Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

329 results about "Magnesium stearate" patented technology

Magnesium stearate is the chemical compound with the formula Mg(C₁₈H₃₅O₂)₂. It is a soap, consisting of salt containing two equivalents of stearate (the anion of stearic acid) and one magnesium cation (Mg²⁺). Magnesium stearate is a white, water-insoluble powder. Its applications exploit its softness, insolubility in many solvents, and low toxicity. It is used as a release agent and as a component or lubricant in the production of pharmaceuticals and cosmetics.

A pulverization process of a derivative biomass hard carbon material

The application discloses a kind of derived biomass hard carbon material pulverization process, belong to biomass charcoal material processing technical field, first, pulverization process includes the following steps: after drying, the coconut shell derived hard carbon block is carried out primary crushing, while spraying first modifier, obtain the particle size 1~3mm of coarse crushing modified particle;Coarse crushing modified particle is carried out secondary precision crushing under argon atmosphere, while spraying second modifier, obtain the precision crushing modified particle of D 50 Particle size is 15 μm;Precision crushing modified particle is carried out roll grinding spheroidization, while spraying third modifier, obtain the spherical modified particle of D 50 Particle size is 10 μm;Spherical modified particle is carried out flash drying after cooling, then add magnesium stearate to it, after mixing, obtain derived biomass hard carbon material.Then, the application realizes breakthrough in tap density, particle size distribution, first efficiency and other core indexes by the coordination of three-stage gradient modification and progressive pulverization process.
Owner:HUAXIAN DACHAOLIN BUSSAN

Polygonatum sibiricum and saussurea involucrate bone marrow peptide tablet as well

The invention relates to the technical field of functional product preparation, and provides a rhizoma polygonati and saussurea involucrata bone marrow peptide tablet as well as a preparation method and application thereof. The rhizoma polygonati and saussurea involucrata bone marrow peptide tablet is prepared from the following components: collagen peptide powder, L-isoleucine, a compound nutrient supplement, rhizoma polygonati, sorbitol, yak bone marrow peptide powder, fructus phyllanthi, fructus alpiniae oxyphyllae, mulberry powder, a saussurea involucrata culture and magnesium stearate. All the components of the rhizoma polygonati and saussurea involucrata bone marrow peptide tablet disclosed by the invention have a synergistic effect, so that the effects of conditioning sub-health, maintaining joints and assisting in treating diseases can be achieved.
Owner:SHIJIAZHUANG ZANGNUO BIOTECH

Preparation method and application of hydroxypropyl carboxymethyl composite starch ether with low bath ratio and high viscosity

ActiveCN120737220ADyeing processSodium acetateSodium chloroacetate
The invention provides a preparation method and application of low-bath-ratio and high-viscosity hydroxypropyl carboxymethyl composite starch ether, and relates to the technical field of starch deep processing. The method comprises the following steps: S1, premixing corn starch with a compound base catalyst and magnesium stearate, and spraying an ethanol water solution for alkalization; s2, adding epoxypropane to carry out first-stage etherification, and then adding sodium chloroacetate to carry out second-stage etherification; and S3, after the reaction is finished, performing vacuum drying, crushing and sieving to obtain the high-viscosity hydroxypropyl carboxymethyl composite starch ether. Wherein the composite alkali catalyst comprises sodium hydroxide, sodium carbonate and calcium oxide. The starch ether obtained by the method has the advantages of high substitution degree, high viscosity, low solvent consumption and low energy consumption, and overcomes the defects of the traditional semi-dry method.
Owner:SHANDONG GUANGDA SAILU NEW MATERIALS TECHNOLOGY CO LTD

Solid dispersion-based sustained-release drug composite carrier as well as preparation method and application thereof

The invention relates to the technical field of pharmaceutical preparations, in particular to a solid dispersion-based sustained-release drug composite carrier as well as a preparation method and application thereof. The preparation method comprises the following steps: carrying out synergistic spray drying on double polymers (hydroxypropyl methylcellulose acetate succinate and polyvinylpyrrolidone-vinyl acetate copolymer) to form a solid dispersion; compounding with mesoporous silica and calcium silicate for localization, and spraying ethanol to activate pores; calcium stearate and magnesium stearate are sequentially added for lubrication; prefabricating a sustained-release skeleton master batch; and finally, mixing, rolling and forming. According to the method, through hierarchical structural design, the drug stability, the powder fluidity and the release controllability are remarkably improved, the method is suitable for industrial production of the dihydroergoline mesylate sustained release preparation, and a release curve is smooth and reliable.
Owner:宝利化(南京)制药有限公司

