893 results about "Tableting" patented technology

The application discloses a bone health tablet candy rich in marine peptide calcium chelate and a preparation method thereof, and belongs to the technical field of polypeptides, wherein the calcium chelate peptide provided by the application has an amino acid sequence as shown in SEQ ID No.1, and the specific sequence is GETGPA (F21-1), and the calcium binding capacity of the calcium chelate peptide is 4.72±1.06 μg / mg. The bone health tablet candy provided by the application has good calcium absorption promoting activity. The results of a mouse experiment show that the bone health tablet candy does not cause adverse effects on the growth of mice, can reverse high bone conversion caused by osteoporosis, improves the bone biomechanical properties of osteoporotic mice, and thus achieves the effect of enhancing bone density.

The invention relates to the technical field of preparation of marine bioactive substances and functional foods, in particular to oyster peptide and application thereof in preparation of products for improving alcoholic liver injury. According to the invention, oyster peptide raw materials rich in natural taurine are adopted, scientific formula design and natural plant alcohol effect dispelling and liver protecting components are adopted, and adverse reactions after drinking, such as hangover, fatigue and alcoholic liver injury, are effectively relieved; according to the oyster peptide tabletted candy formula with the functions of dispelling the effects of alcohol and protecting the liver, provided by the invention, functional components all meet design requirements through detection.

The invention relates to a doxepin hydrochloride tablet. The doxepin hydrochloride tablet is prepared from doxepin hydrochloride, polyethylene glycol 6000, a filling agent, a disintegrating agent, a flow aid and a lubricating agent. The preparation method comprises the following steps: heating and melting polyethylene glycol 6000, adding a doxepin hydrochloride raw material according to a prescription proportion, and uniformly stirring and mixing; and after complete melting, rapidly cooling and solidifying to form a solid dispersion. And after curing, drying in a drying oven, crushing and sieving. And uniformly mixing the crushed particles with the filler and the lubricant, and directly tabletting. The doxepin hydrochloride has high hygroscopicity, is unstable to damp and heat and easily generates a large amount of impurities under strong oxidation conditions, the doxepin hydrochloride is firstly prepared into a solid dispersion and then is directly compressed, so that the medicine is highly dispersed in a carrier material in the states of molecules, colloids, amorphous forms, microcrystals and the like, and the effect of wrapping the medicine is achieved by controlling the ratio of the medicine to the carrier. Direct contact between the medicine and air is avoided, so that the problems of hygroscopicity and instability of the medicine are solved, and the product stability is improved.

The utility model discloses a tablet pressing device for lercanidipine hydrochloride tablet production. The tablet pressing device comprises a rack; the working table is connected to the machine frame, and a template is arranged on the working table; the upper die set is connected to the upper portion of the workbench; the upper die set is connected to the lower portion of the workbench; and the material pushing assembly is connected to the working table. By controlling an electric telescopic rod to work, a loading frame can be driven to move, a forming groove is filled with medicine powder in the loading frame, the loading frame is returned, then an upper die set is controlled to work, the medicine powder in the forming groove is pressed into tablets, a lower die set works to eject extruded tablets out, the electric telescopic rod is controlled to work, and the loading frame and a pushing plate are driven to move. And tablets can be automatically pushed into the material collecting assembly through the material pushing plate to be collected, meanwhile, medicine powder is automatically fed in the material loading frame, the automation degree is high, and the working efficiency is improved.

The invention discloses a melatonin rapidly disintegrating oral tablet and a preparation method thereof, and the melatonin rapidly disintegrating oral tablet is prepared from the following raw materials in parts by weight: 40 to 55 parts of mannitol, 3 to 6 parts of cross-linked povidone, 0.5 to 2.0 parts of povidone, 2 to 6 parts of melatonin, 30 to 45 parts of filler and 0.3 to 1.5 parts of lubricant. Wherein the mannitol is beta-crystal form mannitol. According to the invention, mannitol of a limited type is matched with raw materials such as polyvinylpolypyrrolidone, and meanwhile, a specific mixing and tabletting process is adopted, so that the tablet can be rapidly disintegrated in an oral cavity while the hardness of the tablet is maintained, the bioavailability is high, and the requirements of the health food field on taking convenience, effectiveness and industrial production can be met.

