40 results about "Ethyl oleate" patented technology

The invention discloses a compound traditional Chinese medicine patch for conditioning hyperplasia of mammary glands and a preparation method thereof, and relates to the technical field of traditional Chinese medicine preparations. The compound traditional Chinese medicine patch for conditioning hyperplasia of mammary glands is prepared from an iron-based metal organic framework composite drug carrying system, dopamine hydrochloride, a blank gel matrix, ethyl oleate, menthol, a solubilizer, a wetting agent and water, the iron-based metal organic framework composite drug loading system is composed of traditional Chinese medicine dihydric alcohol plastid, iron-based metal organic framework nanoparticles and cinnamomum camphora essential oil. The traditional Chinese medicine dihydric alcohol plastid and the cinnamomum camphora essential oil are loaded in the iron-based metal organic framework nano particles, so that the transdermal absorption of the medicine is improved, the pH response release property is realized, the dosage of active ingredients permeating into a focus part and the lasting action time are effectively increased, and then a coating layer is formed by polydopamine, so that the anti-inflammatory effect is improved. The dispersibility and compatibility of the drug loading system in vivo are further enhanced, the drug effect can be fully exerted, and the treatment effect on the hyperplasia of mammary glands is remarkably improved.

Disclosed in the present invention are a refining device for medicinal ethyl oleate and a use method therefor. The refining device comprises a preset negative pressure vacuum batching apparatus, a vacuum pump, a dynamically adjustable memory reaction kettle, a discharge three-way pipe, a plate-frame circulating filtration assembly, a bag-type filter, a preset negative pressure vacuum finished product storage tank, a second centrifugal pump, and a barrel-type cartridge filter. The preset negative pressure vacuum batching apparatus is in communication with the dynamically adjustable memory reaction kettle; the discharge three-way pipe is disposed at a lower end of the dynamically adjustable memory reaction kettle; an input end of the plate-frame circulating filtration assembly and an input end of the bag-type filter are respectively in communication with and arranged at the other two ends of the discharge three-way pipe; the preset negative pressure vacuum finished product storage tank is in communication with and arranged at an output end of the bag-type filter. The present invention pertains to the field of ethyl oleate production, and specifically provides a refining device for medicinal ethyl oleate and a use method therefor, which overcomes the inability of existing ethyl oleate refining devices to control the peroxide value physicochemical index of the product, and facilitates more uniform and thorough stirring and mixing of materials.

The invention provides a nomeline nasal-brain delivery preparation for transnasal region mucosa administration, and an auxiliary material mixture of the nasal-brain delivery preparation comprises 1) phospholipid, and 2) any one of diluent ethyl oleate, isopropyl myristate, sesame oil or castor oil; optionally, the auxiliary material mixture can also comprise 3) a dissolving agent such as ethanol or diethylene glycol monoethyl ether, the auxiliary material mixture is a non-aqueous system, and a solution prepared from the mixture of the two or three auxiliary materials can be absorbed by the nasal meatus olfactory mucosa after being administrated through the nasal region mucosa, can be quickly conducted to the brain olfactory bulb region along olfactory nerves and cerebrospinal fluid, and can be used for treating the brain olfactory bulb. The problems that the peripheral side effect is high due to poor brain targeting of the medicine, the medicine takes effect slowly and the like are solved.

The invention belongs to the technical field of microbial fermentation, and particularly relates to Wickerhamomyces anomalus and application thereof in preparation of ethyl palmitate, propyl linoleate or ethyl oleate. According to the present invention, the Wickerhamomyces anomalus is provided, the Wickerhamomyces anomalus is the Wickerhamomyces anomalus Lz5, the classification name of the Wickerhamomyces anomalus is Wickerhamomyces anomalus, the Wickerhamomyces anomalus is preserved in the China General Microbiological Culture Collection Center on June 19, 2025, and the preservation number of the Wickerhamomyces anomalus is CGMCC No. 34954; the address of the preservation unit is Institute of Microbiology, Chinese Academy of Sciences, No.3, No.1 Yard, Beichen West Road, Chaoyang District, Beijing; when the strain is used for fermenting sugarcane juice, ethyl palmitate, propyl linoleate and ethyl oleate can be prepared. In the culture medium after fermentation is finished, the content of ethyl palmitate can reach 13.68 mg / L. After subsequent extraction, the method can be used for industrial production.

