2721 results about "Tableting" patented technology

The invention discloses an oral solid preparation melogabalin besylate tablet containing an excellent stabilizer and a preparation method thereof. A tablet core contains but is not limited to melogabalin besylate, one or two or more filling agents, one or two or more disintegrating agents, one or two or more flow aids and various stabilizer compositions. According to the invention, the optimal stabilizer composition is selected through investigation, so that the growth of main degradation impurities and oxidation impurities is effectively controlled, the product stability is improved, and the tablets with stable quality are obtained. The product is rapidly dissolved out, the dissolution uniformity is good, the intermediate tabletting is smooth, the compressibility is good, and the prepared finished product is good in appearance, free of small holes and stable and controllable in quality.

The invention discloses a pharmaceutical composition containing melogabalin besylate and a preparation method of the pharmaceutical composition. Belongs to the technical field of pharmaceutical preparations. Comprising melogabalin besylate and pharmaceutically acceptable auxiliary materials, the pharmaceutically acceptable auxiliary materials comprise a filler, a disintegrating agent, an adhesive, an antioxidant and a lubricant, the antioxidant comprises vitamin E succinic acid polyethylene glycol ester, and the lubricant comprises vitamin E succinic acid polyethylene glycol ester. The melogabalin besylate as the active ingredient accounts for 2-15% by weight of the pharmaceutical composition, preferably 2-10% by weight of the pharmaceutical composition. According to the pharmaceutical composition, antioxidant particles are prepared by adopting a fluidized bed granulation process, raw material medicines, the antioxidant particles and other auxiliary materials are mixed, tableted and coated, an antioxidant comprises vitamin E succinic acid polyethylene glycol ester and tartaric acid, and the prepared tablet has good stability.

The invention discloses a melogabalin besylate pharmaceutical composition and a preparation method thereof. The invention provides a pharmaceutical composition. The pharmaceutical composition comprises melogabalin besylate, ascorbyl palmitate, a filling agent and a disintegrating agent. According to the pharmaceutical composition provided by the invention, only one antioxidant is added, the antioxidant effect is better than that of a commercial product TARLIGE, the stability of prepared tablets is better, the process production is simple, and the pharmaceutical composition is more suitable for mixing and tabletting the tablets.

The invention discloses an atorvaquone enteric-coated tablet, the preparation comprises atorvaquone, glyceryl behenate, teloxpol, a filler, an adhesive, a disintegrating agent and an enteric coating, and the particle size D90 of the atorvaquone is 30-50 [mu] m. The atorvaquone enteric-coated tablet disclosed by the invention is stable and continuous in release and high in bioavailability, can be positioned and released in intestinal tracts and reduce liver circulation, so that the occurrence of phenomena such as liver injury is reduced, the phenomena such as sticking and cracking are avoided in a tabletting process, the quality is qualified and stable, and the dissolution performance and the stability of the atorvaquone enteric-coated tablet are also ensured.

The invention belongs to the field of solid electrolytes, and relates to an argyrodite type solid electrolyte and a preparation method and application thereof, the molecular formula is Li < 5.5-x > P < 1-x > W < x > S < 4.5-3x > O < 3x > ClyBr < 1.5-y >, during preparation, raw materials are premixed according to a molar ratio, and ball milling is performed to obtain solid electrolyte powder; and tabletting the solid electrolyte powder to obtain an electrolyte sheet, and sintering to obtain the argyrodite type solid electrolyte. According to the multifunctional electrolyte disclosed by the invention, the ionic conductivity is improved, and meanwhile, the stability to air is relatively good.

The invention provides MAB-phase ceramic powder as well as a preparation method and application thereof, and belongs to the technical field of ceramic materials. Firstly, elementary substance M powder and boron powder serve as raw materials, and MB powder is prepared through ball milling treatment, tabletting, heat treatment and grinding; the simple substance M powder is selected from transition metal powder; the preparation method comprises the following steps: by taking MB powder and aluminum powder as raw materials, carrying out wet ball-milling treatment, compression molding, packaging and sintering treatment to prepare MAB-phase ceramic powder; the packaging is carried out by adopting potassium bromide powder. According to the invention, an MS3-fused salt shielding synthesis / sintering method is adopted, salt is used as a reaction medium and a salt bed, the exterior of a sample is packaged with salt, so that a synthetic product is prevented from being oxidized during high-temperature synthesis in the air, and the preparation method has the characteristics of rapidness, high efficiency, energy conservation, environmental protection, low cost and the like, and is simple, convenient and feasible in the aspect of promotion of large-scale production.

