15results about How to "Disintegrates quickly" patented technology

This invention discloses a method for producing crop cultivation substrate using sugarcane filter mud and sugarcane pith as main raw materials, comprising the following steps: (1) dissolving and diluting 4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid in water to obtain a solution; (2) mixing sugarcane slurry, sugarcane pith, the 4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid solution, fermentation agent, and improver, adjusting the moisture content, and then composting and fermenting. The compost is turned over every few days and continuously composted and fermented for several days to obtain the crop cultivation substrate. The crop cultivation substrate produced by this invention is of excellent quality, allowing direct planting of plants without root burn. Therefore, this invention, using sugarcane filter mud and sugarcane pith as main raw materials to prepare and produce crop cultivation substrate, can effectively solve the problem of comprehensive utilization of sugarcane filter mud and improve product sales.

The utility model discloses an environmental simulation device for soft rock mass disintegration rate test, including the box for simulating environment, the box top is equipped with the box cover that can open, and the bottom surface of box cover is fixed with the sprinkling tray to the box, and the sprinkling tray is connected with the water source outside through the pipeline fixed on the box cover, and the rotatable sample stage of containing rock sample is equipped in the box, and the water wave manufacturing mechanism of simulating water wave impact rock mass is still provided in the box. The environmental simulation of the utility model is closer to the actual situation, and the comprehensiveness and accuracy of soft rock mass disintegration rate test are improved.

The invention relates to the field of health food, in particular to a preparation method of milk-derived exosome buccal sugar, which comprises the following steps: mixing milk-derived exosome with a skeleton agent and auxiliary materials to prepare a dispersion solution; and placing the dispersion solution in an environment of-30 DEG C for vacuumizing, and then performing freeze drying according to freeze-drying program setting to obtain the milk-derived exosome buccal sugar. Through the preparation method, the activity of mEV in the product can be maintained to the maximum extent; the use amount of the freeze-drying protective agent is reduced, the mEV biological activity can be maintained, the mEV can be quickly released in the oral cavity, the taste is obviously improved, and the onset time is obviously prolonged.

The invention relates to the field of composite soft plastic packaging, in particular to a dynamic self-repairing type high-toughness bio-based degradable film and a preparation method and application thereof. The film is composed of a lactic acid high polymer, a copolymer of butylene adipate and butylene terephthalate, a compatibilizer, a nucleating agent, a catalyst, an auxiliary agent and an antibacterial agent, the catalyst is formed by mixing a main catalyst and a co-catalyst, the main catalyst comprises any one of zinc acetylacetonate, ferric acetylacetonate, antimony trioxide and zinc oxide, and the co-catalyst comprises any one of zinc acetylacetonate, ferric acetylacetonate, antimony trioxide and zinc oxide. The cocatalyst is selected from any one of triethylamine, triphenylphosphine and aluminum acetylacetonate. The invention provides an effective scheme for solving the core contradiction that the strength, toughness, repairability and controllable degradability of a bio-based material are difficult to consider at the same time, is expected to replace traditional plastics in the fields of high-end environment-friendly packaging, intelligent agricultural mulching films and the like, and has great environmental benefits and industrialization prospects.

The utility model discloses a device of on -the -spot red sandstone quick determination disintegration coefficient, including test device main part, be equipped with the base on test device main part, install the soaking cylinder and drying cylinder on the base, the utility model through setting up soaking area and drying area, respectively to red sandstone sample carries out soaking and drying treatment, through the lifting rod and the rotating motor drive sample moves between drying cylinder and soaking cylinder, spares the manual operation of operator, through setting up multiple test area, simultaneously, the same condition carries out multiple group disintegration test, and tries to exclude accidental error, in the soaking process, through the magnetic capsule rotation, drive the clear water in the soaking area rotation, utilize the flow to accelerate the disintegration of red sandstone, and the flow speed is limited, not to produce bigger external force, seriously influence red sandstone disintegration rate, in the drying process, through the fan acceleration drying, and remove the loose particle on the sample surface when drying, after drying, through the fan acceleration sample cooling.

