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452 results about "Magnesium stearate" patented technology

Magnesium stearate is the chemical compound with the formula Mg(C₁₈H₃₅O₂)₂. It is a soap, consisting of salt containing two equivalents of stearate (the anion of stearic acid) and one magnesium cation (Mg²⁺). Magnesium stearate is a white, water-insoluble powder. Its applications exploit its softness, insolubility in many solvents, and low toxicity. It is used as a release agent and as a component or lubricant in the production of pharmaceuticals and cosmetics.

Dotenorad tablet capable of being efficiently dissolved out and preparation method of dotenorad tablet

The invention discloses an efficient-dissolution dotenorad tablet and a preparation method thereof, and relates to the technical field of tablet preparation. The tablet consists of 5-20 parts of a dotenorad active component, 10-30 parts of a disintegrating agent, 40-70 parts of a filling agent, 0.5-5 parts of a surfactant, 0.5-3 parts of a lubricant, 1-5 parts of an adhesive and 0.5-1 part of an antioxidant. The preparation method comprises the following steps: premixing active components and auxiliary materials, carrying out high-shear wet granulation to form porous structure particles, carrying out precise temperature-control drying through a fluidized bed, carrying out micronization treatment to regulate the specific surface area of the particles, and finally, carrying out high-pressure tablet forming through a magnesium stearate / aerosil compound lubrication system. The dissolution rate of the tablet in a medium with the pH value of 6.8 for 15 minutes reaches 85% or above, meanwhile, long-term stability is achieved by inhibiting oxidative degradation, and the tablet has the dual advantages of quick effect taking and stable storage.
Owner:CHANGZHOU YINSHENG PHARMA

A pulverization process of a derivative biomass hard carbon material

The application discloses a kind of derived biomass hard carbon material pulverization process, belong to biomass charcoal material processing technical field, first, pulverization process includes the following steps: after drying, the coconut shell derived hard carbon block is carried out primary crushing, while spraying first modifier, obtain the particle size 1~3mm of coarse crushing modified particle;Coarse crushing modified particle is carried out secondary precision crushing under argon atmosphere, while spraying second modifier, obtain the precision crushing modified particle of D 50 Particle size is 15 μm;Precision crushing modified particle is carried out roll grinding spheroidization, while spraying third modifier, obtain the spherical modified particle of D 50 Particle size is 10 μm;Spherical modified particle is carried out flash drying after cooling, then add magnesium stearate to it, after mixing, obtain derived biomass hard carbon material.Then, the application realizes breakthrough in tap density, particle size distribution, first efficiency and other core indexes by the coordination of three-stage gradient modification and progressive pulverization process.
Owner:HUAXIAN DACHAOLIN BUSSAN

Composition containing antioxidant enzyme and preparation method thereof

The invention provides an antioxidant enzyme-containing composition and a preparation method thereof, and relates to the technical field of enteritis treatment. The preparation method comprises the following steps: S1, collecting various component materials for preparing the antioxidant enzyme-containing composition: collecting various raw materials for preparing glucan, fructo-oligosaccharide, galactooligosaccharide, superoxide dismutase, vitamin C, bunge cherry seed powder, cassia seed powder, turmeric, sorbitol, hydroxypropyl methyl cellulose, silicon dioxide and magnesium stearate; according to the invention, a matched powder bagging machine is adopted to realize full-automatic unattended operation to automatically complete the large bag filling and sealing step in the steps S4-S10, vacuumizing is performed firstly and then sealing is performed, and the storage space is compressed by vacuumizing, so that the condition that the bag is expanded and broken by internal air pressure in the transfer and storage process is not easy to cause; in the bag sealing process, the phenomena of high hot melting efficiency and high sealing speed are achieved by adopting a bag strip guiding and rolling hot melting mode.
Owner:LISHEN PHARM CO LTD

Polygonatum sibiricum and saussurea involucrate bone marrow peptide tablet as well

The invention relates to the technical field of functional product preparation, and provides a rhizoma polygonati and saussurea involucrata bone marrow peptide tablet as well as a preparation method and application thereof. The rhizoma polygonati and saussurea involucrata bone marrow peptide tablet is prepared from the following components: collagen peptide powder, L-isoleucine, a compound nutrient supplement, rhizoma polygonati, sorbitol, yak bone marrow peptide powder, fructus phyllanthi, fructus alpiniae oxyphyllae, mulberry powder, a saussurea involucrata culture and magnesium stearate. All the components of the rhizoma polygonati and saussurea involucrata bone marrow peptide tablet disclosed by the invention have a synergistic effect, so that the effects of conditioning sub-health, maintaining joints and assisting in treating diseases can be achieved.
Owner:SHIJIAZHUANG ZANGNUO BIOTECH

