1215 results about "Skin damage" patented technology

A method and apparatus is provided for identifying imperfections in a person's facial, forearm or hand skin and for recommending an appropriate remedial cosmetic. The method includes providing an apparatus having a programmable computer, a camera connected to the computer, at least one visible wavelength light source for separately generating at least two different color images and at least one ultraviolet wavelength light source for an ultraviolet light image. Further, the method includes placing the ultraviolet and color images into a program of the computer and processing the images for pinpointing areas of skin requiring preventative treatment including those with skin damage. A remedial set of cosmetic products can thereby be recommended.

The present invention provides a composition comprising an effective amount of benfotiamine and an effective amount of pyridoxamine in a suitable vehicle for topical application. The present compositions are useful in improving the appearance of aged skin characterized by wrinkles, loss of elasticity, and hyperpigmentation caused by chronoaging and/or photoaging of skin, by inhibiting particularly skin damage resulting from reactive carbonyl species (RCS), glycation of skin proteins, formation of advanced glycation endproducts (AGEs) and formation of advanced lipoxidation endproducts (ALEs).

Methods are provided for enhancing the permeability of skin or mucosal tissue to topical or transdermal application of pharmacologically or cosmeceutically active agents. The methods entail the use of a base in order to increase the flux of the active agent through a body surface while minimizing the likelihood of skin damage, irritation or sensitization. The permeation enhancer can be an inorganic or organic base. Compositions and transdermal systems are also described.

New or significantly changed skin lesions are detected by providing digital baseline image data of an area of a subject's skin by placing a calibration piece on the area and then positioning a digital camera to frame the area within a field of view of the camera and digitally photographing the area to produce a digital baseline image of the area. The digital baseline image is downloaded from the camera to a computer, which digitally filters the baseline image to produce a partially transparent baseline image scaled to fit over a viewfinder display of the camera. The filtered baseline image is printed on a transparent sheet to produce template. Substantially later, a calibration piece is placed on the area, and the template is placed over the viewfinder display of the camera. The camera is positioned to frame that area within the field of view so as to align a live image of the area with the baseline image on the template. The area is photographed to produce a digital current image thereof. The current image is downloaded to the computer, which is operated to alternately display the aligned current image data and the baseline image data to allow visual identification of lesions which changed enough in the “alternating image comparison display” to identify a new or significantly growing lesion.

The present invention provides a delivery system and method to deliver topically homeopathic amounts of at least one Homeopathic Complex. It further provides a Homeopathic Colored Pigment Product containing a coloring agent having a plurality of particles having at least one surface and a homeopathically effective amount of at least one Homeopathic Complex, wherein the at least one surface of particles in the plurality of particles of the coloring agent contains the at least one Homeopathic Complex. It also provides cosmetic formulations containing the Homeopathic Colored Pigment Product for normal skin, problem skin, aged skin, and skin damaged by the harmful rays of the sun.

The present invention relates to findings that reducing the activity of Plasminogen Activator Inhibitor-1 (PAI-1) suppresses an excessive deposition of collagen which is known as a cause for the formation of abnormal scars. These abnormal scars include but are not limited to keloids, adhesions, hypertrophic scars, skin disfiguring conditions, fibrosis, fibrocystic conditions, contractures, and scleroderma, all of which are associated with or caused by an excessive deposit of collagen in a wound healing process. Accordingly, aspects of the present invention are directed to the reduction of PAI-1 activity to decrease an excessive accumulation of collagen, prevent the formation of an abnormal scar, and/or treat abnormal scars that result from an excessive accumulation of collagen. The PAI-1 activity can be reduced by PAI-1 inhibitors which include but are not limited to PAI-1 neutralizing antibodies, diketopiperazine based compounds, tetramic acid based compounds, hydroxyquinolinone based compounds, Enalapril, Eprosartan, Troglitazone, Vitamin C, Vitamin E, Mifepristone (RU486), and Spironolactone to name a few. Another aspect of the present invention is directed to methods of measuring PAI-1 activity in a wound healing process and determining the propensity of the formation of an abnormal scar.

