412 results about "Ulcer care" patented technology

The present invention is directed to drug dosage forms that release an agent that raises the pH of a patient's gastrointestinal tract, followed by a non-steroidal anti-inflammatory drug. The dosage form is designed so that the NSAID is not released until the intragastric pH has been raised to a safe level. The invention also encompasses methods of treating patients by administering this coordinated release, gastroprotective, antiarthritic/analgesic combination unit dosage form to achieve pain and symptom relief with a reduced risk of developing gastrointestinal damage such as ulcers, erosions and hemorrhages.

The present invention provides a method of treating a leg ulcer comprising contacting the leg ulcer with a collagen biofabric. The leg ulcer may be a venous, arterial, diabetic or decubitus (pressure) ulcer. The invention further provides kits comprising one or more pieces of collagen biofabric for the treatment of a leg ulcer.

There is provided herein a sensor for use in patient monitoring, wherein the level of patient activity in a chair or bed is tracked to determine whether or not that patient has exhibited sufficient activity to merit eliminating a scheduled assisted relocation to a new position. The instant device senses the time since a patient last relocated into a different sitting or lying position. If the patient has not moved during some predetermined time period, the nursing staff will be notified that it is time to manually reposition the patient. On the other hand, if the patient has significantly changed position, the device will not signal to the caregiver that a move is necessary, thereby eliminating the need in some cases to rouse the patient from an otherwise sound sleep.

A nasal cannula apparatus is provided for use by patients desiring a comfortable arrangement. The nasal cannula apparatus is particularly suited for long-term oxygen users, for extended wear in both standing, resting and supine positions. The nasal cannula apparatus has headgear and retainers for holding the gas supply tubes, which are adjustable to allow fast and easy adjustment to size. The headgear and retainers allow the cannula tubes to be held in a position which prevents skin discomfort and irritation, and which promotes healing of such irritation, injuries and sores.

Methods and devices are disclosed for detecting vulnerable atherosclerotic plaque, or plaque at risk of reducing blood flow in a vessel, by identifying a region of elevated temperature along a living vessel wall. The disclosure that human atherosclerotic plaque with measurable temperature heterogeneity has the morphological characteristics of plaque that is likely to ulcerate provides a new and sensitive technique for detecting and treating these dangerous plaques before myocardial infarction and its consequences occur. The disclosed methods are advantageous over conventional plaque detection techniques because they are capable of differentiating between those plaques that are at great risk of rupture, fissure, or ulceration, and consequent thrombosis and occlusion of the artery, and those that are not presently at risk. Infrared heat-sensing catheters useful for identifying potentially fatal arterial plaques in patients with disease of the coronary or other arteries are also described. In some embodiments a coherent infrared fiber optic bundle is employed to radially and longitudinally explore a luminal wall to identify inflamed, heat-producing, atherosclerotic plaque. Certain other methods and devices are disclosed which are particularly suited for non-invasively identifying and then monitoring the progression or amelioration of an inflamed plaque in a patient, and for monitoring for onset of inflammation in an implanted arteriovenous graft. Also disclosed are thermocouple basket catheters and thermistor basket catheters which are also capable of detecting temperature heterogeneity along a vessel wall.

The present invention pertains to a system and method for monitoring a human foot by measuring pressures applied to regions of the foot or by measuring another tissue-health related condition. A light source in the 400 nm to 1400 nm range and a detector can be embedded in a wearable article that contacts tissue while in use, spaced 200 μm to 1 cm apart, and measure a tissue hemoglobin condition. A pressure-sensing array may be read by a low-power control circuit, and a power source can be incorporated in the article. An external processing unit wirelessly coupled to the control circuit can relate pressures measured with counts that are associated with injury risk, and an alert system can notify a patient if the counts exceed a predetermined threshold. A relationship between pressure experienced by a region of tissue and the risk of ulcer development in that region may be derived.

The invention relates to an alginate-based hydrogel dressing and a preparation method thereof, and belongs to the technical field of medical supplies. Raw materials of the invention are a compound of sodium alginate or other alginates and a thickener, a moisturizer and other functional matters, are subjected to swelling dosing, pre-crosslinking, film coating, spray crosslinking, constant-temperature crosslinking plasticizing and film-covering shear forming, and are then prepared into a three-dimensional water-containing grid structure through covalent cross-linking and ion cross-linking. The medical hydrogel dressing is a topical gel dressing, has good moisturizing performance, toughness and adhesion, is mainly suitable for superficial skin damage, such as cut wound, lacerated wound, scratch, burns, suture wounds and the like, protects skin wound healing of a patient, has effects of easing pain, inhibiting bacteria, resisting inflammation, keeping the wound moist, promoting wound healing, and improving the wound repairing quality, is more suitable for treating bedsore wounds, ulcer wounds and other sites hard to be bound after a surgery, can also be used for non-wound sites, and plays a role of moisturizing.

