184 results about "Ephedrine" patented technology

A composition for suppressing appetite and cravings for substances such as nicotine, coffee, sweets or chocolate while improving energy and enhancing mood comprises theobromine or a salt thereof at an effective amount of from about 250 to 4000 mg. Using such relatively high proportions of theobromine, without added caffeine or ephedrine provides an effective method for promoting weight control or to halt substance cravings without the side effects associated with such stimulants. The composition also includes Rhodiola rosea extract to offset stress effects from reduced food or substance intake, and to further improve mood, and clarity of thought and ability to handle stress, and to also increase endurance while reducing muscle pain.

The invention relates to a method for simultaneously detecting seven slimming chemical components which are illegally added to traditional Chinese medicine, health food or cosmetics. According to the method, an appropriate mobile phase and a reasonable elution gradient are adopted during liquid-phase separation, so that the slimming components needing to be detected are effectively separated within 12 min, the analysis time of a sample instrument is shortened by 88%, and the work efficiency is greatly increased. Additionally, the advantages of high separation ability of the HPLC (High Performance Liquid Chromatography) technology, high sensitivity and stronger qualitative ability of the mass spectrum and the like are combined, so screening and confirmation can be simultaneously completed during one operation. By using the method disclosed by the invention, the seven chemical components including sibutramine, fenfluramine, phenolphthalein, ephedrine, caffeine, N,N-bi-demethylation sibutramine and furosemide can be effectively separated, the inspection time can be shortened, and the slimming chemical components which are illegally added to the traditional Chinese medicine, the health food or the cosmetics can be accurately and effectively distinguished.

Chewing gum compositions comprising synephrine, ephedrine and caffeine are provided. The compositions are useful for supporting thermogenesis and anorectic effects, while generating enhanced mental alertness and improved energy levels.

Ethamine compound is obtained by condensing starting materials of 6-bromoisovanillin and tyramine under catalysis of NaBH4 in carbinol. In formylation of ethamine compound, aminic acid and formaldehyde of same amount are used to produce formyl compound, with temperature between 90 DEG C. and 110 DEG C., 8h. Racemic bromonarwedine is obtain by oxidation and cyclization of the formyl compound. Racemic narwedine is obtained by reduction reaction under catalysis of NaCO2H, PPh3, Pd(OAc)2. Racemic narwedine is transformed into (-)-narwedine by a process of crystal inoculation. (-)-narwedine is reduced into unsaturated ketone by (-)-N-methyl ephedrine as chiral reagent, whereby optically active alcohol is obtained, and (-)-galanthamine is also obtained.

The invention discloses a pharmaceutical composition for ventilating lung and relieving asthma, a preparation method and a quality control method. The pharmaceutical composition comprises the following pharmaceutical raw materials: ephedra herb, raw ginger, cassia twig, bitter apricot seed, Chinese magnoliavine fruit (prepared) and prepared liquoric root, the preparation method is as follows: the five herbal medicines except the bitter apricot seed are decocted by adding water through a countercurrent circulatory extraction process and concentrated to obtain a clear paste after reducing pressure, ethanol is added, then the mixture is stirred evenly and placed staticly, supernatant liquid is taken, the ethanol is recovered, and the concentration is carried out to obtain a thick paste; the bitter apricot seed is arranged in a hot pressure sterilization pot for hot pressure steaming and boiling and then is arranged in a small amount of cold water for soaking instantly after being taken out, an apricot processed product can be obtained by removing seed coats and being dried; the quality control method is as follows: the thin layer identification is carried out on the ephedra herb, the raw ginger and the liquoric root, the content measurement is carried out on ephedrine in the ephedra herb and schizandrin in the Chinese magnoliavine fruit. The pharmaceutical composition has good effects on ventilating lung and relieving asthma.

The air-vapor coupling vapor exploding ephedrine wall breaking process includes the following steps: 1. setting cut ephedra material inside vapor exploding tank with air and steam as vapor exploding medium, introducing air to pressure 5-10 kg/sq cm, fast introducing steam to pressure 10-18 kg/sq cm, steam exploding for 2-20 min, opening the discharge ball valve fast to spray the ephedra material into normal pressure releasing tank; and 2. 2-4 stage water soaking and boiling extraction of the steam exploding wall breaking treated ephedra material at 80-100 deg.c for 30-120 min to obtain ephedrine aqua in high lixiviating rate. The present invention has the advantages of mild steam explosion condition, no loss of the Chinese medicine components, high extracting rate, simple operation, low cost, less exhausted waste water with organic matter and high material utilization rate.

