91 results about "Malnutrition" patented technology

The invention relates to the technical field of nutritional supplements. A traditional fat reducing method mainly comprises dieting, high-intensity exercise, medicine weight losing and the like. However, dieting may lead to malnutrition; high-intensity sports are difficult to insist, and sports injury is easily caused; in order to solve the technical problems, the invention discloses a fat-reducing nutritional composition capable of improving metabolism, and the fat-reducing nutritional composition can be used for solving the technical problems of severe side effects such as tachycardia, insomnia and the like caused by medicine weight loss. The composition comprises the following components in parts by weight: 13-21 parts of a bitter gourd extract, 15-31 parts of a garcinia cambogia extract, 13-17 parts of oat fibers, 17-23 parts of whey protein powder, 7-9 parts of linseed oil, 6-14 parts of a green tea extract, 9-15 parts of a calcium supplement and 15-19 parts of a purple perilla seed extract, and can provide energy for a user, supplement immune globulin, lactoferrin and a calcium source, improve the immunity of the user and improve the immunity of the user. The body metabolism level and immunocompetence are improved, absorption of fat in digestive tracts can be effectively inhibited, storage of fat in the body is reduced, fat consumption is promoted, and the fat reducing effect is achieved.

The invention features polypeptides that include an extracellular ActRIIa variant. In some embodiments, a polypeptide of the invention includes an extracellular ActRIIa variant fused to an Fc domain monomer or moiety. The invention also features pharmaceutical compositions and methods of using the polypeptides to treat diseases and conditions involving weakness and atrophy of muscles, e.g., Duchenne muscular dystrophy, facioscapulohumeral muscular dystrophy, inclusion body myositis, amyotrophic lateral sclerosis, sarcopenia; or cancer cachexia; or metabolic diseases, e.g., obesity, Type-1 diabetes, or Type-2 diabetes.

The invention features polypeptides that include an extracellular ActRIIa variant. In some embodiments, a polypeptide of the invention includes an extracellular ActRIIa variant fused to an Fc domain monomer or moiety. The invention also features pharmaceutical compositions and methods of using the polypeptides to treat diseases and conditions involving weakness and atrophy of muscles, e.g., Duchenne muscular dystrophy, facioscapulohumeral muscular dystrophy, inclusion body myositis, amyotrophic lateral sclerosis, sarcopenia; or cancer cachexia; or metabolic diseases, e.g., obesity, Type-1 diabetes, or Type-2 diabetes.

The invention relates to the technical field of preparation of solid beverages, discloses a preparation method of a ketogenic solid beverage, and provides active high-protein cream powder, protein is modified through hydroxypropyl distarch sodium phosphate under the action of thermal induction and is covalently grafted with fructo-oligosaccharide, a structure with relatively high stability is formed after grafting, and the ketogenic solid beverage is prepared. And protein molecules are not easy to gather together. According to the present invention, the nutrition level of the product is further enriched, the absorption of the nutrition of each component by the human body is easily achieved, the malnutrition problem caused by the ketogenic diet is avoided, the unpleasant taste caused by the addition of fat and protein is avoided through the reasonable matching of the components, and the brewing property of the solid beverage is improved through the improvement of the active high-protein cream powder; the obtained ketogenic solid beverage has the characteristics of balanced nutrition, good flavor, stable property and easiness in storage.

The invention relates to the technical field of breeding, in particular to a livestock head data analysis and management system in the breeding process. Compared with the prior art that a group unified feeding scheme is adopted, individual development differences and environment variables cannot be responded, and double resources are wasted due to insufficient nutrition of high-value livestock and excessive feeding of low-efficiency individuals; according to the scheme, a personalized nutrition demand modeling and formula optimization engine is initiated for the first time, the metabolic state is inversed by analyzing 3D features of the head in real time, the protein energy ratio and the environment compensation coefficient are dynamically calculated, a linear programming solver is linked to generate the lowest-cost formula, the feeding time sequence is adaptively adjusted, and the accurate nutrition supply mode of one animal and one strategy is thoroughly reconstructed; the feed conversion rate and the breeding economic benefit are obviously improved.

