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176 results about "Magnesium stearate" patented technology

Magnesium stearate is the chemical compound with the formula Mg(C₁₈H₃₅O₂)₂. It is a soap, consisting of salt containing two equivalents of stearate (the anion of stearic acid) and one magnesium cation (Mg²⁺). Magnesium stearate is a white, water-insoluble powder. Its applications exploit its softness, insolubility in many solvents, and low toxicity. It is used as a release agent and as a component or lubricant in the production of pharmaceuticals and cosmetics.

A pulverization process of a derivative biomass hard carbon material

The application discloses a kind of derived biomass hard carbon material pulverization process, belong to biomass charcoal material processing technical field, first, pulverization process includes the following steps: after drying, the coconut shell derived hard carbon block is carried out primary crushing, while spraying first modifier, obtain the particle size 1~3mm of coarse crushing modified particle;Coarse crushing modified particle is carried out secondary precision crushing under argon atmosphere, while spraying second modifier, obtain the precision crushing modified particle of D 50 Particle size is 15 μm;Precision crushing modified particle is carried out roll grinding spheroidization, while spraying third modifier, obtain the spherical modified particle of D 50 Particle size is 10 μm;Spherical modified particle is carried out flash drying after cooling, then add magnesium stearate to it, after mixing, obtain derived biomass hard carbon material.Then, the application realizes breakthrough in tap density, particle size distribution, first efficiency and other core indexes by the coordination of three-stage gradient modification and progressive pulverization process.
Owner:HUAXIAN DACHAOLIN BUSSAN

Solid dispersion-based sustained-release drug composite carrier as well as preparation method and application thereof

The invention relates to the technical field of pharmaceutical preparations, in particular to a solid dispersion-based sustained-release drug composite carrier as well as a preparation method and application thereof. The preparation method comprises the following steps: carrying out synergistic spray drying on double polymers (hydroxypropyl methylcellulose acetate succinate and polyvinylpyrrolidone-vinyl acetate copolymer) to form a solid dispersion; compounding with mesoporous silica and calcium silicate for localization, and spraying ethanol to activate pores; calcium stearate and magnesium stearate are sequentially added for lubrication; prefabricating a sustained-release skeleton master batch; and finally, mixing, rolling and forming. According to the method, through hierarchical structural design, the drug stability, the powder fluidity and the release controllability are remarkably improved, the method is suitable for industrial production of the dihydroergoline mesylate sustained release preparation, and a release curve is smooth and reliable.
Owner:宝利化(南京)制药有限公司

Plasmin lumbrukinase peptide dietary therapy formula suitable for rehabilitation of cardiovascular and cerebrovascular diseases, blood circulation promotion, stasis removal, thrombolysis, collateral dredging and microcirculation improvement

The invention discloses a plasmin lumbrukinase peptide dietary therapy formula suitable for rehabilitation of cardiovascular and cerebrovascular diseases, blood circulation promoting, blood stasis removing, thrombolysis, collateral dredging and microcirculation improving, and relates to the technical field of medicine and food homology dietary therapy. Soybean protein isolate and earthworm protein are used as core thrombolytic active raw materials, isomaltooligosacharide, xylitol, German Jilida collagen peptide, soybean peptide powder, Belgian imported inulin, red yeast rice and natto powder are compounded, microcrystalline cellulose and magnesium stearate are used as auxiliary materials, and probiotics / metabiotics strains such as rhamnolactobacilli JYLR-005 and the like can be selectively added. The raw materials have a synergistic effect through precise matching, plasmin and lumbrukinase peptide in earthworm protein can directly dissolve thrombus fibrin, natto powder and red yeast rice assist in lowering lipid and dissolving thrombus, multiple active peptides and prebiotics regulate intestinal microecology to improve microcirculation of the whole body, probiotics / metabiotics further strengthen the metabolic capacity of the body, no chemical medicine is added in the whole process, and the traditional Chinese medicine composition is free of toxic and side effects and free of toxic and side effects. The safety is high; the dietary therapy composition can achieve postoperative rehabilitation conditioning of cardiovascular and cerebrovascular diseases through daily consumption, effectively promote blood circulation to remove blood stasis, dissolve thrombus and dredge collaterals, improve microcirculation and relieve various discomfort caused by blood vessel clogging, raw materials are easy to obtain, compatibility is scientific, and the dietary therapy composition is suitable for large-scale production and popularization.
Owner:SHANDONG YUPIN TIANDAN MARINE BIOTECHNOLOGY CO LTD

Astragaloside synergistic composition as well as preparation method and application thereof