Preparation method of perindopril amlodipine tablet

The invention discloses a preparation method of perindopril amlodipine tablets, and belongs to the field of pharmacy. The perindopril amlodipine tablet is prepared from the following raw material medicines: arginine perindopril and amlodipine besylate and auxiliary materials: lactose, microcrystalline cellulose, hydrophobic colloidal silicon dioxide and magnesium stearate. The preparation method of the perindopril amlodipine tablet comprises the following steps: weighing according to the prescription amount, crushing and sieving the raw materials for pretreatment, sieving the whole particles of the auxiliary materials for pretreatment, premixing, feeding and total mixing, tabletting and the like. The prepared perindopril amlodipine tablet is relatively good in quality, high in stability and relatively few in waste products.
Owner:HAINAN HUALON PHARM

Preparation method and application of hydroxypropyl carboxymethyl composite starch ether with low bath ratio and high viscosity

The invention provides a preparation method and application of low-bath-ratio and high-viscosity hydroxypropyl carboxymethyl composite starch ether, and relates to the technical field of starch deep processing. The method comprises the following steps: S1, premixing corn starch with a compound base catalyst and magnesium stearate, and spraying an ethanol water solution for alkalization; s2, adding epoxypropane to carry out first-stage etherification, and then adding sodium chloroacetate to carry out second-stage etherification; and S3, after the reaction is finished, performing vacuum drying, crushing and sieving to obtain the high-viscosity hydroxypropyl carboxymethyl composite starch ether. Wherein the composite alkali catalyst comprises sodium hydroxide, sodium carbonate and calcium oxide. The starch ether obtained by the method has the advantages of high substitution degree, high viscosity, low solvent consumption and low energy consumption, and overcomes the defects of the traditional semi-dry method.
Owner:SHANDONG GUANGDA SAILU NEW MATERIALS TECHNOLOGY CO LTD

Solid dispersion-based sustained-release drug composite carrier as well as preparation method and application thereof

The invention relates to the technical field of pharmaceutical preparations, in particular to a solid dispersion-based sustained-release drug composite carrier as well as a preparation method and application thereof. The preparation method comprises the following steps: carrying out synergistic spray drying on double polymers (hydroxypropyl methylcellulose acetate succinate and polyvinylpyrrolidone-vinyl acetate copolymer) to form a solid dispersion; compounding with mesoporous silica and calcium silicate for localization, and spraying ethanol to activate pores; calcium stearate and magnesium stearate are sequentially added for lubrication; prefabricating a sustained-release skeleton master batch; and finally, mixing, rolling and forming. According to the method, through hierarchical structural design, the drug stability, the powder fluidity and the release controllability are remarkably improved, the method is suitable for industrial production of the dihydroergoline mesylate sustained release preparation, and a release curve is smooth and reliable.
Owner:宝利化(南京)制药有限公司

Composition for dispelling effects of alcohol and protecting liver and preparation method thereof

InactiveCN120550074AOrganic active ingredientsPeptide/protein ingredientsBiotechnologyCornus officinalis fruit extract
The invention discloses a hangover alleviating and liver protecting composition, which is prepared from the following components in parts by mass: 5 to 20 parts of radix puerariae extract, 5 to 20 parts of semen hoveniae extract, 5 to 20 parts of silybum marianum extract, 1 to 20 parts of rhizoma curcumae longae extract, 1 to 20 parts of rhizoma gastrodiae extract, 1 to 10 parts of lucid ganoderma extract, 1 to 20 parts of folium cortex eucommiae extract, 1 to 10 parts of fructus corni extract and 1 to 30 parts of corn oligopeptide powder. 1-50 parts of maltodextrin, 1-10 parts of microcrystalline cellulose, 1-2 parts of silicon dioxide and 1-2 parts of magnesium stearate. The total alcoholism-relieving and liver-protecting composition has the following beneficial effects: for acute drunkenness, the discomfort of drunkenness is obviously reduced, the chronic injury of alcohol to the liver is reduced, the systematic effect from alcohol metabolism to organ protection is realized through multi-target regulation and control, and the three-in-one effect of relieving alcoholism, protecting cells and regulating metabolism is achieved. The invention also discloses a preparation method of the alcohol effect dispelling and liver protecting composition.
Owner:ZHEJIANG BAIKEJIAN IND CO LTD

