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302 results about "Metabolic rate" patented technology

Metabolic calorimeter employing respiratory gas analysis

An indirect calorimeter for measuring the metabolic rate of a subject includes a respiratory connector configured to be supported in contact with the subject so as to pass inhaled and exhaled gases as the subject breathes, a flow pathway, and a hygiene barrier positioned to block a predetermined pathogen from the exhaled gases. The indirect calorimeter also includes a flow pathway having a first end in fluid communication with the respiratory connector and a second end in fluid communication with a source and sink for respiratory gases. The flow pathway includes a flow tube through which the inhaled and exhaled gases pass, an outer housing surrounding the flow tube, and a chamber disposed between the flow tube and the first end. The indirect calorimeter also includes a flow meter configured to generate electrical signals as a function of the instantaneous flow volume of inhaled and exhaled gases passing through the flow pathway, and a component gas concentration sensor operable to generate electrical signals as a function of the instantaneous fraction of a predetermined component gas in the exhaled gases as the gases pass through the flow pathway. The indirect calorimeter further includes a computation unit operable to receive the electrical signals from the flow meter and the concentration sensor and operative to calculate at least one respiratory parameter for the subject as the subject breathes through the calorimeter.
Owner:MICROLIFE MEDICAL HOME SOLUTIONS

Thermal and humid environment integrated control air-conditioning system and method based on thermal comfort evaluation

The invention provides a thermal and humid environment integrated control air-conditioning system and method based on thermal comfort evaluation. The comfort operating level and the corresponding PWV numerical range of an air conditioner are set in strict accordance with national standards, the air conditioner is made to have the humidification adjusting function, an average thermal sensation index PMV value is calculated by acquiring air temperature, relative air humidity, average radiation temperature, wind speed, metabolic rate and clothing thermal resistance and compared with a preset comfort PMV value interval, and the air supply speed, the refrigerating / heating operating state and the humidifying / dehumidifying operating state of the air conditioner are intelligently adjusted according to the comparison result, so that a target area is in a comfort state satisfying the human body, the comfort requirement of the human body is met, the thermal comfort environment of the target area is easily improved, and energy conservation and emission reduction of a building are promoted. The principle and parameter setting of the system and method are scientific, and the operation method is simple and easy to control and implement.
Owner:CHONGQING UNIV

Complementary metabolizing organisms and methods of making same

InactiveUS20090023182A1Impaired metabolic capacityIncrease metabolic rateFermentationMicrobiology processesOrganismBiology
The invention provides a non-naturally occurring set of microbial organisms. The set of organisms includes: at least a first constituent complementary metabolizing organism (CMO) exhibiting the ability to metabolize a first carbon substrate and having substantially impaired metabolic capacity for a second carbon substrate, and at least a second constituent complementary metabolizing organism (CMO) exhibiting the ability to metabolize the second carbon substrate and having substantially impaired metabolic capacity for the first carbon substrate, wherein a co-culture of the at least first and second CMOs exhibit simultaneous metabolism of a mixture having the first and second carbon substrates compared to either CMO alone. Simultaneous metabolism of a mixture having first and second carbon substrates can include an enhanced rate of metabolism of the first and second substrates compared to either CMO alone. Also provided is a bioprocess for producing a chemical compound. The bioprocess includes co-culturing a non-naturally occurring set of microbial organisms in a mixture having at least a first and a second carbon substrate under conditions sufficient for biosynthesis of a target chemical compound, the set of non-naturally occurring microbial organisms including: at least a first constituent complementary metabolizing organism (CMO) exhibiting the ability to metabolize the first carbon substrate and having substantially impaired metabolic capacity for the second carbon substrate, and at least a second constituent complementary metabolizing organism (CMO) exhibiting the ability to metabolize the second carbon substrate and having substantially impaired metabolic capacity for the first carbon substrate, wherein a co-culture of the at least first and second CMOs exhibit simultaneous metabolism of a mixture having the first and second carbon substrates compared to either CMO alone. Simultaneous metabolism of a mixture having first and second carbon substrates can include an enhanced rate of metabolism of the first and second substrates compared to either CMO alone.
Owner:GENOMATICA INC

Passive Microwave Assessment of Human Body Core to Surface Temperature Gradients and Basal Metabolic Rate

InactiveUS20120029369A1Enhances ability to quantifyEnhances to mapThermometers using value differencesBody temperature measurementDiseaseHuman body
A passive microwave thermography apparatus uses passive microwave antennas designed for operation, for example, at WARC protected frequencies of 1.400 to 1.427 GHz and 2.690 to 2.70 GHz (for core body gradient temperature measurement) and 10.68 to 10.700 GHz or higher microwave frequency (for surface body gradient temperature measurement) and a related directional antenna or antenna array to measure microwave radiation emanating from an animal, especially, a human body. The antennae may be radially directed toward a point within or on the surface of a human body for comparison with known temperature distribution data for that point and a given ambient temperature. Each frequency band may provide a plurality of adjacent noise measuring channels for measuring microwave noise naturally emitted by the human body. The apparatus measures short-term changes in, for example, core and body surface temperatures to establish a basal metabolic rate. Changes in core body temperature may be stimulated by the administration of food or certain organic and drug-related substances or stress to induce a change in basal metabolic rate over time. These changes correlate directly with a human subject's metabolism rate at rest and under certain dietary constraints and can be used to determine courses of treatment for obesity, metabolic disease, and other disorders. The apparatus can also be used to remotely monitor patients and subjects without physical contact.
Owner:ICOVE DAVID +3

Method of providing customized drug delivery systems

InactiveUS20060078621A1Promote absorptionMaximum therapeutic effectivenessPowder deliveryPill deliveryAdditive ingredientBlood plasma
A novel method of correlating the disposition of a specific drug in an individual patient to a controlled and modulated delivery system for optimizing therapeutic response of orally ingested dosage forms is provided. Such a method broadly encompasses a first determination of an individual's metabolic rate in terms of absorption of pharmaceutical materials from within the gastrointestinal tract measured as blood plasma concentration over a specific period of time after ingestion or by other commercially available methods and subsequent determination: 1) predicting a proper pharmaceutical compositions, in terms of amount of active available for absorption by the target patient; and 2) amount of such active pharmaceutical ingredient (API) to be formulated within a drug-delivery device that will take into account the unique metabolic profile of the drug (or drugs) in a specific patient. As a result, the API may be formulated as beads, pellets, minitablets, powders, granules, suspensions, and / or emulsions present within the drug-delivery source. As one potentially preferred embodiment, such beads and / or pellets, which may be coated with different polymers and differing levels of coatings, are selected in response to the initial determination of the patient's metabolic profile in order to ensure the specific targeted patient receives the most efficient dosage of the active drug at a rate unique to that individual.
Owner:J M HUBER CORP
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