The invention discloses Leishan fish sauce sour essence as well as a preparation method and application thereof. The leishan fish sauce acid essence is prepared from ethyl acetate, absolute ethyl alcohol, ethyl isovalerate, ethyl hexanoate, isoamyl alcohol, furfuryl alcohol, ethyl lactate, ethyl caprylate, acetic acid, diethyl succinate, methyl salicylate, ethyl benzoate, ethyl laurate, hexanoic acid, phenethyl alcohol, 4-methyl guaiacol, ethyl myristate, ethyl palmitate, ethyl oleate, capsicum oleoresin, ethyl phenylacetate and ginger oil. And lactic acid, glycerol triacetate, ocimene, ethyl isovalerate, ethyl butyrate, anethole and phenylacetaldehyde. The Leishan fish sauce sour essence disclosed by the invention is soft and harmonious in overall fragrance, natural and vivid, still has stable flavor characteristics at high temperature, can make up the problem of flavor deficiency in sour soup products, realizes accurate reproduction and controllable release of composite fragrance, improves the standardization level of products, and effectively improves the preference degree of consumers.

The invention provides a glabridin micro-emulsion, a glabridin micro-emulsion mask liquid and a preparation method, and relates to the technical field of cosmetics. The glabridin microemulsion provided by the invention is prepared from the following raw materials: glabridin, tween-80, 1, 2-hexanediol, ethyl oleate and water, and the mass ratio of the glabridin to the tween-80 to the 1, 2-hexanediol to the ethyl oleate to the water is (0.25 to 2.5) to (12.5 to 25) to (12.5 to 50) to (5 to 12.5) to 19. According to the glabridin microemulsion, 1, 2-hexanediol is used as a surfactant, tween-80 is used as a cosurfactant, ethyl oleate is used as an oil phase, glabridin is wrapped in the microemulsion, the solubility and skin permeability of glabridin can be improved, and cosmetics can efficiently play skin care functions such as whitening and relieving. The invention provides a glabridin micro-emulsion mask liquid which has good whitening, moisturizing and soothing effects.

The invention relates to the technical field of pharmaceutical analysis, and particularly discloses a method for simultaneously determining the content of benzyl alcohol and ethyl oleate. The method for simultaneously measuring the content of benzyl alcohol and ethyl oleate comprises the following steps: S1, mixing a sample to be measured with a low alcohol aqueous solution, freezing, adding non-polar straight-chain alkane, extracting and layering to obtain a liquid to be measured; s2, an Agilent DB-WAX chromatographic column is adopted and matched with optimized chromatographic conditions such as a heating procedure, gas chromatography detection is conducted on the to-be-detected liquid, and therefore simultaneous quantitative determination of benzyl alcohol and ethyl oleate is achieved. The method provided by the invention has the advantages of simplicity and convenience in operation, high accuracy, good repeatability, strong applicability and the like, and solves the problems of poor separation degree of benzyl alcohol and ethyl oleate and low detection efficiency in the prior art.

The present application relates to the technical field of liquor quality. The present application utilizes the same fungus Eurotium cristatum SXHBTBU1934 CGMCC NO.21026 as yeast to independently ferment wheat, and then utilizes the fermented wheat as "microbial filter material" to filter distilled liquor. The specific method for improving liquor quality by utilizing microbial fermentation material comprises the following steps: filtering liquor body by adsorption material to obtain filtered liquor body; mixing the filtered liquor body with washing-removing material to obtain washing-removed liquor body; and performing fine filtration on the washing-removed liquor body to obtain product liquor body. By utilizing the method of the present application, the compounds such as ethyl oleate and ethyl linoleate, which have negative influence on the flavor of liquor and have viscosity, can be reduced in the liquor body; meanwhile, the acid ester compounds such as ethyl octanoate are increased, which adds fruit flavor to the liquor body, but does not destroy the flavor balance of the four flavoring substances such as ethyl acetate, ethyl lactate, ethyl butyrate and ethyl hexanoate, and does not affect the main taste of the liquor body.