The invention discloses an astragaloside synergistic type composition as well as a preparation method and application of the astragaloside synergistic type composition. Comprising the following components: 8 to 16 parts of astragaloside, 20 to 40 parts of a honeysuckle flower extract, 10 to 20 parts of L-carnitine, 0.1 to 0.5 part of selenium yeast, 3 to 8 parts of diammonium glycyrrhizinate, 5 to 15 parts of taurine, 8 to 20 parts of a fructus forsythiae extract, 2 to 7 parts of vitamin E, 12 to 32 parts of hydroxypropyl-beta-cyclodextrin, 2 to 10.5 parts of maltodextrin, 1 to 7 parts of Arabic gum, 10 to 20 parts of lactose, 1 to 3 parts of zinc gluconate and 2 to 5 parts of magnesium stearate. 1-3 parts of vitamin C, 1-5 parts of xanthan gum and 1-3 parts of lecithin. The composition has a wide application prospect in preparation of veterinary drugs or veterinary food additives.
Owner:JIANGXI CHENGBIXIN BIOTECHNOLOGY CO LTD

Sustained-release pellet particles containing gamma-aminobutyric acid and preparation method of sustained-release pellet particles

PendingCN121714541AOrganic active ingredientsNervous disorderSustained release pelletsAlcohol sugars
The invention provides a sustained-release pellet containing gamma-aminobutyric acid, the sustained-release pellet comprises a pellet core and a coating layer wrapping the pellet core, the pellet core contains a physiologically active substance, and the physiologically active substance is gamma-aminobutyric acid; the pellet core comprises the following components in parts by weight: 15-40 parts of gamma-aminobutyric acid, 30-55 parts of a filling agent, 1-30 parts of a lubricating agent and 0.5-5 parts of an anti-caking agent; the filling agent comprises at least one of microcrystalline cellulose, powdery cellulose, starch and derivatives thereof, hydroxypropyl cellulose, hydroxypropyl methylcellulose, low-substituted hydroxypropyl cellulose, sugar or sugar alcohol and fruit and vegetable powder; the lubricant comprises at least one of talcum powder, magnesium stearate, stearic acid, glycerol and leucine; the anti-caking agent comprises at least one of magnesium carbonate, tricalcium phosphate, calcium hydrophosphate and silicon dioxide.
Owner:XIAN LE JIAN KANG KE JI (GUANG DONG) YOU XIAN GONG SI

Heart and cerebral vessel health care composition with thrombolytic and antithrombotic functions and preparation method thereof

The invention relates to the technical field of food processing, and particularly discloses a heart and cerebral vessel health care composition with thrombolytic and antithrombotic functions and a preparation method thereof. The composition consists of the following raw materials: sorbitol, red yeast rice, freeze-dried natto powder, earthworm protein peptide, vitamin C, American ginseng peptide, magnesium stearate, an angelica sinensis extract, rice bran fatty alkanol, vitamin B1, vitamin B2, a turmeric extract and a compound coloring agent. The preparation method comprises the following steps: mixing the raw materials except magnesium stearate in a double-cone mixer; magnesium stearate is added for continuous mixing, and a hollow capsule shell is filled with the mixed material. The composition disclosed by the invention forms a multi-dimensional synergistic system for smoothing blood vessels, purifying blood and improving blood flow, the defect of single effect of an existing product is overcome, the health-care effect of heart and cerebral vessels is remarkably improved, and the effect is stable and controllable; in addition, the preparation method has the advantages of being simple and controllable in process and suitable for industrial production.
Owner:JIUJIANG KUNHAO TRADING CO LTD

A bucumlan tablet and a method for preparing the same

The application discloses a kind of bumetanide tablets, raw materials include bumetanide 1 according to mass ratio;Corn starch 81~85;Lactose 50~54;Agar 0.1~0.3;Povidone K304~6;Polysorbate 80, 0.1~0.2;Silicon dioxide 3~4.5;Talcum powder 2~3.3;Magnesium stearate 0.3~0.7.Its preparation method includes the following steps: pretreatment, premixing, granulation, wet granulation, drying, dry granulation, total mixing, tabletting and packaging.The application introduces the synergistic system of trace agar and polysorbate 80 in the prescription.Agar, as a natural hydrophilic colloid, can form a hydrophilic network structure during the granulation process, and synergistically act with polysorbate 80, greatly improving the wettability and dispersibility of the slurry to ultrafine bumetanide, preventing drug agglomeration, so that the drug can be more evenly distributed in the granules during the subsequent drying and tabletting process.
Owner:JIANGSU SHENLONG PHARMA

A sustained-release bupropion hydrochloride preparation and a method for preparing the same

