17 results about "Lethargy" patented technology

This invention provides the use of Yigongsan in the treatment of myelodysplastic syndrome (MDS). Specifically, this invention has found that Yigongsan improves ineffective hematopoiesis in MDS patients and significantly alleviates traditional Chinese medicine symptoms of MDS, such as fatigue, lethargy, lack of thirst, and sallow complexion. Furthermore, it has been discovered that Yigongsan regulates hematopoietic function in MDS through the S100A9-TLR4-NF-κB signaling pathway. This invention also provides a treatment method for MDS.

The invention belongs to the technical field of medicines, and particularly discloses a preparation method and application of a medicine extracted from gynura procumbens, fermented soya beans and chilies and used for preventing or treating polyuria and sleep disorders. Dry powder of corresponding extracts is obtained from gynura procumbens, fermented soya beans and chilies through certain extraction reagents, then the three kinds of powder are mixed, then the mixed powder and auxiliary materials are mixed and granulated, and the medicine for preventing or treating polyuria and sleep disorders is obtained. Experiments prove that the traditional Chinese medicine composition has the curative effects of improving polyuria and sleep disorders: 1) inhibiting excessive generation of urine, and remarkably reducing the frequency of urination day and night; (2) the sleep latency period is short, the sleep rate is increased, drowsiness or faint sleep caused by medicines is eliminated, and the sleep quality is improved;

This invention discloses a warming and dispersing medicinal and edible composition and its preparation method. This invention relates to the field of traditional Chinese medicine health food technology. The active ingredients of the composition are extracted from the following medicinal and edible materials: 3-10 parts by weight of dried ginger, 2-8 parts by weight of cinnamon, 5-15 parts by weight of Allium macrostemon, and 10-30 parts by weight of Astragalus membranaceus. Small molecule extract particles are prepared through processes such as β-cyclodextrin inclusion and wet granulation, significantly improving the dissolution rate and bioavailability of the active ingredients. The product is also convenient to prepare, easy to carry, and suitable for long-term use. In terms of safety, all raw materials are medicinal and edible substances. Clinical trials have proven that the overall effective rate for symptoms of Yang deficiency such as aversion to cold, cold limbs, lethargy, and loose stools is over 94%, with no obvious toxic side effects. It can be safely used for daily health maintenance and auxiliary conditioning of those with Yang deficiency and cold constitution. Pure coconut powder is used as a flavoring material, resulting in a rich aroma and good taste.

This application relates to the field of psychophysiological monitoring and data analysis technology, specifically an artificial intelligence-based dynamic stress and emotion analysis method and system. The method includes the following steps: collecting students' physiological data and body movement data while they are performing hazardous tasks; analyzing the physiological data and body movement data based on a preset algorithm to determine if the students have negative emotions, including anxiety, tension, fear, anger, and lethargy; issuing an early warning signal when negative emotions are detected and initiating a response procedure to notify relevant personnel, including users, rescue personnel, and students; generating a health feedback report and sending it to users, including teachers, instructors, and project leaders. This application has the capability to efficiently and in real-time monitor and analyze the psychological stress and emotional state of large groups in complex and high-risk work environments, particularly in educational practice training and emergency situations.

Methods and formulations for treating autism with neurotensin R1 agonists without causing significant lethargy in a subject.

The invention discloses a traditional Chinese medicine conditioning wine beverage and a preparation method thereof. The traditional Chinese medicine composition is prepared from 8-12 parts of rhizoma curculiginis, 8-12 parts of herba epimedii, 15-25 parts of codonopsis pilosula, 8-12 parts of eucommia ulmoides, 15-25 parts of semen ziziphi spinosae, 15-25 parts of American ginseng, 8-12 parts of angelica sinensis, 8-12 parts of fructus psoraleae, 8-12 parts of deer-horn glue, 8-12 parts of cistanche, 15-25 parts of astragalus membranaceus, 30-50 parts of lycium ruthenicum, 3-7 parts of liquorice, 15-25 parts of salvia miltiorrhiza, 3-7 parts of safflower carthamus, 8-12 parts of cynomorium songaricum, 8-12 parts of dogwood, 8-12 parts of semen cuscutae, 15-25 parts of pseudo-ginseng, 20-40 parts of wild gastrodia elata, 15 The traditional Chinese medicine composition has the functions of dredging meridians and collaterals, tonifying kidney and qi, replenishing blood and conditioning, relieving back pain and lassitude, and regulating frequent urination, uric acid, tinnitus, cold feet and the like, and has the functions of tonifying kidney and qi, replenishing blood and conditioning. And the comprehensive traditional Chinese medicine conditioning wine is safe to take for a long time, clear in color, good in taste and stable in medicine effect.