The invention provides a method for measuring gamma-aminobutyric acid in tableted candies, which comprises the following steps: measuring gamma-aminobutyric acid in tableted candies by using HPLC-ELSD (High Performance Liquid Chromatography-Evaporative Light Scattering Detector) according to a volume ratio of acetonitrile to water of (50-70): (30-50) as a mobile phase; a chromatographic column is an amino column; a detector is ELSD, the temperature of a drift tube is 80-85 DEG C, and carrier gas is air. The detection method disclosed by the invention is strong in specificity, high in accuracy, strong in stability, good in repeatability and high in sensitivity, and compared with an existing derivation method, the method disclosed by the invention is simple, green and efficient, and can be used for effectively detecting the content of gamma-aminobutyric acid in the tabletted candies.

The application provides a method for preparing arosa polypeptide through microbial fermentation and application, which comprises the following steps: step one: taking arosa pomace as raw material, uniformly mixing a plurality of microbial fermentation liquor and arosa pomace, compacting and sealing the mixture in a light-proof sealed bag, fermenting at a temperature of 36 DEG C for 20 days, and obtaining arosa pomace active fermentation liquor; step two: using a high-speed refrigerated centrifuge to perform solid-liquid separation on the arosa pomace active fermentation liquor, and obtaining solid fermentation arosa pomace and fermentation supernatant; step three: using an alkali dissolution and acid precipitation method to extract arosa pomace protein from the solid fermentation arosa pomace; and step four: performing enzymolysis on the arosa pomace protein, and obtaining active peptide. The preparation method of the technical scheme improves the extraction rate of arosa polypeptide and the quality of protein, and provides a formula of arosa polypeptide in tablet candies and oral liquid.

The application discloses a salbutamol sulfate sustained-release tablet and a preparation process thereof. The preparation process comprises the following steps: drug micronization treatment, drug and ion exchange resin compounding, granulation with hydrophilic gel matrix material, gradient temperature control drying, total mixing after whole granulation, tabletting, double controlled-release coating, ladder solidification treatment and screening and packaging. Through the synergistic sustained-release effect of the ion exchange resin and the hydrophilic gel matrix material, the double controlled-release coating and the ladder solidification process, the application effectively inhibits drug burst release, realizes smooth and long-lasting release, reduces impurity content, and improves product stability and batch reproducibility. The obtained sustained-release tablet releases 20%-40% in 2 hours and 80% or more in 8 hours in a pH 6.8 phosphate buffer, and the quality is controllable, so the sustained-release tablet is suitable for industrial production.

The application discloses a kind of acanthopanax acid polysaccharides with intestinal protection function and its preparation method and application, belong to the field of functional food and biotechnology.The acanthopanax acid polysaccharide is by water extraction alcohol precipitation, after impurity removal, through DEAE-52 anion exchange column elution and collection 0.2 mol / L NaCl elution peak, and the uniform component obtained by Sephadex G-100 gel column chromatography purification.Its uronic acid content is 30%-40%, weight average relative molecular weight is 50-100kDa, mainly by glucose, galactose, galacturonic acid and arabinose, infrared spectrum has carboxyl characteristic absorption peak at 1736 cm-1 and 1615 cm-1.Experiments prove that the acanthopanax acid polysaccharide has antioxidant activity and hypoglycemic activity.The acid polysaccharide has protective effect on LPS-induced Caco-2 cell damage, can effectively reduce the secretion of pro-inflammatory factors TNF-α, IL-1β, IL-6, and improve the level of anti-inflammatory factor IL-10.The acanthopanax acid polysaccharide can be prepared into oral liquid, tablet candy, solid beverage and other functional food forms.

