64 results about "Retinol" patented technology

The invention discloses a method for extracting retinol from yeast fermentation liquor. The method comprises the following steps: A, extracting the fermentation liquor to obtain an extraction phase; step B, concentrating the extract phase to obtain concentrated oil; step C, purifying concentrated oil; and optionally step D, concentrating the purified eluent.

An oral care composition with retinoid compound, amino acid, and / or olive oil. An oral care composition with retinoid compound, a pentapeptide, such as palmitoyl KTTKS [SEQ ID NO. 2], and / or an olive oil. Methods of preventing gingival recession, stopping gingival recession, reversing gingival recession, decrease gum recession, increase gingival barrier protection, promoting collagen synthesis, promoting extracellular matrix synthesis, increasing gum resilience, increasing epidermal thickness and / or promoting fibrillin synthesis, in an oral cavity of an animal by contacting the oral care compositions with at least one surface of the oral cavity.

The invention provides a whitening and anti-aging extracellular vesicle compound as well as a preparation method and application thereof. The extracellular vesicle compound comprises extracellular vesicles derived from mesenchymal stem cells and active ingredients loaded in the extracellular vesicles, the active component comprises any one or a combination of at least two of retinoic acid, arbutin, panthenol, nicotinamide, ectoine, vitamine, hyaluronic acid, vitamin C, resveratrol or retinol; the ratio of the extracellular vesicles to the active ingredients is (1-10) * 10 < 8 >: (0.01-1) mg. The skin-care active ingredients are entrapped in the extracellular vesicles derived from the mesenchymal stem cells, so that the delivery efficiency of the skin-care active ingredients can be remarkably improved, the direct irritation of free components to the skin can be reduced, the generation of matrix metalloproteinase-1 (MMP-1) and melanin can be effectively inhibited, the light aging process of the skin can be delayed, and the skin-care composition has excellent whitening and anti-aging effects.

Suggested is an active mixture, comprising or consisting of (a) retinol and / or at least one retinol compound (b) at least one physiological cooling agent, wherein component (a) is present in an amount from 35 to 200 wt.-percent calculated on the amount of component (b).

The invention discloses a retinol / saccharomycetes protein polypeptide copolymer as well as a preparation method and application thereof, and relates to the field of biology. The preparation adopting the yeast polypeptide to entrap the retinol is created, the yeast polypeptide is extracted from yeast autolysis supernatant, the yeast autolysis supernatant adopts animal-derived protein as a nitrogen source for fermentation, the content of the retinol entrapped by the yeast polypeptide is remarkably increased, and the preparation is remarkably superior to the retinol in the aspects of stability, mildness, efficacy and the like.

The invention discloses liquid medicine for treating scalds. The liquid medicine is prepared by adding 0.1 to 0.17 g of calcium hydroxide, 0.05 to 0.5 g of carbohydrate, 95 to 100g of fatty acid, 0.05 to 0.2 mg of retinol, 60 to 70mg of vitamin E, 5 to 12mg of calcium, 2 to 6mg of phosphorus, 1 to 1.5 mg of sodium, 1 to 5mg of magnesium, 2 to 3mg of iron, 0.1 to 0.2 mg of zinc, 0.01 to 0.1 mg of copper, 0.5 to 1mg of manganese, 2 to 5mg of sesamol and 1 to 6mg of sesamin into every 100g of water. According to the invention, calcium soap generated by reaction of fatty acid and calcium hydroxide is utilized to quickly form a layer of physical protection barrier on a scald wound surface, so that the purposes of isolating air, reducing pollution, relieving pain and limiting exudation can be achieved; through cooperation of vitamin E, sesamol and sesamin, oxidative stress and inflammatory response generated after burn can be resisted, tissues are protected, symptoms are relieved, and repair is promoted. The components of the traditional Chinese medicine have a synergistic effect, so that the traditional Chinese medicine can be used for effectively treating scalds and is short in treatment period; and after the ointment is used for treating the scald wound, no scar is left.

Pharmaceutical or cosmetic composition comprising the following components: a) a dermatologically suitable carrier material, b) a first active substance, and c) a second active substance; wherein d) the first active substance comprises royal jelly; and e) the second active substance comprises retinol, a retinol analogue or a mixture thereof.

