304 results about "Metabolic rate" patented technology

An indirect calorimeter for measuring the metabolic rate of a subject includes a disposable portion and a reusable portion. The disposable portion includes a respiratory connector configured to be supported in contact with the subject so as to pass inhaled and exhaled gases as the subject breathes. The disposable portion also includes a flow pathway operable to receive and pass inhaled and exhaled gases, having a first end in fluid communication with the respiratory connector and a second end in fluid communication with a source and sink for respiratory gases. The disposable portion is disposed within the reusable portion, which includes a flow meter, a component gas concentration sensor, and a computation unit. The flow meter generates a signal as a function of the instantaneous flow volume of respiratory gases passing through the flow pathway and the component gas concentration sensor generates a signal as a function of the instantaneous fraction of a predetermined component gas in the exhaled gases. The computation unit receives the electrical signals from the flow meter and the concentration sensor and calculates at least one respiratory parameter for the subject as the subject breathes through the calorimeter.

A magnetic nerve stimulator system is comprised of a core constructed from a material having a high field saturation with a coil winding. A thyrister capacitive discharge circuit pulses the device. A rapidly changing magnetic field is guided by the core, preferably vanadium permendur. For task specific excitation of various nerve groups, specially constructed cores allow for excitation of nerves at deeper levels with higher efficiency than is possible with air-core stimulators. Among the applications possible with this invention are treatment of incontinence, rehabilitation of large muscle groups in the leg and arm, and excitation of abdominal wall muscle groups to aid in weight loss and metabolic rate increase. A C-shape is employed for focussing the stimulation as desired.

A respiratory analyzer comprises a flow module, having a flow tube through which the flow rate of gases is determined using a flow rate meter, and a computation module, in communication with the flow module, operable to determine a flow rate of respired gases. The computation module may also be operable to determine a metabolic rate of the subject.

A breath test for determining the rate of metabolism of a drug is described. First, a safe and effective amount of the drug, preferably appropriately labelled and most preferably isotopically-labelled, is administered to a subject. After a suitable time period, the exhaled breath of the subject is analyzed to determine the concentration of a metabolite. The concentration of the metabolite is then used to determine the rate of metabolism of the drug. A breath test kit is also described. Such a breath test kit would include an item or items necessary for performing at least one of the methods of determining the rate of metabolism of a drug in a subject. For example, such a breath test kit could include an isotopically-labelled drug to be administered to the subject.

The invention provides a thermal and humid environment integrated control air-conditioning system and method based on thermal comfort evaluation. The comfort operating level and the corresponding PWV numerical range of an air conditioner are set in strict accordance with national standards, the air conditioner is made to have the humidification adjusting function, an average thermal sensation index PMV value is calculated by acquiring air temperature, relative air humidity, average radiation temperature, wind speed, metabolic rate and clothing thermal resistance and compared with a preset comfort PMV value interval, and the air supply speed, the refrigerating / heating operating state and the humidifying / dehumidifying operating state of the air conditioner are intelligently adjusted according to the comparison result, so that a target area is in a comfort state satisfying the human body, the comfort requirement of the human body is met, the thermal comfort environment of the target area is easily improved, and energy conservation and emission reduction of a building are promoted. The principle and parameter setting of the system and method are scientific, and the operation method is simple and easy to control and implement.

The invention provides a non-naturally occurring set of microbial organisms. The set of organisms includes: at least a first constituent complementary metabolizing organism (CMO) exhibiting the ability to metabolize a first carbon substrate and having substantially impaired metabolic capacity for a second carbon substrate, and at least a second constituent complementary metabolizing organism (CMO) exhibiting the ability to metabolize the second carbon substrate and having substantially impaired metabolic capacity for the first carbon substrate, wherein a co-culture of the at least first and second CMOs exhibit simultaneous metabolism of a mixture having the first and second carbon substrates compared to either CMO alone. Simultaneous metabolism of a mixture having first and second carbon substrates can include an enhanced rate of metabolism of the first and second substrates compared to either CMO alone. Also provided is a bioprocess for producing a chemical compound. The bioprocess includes co-culturing a non-naturally occurring set of microbial organisms in a mixture having at least a first and a second carbon substrate under conditions sufficient for biosynthesis of a target chemical compound, the set of non-naturally occurring microbial organisms including: at least a first constituent complementary metabolizing organism (CMO) exhibiting the ability to metabolize the first carbon substrate and having substantially impaired metabolic capacity for the second carbon substrate, and at least a second constituent complementary metabolizing organism (CMO) exhibiting the ability to metabolize the second carbon substrate and having substantially impaired metabolic capacity for the first carbon substrate, wherein a co-culture of the at least first and second CMOs exhibit simultaneous metabolism of a mixture having the first and second carbon substrates compared to either CMO alone. Simultaneous metabolism of a mixture having first and second carbon substrates can include an enhanced rate of metabolism of the first and second substrates compared to either CMO alone.