Plasmin lumbrukinase peptide dietary therapy formula suitable for rehabilitation of cardiovascular and cerebrovascular diseases, blood circulation promotion, stasis removal, thrombolysis, collateral dredging and microcirculation improvement

The invention discloses a plasmin lumbrukinase peptide dietary therapy formula suitable for rehabilitation of cardiovascular and cerebrovascular diseases, blood circulation promoting, blood stasis removing, thrombolysis, collateral dredging and microcirculation improving, and relates to the technical field of medicine and food homology dietary therapy. Soybean protein isolate and earthworm protein are used as core thrombolytic active raw materials, isomaltooligosacharide, xylitol, German Jilida collagen peptide, soybean peptide powder, Belgian imported inulin, red yeast rice and natto powder are compounded, microcrystalline cellulose and magnesium stearate are used as auxiliary materials, and probiotics / metabiotics strains such as rhamnolactobacilli JYLR-005 and the like can be selectively added. The raw materials have a synergistic effect through precise matching, plasmin and lumbrukinase peptide in earthworm protein can directly dissolve thrombus fibrin, natto powder and red yeast rice assist in lowering lipid and dissolving thrombus, multiple active peptides and prebiotics regulate intestinal microecology to improve microcirculation of the whole body, probiotics / metabiotics further strengthen the metabolic capacity of the body, no chemical medicine is added in the whole process, and the traditional Chinese medicine composition is free of toxic and side effects and free of toxic and side effects. The safety is high; the dietary therapy composition can achieve postoperative rehabilitation conditioning of cardiovascular and cerebrovascular diseases through daily consumption, effectively promote blood circulation to remove blood stasis, dissolve thrombus and dredge collaterals, improve microcirculation and relieve various discomfort caused by blood vessel clogging, raw materials are easy to obtain, compatibility is scientific, and the dietary therapy composition is suitable for large-scale production and popularization.
Owner:SHANDONG YUPIN TIANDAN MARINE BIOTECHNOLOGY CO LTD

High-color-fastness washable polyethylene fabric and preparation process thereof

The invention discloses a high-color-fastness washable polyethylene fabric and a preparation process thereof in the field of functional polymer materials. The high-color-fastness washable polyethylene fabric is prepared from the following raw materials: polyethylene resin, maleic anhydride-acrylic acid copolymer grafted polyethylene, dopamine-silane composite modified polyethylene, magnesium stearate and an antioxidant. Wherein the maleic anhydride-acrylic acid copolymer grafted polyethylene is prepared by copolymerizing maleic anhydride and acrylic acid and then blending and granulating with polyethylene, and carboxyl and acrylate groups are introduced to enhance the binding force with dye; the dopamine-silane composite modified polyethylene is prepared through polyethylene surface hydroxylation, dopamine self-polymerization modification and silane grafting reaction, and the acting force and hydrophobicity between fibers are doubly improved through a catechol group and an epoxy group. According to the prepared fabric, the color fastness and the washing resistance are remarkably improved, meanwhile, the original characteristics of light weight and chemical corrosion resistance of polyethylene are kept, and the application scene is expanded.
Owner:BIEM L FDLKK GARMENT CO LTD

Fiber-based food containers for emulsions

Systems and methods are described for fiber-based, plastic-free products for storage of emulsion food products. In some embodiments, a coating is applied to the product, such as a coating comprising efficacious proportions of xylitol, citric acid, water, microfibrillated cellulose, and polyvinyl alcohol. A slurry is used to fabricate the product includes various proportions of fiber blends (e.g., combinations of bleached softwood, bleached hardwood, kraft paper, and / or virgin fiber), AKD, starch, a stearate (e.g., Magnesium or Calcium Stearate), a defoamer, and microfibrillated cellulose.
Owner:FOOTPRINT INT LLC

