133 results about "Amputation" patented technology

Systems and methods according to the present invention relate to a novel peripheral nerve stimulation system for the treatment of pain, such as pain that exists after amputation.

Systems and methods according to the present invention relate to a novel peripheral nerve stimulation system for the treatment of pain, such as pain that exists after amputation.

A gait assistive system designed to assist with the therapeutic treatment of subjects who have difficulty in walking, specifically those with a lack of sensation due to nerve damage or amputation, who are unable to tell when the foot makes contact with the floor. The system includes a removable insole placed inside the shoe which proportionally senses touchdown of the limb. The sensed touchdown is communicated to a transmitter and subsequently to a remotely positioned receiver to provide a desired bio-feedback of the sensed touchdown. The system can also include a second remotely located receiver that can be used to facilitate set up and / or adjustments of the system.

The invention provides an artificial limb control method which comprises the following steps: acquiring a bioelectric signal; extracting feature information of the bioelectric signal; identifying action types according to the feature information; analyzing the feature information by using a linear distinguish and analytical method and identifying the action types according to pre-stored train results, training an action classifier by a train program module; and controlling an artificial limb to complete corresponding actions according to the action types. By adopting the artificial limb control method, an artificial limb user can naturally and directly select and perform various different physical actions that the user intends to complete just like before amputation. The control technology based on action type identification can realize intuitive control of the myoelectric artificial limb so as to realize natural and intuitive control of the multifunctional artificial limb, thus enhancing use convenience of the artificial limb. In addition, the invention further provides an artificial limb control system.

The invention discloses an active-passive type two-degrees-of freedom ankle joint prosthesis, comprising a carbon fiber energy storage sole, a motor, a speed reducer, a motor fixing supporting seat, a belt pulley transmission device, a carbon fiber pipe, a ball screw, an energy storage springs, joint bearings, energy storage rubber rings and joint supporting seats, wherein the carbon fiber energy storage sole is connected with the carbon fiber pipe through the joint supporting seats; the motor fixing supporting seat is connected with the carbon fiber pipe through an active pin; the motor is fixedly arranged on one end of the motor fixing supporting seat; the ball screw is fixedly arranged on the other end of the motor fixing supporting seat; two ends of the motor fixing supporting seat are connected by the belt pulley transmission device; the energy storage springs areis connected with a ball screw nut; and the energy storage rubber rings are connected with the joint bearings and the joint supporting seats through a shaft. The ankle joint prosthesis provided by the invention not only can completely provide required energy for human gait, but also can adapt to various landforms; in addition, the ankle joint prosthesis can completely imitate movement angles of a human ankle joint on a sagittal plane or a coronal plane; and therefore, the normal walking requirement of an amputation patient can be satisfied better.

The invention relates to the use of Epidermal Growth Factor (EGF) in a preferably-injectable pharmaceutical composition which is administered by means of infiltration into and around chronic cutaneous ischaemic lesions in order to prevent diabetic foot amputation. Said composition can be administered to recently-created surgical surfaces damaged by the effect of acute reperfusion with oxygenated blood following prolonged ischaemia, thereby preventing further surgical procedures and favouring the preservation of the extremity. The aforementioned composition can be used to improve (i) the cell microenvironment, thereby increasing the reparative and defensive capacity and viability of the is tissues and (ii) the cicatrisation of cutaneous ischaemic lesions, thereby stimulating cell proliferation. The invention is suitable for use in human, veterinary and experimental medicine, specifically in vascular angiology and surgery, dermatology, burn treatment and reconstructive surgery and geriatric medicine. Said composition can be used for recalcitrant ulcers which are associated with lesions in the macro and / or microvasculature, patients with inadequate lymphatic and / or venous return and ulcers or other lesions which are difficult to cicatrise and / or heal.

A method for creating a flexible sleeve member for an amputation stump. The sleeve member is made of a thermoplastic elastic and transparent material. The sleeve member is shaped after a flexed limb, for instance a knee, which makes it easier to avoid foldings of the sleeve, which would otherwise be obtained at the back of the knee when a person wearing the prosthetic device sits down. By means of the sleeve member according to the invention, comfort is improved for a person wearing such a prosthetic device.