The utility model belongs to ethyl oleate preparation technical field especially one kind is provided with the preparation device of ethyl oleate of adsorption function, it includes reation kettle equipment and adsorption box, the top of adsorption box is provided with feeding opening, and the bottom end fixed communication of reation kettle equipment has liquid outlet pipe, and this preparation device still includes: connecting pipe, the bottom end fixed communication of connecting pipe is on liquid outlet pipe, and the top end fixed communication of connecting pipe is in the top of adsorption box, and water pump is fixedly installed on connecting pipe, infusion tube, the top fixed communication of infusion tube is on the bottom end of adsorption box, and valve is fixedly installed on infusion tube, the utility model discloses through simple structure has realized to ethyl oleate after esterification reaction, can efficiently remove the impurity and moisture in ethyl oleate inside, avoids the influence of ethyl oleate preparation after color, smell and purity, improves the finished product quality of ethyl oleate, and the practicality is strong.

The invention relates to the technical field of metal rolling and rolling oil, and provides anti-spot and anti-corrosion rolling oil as well as a preparation method and a use method of the anti-spot and anti-corrosion rolling oil. 9 to 13 parts of synthetic ester; 2 to 3 parts of an antioxidant; 5-8 parts of an anti-wear reagent at extreme pressure; 2-3 parts of an antirust agent; 4-5 parts of an emulsifier; 0.7 to 1.2 parts of a bulking agent and 0.007 to 0.012 part of a nanometer self-lubricating agent; the base oil is mineral oil 150SN, castor oil and 500SN base oil, and based on the total mass of the base oil, the ratio of the mineral oil 150SN to the castor oil to the 500SN base oil in the base oil is (1.7-1.9): 1: (0.1-0.2); the compatibilizer is isopropyl palmitate and ethyl oleate, and the ratio of isopropyl palmitate to ethyl oleate is (3.4-5.4): 1 based on the total mass of the compatibilizer; the nanometer self-lubricating agent comprises nanometer molybdenum disulfide and nanometer silicon dioxide, and the ratio of the nanometer molybdenum disulfide to the nanometer silicon dioxide is 1: (1.4-1.5) according to the total mass of the nanometer self-lubricating agent. And spots and corrosion of the silicon steel in the cold rolling process are avoided.

The invention provides a patch composition, a patch and a preparation method of the patch. The patch composition comprises the following components in parts by weight: 2-4 parts of a compound I or pharmaceutically acceptable salt thereof, 12-17 parts of ethyl oleate, 5-9 parts of isopropyl myristate, 1-5 parts of propylene glycol laurate, 2-10 parts of a crystal inhibitor, 0.01-0.5 part of an antioxidant and 66-81 parts of an acrylic pressure-sensitive adhesive. By compounding two crystal inhibitors of povidone and butylated hydroxytoluene, a patch composition and a patch of a compound I which can reduce or avoid drug crystallization, reduce cold flow, reduce irritation and have better stability are provided, and the effectiveness and safety of the drug are improved; the permeation performance of the compound I in the patch composition and the patch is enhanced by selecting the pressure-sensitive adhesive of a specific model, and the effectiveness of the medicine is improved.

The invention discloses a preparation method of a medicine for treating ovarian cancer and endometrial carcinoma and the medicine for treating the ovarian cancer and the endometrial carcinoma. The invention belongs to the technical field of medicine preparation, and aims to solve the problem of preparation of medicines for treating ovarian cancer and endometrial carcinoma, polyoxyethylene hydrogenated castor oil 40, 1, 2-propylene glycol and ethyl oleate are adopted to construct a self-emulsifying medicine delivery system to prepare polyphyllin-I nanoparticles, and then the medicines are prepared, so that the bioavailability and targeting property of the medicines are improved. Aiming at the problems of poor curative effect and large side effect when the existing medicine is used for treating ovarian cancer and endometrial carcinoma, the medicine can be prepared by combining polyphyllin-I nanoparticles and rapamycin.