Plasmin lumbrukinase peptide dietary therapy formula suitable for rehabilitation of cardiovascular and cerebrovascular diseases, blood circulation promotion, stasis removal, thrombolysis, collateral dredging and microcirculation improvement

The invention discloses a plasmin lumbrukinase peptide dietary therapy formula suitable for rehabilitation of cardiovascular and cerebrovascular diseases, blood circulation promoting, blood stasis removing, thrombolysis, collateral dredging and microcirculation improving, and relates to the technical field of medicine and food homology dietary therapy. Soybean protein isolate and earthworm protein are used as core thrombolytic active raw materials, isomaltooligosacharide, xylitol, German Jilida collagen peptide, soybean peptide powder, Belgian imported inulin, red yeast rice and natto powder are compounded, microcrystalline cellulose and magnesium stearate are used as auxiliary materials, and probiotics / metabiotics strains such as rhamnolactobacilli JYLR-005 and the like can be selectively added. The raw materials have a synergistic effect through precise matching, plasmin and lumbrukinase peptide in earthworm protein can directly dissolve thrombus fibrin, natto powder and red yeast rice assist in lowering lipid and dissolving thrombus, multiple active peptides and prebiotics regulate intestinal microecology to improve microcirculation of the whole body, probiotics / metabiotics further strengthen the metabolic capacity of the body, no chemical medicine is added in the whole process, and the traditional Chinese medicine composition is free of toxic and side effects and free of toxic and side effects. The safety is high; the dietary therapy composition can achieve postoperative rehabilitation conditioning of cardiovascular and cerebrovascular diseases through daily consumption, effectively promote blood circulation to remove blood stasis, dissolve thrombus and dredge collaterals, improve microcirculation and relieve various discomfort caused by blood vessel clogging, raw materials are easy to obtain, compatibility is scientific, and the dietary therapy composition is suitable for large-scale production and popularization.
Owner:SHANDONG YUPIN TIANDAN MARINE BIOTECHNOLOGY CO LTD

High-color-fastness washable polyethylene fabric and preparation process thereof

The invention discloses a high-color-fastness washable polyethylene fabric and a preparation process thereof in the field of functional polymer materials. The high-color-fastness washable polyethylene fabric is prepared from the following raw materials: polyethylene resin, maleic anhydride-acrylic acid copolymer grafted polyethylene, dopamine-silane composite modified polyethylene, magnesium stearate and an antioxidant. Wherein the maleic anhydride-acrylic acid copolymer grafted polyethylene is prepared by copolymerizing maleic anhydride and acrylic acid and then blending and granulating with polyethylene, and carboxyl and acrylate groups are introduced to enhance the binding force with dye; the dopamine-silane composite modified polyethylene is prepared through polyethylene surface hydroxylation, dopamine self-polymerization modification and silane grafting reaction, and the acting force and hydrophobicity between fibers are doubly improved through a catechol group and an epoxy group. According to the prepared fabric, the color fastness and the washing resistance are remarkably improved, meanwhile, the original characteristics of light weight and chemical corrosion resistance of polyethylene are kept, and the application scene is expanded.
Owner:BIEM L FDLKK GARMENT CO LTD

Fiber-based food containers for emulsions

Systems and methods are described for fiber-based, plastic-free products for storage of emulsion food products. In some embodiments, a coating is applied to the product, such as a coating comprising efficacious proportions of xylitol, citric acid, water, microfibrillated cellulose, and polyvinyl alcohol. A slurry is used to fabricate the product includes various proportions of fiber blends (e.g., combinations of bleached softwood, bleached hardwood, kraft paper, and / or virgin fiber), AKD, starch, a stearate (e.g., Magnesium or Calcium Stearate), a defoamer, and microfibrillated cellulose.
Owner:FOOTPRINT INT LLC