The application provides a bupropion hydrochloride sustained-release tablet and a preparation method, and belongs to the technical field of pharmacy. The pharmaceutical composition contains 150 parts of bupropion hydrochloride, 122.5-157.5 parts of glycerin monostearate, 17.5-22.5 parts of triethyl citrate, 68-104 parts of microcrystalline cellulose and 2-6 parts of magnesium stearate, wherein the bupropion hydrochloride raw material and the glycerin monostearate and the triethyl citrate are prepared into a solid dispersion through a hot melt extrusion process. The application provides a bupropion hydrochloride sustained-release tablet which is stable in drug release, slow in growth of related substances, does not need to be coated and can be taken and eaten, and a preparation method.
Owner:DISHA PHARMA GRP

Modified PVB (Polyvinyl Butyral) material based on nano silicon dioxide and preparation method of modified PVB material

PendingCN121758885AEpoxyPolymer science
The invention relates to the technical field of polyvinyl butyral modified materials, and discloses a modified PVB (polyvinyl butyral) material based on nano-silica and a preparation method thereof, the modified PVB material is prepared from the following raw materials by weight: 100 parts of polyvinyl butyral resin; 25 to 45 parts of triethylene glycol di-2-ethylhexoate; 0.5 to 5.0 parts of nano silicon dioxide; 0.05 to 0.50 part of a titanate coupling agent; 0.02 to 0.15 part of magnesium stearate; and 1.0 to 5.0 parts of epoxidized soybean oil. The method comprises the following steps: dispersing silicon dioxide by a plasticizer, dehydrating, adding a coupling agent for in-situ grafting, and compounding a stabilizer to prepare mother liquor; infiltrating the mother liquor into the resin to obtain a swelling material; and performing temperature-controlled extrusion. The modified PVB material based on nano silicon dioxide prepared by the invention solves the problems of particle agglomeration and yellowing, and has high transparency, high strength and excellent heat aging resistance.
Owner:CHENGDU LONGCHENG HIGH TECH MATERIAL

A method for preparing a male health tablet for treating prostatitis

This invention relates to the field of pharmaceutical preparation technology, and particularly to a method for preparing a male enhancement tablet for treating prostatitis. The method optimizes the composition and ratio of auxiliary materials other than the raw medicinal materials. To prepare 2 million tablets of this product, only approximately 1.3 kg of silica, 1.3 kg of magnesium stearate, 90 kg of corn starch, 18 kg of microcrystalline cellulose, 600 kg of ethanol, and 15 kg of gastric-soluble film-coating premix are required. The oil extraction process has also been improved, with the water addition reduced from 6 times the amount of raw materials to 0.4-0.6 kg. The method also changed the process of extracting oil from the medicinal materials by dividing them into eight separate pots for oil extraction. This refined dispersion process greatly saved water consumption and improved the quality of the extracted oil. An additional step of stirring the alcohol precipitation solution for one hour was added to improve the quality of the supernatant. The volatile ether extract of the male health tablets produced by the method of this invention was measured, and the average value of volatile ether extract was found to be 0.53%, which is about 60.6% higher than the 0.33% of the original process, demonstrating significant technological progress.
Owner:SHANXI WANGLONG PHARM GRP CO LTD

High-strength wear-resistant thermoplastic polyurethane composite material and preparation method thereof

PendingCN121450085APolymer scienceAluminum Stearate
The invention belongs to the technical field of polyurethane materials, and particularly relates to a high-strength wear-resistant thermoplastic polyurethane composite material and a preparation method thereof. The high-strength wear-resistant thermoplastic polyurethane composite material provided by the invention is mainly prepared from the following raw materials in parts by mass: 85-92 parts of thermoplastic polyurethane, 5-8 parts of modified spherical calcium carbonate, 1-2.5 parts of aluminum stearate, 0.5-1 part of a surfactant and 0.5-1 part of a crosslinking aid. Through the combined action of the modified spherical calcium carbonate and the magnesium stearate, the shear fracture of a TPU molecular chain can be effectively inhibited, and synchronous improvement of abrasion reduction and mechanical properties is realized. Experiments prove that on the basis of low filler addition amount and low cost, the mechanical strength and wear resistance of the polyurethane composite material are effectively improved, meanwhile, the injection molding characteristic of the material is not affected, and the polyurethane composite material has wide application prospects in bulk TPU application scenarios.
Owner:JIANGSU NUODAO PIPELINE TECHNOLOGY CO LTD