The invention discloses a bone health tablet candy rich in marine peptide calcium chelate and a preparation method thereof, and belongs to the technical field of polypeptide biologication.The calcium chelating peptide provided by the invention has an amino acid sequence as shown in SEQ ID No.1, the specific sequence is GETGPA (F21-1), and the calcium binding capacity is 4.72 + / -1.06 mu g / mg. The bone health tablet candy provided by the invention has relatively good calcium absorption promoting activity. A mouse experiment result shows that no adverse effect is caused to mouse growth, high bone transition caused by osteoporosis can be reversed, the bone biomechanical property of the osteoporosis mouse is improved, and then the effect of enhancing the bone mineral density is achieved.

The invention relates to the field of rubber sealing rings, and discloses a refrigerant-resistant HNBR sealing ring and a preparation method thereof. The refrigerant-resistant HNBR sealing ring is prepared from the following raw materials in parts by weight: 100-120 parts of HNBR, 45-55 parts of nano modified magnesium aluminum silicate, 40-50 parts of white carbon black, 10-20 parts of a plasticizer, 6-10 parts of a cross-linking agent, 5-8 parts of an active agent, 5-8 parts of a vulcanizing agent and 1-3 parts of an anti-aging agent, the preparation method comprises the following steps: mixing the raw materials, tabletting and cutting; and carrying out mold pressing vulcanization forming and punching. The preparation process is simple, and the prepared HNBR sealing ring is applied to a new energy automobile air conditioner, is suitable for a cold and heat cycle environment, has relatively good flexibility, and can keep relatively good aging resistance and sealing performance when being in contact with a refrigerant for a long time.

The invention belongs to the field of synthesis of inorganic non-metallic materials, and particularly relates to an equimolar-ratio seven-element high-entropy oxide and a preparation process thereof. The preparation process comprises the following steps: putting seven oxide powder Al2O3, Y2O3, TiO2, ZrO2, NiO, CuO and CeO2 into a ball milling tank according to a molar ratio of 1: 1: 2: 2: 2: 2: 2: 2, adding absolute ethyl alcohol and zirconium oxide grinding balls, performing ball milling in a ball mill, and fully drying and sieving after ball milling to obtain mixed powder; carrying out tabletting treatment on the mixed powder to obtain a to-be-sintered green body; and putting the to-be-sintered green body into an alumina crucible, and putting the alumina crucible into a microwave oven for microwave sintering. According to the method, the equimolar-ratio seven-element high-entropy oxide (AlYTiZrNiCuCe) Ox with good solid solution is obtained, the crystallinity and element uniformity of the seven-element high-entropy oxide are improved, all the raw materials react completely, meanwhile, the process efficiency is high, and energy consumption is low.

The invention discloses a preparation method of perindopril amlodipine tablets, and belongs to the field of pharmacy. The perindopril amlodipine tablet is prepared from the following raw material medicines: arginine perindopril and amlodipine besylate and auxiliary materials: lactose, microcrystalline cellulose, hydrophobic colloidal silicon dioxide and magnesium stearate. The preparation method of the perindopril amlodipine tablet comprises the following steps: weighing according to the prescription amount, crushing and sieving the raw materials for pretreatment, sieving the whole particles of the auxiliary materials for pretreatment, premixing, feeding and total mixing, tabletting and the like. The prepared perindopril amlodipine tablet is relatively good in quality, high in stability and relatively few in waste products.

The invention discloses an abesilil raw material medicine, a composition, a tablet and a preparation method thereof. The particle size distribution of the abesilil raw material medicine is as follows: D10 is more than or equal to 20 microns, D90 is more than or equal to 60 microns and less than or equal to 300 microns, and the span (D90-D10) / D50 is less than or equal to 2.5. According to the present invention, the large raw material particle size within a certain range is provided, the dissolution rate and the dissolution amount of the abelsilil tablet in the pH 6.8 medium can be easily improved, the sticking phenomenon during the tabletting process can be solved, the production process is simple, the production period is short, the production cost is low, the mixing and the tabletting are smooth, and the dissolution end point is high.