A passive microwave thermography apparatus uses passive microwave antennas designed for operation, for example, at WARC protected frequencies of 1.400 to 1.427 GHz and 2.690 to 2.70 GHz (for core body gradient temperature measurement) and 10.68 to 10.700 GHz or higher microwave frequency (for surface body gradient temperature measurement) and a related directional antenna or antenna array to measure microwave radiation emanating from an animal, especially, a human body. The antennae may be radially directed toward a point within or on the surface of a human body for comparison with known temperature distribution data for that point and a given ambient temperature. Each frequency band may provide a plurality of adjacent noise measuring channels for measuring microwave noise naturally emitted by the human body. The apparatus measures short-term changes in, for example, core and body surface temperatures to establish a basal metabolic rate. Changes in core body temperature may be stimulated by the administration of food or certain organic and drug-related substances or stress to induce a change in basal metabolic rate over time. These changes correlate directly with a human subject's metabolism rate at rest and under certain dietary constraints and can be used to determine courses of treatment for obesity, metabolic disease, and other disorders. The apparatus can also be used to remotely monitor patients and subjects without physical contact.

The invention discloses a comfort control method of an air conditioner. The method comprises the steps that when it is detected that the comfort control of the air conditioner is started, a target comfort level is obtained; the indoor environment temperature, the dress heat resistance, the human body metabolic rate and the radiation temperature are obtained; the target comfort level, the indoor environment temperature, the dress heat resistance, the human body metabolic rate and the radiation temperature are substituted into a preset comfort level formula, and a comfort curve with wind speed and humidity associated is obtained; and according to the comfort curve with wind speed and humidity associated, the air conditioner is controlled to run. The invention further discloses a comfort control device of the air conditioner. By means of the embodiment, the temperature of a room can reach and be stabilized in the most comfortable human sensation state. According to the method and the device, the temperature of the air conditioner can be stabilized within the comfort range, and the energy-saving effect of the air conditioner is achieved.

Provided are compositions comprising compounds or precursors to compounds which may be used for a variety of therapeutic applications including, for example, treating and / or preventing a disease or disorder related to reduced or inadequate mitochondrial activity, including aging or stress, diabetes, obesity, and neurodegenerative diseases. The compounds relate generally to urolithins and precursors thereof, including but not limited to ellagitannins and urolithin A. In certain embodiments the compositions are presented in or as food products or nutritional supplements. These same compounds and compositions can also be used advantageously in generally healthy individuals to increase or maintain metabolic rate, decrease percent body fat, increase or maintain muscle mass, manage body weight, improve or maintain mental performance (including memory), improve or maintain muscle performance, improve or maintain mood, and manage stress.

Methods and apparatus for preventing myocardial infarction, or lessening the size / severity of an evolving myocardial infarction, by cooling at least the affected area of the myocardium using an intravascular heat exchange catheter. The heat exchange catheter may be inserted into the vasculature (e.g., a vein) and advanced to a position wherein a heat exchanger on the catheter is located in or near the heart (e.g., within the vena cava near the patient's heart). Thereafter, the heat exchange catheter is used to cool the myocardium (or the entire body of the patient) to a temperature that effectively lessens the metabolic rate and / or oxygen consumption of the ischemic myocardial cells or otherwise protects the ischemic myocardium from undergoing irreversible damage or infarction.

