601 results about "Skin damage" patented technology

The invention relates to an aircraft surface damage area segmentation method based on adaptive multi-modal fusion, belongs to the technical field of nondestructive testing, and solves the technical problem of low segmentation precision of an aircraft skin curved surface falling damage area. Obtaining a grey-scale map, a depth map and a point cloud map of the aircraft surface damage skin; synthesizing the grey-scale map, the depth map and the point cloud map, and performing preprocessing, feature extraction, feature conversion, image display and projection and weighted fusion on the synthesized grey-scale map, the synthesized depth map and the synthesized point cloud map to obtain a total edge probability map of skin damage; and performing targeted screening, continuity detection, connectivity detection, convex hull construction, marking and skin falling damage area division on the total edge probability graph. The method is used for aircraft skin health monitoring, maintenance guarantee and operation and maintenance.

The invention provides a radiotherapy patient skin injury real-time detection record management system based on image processing, and belongs to the technical field of radiotherapy patient skin injury real-time detection. Comprising a multispectral image acquisition module for imaging the skin of a patient at the same visual angle by adopting different spectrums to obtain three spectral images including near-infrared imaging, infrared imaging and ultraviolet imaging; a first identification module is used for fusing three spectral images to obtain an image data set, and a second identification module is used for constructing an epidermis injury coefficient # imgabs0 #, a dermis injury coefficient # imgabs1 # and a subcutaneous injury coefficient # imgabs2 # of the ith patient and evaluating the epidermis injury coefficient # imgabs0 #, the dermis injury coefficient # imgabs1 # and the subcutaneous injury coefficient # imgabs2 # respectively. A skin injury evaluation model is constructed, the comprehensive injury area ratio is calculated, the classification of injury levels is realized, data support is provided for a personalized treatment scheme, and a powerful auxiliary diagnosis tool is provided for a medical institution.

The embodiment of the invention provides an aircraft skin damage identification method and device, equipment, a storage medium and a product. The method comprises the following steps: acquiring an initial point cloud of an aircraft skin surface through structured light equipment, and performing data preprocessing on the initial point cloud to obtain a preliminary correction point cloud; calculating reflection intensity distribution of each area on the surface of the aircraft skin based on the preliminary correction point cloud, and determining a compensated point cloud; extracting geometric features from the compensated point cloud, and performing denoising processing on the compensated point cloud to obtain a denoised point cloud; constructing a three-dimensional grid model representing a three-dimensional structure of the aircraft skin surface based on the de-noised point cloud, and determining a damage candidate area of the aircraft skin surface; obtaining a point cloud subset associated with the damage candidate area and carrying out damage type classification on the point cloud subset to obtain a classification result of damage types; according to a classification result, generating a damage labeling graph; and based on the damage marking graph, calibrating the damage size parameter to generate a final damage report.

The invention relates to the technical field of material nondestructive testing, in particular to a CFRP wing skin damage positioning system and method based on multi-modal signal processing and Bayesian optimization DSCN, and the method comprises the steps: carrying out permutation entropy analysis and Higuchi fractal dimension analysis on a signal data set received by a sensor; performing time-frequency feature extraction on the sensor receiving signal data set deviating from the reference; performing damage feature screening on the signal data in the effective time period; training the DSCN structure to obtain an initial CFRP wing skin damage positioning prediction model; performing hyper-parameter optimization on the initial CFRP wing skin damage positioning prediction model according to a Bayesian algorithm; and performing damage positioning prediction on a to-be-detected sample according to the final CFRP wing skin damage positioning prediction model to obtain a corresponding CFRP wing skin damage positioning result. According to the method, effective damage features can be accurately and efficiently extracted from complex signals, and the accuracy and efficiency of CFRP wing skin damage positioning are remarkably improved.

The present invention provides a phycocyanin-collagen composite hydrogel and its preparation method and application. The present invention utilizes transglutaminase to catalyze the combination of phycocyanin and collagen to form a new, more stable collagen; transglutaminase acts between protein molecules, utilizes lysine and glutamic acid in phycocyanin and collagen to transfer acyl groups, and cross-links to form new chemical bonds, thereby enhancing the binding strength of phycocyanin and collagen; the hydrogel prepared by the present invention can be used to prepare medical materials and combined with skin injury sites to solve the problem that traditional dressings are easy to adhere to wounds and easily penetrated by tissue fluid and become infected. In addition to ensuring basic air permeability, it reduces the adhesion of the dressing, increases moisture retention and antioxidant properties, and avoids secondary damage when replacing a new dressing. The hydrogel prepared by the present invention has a certain antioxidant capacity and can be used to prepare products with antioxidant effects.