The invention discloses a potassium ferrate composite environmental remediation material as well as a preparation method and application thereof. The material comprises the following components in percentage by weight: 40-70% of potassium ferrate; 20-50% of a porous carrier; and 5-10% of a stabilizer. The preparation method comprises the following steps: S1, potassium ferrate synthesis: synthesizing potassium ferrate under the action of an auxiliary catalyst by adopting a sodium hypochlorite oxidation method; s2, modifying a porous carrier: activating the porous carrier with acid, soaking the porous carrier in a stabilizer solution, and drying for later use; and S3, composite loading: mixing the potassium ferrate powder and the porous carrier in proportion, then adding a binder, carrying out ball milling, then carrying out tabletting molding, and then carrying out calcination in an inert atmosphere to obtain porous composite particles, namely the environmental remediation material. The composite structure delays decomposition of potassium ferrate, and the validity period of the material is prolonged to 6 months or above. The porous carrier provides adsorption sites and cooperates with the oxidation-adsorption effect to improve the pollutant removal rate. The calcining process enhances the mechanical strength of the material, and is suitable for flowing water or deep soil injection.

The invention discloses a preparation method of sturgeon roe peptide freeze-dried powder with an anti-aging effect. The preparation method specifically comprises the following steps: (1) unfreezing sturgeon roes, adding water, uniformly stirring, grinding and crushing, and adjusting the pH value; (2) heating and naturally cooling; (3) adding alkaline protease, uniformly stirring, carrying out enzymolysis, and adding starch sodium octenylsuccinate and vitamin E powder; (4) carrying out enzyme inactivation, naturally cooling, and adjusting the pH value; (5) carrying out rough filtration and centrifugal treatment, taking supernate, adsorbing, filtering and taking filtrate; and (6) carrying out plate frame filtration, taking filtrate, carrying out vacuum freeze drying, screening and packaging, thereby obtaining the product. The preparation method disclosed by the invention has the advantages of simplicity and convenience in operation, low cost, high embedding yield and the like, and has important significance in improving the stability and biological activity of the sturgeon roe peptide. Moreover, the sturgeon roe peptide freeze-dried powder has an anti-aging effect, and can be widely applied to oral liquid, solid beverages, tablet candies and the like in common foods.

The invention discloses a sampling inspection device and a use method thereof, and belongs to the technical field of material detection, the sampling inspection device comprises a rack, a tabletting mold, a mold shifting device, a sampling device, a tabletting device, a detection device and an electric control device; the sampling device is connected with an unloading conveying pipe of the powder tank truck; the tabletting device is used for tabletting the powder sample in the tabletting mold; the mold shifting device is arranged on the rack to drive the tabletting mold to move among the positions of the sampling device, the tabletting device and the detection device; the detection device is used for detecting a tabletting sample in the tabletting mold; the electric control device is electrically connected with the sampling device, the tabletting device, the mold shifting device and the detection device; and the cooperative work of each working procedure is realized.

The invention relates to the technical field of medicines, in particular to a compound amlodipine atorvastatin calcium tablet and a production mixing device. The compound amlodipine atorvastatin calcium tablet is a core-coated tablet and comprises an inner-layer tablet core containing atorvastatin calcium and an outer-layer tablet layer containing amlodipine besylate, the inner-layer tablet core further comprises meglumine and sodium lauryl sulfate, the mass ratio of meglumine to sodium lauryl sulfate is (0.5-5): 1, the mass ratio of meglumine to sodium lauryl sulfate is (0.5-5): 1, and the mass ratio of meglumine to sodium lauryl sulfate is (0.5-5): 1. And the mass of the meglumine accounts for 1-3% of the total mass of the inner-layer tablet core. The amlodipine and atorvastatin calcium are prepared into the coated tablet, so that two active ingredients in the same tablet are effectively isolated, and the compatibility of the atorvastatin calcium and the amlodipine besylate is remarkably improved; meanwhile, the inner layer and the outer layer of the core-coated sheet are separately granulated before tabletting, so that the problem that the mixing uniformity of total mixed particles is relatively poor when conventional tablets are prepared is effectively solved.