Orange enhanced color masterbatch and its preparation method

ActiveCN119286000BPolymer sciencePhotopigment
The present invention discloses an orange enhanced masterbatch and a preparation method thereof, belonging to the technical field of polymer material coloring. The method includes mixing and ball-milling a pigment with a modified coupling agent, adding magnesium stearate and then sand-milling to obtain a color paste; mixing the color paste with PP, antioxidant, plasticizer and light stabilizer and carrying out intensive mixing; then extruding and pelletizing through a twin-screw extruder to obtain a pretreated masterbatch; finally drying and screening to obtain the orange enhanced masterbatch. Compared with the prior art, the present invention is prepared by a specific synthesis process, enhancing the compatibility between the pigment and PP, and improving the dispersibility and aging resistance of the masterbatch. The masterbatch of the present invention has excellent color uniformity, stability and aging resistance, and is applicable to the field of high-performance plastic coloring.
Owner:SHENZHEN JINZHICHENG PLASTIC TECH CO LTD

Nintedanib dry powder inhalant as well as preparation method and application thereof

The invention relates to a nintedanib dry powder inhalant as well as a preparation method and application thereof. The dry powder inhalant comprises nintedanib and magnesium stearate. According to the nintedanib dry powder inhalant, by controlling the adding proportion of magnesium stearate and the particle size distribution of co-micro powder, the dosage of fine particles can be remarkably increased, the nintedanib dry powder inhalant still has the high dosage of fine particles under the high drug loading capacity, the drug bioavailability is high, and the safety risk of a patient in the medication period can be reduced. Meanwhile, the preparation method of the nintedanib dry powder inhalant is simple and controllable, and the final product is safe, reliable and high in stability.
Owner:ATMEN (SUZHOU) PHARMACEUTICAL TECHNOLOGY CO LTD

Preparation process of aluminum hydroxide modified barium sulfate powder

The invention relates to the technical field of preparation of barium sulfate powder, and discloses a preparation process of aluminum hydroxide modified barium sulfate powder, which comprises the following steps: constructing high-density sulfate radical active sites through argon plasma activation, and combining with a bio-based coupling agent to realize triple chemical bonding of barium sulfate and aluminum hydroxide; dynamically controlling hydrolysis of the aluminum salt by adopting microwave pulse in cooperation with a spiral microreactor to generate a nanoscale aluminum hydroxide uniform coating layer; supercritical CO2 is introduced to synchronously regulate and control the pH and the anti-solvent effect, side reaction is inhibited, and coating compactness is optimized; a closed-loop aluminum salt recovery system is combined to realize resource cyclic utilization; finally, the application performance of the powder is improved through hydrophobic treatment of magnesium stearate. Compared with a traditional acid pickling activation and continuous heating process, the chemical pollution risk is avoided, the bonding strength of a coating layer is improved by 60% or above, the utilization rate of aluminum salt reaches 98%, and the powder hydrophobicity and the plastic processing adaptability are remarkably optimized.
Owner:HENAN SILICON JIUHUA INNOVATION TECHNOLOGY CO LTD

Sports nutrition solid-state food for supplementing protein and preparation method of sports nutrition solid-state food

The invention discloses a sports nutrition solid food for supplementing protein and a preparation method, and belongs to the technical field of foods.The sports nutrition solid food is prepared from, by weight, 31-60 parts of compound amino acid powder, 10-15 parts of isomaltitol, 1-6 parts of taurine, 1-5 parts of Chinese yam peptide, 5 parts of glycine, 5 parts of gamma-aminobutyric acid, 5 parts of L-lysine hydrochloride and 1 part of yeast protein powder. The formula comprises the following components in parts by weight: 1-3 parts of whey protein powder, 1-2 parts of hydroxymethyl propyl cellulose, 0.1-1 part of yeast extract, 0.1-1 part of yeast beta-glucan, 2-6 parts of bovine colostrum powder, 0.5 part of stevioside, 0.1 part of zinc glycinate, 0.1 part of ferrous lactate, 0.5 part of essence and 2-3 parts of magnesium stearate. The compound amino acid powder, the Chinese yam peptide, the glycine, the L-lysine hydrochloride, the yeast protein powder, the whey protein powder, the yeast extract and the bovine colostrum powder are compounded, so that protein consumed by a human body after exercise can be comprehensively supplemented.
Owner:上海圣岳生物科技有限公司