A Tibetan bath composition complex medicament and a preparation method thereof

This invention discloses a Tibetan bath composition compound and its preparation method, relating to the field of daily chemical products technology. The Tibetan bath composition compound consists of a ternary complex of scutellaria baicalensis hydroxypropyl-β-cyclodextrin nanoshell powder, Bacillus subtilis, Tibetan medicine composition, starch, anhydrous citric acid, sodium bicarbonate, calcium citrate, crospovidone, and magnesium stearate. Bacillus subtilis is used to ferment the ternary complex of scutellaria baicalensis hydroxypropyl-β-cyclodextrin nanoshell powder to obtain a fermentation-modified porous carrier, which is then loaded with the Tibetan medicine composition to form a Tibetan medicine inclusion powder. This not only achieves efficient drug delivery through a triple mechanism of biomodification, metabolite synergy, and structural optimization, but also forms a quaternary system with Terminalia chebula. The effervescent effect also enhances the penetration of Tibetan medicine components, which is beneficial for better exerting the antibacterial and anti-inflammatory effects of active substances, and significantly improving fungal infections and eczema-related skin problems.
Owner:ZHEJIANG CHINESE MEDICAL UNIVERSITY

A zhi-shu yang-wei tablet for chronic gastritis and a dry compression tablet process of granules thereof

PendingCN122297623ABiotechnologySucrose
This invention discloses a Zhishu Yangwei tablet for chronic gastritis and its granule dry-compression tableting process, relating to the field of traditional Chinese medicine preparation technology. The Yangwei tablet is made from the following raw materials in parts by weight: Codonopsis pilosula 35-45 parts, stir-fried Atractylodes macrocephala 18-22 parts, Poria cocos 18-22 parts, Glycyrrhiza uralensis 8-12 parts, Amomum villosum 18-22 parts, Lindera strychnifolia 18-22 parts, Salvia miltiorrhiza 45-55 parts, roasted Aucklandia lappa 18-22 parts, Paeonia lactiflora 18-22 parts, stir-fried Citrus aurantium 18-22 parts, Magnolia officinalis 28-32 parts, Lilium brownii 35-45 parts, and stir-fried chicken gizzard lining 18- 22 parts, dried plum 45-55 parts, Coptis chinensis 8-12 parts, hawthorn 35-45 parts, magnesium stearate 5-7 parts, sucrose 28-32 parts; This invention uses low-temperature dynamic extraction technology to replace the traditional high-temperature decoction process, effectively reducing the decomposition loss of heat-sensitive active ingredients such as tanshinone IIA and ursolic acid, and improving the bioavailability of the drug. It also uses membrane concentration and spray drying technology to replace the traditional atmospheric pressure concentration and oven drying process, shortening the production cycle, reducing energy consumption, and avoiding the degradation of active ingredients caused by prolonged heating of materials.
Owner:SHIZHONG DISTRICT TRADITIONAL CHINESE MEDICINE HOSPITAL OF LESHAN CITY

Candesartan cilexetil capsule and preparation method thereof

PendingCN121987583Afix stability issuesAvoid the possibility of crystallizationOrganic active ingredientsPharmaceutical non-active ingredientsCelluloseCaplet Dosage Form
The invention provides a candesartan cilexetil capsule and a preparation method thereof, and the candesartan cilexetil capsule is characterized in that each capsule contains candesartan cilexetil, lactose, corn starch, hydroxypropyl cellulose, carboxymethyl cellulose calcium, polyethylene glycol 8000 and magnesium stearate. According to the candesartan cilexetil capsule provided by the invention, the problem of stability of candesartan cilexetil is solved, the possibility of crystal transformation of common tablets in a tabletting process is reduced, and the characteristic dissolution curve of a final product is similar to that of a reference preparation; the preparation method is simple in process route, the fluidized bed one-step granulation method enables the loss to be less, the product yield is higher, and the industrial mass production cost is reduced.
Owner:珠海润都制药股份有限公司

Sublingual tablet and application thereof in desensitization therapy drug

PendingUS20260027044A1Peptide/protein ingredientsAllergen ingredientsLow-substituted hydroxypropylcelluloseMagnesium stearate
A sublingual tablet and application thereof in desensitization therapy drug are provided. The sublingual tablet is a low-dose allergen sublingual tablet. The sublingual tablet includes freeze-dried powder of allergen protein, lactose, mannitol, low substituted hydroxypropyl cellulose, low moisture microcrystalline cellulose, and magnesium stearate. The freeze-drying process is adopted to obtain the freeze-dried powder of allergen protein, and the powder direct compression technology is adopted to obtain the sublingual tablet of allergen protein. The low-dose sublingual tablet has excellent properties, including appearance, hardness, tablet weight variation, disintegration time, taste, and uniformity of content, in particular has outstanding advantages in disintegration time, uniformity of content, stability, and preparation process, and has an industrial application prospect.
Owner:ZONHON BIOPHARMA INST