The invention discloses a sealing cover mounting structure adopting a pressure self-adaptive sealing structure, which is based on a conventional sealing cover structure, takes a rubber ring as a basic structure, optimizes and adds a co-action component, and particularly takes the internal pressure of a container as a power source for cooperatively changing the up-down moving process of a movable ring, so that the pressure self-adaptive sealing structure is formed. The rubber ring is arranged on the inner wall of the container, the lower pressing piece, the upper pressing piece and the multiple externally-expanded jacking blocks are matched to reinforce the rubber ring again, the contact force between the rubber ring and the inner wall of the container is improved, and therefore the sealing effect of the whole structure is improved, and the air bag with the corresponding effect is additionally arranged between the upper pressing piece and the lower pressing piece; on the other hand, the pressure change in the container can be matched in an active air supply mode, and the purpose is to further interfere with the movement mode of the upper pressing piece and the lower pressing piece in cooperation with the pressure change in the container, so that the sealing capacity of the whole sealing structure is in a relatively stable state.

The application discloses a bone health tablet candy rich in marine peptide calcium chelate and a preparation method thereof, and belongs to the technical field of polypeptides, wherein the calcium chelate peptide provided by the application has an amino acid sequence as shown in SEQ ID No.1, and the specific sequence is GETGPA (F21-1), and the calcium binding capacity of the calcium chelate peptide is 4.72±1.06 μg / mg. The bone health tablet candy provided by the application has good calcium absorption promoting activity. The results of a mouse experiment show that the bone health tablet candy does not cause adverse effects on the growth of mice, can reverse high bone conversion caused by osteoporosis, improves the bone biomechanical properties of osteoporotic mice, and thus achieves the effect of enhancing bone density.

The invention relates to the technical field of food processing, in particular to a food processing crusher which comprises a conveying cylinder with the right end inclining downwards, a feeding cylinder is fixedly installed at the left end of the upper side of the conveying cylinder, a discharging port is formed in the right end of the lower side of the conveying cylinder, a shaking-up device is installed in the conveying cylinder, and a driving device is further installed in the conveying cylinder. An impact device and a grinding device are sequentially mounted on the driving device from left to right, and the impact device is used for impacting and crushing candy raw materials; the crushing device is used for crushing candy raw materials, and the candy raw materials are crushed in a manner of impact crushing and grinding crushing of the candy raw materials, so that the hard blocky candy raw materials can be thoroughly crushed, and the processed candy raw materials are uniform in particle size; and meanwhile, large blocky or granular candy raw materials in the candy raw materials can be uniformly distributed, so that the processing efficiency of the candy raw materials is improved.

The invention relates to an alprazolam oral solid composition and a preparation method thereof. In one aspect, the invention relates to an alprazolam tablet, which is prepared by preparing premixed particles containing alprazolam in advance and then preparing the tablet by a wet granulation and tabletting method. The premixed particles comprise alprazolam, microcrystalline cellulose and the like, and the tablet further comprises microcrystalline cellulose, corn starch, silicon dioxide, magnesium stearate and the like. The alprazolam tablet disclosed by the invention can be used as a medicine for resisting anxiety, tension, depression, excitation, hypnosis, panic, relieving acute alcohol withdrawal symptoms and resisting drug-induced intractable hiccup, and has certain excellent performance.

The invention discloses a brassica rapa alkali extract with anti-hypoxia activity as well as a preparation method and application of the brassica rapa alkali extract. The method comprises the following steps: by taking brassica rapa tuberous roots as a raw material, rinsing, slicing, drying, crushing, extracting with a food-grade calcium oxide alkaline solution, carrying out centrifugal separation to obtain supernate, and carrying out spray drying on the supernate to obtain the brassica rapa alkali extract. The method is easy to operate, low in cost and high in extraction rate, starch and crude fiber auxiliary components in the brassica rapa tubers can be removed to a large extent, the most important components with health-care functions of brassica rapa are reserved, and the biological activity of nutritional components of brassica rapa is kept. Results of evaluation and biochemical index determination of a normal-pressure closed experiment and a sodium nitrite poisoning experiment show that the brassica rapa alkali extract can remarkably prolong the survival time of mice, improve the activity of superoxide dismutase in the mice and reduce the content of malondialdehyde, and shows a relatively good hypoxia tolerance effect. The alkali extract can be used for developing hypoxia-resistant functional foods such as tabletted candies and biscuits, and has a wide application prospect.

The invention relates to the technical field of preparation of marine bioactive substances and functional foods, in particular to oyster peptide and application thereof in preparation of products for improving alcoholic liver injury. According to the invention, oyster peptide raw materials rich in natural taurine are adopted, scientific formula design and natural plant alcohol effect dispelling and liver protecting components are adopted, and adverse reactions after drinking, such as hangover, fatigue and alcoholic liver injury, are effectively relieved; according to the oyster peptide tabletted candy formula with the functions of dispelling the effects of alcohol and protecting the liver, provided by the invention, functional components all meet design requirements through detection.

