12 results about "Xanthoxylin" patented technology

The invention discloses a broad-spectrum combined medicine for treating liver cancer, which comprises purified water, tripterygium wilfordii alkaloid, tripterygium hypoglaucum alkaloid, chamaejasmine, gelsmium elegans alkaloid, xanthoxylin and various B medicines, and further comprises folic acid, vitamins, copper sulfate, zinc sulfate, manganese sulfate, yeast and penicillin sodium. Through the multi-component, multi-target and multi-path design, the medicine disclosed by the invention shows a potential effect of inhibiting the progress of liver cancer and good safety in cell experiments, animal models and human individual case observation. Cellular immunity and humoral immunity can be enhanced, the treatment cost is lower than that of a traditional treatment scheme, and no pain is caused during treatment.

The invention relates to a traditional Chinese medicine composition which comprises more than 1.09 permillage of ephedrine hydrochloride, more than 0.86 permillage of pseudoephedrine hydrochloride, more than 0.17 permillage of peiminine, more than 0.03 permillage of peimine, more than 0.17 permillage of chrysin-7-O-glucuronide, more than 0.002 permillage of glycyrrhetinic acid, more than 11.87 permillage of amygdalin and more than 0.01 permillage of neotuberostemonine. The oral liquid is prepared from more than 2.16 per mill of glycyrrhizic acid, more than 1.97 per mill of oroxylin A, more than 1.97 per mill of oroxylin B, more than 1.23 per mill of liquiritin, more than 0.59 per mill of apiose liquiritin, more than 0.55 per mill of baicalin, more than 0.23 per mill of chlorogenic acid, more than 0.18 per mill of praeruptorin A, more than 0.15 per mill of wild melanosin, more than 0.14 per mill of methyephedrine hydrochloride, more than 0.13 per mill of isoliquiritin, more than 0.13 per mill of neochlorogenic acid and more than 0.13 per mill of cryptochlorogenic acid. The composition is prepared from more than 0.10% of peimine, more than 0.08% of baicalein, more than 0.05% of praeruptorin B, more than 0.04% of praeruptorin C, more than 0.011% of xanthoxylin and more than 0.0006% of formononetin.

The invention provides a broad-spectrum combined medicine for treating colorectal cancer. The broad-spectrum combined medicine is prepared from the following components in parts by weight: 100 parts of purified water, 38 to 90 parts of tripterygium wilfordii alkaloid, 38 to 90 parts of tripterygium hypoglaucum alkaloid, 28 to 85 parts of chamaejasmine, 28 to 85 parts of gelsmium elegans alkaloid and 28 to 85 parts of xanthoxylin. The medicine is prepared from the following raw materials in parts by weight: 16 to 80 parts of ganoderan, 16 to 80 parts of pinellia ternate sitosterol, 16 to 80 parts of radix rehmanniae praeparata, 16 to 80 parts of astragaloside, 16 to 80 parts of oldenlandia diffusa alkaloid, 16 to 80 parts of sculellaria barbata alkaloid, 16 to 80 parts of tanshinone, 16 to 80 parts of carthamin, 16 to 80 parts of honeysuckle chlorogenic acid and 16 to 80 parts of pericarpium citri reticulatae flavone. By integrating anti-tumor components with multiple action mechanisms, tripterygium wilfordii alkaloid, tripterygium hypoglaucum alkaloid and the like, tumor cell proliferation can be directly inhibited, and apoptosis can be induced; tanshinone, emodin and the like can inhibit tumor angiogenesis; ganoderma lucidum polysaccharides, astragaloside and the like can activate the immune system of the body, enhance the activity of T cells and NK cells, and form double strikes of direct killing and immune surveillance.

The invention belongs to the technical field of xanthoxylin application, and particularly discloses application of xanthoxylin WGX-50 in preparation of a medicine for treating pathogenic bacteria induced broiler inflammatory depletion diseases, and the xanthoxylin WGX-50 can be used as a poultry feed additive. In-vitro experiments show that 20 [mu] M of WGX-50 significantly alleviates the toxicity of LPS-induced chicken macrophages, and the cell activity is improved to 103.74%. In-vivo 21d broiler chicken feeding tests prove that by adding 100mg / kg WGX-50 into daily ration, a synergistic effect can be generated: the total antioxidant capacity of an organism is remarkably enhanced, and the level of pro-inflammatory cytokines is reduced; meanwhile, the average daily gain of the broiler chickens is remarkably increased, the feed-gain ratio is reduced, and the metabolic rate of key nutrient substances such as crude protein, calcium and phosphorus is increased. According to the invention, a brand new solution is provided for the WGX-50 in the aspects of precise prevention and control of poultry inflammatory depletion diseases and improvement of breeding benefits through a clear action mechanism and dosage.