The invention discloses an energy saving thermal comfort control method of an air conditioning system. The method comprises the following steps: (1) when an air conditioner is started, a preset value of thermal comfort PMV is obtained; (2) the clothing thermal resistance and the human body metabolic rate are obtained; (3) an indoor thermal environment initial state point and an energy consumption value corresponding to the initial state point are obtained; (4) an optimizing method is used for enabling a set value of the air conditioning system to continuously approach an optimal combination; and (5) when the indoor PMV value dose not satisfy a thermal comfort range, the steps (3) and (4) are repeated. The method can precisely control the thermal comfort, can effectively reduce the air conditioner energy consumption under the precondition of guaranteeing the thermal comfort, can be suitable for thermal comfort control of different building types and different air conditioning systems at different times without needing sample data, and is wide in application range.

A method is provided for correcting reference parameters based on weight variations of a subject. The parameters that can be corrected may be metabolic rate, metabolic equivalent (MET), dehydration rate, drug dosage, exercise intensity, calorie usage, work level, and oxygen consumption. A corrected parameter for a subject can be determined by the factor Pr⁢(wts)xyto obtain a corrected parameter (Ps). In the factor, wts is the weight of the subject, x is preferably ⅓, Pr is the reference parameter to be corrected, and y is preferably (wtr)z, wherein wtr is the reference weight and z is preferably ⅓.

The invention discloses a method for controlling a sleep environment. The method comprises the steps: acquiring body type and person location information parameters through an infrared body sensor; detecting air humidity in a room through an air-conditioning humidity sensor module; bringing metabolic rates of different bodies and different humidity values into an PMV (Predicted Mean Vote) equation to calculate comfortable sleep temperature of males, females, children and old people; starting an air-conditioner to run at a low-wind state, enabling a wind direction to keep away from human bodies and regulating the present sleep setting temperature according to a setting temperature reading table calculated according to the PMV equation. The invention further discloses an air-conditioner for controlling the sleep environment. An input module, an output module and a power supply are respectively connected with an MCU (Micro Controller Unit); the infrared body sensor and the air-conditioning humidity sensor module are respectively connected with the input module. The beneficial effect is as follows: the air-conditioner is applicable to controlling different people to enter comfortable sleep state.

An exsanguinous metabolic support system for maintaining an organ or tissue at a near normal metabolic rate is disclosed. The system employs a warm perfusion solution capable of supporting the metabolism of the organ or tissue thereby preserving its functional integrity. The system also monitors parameters of the circulating perfusion solution, such as pH, temperature, osmolarity, flow rate, vascular pressure and partial pressure of respiratory gases, and regulates them to insure that the organ is maintained under near-physiologic conditions. Use of the system for long-term maintenance of organs for transplantation, for resuscitation and repair of organs having sustained warm ischemic damage, as a pharmaceutical delivery system and prognosticator of posttransplantation organ function is also disclosed.

Measurement of blood flow rate in a convenient manner has been enabled by using a simple device constitution and a simple signal processing technique. A measurement mechanism having both the function of measuring temperature of the measurement site and the function of applying a thermal load to the measurement site is used, and a process of extracting temperature change associated with the recovery of the surface temperature by the blood flow is conducted from the measurement results obtained by the measurement mechanism.

The invention is a product that produces a feeling of satiety, suppresses appetite and promotes a higher metabolic rate, while providing nutrients for a balanced meal in a fruit flavored meal substitute. The product for weight management comprises fruit juice and protein, and further comprises green tea extract comprising epigallocatechin gallate. The product can be made to further comprise caffeine at a level over and above that provided by the green tea extract, and added calcium. Other aspects of the invention include methods to provide a human with a product that aids in the feeling of satiety and contributes to weight management, comprising administering to a human in need thereof the food product described.