The present invention relates to a solid nutraceutical composition for the prevention and treatment of cognitive disorders, consisting of an emulsion and a mixture of seed and oil, all of which are naturally derived. The emulsion contains plukenetia volubilis oil; an extract of plant origin, such as turmeric, pepper or cocoa; an emulsifier selected from lecithin, saponaria or maguey extract, or egg white; the sweetening agent is selected from fructo-oligosaccharide, stevia rebaudiana or maguey extract, Italian bee honey and cane sugar; and air is contained. Seeds and oil include pumpkin seeds and plukenetia volubilis oil. Other ingredients selected from cocoa powder, coconut oil, fruit or seed mass, natural juice and protein are also added. Thus, the nutraceutical comprises 3 to 5 sources of fatty acids, phytosterols and triacylglycerol, 2 to 8 sources of antioxidants, up to 3 sources of hypoglycemic agents, and up to 4 sources of anti-cholesterol and anti-inflammatory compounds. In addition, the nutritional health-care product also contains proteins, vitamins, macroelements, microelements and substances for promoting chewing and swallowing of subjects and patients suffering from cognitive impairment. The nutritional health-care product is suitable for preventing and treating Alzheimer's disease; mental, behavioral and developmental disorders, including depression; neurological, digestive, immune, endocrine and circulatory disorders; cardiovascular, cerebrovascular, infectious, parasitic, neoplastic and blood diseases; fatigue, fatigue and malnutrition.

The invention belongs to the technical field of food nutrition and health, and particularly discloses protein powder for assisting in improving Alzheimer's disease and a preparation method of the protein powder according to the concept of dietary therapy in China, and the protein powder is prepared from the following components in percentage by weight: 35-45% of egg white protein peptide powder and 55-65% of core function compound powder. According to the invention, egg white protein peptide is used as a high-quality matrix, and nine specific medicinal materials including hippocampus, egg yolk phospholipid, egg membrane peptide, walnut, fructus alpiniae oxyphyllae, gastrodia elata, mulberry, sargassum fusiforme, wolfberry, ginkgo leaf, fructus evodiae and dandelion are cooperatively compatible; aiming at seven core pathological links of Alzheimer's disease, such as A beta deposition, Tauopathy, neuroinflammation, oxidative stress, cholinergic deficiency, neurodystrophy and cerebral circulation disorder, a multi-target synergistic effect network is constructed, comprehensive neuroprotection is realized, and tests prove that the space learning and memory ability and the autonomous activity ability can be effectively improved.

The invention relates to a construction method of a model for preoperative evaluation of postoperative complications of hepatic resection. Performing high-order interactive modeling on the plurality of preoperative characteristic variables, and identifying the potential influence of the multi-factor joint effect on the postoperative complications; comprising the interaction between hepatic insufficiency and diabetes and the relationship between preoperative anemia and malnutrition; using a decision tree model to screen out features matched with the complication risk by calculating each variable and interaction item; for the modeling of the nonlinear relationship between the variables, capturing the nonlinear relationship between the variables by adopting a support vector machine (SVM) method; the prediction of the increase of the preoperative liver hardness is in a non-linear relationship with the risk of postoperative complications; constructing a multi-level regression model including hierarchical Bayesian regression, performing risk assessment on different levels including an individual level and a group level, and integrating individual differences and group features of patients; and each layer of model independently evaluates different risk factors, and integrates data of different layers for prediction.

Provided are probiotic compositions and methods of using such compositions for treatment of a spectrum of diseases like malnutrition. The probiotic compositions provided herein have Prevotella copri or engineered strains with genes from Prevotella copri.