The utility model provides a xanthoxylin mask spraying device, and belongs to the technical field of mask processing. Comprising a recycling assembly, the recycling assembly is arranged at the bottom of a fixed outer plate, the recycling assembly comprises a collecting plate fixed to the bottom of the fixed outer plate, a connecting box is fixed to the top of the collecting plate, fans are evenly arranged in the connecting box, a collecting bin is fixed to the bottom of the collecting plate, and the recycling assembly is installed at the bottom of the fixed outer plate; the collecting plate fixed to the bottom of the fixed outer plate plays a basic role in bearing spraying waste, after a connecting box at the top of the collecting plate and fans evenly distributed in the collecting plate are started, strong suction force is generated, waste such as xanthoxylin falling or splashing in the spraying process is guided to the collecting bin fixed to the bottom through the collecting plate, and therefore efficient recycling is achieved, and the waste recycling effect is good. Waste materials are prevented from polluting the environment; and subsequent treatment is facilitated.

This invention relates to a recombinant bacterial cell for de novo synthesis of xanthocyanin WGX-50 using glucose as a carbon source, its construction method, and its applications. The recombinant bacterial cell uses *Escherichia coli* as the host strain and integrates the following three heterologous biosynthetic modules: a 3,4-dimethoxyphenylethylamine de novo synthesis module, which contains an enzyme system catalyzing the generation of dopamine from L-tyrosine and further stepwise methylation of dopamine to 3,4-dimethoxyphenylethylamine; a cinnamoyl-CoA synthesis module, which contains an enzyme system catalyzing the generation of cinnamoyl-CoA from phenylalanine or glucose metabolic intermediates; and an amidation module, which contains an acyltransferase capable of catalyzing the condensation of 3,4-dimethoxyphenylethylamine and cinnamoyl-CoA to generate xanthocyanin WGX-50. This invention achieves, for the first time, the de novo biosynthesis of xanthocyanin in microorganisms, completely eliminating dependence on the expensive exogenous precursor 3,4-dimethoxyphenylethylamine and significantly reducing raw material costs.

The invention discloses a preparation method and a use method of an efficient non-toxic insecticidal and bactericidal nutrient solution biopesticide. The biopesticide is prepared from plant-derived active ingredients such as tripterygium wilfordii alkaloid, omphalia, chamaejasmine, capsaicin, xanthoxylin and pomegranate alkaloid, vitamins B2 and B6 and trace element salts such as copper sulfate, zinc sulfate, manganese sulfate and potassium sulfate according to a specific weight part ratio. The preparation method comprises the steps of mixing the components, homogenizing and the like. The application method comprises the steps of spraying after dilution, direct broadcast application, soil treatment or stem injection. The product provided by the invention has prevention and treatment effects on various diseases and insect pests, can supplement nutrients for crops and promote growth, and is environment-friendly and free of toxic residues.

The invention relates to a nasal spray for prevention and adjuvant therapy of cognitive impairment and a preparation method thereof, and belongs to the field of health-care medicines. The formula of the nasal spray for prevention and adjuvant treatment of cognitive impairment comprises the following components in percentage by volume: a solvent the balance of water; 2%-5% of butanediol; 2%-5% of glycerin; active components: 0.01%-0.1% of a bay leaf extract; 0.01% to 0.1% of a bacopa monnieri extract; 0.01%-0.05% of a radix salviae miltiorrhizae extract; the efficient penetration enhancing and feeling adjusting components comprise 0.001%-0.1% of xanthoxylin and 0.001%-0.01% of eucalyptus globulus leaf oil; 0.001% to 0.01% of menthol; the nasal spray prepared by the invention is a composite plant extract nasal spray which is safe, effective and convenient to use, has a multi-target synergistic effect and has high brain-targeted delivery efficiency.

