12 results about "Poor sleep" patented technology

The present invention relates to an oral extract composition comprising Shatavari (Asparagus racemosus Willd.) and Fenugreek (Trigonella foenum-graecum L.) extract composition, and its process of preparation. Also relates to the oral extract composition formulation comprising with synergistic combinations of the Shatavari (Asparagus racemosus Willd.) and Fenugreek (Trigonella foenum-graecum L.) in suitable doses and at least one nutraceutically and / or pharmaceutically accepted excipient for, improvement, and maintenance of women health more preferably in improving of hot flashes, night sweats, poor sleep, anxiety, sexual dysfunction, mood changes, Genitourinary symptoms in overall improving the quality of life, serum estradiol, progesterone, follicle stimulating hormone (FSH), and cortisol during the period of menopause (perimenopause and menopause). The oral extract composition formulation comprising with synergistic combinations of the Shatavari (Asparagus racemosus Willd.) and Fenugreek (Trigonella foenum-graecum L.) in suitable doses and at least one nutraceutically and / or pharmaceutically accepted excipient is used for improving Brain-derived neurotrophic factor (BDNF) levels in women during the period of menopause. The present invention, further related to the extraction process of Shatavari (Asparagus racemosus Willd.) and Fenugreek (Trigonella foenum-graecum L.), also provides the process for the preparation of formulation composition. This invention further relates to the extraction process from Shatavari (Asparagus racemosus Willd.) and Fenugreek (Trigonella foenum-graecum L.) either as individual herbs or co-extraction of the two herbs or mixing the extracts at various stages of the individual extracts.

This invention belongs to the field of patch technology and relates to a sleep-aiding and hypnotic transdermal patch and its preparation method. The sleep-aiding and hypnotic transdermal patch includes a drug-loaded layer, which, by weight, comprises 2-9 parts of active drug and 0.1-7 parts of a penetration enhancer. The penetration enhancer is a combination of menthol and essential oil; the weight ratio of menthol to essential oil is 1-4:0.1-3. This invention, through optimizing the formulation and preparation process, successfully prepares a sleep-aiding and hypnotic transdermal patch with good permeability and stability, enabling slow release and absorption of the drug, solving the problems of insomnia and poor sleep quality; and reducing the probability of side effects while improving the therapeutic effect.

The invention belongs to the technical field of microorganisms and compound nutrients, and particularly relates to a postbiotic preparation and composition for improving activity of gamma-aminobutyric acid and promoting calcium absorption and application of the postbiotic preparation and composition in sleep improvement and bone health. Through the synergistic effect of the specific metagen preparation and the gamma-aminobutyric acid, the multi-dimensional technical breakthrough is realized, and the physiological activity and the application value are remarkably improved. In the aspect of bioavailability, the intestinal barrier function is improved and the pH value of the intestinal tract is adjusted to be weakly acidic through the postbiotics, so that the concentration of serum GABA is increased by 2-3 times compared with that of single use, and the calcium absorption rate is increased from 30% to 55-60%. And on the aspect of function synergy, the limitation of single effect in the prior art is broken through, dual-function synergy of'sleep regulation-bone health 'is realized, meanwhile, the vicious circle of'poor sleep-calcium loss' is improved, and good practical application value is achieved.

The invention provides an electroencephalogram micro-state recognition and sleep-aiding guiding method for a sleep transition period, and relates to the technical field of intelligent sleep aiding. The method comprises the following steps: synchronously acquiring environmental disturbance and electroencephalogram physiological signals in a sleep transition period, calculating two interference indexes of noise-electroencephalogram coupling and illumination-melatonin regulation, and carrying out normalized coupling pretreatment; a stable environment interference coupling strength index is obtained through iterative feedback, a nonlinear evolution function is matched according to interference grade branches, and a dimensionless sleep state index is generated; and dynamically adjusting an electroencephalogram micro-state matching threshold value, adapting to sleep-aiding guide parameters such as audio and light, and circularly checking the effect until the standard is reached. According to the method, the problems of inaccurate electroencephalogram micro-state recognition and poor sleep-aiding guide adaptation under bedroom low-frequency noise and illumination coupling interference are solved, the recognition precision and the sleep-aiding adaptation are improved, the sleep transition period is shortened, and the method is suitable for indoor complex interference sleep scenes.