A control method for controlling the operating state of a rotary press (1) for forming tablets (100), wherein the rotary press (1) is a rotary compression turret (2), and includes a die table (3) on which a plurality of dies (4) are provided along the circumferential portion of the rotary compression turret (2), a plurality of lower punches (6) and a plurality of corresponding upper punches (5) associated in pairs with each die (4), the lower punches (6) and the upper punches (5) each having a substantially cylindrical body with contact ends into which a lower compression roller (12) and an upper compression roller (11) respectively abut, and a supply station (7), the control method for controlling the operating pressure of the lower compression roller (12) and the upper compression roller (11) The system comprises a control system (20) for controlling the operation, and includes a detection step in which the supply of powder (50) to the die (4) is blocked during the detection step so that there is at least one empty die (4a), the lower punch (6) and / or upper punch (5) are moved toward the at least one empty die (4a) by the respective lower and / or upper compression means, and a pressure resistance value is measured by the detection means (14) as the value of the pressure applied by the respective lower and / or upper compression means to the corresponding lower punch (6) and / or upper punch (5) as they are moved inside the at least one empty die (4a); and an evaluation step in which the pressure resistance value is processed by the control system (20) to generate a signal relating to the punch operation state.

The utility model relates to the technical field of tablet presses, and discloses a rotary tablet press which comprises a tablet press body, a supporting plate and a pressing piece, the supporting plate is arranged on the inner side of the tablet press body, a transmission mechanism is arranged in the tablet press body, and a scraper mechanism is arranged on the outer side of the supporting plate; the transmission mechanism comprises fixing plates, a first driving motor, a speed reducer, a connecting rod, a gear, a connecting ring and a fixing ring, the fixing plates are welded to the inner side of the tablet press body, the first driving motor is installed at the bottoms of the fixing plates, the speed reducer is installed at the tops of the fixing plates, and one end of the connecting rod is fixedly connected to the output end of the first driving motor; a rod piece of the first driving motor is connected with the input end of the speed reducer. According to the rotary tablet press, through cooperation of the gear, the connecting ring and the fixing ring, the tablet press body can stably rotate, so that the tablet press body does not easily incline when used for pressing dimness eliminating tablets, tablet pressing of the tablet press body is more accurate, and the stability of the tablet press body is improved.

The application belongs to the field of SOD preparation, and discloses a preparation method and device of SOD resistant to pepsin degradation, which comprises the following steps: S1 powder preparation: dissolving SOD fermentation pure liquid in a buffer solution with pH of 5.2-7.8, adding protective agent and tea yellow in sequence, stirring, filtering, and placing in a freeze dryer to prepare freeze-dried powder; S2 drying; S3 tabletting; S4, coating liquid preparation: dissolving wheat gliadin and soybean protein in a mixed solution prepared from water and ethanol with a volume ratio of 1:1, wherein the mass ratio of the wheat gliadin and the soybean protein is 0.5-1:1, adding glycerol, stirring for 20 min by using a magnetic stirrer, and ultrasonicating for 40 s; S5, coating: placing the tablets in a coating machine, setting air inlet volume, air inlet temperature, pan rotating speed, atomization rate, fan face pressure, and mortar flow, until the coating weight increases to 3%-10% in mass fraction and the coating thickness is 20-50 μm, and then drying and cooling. The prepared SOD is not easy to be photolyzed and can resist gastric acid degradation to ensure the complete activity of the SOD.

The invention relates to the technical field of traditional Chinese medicine tablet production, in particular to a production process and device of traditional Chinese medicine component tablets for treating cerebral arterial thrombosis, and the process comprises the following steps: squeezing celery and pumpkin vines in a juice squeezer, and sequentially filtering, deoxidizing and vacuum freeze-drying to obtain fine powder for later use; soaking salvia miltiorrhiza, pseudo-ginseng, ginkgo leaves, astragalus membranaceus and liquorice in a container, boiling, and mixing the two extracting solutions for later use; the preparation method comprises the following steps: putting naffide and betahistine into a container, adding distilled water, and uniformly stirring to obtain a solution for later use; and mixing the obtained fine powder, the filtrate and the solution, adding distilled water, then carrying out spray granulation, then carrying out tabletting forming, then carrying out drying again, and carrying out sealed packaging. The production device comprises a granulating structure, a forming structure and a feeding communicating structure. The traditional Chinese medicine component tablet can soften blood vessels, promote blood circulation and quickly and effectively treat cerebral arterial thrombosis, meanwhile, the production process is simple, the production efficiency is high, and industrial production is easy to achieve.