The invention discloses a therapeutic nano-vesicle preparation rich in mitochondrial functional protein, a preparation method of the therapeutic nano-vesicle preparation and application of the therapeutic nano-vesicle preparation in treatment of radioactive skin injury. The preparation method comprises the following steps: culturing, amplifying and cleaning umbilical cord mesenchymal stem cells, dispersing the umbilical cord mesenchymal stem cells in a suspension, mechanically extruding the umbilical cord mesenchymal stem cells into a crude solution through a multistage aperture polycarbonate membrane, and centrifuging, concentrating and purifying the crude solution to obtain the preparation. The preparation has the remarkable advantages that local administration can be realized, inflammation can be quickly inhibited, oxidative stress is reduced, and a repair pathway is activated, so that the preparation is suitable for treating acute radioactive skin injury; the preparation method is easy to standardize and scale, high in stability and convenient for emergency storage and delivery, and avoids the defects of cell therapy; a plurality of targets such as immune inflammation, oxidative stress and the like can be synergistically regulated, the biological effect of hUMSCs is simulated and partially replaced, and the limitation caused by the cell survival rate and the microenvironment dependency is avoided; the key function of hUMSCs is covered in function, and the clinical feasibility, safety and emergency suitability of the application level are higher.

An embodiment relates to a light emitting diode (LED) mask for personal combination stimulation, which is to be worn on a face, and more specifically to an LED mask for personal combination stimulation, which can prevent skin damage due to heat generation caused by light emission in an LED, reduce manufacturing and maintenance costs, and effectively make improvement such as whitening facial skin, reducing wrinkles, in particular, wrinkles around eyes. The LED mask for personal combination stimulation includes a mask unit to be put on the face of a user; and a light irradiation unit installed in the mask unit and including a plurality of LEDs arranged on a substrate, wherein the LEDs comprise multiple types of LED chips to emit light of different wavelengths, and the multiple types of LED chips are configured as a combination LED module in a single support structure and arrange on the substrate.

The invention belongs to the technical field of microorganisms, and particularly relates to an extracellular vesicle of phytobacterium plantarum and application of the extracellular vesicle. Specifically, the plant lactobacillus extracellular vesicles can promote HaCaT cells to generate ceramide, up-regulate expression of key genes in a skin ceramide synthesis route and recover a skin barrier; the expression of proinflammatory factors in a cell inflammation model can be reduced, and a relatively good anti-inflammatory effect is achieved. A mouse skin injury model verifies that the EVs has good skin infiltration capacity and can remarkably reduce the skin injury score, relieve skin itch, improve the skin water content and reduce expression of proinflammatory factors in skin tissue and expression of pruritus-related cell factors.

The invention discloses a transcranial electrical stimulation control method and system for regulating mental fatigue, and belongs to the technical field of mental state regulation. The system comprises an EEG collecting and processing module and an electrical stimulation module which are in wireless communication to form a closed loop. The EEG collecting and processing module collects a forehead lobe three-lead EEG signal, after preprocessing (baseline drift and high-frequency interference are removed through FIR filtering, and eye movement artifacts are removed through combination of wavelet transform and Kalman filtering), the mental fatigue state is classified through an onboard lightweight convolutional neural network (CNN) algorithm, and a control command is generated; the electrical stimulation module receives the command, generates bipolar pulse width modulation transcranial direct current stimulation (tPWMDCs) current, and stimulates the prefrontal lobe. Local low-power-consumption reasoning of EEG signals is achieved, tPWMDCs avoid skin injury, a closed-loop system dynamically adapts to individual differences, portability, safety and accuracy are achieved, and the system is suitable for driving, office and other scenes.

The invention discloses a deep learning aircraft skin damage detection method suitable for a dark light condition, and the method comprises the following steps: enabling an unmanned plane to fly around an aircraft to obtain the original image data of the aircraft skin damage, carrying out the preprocessing of the collected image data, completing the screening and label marking, and carrying out the detection of the aircraft skin damage. The invention relates to the technical field of aircraft skin detection, in particular to an aircraft skin damage detection method based on a PENet network, an aircraft skin damage data set needed by a training network is made, image data of the training data set is input into the PENet network, the dark light information capture rate is increased, and the training data set processed by the PENet is input into an improved yolov8 network and a CSPDarknet backbone network for feature extraction. The SCConv module is used for carrying out CNN compression by using space and channel redundancy between features, redundancy calculation is reduced, learning of representative features is promoted, the training calculation amount is reduced, the model is lightened, the model training time is shortened, an algorithm is deployed on the unmanned aerial vehicle, consumption of manpower and material resources can be greatly reduced, and the detection cost is reduced.