The invention provides a preparation method of a trazodone hydrochloride sustained release tablet, and belongs to the technical field of medicine processing. The preparation method comprises the following steps: (1) mixing a trazodone hydrochloride raw material medicine, cane sugar, povidone and carnauba wax to obtain a mixture; (2) preparing the mixture into molten particles by adopting a hot-melt extrusion technology; and (3) cooling and sieving the molten particles, adding magnesium stearate, uniformly mixing, and tabletting to obtain the trazodone hydrochloride sustained-release tablet. The trazodone hydrochloride sustained release tablet comprises the following components in percentage by mass: 45%-55% of trazodone hydrochloride raw material medicine, 15%-35% of cane sugar, 5%-15% of povidone, 5%-15% of carnauba wax and 1%-5% of magnesium stearate. According to the invention, a hot melt extrusion technology is adopted, so that the raw materials can be highly dispersed within a short heating time, the loss of the raw materials is avoided, the production cost is reduced, and commercialized production is facilitated.

The invention relates to the technical field of medical care, and particularly discloses a preparation method and application of sea cucumber peptide. The preparation method of the sea cucumber peptide provided by the invention comprises the following steps: heating sea cucumber primary pulp for denaturation, and then adding compound protease for enzymolysis treatment to obtain sea cucumber enzymatic hydrolysate; the addition amount of the compound protease is 0.1-0.15 mg / mL, and the compound protease is prepared from papain, ficin and trypsin according to the weight ratio of 1: (0.5-1.5): (2-3); adding activated carbon and diatomite into the sea cucumber enzymatic hydrolysate, and performing enzyme deactivation, filtration and concentration treatment to obtain sea cucumber peptide; the invention also provides application of the sea cucumber peptide obtained by the preparation method in medicines and foods. According to the preparation method of the sea cucumber peptide, the sea cucumber peptide with small molecular weight and good uniformity can be obtained, and the prepared sea cucumber peptide tablet candy has the effects of relieving physical fatigue, resisting aging, resisting oxidation and the like.

The invention relates to the technical field of medicines, in particular to magnesium oxide particles, a preparation method thereof and magnesium oxide tablets. The magnesium oxide particles comprise the following components in percentage by mass: 50%-85% of magnesium oxide, 3%-10% of protein hydrophilic colloid, 3%-10% of a cross-linking agent and the balance of a filling agent, wherein the cross-linking agent comprises cellulose and / or cellulose derivatives. The preparation method comprises the following steps: S1, adding the protein hydrophilic colloid into water, stirring until the protein hydrophilic colloid is swelled, and heating or adjusting pH to induce hydrogel as slurry; s2, weighing magnesium oxide, a cross-linking agent and a filling agent according to a formula proportion, stirring and mixing, and then adding the slurry under stirring and shearing conditions for granulation and coating; and S3, granulating, drying and sieving the material to obtain the product. When the magnesium oxide particles are used for preparing tablets, the tablets can be effectively prevented from cracking, and meanwhile, the problem of black edges in the tabletting process can be solved.

The invention discloses a ceramic material for a high-temperature water-oxygen environment and a preparation method of the ceramic material, and belongs to the technical field of environmental barrier coatings. According to the preparation method disclosed by the invention, the Al2O3 modified Yb2Si2O7 powder is prepared into the tablet with a certain size and shape by a dry pressing method, and finally the tablet is sintered into the ceramic material by a pressureless sintering method in the atmosphere, so that the obtained ceramic material for the high-temperature water-oxygen environment can meet the application in the high-temperature water-oxygen environment of 1500 DEG C, has excellent high-temperature environment use performance, and is suitable for being used in the high-temperature water-oxygen environment. And the requirement of a thermal protection component on a C / C composite material high-temperature environment barrier coating is met.