Anti-aging capsule compounded by PQQ and mitochondrial nutrients

The invention relates to an anti-aging capsule compounded by PQQ and mitochondrial nutrients, and discloses an anti-aging capsule which is prepared by synergistically compounding a plurality of mitochondrial nutrients according to a scientific proportion and supplementing high-purity raw materials and slow-release dosage forms to realize energy metabolism activation and anti-oxidation synergistic intervention. Therefore, the anti-aging capsule systematically delays aging through multi-target regulation and control of mitochondrial functions. The capsule is characterized by comprising the following components in parts by weight: 1-20 mg of pyrroloquinoline quinone disodium salt (PQQ), 20-100 mg of coenzyme Q10, 50-200 mg of L-carnitine tartrate, 10-100 mg of alpha-lipoic acid, 50-300 mg of nicotinamide mononucleotide (NMN) or nicotinamide nucleoside (NR), and 10-50 [mu] g of selenoprotein or organic selenium yeast, and a capsule carrier comprises 100 mg of gelatin or a plant-derived capsule shell, 180 mg of microcrystalline cellulose, 5 mg of magnesium stearate and 5 mg of silicon dioxide.
Owner:JIANGSU SHAREJOY HEALTH TECH CO LTD

Astragaloside synergistic composition as well as preparation method and application thereof

The invention discloses an astragaloside synergistic type composition as well as a preparation method and application of the astragaloside synergistic type composition. Comprising the following components: 8 to 16 parts of astragaloside, 20 to 40 parts of a honeysuckle flower extract, 10 to 20 parts of L-carnitine, 0.1 to 0.5 part of selenium yeast, 3 to 8 parts of diammonium glycyrrhizinate, 5 to 15 parts of taurine, 8 to 20 parts of a fructus forsythiae extract, 2 to 7 parts of vitamin E, 12 to 32 parts of hydroxypropyl-beta-cyclodextrin, 2 to 10.5 parts of maltodextrin, 1 to 7 parts of Arabic gum, 10 to 20 parts of lactose, 1 to 3 parts of zinc gluconate and 2 to 5 parts of magnesium stearate. 1-3 parts of vitamin C, 1-5 parts of xanthan gum and 1-3 parts of lecithin. The composition has a wide application prospect in preparation of veterinary drugs or veterinary food additives.
Owner:JIANGXI CHENGBIXIN BIOTECHNOLOGY CO LTD

Sustained-release pellet particles containing gamma-aminobutyric acid and preparation method of sustained-release pellet particles

PendingCN121714541AOrganic active ingredientsNervous disorderSustained release pelletsAlcohol sugars
The invention provides a sustained-release pellet containing gamma-aminobutyric acid, the sustained-release pellet comprises a pellet core and a coating layer wrapping the pellet core, the pellet core contains a physiologically active substance, and the physiologically active substance is gamma-aminobutyric acid; the pellet core comprises the following components in parts by weight: 15-40 parts of gamma-aminobutyric acid, 30-55 parts of a filling agent, 1-30 parts of a lubricating agent and 0.5-5 parts of an anti-caking agent; the filling agent comprises at least one of microcrystalline cellulose, powdery cellulose, starch and derivatives thereof, hydroxypropyl cellulose, hydroxypropyl methylcellulose, low-substituted hydroxypropyl cellulose, sugar or sugar alcohol and fruit and vegetable powder; the lubricant comprises at least one of talcum powder, magnesium stearate, stearic acid, glycerol and leucine; the anti-caking agent comprises at least one of magnesium carbonate, tricalcium phosphate, calcium hydrophosphate and silicon dioxide.
Owner:XIAN LE JIAN KANG KE JI (GUANG DONG) YOU XIAN GONG SI

Heart and cerebral vessel health care composition with thrombolytic and antithrombotic functions and preparation method thereof

The invention relates to the technical field of food processing, and particularly discloses a heart and cerebral vessel health care composition with thrombolytic and antithrombotic functions and a preparation method thereof. The composition consists of the following raw materials: sorbitol, red yeast rice, freeze-dried natto powder, earthworm protein peptide, vitamin C, American ginseng peptide, magnesium stearate, an angelica sinensis extract, rice bran fatty alkanol, vitamin B1, vitamin B2, a turmeric extract and a compound coloring agent. The preparation method comprises the following steps: mixing the raw materials except magnesium stearate in a double-cone mixer; magnesium stearate is added for continuous mixing, and a hollow capsule shell is filled with the mixed material. The composition disclosed by the invention forms a multi-dimensional synergistic system for smoothing blood vessels, purifying blood and improving blood flow, the defect of single effect of an existing product is overcome, the health-care effect of heart and cerebral vessels is remarkably improved, and the effect is stable and controllable; in addition, the preparation method has the advantages of being simple and controllable in process and suitable for industrial production.
Owner:JIUJIANG KUNHAO TRADING CO LTD