Anti-aging capsule compounded by PQQ and mitochondrial nutrients

The invention relates to an anti-aging capsule compounded by PQQ and mitochondrial nutrients, and discloses an anti-aging capsule which is prepared by synergistically compounding a plurality of mitochondrial nutrients according to a scientific proportion and supplementing high-purity raw materials and slow-release dosage forms to realize energy metabolism activation and anti-oxidation synergistic intervention. Therefore, the anti-aging capsule systematically delays aging through multi-target regulation and control of mitochondrial functions. The capsule is characterized by comprising the following components in parts by weight: 1-20 mg of pyrroloquinoline quinone disodium salt (PQQ), 20-100 mg of coenzyme Q10, 50-200 mg of L-carnitine tartrate, 10-100 mg of alpha-lipoic acid, 50-300 mg of nicotinamide mononucleotide (NMN) or nicotinamide nucleoside (NR), and 10-50 [mu] g of selenoprotein or organic selenium yeast, and a capsule carrier comprises 100 mg of gelatin or a plant-derived capsule shell, 180 mg of microcrystalline cellulose, 5 mg of magnesium stearate and 5 mg of silicon dioxide.
Owner:JIANGSU SHAREJOY HEALTH TECH CO LTD

Astragaloside synergistic composition as well as preparation method and application thereof

The invention discloses an astragaloside synergistic type composition as well as a preparation method and application of the astragaloside synergistic type composition. Comprising the following components: 8 to 16 parts of astragaloside, 20 to 40 parts of a honeysuckle flower extract, 10 to 20 parts of L-carnitine, 0.1 to 0.5 part of selenium yeast, 3 to 8 parts of diammonium glycyrrhizinate, 5 to 15 parts of taurine, 8 to 20 parts of a fructus forsythiae extract, 2 to 7 parts of vitamin E, 12 to 32 parts of hydroxypropyl-beta-cyclodextrin, 2 to 10.5 parts of maltodextrin, 1 to 7 parts of Arabic gum, 10 to 20 parts of lactose, 1 to 3 parts of zinc gluconate and 2 to 5 parts of magnesium stearate. 1-3 parts of vitamin C, 1-5 parts of xanthan gum and 1-3 parts of lecithin. The composition has a wide application prospect in preparation of veterinary drugs or veterinary food additives.
Owner:JIANGXI CHENGBIXIN BIOTECHNOLOGY CO LTD

Sustained-release pellet particles containing gamma-aminobutyric acid and preparation method of sustained-release pellet particles

PendingCN121714541AOrganic active ingredientsNervous disorderSustained release pelletsAlcohol sugars
The invention provides a sustained-release pellet containing gamma-aminobutyric acid, the sustained-release pellet comprises a pellet core and a coating layer wrapping the pellet core, the pellet core contains a physiologically active substance, and the physiologically active substance is gamma-aminobutyric acid; the pellet core comprises the following components in parts by weight: 15-40 parts of gamma-aminobutyric acid, 30-55 parts of a filling agent, 1-30 parts of a lubricating agent and 0.5-5 parts of an anti-caking agent; the filling agent comprises at least one of microcrystalline cellulose, powdery cellulose, starch and derivatives thereof, hydroxypropyl cellulose, hydroxypropyl methylcellulose, low-substituted hydroxypropyl cellulose, sugar or sugar alcohol and fruit and vegetable powder; the lubricant comprises at least one of talcum powder, magnesium stearate, stearic acid, glycerol and leucine; the anti-caking agent comprises at least one of magnesium carbonate, tricalcium phosphate, calcium hydrophosphate and silicon dioxide.
Owner:XIAN LE JIAN KANG KE JI (GUANG DONG) YOU XIAN GONG SI

Milanserin hydrochloride tablet

PendingCN120678739ANervous disorderPharmaceutical non-active ingredientsCelluloseMianserin Hydrochloride
The invention discloses a mianserin hydrochloride tablet prepared in a wet granulation mode. The mianserin hydrochloride tablet is prepared from mianserin hydrochloride anhydride, calcium hydrogen phosphate, corn starch, hydroxypropyl methylcellulose, colloidal silicon dioxide, magnesium stearate and a film coating agent. According to the mianserin hydrochloride tablet and the preparation method thereof, the stability of the mianserin hydrochloride tablet is improved by using the high-concentration adhesive solution and optimizing the granulation parameter range, the problem that related substances are increased due to crystal transformation of active ingredients in the product preparation process is solved, and the medication safety of patients is better guaranteed.
Owner:YANGTAI PHARMA SHANDONG

