complementary, and the plant-sourced core components have a good cleaning effect by means of excellent permeability and targeting effect. And meanwhile, dirt particles are captured and prevented from being attached again, and the surface has uniform and transparent texture after being cleaned.