The application discloses a kind of bumetanide tablets, raw materials include bumetanide 1 according to mass ratio;Corn starch 81~85;Lactose 50~54;Agar 0.1~0.3;Povidone K304~6;Polysorbate 80, 0.1~0.2;Silicon dioxide 3~4.5;Talcum powder 2~3.3;Magnesium stearate 0.3~0.7.Its preparation method includes the following steps: pretreatment, premixing, granulation, wet granulation, drying, dry granulation, total mixing, tabletting and packaging.The application introduces the synergistic system of trace agar and polysorbate 80 in the prescription.Agar, as a natural hydrophilic colloid, can form a hydrophilic network structure during the granulation process, and synergistically act with polysorbate 80, greatly improving the wettability and dispersibility of the slurry to ultrafine bumetanide, preventing drug agglomeration, so that the drug can be more evenly distributed in the granules during the subsequent drying and tabletting process.

The utility model discloses a dustproof tabletting device for pharmacy, which belongs to the technical field of tabletting devices and comprises a processing table, and a rotary tablet press body is mounted at the top of the processing table. The protective assembly comprises a transparent protective cover; by arranging the protection assembly, the rotary tablet press is simple in structure, convenient to use and practical, the rotary tablet press body can be isolated from external air, medicine powder is prevented from polluting the processing environment, and damage to the body health of operators is also prevented; the rotary tablet press is simple in structure and convenient for operators to maintain the rotary tablet press body, medicine powder can be collected into a dust collection cloth bag by arranging a dust removal assembly, accumulation of the medicine powder on the surface of the rotary tablet press body is reduced, and the operators can conveniently collect and reuse the residual medicine powder.

The utility model belongs to the field of high polymer material heating and tabletting, in particular relates to a high polymer material heating and tabletting device, and aims to solve the problems that in the prior art, high polymer materials are placed in a forming groove to be heated and then are tabletted, however, the flaky molecular materials are left in the forming groove after being tabletted, and the working efficiency is high. According to the technical scheme, the sheet-shaped molecular material forming machine comprises a machine table, a support is welded to the top of the machine table, a driving part is fixedly arranged at the top of the support, a telescopic part of the driving part penetrates through the top of the support and is fixedly provided with a lower pressing box, and a forming box is arranged under the lower pressing box; the diameter of the lower pressing box is the same as the inner diameter of the forming box, the forming box can be turned over through the rotating mechanism after tablet pressing is completed, tablets can be poured out conveniently, the tablet taking time is greatly shortened, the production efficiency is improved, high polymer materials in the forming box can be cooled through the cooling mechanism, and a worker can hold the forming box conveniently.

This utility model provides a powder tableting mold, comprising: a base; a first gasket connected to the base; a mold cylinder disposed on the base; a second gasket including multiple second sub-gaskets, which are joined together to form the second gasket, the second gasket including a second cavity, the second gasket being disposed in the first cavity inside the mold cylinder; a pressure column disposed in the second cavity; and a pressure cap connected to the pressure column; wherein, the powder material is disposed in the second cavity, and when the pressure cap is subjected to external pressure, the pressure column compresses the powder material into shape.

The utility model discloses a guide column sealing structure which comprises a guide column body, the outer surface of the guide column body is fixedly connected with a lower installation plate, the upper surface of the lower installation plate is fixedly connected with a lower supporting block, a third pressing piece is installed on the lower supporting block, a second sealing ring is installed on the third pressing piece, and a second pressing piece is installed on the second sealing ring. A first sealing ring is mounted on the second pressing piece, a first pressing piece is mounted on the first sealing ring, an upper supporting block is mounted on the first pressing piece, an upper mounting plate and an upper supporting block are fixedly connected to the upper surface of the upper supporting block, and a positioning column is fixedly connected to the upper mounting plate. According to the double-layer sealing ring, leakage of liquid or gas can be effectively prevented by extruding the structure of the double-layer sealing ring, the multi-layer structure can better adapt to temperature and pressure changes, and the stability of the sealing performance is kept.