The invention relates to a special bed for amputation surgery. The bed comprises a bed board part, a second hemostasis part, an amputation part and two walking parts and is characterized in that one second slider of the amputation part is glidingly mounted in a first dovetail groove in the left side of the bed board part, and one third gear of the amputation part is meshed with a first rack on the left side of the bed board part; upper surfaces of bottom plates of first parallel mechanisms of the two walking parts are mounted two round fixing seats on the lower surface of the bed board part respectively; when a patient requiring amputation lies on a bed board of the bed board part, the height of the bed board part is adjusted through six tenth hydraulic cylinders, the position of the bed is adjusted through eight wheels, so that a doctor can more conveniently observe the patient and observe the patient at a good angle during the amputation surgery, and accidents can be timely handled once occurring.

An externally-powered prosthesis mechanism usable with persons with amputations at or proximal to the level of the metacarpophalangeal joint, as well as persons with high-level amputations. The prosthesis mechanism includes a grasping mechanism including a mechanically operable finger member and a mechanically operable thumb member kinematically linked to the finger member such that the grasping mechanism is disposed in respective opened and closed configurations when the finger member is respectively moved away from and toward the thumb member. The prosthesis mechanism further includes a drive system extending tangentially with respect to the grasping mechanism and including a motor operatively connected to drive at least one planetary gear stage, which is operatively connected to drive the grasping mechanism to the opened configuration when the motor is driven in a first direction and further drive the grasping mechanism to the closed configuration when the motor is driven in a second opposite direction.

A system designed to assist with the therapeutic treatment of subjects who have difficulty in walking, specifically those with a lack of sensation due to nerve damage or amputation, who are unable to tell when the foot makes contact with the floor. The system consists of: 1. A removable insole placed inside the shoe which proportionally senses touchdown. 2. A miniature wireless transmitter which can be worn unobtrusively on the shoe. 3. A miniature wireless receiver with tone generator which feeds an earpiece worn by the user. 4. A separate wireless receiver used by the therapist to monitor the same signal received by the user, in order to facilitate initial set-up and adjustments.

The present invention is directed to a specialized method of treating a severe diabetic ulcer that penetrates the subcutaneous fat layer of a patient. The method comprises the steps of: administering a treatment session to a diabetic patient having a severe diabetic ulcer, the treatment session comprising at least three pulsed electromagnetic fields (PEMF) applications, PEMF applications 1, 2, and 3, and at least two intermittent compression therapy (ICT) applications. The PEMF application and ICT therapy settings address specific factors that are necessary to induce healing of the diabetic ulcer and prevent amputation. In a preferred embodiment, the treatment session further comprises the step of applying a dressing having a silver and / or honey anti-infection composition thereon to the ulcer area to impede microbial growth in the ulcer area. In another embodiment, the method includes the step of applying ultrasound to the ulcer area for a time sufficient to inhibit microbial growth.

The present invention is directed to a specialized method of treating a severe diabetic ulcer that penetrates the subcutaneous fat layer of a patient. The method comprises the steps of: administering a treatment session to a diabetic patient having a severe diabetic ulcer, the treatment session comprising at least three pulsed electromagnetic fields (PEMF) applications, PEMF applications 1, 2, and 3, and at least two intermittent compression therapy (ICT) applications. The PEMF application and ICT therapy settings address specific factors that are necessary to induce healing of the diabetic ulcer and prevent amputation. In a preferred embodiment, the treatment session further comprises the step of applying a dressing having a silver and / or honey anti-infection composition thereon to the ulcer area to impede microbial growth in the ulcer area. In another embodiment, the method includes the step of applying ultrasound to the ulcer area for a time sufficient to inhibit microbial growth.

The invention provides a hand and foot bone defect implant which comprises a defect compensation body and two supporting bodies. The defect compensation body comprises a central rod and an outer sleeve fixedly arranged on the central rod in a sleeving mode. The two ends of the central rod can be inserted in medullary cavities of broken bone on the two sides respectively. The end faces of the two ends of the outer sleeve can be connected with fracture surfaces of the broken bone on the two sides respectively. Cavities used for containing filler are formed in the end faces of the two ends of the outer sleeve. At least one part of the surface of the cavity on each end face is attached to the surface of cortical bone of the corresponding connected broken bone so that the corresponding filler can make contact with the cortical bone. The two supporting bodies are connected with the ends of the central rod respectively. The supporting bodies can make contact with the inner walls of the medullary cavities to support the central rod when the two ends of the central rod are inserted in the medullary cavities of the broken bone. By means of the hand and foot bone defect implant, hand and foot bone defect injuries can be repaired, and therefore the original length of the broken bone can be kept, the risk of amputation is avoided, and part of functions can be kept.