Traditional Chinese medicine preparation for treating pleural effusion and peritoneal effusion and preparation method thereof

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine preparation for treating pleural effusion and peritoneal effusion and a preparation method thereof.The traditional Chinese medicine preparation is prepared from, by weight, 10-50 parts of traditional Chinese medicine extract, 30-70 parts of filler, 5-20 parts of enteric coating material, 5-15 parts of HPMC, 0.5-2 parts of triethyl citrate and 0.25-1.5 parts of magnesium stearate; poria cocos, polyporus umbellatus, rhizoma alismatis, astragalus membranaceus, curcuma zedoary, cassia twig, oldenlandia diffusa, sculellaria barbata, semen coicis and traditional Chinese medicine extracts are used as cores, the stability of volatile drugs is improved through an inclusion technology, and the volatile drugs are entrapped in a pH intelligent response type enteric coating material composed of aromatic ring-containing vinyl monomers, ethyl acrylate, DMAEMA and MAA. The traditional Chinese medicine preparation has the synergistic effect of efficiently inducing diuresis, activating blood circulation and eliminating tumors and enteric-coated long-acting directional delivery, and is suitable for patients with pleural effusion and peritoneal effusion, especially malignant effusion.
Owner:GUOJINGTANG (BEIJING) MEDICAL TECHNOLOGY CO LTD

Preparation method and application of nano organic pigments with different crystal forms

PendingCN121975348AEnsure control accuracyhigh purityQuinacridonesInorganic saltsWeather resistance
The invention relates to the field of organic pigments, and discloses a preparation method and application of nano organic pigments with different crystal forms. The preparation method comprises the following steps: 1) dissolving an organic pigment crude product in a good solvent, and adding inorganic salt for activation; 2) dropwise adding a poor solvent at a gradient rate, adding a crystal form guiding agent, and inducing formation of a crystal nucleus; wherein the alpha crystal form directing agent is magnesium stearate; the beta crystal form directing agent is dibutyl phthalate; the gamma crystal form directing agent is polyethylene glycol; the initial gradient rate is 0.5-1 mL / min, and the gradient rate is increased by 0.2-0.3 mL / min every 8-12 min; 3) ultrasonic treatment; 4) cooling, and adding a surface modifier for surface modification; according to the preparation method, the nanometer organic pigment with the target crystal form can be accurately obtained through process regulation and control, the nanometer organic pigment is uniform in particle size distribution, good in dispersity, good in heat-resistant stability and high in color and luster strength, and the nanometer organic pigment has the advantages of being good in flocculation-resistant stability and weather resistance after a coating is formed.
Owner:HANGZHOU BAIHE CLARIANT PIGMENTS CO LTD +1

Three-ply base double-channel prefabricated waterproofing roll with hook-and-loop fastener

The present application relates to waterproofing membrane technical field, propose a kind of three base double-channel prefabricated bite lap waterproofing membrane with touch fastener, from bottom to top, in turn include anti-adhesive layer, first permeation reaction adhesive layer, first polymer film base layer, second permeation reaction adhesive layer, second polymer film base layer, third permeation reaction adhesive layer, third polymer film base layer, fourth permeation reaction adhesive layer, rough surface silk layer and hook face layer;The adhesive of first permeation reaction adhesive layer, second permeation reaction adhesive layer, third permeation reaction adhesive layer and fourth permeation reaction adhesive layer respectively independently includes following weight parts component raw materials: asphalt, softener, SBS, SIS, tackifier, rubber powder, filler, filler is composed of heavy calcium carbonate, magnesium stearate modified active calcium carbonate and hollow glass microsphere.By the above technical solution, the problem of poor fixing, low peel strength and heavy quality of waterproofing membrane in related art is solved.
Owner:HEBEI YUYANGZELI WATERPROOF MATERIAL

A film-coated tablet of jujube seed and Ganoderma lucidum and its preparation method

This application discloses a jujube seed and Ganoderma lucidum film-coated tablet and its preparation method. The film-coated tablet uses jujube seed and Ganoderma lucidum in a weight ratio of (2.9–3.1):2 as active raw materials, employs a microcrystalline cellulose and erythritol compound as fillers, and combines them with silica, magnesium stearate, and a specific composite film-coating agent. The preparation method includes raw material pretreatment, water extraction, vacuum concentration, vacuum drying, fluidized bed granulation, total mixing and tableting, and film coating, optimizing each process parameter. This application solves the technical problems of existing traditional Chinese medicine extracts, such as high hygroscopicity, poor compressibility, poor stability, and unclear synergistic effects. The prepared product has high active ingredient content, good stability, rapid disintegration, and good patient compliance, making it suitable for large-scale industrial production and possessing good market application prospects.
Owner:HEBEI JINMU PHARM GRP CO LTD