The application belongs to the technical field of fermentation engineering, and relates to application of ethyl linoleate in improving nystatin yield and a fermentation method for high-yield nystatin. The application provides the application of ethyl linoleate in improving the nystatin yield. By using ethyl linoleate as a feed, the yield of nystatin in the process of fermentative production of nystatin can be improved.

The present disclosure relates to compositions including a UV absorbing system including at least one physical ultraviolet (UV)-attenuating material and at least one oil for inhibiting physical ultraviolet (UV)-attenuating material aggregation, as well as to methods of making and using such compositions.

The application belongs to the field of biology and particularly relates to a propandiol-feeding Lactobacillus lentus capable of simultaneously producing 2-nonanol and ethyl oleate and application thereof. The preservation number of the propandiol-feeding Lactobacillus lentus is CGMCC No.25141. The strain can produce 2-nonanol and ethyl oleate with contents of 0.330 mg / L and 0.213 mg / L respectively, and thus can be applied to liquor brewing as a strengthening agent.

The invention discloses a digestion-aiding lactein tablet and a preparation method thereof, and belongs to the technical field of pharmaceutical preparations. The method comprises the following steps: firstly, mixing lactein, cane sugar, aspartame, milk-flavored essence and talcum powder, granulating, adding magnesium stearate, uniformly mixing, and pressing into tablet cores; then preparing a coating solution containing hydroxypropyl methylcellulose, Tween 80, amphiphilic nano lamellar magnesium-aluminum layered double hydroxides, amphiphilic mesoporous silica-zinc oxide hybrid particles, ethyl oleate and polyethylene glycol 400, and then preparing the coating solution containing hydroxypropyl methylcellulose, Tween 80, amphiphilic nano lamellar magnesium-aluminum layered double hydroxides, amphiphilic mesoporous silica-zinc oxide hybrid particles, ethyl oleate and polyethylene glycol 400; and finally, spraying the coating liquid on the surface of the tablet core to obtain a finished product. According to the method, two amphiphilic nano materials prepared by adopting a specific process are combined with coating components to form a coating layer with a specific function. The prepared lactein tablet can effectively protect the core component and improve the action effect of the core component in the intestinal tract, so that the better functions of helping digestion and regulating the intestinal flora are synergistically exerted.

The invention relates to a compound emulsion for preventing and controlling bovine viral diarrhea. Every 100 g of the compound emulsion comprises the following components by weight: 0.1 to 6.0 g of bovine viral diarrhea antibody, 2.0 to 4.0 g of solanum nigrum polysaccharide, 0.1 to 1.0 g of donaxine, 0.1 to 5.0 g of taurine, 1.0 to 3.0 g of ephedra oil, 4.0 to 10.0 g of polyoxyethylene (40) castor oil, 10.0 to 18.0 g of linoleic acid, 14.0 to 20.0 g of ethyl oleate, 15.0 to 25.0 g of span-40, and the balance of water for injection. Primary emulsion of the reemulsion is in an oil-in-water (O / W) type, and secondary emulsion of the reemulsion is in an oil-water mutual wrapping type. The invention further discloses a preparation method, the process controllability is high, and low-cost production is facilitated. The reemulsion can play a slow-release and long-acting role after intramuscular injection, the effective concentration of the antibody can be maintained in vivo for a long time, repeated medication is not needed, the stress reaction of animals is reduced, meanwhile, viruses are neutralized more thoroughly, the overall curative effect is remarkably improved, and the treatment cycle is shortened.

The invention discloses a buparvaquone nano preparation and a preparation method thereof, and belongs to the technical field of pharmaceutical preparations, the active ingredient of the buparvaquone nano preparation is buparvaquone, and every 100g of the buparvaquone nano preparation contains 0.1-3.0 g of buparvaquone, 4.0-8.0 g of caraway oil, 1.0-3.0 g of ethyl oleate, 8.0-12.0 g of glyceryl tristearate, 3.0-5.0 g of lecithin, 1.0-6.0 g of oleyl alcohol, 0.1-1.0 g of anhydrous magnesium chloride and the balance of ethyl caprate. The preparation is a non-aqueous preparation and can play a quick-acting and long-acting role after being injected, drug particles exist in the form of nanospheres, the particle size is distributed between 5.0 nm and 100.0 nm, the bioavailability is high, clinical use is safe, drug resistance does not exist, production is easy to convert, the clinical treatment effect on babesiella bovis infection is remarkably superior to that of the prior art, and the market prospect is good.