The invention provides a traditional Chinese medicine for curing diabetic foot, in particular a prescription curing diabetic feet of patients having different courses of the disease and different symptoms by stages. The traditional Chinese medicine is prepared from astragalus root, leatherleaf milletia, white peony root, cassia twig, achyranthes root, red sage root, mulberry twigs, Chinese angelica root, licorice, chuanxiong rhizome, ricepaper pith, asarum herb, sweetgum fruit, dried ginger, prepared rehmannia root, antler gelatin, Chinese ephedra, white mustard seed, Chinese date and other Chinese herbs. The prescription has the advantages that the price is low, the applicability is high, no toxic or side effects are caused, and the like. Successful development of the traditional Chinese medicine fills the gap in the field of medicament for curing diabetic feet, and the traditional Chinese medicine is proved to have good effects through clinical application. When in use, the traditional Chinese medicine can be selectively used according to medical histories and symptoms of the patients, so that symptomatic treatment is realized, the traditional Chinese medicine brings good news for the diabetic foot patients, the disease can be relieved without amputation, and the suffering of 'sugar poison' is eliminated.

The invention discloses a medicament for treating diabetic complications and a preparation method thereof. The medicament is mainly prepared from astragalus, polygonum orientale, gypsum, honeysuckle, figwort root, szechwon tangshen root, Chinese angelica, rehmanniae praeparatum, cassia bark, Indian buead, large-headed atractylodes rhizome, white paeony root, plantain seed, raw cinnamomvine, notoginseng root and liquorice root according to a certain weight ratio, and can be prepared into any common formulations. The medicament of the invention has obvious curative effect on the treatment of the diabetic complications and obvious effect of antidiabetics, promotes blood circulation, absorbs extravasated blood of fundus quickly, rehabilitates blood vessels and restores vision. In addition, for patients who suffer from gangrene, the medicament can eliminate polyneuropathy, invigorate podiatric thrombus quickly to form normal blood circulation and cure wounds, and the patients do not need amputation; and the diabetic complications become effective completely within one month, the cure rate of fundus hemorrhage (before laser treatment) within three months is 88 percent, the cure rate of nephropathy is 82 percent, the cure rate of the polyneuropathy is 85 percent, the cure rate of the gangrene is 89 percent, and the comprehensive cure rate of other symptoms is 84 percent. Until now, the diabetic complications are difficult to relapse from the follow-up period, and the medicament is well received by the patients.

The invention relates to the use of Epidermal Growth Factor (EGF) in a preferably-injectable pharmaceutical composition which is administered by means of infiltration into and around chronic cutaneous ischaemic lesions in order to prevent diabetic foot amputation. Said composition can be administered to recently-created surgical surfaces damaged by the effect of acute reperfusion with oxygenated blood following prolonged ischaemia, thereby preventing further surgical procedures and favouring the preservation of the extremity. The aforementioned composition can be used to improve (i) the cell microenvironment, thereby increasing the reparative and defensive capacity and viability of the is tissues and (ii) the cicatrisation of cutaneous ischaemic lesions, thereby stimulating cell proliferation. The invention is suitable for use in human, veterinary and experimental medicine, specifically in vascular angiology and surgery, dermatology, burn treatment and reconstructive surgery and geriatric medicine. Said composition can be used for recalcitrant ulcers which are associated with lesions in the macro and / or microvasculature, patients with inadequate lymphatic and / or venous return and ulcers or other lesions which are difficult to cicatrise and / or heal.

This invention relates generally to an index map comprising both pressure and perfusion information from a diabetic patient foot for the purpose of treatment. The index map may also be a map of perfusion and / or metabolism of the tissue (reflecting oxygen delivery and oxygen extraction), obtained by thermal imaging, hyperspectral imaging, or duplex ultrasound, MRA, CT or laser Doppler imaging. This information aids treatment in prevention of diabetic foot ulceration and amputation and in treatment of tissue compromise to prevent tissue loss in other body regions.

The present invention provides methods for treating critical limb ischemia (CLI), including increasing wound healing, decreasing wound size, increasing survival-free amputation, preventing amputation, preventing or delaying de novo gangrene, increasing survival probability, and preventing or delaying death, in subjects who prevent a vascular occlusion that cannot be resolved by using a standard method of revascularization, i.e. a subject with “no-option” CLI. Methods of the invention include administering to a subject with no-option CLI an isolated cell composition for tissue repair comprising a mixed population of cells of hematopoietic, mesenchymal and endothelial lineage, wherein the viability of said cells is at least 80% and the composition contains: a) about 5-75% viable CD90+ cells with the remaining cells in said composition being CD45+; b) less than 2 μg / ml of bovine serum albumin; c) less than 1 μg / ml of a enzymatically active harvest reagent; and d) substantially free of mycoplasma, endotoxin, and microbial contamination.