Preparation method of solid waste-based early strength marine cement-based material

ActiveCN121948921BPhysical chemistryCarbide
The application relates to the field of marine cement materials, and particularly discloses a preparation method of a solid-waste-based early-strength marine cement-based material, which comprises the following steps: (1) uniformly mixing calcined recycled concrete micro powder and magnesium oxide whiskers, then mixing the mixture with water to form wet materials, and then standing; after hardening, crushing and grinding the obtained solidified body to obtain modified recycled micro powder; (2) uniformly mixing the modified recycled micro powder with a hot isopropyl alcohol solution of a stearate to obtain a waterproof agent after drying; (3) uniformly mixing magnesium oxide whiskers with a hot isopropyl alcohol solution of magnesium stearate to obtain modified magnesium oxide whiskers after drying; (4) uniformly mixing potassium dihydrogen phosphate, the waterproof agent and the modified magnesium oxide whiskers to obtain an early-strength agent; and (5) uniformly mixing granulated blast furnace slag powder, fly ash, solid-waste-based gypsum powder, carbide slag powder, coarse aggregate, fine aggregate, a water reducing agent, the early-strength agent and mixing water to obtain the solid-waste-based early-strength marine cement-based material. The early-strength additive can not only improve the early strength of the solid-waste-based cement-based material, but also improve the adaptability to the marine environment.
Owner:CCCC SIGONG CONSTR TECH (JINAN) CO LTD +1

Salt baked flavor chicken energy chewable tablet and preparation method thereof

PendingCN122070827AAvoid sweet and greasy tasteunique flavorFood shapingBiotechnologyNutrition
The invention discloses salt baked flavor chicken energy chewable tablets and a preparation method thereof, and belongs to the technical field of food processing. The chewable tablet consists of the following components in percentage by weight: 20-40 parts of salt roasted chicken powder, 25-50 parts of an energy supplement, 0.1-0.5 part of composite vitamins, 10-30 parts of an excipient, 0.5-2 parts of a flavoring agent, 0.1-0.5 part of an antioxidant, 1-3 parts of magnesium stearate and the balance of deionized water. The salt-baked chicken powder is prepared by taking chicken breast as a raw material, rolling, kneading and pickling with a salt-baked flavor pickling solution, steaming, drying and pulverizing. According to the invention, the salt baked flavor and the nutrition of chicken are combined, the salty and fragrant flavor and balanced nutrition are combined, rapid and lasting energy supplementation can be realized, the chewable tablet is portable to eat, is subjected to dry granulation, low-temperature sterilization and aluminum foil packaging, has long shelf life, adopts a natural flavoring agent, is high in safety, and is suitable for various energy supplementation scenes such as sports, offices, outdoors and the like.
Owner:SOUTH CHINA UNIV OF TECH

Florfenicol preparation capable of reversing drug resistance and preparation method of florfenicol preparation

The invention relates to a florfenicol preparation for reversing drug resistance, and every 100 kg of the florfenicol preparation is prepared from the following raw materials by weight: 30 to 50 kg of florfenicol, 5 to 10 kg of puerarin, 0.5 to 1 kg of magnesium stearate, and the balance of silicon dioxide. The florfenicol preparation is subjected to low-temperature crushing treatment, the crystal form of the medicine can be prevented from being converted, the dissolution rate of the medicine is prevented from being reduced, the florfenicol and the puerarin are reasonably proportioned according to the formula, the optimal reverse drug resistance effect is achieved, and meanwhile, the product process is particularly suitable for industrial production.
Owner:FEIMO (NANYANG) BIOTECHNOLOGY CO LTD +2

Tabletting candy capable of inhibiting fat absorption and preparation method thereof