Preparation method of ceramic filler powder and porous ceramic

The invention discloses ceramic filler powder and a preparation method of porous ceramic, and relates to the technical field of ceramic. According to the invention, the raw material components are reasonably proportioned, and the superfine SiC-coated MgAl-LDH compound is used as an additive to be mixed with kaolin, potassium feldspar, quartz, aluminum oxide, silicon carbide and talc to prepare the ceramic filler powder. On the basis, the prepared ceramic filler powder is mixed with carboxymethyl cellulose, polyvinyl alcohol, water glass, magnesium stearate and water, then the mixture is subjected to filter pressing, vacuum pugging and aging, and then the porous ceramic is prepared through a forming process and a sintering process. The porous ceramic prepared from the ceramic filler powder provided by the invention has better compressive strength and corrosion resistance, is beneficial to expanding the application field of products, and particularly meets the requirements of high-end industries.
Owner:PINGXIANG HENGXI CHEM PACKING CO LTD

A bucumlan tablet and a method for preparing the same

The application discloses a kind of bumetanide tablets, raw materials include bumetanide 1 according to mass ratio;Corn starch 81~85;Lactose 50~54;Agar 0.1~0.3;Povidone K304~6;Polysorbate 80, 0.1~0.2;Silicon dioxide 3~4.5;Talcum powder 2~3.3;Magnesium stearate 0.3~0.7.Its preparation method includes the following steps: pretreatment, premixing, granulation, wet granulation, drying, dry granulation, total mixing, tabletting and packaging.The application introduces the synergistic system of trace agar and polysorbate 80 in the prescription.Agar, as a natural hydrophilic colloid, can form a hydrophilic network structure during the granulation process, and synergistically act with polysorbate 80, greatly improving the wettability and dispersibility of the slurry to ultrafine bumetanide, preventing drug agglomeration, so that the drug can be more evenly distributed in the granules during the subsequent drying and tabletting process.
Owner:JIANGSU SHENLONG PHARMA

A sustained-release bupropion hydrochloride preparation and a method for preparing the same

The application provides a bupropion hydrochloride sustained-release tablet and a preparation method, and belongs to the technical field of pharmacy. The pharmaceutical composition contains 150 parts of bupropion hydrochloride, 122.5-157.5 parts of glycerin monostearate, 17.5-22.5 parts of triethyl citrate, 68-104 parts of microcrystalline cellulose and 2-6 parts of magnesium stearate, wherein the bupropion hydrochloride raw material and the glycerin monostearate and the triethyl citrate are prepared into a solid dispersion through a hot melt extrusion process. The application provides a bupropion hydrochloride sustained-release tablet which is stable in drug release, slow in growth of related substances, does not need to be coated and can be taken and eaten, and a preparation method.
Owner:DISHA PHARMA GRP

Long-acting antistatic glass fiber reinforced polypropylene composite material as well as preparation method and application thereof

The invention provides a long-acting antistatic glass fiber reinforced polypropylene composite material as well as a preparation method and application thereof. The long-acting antistatic glass fiber reinforced polypropylene composite material is prepared from the following components in parts by weight: 70 to 90 parts of glass fiber reinforced polypropylene, 10 to 20 parts of antistatic master batch, 0.1 to 0.5 part of antioxidant and 0.5 to 1 part of magnesium stearate, wherein the antistatic master batch comprises the following components in parts by weight: 80-85 parts of a polypropylene base material, 15-20 parts of nano ATO, 2-3 parts of a polyethylene wax dispersing agent and 0.5-1 part of a lubricating agent. According to the invention, the nano ATO is pre-dispersed in the antistatic master batch and then is subjected to synergistic copolymerization with a glass fiber network in the glass fiber reinforced polypropylene, and the surface resistivity of the composite material can be reduced to 106-108 omega.cm through a small addition amount. Compared with carbon black and other traditional fillers in the prior art, the addition amount of the nano ATO in the application is small, so that the surface resistivity of the composite material can be reduced to 10 < 6 >-10 < 8 > omega.cm, and the surface resistivity of the composite material can be reduced to 10 < 6 >-10 < 8 > omega.cm. The density, the color and the mechanical property of the composite material are not influenced.
Owner:ZHUHAI GREE NEW MATERIAL CO LTD

Modified PVB (Polyvinyl Butyral) material based on nano silicon dioxide and preparation method of modified PVB material