The invention belongs to the field of pharmaceutical preparations, and particularly relates to a cough-relieving tea formula oral self-microemulsion as well as a preparation method and application thereof. The cough-relieving tea formula oral self-microemulsion is prepared from the following components in percentage by mass: 27.3 to 50 percent of semen armeniacae amarae extract, 16.7 to 36.4 percent of fistular onion stalk extract, 11.4 to 26.7 percent of mixed oil phase, 7.4 to 17.8 percent of emulsifier and 4.0 to 8.9 percent of co-emulsifier, wherein the mixed oil phase is prepared from zanthoxylum oil, lard oil, oleic acid and ethyl oleate. The preparation method comprises the following steps: weighing the mixed oil phase, the emulsifier and the co-emulsifier according to the prescription, stirring for 1-40 minutes by using a vortex mixer with the rotating speed of 100-600r. Min <-1 > at the temperature of 15-60 DEG C, adding the mixture into pure water, adding the bitter apricot kernel extract and the fistular onion stalk extract, uniformly stirring, and filtering to obtain the product. The oral self-microemulsion is guided by the traditional Chinese medicine theory, a folk dietary therapy cough relieving prescription is explored, the oral self-microemulsion is prepared from the active ingredients of the pepper, the fistular onion stalk and the bitter apricot kernel in the prescription and the lard oil by using the modern preparation technology, and the oral self-microemulsion has the advantages of small particle size, small PDI and good stability, and lays a solid foundation for research and development of export products in the market.

The invention discloses a self-curing injectable pectin hydrogel and a preparation method and application thereof.Based on 100 parts by weight of the hydrogel, the hydrogel is prepared from, by weight, 30-80 parts of Pickering emulsion, 0.5-5 parts of pectin and the balance water, based on 100 parts by weight of the Pickering emulsion, 0.5-5 parts of the pectin and the balance water, and based on 100 parts by weight of the Pickering emulsion, 0.5-5 parts of the pectin are added, the Pickering emulsion contains 2 to 20 parts by weight of pluronic F127 and 0.1 to 5 parts by weight of hydroxyapatite, and on the basis of 100 unit volume of the Pickering emulsion, the Pickering emulsion contains 20 to 70 unit volume of ethyl oleate. According to the hydrogel, hydroxyapatite nanoparticles are used as a hydrogel cross-linking agent and also used as a stabilizer for stabilizing a Pickering emulsion, and a biodegradable pectin substrate is combined, so that the effects of promoting bone repair and preventing tumor recurrence are achieved. The system can effectively promote apoptosis of osteosarcoma cells, inhibit migration of the osteosarcoma cells and regulate and control the cycle of the osteosarcoma cells in vitro, and shows a remarkable anti-osteosarcoma effect and an osteogenesis promotion effect in vivo.

The present invention discloses a moisturizing composition, a preparation method and an application thereof. The moisturizing composition comprises ethyl oleate, ascorbyl methylsilanol pectinate and isomerized sugars in a mass ratio of (0.1-8):(0.1-10):(0.1-10). The ethyl oleate, ascorbyl methylsilanol pectinate and isomerized sugars are prepared into a microemulsion and applied in skin care products. Compared with the prior art, the components of the present invention cooperate synergistically, enhance the skin barrier function while moisturizing, and the instant moisturizing effect and long-term moisturizing effect of the microemulsion moisturizing preparation are superior to those of the same dose of ordinary moisturizers combined.