Preparation method of Kyoho grape young fruit polyphenol buccal tablet and product of Kyoho grape young fruit polyphenol buccal tablet

The invention discloses a preparation method of Kyoho grape young fruit polyphenol buccal tablets and a product thereof. The method comprises the following steps: (1) preparing grape young fruit powder: adding 0.1-0.3% of a Vc protective agent and 15-20% of a maltodextrin drying aid into Kyoho grape young fruits, homogenizing, filtering, adjusting the solid concentration to 15-25%, performing spray drying, and collecting the young fruit powder; and (2) tabletting buccal tablets: taking 1.5-3.0 parts by weight of young fruit powder, 4-6 parts by weight of corn starch, 3-5 parts by weight of glucose, 0.1-0.3 part by weight of Vc and 0.08-0.12 part by weight of magnesium stearate, mixing, tabletting and forming. According to the method, the problem of resource waste caused by the fact that young fruits of Kyoho grapes in the fruit thinning period cannot be eaten due to high acerbity is solved, meanwhile, the problem that the young fruits adhere to the wall is solved through optimization of a spray drying process, efficient utilization of polyphenol active ingredients and high-value utilization of the young fruits of the grapes are achieved, and planting economic benefits are improved.
Owner:INST OF AGRI ENG TECH FUJIAN ACAD OF AGRI SCI +1

Heart and cerebral vessel health care composition with thrombolytic and antithrombotic functions and preparation method thereof

The invention relates to the technical field of food processing, and particularly discloses a heart and cerebral vessel health care composition with thrombolytic and antithrombotic functions and a preparation method thereof. The composition consists of the following raw materials: sorbitol, red yeast rice, freeze-dried natto powder, earthworm protein peptide, vitamin C, American ginseng peptide, magnesium stearate, an angelica sinensis extract, rice bran fatty alkanol, vitamin B1, vitamin B2, a turmeric extract and a compound coloring agent. The preparation method comprises the following steps: mixing the raw materials except magnesium stearate in a double-cone mixer; magnesium stearate is added for continuous mixing, and a hollow capsule shell is filled with the mixed material. The composition disclosed by the invention forms a multi-dimensional synergistic system for smoothing blood vessels, purifying blood and improving blood flow, the defect of single effect of an existing product is overcome, the health-care effect of heart and cerebral vessels is remarkably improved, and the effect is stable and controllable; in addition, the preparation method has the advantages of being simple and controllable in process and suitable for industrial production.
Owner:JIUJIANG KUNHAO TRADING CO LTD

Preparation method of ceramic filler powder and porous ceramic

The invention discloses ceramic filler powder and a preparation method of porous ceramic, and relates to the technical field of ceramic. According to the invention, the raw material components are reasonably proportioned, and the superfine SiC-coated MgAl-LDH compound is used as an additive to be mixed with kaolin, potassium feldspar, quartz, aluminum oxide, silicon carbide and talc to prepare the ceramic filler powder. On the basis, the prepared ceramic filler powder is mixed with carboxymethyl cellulose, polyvinyl alcohol, water glass, magnesium stearate and water, then the mixture is subjected to filter pressing, vacuum pugging and aging, and then the porous ceramic is prepared through a forming process and a sintering process. The porous ceramic prepared from the ceramic filler powder provided by the invention has better compressive strength and corrosion resistance, is beneficial to expanding the application field of products, and particularly meets the requirements of high-end industries.
Owner:PINGXIANG HENGXI CHEM PACKING CO LTD

A bucumlan tablet and a method for preparing the same

The application discloses a kind of bumetanide tablets, raw materials include bumetanide 1 according to mass ratio;Corn starch 81~85;Lactose 50~54;Agar 0.1~0.3;Povidone K304~6;Polysorbate 80, 0.1~0.2;Silicon dioxide 3~4.5;Talcum powder 2~3.3;Magnesium stearate 0.3~0.7.Its preparation method includes the following steps: pretreatment, premixing, granulation, wet granulation, drying, dry granulation, total mixing, tabletting and packaging.The application introduces the synergistic system of trace agar and polysorbate 80 in the prescription.Agar, as a natural hydrophilic colloid, can form a hydrophilic network structure during the granulation process, and synergistically act with polysorbate 80, greatly improving the wettability and dispersibility of the slurry to ultrafine bumetanide, preventing drug agglomeration, so that the drug can be more evenly distributed in the granules during the subsequent drying and tabletting process.
Owner:JIANGSU SHENLONG PHARMA