This invention relates to the field of probiotic screening and application technology, specifically to a *Bifidobacterium longum* subsp. *longum* HC2904 that produces L-theanine, its fermentation products, and its applications. *Bifidobacterium longum* subsp. *longum* ( Bifidobacterium longum subsp. longum HC2904 was deposited with the China General Microbiological Culture Collection Center (CGMCC) on February 20, 2023, with accession number CGMCC No. 26586. This strain can produce high levels of L-theanine during the fermentation of specific raw materials, with a yield of up to 9.66 mg / mL, overcoming the technical limitations of existing probiotic technologies for improving sleep, which mainly rely on the γ-aminobutyric acid (GABA) metabolic pathway. L-theanine fermented beverages prepared from this strain can significantly improve sleep quality in people with insomnia, significantly reduce PSQI scores, and synergistically improve emotional health problems such as gastrointestinal discomfort, stress, anxiety, and depression caused by long-term poor sleep quality. It can also significantly reduce cortisol levels in the body, demonstrating a clear physiological regulatory mechanism and promising application prospects.

The application discloses a compound essential oil for soothing mood and improving sleep quality, and belongs to the technical field of aromatic health. The compound essential oil is prepared from lavender essential oil, ylang ylang essential oil, sandalwood essential oil, sweet orange essential oil, geranium essential oil, lemon essential oil, rose essential oil and frankincense essential oil, and can effectively soothe anxious mood, relax nerves, shorten sleep time and improve sleep depth. The formula is natural, mild, non-irritating and non-dependent, and is suitable for daily conditioning of people with insomnia, anxiety and poor sleep quality. The preparation process is simple, and the practicality is high.

The invention relates to the technical field of milk beverages, and provides a probiotic GABA milk beverage formula which comprises the following components: 10-15 parts of concentrated fresh milk, 30-35 parts of milk powder, 4-5 parts of pectin, 30-40 parts of chamomile and grapefruit flavored fruity sauce, 75-80 parts of mixed fruit and vegetable juice, 0.03 part of probiotics, 0.1 part of a leavening agent, 0.3-0.6 part of gamma-aminobutyric acid, 0.3-0.6 part of tea leaf theanine, 0.01-0.05 part of spina date seed powder and 0.3-1.0 part of citric acid. By scientifically compounding multiple functional factors such as GABA, tea leaf theanine and spina date seed powder, the problems of poor sleep quality, excessive mental stress and the like of modern people are remarkably improved, and probiotics in the formula are organically combined with functional active components, so that the basic effects of regulating intestinal microecology and promoting nutrient absorption of the probiotics are exerted; by optimizing the production process, the biological activity of heat-sensitive functional factors such as GABA and theanine is reserved to the maximum extent, and the influence of key parameters such as temperature and pressure on the stability of active ingredients is fully considered.

The invention relates to the technical field of health-care food, in particular to a health-care food formula for regulating the balance of internal organs of a human body. The invention discloses a health-care food formula for regulating the balance of internal organs of a human body. The health-care food formula is prepared by mixing the following raw materials in parts by weight: 1835 to 2400 parts of radix astragali seu hedysari, 1300 to 2600 parts of rhizoma dioscoreae, 1600 to 2200 parts of poria cocos, 2300 to 2800 parts of herba dendrobii, 2100 to 3250 parts of fructus crataegi, 1100 to 2000 parts of fructus hordei germinatus and 1350 to 2000 parts of fructus ziziphi jujubae. Preferably, the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 1900 to 2200 parts of radix astragali seu hedysari, 1600 to 1800 parts of rhizoma dioscoreae, 1800 to 2100 parts of poria cocos, 2300 to 2500 parts of herba dendrobii, 2600 to 3000 parts of fructus crataegi, 1500 to 1800 parts of fructus hordei germinatus and 1400 to 1600 parts of fructus jujubae. The medicinal instant granules have the beneficial effects that the clinical results of nearly 20 years prove that the medicinal instant granules have obvious conditioning effects on long-term alcoholism crowds, dark complexion crowds, poor sleep quality crowds and the like, are medicinal and edible products without adverse reactions, chemical components and additives, have the effects of dispelling the effects of alcohol, diminishing inflammation, removing freckles, improving sleep quality, soothing the liver and regulating qi and the like, and are suitable for popularization and application. The technology breaks through the traditional decocting method, and has the advantages of being convenient to carry and take and the like on the premise of not changing the effect.