This invention discloses the application of zanthoxylin in the preparation of plant-based herbicides and the resulting herbicides, relating to the field of herbicide technology. The concentration of zanthoxylin in the plant-based herbicides is ≥20 μg / mL. By using zanthoxylin as the active ingredient in plant-based herbicides, it exhibits significant growth inhibition against various common farmland weeds at a concentration ≥20 μg / mL. Furthermore, this active ingredient is derived from natural plants and is a biodegradable secondary metabolite, making it less likely to leave residues in the environment and causing no soil degradation or water pollution. Compared to chemically synthesized herbicides, it is more ecologically safe. This not only provides a new option for developing efficient, broad-spectrum, and environmentally friendly bio-based herbicides but also expands the application prospects of zanthoxylin in the agricultural field.

The invention discloses a method for preparing high-purity xanthoxylin through catalysis, and belongs to the technical field of chemical synthesis. The method comprises the following steps: reacting a cinnamic acid derivative and homoveratramine in an organic solvent in the presence of a boron catalyst; after the reaction is finished, the xanthoxylin with the purity of more than 99.5% is obtained through simple treatment. The invention provides an economical and efficient amplification preparation method of xanthoxylin, the product purity is high, and wide application of xanthoxylin in the aspects of aging resistance, virus resistance, inflammation resistance and the like is expected to be promoted.

The invention discloses a traditional Chinese medicine formula for treating gastric cancer as well as a preparation method and application thereof. The formula is prepared from the following components in parts by weight: monarch drugs: 38-90 parts of tripterygium wilfordii alkaloid, 38-90 parts of tripterygium hypoglaucum alkaloid, 28-85 parts of chamaejasmine, 28-85 parts of gelsemium elegans alkaloid and 28-85 parts of xanthoxylin; ministerial and adjuvant drugs: 16 to 80 parts of ganoderan, 16 to 80 parts of pinellia ternate sitosterol, 16 to 80 parts of radix rehmanniae praeparata catalpol, 16 to 80 parts of amomum cardamomum volatile oil, 16 to 80 parts of piper cubeba element, 16 to 80 parts of dendrobine, 16 to 80 parts of alpinia katsumadai volatile oil, 16 to 80 parts of panax notoginseng ginsenoside, 16 to 80 parts of linalool, 16 to 80 parts of caulis spatholobi element, 16 to 80 parts of cassia seed element, 16 to 80 parts of bergamot alcohol, 16 to 80 parts of cistanche deserticola, 16 to 80 parts of fructus forsythiae alkaloid and 16 to 80 parts of mulberry inorganic salt; 16 to 80 parts of total flavonoids of sea-buckthorn; and 100 parts of water. Wherein the ratio of the total parts by weight of the monarch drugs to the total parts by weight of the ministerial and adjuvant drugs is 1: (1.5-5.0). The traditional Chinese medicine formula for treating gastric cancer provided by the invention has the advantages of obvious curative effect, multi-target synergistic effect, high safety and controllable toxicity, and can improve the living quality of patients.

The invention discloses a broad-spectrum combined medicine for treating lung cancer. Comprising tripterygium wilfordii alkaloid, tripterygium hypoglaucum alkaloid, chamaejasmine, gelsemium elegans alkaloid, xanthoxylin, ginsenoside, American ginseng amino acid, radix pseudostellariae fructose, codonopsis pilosula alkaloid, bulbus fritillariae cirrhosae alkaloid, houttuyfonate, amomum cardamomum volatile oil, bergamot alcohol, radix ophiopogonis glucose, polygonatum quinones, lotus plumule alkaloid, pericarpium citri reticulatae volatile oil, glycyrrhizic acid, cassia seed element and carthamin. The traditional Chinese medicine composition is prepared from lily colchicine, Chinese yam germanium, baicalein, silybum marianum volatile oil, pueraria isoflavone, oriental wormwood flavone, thunberg fritillary bulb alkali, linalool, mulberry inorganic salt, poria cocos hypoglycan, selaginella doederleinii hieron alkaloid, selfheal triterpenoid saponin, salvianolic acid, lycium barbarum proteoglycan, angelica sinensis volatile oil, sculellaria barbata alkaloid, oldenlandia diffusa alkaloid, fructus forsythiae alkaloid, astragalus membranaceus flavone and menthol. The feed additive is prepared from red date cyclic adenosine monophosphate, hawthorn flavone, panax notoginseng ginsenoside, folic acid, vitamins, copper sulfate, zinc sulfate, manganese sulfate, yeast and penicillin sodium.