The invention provides cytokine hydrogel as well as a preparation method and application thereof in skin injury repair, and belongs to the technical field of biological medicines. Comprising the following steps: (1) adding beta-GP into a chitosan solution to obtain a CS-beta-GP pregel solution; (2) dissolving Pluronic F127 and hyaluronic acid in a PBS (Phosphate Buffer Solution) until the Pluronic F127 and the hyaluronic acid are completely transparent to obtain an F127-HA solution; and (3) sequentially dissolving trehalose, cordycepin, a cell factor composition and collagen peptide in a PBS solution, incubating to obtain a cell factor mixed solution, and mixing the cell factor mixed solution with the CS-beta-GP pregel solution and the F127-HA solution. According to the invention, a dual temperature-sensitive system is established, the gel can be quickly formed under the conditions of injection at low temperature and body temperature, the effective period of active ingredients is prolonged by utilizing a trehalose stabilization technology, and meanwhile, the anti-inflammatory effect of cordycepin and the cell repair effect of collagen peptide are combined, so that the efficient repair of skin injury can be realized.

The invention relates to the technical field of automobile electrical detection, provides an automobile wire harness wire insulation skin damage detection method and system, and aims to solve the technical problem that a certain loop insulation skin damage position point is difficult to find in the prior art. Comprising a plane capacitance sensor used for measuring capacitance change between the plane capacitance sensor and a to-be-measured wire harness to obtain a charge signal used for representing the damage state of an insulating material of the to-be-measured wire harness; the charge amplifier is used for performing voltage conversion and amplification processing on the charge signal to obtain a voltage signal; the impedance analyzer is used for calculating impedance through the voltage signal and the current signal, drawing a Bode diagram based on the obtained impedance, and performing index parameter extraction on the Bode diagram to obtain various index parameters; and the upper computer is used for carrying out feature extraction on the multiple index parameters to obtain feature data, and analyzing the damage state of the insulating material of the wire harness to be detected according to the feature data to obtain a detection result.

The invention relates to the field of medical instruments, and discloses a low-temperature scald early warning system for preventing percutaneous acupoint electrical stimulation assisted anesthesia. Comprises: a data acquisition module configured to acquire baseline information of a patient, electric energy output cumulant data of an electrical stimulation device and real-time temperature data of an electrode slice application area; the control module is configured to determine a skin injury risk coefficient based on the patient baseline information, calculate an energy accumulation value of a current application area in combination with the electric energy output accumulation amount data, and calculate an energy accumulation value of the current application area according to a preset low-temperature scald risk model; inputting the skin injury risk coefficient, the energy accumulation value and the real-time temperature data into the low-temperature scald risk model, and calculating to obtain a dynamically adjusted low-temperature scald early-warning threshold value; and when the real-time temperature data reaches the low-temperature scald early-warning threshold value, early-warning information is pushed to a medical care terminal according to a preset time period, and the early-warning information at least comprises an application area position, a current temperature value and suggested examination time.

The invention discloses a saccharomycetes lysate, a preparation method and application, and the main components of the saccharomycetes lysate comprise the following components accounting for the relative content of the saccharomycetes lysate: 93-98% of nucleoside, nucleotide and derivatives thereof; and 0.2 to 6% of amino acid; wherein the nucleoside, the nucleotide and the derivatives of the nucleoside and the nucleotide comprise one or more of adenosine, succinyladenosine, adenosine-3 '-phosphoric acid, inosine and S-adenosine homocysteine. Effect evaluation is carried out on the saccharomycetes lysate, and verification shows that the saccharomycetes lysate has the effects of whitening, repairing skin injury, preventing light and aging, resisting pollution and oxidation, resisting inflammation and relieving, protecting hair and preventing hair loss, replenishing water and preserving moisture, and enhancing skin vitality or removing dark circles.