PendingCN121758885AEpoxyPolymer science
The invention relates to the technical field of polyvinyl butyral modified materials, and discloses a modified PVB (polyvinyl butyral) material based on nano-silica and a preparation method thereof, the modified PVB material is prepared from the following raw materials by weight: 100 parts of polyvinyl butyral resin; 25 to 45 parts of triethylene glycol di-2-ethylhexoate; 0.5 to 5.0 parts of nano silicon dioxide; 0.05 to 0.50 part of a titanate coupling agent; 0.02 to 0.15 part of magnesium stearate; and 1.0 to 5.0 parts of epoxidized soybean oil. The method comprises the following steps: dispersing silicon dioxide by a plasticizer, dehydrating, adding a coupling agent for in-situ grafting, and compounding a stabilizer to prepare mother liquor; infiltrating the mother liquor into the resin to obtain a swelling material; and performing temperature-controlled extrusion. The modified PVB material based on nano silicon dioxide prepared by the invention solves the problems of particle agglomeration and yellowing, and has high transparency, high strength and excellent heat aging resistance.
Owner:CHENGDU LONGCHENG HIGH TECH MATERIAL

Anti-drunkenness composition and application thereof

PendingCN121313676ANervous disorderHydroxy compound active ingredientsSerum glutamate pyruvate transaminaseAlanine aminotransferase
The invention discloses an anti-drunkenness composition and application thereof. The invention provides an application of a composition in preparation of an anti-drunkenness product, the composition contains edible plasma powder, xylitol, fructo-oligosaccharide, microcrystalline cellulose, mogroside and magnesium stearate, and the edible plasma powder contains immune globulin IgG. The TZK provided by the invention has obvious regulation and improvement effects on sleep behaviors, serum indexes and gastrointestinal injury after acute drinking. The oxidative stress state after long-term large-dose chronic drinking is effectively adjusted, so that the oxidative stress injury index malondialdehyde (MDA) gradually returns to the normal level; according to the present invention, the activity of the liver injury markers such as alanine transaminase (ALT) and aspartate transaminase (AST) is reduced, the liver protection effect is provided, and the gastric mucosa structure repair is promoted by increasing the gastric mucosa prostaglandin content and reducing the local MDA level;
Owner:XIANGYANG WEIEN BIOTECHNOLOGY CO LTD

Agropyron mongolicum drought-resistant seedling-protecting type charcoal crusting coating and preparation method of coated seeds thereof

The invention discloses an agropyron mongolicum drought-resistant seedling-protecting type charcoal crusting coating and a preparation method of coated seeds thereof. The biochar crusting coating sequentially comprises three layers from inside to outside: a first layer: a nucleating stage layer; the second layer is an effective substance adding and increasing period layer; the third layer is a film forming period layer; in the second layer, bentonite, talcum powder, magnesium stearate and biochar are mixed according to the mass ratio of 10: 5: 5: (0.7-3.3) to prepare a mixture of bentonite, talcum powder, magnesium stearate and biochar. According to the method, the environment-friendly biochar is adopted to carry out shell treatment on the agropyron mongolicum seeds, the drought resisting and seedling keeping capacity of the agropyron mongolicum seedlings under drought is improved, successful planting of the agropyron mongolicum is facilitated, the seed consumption is reduced, the production cost is reduced, pasture production in arid and semi-arid regions in China is further promoted, and meanwhile ecological restoration of degraded grassland is effectively restored.
Owner:CHINA AGRI UNIV

A method for preparing a male health tablet for treating prostatitis

This invention relates to the field of pharmaceutical preparation technology, and particularly to a method for preparing a male enhancement tablet for treating prostatitis. The method optimizes the composition and ratio of auxiliary materials other than the raw medicinal materials. To prepare 2 million tablets of this product, only approximately 1.3 kg of silica, 1.3 kg of magnesium stearate, 90 kg of corn starch, 18 kg of microcrystalline cellulose, 600 kg of ethanol, and 15 kg of gastric-soluble film-coating premix are required. The oil extraction process has also been improved, with the water addition reduced from 6 times the amount of raw materials to 0.4-0.6 kg. The method also changed the process of extracting oil from the medicinal materials by dividing them into eight separate pots for oil extraction. This refined dispersion process greatly saved water consumption and improved the quality of the extracted oil. An additional step of stirring the alcohol precipitation solution for one hour was added to improve the quality of the supernatant. The volatile ether extract of the male health tablets produced by the method of this invention was measured, and the average value of volatile ether extract was found to be 0.53%, which is about 60.6% higher than the 0.33% of the original process, demonstrating significant technological progress.
Owner:SHANXI WANGLONG PHARM GRP CO LTD