The present invention extends to a stemmed amputation implant. In some embodiments, a dual stemmed implant includes a base plate and two intramedullary rods extending from the proximal side of the base plate. The two intramedullary rods are configured for insertion into corresponding intramedullary bone canals reamed into remaining portions of amputated bones, such as, for example, a tibia and fibula or an ulna and radius. The position of the intramedullary rods relative to one another is configured to maintain appropriate separation between amputated bones when the first intramedullary rod and the second intramedullary rod are inserted into the amputated bones. In some embodiments, a hollow tube replaces one or more of the intramedullary rods. A hollow tube can be configured to cover the exterior of a bone, such as, for example, the fibula, when the bone is not stable enough for intramedullary fixation.

The invention relates to a bionic mechanical prosthetic hand driven by a wrist joint, comprising a wrist module, a metacarpal joint module and a plurality of finger mechanisms. Each finger mechanism comprises a first knuckle, a second knuckle, a third knuckle, a facet joint knuckle connecting rod and a large joint knuckle connecting rod, wherein one end of the first knuckle is respectively connected with the facet joint knuckle connecting rod and the second knuckle, one end of the second knuckle is respectively connected with the large joint knuckle connecting rod and the third knuckle, one end of the third knuckle is connected with a through-going shaft, one end of the large joint knuckle connecting rod is connected with the driving rod of the wrist joint, the other end is connected with the facet joint knuckle connecting rod; and the wrist module comprises a wrist joint drive rod, a wrist connecting block and a wrist fixing ring, the wrist fixing ring fixed on the wrist is connected with the wrist connecting block rotatably through a connecting shaft. The prosthetic hand not only has the flexion and extension function of human fingers, and has grasping and kneading functions. The device is small and exquisite, and the appearance is close to the size of human fingers, so that the bionic mechanical prosthetic hand is suitable for patients with metacarpal amputation or high phalanx amputation to wear.

The invention relates to the field of biological preparations, in particular to a preparation method of stem cell exosomes and a novel application thereof. The method comprises the steps of extractionof mesenchymal stem cell exosomes, percutaneous transluminal coronary angioplasty, and stem cell exosome transplantation, and can be used for treating diabetic foot. The novel application of exosomescan accurately and effectively improve the microcirculation of diabetic foot, promotes angiogenesis, reconstructs capillary network, reduces occlusion of blood vessel restenosis, reduces amputation rate, and provides survival rate.

An electrical-stimulation perception feedback system for perception feedback of an artificial limb hand is designed based on an induced finger-feeling area of the skin of an amputation stump and comprises a pressure sensor module, a digital signal processing module and an electrical-stimulation module. The pressure sensor module acquires a pressure signal of the artificial limb hand and transfers the pressure signal to the digital signal processing module, the digital signal processing module processes the pressure signal and outputs a control signal to the electrical-stimulation module, the electrical-stimulation module performs real-time electrical stimulation according to the control signal and comprises an electrical stimulator and an electrode, and the electrode is arranged in the induced finger-feeling area of the skin of the amputation stump. The electrical-stimulation perception feedback system achieves perception feedback of artificial limb fingers and can stimulate the induced finger-feeling area of the corresponding part of an amputee in an electrical-stimulation feedback mode to produce real-time touch sense feedback.

The invention provides an artificial limb system aiming at upper-limb high amputation patients. The artificial limb system comprises a receiving mechanism, an elbow joint, a wrist joint, a mechanical arm and a control system, wherein the receiving mechanism and the elbow joint are connected through a connecting flange; the elbow joint and the wrist joint are connected through a connecting rod, and a cavity is reserved between the elbow joint and the wrist joint; the elbow joint is used for driving the wrist joint and the mechanical arm to move in the space; the wrist joint is used for adjusting the posture of the mechanical arm in grabbing the object; the mechanical arm comprises 5 fingers, and the fingers can move independently; the control system is used for controlling the receiving mechanism, the elbow joint, the wrist joint and the mechanical arm. Compared with the prior art, the artificial limb system has the beneficial effects that the elbow joint is driven by a brushless motor and adopts a harmonic reducer, the structure is compact, and the noises are small. The wrist joint adopts a conducting ring, and thus a power supply and a communication channel are provided for the power supply of a tactile feedback sensor and a mechanical arm controller.