An exsanguinous metabolic support system for maintaining an organ or tissue at a near normal metabolic rate is disclosed that employs a warm perfusion solution capable of altering the production of nitric oxide (NO) in an organ or tissue and supporting the metabolism of the organ or tissue at normothermic temperatures. Perfusion with the solution of the invention, therefore, can be used to regulate nitric oxide production in situations where it is desirable to do so, for example, to prevent reperfusion injury. The system also monitors parameters of the circulating perfusion solution, such as pH, temperature, osmolarity, flow rate, vascular pressure and partial pressure of respiratory gases, and nitric oxide (NO) concentration and regulates them to insure that the organ is maintained under near-physiologic conditions. Use of the system for long-term maintenance of organs for transplantation, for resuscitation and repair of organs having sustained warm ischemic damage, to treat cardiovascular disorders, to prevent reperfusion injury, as a pharmaceutical delivery system and prognosticator of posttransplantation organ function is also disclosed.

Compositions of peptides and surface-active agents are described, as are methods of making and using such compositions. The compositions are capable of affecting metabolic rates in biological systems, and to accelerate nutrient uptake without a concomitant increase in biofilm production.

The invention discloses a controlling method of an air conditioner. The controlling method comprises the following steps that temperature near a human body of a user, humidity near the human body of the user, clothing thermal resistance, the human metabolic rate, the air speed near the human body of the user and ambient radiation temperature in the environment where the air conditioner is locatedare acquired; the comfortable degree of the human body is calculated according to the clothing thermal resistance, the human metabolic rate, the temperature near the human body, the humidity near thehuman body, the air speed near the human body and the ambient radiation temperature; and operation of the air conditioner is controlled according to the comfortable degree of the human body. The invention also discloses the air conditioner. The operation of the air conditioner is controlled according to the accurately calculated comfortable degree of the human body, maintenance of the better comfortable degree of the human body of the user is guaranteed and applicability of the air conditioner is improved.

A novel method of correlating the disposition of a specific drug in an individual patient to a controlled and modulated delivery system for optimizing therapeutic response of orally ingested dosage forms is provided. Such a method broadly encompasses a first determination of an individual's metabolic rate in terms of absorption of pharmaceutical materials from within the gastrointestinal tract measured as blood plasma concentration over a specific period of time after ingestion or by other commercially available methods and subsequent determination: 1) predicting a proper pharmaceutical compositions, in terms of amount of active available for absorption by the target patient; and 2) amount of such active pharmaceutical ingredient (API) to be formulated within a drug-delivery device that will take into account the unique metabolic profile of the drug (or drugs) in a specific patient. As a result, the API may be formulated as beads, pellets, minitablets, powders, granules, suspensions, and / or emulsions present within the drug-delivery source. As one potentially preferred embodiment, such beads and / or pellets, which may be coated with different polymers and differing levels of coatings, are selected in response to the initial determination of the patient's metabolic profile in order to ensure the specific targeted patient receives the most efficient dosage of the active drug at a rate unique to that individual.

The invention discloses a dietetic food composition for losing weight. The composition comprises the following ingredients: fresh meat and aquatic product, vegetables, fruits, dried mushroom products, cereals, beans, nut meat, edible vegetable oil, eggs, protein hydrolysate powder, dietary fiber powder, konjac powder, guar gum, polyols, phosphatidylcholine, fruit polyphenols, L-carnitine, vitamin A, vitamin E, vitamin C, thiamine hydrochloride, riboflavin, nicotinamide, pyridoxine hydrochloride, folic acid, cyanide-containing cobalt and pantothenic acid. By adopting the dietetic food composition disclosed by the invention, the total energy intake is reduced under the premise of ensuring normal basic metabolic rate, the requirements of the body on protein at a low-energy diet period are improved, and related nutrients are replenished to facilitate body fat, visceral fat and blood lipid metabolism, so as to achieve the target of losing weight. Meanwhile, the invention also discloses a preparation method of the dietetic food composition and use of the dietetic food composition in preparation of a medicament for preventing or treating an obesity disease.

A system and method for determining an individualized drug dosage is provided. The system includes a metabolic rate sensing means for sensing the metabolic rate of the individual. The system also includes a computing device having a processor, a memory, an input device, and a display device. The system further includes a data storage means operatively in communication with the processor, and the data storage means includes a drug database containing drug dosage data. The method includes the steps of determining a standardized dosage for a drug. The method also includes the steps of measuring the actual metabolic rate of the individual and determining a metabolic comparison factor by comparing the measured actual metabolic rate to a predetermined standard metabolic rate. The method further includes the steps of adjusting the standardized drug dosage using the comparison factor.