High-strength wear-resistant thermoplastic polyurethane composite material and preparation method thereof

PendingCN121450085APolymer scienceAluminum Stearate
The invention belongs to the technical field of polyurethane materials, and particularly relates to a high-strength wear-resistant thermoplastic polyurethane composite material and a preparation method thereof. The high-strength wear-resistant thermoplastic polyurethane composite material provided by the invention is mainly prepared from the following raw materials in parts by mass: 85-92 parts of thermoplastic polyurethane, 5-8 parts of modified spherical calcium carbonate, 1-2.5 parts of aluminum stearate, 0.5-1 part of a surfactant and 0.5-1 part of a crosslinking aid. Through the combined action of the modified spherical calcium carbonate and the magnesium stearate, the shear fracture of a TPU molecular chain can be effectively inhibited, and synchronous improvement of abrasion reduction and mechanical properties is realized. Experiments prove that on the basis of low filler addition amount and low cost, the mechanical strength and wear resistance of the polyurethane composite material are effectively improved, meanwhile, the injection molding characteristic of the material is not affected, and the polyurethane composite material has wide application prospects in bulk TPU application scenarios.
Owner:JIANGSU NUODAO PIPELINE TECHNOLOGY CO LTD

A Tibetan bath composition complex medicament and a preparation method thereof

This invention discloses a Tibetan bath composition compound and its preparation method, relating to the field of daily chemical products technology. The Tibetan bath composition compound consists of a ternary complex of scutellaria baicalensis hydroxypropyl-β-cyclodextrin nanoshell powder, Bacillus subtilis, Tibetan medicine composition, starch, anhydrous citric acid, sodium bicarbonate, calcium citrate, crospovidone, and magnesium stearate. Bacillus subtilis is used to ferment the ternary complex of scutellaria baicalensis hydroxypropyl-β-cyclodextrin nanoshell powder to obtain a fermentation-modified porous carrier, which is then loaded with the Tibetan medicine composition to form a Tibetan medicine inclusion powder. This not only achieves efficient drug delivery through a triple mechanism of biomodification, metabolite synergy, and structural optimization, but also forms a quaternary system with Terminalia chebula. The effervescent effect also enhances the penetration of Tibetan medicine components, which is beneficial for better exerting the antibacterial and anti-inflammatory effects of active substances, and significantly improving fungal infections and eczema-related skin problems.
Owner:ZHEJIANG CHINESE MEDICAL UNIVERSITY

A zhi-shu yang-wei tablet for chronic gastritis and a dry compression tablet process of granules thereof

PendingCN122297623ABiotechnologySucrose
This invention discloses a Zhishu Yangwei tablet for chronic gastritis and its granule dry-compression tableting process, relating to the field of traditional Chinese medicine preparation technology. The Yangwei tablet is made from the following raw materials in parts by weight: Codonopsis pilosula 35-45 parts, stir-fried Atractylodes macrocephala 18-22 parts, Poria cocos 18-22 parts, Glycyrrhiza uralensis 8-12 parts, Amomum villosum 18-22 parts, Lindera strychnifolia 18-22 parts, Salvia miltiorrhiza 45-55 parts, roasted Aucklandia lappa 18-22 parts, Paeonia lactiflora 18-22 parts, stir-fried Citrus aurantium 18-22 parts, Magnolia officinalis 28-32 parts, Lilium brownii 35-45 parts, and stir-fried chicken gizzard lining 18- 22 parts, dried plum 45-55 parts, Coptis chinensis 8-12 parts, hawthorn 35-45 parts, magnesium stearate 5-7 parts, sucrose 28-32 parts; This invention uses low-temperature dynamic extraction technology to replace the traditional high-temperature decoction process, effectively reducing the decomposition loss of heat-sensitive active ingredients such as tanshinone IIA and ursolic acid, and improving the bioavailability of the drug. It also uses membrane concentration and spray drying technology to replace the traditional atmospheric pressure concentration and oven drying process, shortening the production cycle, reducing energy consumption, and avoiding the degradation of active ingredients caused by prolonged heating of materials.
Owner:SHIZHONG DISTRICT TRADITIONAL CHINESE MEDICINE HOSPITAL OF LESHAN CITY