The invention provides a probiotic fermentation and bacterial powder compound addition chewable tablet and a preparation method thereof, and belongs to the technical field of microorganisms, the preparation method comprises the following steps: respectively adding water into apple peel, cerasus humilis fruits and aronia melanocarpa fruits, pulping, and mixing in proportion to obtain mixed fruit pulp; a mixed bacterium solution of lactobacillus plantarum LNJ-HQ-01 and lactobacillus fermentum BNCC194390 is added into the mixed fruit pulp, and fermentation is performed; freeze-drying and grinding the fermented fruit pulp to obtain freeze-dried fruit powder; the preparation method comprises the following steps: respectively activating lactobacillus plantarum LNJ-HQ-01, lactobacillus acidophilus BNCC186447 and lactobacillus rhamnosus ATCC7469, performing enlarged culture, taking bacterial sludge, uniformly mixing the bacterial sludge with a freeze-drying protective additive, and performing freeze-drying to obtain freeze-dried bacterial powder; and uniformly mixing the fruit powder, the freeze-dried bacterial powder and the medicinal auxiliary materials, and tabletting to obtain the probiotic chewable tablets. The probiotic chewable tablet is high in dietary fiber content, effective calcium content and total phenol content, high in oxidation resistance and suitable for calcium supplement of special groups such as diabetics and the like.

This invention discloses a highly active compound health supplement made from Cordyceps sinensis, Artemisia argyi, and rhubarb, and its preparation method, belonging to the field of health food and pharmaceutical preparation processing technology. The method includes: adding artificial Cordyceps sinensis ultrafine powder, prepared Rhubarb tanguticum fine powder, Artemisia argyi leaf extract, microcrystalline cellulose PH102, and maltodextrin into a mixer and premixing at 25-35 rpm to allow the powder to adhere to the surface of the excipients; after tableting, the tablets are subjected to ultra-high pressure treatment at 350-380 MPa. This invention achieves uniform distribution and performance optimization of the formulation components without damaging the activity of heat-sensitive components through precise coupling of premixing strength and ultra-high pressure modification parameters. Experiments show that the obtained formulation has an adenosine retention rate ≥96%, a dissolution rate ≥85% after 5 minutes, and excellent moisture resistance and mechanical strength, solving the technical problems of large activity loss, easy moisture absorption, and slow dissolution in traditional formulations.

The invention discloses a compound fluralab chewable tablet and a preparation method thereof, and relates to the technical field of veterinary drug preparations, the chewable tablet is composed of fluralab, pyrantel and moxidectin solid dispersion constructed by poloxamer 407 / lauryl sodium sulfate (or sodium dodecyl sulfate); preferably, the particle size D50 of the dispersion is 5-30 microns, and D90 is less than or equal to 80 microns. The preparation method comprises the following steps: firstly, dissolving moxidectin in the system to form a clear solution, drying under reduced pressure, and grinding and sieving at low temperature to obtain a dispersed material; premixing with microcrystalline cellulose, then mixing with lactose, adding a disintegrating agent and a lubricating agent, and carrying out prepressing-main pressing two-stage tabletting to obtain the tablet. The system can maintain amorphous distribution of moxidectin in the tablet, the content uniformity and dissolution and acceleration stability are remarkably improved, broad-spectrum synergy is formed by the moxidectin, the fluralasodium and the pyrantel, and the moxidectin tablet is suitable for killing fleas and ticks, treating roundworms and hookworms and preventing canine heart filariasis and tubuloidiasis.

A composite encapsulated vitamin liposome, which is prepared from the following raw materials in parts by weight: 2-65 parts of a vitamin, 15-65 parts of a phospholipid, 0.2-3 parts of an antioxidant, 1-8 parts of a membrane stabilizer, 9-45 parts of a first-layer wall material, and 4-20 parts of a second-layer wall material. A preparation method comprises: preparing an aqueous solution of a water-soluble vitamin to obtain an aqueous phase; fully mixing and dissolving anhydrous ethanol, a phospholipid and a membrane stabilizer, and then adding a lipid-soluble vitamin and allowing same to completely dissolve to obtain an alcohol phase; separately preparing a first-layer wall material solution and a second-layer wall material solution; slowly injecting the alcohol phase into the aqueous phase, and stirring same sufficiently to form a primary liposome dispersion solution; performing vacuum concentration to obtain a concentrated solution, slowly adding same to the first-layer wall material solution, and stirring same sufficiently to form a dispersion solution; and performing high speed shearing and high pressure homogenization and mixing same with the second-layer wall material solution, and performing drying to obtain the final product. The liposome can be used in the production of tablet preparations, hard-shell capsules and solid beverages, and can achieve high stability and controlled release of vitamins.