Provided are a method of producing retinol, the method comprising the step of culturing a microorganism of the genus Yarrowia in a medium comprising a non-ionic surfactant; a method of increasing retinol production; a method of producing retinoids; a medium composition for a microorganism of the genus Yarrowia for producing retinol, the composition comprising a non-ionic surfactant; a composition for producing retinol, the composition comprising the microorganism or a culture thereof and a non-ionic surfactant.

An oil-in-water emulsion having an SPF of at least 25, comprising: (a) at least 0.01 wt.% of one or more types of retinol selected from the group consisting of retinol, retinaldehyde, retinoic acid, or a combination thereof; (b) one or more water soluble antioxidants; (c) one or more oil soluble antioxidants; (d) at least 10 wt.% of one or more oil soluble or oil dispersible sunscreen components. Methods of making the oil-in-water emulsions as well as uses and methods of use of the oil-in-water emulsions.

The invention discloses a water-light makeup pre-emulsion and a preparation method thereof. The water-light makeup pre-emulsion comprises nicotinamide, retinol, 3-o-ethyl ascorbic acid, moringa seed oil, hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer, a humectant, an emulsifier, a thickener, a preservative, a pH regulator and deionized water. Nicotinamide, retinol, 3-o-ethyl ascorbic acid and moringa seed oil are compounded, so that the nicotinamide is used for remarkably buffering the potential irritation of the retinol; 2, 3-o-ethyl ascorbic acid and retinol form day and night synergy for resisting oxidation and promoting collagen synthesis, moringa seed oil serves as a lipid carrier to pre-disperse and wrap retinol, a water sample is physically isolated, and the problem that retinol and vitamin C derivatives are difficult to coexist is solved; the final product is moist and light in texture, presents natural water and light sensation after being smeared, can effectively smooth the skin and enhance the fitting degree of subsequent base makeup, and is free of mud rubbing burden.

The invention discloses a cosmetic formula, and aims to provide an anti-wrinkle skin care composition which can improve the synergistic effect of the formula, can contain water-soluble GHK tripeptide and fat-soluble palmitoyl GHK tripeptide at the same time, and is compounded with retinol, and a preparation method of the anti-wrinkle skin care composition. According to the key points of the technical scheme, an oil phase, a water phase, an antioxidant and active substance phase and a final phase are combined, and a special preparation process is adopted, so that the problems that water-soluble GHK tripeptide, fat-soluble palmitoyl GHK tripeptide and unstable retinol coexist in the same formula and stably and efficiently play roles are effectively solved; the overall anti-wrinkle, firming and repairing synergistic effect of the formula is remarkably improved, the comprehensive anti-aging effect which is difficult to achieve through a single component or simple compounding is achieved, and the composition is suitable for the technical field of cosmetic formulas.

The invention provides an anti-aging fusion vesicle as well as a preparation method and application thereof. The fusion vesicle comprises a fusion product of extracellular vesicles derived from mesenchymal stem cells and lipidosome, the liposome comprises a carrier formed by assembling phospholipid, cholesterol and an amphiphilic polymer, a fat-soluble active matter loaded on a hydrophobic layer of the carrier and a water-soluble active matter loaded on a hydrophilic inner cavity of the carrier, the fat-soluble active matter comprises any one or a combination of at least two of retinoic acid, resveratrol or retinol; the water-soluble active matter comprises any one or a combination of at least two of arbutin, panthenol, nicotinamide, ectoine, glassine, hyaluronic acid or vitamin C. The fusion vesicle provided by the invention can significantly improve the delivery efficiency of active skin care components, reduce the direct irritation of free components to skin, effectively inhibit the expression quantity of matrix metalloproteinase-1 and delay the photoaging process of skin, and has an excellent anti-aging effect.

Skin care compositions and, e.g., skin care compositions containing retinol and salicylic acid are disclosed herein. In accordance with one aspect, provided is a skin care composition comprising: a retinoid; salicylic acid, and / or a salt thereof; from about 1.5 to about 17 wt.% of a silicone; from about 1 to about 8 wt.% of a vitamin B; from about 5 to about 40 wt.% of a fatty component; and water, wherein the skin care composition has a pH of about 4.75 to about 6.7 and all weight percentages are based on the total weight of the skin care composition.