The invention relates to a traditional Chinese medicine composition for treating infantile malnutrition, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 7 to 15g of striga asiatica, 8 to 16g of quince, 8 to 15g of raw rhubarb, 9 to 17g of cooked rhubarb, 9 to 16g of vernonia graveolens, 7 to 13g of black semen pharbitidis, 6 to 15g of white semen pharbitidis, 6 to 15g of semen nigellae, 15 to 20g of rhizoma sparganii, 16 to 19g of curcuma zedoary, 9 to 17g of fructus amomi and 10 to 19g of pedicularis muscicola. The traditional Chinese medicine formula disclosed by the invention has the effects of removing food retention, relieving dyspepsia, strengthening the spleen and stomach and expelling parasites, and is a traditional Chinese medicine formula capable of treating the infantile malnutrition, enhancing the immunity of the organism, recuperating the physical function of children and improving the physical quality of the children. The preparation method of the powder prepared from the traditional Chinese medicine formula is inherited for a long time, the compatibility is flexible, the taking modes are various, and the curative effect is remarkable and quick.

The invention discloses PSE-like chicken breast composite gel soft food suitable for people with dysphagia and a preparation method of the PSE-like chicken breast composite gel soft food, and belongs to the field of food processing. The raw materials of the composite gel soft food comprise PSE-like chicken breast, konjac glucomannan and a sodium chloride solution, and the preparation method comprises the following steps: adding a mixed solution of konjac glucomannan and sodium chloride into PSE-like chicken breast, stirring, carrying out heating treatment after uniform stirring, and then cooling to obtain the PSE-like chicken breast composite gel soft food. The prepared food is stable in total protein content, can effectively make up for insufficient intake of meat protein caused by limited feeding of people with dysphagia, and prevents malnutrition; the product texture meets the swallowing requirement, reaches the IDDSI level 5 or level 6 standard, can effectively reduce the risk of food residue and aspiration in the swallowing process, and has nutrition balance and food safety.

The invention relates to the technical field of pet disease treatment, and discloses a microbial preparation for treating inflammatory bowel disease, which is prepared from the following raw materials in parts by weight: 3 to 5 parts of clostridium palustris microecological preparation, 30 to 35 parts of enzymolysis chicken liver powder, 10 to 15 parts of glutamine, 8 to 10 parts of fructo-oligosaccharide, and 1 to 3 parts of beta-1, 3, 4-trimethyl-1, 3-pentanediol monoisobutyrate. The composition is prepared from the following components in parts by weight: 10 to 15 parts of 1, 3-D-glucan, 39.5 to 40 parts of maltodextrin, 0.2 to 0.5 part of silicon dioxide and 0.5 to 1 part of magnesium stearate. According to the microbial preparation for treating the inflammatory bowel disease, diarrhea symptoms of tested pets can be relieved to different extents by preparing the microbial preparation, the intestinal functions of the pets can be directly improved to different extents compared with those before, and due to the fact that the absorption and metabolism functions of intestinal tracts on nutrient substances are improved, the intestinal tracts can be prevented from being damaged. Therefore, malnutrition of the tested pets caused by diseases is relieved for a long time, the weight of the tested pets is increased to different degrees, and the microbial preparation has a positive effect on the pets suffering from the chronic bowel diseases.

The invention provides a protein component composition with special medical application as well as a preparation method and application thereof, and relates to the field of formula food with special medical application. Wherein the protein component composition comprises protein and a sweetening agent; the protein is one or more of hydrolyzed whey protein powder, hydrolyzed casein and albumin peptide. The sweetening agent is one or more of white granulated sugar, glucose syrup, malt syrup, high fructose corn syrup, erythritol, xylitol, maltitol and stevioside. A plurality of components such as a stabilizer, mineral substances and multivitamins can also be added into the protein component composition. The finally obtained composition can be applied to preparation of formula food for special medical purposes, and the content of total protein, hemoglobin, albumin or transferrin in blood of patients suffering from malnutrition or insufficient protein intake is increased.