The invention provides a tablet candy capable of inhibiting fat absorption and a preparation method of the tablet candy, and relates to the technical field of functional foods. The pressed candy capable of inhibiting fat absorption comprises 0.1-25 parts of flammulina velutipes powder, 1-18 parts of L-arabinose, 0.05-5 parts of carob gum, 0.1-12 parts of chestnut powder, 0.1-10 parts of seaweed meal, 0.1-10 parts of instant oolong tea powder, 1-15 parts of composite vegetable powder, 30-80 parts of sorbitol, 3-15 parts of whole milk powder, 0.1-10 parts of edible mushroom concentrated powder, 1-10 parts of yoghurt powder, 1-15 parts of juicy peach juice powder and 0.1-2 parts of citric acid. And 0.1 to 1.5 parts of magnesium stearate. Various functional components such as beta-glucan and L-arabinose in the flammulina velutipes have a synergistic effect, so that the fat adsorption rate is increased; by means of the cold granulation and low-temperature tabletting technology, the retention rate of active ingredients is increased, meanwhile, the product has excellent stability and safety and good taste, the effects of improving intestinal flora and regulating blood sugar can be achieved, and important technical value and wide application prospects are achieved.
Owner:SHANGHAI BAIXIANXIAN BIOTECHNOLOGY CO LTD

Doxazosin mesylate sustained-release tablet and preparation process thereof

The invention discloses a doxazosin mesylate sustained-release tablet and a preparation process thereof, and relates to the technical field of doxazosin mesylate sustained-release tablets.The sustained-release tablet comprises a double-layer tablet core composed of a first sustained-release layer and a second sustained-release layer; the double-layer tablet core is prepared from the following components in parts by mass: a first slow-release layer and a second slow-release layer; the first slow-release layer is prepared from the following components in parts by mass: 2.4 parts of chitosan-TPP modified doxazosin mesylate, 10 to 12.5 parts of citric acid-cassava starch, 12.5 to 15 parts of magnesium aluminum silicate-cassava starch, 40 to 60 parts of microcrystalline cellulose and 3 to 4 parts of magnesium stearate; the second slow-release layer is prepared from the following components in parts by weight: 2.4 parts of chitosan-TPP modified doxazosin mesylate, 1.44 to 3.36 parts of carrageenan, 130 to 140 parts of polyethylene oxide, 30 to 40 parts of sodium alginate, 55 to 65 parts of citric acid, 67 to 77 parts of microcrystalline cellulose and 3 to 4 parts of magnesium stearate.
Owner:ANRUOWITA PHARM TAIZHOU CO LTD

Dietary therapy formula for preventing senile dementia, improving memory, repairing conducted nervous system and dredging damaged brain nerves

The invention discloses a dietary therapy formula for preventing senile dementia, improving memory, repairing a conducted nervous system and dredging damaged brain nerves, and belongs to the technical field of dietary therapy health care. According to the formula, functional nutritional ingredients, bioactive peptides, medicinal and edible extracts and compound probiotics are taken as cores, and the formula is prepared through scientific proportioning; the health-care food specifically comprises xylitol, isomaltooligosacharide, N-acetylneuraminic acid, phosphatidylserine, bovine brain peptide, walnut peptide, shark peptide, acer truncatum seed oil microcapsule powder, DHA algal oil microcapsule powder, spina date seeds, tea theanine, gamma-aminobutyric acid, Belgian imported inulin, magnesium stearate, and 16 optional specific probiotics and metabiotics. The formula follows a multi-dimensional synergistic principle of nutrition supply-nerve repair-function regulation-absorption synergy, the core component can penetrate through a blood brain barrier, supplement nerve repair raw materials, repair damaged nerve cells and myelin sheaths and regulate neurotransmitter balance, and the probiotics indirectly assist nerve maintenance through intestinal tract-nerve axis, so that the composition has the effects of promoting blood circulation and promoting blood circulation. The synergistic effects of preventing senile dementia, improving memory and repairing and dredging a nervous system are achieved; the raw materials are food-grade safe components, have no side effects, can be prepared into powder, tablet candies and other forms, are convenient to eat and suitable for long-term conditioning, and solve the problems of single component, insufficient repair pertinence and low absorption efficiency of existing nerve care products.
Owner:SHANDONG YUPIN TIANDAN MARINE BIOTECHNOLOGY CO LTD

Mongolian medicine tablet as well as preparation method and application thereof

The invention provides a Mongolian medicine tablet which is characterized by comprising extract powder prepared from herba violae, rhizoma picrorhizae, fructus gardeniae and dianthus superbus, silica gel, lactose, magnesium stearate, povidone and a coating layer. The invention also provides a preparation method of the Mongolian medicine tablet. The preparation method is characterized by comprising the following steps: (1) preparing extract powder; (2) preparing a tablet core; and (3) preparing a coating layer. The invention further provides application of the Mongolian medicine tablet in preparation of a medicine for treating cholecystitis.
Owner:INNER MONGOLIA UNIV FOR THE NATITIES

Shock energy resistant copper-based composite metal block, preparation process and application thereof