An exsanguinous metabolic support system for maintaining an organ or tissue at a near normal metabolic rate is disclosed. The system employs a warm perfusion solution capable of supporting the metabolism of the organ or tissue thereby preserving its functional integrity. The system also monitors parameters of the circulating perfusion solution, such as pH, temperature, osmolarity, flow rate, vascular pressure and partial pressure of respiratory gases, and regulates them to insure that the organ is maintained under near-physiologic conditions. Use of the system for long-term maintenance of organs for transplantation, for resuscitation and repair of organs having sustained warm ischemic damage, as a pharmaceutical delivery system and prognosticator of posttransplantation organ function is also disclosed.

The invention discloses a non-invasive blood glucose detection sensor integrator which is improved from a non-invasive blood glucose detection sensor probe and is a second-generation non-invasive blood glucose detection sensor probe. The detection voltage of the probe is 5v. The probe comprises a pedestal (1), a finger surface blood flow velocity detection zone(2), a human body local(finger) metabolic rate detection zone(3), a finger tip blood oxygen infrared detection zone(4), a circuit connection zone(5), and a signal input and output zone(6). The sensor probe is capable of non-invasively, quickly and accurately detecting the relevant parameters for calculating blood glucose time after time, and is simple to use, suitable for families, simple in fabrication technique and method and suitable for mass production.

Disclosed are several embodiments of wearable cooling devices for applying low temperatures to the human body for the purpose of inducing calorie burn over and above resting metabolic rate, even if the wearer is resting, and for the ultimate purpose of weight loss. It is an objective of this disclosure to describe the wearable cooling devices so that low temperatures are applied comprehensively over regions of the body that will induce significant calorie burn. A further objective of this disclosure is to describe garments that effectively exchange heat from a tight skin-to-garment interface that covers a large surface area of the body.

The invention discloses a control method and system for improving the comfort of an air conditioner sleeping mode. The control method comprises the following steps that the gender and / or the age groupof a user are detected; the outdoor air temperature, the indoor air temperature and the indoor air humidity are collected in real time, the average of the outdoor air temperature and the indoor air temperature is set as the average radiation temperature, and a target temperature value is calculated by substituting clothing heat resistance, air velocity parameters and human body metabolic rate parameters into a PMV equation, wherein the clothing heat resistance and the air velocity parameters are preset by an air conditioner; and the frequency and operating mode of a compressor are adjusted through a 0.1-DEG C precise temperature control technology, and thus the temperature is adjusted to the target temperature. The precise target temperature value can be calculated through a fitting function, real-time precise adjustment can be achieved, and the heat comfort of the user under the sleeping state is significantly improved.

A method of smart and energy-saving environmental control includes the following steps: collecting a plurality of physiological information and location information of users and environmental information through a plurality of sensors; identifying an active state of each of the users according to the physiological information and the location information, and getting a metabolic rate corresponding to the active state; determining a plurality of weights based on types or levels of the users, and selecting one model from the energy-saving regulation models to serve as a selected model according to the number of the users and the weights; setting an energy-saving regulation value based on the active states, the weights and the selected model; and regulating environmental control devices according to the energy-saving regulation value. Thus, the method provided by the invention considers the respective state and preference of the plurality of users to seek optimal energy-saving regulation.

The invention discloses a method for controlling humidity under an air conditioner sleeping environment. The method comprises the first step of calculating to obtain a first relative humidity value according to the preset environment temperature, the preset air conditioner air speed, the preset clothes thermal resistance corresponding to an operating mode, a preset human energy metabolic rate and a PMV index, and the second step of detecting a second relative humidity value under the air conditioner environment, comparing the first relative humidity value with the second relative humidity value and controlling a humidity adjustor according to the comparative result. The invention further discloses an air conditioner and the humidity adjustor. The air conditioner and the humidity adjustor are used for achieving the method for controlling the humidity under the air conditioner sleeping environment. According to the method for controlling the humidity under the air conditioner sleeping environment, the air conditioner and the humidity adjustor, the humidity can be adjusted according to the change of the preset temperature, and the comfort level of a user is obviously improved.