This application relates to a Yarowia liporitica microorganism with enhanced SNQ2 protein activity and retinoid-producing ability, a method for producing retinoids using the same, a composition for retinoid production, its use in retinoid production, and a method for producing the said microorganism.

The application discloses a method for simultaneously detecting retinoids and lipid-soluble vitamin metabolic marker groups in biological samples and matching reagents. The application is based on magnetic bead solid-phase extraction technology, significantly improves sample purification effect, and reduces matrix interference; in combination with a high-aqueous-phase reversed-phase chromatography system and a positive-negative ion switching multi-reaction monitoring mode, simultaneous separation and detection of seven retinoid molecules and a full spectrum of lipid-soluble vitamins are realized. The method has high sensitivity, strong specificity and wide detection range, and for the first time realizes one-stop analysis across species and sample types, thereby providing reliable platform support for clinical and scientific research applications.

The present application relates to a method for producing retinol comprising a step of culturing a Yarrowia microorganism in a medium containing an antioxidant, a method for increasing retinol production, a method for producing a retinoid, a medium composition for a Yarrowia microorganism for producing retinol containing an antioxidant, and a composition for producing retinol comprising the microorganism or a culture thereof and an antioxidant.

Disclosed herein are compositions suitable for use in food, feed, pharmaceutical, and cosmetic products, comprising a retinoid component and its fermentation residue. In one embodiment, the retinoid component is present in a weight ratio to the fermentation residue of 4:1 or greater, the retinoid contains cis- and trans-isomers, and the cis-isomer is present in an amount of less than 3% by weight of the total isomer mixture. Preferably, the composition is biobased. Biotechnology methods for producing the compositions described elsewhere are also described, as well as additional methods for processing such compositions into more stabilized, more commercially acceptable forms. Finally, food, feed, pharmaceutical, and cosmetic products incorporating the compositions described herein are also disclosed.

The present invention addresses the problem of providing a novel topical skin preparation. The present invention provides a topical skin preparation or the like containing glycylglycine and retinol acetate.

The present application relates to: a Yarrowia genus microorganism having a retinol-producing ability, in which the activity of an ABC3 protein is reduced as compared to the endogenous activity thereof; a retinol production method using the same; a method for producing a microorganism of the genus Yarrowia having a retinol-producing ability; the invention discloses a method for enhancing retinol release of microorganisms. And a composition for producing retinol.

This application relates to a microbial oil composition containing retinoids and fatty acids, a cosmetic composition, a food composition, a feed composition containing the same, and a method for producing the same.

A composition including a retinol-like agent to be used for scalp and hair health and hair growth. In one exemplary embodiment, the composition includes a carrier, a retinol-like agent, and a hydrating agent. Additional ingredients include a solubilizer, a thickener, and a preservation agent to form a scalp serum. In a hair and scalp mask, the composition includes a carrier, one or more conditioning agents, a preservation agent, a moisturizing agent, a retinol-like agent, and at least one pH adjuster. Either the scalp serum or the scalp and hair mask can further include vitamins, proteins, chelating agents, antioxidants, oils, acids, and other actives that promote hair growth.

Rechargeable and non-rechargeable collared containers for airtight packaging of oxygen and / or moisture sensitive liquid formulas, such as retinol and retinol-containing compositions, for preservation of these substances. Collared containers include inner container collars that are able to be coupled with inner containers that store cosmetic substances therein. The inner container collars are securable to outer containers, and dispenser collars are securable to the outer containers for airtight storage and delivery of cosmetic substances within and from the inner containers and prevention of exposure of the cosmetic substances to air outside the outer containers. Airless pump dispensers can be used for creation of vacuums and maintenance of air-tight seals, and inner containers can be flexible pouches, flexible blow mold bottles, or rigid containers containing pistons.

The invention relates to the field of cosmetics, in particular to a functional anti-aging microcapsule composition for cosmetics and a preparation method of the functional anti-aging microcapsule composition. The composition is prepared from the water, the sodium alginate, the retinol, the composite plant extract, the triglyceride (ethylhexanoate) and the stabilizer, and the composition has excellent anti-aging and anti-inflammatory functions and the like, can effectively moisten skin, is high in stability and can effectively resist adverse effects caused by a temperature environment.