Compound soft chewable tablet as well as preparation method and application thereof

The invention relates to the technical field of animal medicines, and particularly discloses a compound soft chewable tablet as well as a preparation method and application thereof. The compound soft chewable tablet comprises the following raw materials in percentage by weight: 0.4% of tofacitinib, 1% of an echinacea extract, 10-20% of pork liver powder, 10-20% of polyethylene glycol, 3-15% of a release agent, 0.3-1% of lauryl sodium sulfate, 1-3% of magnesium stearate, 2-5% of sucrose, 0.05-0.5% of a preservative, 11% of glycerol, 13-15% of soybean oil and the balance of corn starch. The tofacitinib citrate and the echinacea extract are adopted to prepare the soft chewable tablet, the process has no special requirements on equipment, the process is simple and feasible, and industrial production is utilized; by adopting conventional equipment such as a wet granulator, a mixer and a forming machine, the prepared oral product has the characteristics of stability, palatability, safety and effectiveness.
Owner:QILU ANIMAL HEALTH PRODUCTS CO LTD

Propolis composition and preparation method and device thereof

The invention relates to the technical field of treatment of stomach diseases, and provides a propolis composition which is prepared from the following raw materials in parts by weight: 5-30 parts of propolis, 3-20 parts of radix angelicae sinensis, 3-20 parts of rhizoma chuanxiong, 5-25 parts of paederia scandens and 2-15 parts of rhizoma atractylodis macrocephalae. The auxiliary material comprises at least one of microcrystalline cellulose, hydroxypropyl methyl cellulose and magnesium stearate, and the additive comprises 0.1-2 parts of probiotic powder and 3-10 parts of fructo-oligosaccharide, wherein the auxiliary material accounts for 15-35% of the total weight of the auxiliary material; and carrying materials: 2-12 parts of astragalus membranaceus and 1-8 parts of liquorice. Through the synergistic effect of propolis flavone, astragalus polysaccharide and probiotics, the serum IgG and IgA levels are increased by 30-40%, and the NK cell activity is increased by 45%; the abundance of intestinal lactobacillus / bifidobacterium is increased by 3-4 times, the content of short-chain fatty acid is increased by 50%, and the intestinal barrier function is remarkably enhanced; and the levels of inflammatory factors IL-6 and TNF-alpha are reduced by 30-40%, which is superior to that of a single propolis preparation.
Owner:JIANGSU RIGAO BEE PROD

A sustained-release bupropion hydrochloride preparation and a method for preparing the same

The application provides a bupropion hydrochloride sustained-release tablet and a preparation method, and belongs to the technical field of pharmacy. The pharmaceutical composition contains 150 parts of bupropion hydrochloride, 122.5-157.5 parts of glycerin monostearate, 17.5-22.5 parts of triethyl citrate, 68-104 parts of microcrystalline cellulose and 2-6 parts of magnesium stearate, wherein the bupropion hydrochloride raw material and the glycerin monostearate and the triethyl citrate are prepared into a solid dispersion through a hot melt extrusion process. The application provides a bupropion hydrochloride sustained-release tablet which is stable in drug release, slow in growth of related substances, does not need to be coated and can be taken and eaten, and a preparation method.
Owner:DISHA PHARMA GRP

Long-acting antistatic glass fiber reinforced polypropylene composite material as well as preparation method and application thereof

The invention provides a long-acting antistatic glass fiber reinforced polypropylene composite material as well as a preparation method and application thereof. The long-acting antistatic glass fiber reinforced polypropylene composite material is prepared from the following components in parts by weight: 70 to 90 parts of glass fiber reinforced polypropylene, 10 to 20 parts of antistatic master batch, 0.1 to 0.5 part of antioxidant and 0.5 to 1 part of magnesium stearate, wherein the antistatic master batch comprises the following components in parts by weight: 80-85 parts of a polypropylene base material, 15-20 parts of nano ATO, 2-3 parts of a polyethylene wax dispersing agent and 0.5-1 part of a lubricating agent. According to the invention, the nano ATO is pre-dispersed in the antistatic master batch and then is subjected to synergistic copolymerization with a glass fiber network in the glass fiber reinforced polypropylene, and the surface resistivity of the composite material can be reduced to 106-108 omega.cm through a small addition amount. Compared with carbon black and other traditional fillers in the prior art, the addition amount of the nano ATO in the application is small, so that the surface resistivity of the composite material can be reduced to 10 < 6 >-10 < 8 > omega.cm, and the surface resistivity of the composite material can be reduced to 10 < 6 >-10 < 8 > omega.cm. The density, the color and the mechanical property of the composite material are not influenced.
Owner:ZHUHAI GREE NEW MATERIAL CO LTD