The invention provides a medicine composition containing matrine class alkaloid, a preparation method and pharmaceutical applications. The medicine composition is the combination of the matrine class alkaloid and inflammation-resisting pain-relieving class medicines. The inflammation-resisting pain-relieving medicine comprises the non-steroidal inflammation-resisting medicines of aspirin, acetaminophen, indometacin, ibuprofen, oxyphenbutazone, naproxen, mefenamic acid, diclofenac sodium, celecoxib, rofecoxib, valdecoxib and the like and also comprises the vegetable inflammation-resisting pain-relieving class medicines of escin, ferulic acid, berberine, wilfordine, ephedrine and the like and the pain-relieving class medicines of morphia, demerol and the like. The matrine class alkaloid and one or various of the inflammation-resisting pain-relieving class medicines can form a medicine composition used for the pharmaceutical applications of resisting cold, allaying a fever and treating the swelling and pain of the bone joint and the muscle, rheumatic diseases, cardiovascular diseases, arteriosclerotic diseases, tumors, anaphylactic diseases, senile dementia, mosquito bite, insect bite and the like.

The invention provides a medicine for treating diabetes. The medicine uses ginseng, Radix Ophiopogonis, Chinese yam, Rhizoma Anemarrhenae, Ligustri Lucidi Fructus, Yetbadetajo Hert, roasted Rhizoma Atractylodis Macrocephalae, Radix Astragali, Peach Seed, Radix Paeoniae Rubra, Cortex Moutan, Medicinal Cyathula Root, Fructus Arctii, unprepared rehmannia root, Cortex Lycii and Trichosanthis Radix as raw materials, or uses ginseng, Ephedrine alkaloid, Cattail Pollen flavone, Radix Angelicae Pubescentis, beta-oleyl alcohol of Leaf of Tasmanian Bluegum, Angelica polymorpha Maxim, Radix Puerariae, Rhizoma Anemarrhenae, Ligustri Lucidi Fructus, Yetbadetajo Hert, roasted Rhizoma Atractylodis Macrocephalae, Peach Seed, Cortex Moutan, Medicinal Cyathula Root, Fructus Arctii, Radix Scrophulariae, Cortex Lycii and Herba Leonuri as raw materials, or uses ginseng, epigallocatechin gallate, Myricaria laxiflora, Angelica polymorpha Maxim, Radix Ophiopogonis, Yetbadetajo Hert, white peony root, Peach Seed, Cortex Moutan, Medicinal Cyathula Root, Fructus Arctii, Radix Scrophulariae, Cortex Lycii, Radix Scutellariae, Corsvenor Momordica Fruit and mulberry leaf as raw materials, or uses ginseng, tea polyphenol, konjak, Chaenomeles Speciosa(sweet) Nakai, Radix Ophiopogonis, Yetbadetajo Hert, Peach Seed, Chinese yam, Medicinal Cyathula Root, Cortex Moutan, Chinese magnoliavine, berberine, 3-6 parts of Radix Scrophulariae, mulberry leaf, Cortex Lycii, unprepared rehmannia root and Trichosanthis Radix as raw materials. The medicine has simple and unique formula and preparation method.

The invention discloses a method for producing ephedrine through imine reductase, and belongs to the technical field of biology. The invention provides the method for producing ephedrine through iminereductase. By the method, (R)-1-phenyl-2-carbonyl-3-propanol and methylamine are used as reaction raw materials, a reaction is performed for 18h, and the yield of the ephedrine in reaction liquid canbe as high as 86.5%; by the method, benzaldehyde, pyruvate and methylamine are used as reaction raw materials, a reaction is performed for 18h, and the yield of the ephedrine in the reaction liquid can be as high as 62.7%; and therefore, the method has the advantage of being high in yield when being used for producing the ephedrine.

Disclosed herein are storage-stable ephedrine single-phase solution compositions, comprising 4 mg/mL to 6 mg/mL of ephedrine, a pH adjuster comprising acetic acid, and water, wherein the composition has a pH between 4.5 and 5.0; and wherein the pH drift of the composition is less than 0.5 after storage over at least two months at 25° C. and 60% relative humidity. Also disclosed herein are methods of making and using the same.

A method of inhibiting or preventing the use of anhydrous ammonia as a solvent in a dissolving metal reduction process comprises adding to anhydrous ammonia a chemical reagent which is capable of scavenging solvated electrons generated when alkali or alkaline earth metal is dissolved in the anhydrous ammonia, the chemical reagent being added to the anhydrous ammonia such that when alkali metal is dissolved in the anhydrous ammonia containing the chemical reagent and thereafter ephedrine, pseudoephedrine or combination thereof is introduced to the anhydrous ammonia to produce a reaction product, the methamphetamine yield in the reaction product is below 50%, preferably below 10%, and more preferably below 1%. Preferred chemical reagents include Fe(III)citrate, ferrocene, 2-chloro-6-(trichloromethyl)pyridine and 1,1,1,2-tetrafluoroethane.