The invention discloses a system and a method for analyzing and predicting malnutrition of patients with elderly mild cognitive impairment, belongs to the technical field of malnutrition analysis and prediction, incorporates a more comprehensive and systematic index system, and covers potential risk factors, traditional risk factors and laboratory data of the patients with elderly mild cognitive impairment. The comprehensive breakthrough of the research perspective is realized, and the limitation defect of the prior art is broken through. The decision tree model and the logistic regression model are comprehensively compared, a precise malnutrition risk prediction model for the elderly MCI patient is constructed, a reference with practical value is provided for clinical prevention and treatment work, and optimization and perfection of a malnutrition prevention and treatment strategy of the elderly mild cognitive impairment patient are expected to be promoted. According to the method, the defects that in the prior art, analysis of the malnutrition of the elderly mild cognitive impairment patient has limitation, and a traditional prediction model is insufficient in decision making and pertinence aspects of the malnutrition of the elderly mild cognitive impairment patient are effectively overcome.

The invention discloses nutrition powder for vegetarian bird rehabilitation. The formula of the nutrition powder consists of the following components in parts by weight: 19 to 21 parts of compound amino acid, 14 to 15 parts of soybean enzymolysis protein powder, 4 to 6 parts of compound vitamin, 0.8 to 1.2 parts of compound trace element, 31.7 to 33.7 parts of glucose, 4.5 to 5.0 parts of sodium chloride, 3 to 4.0 parts of sodium bicarbonate and 1.8 to 2.2 parts of potassium citrate. The linseed oil microcapsule powder accounts for 14-16 parts by weight, and the powder essence for food accounts for 0.8-1.2 parts by weight. Compared with the prior art, the nutrition powder for the vegetarian birds has the advantages that the nutrition powder for the vegetarian birds is easy to digest by the pet birds and comprehensive in nutrition, nutrition is supplemented for the diseased pet birds, the digestion and absorption burden of the diseased pet birds is relieved, the body weight is effectively increased, and the problem of malnutrition is solved.

The present invention discloses a fish feeding decision method based on Transformer, including: obtaining a fish movement video, using a YOLOv5 model to detect each frame of the image to obtain a detection frame and position information of each fish; calculating the fish center of mass of each frame of the image and normalizing it: constructing a Delaunay triangulation; calculating a weight factor according to a two-dimensional Gaussian normal distribution; obtaining the fish center of mass coordinates; calculating the difference between the fish center of mass of two adjacent frames of the image to obtain a feature vector; processing the Transformer model and inputting a feature vector of a preset length into the model for training; inputting a feature vector of a preset length to be identified into the trained Transformer model to obtain a fish hunger value, comparing the fish hunger value with a preset threshold, and determining whether to feed. The method can avoid excess bait pollution or fish malnutrition, has a low amount of calculation, a high accuracy rate, can realize real-time monitoring of aquaculture, and has good generalization ability.

The application discloses a tumor full-nutrition functional emulsion, which comprises the following components in mass: 10-14% of protein, 7-10% of fat, 12-16% of carbohydrate, 0.01-0.02% of vitamin, 0.5-1.0% of mineral substance and 0.5-1% of food additive, and the balance is water; the protein comprises oyster low-molecular peptide and whey protein at a mass ratio of 2-3:8-12; and the food additive comprises Tween 80 and polyglycerol ricinoleate at a mass ratio of 70-75:20-23. The tumor full-nutrition functional emulsion has a water-in-oil-in-water structure and has freeze-thaw stability; after nutrition support of the tumor full-nutrition functional emulsion, the body's immune regulation ability can be significantly enhanced, the side effect of cyclophosphamide chemotherapy can be reduced, and the body's malnutrition and immunosuppression can be effectively improved.