A shaped charge and a method of using such to provide for large and effective perforations in oil bearing sandy formations while causing minimal disturbance to the formation porosity is described. This shaped charge uses a low-density liner having a filler material that is enclosed by outer walls made, preferably, of plastic or polyester. The filler material is preferably a powdered metal or a granulated substance, which is left largely unconsolidated. The preferred filler material is aluminum powder, or aluminum particles, that are coated with an oxidizing substance, such as TEFLON®, permitting a secondary detonation reaction inside the formation following jet penetration. The filled liner is also provided with a metal cap to aid penetration of the gun scallops, the surrounding borehole casing and the cement sheath. The metal cap forms the leading portion of the jet, during detonation. The remaining portion of the jet is formed from the low-density filler material, thereby resulting in a more particulated jet. The jet results in less compression around the perforation tunnel and less skin damage to the proximal end of the perforation tunnel.

Single phase microemulsions improve the removal of filter cakes formed during drilling with oil-based muds (OBMs). The single phase microemulsion removes oil and solids from the deposited filter cake. Optionally, an acid capable of solubilizing the filter cake bridging particles may also be used with the microemulsion. In one non-limiting embodiment the acid may be a polyamino carboxylic acid. Skin damage removal from internal and external filter cake deposition can be reduced. In another optional embodiment, the single phase microemulsion may contain a filtration control additive for delaying the filter cake removal, destruction or conversion.

A skin resurfacing device for peeling the outermost layer of the skin for renewing the skin surface and repairing skin damage including a housing, a skin sensor, and a skin treater. The skin treater consists of an abrasive tip, a first end, a transparent portion, a first filter, and a second end, all of which are detachable and replaceable. The skin treater is connected to a vacuum source by a tubular hose. The vacuum provides both closeness of contact between the abrasive tip and the user's skin and the suctioning of skin debris peeled off. The skin treater, especially the abrasive tip are made with common material and mass production process so that they are disposable and economic.

Methods for diagnosing skin lesions are disclosed. Generally, the method include topically administering an IRM compound to a treatment area for a period of time and in an amount effective to cause a visible change in the appearance of a skin lesion including, in some cases, causing subclinical lesions to become visible. Suitable IRM compounds include agonists of one or more TLRs.

The present invention describes breathable multilayered adhesive structures that can be used as adhesives to mount devices onto the skin. The breathable multilayered adhesive structures can comprise moisture-wicking layers adhered to the skin by a porous adhesion layer. The pores allow moisture released from the skin to be transferred away through the moisture-wicking layer. The adhesive structures permit the devices to be skin-mounted for an extended period of time (e.g., a few hours or days) without causing moisture-associated skin injuries such as erythema, maceration, and irritation or inflammation.

A process and laser system for in vitro and in vivo pain research, pain clinical testing and pain management. In preferred embodiments of the present invention a diode laser operating at a 980 nm wavelength is used to produce warmth, tickling, itching, touch, burning, hot pain or pin-prick pain. The device and methods can be used for stimulation of a single nerve fiber, groups of nerve fibers, nerve fibers of single type only as well as more the one type of nerve fibers simultaneously. The present invention is especially useful for research of human/animal sensitivity, pain management, drug investigation and testing, and psychophysiology/electrophysiology studies. The device and methods permit non-contact, reproducible and controlled tests that avoid risk of skin damage. Applicant an his fellow workers have shown that tests with human subjects with the process and laser of the present invention correlate perfectly with laboratory tests with nerve fibers of rats. The device and the methods can be applied in a wide variety of situations involving the study and treatment of pain. Preferred embodiments of the present invention provide laser systems and techniques that permit mapping and single mode activation of C fibers and A-delta fibers.

A composition is provided to treat and/or prevent for treating skin conditions including fine lines and wrinkles, acne rosacea, surface irregularities of the skin and hyper-pigmentation melasma of the skin, which includes use of a topically applied composition such as an ointment, lotion, cream, serum, gel or pad applied formulation, containing an effective amount of polyphenols, such as green tea based polyphenols, including but not limited to catechins, such as epigallocatechin gallate (EGCG), epigallocatechin (EGC), epicathechin 3-gallate (ECG) and epicatechin (EC). The formulation is preferably composed of 90 percent polyphenol isolates, derived from green tea with potent antioxidant properties, to assist in minimizing free-radical induced skin damage.