The application belongs to the technical field of pharmaceutical preparations, and particularly relates to a compound pharmaceutical preparation based on spray lactose and a preparation method thereof. The compound pharmaceutical preparation comprises the following components in parts by weight: active drug 10-15 parts, spray lactose 27-33 parts, mannitol 30-35 parts, modified microcrystalline cellulose 13-16 parts, disintegrating agent 3-5 parts, lubricant 1-2 parts, and flavoring agent 1-3 parts. The compound pharmaceutical preparation has the characteristics of high hardness, low friability, rapid disintegration, good content uniformity, excellent taste masking effect and good taste.

The invention discloses a dapoxetine hydrochloride tablet pharmaceutical composition and a preparation method thereof, and belongs to the technical field of pharmaceutical preparations. The composition comprises dapoxetine hydrochloride, sodium bicarbonate, a filler, a disintegrating agent and a lubricant. Aiming at the problems of low dissolution rate, poor stability, complex preparation process and the like of dapoxetine hydrochloride tablets in the prior art, sodium bicarbonate is introduced as a key auxiliary material, a raw material pretreatment process is optimized, a traditional adhesive is omitted, and the dissolution rate and the preparation stability are remarkably improved. The preparation method comprises the following steps: pre-drying the filling agent (microcrystalline cellulose) until the water content is less than or equal to 2.0%, sieving sodium bicarbonate with a sieve of more than 100 meshes, mixing the sodium bicarbonate with dapoxetine hydrochloride and the lubricant, directly tabletting, and then coating. The preparation method is simple in process, low in cost and suitable for industrial production, and the obtained tablet is high in dissolution rate and excellent in stability under the conditions of high temperature, high humidity and illumination.

Disclosed is a nicotine disintegrating tablet for rapidly relieving nicotine craving, the tablet comprising nicotine, a disintegrating agent and at least one sugar alcohol wherein the tablet comprises an amount of a dissolution modifier wherein the amount of the dissolution modifier does not exceed 2% by weight of the tablet.

The present application relates to the technical field of traditional Chinese medicine preparation, in particular to a Huangbai eight flavor tablet and a preparation process thereof. The Huangbai eight flavor tablet is a film-coated tablet, comprising a tablet core and a double-layer film coating. The tablet core is composed of Huangbai, Xiangmo, Zhizi, Gancao, Honghua, Baidu, Niudan powder and Huangbai enrichment and re-addition granules. The total mass fraction of the eight medicinal materials is 89.0-97.8 wt%. The Huangbai enrichment and re-addition granules are prepared by adsorbing Huangbai alkaloid enrichment solution on self-supporting porous adsorption granules. The double-layer film coating comprises a carboxymethyl cellulose sodium-glycerol inner layer and a hydroxypropyl methyl cellulose-glycerol outer layer. The present application realizes high-concentration alkaloid enrichment and uniform re-addition through self-supporting porous adsorption technology, solves the contradiction between high loading and formability, realizes moisture-proof barrier and rapid disintegration balance through the double-layer film coating structure, significantly improves the tablet formability, stability and bioavailability, and is suitable for industrialized production of heat-clearing and dampness-drying traditional Chinese medicine.

This invention belongs to the field of functional probiotic screening and application technology, specifically involving a novel strain of *Lactobacillus plantarum* (…). Lactiplantibacillus plantarum The *Lactobacillus plantarum* strain was deposited on January 15, 2026, at the China Center for Type Culture Collection (CCTCC), Wuhan University, Wuhan, China, with accession number CCTCC NO: M202026133. This strain exhibits strong antioxidant capacity, significant inhibitory and flocculating effects against hemolytic streptococci, and can significantly reduce the levels of pro-inflammatory cytokines IL-6 and IL-1β induced by hemolytic streptococci while increasing the level of the anti-inflammatory cytokine IL-22. It has no toxic effects on the body, good safety profile, and can be used to prevent colonic polyps and colon cancer caused by hemolytic streptococci, showing broad application prospects.

The application discloses a paper cup and coffee residue synergic utilization convertible seedling cup and a preparation method thereof, and belongs to the field of solid waste resource utilization. In view of the pain point of traditional paper cup recycling, the application innovatively constructs a whole life cycle function conversion mechanism of "drinks containing-transplanting ventilation-planting degradation". Through the synergy of a special double-effect barrier coating and an external force activation structure, perfect balance between drinks-level barrier and intelligent root guidance during the seedling period can be achieved with only a very low coating amount, which significantly improves resource utilization and reduces material consumption compared with traditional single-function solutions. In combination with a standardized coffee residue substrate, in-situ closed-loop utilization of store solid waste is realized. The scheme provides an efficient carbon reduction solution with ecological benefits and commercial value for the industry.