The present invention extends to a stemmed amputation implant. In some embodiments, a dual stemmed implant includes a base plate and two intramedullary rods extending from the proximal side of the base plate. The two intramedullary rods are configured for insertion into corresponding intramedullary bone canals reamed into remaining portions of amputated bones, such as, for example, a tibia and fibula or an ulna and radius. The position of the intramedullary rods relative to one another is configured to maintain appropriate separation between amputated bones when the first intramedullary rod and the second intramedullary rod are inserted into the amputated bones. In some embodiments, a hollow tube replaces one or more of the intramedullary rods. A hollow tube can be configured to cover the exterior of a bone, such as, for example, the fibula, when the bone is not stable enough for intramedullary fixation.

Devices and methods for removing tissue, which causes minimal pain or scarring. A hemostatic clamp having two arms with juxtaposeablefaces, can compress tissue between the faces of the arms so as to fuse a portion of the tissue therebetween. A locking mechanism maintains pressure on the arms until the skin is fused to create a skin tab. The unwanted tissue, such as a polydactyl digit, skin tag, or the like, can be excised with the clamp in position. When the locking mechanism is disengaged and the clamp is removed, the fused skin tab inhibits bleeding and the removal of the digit encourages any remaining underlying nerves to withdraw from the area of amputation. A related device can be used as a castration clamp to externally compress testicular-related tissues, such as ductiles, nerves, and blood vessels leading to the testicles, to castrate an animal. The castration clamp provides a quick, bloodless technique that eliminates the need for open wounds, which are subject to infection.

The invention relates to a traditional Chinese medicine composition for treating diabetes mellitus. The traditional Chinese medicine composition contains the following effective constituents: bamboo shoots, cassia barks, cape jasmine, Garter snakes, sea-buckthorn, radix angelicae and fructus citri. The traditional Chinese composition is specially used for treating complications of diabetes mellitus, such as foot diseases in diabetes mellitus, diabetic nephropathy, diabetic cardiopathy and eye diseasse in diabetes mellitus. The traditional Chinese medicine composition has the effects of dissolving thrombus, dredging and softening blood vessels and regulating blood sugar and can obviously improve lower limb vascular occlusion, renal function injuries, heart diseases and eye ground injuries caused by blood vessel pathological changes and diabetic neuropathy of diabetes mellitus patients, prompt the healing of diabetic foot ulcers, avoid the amputation of the patients, improve numb, cold, swelling, expanding and painful symptoms of lower limbs of the patients and improve the symptoms of yang deficiency, body cold and weak physique.

The invention relates to a flexible powered below-knee prosthesis which is characterized by comprising a prosthesis foot and a prosthesis shank. The prosthesis foot comprises an upper foot made of carbon fiber boards and a heel elastic sheet. The front of the heel elastic sheet is disposed at the middle bottom of the upper foot. An elastic moving space is arranged between the rear of the heel elastic sheet and the upper foot. A support is disposed on the top surface of the upper foot. The prosthesis shank comprises a shell which simulates the shape of a human shank. A motor is fixed in the shell. An output end of the motor is connected with a screw. The screw is connected with a screw sleeve through threads. The bottom end of the screw sleeve penetrates out of the shell and is connected to the top surface of the upper foot. A support column is disposed on the support of the upper foot. The flexible powered below-knee prosthesis is light, flexible, ingenious in ankle design, and widely applicable to various amputation patients.

The present invention is related to the use of topical formulations that contain epidermal growth factor encapsulated in or associated to deformable or conventional liposomes to be applied on the surface of and around chronic ischemic skin lesions. The formulations of the present invention, in contrast with the previous art, are useful because they provide a high bioavailability of EGF in the tissue deep below the lesions and for preventing diabetic foot amputation.

The invention provides a lower limb prosthesis road condition recognition method based on surface electromyogram signals. The method comprises the following steps of 1, collecting and preprocessing the lower limb surface electromyogram signals of a thigh amputation patient under different road conditions; 2, extracting a characteristic value sample set of road condition recognition of the preprocessed lower limb surface electromyogram signals; 3, optimizing classification parameters of the extreme learning machine through a backbone particle swarm algorithm to obtain an optimal ELM classifier,and realizing lower limb prosthesis road condition identification and classification. According to the lower limb prosthesis road condition recognition method based on surface electromyogram signals,an extreme learning machine classifier is constructed by using the optimal hidden layer node number and the kernel function parameters. The road condition recognition accuracy is high. The backbone particle swarm algorithm has global search capability, is easy to implement and high in search speed. The premature phenomenon can be effectively avoided on the premise of ensuring the accuracy. The road condition recognition accuracy is effectively improved.