A pressing piece screwing type powder box comprises a box body and a box cover matched with the box body, a first containing groove and a pressing piece covering and pressing the first containing groove are arranged in the box body, and a powder cover is arranged in the first containing groove; a first convex rib is obliquely arranged on the side wall of the first accommodating groove, a first annular bulge is arranged at the bottom of the first accommodating groove, and a second accommodating groove for accommodating a powder cover is formed in the first annular bulge; the pressing piece is annular, a second annular protrusion is arranged at the bottom of the pressing piece, a second protruding rib is obliquely arranged on the outer wall of the second annular protrusion and extends into the limiting area to be matched with the first protruding rib, and a limiting block is arranged at the end, close to the pressing piece, of the second protruding rib. The pressing piece is convenient to disassemble, and then the powder cover is convenient to replace.

X-ray fluorescence powder tablet storage box, including box, box cover, elastic rubber sealing ring, humidity sensor, transparent partition, drawer, desiccant box, the box is connected with the box cover to form a sealing groove, the sealing groove is adapted to the elastic rubber sealing ring, the elastic rubber sealing ring is connected with the sealing groove, the sealing groove has a rubber strip groove, the elastic rubber sealing ring has a sealing rubber strip, the sealing rubber strip is adapted to the rubber strip groove, the sealing rubber strip is connected with the rubber strip groove, the box has a plurality of inner connecting plates, the box cover has a plurality of outer connecting plates, the outer connecting plates are corresponding to the positions of the inner connecting plates, the outer connecting plates have screw rods, the screw rods pass through the inner connecting plates, the screw rods are connected with nuts through threads, the nuts are attached to the inner connecting plates, the inner wall of the box is connected with S-pole magnetic stickers, the S-pole magnetic stickers are attracted to N-pole magnetic stickers, the N-pole magnetic stickers are connected with the humidity sensor.

The utility model relates to the technical field of medicine powder recovery, specifically relates to a tablet medicine powder recovery tableting device, including work table, the top fixed connection of work table is used for the rotary tableting machine of the medicine powder compression into medicine piece, the side wall fixed connection of work table's top near rotary tableting machine is used for the feeding tank of storage, the bottom shape of feeding tank is tapered, the bottom fixed connection of feeding tank is used for the feeding pipe of discharge, the side wall fixed connection of work table's top one side near rotary tableting machine has the feeding pipe, the top fixed connection of feeding pipe has the guide plate, the side wall of work table is provided with the recovery mechanism for the rotary tableting machine production when the scattered medicine powder collection and re -compression. Compared with the prior art, the present application realizes the full -automatic closed loop of medicine powder collection, screening, conveying and reflux, avoids dust overflow and manual handling, improves medicine powder utilization, reduces material waste, and significantly improves production efficiency and environmental cleanliness.

The application provides a resin type artificial stone chemical component analysis device, and relates to the technical field of material spectrum analysis. The device comprises an infrared spectrometer, a driving mechanism, a pretreatment assembly and a tablet pressing mechanism. One side of the infrared spectrometer is provided with a detection table. The surface of the detection table is provided with a detection groove. The surface of the detection groove is screwed with an inclined plate. The middle of the inclined plate is integrally formed with a positioning table. The surface of the positioning table is provided with a hole. One end of the infrared spectrometer is built with a tablet pressing mechanism. The middle of the detection groove is inserted with a driving mechanism. The single driving mechanism is used for simultaneously controlling the slow rotary motion of the two groups of pretreatment assemblies, so that the sample preparation and detection process can be synchronized, the utilization rate of the power equipment is improved, and the analysis efficiency is improved. The sample pretreatment, detection analysis and post-cleaning can be quickly and seamlessly connected, and the automatic resetting process is realized.