The invention belongs to the field of nursing science, and particularly relates to an acute exacerbation malnutrition risk prediction model for an old chronic obstructive pulmonary disease patient and a construction method of the acute exacerbation malnutrition risk prediction model, which are used for establishing a rapid and accurate prediction model for acute exacerbation malnutrition risk screening and evaluation of the old chronic obstructive pulmonary disease patient. The invention discloses a model for predicting the risk of acute exacerbation dystrophy of an old chronic obstructive pulmonary disease patient. The risk prediction model is a multivariate Logistic regression model: P =-12.845 + 1.022 * age + 0.339 * ethnic + 0.077 * educated degree + 0.683 * gastrointestinal tract symptom + 0.035 * height-0.126 * body mass index + 1.045 * partial pressure of carbon dioxide-0.077 * chloride ion-0.017 * serum albumin-0.004 * prealbumin + 0.005 * hypersensitive C reaction protein + 0.479 * lymphocyte number. According to the acute exacerbation malnutrition risk prediction model for the patient with the chronic obstructive pulmonary disease of the aged and the construction method thereof, the prediction model for rapidly and accurately screening and evaluating the acute exacerbation malnutrition risk of the patient with the chronic obstructive pulmonary disease of the aged is established.

The present invention provides a method and system for predicting malnutrition in hemodialysis patients based on AI technology. The system includes a data collection module, a data preprocessing module, a data standardization module, a dimensionality reduction module, and a nutritional status prediction module. The method includes the following steps: S1: Collect relevant attributes of hemodialysis patients to obtain a hemodialysis patient dataset; S2: Preprocess the hemodialysis patient dataset; S3: Standardize the hemodialysis patient dataset; S4: Feature selection and model construction methods; S5: Model training and generation. The method of the present invention can comprehensively analyze patients by using AI technology combined with multi-dimensional data, can more comprehensively predict the nutritional status of patients, and the evaluation results are comprehensive, avoiding the problems of predicting the nutritional status of hemodialysis patients based on only a few indicators in the prior art, the indicators being too single, and the prediction results being incomplete.

To provide a low nutritional state improving agent capable of improving a symptom caused by a low nutritional state, a composition containing the low nutritional state improving agent, a low nutritional state improving food product containing the low nutritional state improving agent, and a method for improving a low nutritional state using the low nutritional state improving agent.SOLUTION: There are provided: a low nutritional state improving agent which contains pyrroloquinoline quinone and / or its salt as an active ingredient, and improves one or more symptoms among symptoms of a low nutrition state; a composition and a low nutritional state improving food product which contain the low nutritional state improving agent; and a method for improving a low nutritional state using the low nutritional state improving agent.SELECTED DRAWING: Figure 3

The invention discloses a diet adjustment method and system for adjuvant treatment of thrombocytopenia, and the method comprises the steps: obtaining a diet tendency list of patients, determining a food recommendation index of each patient in the same class, and constructing a patient-recommendation index matrix; complementing the recommendation index of the food, the element value of which is 0, of the specific patient in the patient-recommendation index matrix, and obtaining the final recommendation index # imgabs0 # of each kind of food; based on the final recommendation index # imgabs1 # of each kind of food, the key nutrient content of the food and the energy demand # imgabs2 # of the patient on that day, an optimal diet adjustment scheme is obtained. According to the method, BMI classification, diet tendency, daily energy demand and key nutrient control of patients are comprehensively considered, a personalized diet scheme is customized for each patient, food recommendation is optimized through a matrix decomposition technology, balanced intake of nutrients is ensured, and the problem of malnutrition or excess is effectively avoided.

The utility model relates to the technical field of livestock breeding, and discloses a quantitative feeding device which comprises a support, the upper portion of the support is fixedly connected with a material storage box, the upper portion of the material storage box is fixedly connected with a feeding port, a sealing assembly is arranged outside the material storage box and used for sealing the feeding port, and the sealing assembly is fixedly connected with the feeding port. A feeding trough is fixedly connected to the middle of the support, a weight sensor is installed on the lower portion of the feeding trough, a first motor is arranged on the rear side of the exterior of the support, the output end of the first motor is fixedly connected with a driving wheel, a rotating rod is rotationally connected to the interior of the storage box, and a quantitative roller is fixedly connected to the exterior of the rotating rod. According to the quantitative feeding device, the operation of quantitative feeding can be completed in the breeding process of the animal husbandry, it is ensured that each animal obtains appropriate nutrition, healthy growth of the animal is promoted, the problem of obesity caused by excessive feeding or malnutrition caused by insufficient feeding is solved, and the overall breeding benefit is improved.