The invention, which belongs to the technical field of medical image processing and computer vision, discloses a multispectral imaging-assisted post-radiotherapy skin injury early detection system comprising a multispectral data acquisition module, a deep tissue feature extraction module, a three-dimensional lesion segmentation module and a space-time tracking evaluation module. The subcutaneous 2.5 cm depth tissue information is obtained through multispectral imaging at the wave band of 400-1350nm, blood perfusion, melanin concentration, collagen structure and other physiological parameters are inversed based on the radiation transfer theory, a three-dimensional medical image segmentation algorithm is adopted to achieve three-dimensional accurate segmentation of an injury area, a spatio-temporal evolution model is established to predict the injury development trend, and the damage development trend is predicted. The radioactive skin injury can be detected in the subclinical period, the detection time window is advanced by 5.2 days on average, the occurrence rate of severe dermatitis is reduced by 65%, and a basis is provided for clinical timely intervention.

The instant invention relates to a semi-solid topical composition containing Pirfenidone and an antimicrobial / antiseptic agent such as Modified Diallyl Disulfide Oxide (M-DDO) and its preparation process, offering advantages compared to other pharmaceutical forms of topical administration known in the state of the art, useful as antifibrotic, anti-inflammatory and antiseptic agent in the prevention, treatment and reversion of acne and post acne lesions. Said compositions is also useful for reducing skin redness, detaining the formation of new acne outbreaks, reversing already existing outbreaks and regenerating skin damage caused by acne.

The invention discloses a deep learning aircraft skin damage detection method suitable for rain and fog conditions. The deep learning aircraft skin damage detection method comprises the following steps that an unmanned aerial vehicle obtains original image data; preprocessing the image data, and making a data set; inputting the image data of the training data set into the AOD-Net integrated defogging network; inputting the training data set into a CSPDarknet backbone network for feature extraction, and introducing an ECA channel attention mechanism; the method relates to the technical field of aircraft skin damage detection, the damage detection effect of the aircraft skin under the foggy condition can be effectively enhanced, meanwhile, local cross-channel interaction is captured in combination with an ECA attention mechanism, and the detection accuracy is improved. According to the method, the feature response of each channel can be adaptively adjusted, the channels related to the rain stripe features are enhanced, accurate damage detection under most rain and fog conditions can be ensured, and resources can be saved to the maximum extent and the detection cost can be reduced by relying on the lightweight features of AOD-Net and ECA.

The present invention belongs to the field of traditional Chinese medicines, and particularly relates to Leixihaokang, a preparation method therefor, and use thereof. The Leixihaokang of the present invention is prepared from the following active pharmaceutical ingredients in parts by weight: 10 parts of Tripterygium glycosides and 0.1-1.3 parts of Artemisia annua extract. According to the present invention, animal experiments prove that the Leixihaokang can ameliorate renal damage in nephrotic syndrome caused by adriamycin, reduce the occurrence of proteinuria, and reduce the apoptosis of renal tissue cells. Meanwhile, the Leixihaokang of the present invention has a good inhibitory effect on renal, hepatic, splenic, and cardiac toxicity in the treatment process of nephrotic syndrome. According to the present invention, animal experiments also prove that the Leixihaokang can ameliorate skin injury in imiquimod-induced psoriasis, reduce inflammatory infiltration and alleviate skin damage. Meanwhile, the Leixihaokang has a certain degree of inhibitory effect on the hepatic and reproductive system toxicity in the treatment process of psoriasis.

The invention provides a composition and cream with anti-inflammatory and skin barrier injury repairing effects as well as a preparation method and application of the composition and cream, and belongs to the technical field of skin injury repairing. The invention provides a composition with anti-inflammatory and skin barrier injury repairing effects. The composition is prepared from matrine, dipotassium glycyrrhizinate, bisabolol and asiaticoside according to the weight ratio of 1: 1: 1: 1. The composition provided by the invention can play a role through a multi-target mechanism, such as up-regulation of Invoucrin, and provides a more effective prevention and treatment scheme for skin barrier dysfunction related diseases and sensitive skin.

The invention relates to the technical field of biological active peptides, in particular to a method for rapidly and effectively screening light protection active peptides from collagen hydrolysate. The invention relates to an application of a photoprotective polypeptide in preparation of a product. The product has at least one of the following purposes: (1) maintaining or increasing the water content of skin; (2) preventing and / or slowing down skin aging; (3) prevention and / or alleviation of skin UVB injury; and (4) promoting healing of skin wounds or wound surfaces. Two key signal factors (NF-kB, AP-1) and a key matrix metalloproteinase (MMP-9) are screened from a mitogen-activated protein kinase (MAPK) and nuclear factor-kB (NF-kB) pathway to be used as docking targets, and a mimic peptide and the three targets act synergistically to make up for the defect that a single target screening peptide is difficult to comprehensively cope with a light damage multivariate pathway, so that the application of the mimic peptide to the light damage multivariate pathway is realized, and the application of the mimic peptide to the light damage multivariate pathway is realized. And the collagen peptide with excellent light protection activity is obtained through screening.