This invention provides a treatment for patients with developmental and epileptic encephalopathy (DEE) that addresses behavioral problems in addition to seizures, without causing undesirable side effects such as somnolence, lethargy, withdrawal, and sedation. [Solution] A method is provided for treating behavioral problems and seizures in a subject having DEE, comprising administering an effective amount of cannabidiol (CBD) transdermally to the subject, wherein the behavioral problems are treated in the subject.

A cyclic olefin derivative having an orexin 2 receptor (OX2R) agonistic activity. In particular, the present invention relates to a compound as represented by general formula (I), a stereoisomer thereof, a tautomer thereof, a pharmaceutically acceptable salt thereof, and pharmaceutically acceptable salts of the stereoisomer and tautomer. The present invention also relates to a pharmaceutical composition containing the compound, a preparation method therefor, and the use thereof as an orexin 2 receptor (OX2R) agonist for preventing or treating diseases related to the agonistic effect of an orexin 2 receptor (OX2R), such as narcolepsy, lethargy, sleep apnea, anesthesia recovery or respiratory inhibition improvement. Each substituent in general formula (I) is the same as that defined in the description.

The present invention addresses the problem of providing a composition for increasing vigor / vitality or a composition for improving lethargy / lassitude.　Provided is a composition for increasing vigor / vitality or a composition for improving lethargy / lassitude that contains an agrimol. Provided is a composition for increasing vigor / vitality or a composition for improving lethargy / lassitude that contains an agrimony extract as an agrimol. The present invention makes it possible to provide a composition for increasing vigor / vitality or a composition for improving lethargy / lassitude.

Provided is an agent for preventing or ameliorating renal function decline, the agent containing a compound represented by structural formula (1).

The invention relates to the technical field of health-care drinks, and discloses a formula and process of a medicinal tea combined drink capable of refreshing mind, and the medicinal tea combined drink is prepared from the following raw materials: ginseng decoction pieces, lily bulbs, Chinese wolfberry fruits, rhizoma polygonati, mint and jasmine green tea. The medicinal tea combined beverage is prepared from the following raw materials in parts by mass: 1-8g of ginseng decoction pieces; 1-4g of lily; 1-4g of fructus lycii; 1-4g of rhizoma polygonati; 1-4g of mint; 1-8 g of jasmine green tea; the raw materials in the formula are safe and reliable, free of sugar, free of additives and free of burden, all the raw materials are selected from medicine and food dual-purpose traditional Chinese medicines, the formula is reasonable, the selected medicines are smooth and solid, the whole formula is a product for tonifying qi and nourishing yin, supplemented with a product for nourishing kidney and liver, tonifying qi and yin, regulating multiple internal organs and balancing cold and warm, and the effects of tonifying qi, maintaining mental tranquility, restoring consciousness and relieving restlessness are achieved together. The traditional Chinese medicine composition has a good effect of relieving physical and mental fatigue, symptoms include fatigue, limb sleepiness, wandering, inattention, lie-loving, dizziness, headache and the like, and can meet the anti-fatigue and health-preserving health-care requirements of people with most physiques.

The system according to the embodiment aims to detect resident slacking or lethargy and improve their motivation. [Solution] A system according to an embodiment includes a collection unit, a determination unit, and a provision unit. The collection unit collects the resident's smartphone usage history or the operation status of home appliances. The determination unit analyzes the data collected by the collection unit and determines whether the resident is "slacking" or "lethargic." The provision unit provides words to improve motivation based on the determination result obtained by the determination unit.