The invention belongs to the technical field of blasting, and particularly relates to a blasting oxygenation device and method adaptive to a plateau low-oxygen environment, the device aims at solving the problem that explosive blasting reaction is incomplete in the plateau hypoxia environment, the device comprises a charging bag placed in a blasting hole, an oxygenation device, a partition device and a sealing plug, the oxygenation device is provided with a shell and a liner bag, and the liner bag is provided with an opening. The inner container bag stores oxygen, the partition device is composed of an upper cover plate and an annular air bag, the oxygen increasing device and the partition device are arranged between every two vertically adjacent charging bags, the sealing plug is located at the top of the blast hole, and when the charging bags are detonated, generated shock waves can enable the inner container bag of the oxygen increasing device to be broken to release oxygen, and meanwhile the annular air bag of the partition device is pushed to expand to seal the hole wall. According to the device, oxygen release and sealing are triggered by means of explosion energy, oxygen is supplemented for a reaction area at the moment of explosion, oxygen is prevented from overflowing, and the plateau explosion effect can be improved.

The application provides a brexpiprazole oral film, a preparation method and application thereof. The brexpiprazole oral film comprises the following components: an active drug and a film-forming material, wherein the active drug is 7-[4-(4-benzo[B]thiophene-4-yl-1-piperazine) butoxy]-2(1H)-quinolinone as shown in formula I and / or a pharmaceutically acceptable salt thereof, the particle size D 90 ≤70 μm of the active drug; the film-forming material is one or more of hydroxypropyl methyl cellulose, polyvinyl alcohol and hydroxypropyl cellulose; and the brexpiprazole oral film does not contain dimethyl silicone oil. The brexpiprazole oral film of the application has a good dissolution rate, does not have a sand feeling after being dissolved in the oral cavity, has a uniform appearance, good flexibility, does not settle during the preparation of the film liquid, and has a uniform content.

The application discloses a hydroxypropyl starch-based composition, a preparation method and application thereof. The application discloses a preparation method of the composition, which comprises hydroxypropyl starch, polyvinyl alcohol, glycerol, sorbitol, carrageenan, potassium acetate, hydroxypropyl methyl cellulose, dimethicone and water. The composition is used for preparing a hard gelatin capsule shell, and the hard gelatin capsule shell has the advantages of smooth surface, good transparency, high forming rate, low friability, short disintegration time and high stability, and can provide an important reference for replacing traditional gelatin capsules. The preparation method is simple, and the cost is low. The capsule has good apparent properties and forming properties, and has remarkable effects in resisting friability, fast disintegration, storage stability and the like, and has great application prospects in medical preparations, food packaging materials, health product packaging and the like.

This invention discloses a bergamot effervescent tablet based on microencapsulation technology and its preparation method, relating to the field of solid beverage technology. The invention comprises, based on a total feed weight of 100 kg, the following components: bergamot extract; 3 kg; anhydrous citric acid; 18 kg; sodium bicarbonate; 15 kg; dextrin; 45 kg; gum arabic; 0.6 kg; tragacanth gum; 0.15 kg; taurine; 1.58 kg; zinc gluconate; 0.75 kg; zinc citrate; 0.25 kg; calcium gluconate; 0.25 kg; ascorbic acid C; 0.1 kg; ferrous gluconate; 0.11 kg; thiamine hydrochloride; 0.058 kg; riboflavin; 0.03 kg; pyridoxine hydrochloride; 0.02 kg; cyanocobalamin; 0.001 kg; folic acid; 0.001 kg; isomaltitol; 15 kg; sucralose; 0.1 kg. The advantages are: through systematic screening of key factors such as the inclusion of aromatic oil components in bergamot extract, the ratio of acid-base disintegrants, the ratio of flavoring agents and food fortifiers, the type of fillers, the preparation method of acid-base particles, and the tableting process parameters.