The invention provides anhydrous magnesium chloride and a preparation method thereof, and the preparation method comprises the following steps: mixing MgCl2. NH2O and ammonium chloride, carrying out ball milling, tabletting and granulating the mixed material, and heating and sintering the obtained flaky particles to obtain the anhydrous magnesium chloride, wherein n is an integer, and 0 < n < = 6. The water-containing magnesium chloride and the ammonium chloride can form an alternately coated sandwich structure through the pretreatment modes of ball milling and tabletting granulation, so that hydrogen chloride gas and ammonia gas generated during heating decomposition are diffused from the inside of the flaky particles to the outside, and meanwhile, the water-containing magnesium chloride in the particles can be fully exposed in a hydrogen chloride atmosphere; mgO generated in the sintering process is reduced; according to the tabletting and granulating method, large pores can exist among the flaky particles, generated water molecules can be taken away from a heating system from the pores existing among the flaky particles along with gas circulation in the heating and sintering process, and dehydration is better achieved. Meanwhile, the method is more beneficial to model selection of dehydration equipment.

The utility model relates to a candy tabletting device for candy production, which comprises a shell, a mould is arranged in the shell, a mould hole penetrating through the upper surface and the lower surface of the mould is arranged on the mould, an upper telescopic device is arranged above the mould, the telescopic end of the upper telescopic device is vertically downward, and the lower telescopic device is arranged above the mould. A telescopic end is arranged on the lower portion of the die, an upper mounting plate is arranged at the telescopic end, an upper pressing piece matched with a die hole is arranged on the lower surface of the upper mounting plate, a lower telescopic device is arranged below the die, the telescopic end of the lower telescopic device is vertically upward, and a lower mounting plate is arranged at the telescopic end. The upper surface of the lower mounting plate is provided with a lower pressing piece matched with the mold hole; after tabletting candies are ejected out of a mold hole through the lower telescopic device, the side telescopic device drives the material pushing plate to scrape the tabletting candies from the surface of a mold, and meanwhile, the powder pump conveys raw materials into the mold hole through the material pushing plate, so that feeding and discharging are automatically and continuously carried out, and the tabletting efficiency of the candies is greatly improved.

The present invention relates to a 2-(4-methylthiazol-5-yl)ethyl nitrate hydrochloride tablet, comprising 2-(4-methylthiazol-5-yl)ethyl nitrate hydrochloride, glyceryl monostearate and other oral solid excipients. The present invention not only solves the problems of sticking and corrosion to equipment during tableting by using glyceryl monostearate in the tablet, but also improves the stability of the product. The production process is simple and easy to control, and is suitable for mass production.

The invention provides a fat-reducing and weight-reducing food composition, a tablet candy as well as a preparation method and application of the tablet candy, and belongs to the technical field of foods. The fat-reducing and weight-reducing food composition provided by the invention is prepared from the following raw materials in parts by weight: 4 to 8 parts of epigallocatechin gallate, 8 to 16 parts of raw coffee powder, 2 to 6 parts of ginseng peptide powder, 22 to 38 parts of fish oil microcapsule powder, 39.5 to 44.5 parts of a sweetening agent, 3 to 7 parts of a filling agent and 0.5 to 1.5 parts of a lubricating agent. Wherein the sweetening agent is sorbitol, the filling agent is microcrystalline cellulose, and the lubricating agent is magnesium stearate. The food composition can be used for preparing tabletted candies which are good in fat-reducing and weight-reducing effects, good in stability and low in friability.

The invention discloses a method for extracting active ingredients of traditional Chinese medicinal materials based on ultralow-temperature crushing and deep eutectic solvent synergy, a tableted candy for dispelling effects of alcohol and protecting liver and a preparation method of the tableted candy. The ultralow-temperature crushing and deep eutectic solvent synergy extraction technology is combined, and the active ingredients of the traditional Chinese medicinal materials with homology of medicine and food are extracted at low temperature; the method comprises the following steps: firstly, quickly freezing a raw material by using liquid nitrogen and mechanically crushing the raw material to improve the cell wall breaking rate, then stirring and mixing a deep eutectic solvent based on choline chloride and glycerol with water to reduce the viscosity of the solvent for extraction, and carrying out ultrasonic extraction, filtration, macroporous adsorption resin recovery and other steps to obtain a high-purity extract. According to the preparation method, the extraction rate of active substances in the traditional Chinese medicinal materials is increased, and extracts of multiple medicinal and edible Chinese herbal medicines such as lucid ganoderma, radix puerariae, hawthorn and olive are compounded into the tablet candy, so that liver injury caused by alcohol is effectively improved, and side effects caused by long-term administration of medicines can be effectively avoided.