The utility model relates to the field of medicine health care pillow, especially a pillow with emission channels. The common medicine pillow has the problems of poor sleep feeling, low medicine utilization efficiency, waste, groove weakening pillow supporting property, large medicine dosage and high cost, therefore, the utility model provides a pillow with emission channels, which comprises a pillow core, an accommodating cavity for storing medicine and a plurality of emission channels communicating with the accommodating cavity are arranged in the pillow core, each emission channel extends in the vertical plane, and the upper and lower ends of the emission channel extend to the top surface of the pillow core and the top wall of the accommodating cavity to form an upper opening and a lower opening. The pillow has a special channel arranged in the pillow core, which guides the medicine to volatilize and disperse upwards, has high medicine utilization efficiency and small waste, can greatly reduce the medicine dosage, has little effect on the supporting effect of the pillow core and has comfortable sleep feeling.

According to the goat milk powder capable of nourishing the stomach and soothing the nerves and the preparation method, various nutritional ingredients including high-quality raw goat milk, rich vitamins and mineral substances, isomaltooligosacharide, inulin and xylooligosaccharide are scientifically proportioned, so that comprehensive and balanced nutrition is provided, and the goat milk powder is easy to digest and absorb, is particularly suitable for people needing to nourish the stomach and soothe the nerves, and has the effects of nourishing the stomach and soothing the nerves. In addition, the added triple compound probiotic powder is beneficial to regulating intestinal flora, promoting gastrointestinal tract peristalsis, relieving constipation and reducing intestinal problems, the bovine colostrum powder is rich in immune factors, sheep spleen peptide has the effects of tonifying spleen and qi, nourishing blood and tranquilizing, the combination of the bovine colostrum powder and the sheep spleen peptide can significantly improve immunity, and meanwhile, the addition of the hericium erinaceus powder and the Chinese yam powder is beneficial to tranquilizing and stabilizing mind. The milk powder can improve the sleep quality, is especially suitable for people with large pressure and poor sleep quality, and in addition, by adopting homogenization and spray drying technologies, milk powder particles are fine and uniform and are easy to dissolve, digest and absorb.

This invention discloses a home-based sleep quality optimization aid for patients with chronic diseases, relating to the field of sleep assistance technology. It includes an adjustment controller and a wire. One end of the wire is fitted with an earplug, and the other end of the earplug is fitted with a rubber sleeve. An elastic strip is provided on the outer circumference of the earplug for conforming to the patient's concha. A detection component for detecting the patient's sleep state and a stimulation component for optimizing the patient's sleep quality are located on one side of the elastic strip. The stimulation component includes an outer sleeve fixedly connected to the elastic strip, an inner sleeve fixedly connected inside the outer sleeve, and a first electrode disposed inside the outer sleeve. This invention can effectively improve sleep problems such as difficulty falling asleep, frequent awakenings at night, and insufficient deep sleep duration in this population, breaking the vicious cycle of poor sleep quality and slow recovery, effectively optimizing the home-based sleep quality of patients with chronic diseases, and aiding in physical recovery.

This invention relates to the field of medical assistive device technology, and proposes a sleep aid device for neurology, comprising: a water filling section, which includes a water storage mechanism for holding clean water; a sound generating section, which includes a sound amplification mechanism, a drive mechanism, a water droplet emitting mechanism, a fan wheel, a rotating base, and a vibrating plate for emitting sleep-aiding sounds; and a drive section, which includes a fragrance storage mechanism and a timer speed adjustment mechanism for driving the drive source of the drive mechanism in the sound generating section. Through the coordination of the timer speed adjustment mechanism, the drive mechanism, and the water droplet emitting mechanism, different white noises can be generated, and the white noise produced by raindrops falling on different materials due to changes in wind direction can be simulated. This allows patients to continuously listen to the realistic white noise simulating raindrops falling on different materials to fall asleep, avoiding the situation where some patients are insensitive to electronic sounds played by a player, resulting in poor sleep aid effects.