The utility model provides pressure regulation and control equipment for a tablet press, which relates to the technical field of tablet presses and comprises a regulation and control mechanism, an auxiliary mechanism is arranged on the inner wall of one end of the regulation and control mechanism, the regulation and control mechanism comprises a connecting column, a pressing plate is arranged on the outer side of the connecting column, and the outer side of the connecting column is in sliding connection with the inner wall of one end of the pressing plate. A first adjusting arm is arranged on the top side of the pressing plate, and the top side of the pressing plate is movably connected with the bottom end of the first adjusting arm. By rotating the first lead screw, the locking ring is separated from the first adjusting arm, at the moment, the first adjusting arm is pulled in the second adjusting arm, then the overall length of the adjusting arm is increased, the pressure can be naturally changed due to the increase of the length, and the flexible pressure regulation and control design can meet the pressing requirements of different types of materials, for example, the pressing efficiency is greatly improved. And for materials with different densities or particle sizes, the consistent tabletting effect can be ensured by adjusting the pressure.

The utility model relates to the technical field of medicine tabletting, in particular to a tablet medicine tabletting device. The device comprises a bottom box, a hydraulic cylinder is fixedly installed on the inner bottom wall of the bottom box, and a sheet discharging mechanism is fixedly installed on the top of the hydraulic cylinder; a tablet pressing plate is fixedly installed on the top face of the bottom box, a moving mechanism is fixedly installed on the edge of one side of the tablet pressing plate, the surface of the moving mechanism is in threaded connection with a transverse moving frame, and a powder discharging mechanism is fixedly arranged on the inner wall of the transverse moving frame. According to the tablet medicine tabletting device, through the arrangement of a transverse moving frame and a powder discharging mechanism, medicine powder is put into a medicine powder barrel and communicated with an external power source, a servo motor drives a threaded lead screw to rotate, so that the transverse moving frame transversely moves above a tabletting plate, a pneumatic conveying pump is started, and high-pressure gas is fed into the medicine powder barrel through a gas conveying pipe; and the medicine powder is conveyed to the powder conveying pipe and put into the tabletting groove from the powder outlet, so that the effect of automatically putting the medicine powder is achieved, and the tabletting efficiency of the tablet medicine is improved.

The invention discloses a compound special diet and a preparation method thereof, and belongs to the technical field of special diets. The diet is prepared from 40-45 parts of cassia seed powder as a main raw material, 17-22 parts of compound black bean powder, 10-16 parts of collagen peptide powder and the like as well as 1-2 parts of a compound coating agent (not included in a formula proportion). The preparation method comprises the steps of sieving, ingredient mixing, dry granulation, tabletting, coating and inner packaging, wherein the sieving adopts a 40-mesh sieve, the mixing is carried out for 30 minutes at the speed of 40HZ, the dry granulation ensures that the granularity is greater than or equal to 70%, the tablet weight is controlled to be 0.78-0.82 g during tabletting, the hardness is controlled to be 90-150N during tabletting, and the coating adopts specific parameters. Through synergistic interaction of the raw materials and process optimization, the activity of the components is reserved, the stability and palatability of the product are guaranteed, the method is suitable for industrial production, and the special dietary function requirements are met.

The utility model provides a solid -liquid separation bottle lid of integral type, this solid -liquid separation bottle lid of integral type includes: lid body, the top of lid body is provided with the bunker, press release subassembly, press release subassembly includes convex press part, press tablet and aluminium foil, the convex press part sets up at the bunker top, the aluminium foil is sealed in the bunker bottom end, is provided with press tablet between the convex press part and aluminium foil, sealing ring, sealing ring sets up in the inner wall of lid body. Integral type design collocation convex press part, can effectively with solid such as press tablet and external liquid isolate storage. When the bottle lid is not pressed, solid is safely sealed in the bunker, is completely isolated with outside liquid, avoided because of the problem such as early mixing and leading to the reduction of drug efficacy or the use effect is poor, perfect satisfaction solid -liquid separation actual demand, cleverly the simple structure, functional practicality and scientific rationality of design are organically combined together.