The present disclosure is directed to drug dosage forms that release an agent that raises the pH of a patient's gastrointestinal tract, followed by a non-steroidal anti-inflammatory drug. The dosage form is designed so that the NSAID is not released until the intragastric pH has been raised to a safe level. The disclosure also encompasses methods of treating patients by administering this coordinated release, gastroprotective, antiarthritic/analgesic combination unit dosage form to achieve pain and symptom relief with a reduced risk of developing gastrointestinal damage such as ulcers, erosions and hemorrhages.

[Problems] To provide a novel external agent for treatment of skin ulcer which has an excellent healing effect on intractable skin ulcer such as bedsore, diabetic skin ulcer and ischemic skin ulcer.

[Means for Solving Problems] The agent is characterized in that it comprises a composition containing at least one selected from the group consisting of granulocyte colony stimulating factor (G-CSF), stromal cell-derived factor-1 (SDF-1) and CD41-positive cells, and a hydrophilic high molecular substance.

A system and procedure for preventing and enhancing healing of Decubiti ulcers on patients, comprising the steps of placing the patient on a web adapted to support the patient, the web having a patient contacting portion and a non-patient contacting portion, the web having an opening through the web, positioned so that the opening surrounds the ulcer and prevents contact of the web with the ulcer, and using a web support system adapted to support the web by attachment only to the non-patient contacting portion, to solely support the web with a patient on it. The procedure may also include a step wherein a rocking device is used that acts through the web support system to selectively tilt the web and thereby to tilt the patient on the patient contact portion of the web, so that the pressure between the patient and the web is cyclically altered.

The invention relates to the use of Epidermal Growth Factor (EGF) in a preferably-injectable pharmaceutical composition which is administered by means of infiltration into and around chronic cutaneous ischaemic lesions in order to prevent diabetic foot amputation. Said composition can be administered to recently-created surgical surfaces damaged by the effect of acute reperfusion with oxygenated blood following prolonged ischaemia, thereby preventing further surgical procedures and favouring the preservation of the extremity. The aforementioned composition can be used to improve (i) the cell microenvironment, thereby increasing the reparative and defensive capacity and viability of the is tissues and (ii) the cicatrisation of cutaneous ischaemic lesions, thereby stimulating cell proliferation. The invention is suitable for use in human, veterinary and experimental medicine, specifically in vascular angiology and surgery, dermatology, burn treatment and reconstructive surgery and geriatric medicine. Said composition can be used for recalcitrant ulcers which are associated with lesions in the macro and/or microvasculature, patients with inadequate lymphatic and/or venous return and ulcers or other lesions which are difficult to cicatrise and/or heal.

The invention discloses the discovery that a pharmaceutical composition containing complex carbohydrates and natural or synthetic essential oils can work effectively as a topical pharmaceutical composition. Such pharmaceutical compositions reduce inflammation, assist in wound healing, protect against bruising, relieve itching, relieve pain and swelling and treat topical bacterial infections such as acne and decubitus ulcers. Such pharmaceutical compositions can be administered to mammals including humans. Also included in this invention are methods to deliver topically applied macromolecules into the tissue of mammals and methods of blocking the adhesion cascade.

An application of the montmorillonite nanoparticles in preparing the medicine for treating the ulcer in digestive tract, regurgitation of stomach and esophagus, esophagitis, gastritis, colitis, acute diarrhea, chronic atrophic gastritis is disclosed. Its composite medicine is also disclosed.

The invention discloses new dihydroiso-coumarin glucoside compounds shown in a formula I, which are extracted and separated from Periplaneta americanna medicinal materials. Through mouse auricle swelling tests, rat granulation tissue hyperblastosis tests and the like, results show that the compounds have effects of resisting inflammation, promoting wounds to heal and the like; and the compounds can be used for preparing medicines for treating inflammation, ulcers, wounds, incised wounds, fistula, burn, scalding and the like, particularly medicines for preventing and treating diseases related to inflammation resistance, promotion of granulation tissue hyperblastosis, wound healing and the like, and have high clinical application value. The invention provides a preparation method for the compounds shown in the formula I.