Modified PVB (Polyvinyl Butyral) material based on nano silicon dioxide and preparation method of modified PVB material

PendingCN121758885AEpoxyPolymer science
The invention relates to the technical field of polyvinyl butyral modified materials, and discloses a modified PVB (polyvinyl butyral) material based on nano-silica and a preparation method thereof, the modified PVB material is prepared from the following raw materials by weight: 100 parts of polyvinyl butyral resin; 25 to 45 parts of triethylene glycol di-2-ethylhexoate; 0.5 to 5.0 parts of nano silicon dioxide; 0.05 to 0.50 part of a titanate coupling agent; 0.02 to 0.15 part of magnesium stearate; and 1.0 to 5.0 parts of epoxidized soybean oil. The method comprises the following steps: dispersing silicon dioxide by a plasticizer, dehydrating, adding a coupling agent for in-situ grafting, and compounding a stabilizer to prepare mother liquor; infiltrating the mother liquor into the resin to obtain a swelling material; and performing temperature-controlled extrusion. The modified PVB material based on nano silicon dioxide prepared by the invention solves the problems of particle agglomeration and yellowing, and has high transparency, high strength and excellent heat aging resistance.
Owner:CHENGDU LONGCHENG HIGH TECH MATERIAL

Anti-drunkenness composition and application thereof

PendingCN121313676ANervous disorderHydroxy compound active ingredientsSerum glutamate pyruvate transaminaseAlanine aminotransferase
The invention discloses an anti-drunkenness composition and application thereof. The invention provides an application of a composition in preparation of an anti-drunkenness product, the composition contains edible plasma powder, xylitol, fructo-oligosaccharide, microcrystalline cellulose, mogroside and magnesium stearate, and the edible plasma powder contains immune globulin IgG. The TZK provided by the invention has obvious regulation and improvement effects on sleep behaviors, serum indexes and gastrointestinal injury after acute drinking. The oxidative stress state after long-term large-dose chronic drinking is effectively adjusted, so that the oxidative stress injury index malondialdehyde (MDA) gradually returns to the normal level; according to the present invention, the activity of the liver injury markers such as alanine transaminase (ALT) and aspartate transaminase (AST) is reduced, the liver protection effect is provided, and the gastric mucosa structure repair is promoted by increasing the gastric mucosa prostaglandin content and reducing the local MDA level;
Owner:XIANGYANG WEIEN BIOTECHNOLOGY CO LTD

Ginseng, cape jasmine and sunflower disc composition, ginseng, cape jasmine and sunflower disc slices, and preparation method and application of ginseng, cape jasmine and sunflower disc composition

The invention discloses a ginseng, cape jasmine and sunflower disc composition, a ginseng, cape jasmine and sunflower disc slice and a preparation method and application of the ginseng, cape jasmine and sunflower disc composition, and belongs to the technical field of functional food. In order to solve the problems of large side effects, complex components and the like of the existing gout treatment medicines, the invention optimizes the preparation methods of a sunflower disc extract, a gardenia extract, a ginseng extract, a corn stigma extract, a dandelion extract and a cichorium intybus extract through the methods of extraction, enzymolysis, molecular weight interception and the like. The obtained extract is rich in active sugar compounds with small molecular weights, flavones, alkaloids and other effective components. The invention also provides a health-care product prepared from 80-120 parts by weight of sunflower disc extract, 5-15 parts by weight of gardenia extract, 15-30 parts by weight of ginseng extract, 6-10 parts by weight of corn stigma extract, 6-10 parts by weight of dandelion extract and 5-15 parts by weight of cichorium intybus extract. The invention discloses a composition composed of 80-100 parts by weight of microcrystalline cellulose, 1-2 parts by weight of magnesium stearate and 1-2 parts by weight of sorbitol, and a preparation method thereof. The composition can be used for development of health care products and medicines for improving gout and / or hyperuricemia.
Owner:JILINSHENG JINZIYUAN BIOTECHNOLOGY LTD