The invention relates to the technical field of medicines for anesthesia, in particular to a traditional Chinese medicine composition for the anesthesia and a preparation method of the traditional Chinese medicine composition. Raw materials, namely honeysuckle, ephedrine, maca powder, poppy powder, silktree albizia bark, radix zanthoxyli and radix angelicae, are combined, a pharmaceutical auxiliary material is added into a preparation technology, nutritional ingredient contents of the raw materials are further adjusted, and a tablet is prepared, so that the traditional Chinese medicine composition can be absorbed in a tablet form to reach an effect of the anesthesia; in addition, due to the combination of the traditional Chinese medicines, the medicine for the anesthesia does not bring an side effects after taken; adverse effects such as indigestion and shiver after the anesthesia are avoided; and injuries to a human body due to the anesthesia are reduced.

The present invention is drawn to an ephedra- and artificial stimulant-free energy promoting composition, comprising effective amounts of a magnesium amino acid chelate, a B vitamin, a pyruvate salt, and rhodiola. These ingredients work synergistically together to provide energy, without the use of artificial stimulants, caffeine, or ephedrine. Additional amino acid chelates can also be present, such as iron amino acid chelate, zinc amino acid chelate, copper amino acid chelate, manganese amino acid chelate, chromium amino acid chelate, and mixtures of second amino acid chelates.

The invention discloses a combination containing r-chlorpheniramine, which is formed by the r-chlorpheniramine and the medicine salt and the other or a plurality of active ingredients or pharmaceutical carriers selected from non-steroidal anti-inflammatory drug, ephedrine alkaloids, coffeine, dextromethorphan hydrobromide, carbetapentane citrate, glyceryl guaiacolate, bromhexine hydrochloride, artificial cow-bezoar, amantadine hydrochloride, aminophylline and zinc gluconate. The orally taken preparation developed from the combination comprises granule, tablet, capsule, dispersible tablet, chewable tablet, effervescent tablet, orally disintegrating tablet, buccal tablet, dry suspension and certain solid formulation.

The invention relates to the traditional Chinese medicine pharmacy field, in particular to a Chinese medicinal herb used for curing diseases such as colds and coughs and acute and chronic tracheitis, etc. The Chinese medicinal herb comprises four medicines of monarch drug in a prescription, adjuvant drug, adjuvant and conductant drug. The oral preparation is prepared by using existing conventional traditional Chinese medicine pharmacy technique and excipients, wherein, the components of the medicine are moxibustion ephedrine, bitter almond, cordate houttuynia, agrimony, golden buckwheat rhizone, geranium nepalense, prunella, caladium, cicada slough, larva of a silkworm withbatrytis, scorpion, lumbricus, chilopod and liquorice. The invention has more satisfactory healing efficacy on coughs and acute and chronic tracheitis which are caused by colds; the total cure rate is 78.08% and the total effective rate can reach 95.47%.

The invention discloses a method for detecting a Chinese medicinal composition for freeing lung and relieving asthma. The Chinese medicinal composition consists of the following raw material medicines: ephedra, ginger, cassia twig, bitter apricot seed, Chinese magnoliavine fruit (prepared) and roasted liquorice. The detection method comprises the steps of detecting the ephedrine content of the ephedra and detecting the Schizandrol content of the Chinese magnoliavine fruit.

The invention belongs to the field of gel preparation and particularly relates to compound nasal gel for treating allergic rhinitis and a preparing method thereof. The compound nasal gel is prepared from baicalin, carbomer, ephedrine hydroehloride, borax, glycerin, ethylparaben, menthol, ethanol and distilled water. The nasal gel spray has the advantages of accurate therapeutic effect, stable properties and small adverse reaction is prepared through the selection of the baicalin which has remarkable antimicrobial, anti-inflammatory and anti-allergic effects, the cold-irritating menthol and a low dosage of ephedrine hydroehloride and the use of the high-molecular carbomer as a carrier. The compound nasal gel is used for treating allergic rhinitis.

A quality control method for the solid medicine í‹QianbaiíŒ used to treat rhinitis features that a thin-layer chromatography is used for qualitative identification to senscio, ephedra, notopterygium root and other components, and an efficient liquid-phase chromatography is used to measure the content of ephedrin.

The invention relates to an extraction process of ephedrine, and belongs to the technical field of extraction of effective components in traditional Chinese medicines. The process provided by the invention comprises the following steps: pretreatment of ephedra; alkalization; extraction with xylene; extraction; concentration; and the like. By adopting the processes such as alkalization, extraction with xylene and extraction with oxalic acid, tedious processes in the prior art can be simplified, and high purity ephedrine can be quickly and effectively extracted.