The invention discloses an egg white protein source peptide capable of improving malnutrition and enhancing immunity and application of the egg white protein source peptide, and belongs to the technical field of small molecule peptides. Alkaline protease, papain and neutral protease are sequentially used for carrying out enzymolysis on egg white protein to prepare egg white protein peptide, wherein the egg white protein peptide contains tripeptide LPR with an immunity enhancing effect. Animal model function verification shows that the egg white protein peptide containing the tripeptide LPR can remarkably improve the levels of total protein, albumin, prealbumin and globulin in serum and the content of short-chain fatty acid in intestinal tracts, and the effect of improving malnutrition is achieved. The food-borne bioactive peptide is high in biological safety. Therefore, the tripeptide LPR or the egg white protein peptide containing the peptide fragment can be applied to preparation of medicines or health-care foods for improving malnutrition and enhancing immunity. The invention provides a theoretical support basis for the efficacy of the egg white protein peptide in the aspect of improving malnutrition.

The utility model discloses a dog food putting device, which relates to the technical field of automation control, and comprises a bottom plate, the outer wall of the top of the bottom plate is fixedly connected with a fixing frame, a plurality of grooves are arranged in the fixing frame, the inner wall of the bottom of the bottom plate is fixedly connected with a plurality of putting pipelines, and the putting pipelines are communicated with the grooves. According to the dog food feeding device, through the discharging pipe, when the discharging pipe and the storage tank are completely separated, the baffle on the discharging pipe can gradually seal the storage tank, dog food in the storage tank is prevented from being scattered, then the cover plate and the discharging pipe are in a separated state, and the dog food can be fed into the discharging pipe. According to the automatic feeding device for the dog food, the dog food which falls into the discharging pipe from the storage tank falls into the feeding pipeline from the groove and then falls into the discharging box, so that the effect of automatically feeding the dog food is achieved, the situation that too much or too little feeding possibly occurs due to manual feeding is avoided, the healthy body weight of the dog can be maintained, and the problems of obesity or malnutrition and the like can be prevented.

The invention relates to the technical field of intestinal obstruction catheters, and particularly discloses a novel intestinal obstruction catheter placed through abdominal wall-stomach fistulization, the novel intestinal obstruction catheter comprises a cannula, an abdomen and a stomach, one end of the cannula penetrates through the abdomen and the stomach under the guidance of a gastroscope, a first fixing mechanism is arranged at one end of the cannula, and a first through hole and a second through hole are formed in the cannula; a catheter body and a nutrient canal are installed in the first through hole and the second through hole respectively, a fixing end is installed at the other end of the cannula, a connecting opening is formed in one end of the catheter body, and a sheath tube is inserted in the connecting opening. According to the intestinal obstruction catheter, the cannula is directly installed in the stomach of a patient, and then the catheter body penetrates through the cannula and is placed in the intestinal tract of the patient, so that the situation that the catheter body directly penetrates through the nostril-esophagus of the patient to cause great pain to the patient, especially the patient needing to place the intestinal obstruction catheter for a long time, is avoided; and the catheter body is matched with the nutrition tube, so that nutrition can be conveniently supplied to the intestines, and the malnutrition condition of the patient is avoided.