The invention discloses a phlebitis treatment gel containing a coptis chinensis-wine-treated rhubarb compound component and a preparation method of the phlebitis treatment gel. The active ingredients of the gel are coptis chinensis, rheum officinale and wine-treated rheum officinale in a mass ratio of (1.5-2.5): (1.5-2.5): 1, preferably 2: 2: 1. Lavender essential oil, tea tree essential oil, folium eucalypti essential oil and vinegar frankincense, radix trichosanthis and other traditional Chinese medicine auxiliary materials are used as auxiliary materials. The preparation method comprises the following steps: extracting twice with ethanol, mixing extracting solutions, adding borneol, menthol and essential oil, and finally gelling with carbomer. The phlebitis gel can be independently used or combined with indometacin to form dual-channel anti-inflammation, and the defects of skin atrophy, toxicity accumulation and the like of traditional phlebitis gel are overcome. The traditional Chinese medicine composition is clinically expanded and applied to first-stage pressure sores (without skin damage), acnes and mosquito bites, red and swollen of the first-stage pressure sores fade away within 3-5 days, red and swollen of the acnes are relieved by more than or equal to 60% when the traditional Chinese medicine composition is combined with oral medicine for 48 hours, the itching relieving effect on the mosquito bites is less than or equal to 30 minutes, and the curative effect on phlebitis is remarkably superior to that of 50% magnesium sulfate (Plt;

The invention discloses a colorectal cancer stoma nursing data processing method and device, and relates to the technical field of nursing data processing, and the method comprises the steps: carrying out the time alignment and abnormality elimination of a stoma part sensor signal, image data and subjective feedback of a patient, and forming initial data; the reading is corrected by using the environmental parameters, cross-source verification is carried out, and calibration verification data is output; then, individual baseline features are constructed, the comprehensive risk amount is calculated, and a self-adaptive threshold evaluation record is generated in combination with a first-order iteration dynamic threshold strategy; and when the risk quantity exceeds a threshold value, an alarm is triggered, and the nurse locally verifies and returns a correction factor, so that the model is gradually adaptive. The method can improve the recognition and response efficiency of acute problems such as skin injury, is more accurate in use in various clinical scenes and patient cases, and remarkably improves the stoma nursing quality.

The invention provides a retinyl oligopeptide derivative with anti-aging and wrinkle fading functions and application thereof, and belongs to the technical field of polypeptide derivative application, the retinyl oligopeptide derivative is obtained by connecting a carboxyl terminal of retinoic acid and an amino terminal of oligopeptide, and has a structure as shown in a formula I. In the formula I, n is 1 or 2; l is oligopeptide. The retinoic acid modified oligopeptide derivative provided by the invention has good solubility in both a water phase and an oil phase, is beneficial to product formula design in an application process, has good antioxidant activity and skin cell injury protection activity, can reduce MMP2 and TNF alpha expression increased by ROS in skin fibroblasts, and has a good application prospect. The composition has excellent activity of promoting collagen expression, and has good effects of resisting oxidation, repairing skin injury and smoothing wrinkles when being used for cosmetics or skin care products.

The invention discloses a radioactive skin injury monitoring and early warning analysis method and device based on multi-dimensional data. The method comprises the steps that radioactive skin injury target block image data and corresponding natural data of a patient are collected in real time; a patient skin evaluation function is constructed according to the collected data, and the comprehensive unhealthy degree of the patient skin state is calculated; constructing a patient radioactive skin injury target block early warning function, and calculating a patient skin risk coefficient; on the basis of the radioactive skin injury stability performance description, according to patient target block data and comprehensive unhealth degree which are collected in real time, acquiring patient historical storage data, calculating a patient skin early warning factor of the comprehensive patient historical storage data, and generating a current state description of an injury target block; feedback description of the patient is obtained, and current state description of the damaged target block is updated. According to the method, positive feedback information beneficial to current judgment and nursing is obtained through recorded state recovery or deterioration conditions of similar conditions of the patient, and accurate intervention on the patient is facilitated.

The invention relates to an icaritin and baicalein compound pharmaceutical composition and an application thereof in preparation of a medicine for treating skin injury caused by ultraviolet ray B. The effective dose of icaritin is 0.1 mg / g-0. 5mg / g, and the effective dose of baicalein is 1mg / g-5mg / g. According to the invention, the application range of icaritin and baicalein is expanded, and a theoretical basis is provided for applying icaritin and baicalein to clinical treatment of skin injury caused by UVB.