This invention provides a hemp seed protein peptide that enhances immunity and serum protein levels, along with its preparation method and applications, belonging to the field of hemp seed protein peptide technology. The preparation method includes: pulverizing defatted hemp seed meal and sequentially subjecting it to hydrolysis by a complex polysaccharide enzyme, a protease, and an amidase to obtain an enzymatic hydrolysate. This hydrolysate is then processed to obtain the hemp seed protein peptide. The complex polysaccharide enzyme is a combination of cellulase, pectinase, and xylanase; the protease is pepsin; and the amidase is PNGase F. The hemp seed protein peptide of this invention has the following significant effects: 1. Significantly improves serum albumin, immunoglobulin, prealbumin, and total protein levels and immunity in middle-aged and elderly individuals, those with weak constitutions / poor nutritional status, and those recovering from illness / surgery; 2. Rapidly improves fatigue symptoms in these individuals, such as emaciation, weakness, lethargy, and poor sleep, boosting energy and relieving limb heaviness and soreness.

The invention discloses application of rubber tree seed oil in preparation of a product for improving or treating kidney-yang deficiency, and belongs to the technical field of medicines. The hevea brasiliensis seed oil can improve the levels of serum adrenocorticotropin releasing hormone, adrenocorticotropin and corticosterone by adjusting the hypothalamus-pituitary-adrenal axis function so as to improve the related signs of kidney-yang deficiency, such as intolerance of cold and liking warm, cold limbs, lassitude, reduced autonomous activity and the like. The invention further discloses a composition containing the hevea brasiliensis seed oil. The composition can be prepared into medicines, health-care foods or functional foods. The invention provides a new choice which is single in component, clear in mechanism, safe and effective for the treatment of kidney-yang deficiency.

The present invention relates to dosing regimens and methods of using LY3154207, also described as 2-(2,6-dichlorophenyl)-1-[(1S,3R)-3-(hydroxymethyl)-5-(3-hydroxy-3-methylbutyl)-1-methyl-3,4-dihydroisoquinolin-2 (1H)-yllethanone, and / or pharmaceutical compositions thereof, for treatment of dopaminergic central nervous system disorders. Dopaminergic CNS disorders of the present dosing regimen methods include Parkinson's Disease, Alzheimer's Disease, Lewy body dementia (LBD), Vascular Dementia, Schizophrenia, ADHD, Depression, Autism, chronic musculoskeletal pain, fibromyalgia, cognitive impairment disorders, sleep disorders, excessive daytime sleepiness, narcolepsy, shift work disorder, traumatic brain injury, chronic traumatic encephalopathy, obesity and appetite regulation, mood disorders, lethargy, apathy, and addiction disorders.

This invention provides a hemp seed protein peptide for improving mental and physical fatigue, its preparation method, and its applications. It belongs to the field of hemp seed protein peptide technology. The method includes extracting hemp seed protein solution using an alkali-soluble acid precipitation method; performing three-step enzymatic hydrolysis steps using Serratia marcescens, thermophilic protease, and flavor protease to obtain the final hydrolysate; and performing post-treatment and drying to obtain the final product. Clinical studies of the hemp seed protein peptide prepared by this invention have shown that: 1. It significantly relieves mental fatigue: promotes nitric oxide production, increases brain oxygen and blood supply; rapidly boosts spirits within 15 minutes, improves concentration and reaction time; and maintains energy levels for a long time, improving lethargy. 2. It significantly relieves physical fatigue: rapidly reduces lactic acid and urea nitrogen accumulation, relieves muscle soreness; increases energy reserves, provides sustained anti-fatigue, extends endurance by 2-4 hours, and maintains physical strength; significantly shortens the recovery period after excessive fatigue, improves postoperative limb heaviness and soreness, and promotes immune recovery.

Methods and formulations for treating autism with neurotensin RI agonists without causing significant lethargy in a subject.