The application belongs to the technical field of microbial fermentation, and particularly relates to an abnormal williamsonia yeast and application of the abnormal williamsonia yeast in preparation of ethyl palmitate, propyl linoleate or ethyl oleate. Wickerhamomyces anomalus The abnormal williamsonia yeast is abnormal williamsonia yeast Lz5, and is classified and named as abnormal williamsonia yeast Wickerhamomyces anomalus , which is preserved in the China General Microbiological Culture Collection Center on June 19, 2025, has a preservation number of CGMCC No.34954, and an address of the preservation unit is No.3, Institute of Microbiology, Chinese Academy of Sciences, 1, Beichen West Road, Chaoyang District, Beijing. Ethyl palmitate, propyl linoleate and ethyl oleate can be prepared by fermenting sugarcane juice with the abnormal williamsonia yeast. The content of ethyl palmitate in the culture medium after fermentation can reach 13.68 mg / L. After subsequent extraction, the abnormal williamsonia yeast can be used for industrial production.

The invention relates to the technical field of high polymer materials, in particular to a high-toughness composite regenerated plastic and a preparation method thereof, and the high-toughness composite regenerated plastic specifically comprises regenerated polypropylene, KH550 modified TiO2 nanoparticles and surface-treated fly ash; the surface treated fly ash is selected from one or more of isopropyl palmitate treated fly ash, furfuryl palmitate treated fly ash, ethyl myristate treated fly ash and ethyl oleate treated fly ash. On the basis of the prior art, the isopropyl palmitate, the furfuryl palmitate, the ethyl myristate and the ethyl oleate treated fly ash are compounded with the KH550-TiO2 nanoparticles for use, so that the mechanical property of the regenerated polypropylene is further improved. Meanwhile, the number of hydroxyl groups on the surface of the fly ash is further increased through acid treatment, the interface adhesion of the fly ash and the regenerated polypropylene is improved, and the mechanical performance is further improved.

The present application relates to the technical field of high polymer materials, and more particularly to a high-toughness composite recycled plastic and a preparation method thereof, which specifically comprises recycled polypropylene, KH550 modified TiO2 nanoparticles and surface-treated fly ash; the surface-treated fly ash is selected from one or more of isopropyl palmitate treated fly ash, furfuryl palmitate treated fly ash, ethyl myristate treated fly ash and ethyl oleate treated fly ash. On the basis of the prior art, the isopropyl palmitate, furfuryl palmitate, ethyl myristate and ethyl oleate are used to treat the fly ash and are compounded with the KH550-TiO2 nanoparticles, so as to further improve the mechanical properties of the recycled polypropylene. Meanwhile, the number of hydroxyl groups on the surface of the fly ash is further increased through acid treatment, the interfacial adhesion between the fly ash and the recycled polypropylene is improved, and the mechanical properties are further improved.

The present application relates to the technical field of pharmaceutical preparation, and discloses a tulobuterol transdermal patch and a preparation method thereof.The tulobuterol transdermal patch comprises a backing layer, a paste layer and an anti-sticking layer, the paste layer comprises tulobuterol, pressure-sensitive adhesive and a penetration enhancer, the pressure-sensitive adhesive is a copolymer of 2-ethylhexyl acrylate, butyl acrylate, tertiary octyl acrylamide and methyl methacrylate, and the penetration enhancer contains propylene glycol and ethyl oleate.The present application adopts a new pressure-sensitive adhesive matrix, solves the problem that tulobuterol is easy to crystallize out in the patch, and enhances the transdermal effect of tulobuterol by using a penetration enhancer.The present application also discloses a preparation method of the tulobuterol transdermal patch, and the preparation process is improved, so that the loss of tulobuterol in the preparation process is reduced, the quality of the medicine is improved, and the cost is reduced.

The invention relates to the technical field of pesticides, and particularly discloses an epoxiconazole-containing nanoscale bactericide and a preparation method thereof. The epoxiconazole-containing nanoscale bactericide is mainly prepared from the following raw materials in percentage by weight: 10 to 15 percent of epoxiconazole active compound, 1 to 3 percent of tripeptide-1 derivative, 0.3 to 0.7 percent of 1, 3-dimethyl-2-imidazolinone, 1 to 3 percent of sodium lauryl polyoxyethylene ether sulfate, 2 to 4 percent of sodium polyphosphate, 0.5 to 0.9 percent of thickening agent, 0.001 to 0.003 percent of preservative, 3 to 5 percent of antifreezing agent, 0.1 to 0.5 percent of organic silicon defoaming agent and the balance of water. The tripeptide-1 derivative is obtained by treating tripeptide-1 with ethyl oleate. The nanoscale bactericide has the characteristics of being high in epoxiconazole suspension rate, easy to pour and clean, good in storage stability, good in prevention and treatment effect and high in pesticide effect, and meets market requirements.