We demonstrate that supplementation with resistant potato starch (RPS) influences the circulating levels of retinol, alpha-tocopherol, choline, and the choline-derived phospholipid sphingomyelin in serum. Levels of the toxic microbially transformed choline metabolites trimethylamine and trimethylamine oxide did not increase, suggesting that RPS may be an e ective way to enhance choline uptake without promoting increased toxic metabolite production. Increased hydroxysphingomyelin levels in RPS consuming individuals are particularly intriguing given the role these metabolites play in myelin.

The application relates to the cosmetic technical field, in particular to a retinol microcapsule condensation pearl anti-wrinkle firming triple collagen essence cream and a preparation method thereof. The essence cream provided in the application realizes the balance of retinol slow release stability, mild low stimulation, whole-layer collagen activation and barrier repair performance, and avoids the problems of easy oxidation failure of existing retinol skin care products, relatively high irritability of raw materials, weak transdermal absorption of ordinary collagen products, single anti-aging dimension of single active ingredient, low purification efficiency and insufficient activity of conventional plant extracts. The essence cream provided in the application can be used for facial skin anti-wrinkle firming and daily barrier repair and maintenance, and is suitable for the use requirements of long-acting anti-aging, mild stability maintenance and multi-dimensional skin repair of mature skin and sensitive skin.

Anti-aging care kit for keratin materials The present invention relates to a kit, preferably for the care of keratin materials, comprising: - a first composition comprising between 1% and 8% by weight, relative to the total weight of the first composition, of an alpha-hydroxy acid, and optionally a beta-hydroxy acid, - a second composition comprising between 2% and 15% by weight, relative to the total weight of the second composition, of ascorbic acid and / or one of its derivatives, - a third composition comprising at least one UV filter, and - a fourth composition comprising between 0.05% and 1% by weight, relative to the total weight of the fourth composition, of retinol and / or one of its derivatives, in which the first composition, the second composition, the third composition and the fourth composition are each placed separately from each other.The present invention also relates to a method for caring for keratin materials comprising the application of the compositions of the kit according to the invention according to a specific sequence. Figure for abstract: None.

The invention relates to an active mixture comprising or consisting of (a) retinol and / or at least one retinol compound and (b) at least one physiological freshener, the content of component (a) being 35 to 200% by weight, in the amount of component (b).

A method for improving the effectiveness and reducing the irritation of retinol application by introducing a two-step evening skincare regimen, referred to as “Retinol Staging.” The method includes cleansing the skin and applying a moisturizer in the early evening to enhance hydration and barrier function, followed by a waiting period to allow absorption. Retinol is then applied at bedtime to maximize efficacy and minimize side effects. This approach differs from existing methods like “retinol sandwiching” and “skin cycling,” offering superior hydration and skin barrier protection.

The present invention discloses a skin care composition, comprising a first active component and a second auxiliary component. The first active component is selected from one or more of tetrahydrocurcumin, ergothioneine, phloretin, arbutin, resveratrol, vitamin C, dipotassium glycyrrhizinate, ceramide, Aloe vera polysaccharide, Opuntia dillenii polysaccharide, Astragali radix polysaccharide, Dendrobii caulis polysaccharide, Cucumis metuliferus polysaccharide, fucoidan, small-molecule hyaluronic acid, pearl powder, collagen, tea tree essential oil, thearubigins, salicylic acid, retinol, glycoxyl, carnosine; the second auxiliary component is selected from one or more of tetrahydropiperine, laurocapram, PEG-75 shea butter glycerides, hydrogenated castor oil, glycerol, lauric acid, sucrose laurate, butanediol, polysorbate, hydroxyethyl cellulose, 1,2-pentanediol, ethoxydiglycol. The skin care composition of the present invention can be used for whitening, anti-inflammatory, anti-glycation, moisturizing, skin firming, anti-bacterial and / or anti-aging.

1. Name of the designed product: packing bottle (serum protein retinol essence cream). 2. Use of the designed product: for packing of products. 3. Design points of the designed product: combination of shape and pattern. 4. Picture or photo best indicating the design points: perspective view.