The invention discloses a traditional Chinese medicine ointment for treating eczema. Traditional Chinese medicine believes that eczema is related to invasion of wind, dampness and heat evil and is often caused by improper diet, emotional disorder, external environment and the like, the key of pathogenesis is that dampness evil disturbs the spleen to cause unsmooth qi and blood, skin dystrophy and skin macular itching, and eczema is related to internal organ disorder. Aiming at the pathogenesis of eczema, rhizoma smilacis glabrae, orpiment, radix cynanchi paniculati, cortex dictamni and radix scutellariae are selected and blended into paste with medical glycerin, the paste is smeared on an affected part to achieve the purposes of clearing heat, eliminating dampness, nourishing blood, dispelling wind, relieving itching, inducing diuresis, diminishing swelling and dispelling wind and eliminating dampness so as to treat both symptoms and root causes, and clinical verification shows that the ointment is remarkable in curative effect, convenient to use and worthy of popularization and application.

The utility model discloses a rice variety salt tolerance cultivation device, and belongs to the technical field of rice cultivation. A rice variety salt tolerance cultivation device comprises a cultivation box and a spray head, a cultivation tray is arranged in the cultivation box, the rice variety salt tolerance cultivation device further comprises a sliding rail with a sliding block, the sliding rail is transversely arranged above the cultivation tray, and a driving part for driving the sliding block to slide is arranged between the sliding block and the sliding rail; the rotating seat is rotationally installed below the sliding block through a transmission shaft, a conveying pipe is fixedly connected to the rotating seat, the spray head is fixedly connected to the lower portion of the conveying pipe, and a connecting part is arranged on the sliding block; the driving part drives the sliding block to slide along the sliding rail so as to drive the spray head to synchronously move for movable irrigation, meanwhile, the connecting part drives the rotating seat and the conveying pipe to rotate so as to drive the spray head to continuously change the spraying angle, irrigation is more uniform, and the situation that the salt tolerance of rice is affected due to malnutrition is prevented.

The invention relates to the technical field of virus targeted therapy, in particular to application of a 2 / 5 type recombinant adeno-associated virus to intervention of expression of Bmal1, and application of the 2 / 5 type recombinant adeno-associated virus to intervention of expression of Bmal1, including targeting venation plexus and intervention of expression of Bmal1 through the 2 / 5 type recombinant adenovirus, and at least one of the following applications: (1) improving amyloid plaque deposition; (2) A beta pathology; and (3) the pathology of the malnutrition neuriposis. According to the invention, the 2 / 5 type recombinant adeno-associated virus is used for targeting venation plexus to intervene the expression of Bmal1 so as to improve amyloid plaque deposition, A beta pathology and nutritional neurite pathology; on the animal experiment level, it is proved that the AD pathology can be relieved by interfering the expression of the Bmal1 with the targeted venation plexus, so that a new thought is provided for AD treatment, and a foundation is laid for manufacturing the medicine for treating AD with the targeted venation plexus.

The present invention relates to the use of a probiotic composition comprising the probiotic strains Lactobacillus plantarum DSM 33363, Lactobacillus plantarum DSM 33364, Lactobacillus paracasei DSM 33373, Lactobacillus reuteri DSM 33374, Bacillus megatherium DSM 33300, Bacillus pumilus DSM 33297, Bacillus pumilus DSM 33355 ("Promotrient" consortia) for the treatment and prevention of malnutrition in humans and animals, such as human beings and animals, such as human beings and animals. It increases the nutritional value of cereal foods, in particular from wheat, by increasing the bioavailability of essential micronutrients and amino acids contained in these foods.

The invention discloses an old people chronic disease home monitoring system and method based on the Internet of Things, and relates to the technical field of old people chronic diseases, and the system obtains the diet data of the old people home through an Internet of Things device, and determines the cognitive problem of the old people based on the diet data of the old people home; acquiring living activity data of the old people, and determining a mode for intervening cognition of the old people based on the living activity data of the old people; intervening the cognitive problem of the old people according to the cognitive problem of the old people; interference is carried out through the Internet of Things equipment, the elderly can obtain the nutritional ingredients, health benefits and related information of influence on the illness state of the elderly, wrong cognition is broken through through the information, the elderly can be helped to intake enough nutrients such as protein, carbohydrate, fat, vitamins and mineral substances, and the possibility that the problem of insufficient nutrition occurs is reduced.