Candesartan cilexetil capsule and preparation method thereof

PendingCN121987583Afix stability issuesAvoid the possibility of crystallizationOrganic active ingredientsPharmaceutical non-active ingredientsCelluloseCaplet Dosage Form
The invention provides a candesartan cilexetil capsule and a preparation method thereof, and the candesartan cilexetil capsule is characterized in that each capsule contains candesartan cilexetil, lactose, corn starch, hydroxypropyl cellulose, carboxymethyl cellulose calcium, polyethylene glycol 8000 and magnesium stearate. According to the candesartan cilexetil capsule provided by the invention, the problem of stability of candesartan cilexetil is solved, the possibility of crystal transformation of common tablets in a tabletting process is reduced, and the characteristic dissolution curve of a final product is similar to that of a reference preparation; the preparation method is simple in process route, the fluidized bed one-step granulation method enables the loss to be less, the product yield is higher, and the industrial mass production cost is reduced.
Owner:珠海润都制药股份有限公司

Moisture-proof anti-caking beta-aminoisobutyric acid and preparation method thereof

The invention provides moisture-proof and anti-caking beta-aminoisobutyric acid and a preparation method thereof. The moisture-proof and anti-caking beta-aminoisobutyric acid comprises the following components in percentage by weight: 80-98% of beta-aminoisobutyric acid; and 0.1-15% of one or more of ethyl cellulose, lactose, resistant dextrin, hydroxypropyl methylcellulose, povidone, sodium carboxymethyl cellulose, magnesium stearate, calcium hydrophosphate and aerosil.
Owner:NANJING NUTRABUILDING BIO TECH CO LTD

Sublingual tablet and application thereof in desensitization therapy drug

PendingUS20260027044A1Peptide/protein ingredientsAllergen ingredientsLow-substituted hydroxypropylcelluloseMagnesium stearate
A sublingual tablet and application thereof in desensitization therapy drug are provided. The sublingual tablet is a low-dose allergen sublingual tablet. The sublingual tablet includes freeze-dried powder of allergen protein, lactose, mannitol, low substituted hydroxypropyl cellulose, low moisture microcrystalline cellulose, and magnesium stearate. The freeze-drying process is adopted to obtain the freeze-dried powder of allergen protein, and the powder direct compression technology is adopted to obtain the sublingual tablet of allergen protein. The low-dose sublingual tablet has excellent properties, including appearance, hardness, tablet weight variation, disintegration time, taste, and uniformity of content, in particular has outstanding advantages in disintegration time, uniformity of content, stability, and preparation process, and has an industrial application prospect.
Owner:ZONHON BIOPHARMA INST

Traditional Chinese medicine preparation for treating pleural effusion and peritoneal effusion and preparation method thereof

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine preparation for treating pleural effusion and peritoneal effusion and a preparation method thereof.The traditional Chinese medicine preparation is prepared from, by weight, 10-50 parts of traditional Chinese medicine extract, 30-70 parts of filler, 5-20 parts of enteric coating material, 5-15 parts of HPMC, 0.5-2 parts of triethyl citrate and 0.25-1.5 parts of magnesium stearate; poria cocos, polyporus umbellatus, rhizoma alismatis, astragalus membranaceus, curcuma zedoary, cassia twig, oldenlandia diffusa, sculellaria barbata, semen coicis and traditional Chinese medicine extracts are used as cores, the stability of volatile drugs is improved through an inclusion technology, and the volatile drugs are entrapped in a pH intelligent response type enteric coating material composed of aromatic ring-containing vinyl monomers, ethyl acrylate, DMAEMA and MAA. The traditional Chinese medicine preparation has the synergistic effect of efficiently inducing diuresis, activating blood circulation and eliminating tumors and enteric-coated long-acting directional delivery, and is suitable for patients with pleural effusion and peritoneal effusion, especially malignant effusion.
Owner:GUOJINGTANG (BEIJING) MEDICAL TECHNOLOGY CO LTD

Preparation method and application of nano organic pigments with different crystal forms