The present disclosure is directed to a system and methods for maintaining or improving hand health and hygiene. More particularly, the system and methods prevent or overcome skin damage caused by frequent hand washing and use of hand sanitizers and/or cleansers. The hand care system comprises an article, such as an elastomeric glove, that has a moisturizing liquid liner composition on the skin-contacting surface of the article that delivers a skin health benefit to the skin, a non-irritating hand cleanser capable of moisturizing the skin, and a moisturizing hand sanitizer.

The invention relates to an alginate-based hydrogel dressing and a preparation method thereof, and belongs to the technical field of medical supplies. Raw materials of the invention are a compound of sodium alginate or other alginates and a thickener, a moisturizer and other functional matters, are subjected to swelling dosing, pre-crosslinking, film coating, spray crosslinking, constant-temperature crosslinking plasticizing and film-covering shear forming, and are then prepared into a three-dimensional water-containing grid structure through covalent cross-linking and ion cross-linking. The medical hydrogel dressing is a topical gel dressing, has good moisturizing performance, toughness and adhesion, is mainly suitable for superficial skin damage, such as cut wound, lacerated wound, scratch, burns, suture wounds and the like, protects skin wound healing of a patient, has effects of easing pain, inhibiting bacteria, resisting inflammation, keeping the wound moist, promoting wound healing, and improving the wound repairing quality, is more suitable for treating bedsore wounds, ulcer wounds and other sites hard to be bound after a surgery, can also be used for non-wound sites, and plays a role of moisturizing.

Methods, Devices and systems for hair removal combine the application of RF electromagnetic energy to the skin with application of heat from heating element(s) to hair(s) of the skin. The devices or systems may include RF electrodes and one or more heating elements. RF energy from an RF generating unit is applied to the RF electrodes. Heat is applied to hair shafts by the heating element(s). The devices and systems may be hand held or may include a hand held part connected to a base unit. In operation, the hand held device or part is moved along the treated skin region. The combined effect of RF energy application to the skin and heating of the hair shaft results in improved hair removal and may reduce hair re-growth. The devices and systems may also include safety improving features preventing skin damage by reducing sparking or excessive skin heating by the heating element(s).

A system and method for using near-infrared or short-wave infrared (SWIR) light sources for early detection and monitoring of breast cancer, as well as other kinds of cancers may detect decreases in lipid content and increases in collagen content, possibly with a shift in the collagen peak wavelengths and changes in spectral features associated with hemoglobin and water content as well. Wavelength ranges between 1000-1400 nm and 1600-1800 nm may permit relatively high penetration depths because they fall within local minima of water absorption, scattering loss decreases with increasing wavelength, and they have characteristic signatures corresponding to overtone and combination bands from chemical bonds of interest, such as hydrocarbons. Broadband light sources and detectors permit spectroscopy in transmission, reflection, and/or diffuse optical tomography. High signal-to-noise ratio may be achieved using a fiber-based super-continuum light source. Risk of pain or skin damage may be mitigated using surface cooling and focused infrared light.

The invention discloses a dermatoscope image segmentation method based on a multi-branch convolutional neural network. The method comprises the following steps of 1, collecting training samples; 2, expanding the image; 3, designing a multi-branch convolutional neural network model; 4, training the multi-branch convolutional network; 5, generating a skin damage distribution probability graph; 6, obtaining a segmentation result. The method has the advantages that the training data set is effectively expanded by using the corresponding image transformation according to the data characteristics ofthe dermatoscope image, so that the network training is effective, and the generalization performance is high; the convolutional neural network comprises a plurality of branches, rich semantic information and detail information are fused, compared with a common network, the skin lesion edge can be better recovered, and a more accurate skin lesion segmentation result is obtained; the method is a full-automatic segmentation scheme, only the dermatoscope image to be segmented needs to be input, the segmentation result of the image can be automatically given through the scheme, the additional processing is not needed, and the method is efficient, simple and convenient.

The present invention relates to a topical or cosmetic system that includes a first element capable of acting as an electron donor and a second element capable of acting as an electron acceptor. Such first and second elements are spaced apart by a predetermined distance across a skin surface. The system also includes a third element extending over the predetermined distance across the skin surface, while the third element contains an electrically conductive medium for electrically connecting the first and second elements, thereby generating an electrical current that flows across the skin surface from the first element through the conductive medium to the second element in the absence of any power source. The present invention also relates to methods of using the above-described system for preventing or treating skin damage.