The invention relates to a medicine for promoting skin injury repair and healing and a preparation method thereof, and belongs to the technical field of biological medicines.The medicine is prepared from a radix astragali preparata extract, lipidosome encapsulated panax notoginseng total saponin-RGD peptide, a honeysuckle flower-maca extract, an asiaticoside-hydroxypropyl-beta-cyclodextrin inclusion compound and dipotassium glycyrrhizinate; the radix astragali preparata extract is a product obtained by moistening radix astragali with honey, baking, extracting with deionized water, and adsorbing and purifying with a Sephadex G-15 column; the honeysuckle-maca extract is a product obtained by mixing dry honeysuckle powder and dry maca root powder according to the mass ratio of (3-5): (1-1.7), performing enzymolysis through cellulase, then performing common enzymolysis through ficin protease and papain, and performing adsorption and purification through an HPD722 macroporous adsorption resin column. All the components are compatible according to a specific proportion, so that the allergy and skin irritation risks are reduced, skin injury healing is reasonably promoted, and melanin deposition is effectively inhibited.

The invention relates to the technical field of laser, and discloses a laser device capable of outputting different wavelengths and energy and having AI learning, which comprises a laser box, and is characterized in that a laser light source device, an integrated control module and an AI intelligent module are arranged in the laser box, the laser light source device is connected with the integrated control module, and the AI intelligent module is connected with the integrated control module. The integrated control module is connected with the AI intelligent module. The laser device capable of outputting different wavelengths and energy and having the AI intelligent function is simple in structure and easy to implement, can realize multi-wavelength and multi-energy output, meets different application requirements, monitors, feeds back, regulates and controls in time, is equipped with the AI intelligent function, automatically regulates and optimizes laser output, has both safety and accuracy, and is suitable for popularization and application. Potential eye and skin injuries are avoided in medical application, efficiency and performance are improved in industrial application, implementation cost is low, and high economic benefits are achieved.

The invention belongs to the technical field of pressure injury, and particularly relates to a comprehensive prevention and management system for neonatal skin injury. According to the method, the clinical data and the multi-modal physiological parameters are fused, the personalized risk threshold is generated, single risk judgment is avoided, the pertinence and accuracy of prediction are improved, data are collected only in the physiological steady-state period, noise caused by illness state fluctuation or interference factors is effectively reduced, the stability and credibility of risk parameter calculation are improved, and the risk prediction accuracy is improved. The comprehensive risk assessment process is fully automatically executed, when a score exceeds a threshold value, graded early warning and intervention pushing are instantly triggered, the response time from risk identification to intervention is greatly shortened, real-time effect verification is carried out on intervention measures through an intervention feedback module, closed-loop management of risk discovery, intervention, verification and optimization is achieved, missed alarms and invalid intervention are reduced, and the risk assessment efficiency is improved. The system automatically generates a monitoring curve and a historical trend, helps medical staff to visually judge a risk change trend, and supports long-term management and scientific research analysis.

The present application relates to polypeptides and their use in repairing mucosal damage or skin damage, the polypeptides of the present application have no homology with known polypeptides, and can stably exist in vivo and in vitro, have the effect of regulating stem cell proliferation and differentiation to repair mucosal damage or skin damage; and relate to the use of the novel polypeptides to repair mucosal damage or skin damage by regulating stem cell proliferation and differentiation, and the use for preventing, alleviating or treating gastrointestinal diseases.

The application provides a drying method of Chuanxiong medicinal material and application of Chuanxiong or its extract in preparation of an external medicine for treating atopic dermatitis. The drying method of Chuanxiong medicinal material improves Chuanxiong processing efficiency, shortens processing period, obtains by-product Chuanxiong extract in addition to preparation of decoction pieces, reduces energy consumption and lowers production cost. The Chuanxiong essential oil and Chuanxiong extract are both composed of small molecule components, have good affinity to skin, are absorbed through skin quickly, can quickly relieve symptoms such as itching and skin damage caused by atopic dermatitis, and are natural, safe and free of side effects. Meanwhile, the small molecule components contained in the Chuanxiong essential oil and Chuanxiong extract have good lipophilicity, have softening effect on the thickened stratum corneum caused by atopic dermatitis, and are more conducive to drug absorption. In addition, the Chuanxiong essential oil and Chuanxiong extract are simple to prepare and low in price.