A novel and efficient alkylation procedure of B—H-1,3,2-oxazaborolidines derived from ephedrine and norephedrine has been established. Representative B-butyl- and B-methyl-1,3,2-oxazaborolidines were prepared in good yield and excellent purity by one pot treatment of the parent boraheterocyclic compound with the corresponding organolithium reagent and subsequent hydrolysis of the cyclic borohydride with anhydrous ammonium chloride.

Procedure for preparation of compounds with the general formula 1, which include the racemic mixtures (±)-1, and the enantiomeric ally pure compounds (−)-1 and (+)-1, wherein R₁ and R₃, like or different, represent an atom of hydrogen, chlorine, fluorine, a methyl, trifluoromethyl or methoxy group; R₂ represents an atom of hydrogen, chlorine, fluorine, a methyl, trifluoromethyl, methoxy, trifluoromethoxy, methylsulphonyl or aminosulphonyl group; R₄ represents an atom of hydrogen, chlorine, fluorine, a methyl, trifluoromethyl, methoxy, trifluoromethoxy, methylsulphonyl or aminosulphonyl group, with the condition that one of the substituents R₂ or R₄ is a methylsulphonyl or aminosulphonyl group; which involves obtaining the racemic mixture with the general formula (±)-1 by reacting an (E)-1,1,1-trifluoro-4-aryl-3-buten-2-one with a phenylhydrazine, followed by a treatment with chlorosulphonic acid, or by reacting with chlorosulphonic acid followed by a reaction with sodium hydroxide and, finally, with thionyl chloride. The product obtained by either of these methods is made to react with ammonium carbonate or ammonia, or with sodium sulphite and methyl iodide or methyl sulphate. In addition, to obtain the enantiomerically pure compounds with the general formula 1 by resolving the racemic mixture with the general formula (±)-1, a reaction is effected with optically active ephedrine, followed by formation of the sodium salt of each enantiomer, reaction with thionyl chloride and ammonium carbonate or ammonia, or instead with thionyl chloride followed by sodium sulphite and methyl iodide or methyl sulphate to thereby obtain separately the enantiomerically pure compounds with the general formulae (−)-1 and (+)-1.

The invention discloses a denitrification method for sewage. The denitrification method comprises the following steps: (1) mixing a proper amount of montmorillonite powder with ephedrine and a nitration microbial agent and allowing nitrated microbes to be closely adhered on the surface of montmorillonite, wherein the nitration microbes and the montmorillonite are closely bonded to form an interaction body; (2) adding the interaction body into sewage in a nitration reaction tank, carrying out contact culture for 7 days under aerobic conditions and allowing ammonia nitrogen to fully undergo nitration, thereby converting ammonia nitrogen into nitrate nitrogen; (3) allowing sewage having undergone nitration to enter a denitrification reaction tank after precipitation and adding a denitrification bacterial agent for anaerobic denitrification; and (4) subjecting treated water obtained after denitrification to precipitation so as to realize nitrogen removal. The particle size of the montmorillonite is in a range of 50 to 1000 nm, and the addition amount of the montmorillonite is 0.001% to 0.005% of the mass of the sewage; the addition amount of the nitration microbial agent is 0.0001% to 0.0005% of the mass of the sewage; and the addition amount of the ephedrine is 0.002% to 0.006% of the addition amount of the nitration microbial agent.

The invention discloses compound datura flower asthma relieving powder for treating respiratory tract infection of pigs and a preparation method thereof, and aims to provide compound datura flower asthma relieving powder for treating the respiratory tract infection of the pigs with quick response, safe use, effectiveness, high efficiency and treatment of both symptoms and root causes and a preparation method thereof with simple process and easy implementation. The compound datura flower asthma relieving powder comprises the following compositions in percentage by weight: 10 to 30 percent of datura flower, 5 to 15 percent of ephedrine, 10 to 20 percent of bitter apricot seed, 5 to 15 percent of oxytetracycline, 10 to 20 percent of alum and the balance of gypsum. In the compound powder combining Chinese and Western medicaments, the Chinese medicaments such as the datura flower, the ephedrine, the bitter apricot seed, the alum, the gypsum and the like have the effect of relieving asthma and cough, and the oxytetracycline has the effect of broad-spectrum resistance to pathogenic microorganisms, so the compound powder is effective to various bacteria and mycoplasma causing the respiratory tract infection of the pigs, can effectively treat the respiratory tract infection and cough, asthma and the like caused by the respiratory tract infection, has quick response, and treats both the symptoms and the root causes.