PendingCN122446000ALithium stearateMagnesium stearate
The application relates to the application field of metal powder metallurgy technology and discloses a copper-based composite material metal block capable of resisting impact energy and a preparation process and application thereof. The copper-based composite material metal block is used in impact and collision process tests, and impact energy absorption, reduction or elimination is realized by self-pulverization and disintegration. Raw materials of the copper-based composite material capable of resisting impact energy include, in percentage by mass, 1-95% of atomized copper powder, 0-95% of electrolytic copper powder, 1-15% of tin powder, 1-2% of molybdenum disulfide, 0-3% of graphite, 0-7% of phenolic resin, 0-1% of lithium stearate and 0-1% of magnesium stearate. The above raw materials are mixed, secondarily pressed, sintered and electroplated to form the copper-based composite material. When encountering an impacted metal barrier section, the metal block can absorb the counter-impact energy and disintegrate by itself, so that the running speed instantaneously drops to zero, the metal fragment splashing phenomenon does not occur, and the copper-based composite material does not contain lead metal, so that the whole impact and collision process is harmless to the surrounding environment.
Owner:SUZHOU PENTAGRAM TECHNOLOGY CO LTD

Rumen bypass choline chloride particle and preparation method thereof

The invention discloses rumen bypass choline chloride particles and a preparation method thereof, and belongs to the technical field of feed additives. The rumen bypass choline chloride particle comprises a drug-loading inner core and an outer protective layer coating the drug-loading inner core, the drug-loading inner core is obtained by mixing hydrophobic particles with a melt, extruding and granulating; wherein the hydrophobic particles are obtained by wrapping crystal form choline chloride with a hydrophobic material; the molten liquid is obtained by melting and mixing stearic acid, magnesium stearate and oleophylic cellulose; the oleophylic cellulose adopts ethyl cellulose; the outer protective layer is obtained by mixing fatty acid, hydrogenated grease, a pH sensitive material and a fragrant raw material with fruit fragrance, green grass fragrance or fermentation fragrance; the outer protective layer of the rumen bypass choline chloride particle is good in toughness and fitness, the rumen bypass choline chloride particle is good in rumen bypass effect and good in small intestine release rate, the food intake of dairy cows is not affected, the risk of metabolic diseases is effectively reduced, and the health level of the dairy cows is improved.
Owner:SHANGHAI MEINONG FEED CO LTD

A sustained-release composition of tranexamic acid and a preparation process and application thereof

This invention belongs to the field of biopharmaceutical technology and discloses a tranexamic acid sustained-release composition, its preparation process, and its application. By weight, the composition comprises 100-120 parts tranexamic acid, 14-18 parts sustained-release material, 5-8 parts magnesium stearate, 2-5 parts colloidal silica, and 3-5 parts polyvinyl alcohol. The sustained-release material is selected from a combination of hydroxypropyl cellulose and ethyl cellulose, or a combination of hydroxypropyl methyl cellulose and microcrystalline cellulose, or a combination of sodium carboxymethyl cellulose and hydrogenated vegetable oil. This invention utilizes the synergistic effect of the sustained-release material and the synergistic effect between the sustained-release material and polyvinyl alcohol to maintain zero-order or first-order release of the drug, achieving a steady-state blood drug concentration and prolonging the duration of action, thereby achieving a good sustained-release effect.
Owner:南方医科大学第五附属医院

Nutrient composition for promoting hair growth and preparation method thereof

The invention relates to the field of hair growth nutrients, and discloses a nutrient composition for promoting hair growth and a preparation method thereof, the composition comprises a basic hair growth nutrient group and an absorption-promoting synergistic group; the basic hair growth nutrition group comprises the following components in parts by weight: 0.3-0.8 part of ferrous lactate, 2-5 parts of zinc gluconate, 5-8 parts of magnesium stearate, 3-8 parts of a coating material and 17-25 parts of milk mineral salt; the absorption-promoting synergistic group comprises the following components in parts by weight: 0.2-1.5 parts of a black pepper extract, 2-10 parts of lecithin and 2-8 parts of casein phosphopeptides, the black pepper extract and the lecithin are firstly released, an intestinal epithelium channel is opened by utilizing a biological penetration promoting effect, and a pre-permeation state is established; the subsequently released CPP is complexed with divalent metal ions in intestinal juice to prevent precipitation, so that the CPP is synchronously and rapidly absorbed through a pre-opened channel, and the problems of competitive antagonism and difficult absorption of high-dose minerals are effectively solved.
Owner:AFFILIATED HUSN HOSPITAL OF FUDAN UNIV +1