The invention discloses an absorption-promoting multi-element composite collagen composition and a preparation method thereof, and belongs to the field of cosmetic raw materials, the absorption-promoting multi-element composite collagen composition comprises the following components by mass: 5%-15% of multi-element composite collagen, 0.1%-0.5% of sodium hyaluronate, 3%-7% of ethyl oleate, 2%-5% of azone, citric acid for maintaining pH at 5.5-6.5, and the balance of water, the multi-element composite collagen comprises I type collagen, III type collagen and XVII type collagen. The azone mainly destroys ordered arrangement of cuticle lipid, the ethyl oleate can further dissolve lipid, the combination of the azone and the ethyl oleate can more effectively weaken the barrier effect of skin barrier and promote collagen penetration, and the sodium hyaluronate increases the hydration degree of the cuticle and makes the cuticle swell, so that the compactness of the skin is reduced, and the skin care effect is improved. And a more favorable condition is provided for penetration of the collagen. The formula has good safety and stability, and is suitable for various skin types.

The development of ethyl isooleate obtained from the isomerization of fatty acids from soy, palm, sunflower, rapeseed, peanut and its applications in the cosmetic field, more specifically, in formulations of face creams, body creams and hair conditioners is described. Isomerization creates non-linear branched chains that generate unique properties such as greater emollience, lubricity, solvency, spreadability, thermal and chemical stability, as well as greater fluidity in viscous systems. Ethyl isooleate is free from ocular and skin irritation, being completely non-allergenic. Ethyl oleate is an excellent solvent for active ingredients in ointments, creams, lotions. It works as an excellent excipient in delivery system formulations, helping the penetration of active ingredients into the skin. All of these characteristics above belong to ethyl oleate, however, from a physicochemical point of view, ethyl isooleate has superior properties to its isomer ethyl oleate.

The invention discloses dicyclanil double-layer coated microcapsule suspension. Every 100 g of the dicyclanil double-layer coated microcapsule suspension is prepared from the following components by weight: 0.01 to 2.0 g of dicyclanil, 1.0 to 4.0 g of guinea butter, 0.1 to 1.0 g of ethyl oleate, 5.0 to 10.0 g of polyoxyethylene (8) stearate, 15.0 to 35.0 g of an emulsifier OP-10, 0.5 to 1.5 g of karaya gum, 0.01 to 0.6 g of sclerotium glucan, 4.0 to 10.0 g of glycerol formal and the balance of deionized water. Meanwhile, the invention further discloses a preparation method of the microcapsule suspension, the process operability is high, after the medicine is subjected to double-layer coating treatment, the validity period is remarkably prolonged, the medicine effect is improved, the safety is better, and the market application prospect is wide.

The invention provides a method for preparing human milk substitute fat through multi-step enzyme catalysis transesterification reaction. The method comprises the following steps: catalyzing grease rich in palmitic acid with ethyl oleate and ethyl linoleate by adopting an enzyme to carry out transesterification reaction, after the reaction is finished, crystallizing and separating materials under different low-temperature conditions, and separating out a liquid phase rich in OPO / OPL; the separated solid phase is continuously subjected to an enzyme catalysis reaction until the yield of the product OPO / OPL reaches 90% or above. Compared with a one-step method, the method for preparing human milk substitute fat OPO / OPL based on molecular distillation or acid-base neutralization or adopting a surfactant and solvent fractionation and other traditional two-step or multi-step enzyme method technologies, the method for preparing human milk substitute fat OPO / OPL through multi-step enzyme catalysis transesterification reaction has the advantages of being low in raw material price, mild in reaction condition, free of acid-base use, free of organic solvent introduction, low in carbon and environment-friendly in the whole process, low in cost, easy to operate and the like. And the method has the advantages of simple process operation, easy industrial amplification and the like, and has good industrial application prospects.