PendingCN121975348AEnsure control accuracyhigh purityQuinacridonesInorganic saltsWeather resistance
The invention relates to the field of organic pigments, and discloses a preparation method and application of nano organic pigments with different crystal forms. The preparation method comprises the following steps: 1) dissolving an organic pigment crude product in a good solvent, and adding inorganic salt for activation; 2) dropwise adding a poor solvent at a gradient rate, adding a crystal form guiding agent, and inducing formation of a crystal nucleus; wherein the alpha crystal form directing agent is magnesium stearate; the beta crystal form directing agent is dibutyl phthalate; the gamma crystal form directing agent is polyethylene glycol; the initial gradient rate is 0.5-1 mL / min, and the gradient rate is increased by 0.2-0.3 mL / min every 8-12 min; 3) ultrasonic treatment; 4) cooling, and adding a surface modifier for surface modification; according to the preparation method, the nanometer organic pigment with the target crystal form can be accurately obtained through process regulation and control, the nanometer organic pigment is uniform in particle size distribution, good in dispersity, good in heat-resistant stability and high in color and luster strength, and the nanometer organic pigment has the advantages of being good in flocculation-resistant stability and weather resistance after a coating is formed.
Owner:HANGZHOU BAIHE CLARIANT PIGMENTS CO LTD +1

Preparation of a manganese additive for the production of aluminum alloys and method of adding same

ActiveCN117305644BAl powderAluminate
The application relates to the technical field of manganese additive, and discloses a preparation of a manganese element additive for producing an aluminum alloy and an adding method thereof; manganese element additives are pre-added at a feeding port of a smelting furnace, and aluminum liquid is added through the feeding port; the manganese element additives comprise manganese powder, a dissolving aid and a bonding agent; the dissolving aid is selected from one or more of aluminum powder or fluoroaluminate; the fluoroaluminate is potassium fluoroaluminate and / or sodium fluoroaluminate; and the bonding agent is selected from one or more of magnesium stearate or sodium stearate. The preparation of the manganese element additive for producing the aluminum alloy and the adding method thereof can solve the problems of low actual yield and instability of the manganese element additive and long smelting time in the adding process in the prior art, and provide a technical means with higher purity, more convenient production and better adding effect.
Owner:YUNNAN YONGXIN ALUMINUM

Preparation and application of curcumin combined compound lactic acid bacteria tablet capable of improving anti-stress performance of animals

The invention relates to the technical field of animal anti-stress nutrition regulation and control, in particular to a curcumin and compound lactic acid bacteria combined tablet preparation which comprises the following components in percentage by weight: 40-60% of curcumin, 2-3% of compound lactic acid bacteria powder, 30-60% of skim milk powder, 0.2-0.5% of magnesium stearate and 0.2-0.6% of talcum powder. Wherein the compound lactic acid bacteria powder is composed of lactobacillus acidophilus and pediococcus acidilactici according to the viable count ratio of 1: 2-2: 1, and the viable count concentration of the compound lactic acid bacteria powder is 2.5 * 10 < 10 >-7.5 * 10 < 10 > cfu / g. The curcumin is used as prebiotics, the compound lactic acid bacteria are used as probiotics, a proper amount of auxiliary materials are added, the curcumin and lactic acid bacteria compound tablet is prepared, on one hand, the purpose of slow release in rumen is achieved, on the other hand, through the synergistic effect of the curcumin and the compound probiotics, the in-vivo anti-oxidation and anti-stress effects are improved, and the intestinal health of animals can be improved.
Owner:YANBIAN UNIV

Three-ply base double-channel prefabricated waterproofing roll with hook-and-loop fastener

The present application relates to waterproofing membrane technical field, propose a kind of three base double-channel prefabricated bite lap waterproofing membrane with touch fastener, from bottom to top, in turn include anti-adhesive layer, first permeation reaction adhesive layer, first polymer film base layer, second permeation reaction adhesive layer, second polymer film base layer, third permeation reaction adhesive layer, third polymer film base layer, fourth permeation reaction adhesive layer, rough surface silk layer and hook face layer;The adhesive of first permeation reaction adhesive layer, second permeation reaction adhesive layer, third permeation reaction adhesive layer and fourth permeation reaction adhesive layer respectively independently includes following weight parts component raw materials: asphalt, softener, SBS, SIS, tackifier, rubber powder, filler, filler is composed of heavy calcium carbonate, magnesium stearate modified active calcium carbonate and hollow glass microsphere.By the above technical solution, the problem of poor fixing, low peel strength and heavy quality of waterproofing membrane in related art is solved.
Owner:HEBEI YUYANGZELI WATERPROOF MATERIAL