The invention relates to prostaglandin microemulsion-gel preparation and a preparation method thereof. The preparation comprises prostaglandin E1 or the derivative thereof, oil, emulsifier, assistant for emulsifying agent, gel substrate and water, and also possibly comprises a permeation accelerator, a preparation stabilizer, an antioxidant and antiseptics. The preparation has the advantages of good percutaneous permeability, no stimulation to skin and mucous membrane, simple preparation technique and stable quality, the preparation can be used for treating diseases such as ulcer of limbs caused by erectile dysfunction and chronic arterial occlusion and rest pain of limbs caused by microcirculatory disturbance.

The present invention provides thin-film forming compositions comprising an antiseptic (e.g., povidone iodine, chlorhexidine, or octenidine), a non-aqueous solvent, and a film-forming material dissolved in the non-aqueous solvent, wherein the composition yields a continuous and flexible protective film upon substantial removal of the solvent. The compositions are useful for the treatment and prevention of infections in wounds, ulcers (e.g., decubitus ulcers and stasis ulcers), cuts, or burns, or against infections from bacterial, mycobacterial, viral, fungal, or amoeba causes, as well as for prevention of such infections in appropriate clinical settings (e.g., as liquid bandages or dressings). Additionally, the compositions of this invention are also useful for the treatment of infections and as a disinfectant skin preparation for pre- and/or post-surgical operations.

The invention discloses a medicinal composition for treating skin injury and ulcer diseases, and belongs to the field of Chinese medicament. The medicinal composition consists of collagen and Chinesemedicaments for activating blood and dissolving stasis such as angelica, Szechuan lovage rhizome, salvia root and the like which are prepared into a plurality of dosage forms by matching the prior art. The technology overcomes the defects that the prior common preparations for the trauma department have extremely slow response, longer treatment course, adhesion with the skin, influence on scab cicatrization and the like, has quick and remarkable treatment effect on various skin diabrosis diseases such as mechanical wound, burn/scald, bedsore, chronic leg ulcer, diabetic foot or cancerous ulcerand the like, and can greatly shorten the required time for wound healing and tissue repair and relieve pains of patients.

The invention relates to the technical field of traditional Chinese medicine application, in particular to a traditional Chinese medicine composition with the oral health efficacy, overcoming the defects that the prior oral health products have single and unfavorable curative effect. The traditional Chinese medicine composition with the oral health efficacy comprises the following medicinal materials by weight percentage: 10 to 20 of cimicifuga foetidae, 10 to 20 of angelica dahurica, 5 to 15 of asarum, 10 to 20 of mint, 10 to 20 of nutgall, 10 to 25 of cortex lycii radicis, 5 to 15 of pepper and 2 to 10 of borneol which are prepared into product medicament forms, such as mouthwash, toothpaste, chewing gum, spray, paste, cream, chewing tablets, lozenges, and the like. Compared with the prior art, the product can effectively prevent canker sore and has the efficacy of rapidly curing the canker sore.

Disclosed herein are insoles useful for treating skin injuries on a foot, for instance ulcers. The insoles are customizable for each patient's foot and can include various portions of differing softness, depending on the needs of the patient. For instance, it can be beneficial for certain sections of the foot to contact a firmer material, whereas other sections contact a softer material. Some, or all, of the materials can include one or more biofidelic skin simulant materials. Thus, various implementations include one or more regions that can include the same or different materials. For example, a custom insole can include a heel support region, a midfoot support region, and a forefoot support region, and the support regions can be subdivided into medial and lateral support regions or toe regions. One or more regions may have a custom isolation segment to prevent the progression of ulcers and/or expedite wound healing.

A heel supporting and protective boot for bed-ridden patients who may otherwise develop pressure sores on their heel. The body of the boot is comprised of a fiber and angled foam combination heretofore not used. The boot additionally has sewn tube holes on both sides allowing for use of medical tubing such as with a sequential compression pump. The inner portion material of the boot is a soft liner fabric which is antibacterial and absorbs moisture. The outer portion material of the boot is a fabric with fluid resistance. Further, the boot has a soft fiber-filled flap covering the shin portion of the leg to prevent pressure on the dorsal side of the lower leg. The boot additionally has a foot-position strap sewn and placed to the bottom of the boot running along both sides of the boot and attaching at the top of both sides of the upper boot to assist with the prevention of foot drop. Said invention further uses an opening at the heel which allows the heel to remain exposed to air as a result of proper elevation and cushioning created by the unique combination of fiber and angled foam in the body of said device. The elements incorporated address important factors in preventing or allowing healing of heel sores, or enhancing the curing of existing ulcers while minimizing chances of foot drop and minimizing chances of new pressure points. The fiber/foam combination, dual fabric content, shin flap, tubing holes, foot position strap and open heel design all work together to ensure proper healing and prevention of decubitis ulcers.