American cockroach medicinal composition for curing ulcers or ulcerative inflammation and preparation method thereof

A technology of Periplaneta americana and its composition, which is applied in the field of medicine, can solve the problems of no curative effect and poor curative effect, and achieve the effect of remarkable cure rate, remarkable effect and simple preparation method

Inactive Publication Date: 2010-09-22
耿福能
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, montmorillonite is scattered on oral ulcers, recurrent afluta ulcers, oral lichen planus, oral mucosal damage caused by various reasons (Behcet's disease, herpes simplex, leukoplakia, discoid lupus erythematosus, hand, foot and mouth disease, burns, chemotherapy, etc.) , radiotherapy, etc.), reflux esophagitis, esophageal ulcer, radiation esophagitis, ulcerative colitis, radiation proctitis, diarrhea with mucosal damage, blood in the stool and other diseases have poor curative effect or even no curative effect. The effective cure rate of using montmorillonite powder is about 65-85%.

Method used

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  • American cockroach medicinal composition for curing ulcers or ulcerative inflammation and preparation method thereof
  • American cockroach medicinal composition for curing ulcers or ulcerative inflammation and preparation method thereof
  • American cockroach medicinal composition for curing ulcers or ulcerative inflammation and preparation method thereof

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preparation example Construction

[0028] The preparation method of the Periplaneta americana pharmaceutical composition for the treatment of ulcer or ulcerative inflammation, comprises the following steps:

[0029] 1. Preparation of Periplaneta americana extract:

[0030] a, coarse crushing: the dried Periplaneta americana is pulverized, and the Periplaneta americana coarse powder is prepared for subsequent use;

[0031] b. Soaking: add 3 to 5 times the amount of water for every 100kg of coarse powder, and soak for 0.5 to 2 hours at a temperature of 70 to 78°C to prepare a coarse powder mixture for later use; among them, the preferred solution is: add water The amount is 4 times the amount, the soaking time is 1 hour, and the soaking temperature is 74°C;

[0032] c, three extractions: the coarse powder mixed solution is extracted three times by decocting, and when the coarse powder mixed solution is extracted for the first time, the extraction time is 7 to 9 hours; After adding 2 to 4 times the amount of wat...

Embodiment 1

[0043] Carry out according to the above method, coarsely crush the dried Periplaneta americana, add 300Kg water for every 100Kg coarse powder, soak for 0.5 hours, the temperature is about 70°C, extract three times, the first time is 7 hours; add water 200Kg for the second time, extract 5 hours; add 200Kg of water for the third time, and extract for 3 hours; combine the three extracts, filter, and concentrate the filtrate to a relative density of 1.05-1.08 (70°C), add ethanol with a concentration of 93% w / w to make an alcohol-containing The volume is 40%, 70 ℃ heat preservation and stirring for 20 minutes, let stand for 10 hours, discard the upper layer of grease, filter the lower layer of liquid medicine, the filtrate recovers ethanol, concentrates under reduced pressure to a relative density of 1.15 ~ 1.18 (70 ℃), and concentrates at normal pressure to For the ointment with moisture≤25%, according to the weight ratio of Periplaneta americana extract: montmorillonite powder=0.8...

Embodiment 2

[0045] Carry out according to the above method, coarsely crush the dried Periplaneta americana, add 500Kg water for every 100Kg coarse powder, soak for 2 hours, the temperature is about 78°C, extract three times, the first time is 9 hours; add water 400Kg for the second time, extract 7 hours; add 400Kg of water for the third time, and extract for 5 hours; combine the three extracts, filter, and concentrate the filtrate to a relative density of 1.22 to 1.25 (90°C), add ethanol with a concentration of 97% w / w to make alcohol-containing The amount is 55%, 90 ℃ heat preservation and stirring for 40 minutes, stand still for 14 hours, discard the upper layer of grease, filter the lower layer of liquid medicine, the filtrate recovers ethanol, concentrates under reduced pressure to a relative density of 1.27 ~ 1.30 (90 ℃), and concentrates at normal pressure to For the ointment with moisture≤35%, according to the weight ratio of Periplaneta americana extract: montmorillonite powder=1.2...

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Abstract

The invention discloses an American cockroach medicinal composition for curing ulcers or ulcerative inflammation. The medicinal composition is mainly prepared from an active ingredient mixture prepared by mixing an American cockroach extract and montmorillonite powder. The weight part ratio of the American cockroach extract to the montmorillonite powder is equal to 0.8-1.2:0.5-6. A preparation method of the American cockroach medicinal composition for curing the ulcers or the ulcerative inflammation comprises the following steps of: preparing the American cockroach extract, mixing active ingredients, and preparing medicaments. The medicinal composition has simple preparation method, fully exerts effects of the American cockroach extract, and has obvious effects of effectively curing diseases such as oral ulcers, recurrent aphthous ulcers, oral lichen planus, oral mucosal injury (behcet disease, herpes simplex, leukoplakia, discoid lupus erythematosus, hand-foot-and-mouth disease, scalds, chemotherapy, radiotherapy and the like) caused by various reasons, reflux esophagitis, eophageal ucers, radiation esophagitis, ulcerative colitis, radiation proctitis, and diarrhea, and hematochezia with mucosal injury, and the like.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a Periplaneta americana medicinal composition for treating ulcer or ulcerative inflammation and a preparation method thereof. Background technique [0002] According to literature records, Periplaneta americana is the largest insect in the cockroach family. It is native to South America. Periplaneta americana is a traditional Chinese medicinal material. It is used as medicine with dried and fresh adults. Its nature is salty, poisonous and pungent. , has the functions of dispelling blood stasis, eliminating stagnation, detoxification, diuresis, and detumescence; it is mainly used to treat children with malnutrition, tonsillitis, body mass, carbuncle sores, and centipede and snake bites. [0003] In recent years, with the continuous development of science and technology, after years of research, it has been found that the epidermis of Periplaneta americana contains sclera and chit...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/64A61P1/02A61P1/04A61P1/00A61P1/12A61P7/04A61K33/06
Inventor 耿福能刘彬黄婉怡胡若瑛杜江
Owner 耿福能
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